## Thu Jan  2 23:20:08 2025
## emapper-2.1.12
## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/mmseqs_cluster/PRJNA951480/SRR24044403/SRR24044403_p_cluster_rep_seq.fasta --output PRJNA951480_SRR24044403 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
k59_791807_1	504472.Slin_2507	1.18e-35	142.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JRM@768503|Cytophagia	976|Bacteroidetes	T	sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8,PAS_3,PAS_9,Response_reg,Sigma54_activat
k59_869930_1	765912.Thimo_1384	1.3e-67	216.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RPQC@1236|Gammaproteobacteria,1X2A7@135613|Chromatiales	135613|Chromatiales	S	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
k59_596092_1	247633.GP2143_05985	2.31e-96	311.0	28HKI@1|root,2Z7VC@2|Bacteria,1MW0I@1224|Proteobacteria,1RQ5H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_713299_1	247633.GP2143_12826	1.67e-78	246.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,1J56B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cysteine-rich domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
k59_400392_1	118797.XP_007458897.1	5.14e-140	404.0	KOG2696@1|root,KOG2696@2759|Eukaryota,38YSJ@33154|Opisthokonta,3BG94@33208|Metazoa,3CTD0@33213|Bilateria,486FI@7711|Chordata,491VV@7742|Vertebrata,3J4SF@40674|Mammalia,4IYEQ@91561|Cetartiodactyla	33208|Metazoa	B	Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG	HAT1	GO:0000228,GO:0000785,GO:0000790,GO:0003674,GO:0003824,GO:0004402,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006335,GO:0006336,GO:0006338,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006996,GO:0007584,GO:0008080,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0010485,GO:0016043,GO:0016363,GO:0016407,GO:0016410,GO:0016569,GO:0016570,GO:0016573,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0031055,GO:0031497,GO:0031667,GO:0031974,GO:0031981,GO:0032991,GO:0034080,GO:0034212,GO:0034399,GO:0034508,GO:0034622,GO:0034723,GO:0034724,GO:0034728,GO:0036211,GO:0042221,GO:0042393,GO:0043044,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043486,GO:0043543,GO:0043933,GO:0043967,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0050896,GO:0051276,GO:0061641,GO:0061733,GO:0065003,GO:0065004,GO:0070013,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:1901564	2.3.1.48	ko:K11303	ko05034,map05034	-	-	-	ko00000,ko00001,ko01000,ko03036	-	-	-	Hat1_N
k59_1066141_1	1297569.MESS2_310018	7.24e-44	154.0	COG0006@1|root,COG0006@2|Bacteria,1MVJK@1224|Proteobacteria,2TVVP@28211|Alphaproteobacteria,43NX6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
k59_47311_2	1120970.AUBZ01000027_gene1531	1.9e-53	177.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,4654U@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide	uppS	GO:0000270,GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	iECBD_1354.ECBD_3445,iECOK1_1307.ECOK1_0175,iECSE_1348.ECSE_0173,iECW_1372.ECW_m0170,iEKO11_1354.EKO11_3744,iEcDH1_1363.EcDH1_3429,iEcE24377_1341.EcE24377A_0178,iEcHS_1320.EcHS_A0176,iNRG857_1313.NRG857_00890,iSFV_1184.SFV_0157,iUMN146_1321.UM146_23675,iUMNK88_1353.UMNK88_178,iWFL_1372.ECW_m0170,iY75_1357.Y75_RS00880	Prenyltransf
k59_478430_1	96561.Dole_2054	5.13e-87	270.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria,2MIHF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
k59_1066145_1	1121405.dsmv_1480	3.36e-83	254.0	COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,42MFY@68525|delta/epsilon subdivisions,2WJS5@28221|Deltaproteobacteria,2MJQ1@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k59_321594_1	247639.MGP2080_01776	4.47e-97	302.0	COG1506@1|root,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RR88@1236|Gammaproteobacteria,1J5WK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EU	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_988273_1	10181.XP_004840436.1	1.2e-214	598.0	COG5277@1|root,KOG0676@2759|Eukaryota,38C0D@33154|Opisthokonta,3BBGP@33208|Metazoa,3CRBJ@33213|Bilateria,480DQ@7711|Chordata,4944Y@7742|Vertebrata,3JEDP@40674|Mammalia,35F5M@314146|Euarchontoglires,4Q1SI@9989|Rodentia	33208|Metazoa	Z	postsynaptic cytoskeleton organization	ACTB	GO:0000079,GO:0000123,GO:0000902,GO:0000904,GO:0001654,GO:0001725,GO:0001932,GO:0001933,GO:0002102,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005856,GO:0005886,GO:0005912,GO:0005924,GO:0005925,GO:0005938,GO:0006469,GO:0006928,GO:0006950,GO:0006996,GO:0007010,GO:0007275,GO:0007399,GO:0007409,GO:0007423,GO:0007623,GO:0008092,GO:0008134,GO:0008150,GO:0009605,GO:0009612,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009892,GO:0009987,GO:0010033,GO:0010046,GO:0010243,GO:0010563,GO:0010605,GO:0014069,GO:0014070,GO:0015629,GO:0016020,GO:0016043,GO:0019220,GO:0019222,GO:0019894,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022898,GO:0030027,GO:0030029,GO:0030030,GO:0030036,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030424,GO:0030863,GO:0030957,GO:0031175,GO:0031248,GO:0031252,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031974,GO:0031981,GO:0032091,GO:0032268,GO:0032269,GO:0032279,GO:0032409,GO:0032432,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033673,GO:0034762,GO:0035267,GO:0035690,GO:0035770,GO:0035902,GO:0036146,GO:0036464,GO:0040011,GO:0042221,GO:0042325,GO:0042326,GO:0042493,GO:0042641,GO:0042802,GO:0042995,GO:0043005,GO:0043010,GO:0043086,GO:0043189,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043393,GO:0043549,GO:0044092,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044451,GO:0044456,GO:0044464,GO:0045121,GO:0045202,GO:0045859,GO:0045936,GO:0048468,GO:0048511,GO:0048513,GO:0048519,GO:0048523,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050789,GO:0050790,GO:0050794,GO:0050808,GO:0050896,GO:0050998,GO:0051049,GO:0051098,GO:0051100,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0051602,GO:0051621,GO:0051674,GO:0051716,GO:0051726,GO:0060041,GO:0060255,GO:0061478,GO:0061564,GO:0065007,GO:0065009,GO:0070013,GO:0070161,GO:0070887,GO:0071214,GO:0071257,GO:0071310,GO:0071407,GO:0071417,GO:0071495,GO:0071840,GO:0071900,GO:0071944,GO:0072749,GO:0080090,GO:0097237,GO:0097433,GO:0097458,GO:0097517,GO:0098589,GO:0098794,GO:0098805,GO:0098857,GO:0098918,GO:0098973,GO:0098974,GO:0098984,GO:0099173,GO:0099186,GO:0099188,GO:0099568,GO:0099572,GO:0104004,GO:0120025,GO:0120036,GO:0120039,GO:1901328,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902493,GO:1902494,GO:1902562,GO:1904029,GO:1904030,GO:1990234,GO:1990904	-	ko:K05692	ko04015,ko04145,ko04210,ko04390,ko04391,ko04510,ko04520,ko04530,ko04611,ko04670,ko04714,ko04745,ko04810,ko04919,ko04921,ko05100,ko05110,ko05130,ko05131,ko05132,ko05164,ko05205,ko05225,ko05410,ko05412,ko05414,ko05416,ko05418,map04015,map04145,map04210,map04390,map04391,map04510,map04520,map04530,map04611,map04670,map04714,map04745,map04810,map04919,map04921,map05100,map05110,map05130,map05131,map05132,map05164,map05205,map05225,map05410,map05412,map05414,map05416,map05418	-	-	-	ko00000,ko00001,ko03019,ko03021,ko03029,ko03036,ko04147,ko04812	-	-	-	Actin
k59_1223058_1	398767.Glov_2865	6.51e-91	273.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2WK33@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_556813_1	1121441.AUCX01000008_gene2250	6.26e-30	119.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2M8BJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_282418_1	335543.Sfum_2577	2.25e-78	247.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2MR42@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_165177_2	1121396.KB893071_gene1260	8.12e-51	180.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2WJ51@28221|Deltaproteobacteria,2MIT1@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	iAF987.Gmet_0119	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_988300_1	216595.PFLU_3971A	1.05e-06	54.7	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria	1224|Proteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_87421_1	909663.KI867150_gene1720	2.41e-07	49.7	290AY@1|root,2ZN0H@2|Bacteria,1P6ZU@1224|Proteobacteria,433P7@68525|delta/epsilon subdivisions,2WYJB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_243587_1	1232410.KI421418_gene2245	6.92e-100	306.0	COG2911@1|root,COG2911@2|Bacteria,1QWGG@1224|Proteobacteria,43CG1@68525|delta/epsilon subdivisions,2X7R1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_1144528_1	519989.ECTPHS_02541	5.76e-81	251.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1WWTH@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_1144528_2	596154.Alide2_4707	3.48e-15	73.6	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,4A9ZR@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_870036_1	765912.Thimo_0329	5.93e-98	297.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1WW6E@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_1105577_1	331869.BAL199_05379	6.59e-47	166.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,4BRNQ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
k59_596184_1	1049564.TevJSym_aq00810	5.8e-53	191.0	COG0674@1|root,COG1013@1|root,COG1144@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1144@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	forE	-	1.2.7.1	ko:K00171,ko:K00172,ko:K02573,ko:K03737,ko:K13795,ko:K18930	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,Fer4,Fer4_4,Fer4_6,Fer4_9,Nitroreductase,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_361410_1	1121374.KB891587_gene2982	1.25e-25	103.0	COG5505@1|root,COG5505@2|Bacteria,1RAF4@1224|Proteobacteria,1S8PC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
k59_400486_1	933262.AXAM01000010_gene1387	4.89e-26	105.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2MIHR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_439440_1	1121405.dsmv_0472	1.5e-44	155.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MJMG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_713429_1	382464.ABSI01000006_gene803	5.11e-55	182.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,HEAT_2,TetR_C_7,TetR_N
k59_47429_1	555779.Dthio_PD2257	2.08e-89	280.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2M84C@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_8447_1	246437.XP_006172159.1	0.0	892.0	COG5023@1|root,KOG1375@2759|Eukaryota,38EHS@33154|Opisthokonta,3BDQF@33208|Metazoa,3CSPW@33213|Bilateria,482T5@7711|Chordata,48VYX@7742|Vertebrata,3J4UU@40674|Mammalia,35A5V@314146|Euarchontoglires	33208|Metazoa	Z	MHC class I protein binding	TUBB	GO:0000086,GO:0000166,GO:0000226,GO:0000278,GO:0000323,GO:0001775,GO:0001882,GO:0001883,GO:0001906,GO:0001909,GO:0002228,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002449,GO:0003674,GO:0005102,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005641,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005856,GO:0005874,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007346,GO:0008150,GO:0009987,GO:0010389,GO:0010564,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016192,GO:0017076,GO:0019001,GO:0019899,GO:0019904,GO:0022402,GO:0022406,GO:0022607,GO:0030030,GO:0030031,GO:0030141,GO:0030705,GO:0031410,GO:0031625,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031982,GO:0031983,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0032940,GO:0032991,GO:0034774,GO:0035578,GO:0035639,GO:0035770,GO:0036094,GO:0036230,GO:0036464,GO:0042119,GO:0042267,GO:0042287,GO:0042288,GO:0042582,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0044085,GO:0044297,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0044877,GO:0045055,GO:0045087,GO:0045121,GO:0045298,GO:0045321,GO:0046903,GO:0046907,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051225,GO:0051234,GO:0051301,GO:0051640,GO:0051641,GO:0051649,GO:0051726,GO:0060205,GO:0060271,GO:0065007,GO:0070013,GO:0070925,GO:0071840,GO:0097159,GO:0097367,GO:0097708,GO:0097711,GO:0098589,GO:0098805,GO:0098857,GO:0099080,GO:0099081,GO:0099503,GO:0099512,GO:0099513,GO:0120031,GO:0120036,GO:0140056,GO:1901265,GO:1901363,GO:1901987,GO:1901990,GO:1902749,GO:1903047,GO:1990904	-	ko:K07375	ko04145,ko04540,ko05130,map04145,map04540,map05130	-	-	-	ko00000,ko00001,ko03036,ko04147,ko04812	-	-	-	Tubulin,Tubulin_C
k59_243648_1	246200.SPO3493	8.82e-55	185.0	COG2807@1|root,COG2807@2|Bacteria,1QXWC@1224|Proteobacteria,2TXDE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1027655_1	713586.KB900536_gene3041	1.08e-104	309.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1WW6U@135613|Chromatiales	135613|Chromatiales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_1223199_1	555779.Dthio_PD1799	3.58e-08	54.7	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2M8T9@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_478554_1	1173028.ANKO01000078_gene3903	2.47e-52	186.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase,Response_reg
k59_988428_1	338963.Pcar_2147	8.05e-75	237.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,43RZ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_791973_1	589865.DaAHT2_2117	7.92e-08	54.3	COG3005@1|root,COG3005@2|Bacteria,1NFFE@1224|Proteobacteria,430BS@68525|delta/epsilon subdivisions,2WVRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_791973_2	589865.DaAHT2_2116	5.6e-13	71.2	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL,TPR_11
k59_8496_1	398767.Glov_2977	7.73e-68	218.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2WK37@28221|Deltaproteobacteria,43TKI@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_165276_1	1121904.ARBP01000006_gene4074	4.09e-28	113.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,47K8A@768503|Cytophagia	976|Bacteroidetes	C	Monomeric isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_282543_1	1122218.KB893653_gene1376	6.96e-105	326.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria,1JTBI@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_909314_1	1384056.N787_00810	6.53e-90	278.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,1RQVT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_1027678_1	880072.Desac_1076	6.3e-51	171.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,42PD0@68525|delta/epsilon subdivisions,2WJ7K@28221|Deltaproteobacteria,2MQSG@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_243673_1	502025.Hoch_4083	5.29e-42	149.0	COG0697@1|root,COG0697@2|Bacteria,1PIFM@1224|Proteobacteria,4349X@68525|delta/epsilon subdivisions,2X51H@28221|Deltaproteobacteria,2Z2H2@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_635487_1	357809.Cphy_1186	2.56e-22	94.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,2207N@1506553|Lachnoclostridium	186801|Clostridia	CQ	BMC domain	csoS1C	-	-	-	-	-	-	-	-	-	-	-	BMC
k59_126164_1	56780.SYN_00027	5.68e-14	70.9	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MRAR@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_126164_2	290397.Adeh_3593	1.36e-44	146.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2YVK0@29|Myxococcales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_478579_1	744979.R2A130_0297	8.6e-75	236.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2TQQ4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b
k59_165290_1	1267005.KB911257_gene1106	1.36e-83	255.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2TR11@28211|Alphaproteobacteria,3N6IQ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_87535_1	765912.Thimo_2015	1.11e-49	172.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria,1WXTE@135613|Chromatiales	135613|Chromatiales	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_1027718_2	2074.JNYD01000010_gene1035	8.15e-27	106.0	COG0640@1|root,COG3832@1|root,COG0640@2|Bacteria,COG3832@2|Bacteria,2GNW2@201174|Actinobacteria,4EAJH@85010|Pseudonocardiales	201174|Actinobacteria	K	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
k59_47544_1	215803.DB30_6044	9.03e-17	87.4	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,42TQ9@68525|delta/epsilon subdivisions,2WR3B@28221|Deltaproteobacteria,2YUCZ@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
k59_321772_1	1385517.N800_01760	2.54e-86	270.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria,1X4BD@135614|Xanthomonadales	135614|Xanthomonadales	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_361535_1	319795.Dgeo_0886	7.16e-51	170.0	COG0479@1|root,COG0479@2|Bacteria,1WIEW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
k59_282602_2	158189.SpiBuddy_2278	1.54e-05	49.7	COG1011@1|root,COG1011@2|Bacteria,2J9DT@203691|Spirochaetes	203691|Spirochaetes	S	HAD-hyrolase-like	-	-	3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_596347_1	290512.Paes_2094	1.7e-28	105.0	COG2026@1|root,COG2026@2|Bacteria,1FFB4@1090|Chlorobi	1090|Chlorobi	DJ	TIGRFAM addiction module toxin, RelE StbE family	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
k59_674572_1	1121405.dsmv_2328	2.53e-70	223.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2MID0@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_1105728_1	243231.GSU0721	4.58e-46	155.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,430GK@68525|delta/epsilon subdivisions,2WVVZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma-70, region 4	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
k59_988541_2	411464.DESPIG_02498	5.94e-44	155.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2M8Q4@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_794926_1	717785.HYPMC_3257	1.32e-121	359.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,3N8ZI@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_521352_2	1232437.KL662042_gene2011	2.73e-27	106.0	COG3267@1|root,COG3267@2|Bacteria,1REWJ@1224|Proteobacteria,42Y9C@68525|delta/epsilon subdivisions,2WUJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
k59_364707_2	1463841.JOIR01000045_gene1965	5.4e-20	89.0	COG0121@1|root,COG0121@2|Bacteria,2GXCD@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4,GATase_6
k59_481833_1	189753.AXAS01000092_gene3534	1.26e-26	105.0	COG1951@1|root,COG1951@2|Bacteria,1MW8J@1224|Proteobacteria,2U0X2@28211|Alphaproteobacteria,3JX4F@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Fumarate hydratase (Fumerase)	ttdA	-	4.2.1.2,4.2.1.32	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
k59_481833_2	1123360.thalar_00557	7.09e-64	212.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2U1QF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_1227642_1	318167.Sfri_1813	1.99e-36	130.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,2Q9X9@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran
k59_1227642_2	56780.SYN_00852	9.21e-68	223.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,2MQ4F@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
k59_912355_1	429009.Adeg_0172	1.32e-31	127.0	COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,24BSX@186801|Clostridia,42HTB@68295|Thermoanaerobacterales	186801|Clostridia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k59_521398_1	429009.Adeg_1312	1.35e-15	77.4	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,42EM8@68295|Thermoanaerobacterales	186801|Clostridia	T	protein phosphatase 2C domain protein	prpC	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2,SpoIIE
k59_285965_1	1232437.KL662072_gene1774	7.39e-22	89.4	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,42QXP@68525|delta/epsilon subdivisions,2WP9I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
k59_285965_2	41431.PCC8801_3084	2.06e-10	62.4	COG0628@1|root,COG0628@2|Bacteria,1G26W@1117|Cyanobacteria,3KG14@43988|Cyanothece	1117|Cyanobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_987448_1	631362.Thi970DRAFT_03189	1.04e-46	174.0	COG4974@1|root,COG4974@2|Bacteria,1NY1A@1224|Proteobacteria,1RN33@1236|Gammaproteobacteria,1WXGD@135613|Chromatiales	135613|Chromatiales	L	PFAM transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_595387_1	426355.Mrad2831_2591	4.41e-113	338.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,2VDSQ@28211|Alphaproteobacteria,1JRF7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	TIGRFAM nitrate reductase, beta subunit	-	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
k59_751964_1	1453501.JELR01000001_gene2930	2.61e-14	79.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,466VC@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_595446_1	1116375.VEJY3_02940	8.73e-49	184.0	2EXJW@1|root,33QVY@2|Bacteria,1QSMJ@1224|Proteobacteria,1SK5H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1183318_1	765913.ThidrDRAFT_0509	1.33e-11	63.9	COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,1WWJP@135613|Chromatiales	135613|Chromatiales	S	Sterol-binding domain protein	-	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
k59_1183318_2	1283300.ATXB01000001_gene2322	2.55e-30	120.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1XDTU@135618|Methylococcales	135618|Methylococcales	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
k59_242924_1	61622.XP_010355904.1	2.6e-123	372.0	KOG0318@1|root,KOG0318@2759|Eukaryota,38FD6@33154|Opisthokonta,3BHXR@33208|Metazoa,3CVF4@33213|Bilateria,489Q6@7711|Chordata,493J3@7742|Vertebrata,3JAGD@40674|Mammalia,35INP@314146|Euarchontoglires,4MKT5@9443|Primates,35YBQ@314294|Cercopithecoidea	33208|Metazoa	Z	WD repeat domain 1	WDR1	GO:0000003,GO:0000902,GO:0000904,GO:0001667,GO:0001736,GO:0001738,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0002252,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002520,GO:0002576,GO:0003006,GO:0003008,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005856,GO:0005884,GO:0005886,GO:0005911,GO:0005938,GO:0006810,GO:0006887,GO:0006928,GO:0006996,GO:0007010,GO:0007015,GO:0007043,GO:0007163,GO:0007164,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007399,GO:0007444,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0007600,GO:0007605,GO:0008064,GO:0008092,GO:0008150,GO:0008154,GO:0008360,GO:0008544,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009913,GO:0009987,GO:0010631,GO:0010638,GO:0010639,GO:0010927,GO:0014013,GO:0014866,GO:0015629,GO:0016020,GO:0016043,GO:0016192,GO:0016333,GO:0016334,GO:0016477,GO:0016528,GO:0019953,GO:0022008,GO:0022411,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0030011,GO:0030016,GO:0030029,GO:0030030,GO:0030036,GO:0030042,GO:0030043,GO:0030054,GO:0030097,GO:0030099,GO:0030154,GO:0030182,GO:0030220,GO:0030239,GO:0030240,GO:0030707,GO:0030832,GO:0030833,GO:0030834,GO:0030836,GO:0030837,GO:0030855,GO:0030863,GO:0030864,GO:0030865,GO:0031032,GO:0031333,GO:0032271,GO:0032272,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032879,GO:0032880,GO:0032940,GO:0032956,GO:0032970,GO:0032984,GO:0032989,GO:0033043,GO:0034315,GO:0034316,GO:0034329,GO:0034330,GO:0034762,GO:0034765,GO:0035088,GO:0035090,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0035315,GO:0035316,GO:0035317,GO:0036344,GO:0040011,GO:0040012,GO:0042247,GO:0042391,GO:0042641,GO:0042643,GO:0042692,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043243,GO:0043244,GO:0043254,GO:0043269,GO:0043292,GO:0043297,GO:0043624,GO:0043933,GO:0044085,GO:0044087,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0044703,GO:0044877,GO:0045055,GO:0045197,GO:0045199,GO:0045214,GO:0045216,GO:0045595,GO:0045685,GO:0046903,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048563,GO:0048569,GO:0048609,GO:0048646,GO:0048699,GO:0048707,GO:0048713,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0048870,GO:0050767,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050900,GO:0050954,GO:0051015,GO:0051049,GO:0051125,GO:0051126,GO:0051128,GO:0051129,GO:0051130,GO:0051146,GO:0051179,GO:0051234,GO:0051239,GO:0051261,GO:0051493,GO:0051494,GO:0051495,GO:0051674,GO:0051704,GO:0051960,GO:0055001,GO:0055002,GO:0060284,GO:0060306,GO:0060307,GO:0060429,GO:0060562,GO:0061061,GO:0061245,GO:0065007,GO:0065008,GO:0070925,GO:0071689,GO:0071840,GO:0071944,GO:0090066,GO:0090130,GO:0090132,GO:0097435,GO:0097529,GO:0097530,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099568,GO:0099623,GO:0110053,GO:0120036,GO:1901879,GO:1901881,GO:1902903,GO:1902904,GO:1902905,GO:1990266,GO:2000026	-	-	-	-	-	-	-	-	-	-	WD40
k59_438502_1	414684.RC1_0800	4.91e-49	169.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,2TU50@28211|Alphaproteobacteria,2JSBB@204441|Rhodospirillales	204441|Rhodospirillales	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_438502_2	1122137.AQXF01000001_gene2819	1.99e-06	49.3	COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,2UAB1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	TonB system transport protein ExbB	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_1183327_1	1287475.HMPREF1650_10645	1.07e-15	81.6	COG1960@1|root,COG1960@2|Bacteria,2GM3V@201174|Actinobacteria,22R8T@1653|Corynebacteriaceae	201174|Actinobacteria	C	Acyl-CoA dehydrogenases	fadE6	-	1.3.8.7,1.3.8.8	ko:K00249,ko:K00255	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_517298_1	472759.Nhal_1939	8.78e-94	292.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_477816_1	9597.XP_008953570.1	1.55e-138	431.0	KOG0401@1|root,KOG0401@2759|Eukaryota,38BXU@33154|Opisthokonta,3B9GC@33208|Metazoa,3CRH4@33213|Bilateria,481TM@7711|Chordata,4979U@7742|Vertebrata,3J48A@40674|Mammalia,35NAA@314146|Euarchontoglires,4MG7C@9443|Primates,4N1CG@9604|Hominidae	33208|Metazoa	J	Domain in DAP-5, eIF4G, MA-3 and other proteins.	EIF4G1	GO:0000003,GO:0000166,GO:0000184,GO:0000280,GO:0000339,GO:0000340,GO:0000956,GO:0001558,GO:0001662,GO:0001932,GO:0001933,GO:0001934,GO:0002181,GO:0002183,GO:0002191,GO:0002209,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005198,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005844,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006996,GO:0007005,GO:0007049,GO:0007140,GO:0007154,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007346,GO:0007399,GO:0007610,GO:0008135,GO:0008144,GO:0008150,GO:0008152,GO:0008190,GO:0008283,GO:0008284,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010506,GO:0010507,GO:0010556,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0010720,GO:0010799,GO:0010801,GO:0010941,GO:0010942,GO:0016043,GO:0016070,GO:0016071,GO:0016281,GO:0017076,GO:0019219,GO:0019220,GO:0019222,GO:0019439,GO:0019538,GO:0019953,GO:0022008,GO:0022402,GO:0022412,GO:0022414,GO:0030154,GO:0030307,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031329,GO:0031330,GO:0031334,GO:0031369,GO:0031399,GO:0031400,GO:0031401,GO:0031667,GO:0031668,GO:0031669,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032947,GO:0032991,GO:0033135,GO:0033138,GO:0033555,GO:0034248,GO:0034641,GO:0034645,GO:0034655,GO:0035639,GO:0036094,GO:0040008,GO:0042127,GO:0042325,GO:0042326,GO:0042327,GO:0042592,GO:0042596,GO:0042802,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0044087,GO:0044089,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045787,GO:0045927,GO:0045931,GO:0045936,GO:0045937,GO:0046483,GO:0046700,GO:0048134,GO:0048136,GO:0048137,GO:0048232,GO:0048285,GO:0048468,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048609,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048871,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050896,GO:0051094,GO:0051098,GO:0051099,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051301,GO:0051321,GO:0051704,GO:0051716,GO:0051726,GO:0051960,GO:0051962,GO:0051963,GO:0060147,GO:0060148,GO:0060255,GO:0060284,GO:0060548,GO:0060964,GO:0060966,GO:0060968,GO:0061013,GO:0065007,GO:0065008,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090068,GO:0090304,GO:0097009,GO:0097159,GO:0097367,GO:0099174,GO:0140013,GO:1900087,GO:1901214,GO:1901215,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902415,GO:1902416,GO:1902806,GO:1902808,GO:1903046,GO:1903311,GO:1905214,GO:1905216,GO:1905535,GO:1905537,GO:1905606,GO:1905610,GO:1905612,GO:1905616,GO:1905618,GO:1905696,GO:1990904,GO:2000026,GO:2000045,GO:2000112,GO:2000637	-	ko:K03260	ko03013,ko05416,map03013,map05416	M00428	-	-	ko00000,ko00001,ko00002,ko03012,ko03019	-	-	-	MA3,MIF4G,W2
k59_125498_1	1415779.JOMH01000001_gene2885	1.77e-55	190.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1X57M@135614|Xanthomonadales	135614|Xanthomonadales	E	Sodium alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_125498_2	1217705.F900_00949	7.44e-50	172.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,3NK5Q@468|Moraxellaceae	1236|Gammaproteobacteria	I	Belongs to the thiolase family	fadI	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_164531_1	335543.Sfum_0207	1.52e-100	311.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2MR8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5	nuoL-2	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_477845_1	1265313.HRUBRA_01310	1.49e-35	132.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_477845_2	740709.A10D4_00920	5.51e-17	77.8	COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,1RRX1@1236|Gammaproteobacteria,2QFR5@267893|Idiomarinaceae	1236|Gammaproteobacteria	U	Biopolymer	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_517340_1	572477.Alvin_2766	2.77e-20	84.3	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,1S5WG@1236|Gammaproteobacteria,1WYQN@135613|Chromatiales	135613|Chromatiales	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
k59_517340_2	2340.JV46_09560	2.07e-90	283.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,1S398@1236|Gammaproteobacteria,1J6EW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	P COG0025 NhaP-type Na H and K H antiporters	-	-	-	ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37.1.2	-	-	Na_H_Exchanger
k59_712595_1	1384056.N787_03225	0.000888	46.2	COG0457@1|root,COG0457@2|Bacteria,1R8UZ@1224|Proteobacteria,1RQ7E@1236|Gammaproteobacteria,1X4WX@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
k59_712595_2	1122194.AUHU01000011_gene1665	1.48e-05	46.6	COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,1T32S@1236|Gammaproteobacteria,465Q0@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,YfiO
k59_830298_1	1121405.dsmv_1912	4.71e-31	118.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MJI4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_908651_2	1127131.WEISSC39_08860	7.38e-18	87.8	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,4AWUW@81850|Leuconostocaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
k59_1026708_1	29073.XP_008696116.1	1.63e-45	148.0	2CHT7@1|root,2S3PY@2759|Eukaryota,3A5XZ@33154|Opisthokonta,3BSJJ@33208|Metazoa,3D9DK@33213|Bilateria,48FX4@7711|Chordata,49CU4@7742|Vertebrata,3JHVV@40674|Mammalia,3EW0S@33554|Carnivora	33208|Metazoa	S	brick1, scar wave	BRK1	GO:0001701,GO:0002252,GO:0002253,GO:0002376,GO:0002429,GO:0002431,GO:0002433,GO:0002682,GO:0002684,GO:0002757,GO:0002764,GO:0002768,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0006897,GO:0006909,GO:0006928,GO:0006996,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007264,GO:0007265,GO:0007275,GO:0007399,GO:0007417,GO:0008064,GO:0008150,GO:0008284,GO:0008360,GO:0008582,GO:0009653,GO:0009790,GO:0009792,GO:0009987,GO:0010591,GO:0010592,GO:0010638,GO:0016043,GO:0016192,GO:0016601,GO:0021551,GO:0022603,GO:0022604,GO:0022607,GO:0023052,GO:0030027,GO:0030029,GO:0030036,GO:0030832,GO:0030833,GO:0030838,GO:0031209,GO:0031252,GO:0031334,GO:0031344,GO:0031346,GO:0032271,GO:0032273,GO:0032501,GO:0032502,GO:0032535,GO:0032956,GO:0032970,GO:0032991,GO:0033043,GO:0034315,GO:0035556,GO:0038093,GO:0038094,GO:0038096,GO:0040008,GO:0040011,GO:0042127,GO:0042995,GO:0043009,GO:0043254,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048010,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048638,GO:0048731,GO:0048856,GO:0048870,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050896,GO:0051125,GO:0051127,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051239,GO:0051259,GO:0051260,GO:0051489,GO:0051491,GO:0051493,GO:0051495,GO:0051674,GO:0051716,GO:0051960,GO:0051963,GO:0060491,GO:0065003,GO:0065007,GO:0065008,GO:0070206,GO:0070207,GO:0071840,GO:0090066,GO:0098657,GO:0110053,GO:0120025,GO:0120032,GO:0120034,GO:0120035,GO:1902743,GO:1902745,GO:1902903,GO:1902905,GO:1904396,GO:2000026,GO:2000601	-	ko:K05752	ko04810,map04810	-	-	-	ko00000,ko00001	-	-	-	-
k59_281906_1	1150474.JQJI01000016_gene543	4.09e-19	88.2	COG2810@1|root,COG2810@2|Bacteria,2GDMR@200918|Thermotogae	200918|Thermotogae	V	SeqA protein C-terminal domain	-	-	-	ko:K07504	-	-	-	-	ko00000	-	-	-	-
k59_1104985_1	1479237.JMLY01000001_gene895	1.59e-81	251.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S726@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k59_321072_2	247633.GP2143_07954	8.14e-33	121.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,1SD41@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
k59_243072_1	314278.NB231_11694	5.02e-109	336.0	COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,1S118@1236|Gammaproteobacteria,1X0F2@135613|Chromatiales	135613|Chromatiales	I	Squalene-hopene cyclase N-terminal domain	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
k59_7935_1	765914.ThisiDRAFT_0479	1.26e-40	142.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1WW6P@135613|Chromatiales	135613|Chromatiales	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PRAI
k59_7935_2	1249627.D779_4081	2.19e-39	136.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,1WX4R@135613|Chromatiales	135613|Chromatiales	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
k59_830389_1	1123024.AUII01000001_gene3114	7.77e-14	76.3	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2101	PPDK_N
k59_595618_1	1461694.ATO9_10665	1.08e-78	243.0	28KEA@1|root,2ZA0J@2|Bacteria,1R5TS@1224|Proteobacteria,2U48U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Sulfotransferase domain	-	-	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
k59_673883_1	643648.Slip_1196	2.32e-129	377.0	COG1788@1|root,COG1788@2|Bacteria,1UYH2@1239|Firmicutes,24CPB@186801|Clostridia	186801|Clostridia	I	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_203487_1	335543.Sfum_3313	3.39e-39	140.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,2MQEZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_673886_1	686340.Metal_1907	7.56e-41	145.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XDY1@135618|Methylococcales	135618|Methylococcales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_402499_1	555779.Dthio_PD3188	5.04e-110	335.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,431TI@68525|delta/epsilon subdivisions,2WWAP@28221|Deltaproteobacteria,2MB98@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc,DUF4338
k59_363299_1	879212.DespoDRAFT_01024	1.27e-108	334.0	COG1578@1|root,COG1578@2|Bacteria,1R50K@1224|Proteobacteria,42Q0S@68525|delta/epsilon subdivisions,2WJ5M@28221|Deltaproteobacteria,2MIQ5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF89	-	-	-	-	-	-	-	-	-	-	-	-	DUF89
k59_990832_1	1121405.dsmv_0501	5.05e-33	125.0	COG1903@1|root,COG1903@2|Bacteria,1MXU3@1224|Proteobacteria,42N2R@68525|delta/epsilon subdivisions,2WJF4@28221|Deltaproteobacteria,2MI6Z@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
k59_598222_1	1038860.AXAP01000166_gene314	7.09e-67	214.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,3JVIU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_127863_1	933262.AXAM01000010_gene1377	1.88e-16	80.5	COG1680@1|root,COG1680@2|Bacteria,1QUYZ@1224|Proteobacteria,42PUC@68525|delta/epsilon subdivisions,2WK0V@28221|Deltaproteobacteria,2MIWD@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_127863_2	1122138.AQUZ01000036_gene5457	1.15e-22	96.3	COG1619@1|root,COG1619@2|Bacteria,2I358@201174|Actinobacteria,4DUAP@85009|Propionibacteriales	201174|Actinobacteria	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
k59_166994_1	1283287.KB822576_gene3806	1.28e-05	52.8	COG3568@1|root,COG3568@2|Bacteria,2GP3V@201174|Actinobacteria	201174|Actinobacteria	L	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_519931_1	933262.AXAM01000109_gene2063	1.88e-96	308.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria,2MI1M@213118|Desulfobacterales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1185940_1	1121405.dsmv_2329	5.42e-63	208.0	COG5000@1|root,COG5000@2|Bacteria,1QWMS@1224|Proteobacteria,43BSR@68525|delta/epsilon subdivisions,2X73I@28221|Deltaproteobacteria,2MPJM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_89395_1	545264.KB898757_gene2483	1.03e-10	60.8	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1WXFY@135613|Chromatiales	135613|Chromatiales	G	Glycosyltransferase 36 associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
k59_1107496_1	118797.XP_007464583.1	7.36e-188	521.0	COG0090@1|root,KOG2309@2759|Eukaryota,38BCB@33154|Opisthokonta,3BGMC@33208|Metazoa,3CS9I@33213|Bilateria,488FY@7711|Chordata,493M2@7742|Vertebrata,3JECN@40674|Mammalia,4IZZ1@91561|Cetartiodactyla	33208|Metazoa	J	ribosomal protein L8	RPL8	GO:0000184,GO:0000956,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009719,GO:0009892,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015934,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0042221,GO:0042788,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0070727,GO:0070848,GO:0070887,GO:0070972,GO:0071310,GO:0071363,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990089,GO:1990090,GO:1990904,GO:1990932	-	ko:K02938	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_872079_2	314231.FP2506_06111	1.43e-63	200.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2TRUT@28211|Alphaproteobacteria,2PJIJ@255475|Aurantimonadaceae	28211|Alphaproteobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_441342_1	745014.OMB55_00024490	3.08e-75	232.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1J4ZD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355	Ubie_methyltran
k59_754652_1	1267005.KB911259_gene3707	6.9e-112	353.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria,3N67W@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
k59_990935_1	1304872.JAGC01000003_gene2307	3.7e-15	81.3	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2M7Z5@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Cache_3-Cache_2,HAMP,SpoIIE,dCache_1,dCache_2
k59_480561_1	42256.RradSPS_2889	3.14e-49	165.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4CSYC@84995|Rubrobacteria	84995|Rubrobacteria	K	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Rhodanese
k59_520045_2	195103.CPF_2957	1.56e-08	57.8	COG1051@1|root,COG1051@2|Bacteria,1V5NQ@1239|Firmicutes,24PPQ@186801|Clostridia,36KMQ@31979|Clostridiaceae	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
k59_1068113_1	1123240.ATVO01000006_gene1661	3.22e-42	158.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2K25R@204457|Sphingomonadales	204457|Sphingomonadales	C	aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_10409_1	1121405.dsmv_0616	6.23e-104	323.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,42NNE@68525|delta/epsilon subdivisions,2WJZX@28221|Deltaproteobacteria,2MI6X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	qmoB	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_9,FlpD,Pyr_redox_2
k59_402727_1	1161401.ASJA01000033_gene3049	3.92e-75	238.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,43WYN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_480616_1	1267005.KB911260_gene3576	7.83e-56	179.0	COG5349@1|root,COG5349@2|Bacteria,1MZDD@1224|Proteobacteria,2UCM4@28211|Alphaproteobacteria,3N74I@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
k59_793810_1	1121405.dsmv_0381	2.3e-69	226.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WJY2@28221|Deltaproteobacteria,2MHX0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_363498_1	880072.Desac_2529	3.86e-83	254.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria,2MQBF@213462|Syntrophobacterales	28221|Deltaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_793814_1	1304885.AUEY01000036_gene2247	1.05e-96	299.0	COG0591@1|root,COG0591@2|Bacteria,1PNHU@1224|Proteobacteria,43AQ2@68525|delta/epsilon subdivisions,2X63U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_793836_1	631362.Thi970DRAFT_02046	1.22e-75	238.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1WWJJ@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_10464_1	246200.SPO0479	5.53e-54	181.0	COG3676@1|root,COG3677@1|root,COG3676@2|Bacteria,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,4NDP6@97050|Ruegeria	28211|Alphaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_10464_2	1120983.KB894574_gene1005	2.35e-14	75.9	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,1JPHB@119043|Rhodobiaceae	28211|Alphaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_558953_1	745014.OMB55_00010900	1.45e-20	85.5	COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,1SAVX@1236|Gammaproteobacteria,1JB9W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
k59_558953_2	1333998.M2A_1262	6.28e-49	161.0	COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,2U66N@28211|Alphaproteobacteria,4BSEJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
k59_598456_1	414684.RC1_2114	4.54e-103	313.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,2TSTQ@28211|Alphaproteobacteria,2JQT8@204441|Rhodospirillales	204441|Rhodospirillales	C	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex	bchB	-	1.3.7.7	ko:K04039	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06282	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro,PCP_red
k59_441526_1	1071073.KI530536_gene1031	9.57e-20	85.9	COG1794@1|root,COG1794@2|Bacteria,1TR3U@1239|Firmicutes,4HCAN@91061|Bacilli,1ZDW9@1386|Bacillus	91061|Bacilli	M	Belongs to the aspartate glutamate racemases family	racD	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
k59_441526_2	1121926.AXWO01000029_gene4400	9.73e-23	94.7	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4EXQE@85014|Glycomycetales	201174|Actinobacteria	L	FES	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
k59_1068192_1	243164.DET1003	1.72e-28	112.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi,34CZI@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
k59_402828_1	83406.HDN1F_31540	1.39e-22	104.0	28HYC@1|root,2Z83T@2|Bacteria,1QEBM@1224|Proteobacteria,1RRCK@1236|Gammaproteobacteria,1J5NU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1198461_1	1380394.JADL01000004_gene6068	5.76e-80	254.0	COG0747@1|root,COG0747@2|Bacteria,1MWBH@1224|Proteobacteria,2TTF4@28211|Alphaproteobacteria,2JV79@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_61247_1	646529.Desaci_3791	2.26e-55	187.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,260DU@186807|Peptococcaceae	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
k59_493157_1	58344.JOEL01000012_gene2544	7.2e-17	80.1	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_179614_2	1123399.AQVE01000004_gene2554	4.33e-24	100.0	COG3391@1|root,COG3391@2|Bacteria,1MXDX@1224|Proteobacteria,1S012@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
k59_102259_1	869210.Marky_1642	1.25e-120	357.0	COG3033@1|root,COG3033@2|Bacteria,1WM62@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_220867_1	318167.Sfri_0030	3.11e-89	270.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,2QA4X@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760	Coprogen_oxidas
k59_963578_1	1210884.HG799463_gene9989	2.5e-17	81.3	COG1595@1|root,COG1595@2|Bacteria,2IZXS@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_611066_1	9606.ENSP00000366156	9.25e-171	479.0	COG0421@1|root,KOG1562@2759|Eukaryota,39J87@33154|Opisthokonta,3BCX8@33208|Metazoa,3D093@33213|Bilateria,4873X@7711|Chordata,48XN6@7742|Vertebrata,3JCNW@40674|Mammalia,35GV8@314146|Euarchontoglires,4MFBE@9443|Primates,4N4HM@9604|Hominidae	33208|Metazoa	H	Spermidine synthase tetramerisation domain	SRM	GO:0003674,GO:0003824,GO:0004766,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010033,GO:0016740,GO:0016765,GO:0034097,GO:0034641,GO:0042221,GO:0042401,GO:0042802,GO:0042803,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071345,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576,GO:1990823,GO:1990830	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
k59_1198492_1	118797.XP_007460799.1	4.8e-117	353.0	KOG1676@1|root,KOG1676@2759|Eukaryota,38H75@33154|Opisthokonta,3BHJ2@33208|Metazoa,3CTFY@33213|Bilateria,4872V@7711|Chordata,492GI@7742|Vertebrata,3JEY4@40674|Mammalia,4IWJ5@91561|Cetartiodactyla	33208|Metazoa	A	KH-type splicing regulatory protein	KHSRP	GO:0000003,GO:0000375,GO:0000381,GO:0001505,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006397,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0007276,GO:0007283,GO:0008150,GO:0008152,GO:0008380,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010494,GO:0010556,GO:0010558,GO:0010586,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0010984,GO:0010985,GO:0010988,GO:0010989,GO:0016070,GO:0016071,GO:0017091,GO:0017148,GO:0019219,GO:0019222,GO:0019439,GO:0019953,GO:0022414,GO:0030425,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031329,GO:0031331,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032501,GO:0032504,GO:0032991,GO:0033119,GO:0034097,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0034660,GO:0035770,GO:0035925,GO:0036464,GO:0036477,GO:0042221,GO:0042995,GO:0043005,GO:0043025,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043484,GO:0043487,GO:0043488,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044703,GO:0045019,GO:0045428,GO:0045934,GO:0045935,GO:0046483,GO:0046700,GO:0048024,GO:0048025,GO:0048232,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048609,GO:0050684,GO:0050686,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0051716,GO:0060255,GO:0061013,GO:0061014,GO:0061157,GO:0061158,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071310,GO:0071345,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097447,GO:0097458,GO:0120025,GO:0120038,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1903311,GO:1903312,GO:1903313,GO:1903426,GO:1903427,GO:1904406,GO:1990904,GO:2000112,GO:2000113,GO:2000377,GO:2000378,GO:2000628	-	ko:K13210	-	-	-	-	ko00000,ko03019,ko03041	-	-	-	DUF1897,KH_1
k59_689142_2	911045.PSE_4152	1.18e-16	79.3	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2TQQC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_963590_2	1430440.MGMSRv2_1070	5.67e-97	295.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2U2F7@28211|Alphaproteobacteria,2JPK6@204441|Rhodospirillales	204441|Rhodospirillales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_139867_1	1443665.JACA01000019_gene4872	7.5e-10	65.1	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,4PKDT@976|Bacteroidetes,1IJ8G@117743|Flavobacteriia,2YIJK@290174|Aquimarina	976|Bacteroidetes	DZ	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
k59_220910_1	1121405.dsmv_0065	5.14e-73	224.0	COG2203@1|root,COG2203@2|Bacteria,1NBYK@1224|Proteobacteria,42NFX@68525|delta/epsilon subdivisions,2WM8H@28221|Deltaproteobacteria,2MIRU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM GAF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2
k59_453704_1	247639.MGP2080_14324	4.53e-09	56.2	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1J5XB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins	iscR	GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
k59_453704_2	1286106.MPL1_09467	1.55e-29	116.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,4609D@72273|Thiotrichales	72273|Thiotrichales	E	Cysteine desulfurase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_649240_1	794846.AJQU01000062_gene2593	3.76e-114	333.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,4BA62@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	MA20_17020	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
k59_805415_1	265072.Mfla_1476	4.71e-104	315.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria,2KKZ1@206350|Nitrosomonadales	206350|Nitrosomonadales	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
k59_378907_1	748280.NH8B_3123	1.25e-54	191.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,2KPRE@206351|Neisseriales	206351|Neisseriales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_651757_1	1269813.ATUL01000008_gene1560	5.28e-94	297.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1WWYF@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_339132_1	1345023.M467_15705	2.17e-17	81.6	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_573991_1	756067.MicvaDRAFT_4048	1.86e-52	183.0	COG2208@1|root,COG3850@1|root,COG2208@2|Bacteria,COG3850@2|Bacteria,1G3MK@1117|Cyanobacteria,1H9X2@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Sporulation stage II, protein E C-terminal	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HAMP,HisKA,Response_reg,SpoIIE
k59_613621_1	203122.Sde_4009	5.1e-61	197.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,4649M@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_691820_1	326297.Sama_0227	1.44e-51	166.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,2QBN5@267890|Shewanellaceae	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_691820_2	28258.KP05_11920	6e-42	139.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1XKDP@135619|Oceanospirillales	135619|Oceanospirillales	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_1201296_1	743836.AYNA01000130_gene1417	4.06e-42	150.0	COG0791@1|root,COG0791@2|Bacteria,1MW03@1224|Proteobacteria,2TSFG@28211|Alphaproteobacteria,36Y8W@31993|Methylocystaceae	28211|Alphaproteobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
k59_105381_1	1232437.KL662031_gene2613	5.49e-44	154.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,2MI98@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_142528_1	1121441.AUCX01000032_gene3179	2.63e-46	170.0	COG0503@1|root,COG0827@1|root,COG0503@2|Bacteria,COG0827@2|Bacteria,1QZ6D@1224|Proteobacteria,42Z8W@68525|delta/epsilon subdivisions,2WU49@28221|Deltaproteobacteria,2MAY9@213115|Desulfovibrionales	28221|Deltaproteobacteria	LMNU	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	MTS
k59_378986_1	1380394.JADL01000001_gene3072	7.68e-59	193.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2TR20@28211|Alphaproteobacteria,2JPF7@204441|Rhodospirillales	204441|Rhodospirillales	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
k59_848353_1	523791.Kkor_1103	3.03e-76	244.0	COG0644@1|root,COG0644@2|Bacteria,1R41S@1224|Proteobacteria,1SME7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Tryptophan halogenase	-	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
k59_1046376_1	396588.Tgr7_2193	4.94e-83	263.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1WWDT@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2
k59_182041_1	698440.XP_007290556.1	1.04e-39	151.0	COG0133@1|root,COG0159@1|root,KOG1395@2759|Eukaryota,KOG4175@2759|Eukaryota,38GS5@33154|Opisthokonta,3NUJ5@4751|Fungi,3QJDI@4890|Ascomycota,20VG0@147548|Leotiomycetes	4751|Fungi	E	Tryptophan synthase alpha chain	-	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01694	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R02722	RC00210,RC00700,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Trp_syntA
k59_224208_1	177437.HRM2_27500	2.28e-25	99.8	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2WQGH@28221|Deltaproteobacteria,2MJJ6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_691852_1	879212.DespoDRAFT_02008	6.23e-78	239.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2MI23@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
k59_423078_2	1415778.JQMM01000001_gene1413	3.64e-97	285.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1J4EN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_887735_1	511062.GU3_04160	8.69e-31	119.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1Y3JI@135624|Aeromonadales	135624|Aeromonadales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_887735_2	759914.BP951000_1603	7.06e-08	55.8	COG1544@1|root,COG1544@2|Bacteria	2|Bacteria	J	regulation of translation	raiA	-	-	ko:K03733,ko:K05808,ko:K05809	-	-	-	-	ko00000,ko03009,ko03036	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
k59_691862_1	1499967.BAYZ01000006_gene5459	2.01e-88	273.0	COG0444@1|root,COG0444@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_495951_1	983545.Glaag_0001	2.7e-54	183.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,46444@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_495951_2	1411685.U062_01436	6.16e-27	108.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1J4Z6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_769895_1	1298863.AUEP01000014_gene1712	2.13e-81	266.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4DPP4@85009|Propionibacteriales	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_25152_2	439235.Dalk_5059	2.08e-16	80.9	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2MHWG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_1122904_1	765912.Thimo_0512	1.75e-18	87.8	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1WX1P@135613|Chromatiales	135613|Chromatiales	S	Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
k59_807943_1	1385515.N791_14065	2.44e-31	123.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1X3IQ@135614|Xanthomonadales	135614|Xanthomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_887762_1	1380394.JADL01000002_gene1408	2.73e-18	83.2	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,2JPIQ@204441|Rhodospirillales	28211|Alphaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_887762_2	1267005.KB911256_gene2042	1.05e-48	156.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,3N72T@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_495974_1	335543.Sfum_2527	4.99e-90	288.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2MQ85@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_25171_1	439235.Dalk_2273	4.93e-17	84.3	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria,2MIJ9@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
k59_887771_1	1120956.JHZK01000001_gene3467	1.03e-90	273.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2TQKB@28211|Alphaproteobacteria,1JMYX@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	-	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Succ_CoA_lig
k59_105494_1	335543.Sfum_0536	2.84e-69	217.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2MQEG@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	TIGRFAM signal peptidase I	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
k59_379072_1	1121405.dsmv_3030	2.82e-84	258.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,2MN4X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
k59_613743_1	1120985.AUMI01000011_gene115	3e-15	75.9	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,4H2XK@909932|Negativicutes	909932|Negativicutes	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
k59_691924_1	1410676.JNKL01000032_gene1666	2.76e-49	167.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1Y3N0@135624|Aeromonadales	135624|Aeromonadales	U	MotA/TolQ/ExbB proton channel family	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k59_456541_2	1469245.JFBG01000023_gene1276	1.91e-98	297.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
k59_64089_2	933262.AXAM01000005_gene2497	1.2e-43	149.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,42N3R@68525|delta/epsilon subdivisions,2WJDN@28221|Deltaproteobacteria,2MIW5@213118|Desulfobacterales	28221|Deltaproteobacteria	N	flagellar basal-body rod protein FlgG	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
k59_423193_1	1444309.JAQG01000075_gene140	5.2e-64	206.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,26RBP@186822|Paenibacillaceae	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_379122_1	1158182.KB905031_gene2455	1.13e-67	223.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1WXED@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_730821_1	876044.IMCC3088_635	1.05e-110	329.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1MWNX@1224|Proteobacteria,1RQHG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,LZ_Tnp_IS481,rve
k59_105547_1	519989.ECTPHS_10124	6.07e-80	261.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1WWP6@135613|Chromatiales	135613|Chromatiales	D	DNA segregation ATPase FtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_574154_1	1380367.JIBC01000015_gene43	2.4e-18	85.1	COG2358@1|root,COG2358@2|Bacteria,1NSZ5@1224|Proteobacteria,2U3NZ@28211|Alphaproteobacteria,3ZW4C@60136|Sulfitobacter	28211|Alphaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_651907_1	1384056.N787_12995	7.84e-38	128.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1X7EI@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_339311_1	293826.Amet_3160	3.78e-47	169.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E82@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
k59_379158_1	96561.Dole_3224	8.12e-69	215.0	COG1392@1|root,COG1392@2|Bacteria,1N4VJ@1224|Proteobacteria,42RQQ@68525|delta/epsilon subdivisions,2WNV1@28221|Deltaproteobacteria,2MM6Z@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
k59_574177_1	1112214.AHIS01000027_gene1030	8.06e-75	251.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria,2JZWE@204457|Sphingomonadales	204457|Sphingomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1161984_1	1121918.ARWE01000001_gene257	2.96e-29	112.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2WIMS@28221|Deltaproteobacteria,43TEZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_64136_1	272568.GDI2240	9.04e-31	123.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,2TTFW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the peptidase M50B family	-	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CBS,Peptidase_M50
k59_848489_1	1479238.JQMZ01000001_gene1934	5.37e-36	133.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2TSWA@28211|Alphaproteobacteria,43X9C@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_300708_1	61853.ENSNLEP00000006643	1.43e-136	387.0	KOG3466@1|root,KOG3466@2759|Eukaryota,39SZ6@33154|Opisthokonta,3BIGK@33208|Metazoa,3CYZX@33213|Bilateria,48986@7711|Chordata,48YQR@7742|Vertebrata,3JCY3@40674|Mammalia,35FAK@314146|Euarchontoglires,4M8EP@9443|Primates	33208|Metazoa	C	NADH dehydrogenase (ubiquinone) 1 beta subcomplex	NDUFB9	GO:0003008,GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007600,GO:0007605,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010257,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0050877,GO:0050954,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	-	ko:K03965	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00147	-	-	ko00000,ko00001,ko00002	3.D.1.6	-	-	Complex1_LYR,Complex1_LYR_2
k59_966619_1	1232437.KL661988_gene233	3.67e-75	232.0	COG0489@1|root,COG0489@2|Bacteria,1R6AC@1224|Proteobacteria,42NTJ@68525|delta/epsilon subdivisions,2WM95@28221|Deltaproteobacteria,2MJ5Z@213118|Desulfobacterales	28221|Deltaproteobacteria	D	protein tyrosine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_379210_1	648757.Rvan_3076	6.1e-89	268.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2TU64@28211|Alphaproteobacteria,3N6MJ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
k59_1179432_1	1122939.ATUD01000003_gene3373	6.25e-45	161.0	COG1903@1|root,COG1903@2|Bacteria,2GM41@201174|Actinobacteria,4CPGG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
k59_199705_1	1388763.O165_018630	8.56e-12	68.2	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria,1YY40@136845|Pseudomonas putida group	1236|Gammaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k59_82378_1	378806.STAUR_3100	1.75e-44	157.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Y93@68525|delta/epsilon subdivisions,2WU1Y@28221|Deltaproteobacteria,2YTTS@29|Myxococcales	28221|Deltaproteobacteria	H	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_633854_1	7245.FBpp0255477	3.27e-48	161.0	COG0317@1|root,KOG1157@2759|Eukaryota,39Y6C@33154|Opisthokonta,3BNBB@33208|Metazoa,3CWZI@33213|Bilateria,41YRQ@6656|Arthropoda,3SMN5@50557|Insecta,453I9@7147|Diptera,45TPZ@7214|Drosophilidae	33208|Metazoa	T	HD domain	HDDC3	GO:0003674,GO:0003824,GO:0006139,GO:0006152,GO:0006163,GO:0006195,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008893,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009154,GO:0009164,GO:0009166,GO:0009259,GO:0009261,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0015971,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0031667,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034035,GO:0034037,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046128,GO:0046130,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.7.2	ko:K21138	ko00230,map00230	-	R00336	RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
k59_946908_3	314278.NB231_11879	9.96e-16	77.4	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WW4B@135613|Chromatiales	135613|Chromatiales	T	response regulator	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Sigma54_activat
k59_1064603_1	9606.ENSP00000296255	1.68e-132	391.0	KOG2291@1|root,KOG2291@2759|Eukaryota,38DP8@33154|Opisthokonta,3BABJ@33208|Metazoa,3CX18@33213|Bilateria,47ZPN@7711|Chordata,48WHN@7742|Vertebrata,3J428@40674|Mammalia,35E9A@314146|Euarchontoglires,4MAEJ@9443|Primates,4MUG3@9604|Hominidae	33208|Metazoa	O	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	RPN1	GO:0003674,GO:0003824,GO:0004576,GO:0004579,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005791,GO:0005829,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008250,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0012505,GO:0015833,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0031410,GO:0031982,GO:0031984,GO:0032991,GO:0034645,GO:0036211,GO:0042175,GO:0042470,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048770,GO:0051179,GO:0051234,GO:0070085,GO:0071702,GO:0071704,GO:0071705,GO:0097708,GO:0098796,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990234	-	ko:K12666	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	-	-	ko00000,ko00001,ko00002	-	-	-	Ribophorin_I
k59_6915_1	439235.Dalk_2557	3.37e-94	299.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MIGI@213118|Desulfobacterales	68525|delta/epsilon subdivisions	C	PFAM molybdopterin oxidoreductase	nuoG-1	-	1.17.1.10,1.6.5.3	ko:K00336,ko:K05299	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3349	Fer2_4,Fer4,Fer4_10,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_1025682_2	1163409.UUA_09431	7.94e-35	130.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1X39G@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
k59_986591_1	479434.Sthe_2375	2.02e-40	147.0	COG3214@1|root,COG3214@2|Bacteria,2GA5Q@200795|Chloroflexi,27ZBY@189775|Thermomicrobia	189775|Thermomicrobia	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
k59_163521_1	880072.Desac_1833	8.37e-07	50.8	COG3640@1|root,COG3640@2|Bacteria,1RB02@1224|Proteobacteria,42NBP@68525|delta/epsilon subdivisions,2WKS7@28221|Deltaproteobacteria,2MQCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
k59_163521_2	335543.Sfum_4100	2.53e-87	264.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,42N4U@68525|delta/epsilon subdivisions,2WJR7@28221|Deltaproteobacteria,2MQ3Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k59_437555_2	382464.ABSI01000005_gene1406	4.47e-08	58.5	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	Apolipoprotein,VWA_2,YadA_anchor
k59_1103885_1	264203.ZMO0362	2.88e-35	134.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,2K0F9@204457|Sphingomonadales	204457|Sphingomonadales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_516336_1	375286.mma_1631	3.8e-30	118.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,473XK@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_516336_2	1211114.ALIP01000091_gene2876	5.42e-94	278.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,1X3EF@135614|Xanthomonadales	135614|Xanthomonadales	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_1142850_1	335543.Sfum_1711	1.11e-33	126.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,2MQ9T@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_829364_1	96561.Dole_2261	1.2e-21	95.9	COG0607@1|root,COG1633@1|root,COG0607@2|Bacteria,COG1633@2|Bacteria,1MZPW@1224|Proteobacteria,42NX5@68525|delta/epsilon subdivisions,2WMJ4@28221|Deltaproteobacteria,2MJ8M@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rubrerythrin
k59_359825_1	1121405.dsmv_1068	4.46e-107	315.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,42NK5@68525|delta/epsilon subdivisions,2WJ49@28221|Deltaproteobacteria,2MJA7@213118|Desulfobacterales	28221|Deltaproteobacteria	H	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
k59_1103918_1	1267533.KB906733_gene2879	5.19e-72	231.0	COG0427@1|root,COG0427@2|Bacteria,3Y3BI@57723|Acidobacteria,2JKXB@204432|Acidobacteriia	204432|Acidobacteriia	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
k59_359840_1	1121405.dsmv_1967	1.68e-87	276.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MMTC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K05587,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k59_947014_1	690850.Desaf_2573	2.58e-130	382.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,42Q8I@68525|delta/epsilon subdivisions,2X5IX@28221|Deltaproteobacteria,2MA7R@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_241953_1	994573.T472_0215450	1.21e-45	167.0	29DE2@1|root,300BX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_868544_1	745014.OMB55_00012560	3.72e-59	195.0	COG2130@1|root,COG2130@2|Bacteria,1MUR0@1224|Proteobacteria,1RYTZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2855)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2855
k59_1221507_1	1267005.KB911266_gene1250	3.4e-93	283.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,3N7U4@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_163648_2	2340.JV46_16340	2.63e-89	288.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1J4YE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_790417_1	1245475.ANAE01000147_gene176	5.83e-06	47.8	COG0318@1|root,COG0318@2|Bacteria,2IEND@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_790417_2	693977.Deipr_2549	8.27e-56	189.0	COG2370@1|root,COG2370@2|Bacteria,1WMVK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k59_555330_1	394.NGR_c19600	2.48e-73	246.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,4B8TD@82115|Rhizobiaceae	28211|Alphaproteobacteria	V	efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_320125_1	264203.ZMO0935	4.68e-58	187.0	COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,2U8NX@28211|Alphaproteobacteria,2KD14@204457|Sphingomonadales	204457|Sphingomonadales	H	PFAM Glutathione S-transferase domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N_3
k59_986736_1	1265505.ATUG01000002_gene1414	1.22e-73	231.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,42RSB@68525|delta/epsilon subdivisions,2X6V6@28221|Deltaproteobacteria,2MMG6@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
k59_1221538_1	420324.KI911965_gene528	6.63e-63	217.0	COG0642@1|root,COG2199@1|root,COG4192@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,COG4192@2|Bacteria,1NRP8@1224|Proteobacteria,2TXMN@28211|Alphaproteobacteria,1JQWM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
k59_320164_1	1163617.SCD_n02349	6.63e-45	154.0	COG0526@1|root,COG1413@1|root,COG0526@2|Bacteria,COG1413@2|Bacteria,1RHTS@1224|Proteobacteria,2VTRR@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Thioredoxin_3
k59_320164_2	768671.ThimaDRAFT_1996	8.57e-34	118.0	2EANF@1|root,334QY@2|Bacteria,1N8X0@1224|Proteobacteria,1SCTI@1236|Gammaproteobacteria,1WYZB@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_672970_1	1265505.ATUG01000002_gene2316	2.71e-44	144.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,2MKMM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
k59_672970_2	1121405.dsmv_3221	1.71e-37	135.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2WIM4@28221|Deltaproteobacteria,2MI7D@213118|Desulfobacterales	28221|Deltaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
k59_986789_1	709797.CSIRO_2523	6.33e-34	132.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2TW3X@28211|Alphaproteobacteria,3K6S8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_8,PAS_9,Sigma54_activat
k59_399039_1	864069.MicloDRAFT_00048880	2.49e-48	162.0	COG2716@1|root,COG2716@2|Bacteria,1RM4T@1224|Proteobacteria,2UBAI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	regulation of RNA biosynthetic process	-	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
k59_399039_2	498211.CJA_0768	9.85e-26	103.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1FGU2@10|Cellvibrio	1236|Gammaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_85831_1	744985.HIMB59_00009930	1.59e-87	283.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria,4BPQG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Formate dehydrogenase, alpha subunit	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_399043_1	1397528.Q671_12880	6.56e-62	199.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales	135619|Oceanospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_7132_2	29073.XP_008682850.1	3.88e-63	203.0	COG0057@1|root,COG5126@1|root,KOG0027@2759|Eukaryota,KOG0657@2759|Eukaryota,38ETU@33154|Opisthokonta,3BAEQ@33208|Metazoa,3CUJJ@33213|Bilateria,481VF@7711|Chordata,48WHI@7742|Vertebrata,3JBHU@40674|Mammalia,3EMTW@33554|Carnivora	33208|Metazoa	T	Calmodulin	CALM3	-	-	ko:K02183	ko04014,ko04015,ko04016,ko04020,ko04022,ko04024,ko04070,ko04114,ko04218,ko04261,ko04270,ko04371,ko04626,ko04713,ko04720,ko04722,ko04728,ko04740,ko04744,ko04745,ko04750,ko04910,ko04912,ko04915,ko04916,ko04921,ko04922,ko04924,ko04925,ko04970,ko04971,ko05010,ko05031,ko05034,ko05133,ko05152,ko05167,ko05200,ko05214,ko05418,map04014,map04015,map04016,map04020,map04022,map04024,map04070,map04114,map04218,map04261,map04270,map04371,map04626,map04713,map04720,map04722,map04728,map04740,map04744,map04745,map04750,map04910,map04912,map04915,map04916,map04921,map04922,map04924,map04925,map04970,map04971,map05010,map05031,map05034,map05133,map05152,map05167,map05200,map05214,map05418	-	-	-	ko00000,ko00001,ko01009,ko03036,ko04131,ko04147	-	-	-	EF-hand_1
k59_202571_1	1304885.AUEY01000036_gene2247	1.47e-88	278.0	COG0591@1|root,COG0591@2|Bacteria,1PNHU@1224|Proteobacteria,43AQ2@68525|delta/epsilon subdivisions,2X63U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_124709_1	384765.SIAM614_02581	4.52e-62	206.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_594668_1	1122194.AUHU01000003_gene2391	3.08e-95	291.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,1RRH7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_281139_1	1150599.MPHLEI_07769	1.12e-10	67.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,2370G@1762|Mycobacteriaceae	201174|Actinobacteria	S	amidohydrolase	nfdA_1	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_320191_1	27679.XP_003923627.1	0.0	1229.0	COG0443@1|root,KOG0101@2759|Eukaryota,38BSZ@33154|Opisthokonta,3BA18@33208|Metazoa,3CWU8@33213|Bilateria,48265@7711|Chordata,48W7U@7742|Vertebrata,3J3QJ@40674|Mammalia,35D48@314146|Euarchontoglires,4ME1V@9443|Primates	33208|Metazoa	O	RNA splicing	HSPA8	GO:0000166,GO:0000323,GO:0000375,GO:0000377,GO:0000398,GO:0000974,GO:0001664,GO:0001775,GO:0001786,GO:0001910,GO:0001912,GO:0001914,GO:0001916,GO:0001917,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002703,GO:0002705,GO:0002706,GO:0002708,GO:0002709,GO:0002711,GO:0002819,GO:0002821,GO:0002822,GO:0002824,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005102,GO:0005488,GO:0005504,GO:0005515,GO:0005524,GO:0005543,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005764,GO:0005765,GO:0005768,GO:0005770,GO:0005773,GO:0005774,GO:0005775,GO:0005776,GO:0005829,GO:0005856,GO:0005874,GO:0005882,GO:0005886,GO:0006139,GO:0006163,GO:0006355,GO:0006396,GO:0006397,GO:0006457,GO:0006458,GO:0006464,GO:0006468,GO:0006518,GO:0006605,GO:0006606,GO:0006622,GO:0006623,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006887,GO:0006913,GO:0006914,GO:0006950,GO:0006955,GO:0006986,GO:0006996,GO:0007033,GO:0007034,GO:0007040,GO:0007041,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007369,GO:0008021,GO:0008104,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008289,GO:0008380,GO:0009056,GO:0009057,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009267,GO:0009605,GO:0009611,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009894,GO:0009966,GO:0009986,GO:0009987,GO:0009991,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010656,GO:0010660,GO:0010662,GO:0010664,GO:0010665,GO:0010667,GO:0010941,GO:0012505,GO:0012506,GO:0014069,GO:0015031,GO:0015630,GO:0015833,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0016192,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017038,GO:0017076,GO:0017111,GO:0017144,GO:0019219,GO:0019221,GO:0019222,GO:0019538,GO:0019637,GO:0019693,GO:0019899,GO:0019904,GO:0022411,GO:0023051,GO:0023052,GO:0030100,GO:0030133,GO:0030135,GO:0030136,GO:0030141,GO:0030162,GO:0030163,GO:0030424,GO:0030425,GO:0030554,GO:0030659,GO:0030662,GO:0030665,GO:0030674,GO:0031072,GO:0031090,GO:0031099,GO:0031101,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031406,GO:0031410,GO:0031625,GO:0031647,GO:0031667,GO:0031668,GO:0031669,GO:0031685,GO:0031686,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032268,GO:0032270,GO:0032279,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032940,GO:0032984,GO:0032991,GO:0033036,GO:0033120,GO:0033218,GO:0033267,GO:0033293,GO:0033365,GO:0033554,GO:0034097,GO:0034504,GO:0034613,GO:0034641,GO:0034774,GO:0035639,GO:0035821,GO:0035966,GO:0036010,GO:0036094,GO:0036211,GO:0036230,GO:0036477,GO:0040007,GO:0040036,GO:0042026,GO:0042060,GO:0042119,GO:0042221,GO:0042246,GO:0042277,GO:0042470,GO:0042594,GO:0042623,GO:0042886,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043195,GO:0043197,GO:0043198,GO:0043202,GO:0043204,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043230,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043299,GO:0043312,GO:0043412,GO:0043484,GO:0043487,GO:0043488,GO:0043531,GO:0043603,GO:0043624,GO:0043679,GO:0043900,GO:0043902,GO:0043903,GO:0043933,GO:0044087,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044297,GO:0044306,GO:0044309,GO:0044389,GO:0044403,GO:0044419,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044433,GO:0044437,GO:0044444,GO:0044445,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0044788,GO:0044794,GO:0044827,GO:0044829,GO:0045055,GO:0045069,GO:0045070,GO:0045111,GO:0045121,GO:0045184,GO:0045202,GO:0045321,GO:0045807,GO:0045862,GO:0045892,GO:0045934,GO:0045935,GO:0046034,GO:0046483,GO:0046777,GO:0046903,GO:0046907,GO:0048024,GO:0048026,GO:0048259,GO:0048260,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048568,GO:0048583,GO:0048584,GO:0048589,GO:0048598,GO:0048731,GO:0048770,GO:0048856,GO:0050542,GO:0050684,GO:0050685,GO:0050764,GO:0050766,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050792,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051128,GO:0051129,GO:0051130,GO:0051169,GO:0051170,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051219,GO:0051223,GO:0051234,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051261,GO:0051641,GO:0051649,GO:0051702,GO:0051704,GO:0051716,GO:0051726,GO:0051817,GO:0051851,GO:0055085,GO:0055086,GO:0055131,GO:0060090,GO:0060198,GO:0060205,GO:0060255,GO:0060548,GO:0060627,GO:0061013,GO:0061024,GO:0061077,GO:0061083,GO:0061200,GO:0061202,GO:0061462,GO:0061635,GO:0061684,GO:0061738,GO:0061740,GO:0061741,GO:0061919,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070062,GO:0070201,GO:0070382,GO:0070727,GO:0070887,GO:0071211,GO:0071310,GO:0071345,GO:0071496,GO:0071702,GO:0071704,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072318,GO:0072319,GO:0072321,GO:0072341,GO:0072521,GO:0072594,GO:0072665,GO:0072666,GO:0080090,GO:0080134,GO:0080135,GO:0080171,GO:0090087,GO:0090287,GO:0090304,GO:0090559,GO:0097159,GO:0097212,GO:0097213,GO:0097214,GO:0097367,GO:0097447,GO:0097458,GO:0097708,GO:0098552,GO:0098575,GO:0098576,GO:0098588,GO:0098589,GO:0098793,GO:0098794,GO:0098805,GO:0098852,GO:0098857,GO:0098984,GO:0099080,GO:0099081,GO:0099503,GO:0099512,GO:0099513,GO:0099522,GO:0099523,GO:0099524,GO:0099572,GO:0101002,GO:0101031,GO:0120025,GO:0120038,GO:0150034,GO:1900034,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901567,GO:1901575,GO:1902679,GO:1902903,GO:1902904,GO:1902946,GO:1903311,GO:1903313,GO:1903332,GO:1903334,GO:1903506,GO:1903507,GO:1903561,GO:1903900,GO:1903902,GO:1904589,GO:1904592,GO:1904593,GO:1904764,GO:1904813,GO:1905710,GO:1990124,GO:1990833,GO:1990836,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K03283	ko03040,ko04010,ko04141,ko04144,ko04213,ko04612,ko04915,ko05134,ko05145,ko05162,ko05164,ko05169,map03040,map04010,map04141,map04144,map04213,map04612,map04915,map05134,map05145,map05162,map05164,map05169	M00353,M00355	-	-	ko00000,ko00001,ko00002,ko01009,ko03009,ko03029,ko03041,ko03051,ko03110,ko04131,ko04147,ko04516	1.A.33.1	-	-	HSP70
k59_163779_1	944547.ABLL_1038	9.09e-06	52.8	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42NUE@68525|delta/epsilon subdivisions,2YN8X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_163779_2	1128398.Curi_c24140	8.88e-19	83.6	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,26A5I@186813|unclassified Clostridiales	186801|Clostridia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_7156_1	335543.Sfum_0057	2.74e-55	183.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMP4@28221|Deltaproteobacteria,2MQD5@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_1064834_1	326442.PSHAa2386	3.42e-97	308.0	COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,1RPRK@1236|Gammaproteobacteria,2Q0HE@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	dpp4	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
k59_1104095_1	1121930.AQXG01000003_gene2624	2.33e-07	56.2	COG2197@1|root,COG2197@2|Bacteria,4NR4G@976|Bacteroidetes	976|Bacteroidetes	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_1182696_1	467661.RKLH11_3878	1.13e-65	202.0	COG3415@1|root,COG3415@2|Bacteria,1RM0K@1224|Proteobacteria,2UBBP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG3415 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29
k59_1182696_2	467661.RKLH11_3922	1.94e-19	82.4	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_320210_1	713587.THITH_13175	2.06e-54	174.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,1WX50@135613|Chromatiales	135613|Chromatiales	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k59_711826_1	1123399.AQVE01000004_gene2618	8.63e-22	97.8	COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,1S0GX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Type VI secretion	fha1	-	-	ko:K07169,ko:K11894,ko:K11913	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko02044	3.A.23.1	-	-	FHA
k59_711826_2	1408445.JHXP01000002_gene1374	1.03e-27	103.0	COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria,1JEH4@118969|Legionellales	118969|Legionellales	S	Domain of unknown function (DUF1820)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1820
k59_907950_1	314345.SPV1_05467	1.12e-84	266.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria	1224|Proteobacteria	Q	COG1233 Phytoene dehydrogenase and related proteins	-	-	1.3.99.23,5.2.1.13	ko:K09516,ko:K09835	ko00830,ko00906,ko01100,ko01110,map00830,map00906,map01100,map01110	M00097	R07163,R07512	RC01835,RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
k59_85893_1	311402.Avi_2710	2.88e-25	97.1	COG3383@1|root,COG3383@2|Bacteria,1QUPZ@1224|Proteobacteria,2TWJY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4
k59_85893_2	367336.OM2255_04045	1.39e-27	109.0	COG0665@1|root,COG0665@2|Bacteria,1MVG3@1224|Proteobacteria,2TRYR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_1064858_1	335543.Sfum_3291	2.36e-56	193.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MQ86@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_242217_1	998674.ATTE01000001_gene3896	9.73e-100	301.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,45ZYQ@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
k59_202617_1	396588.Tgr7_1608	1.51e-34	135.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,1WWWM@135613|Chromatiales	135613|Chromatiales	O	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_7190_1	980584.AFPB01000086_gene2474	2.94e-40	147.0	COG0560@1|root,COG3830@1|root,COG0560@2|Bacteria,COG3830@2|Bacteria,4NHAG@976|Bacteroidetes,1HWZK@117743|Flavobacteriia,406YP@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	ET	ACT domain	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
k59_202624_1	1260251.SPISAL_04230	2.02e-93	284.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,1WW8H@135613|Chromatiales	135613|Chromatiales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
k59_477144_1	1267005.KB911262_gene3360	1.2e-73	235.0	COG5379@1|root,COG5379@2|Bacteria,1MWG8@1224|Proteobacteria,2TQKH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase	btaA	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
k59_242250_1	396588.Tgr7_2330	2.52e-71	241.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_555490_1	1158762.KB898042_gene971	4.06e-06	48.1	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1WVW6@135613|Chromatiales	135613|Chromatiales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_555490_2	1384056.N787_00425	1.19e-59	196.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1X47D@135614|Xanthomonadales	135614|Xanthomonadales	E	Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine	metX	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_124769_1	933262.AXAM01000025_gene3420	1.11e-80	263.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2MHQW@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1143108_1	1232437.KL662016_gene1052	3.02e-97	304.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MJFX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
k59_868704_2	1035191.HMPREF0185_00801	1.01e-09	58.2	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,2KGKV@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_594735_1	247634.GPB2148_3730	1.1e-18	84.3	COG0258@1|root,COG0258@2|Bacteria,1RAAR@1224|Proteobacteria,1RN1S@1236|Gammaproteobacteria,1J5ZC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG0258 5'-3' exonuclease (including N-terminal domain of PolI)	exo	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
k59_594735_2	545276.KB898727_gene377	3.43e-61	193.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1WWXG@135613|Chromatiales	135613|Chromatiales	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
k59_437823_1	335543.Sfum_3689	6.49e-20	86.7	COG1309@1|root,COG1309@2|Bacteria,1PFBP@1224|Proteobacteria,43A4U@68525|delta/epsilon subdivisions,2X2CD@28221|Deltaproteobacteria,2MSAM@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
k59_437823_2	944480.ATUV01000001_gene601	7.42e-72	228.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42YGX@68525|delta/epsilon subdivisions,2WTHT@28221|Deltaproteobacteria,2M7JG@213113|Desulfurellales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_751413_2	9555.ENSPANP00000012919	1.62e-171	479.0	COG5040@1|root,KOG0841@2759|Eukaryota,38FIW@33154|Opisthokonta,3BHQ4@33208|Metazoa,3CZ9G@33213|Bilateria,48AED@7711|Chordata,48ZM3@7742|Vertebrata,3J2H0@40674|Mammalia,35FPF@314146|Euarchontoglires,4M9X3@9443|Primates,35WUI@314294|Cercopithecoidea	33208|Metazoa	O	Belongs to the 14-3-3 family	YWHAQ	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006605,GO:0006810,GO:0006886,GO:0007154,GO:0007165,GO:0007264,GO:0008022,GO:0008104,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0019219,GO:0019222,GO:0019904,GO:0023052,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032879,GO:0032991,GO:0033036,GO:0034613,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0035556,GO:0042802,GO:0042886,GO:0043269,GO:0043271,GO:0044325,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0045892,GO:0045934,GO:0046907,GO:0047485,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051252,GO:0051253,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0070727,GO:0071702,GO:0071705,GO:0071889,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K16197	ko04013,ko04110,ko04114,ko04151,ko04212,ko04390,ko04391,ko05161,ko05169,ko05203,map04013,map04110,map04114,map04151,map04212,map04390,map04391,map05161,map05169,map05203	-	-	-	ko00000,ko00001,ko03400,ko04147	-	-	-	14-3-3
k59_908050_1	1121405.dsmv_3193	8.63e-48	158.0	28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,42QRB@68525|delta/epsilon subdivisions,2WMSD@28221|Deltaproteobacteria,2MNBV@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3750)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3750
k59_986917_1	883078.HMPREF9695_03320	2.54e-31	126.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,3JS2S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_790649_1	667014.Thein_2204	3.62e-68	218.0	28I4Y@1|root,2Z88D@2|Bacteria,2GI90@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1203744_1	96561.Dole_3007	8.57e-63	199.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42QDN@68525|delta/epsilon subdivisions,2WKRW@28221|Deltaproteobacteria,2MMXT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_425961_1	941639.BCO26_2915	9.9e-15	79.0	COG3385@1|root,COG3385@2|Bacteria,1TPH7@1239|Firmicutes,4HB3I@91061|Bacilli,1ZE78@1386|Bacillus	91061|Bacilli	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_183905_1	1499967.BAYZ01000181_gene4480	3.75e-110	323.0	COG0413@1|root,COG0413@2|Bacteria,2NP1G@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_733040_1	338966.Ppro_2773	2.62e-103	312.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_183933_1	933262.AXAM01000001_gene339	5.25e-86	265.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2MHUV@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_694177_1	272624.lpg1713	4.64e-62	201.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1JCZR@118969|Legionellales	118969|Legionellales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_694177_2	864702.OsccyDRAFT_5020	5.43e-16	75.9	COG0528@1|root,COG0528@2|Bacteria,1G0CR@1117|Cyanobacteria,1H78D@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_108501_1	247639.MGP2080_01626	2.4e-75	248.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	bisC	-	-	ko:K08351	ko00780,ko01100,map00780,map01100	-	R10127	RC03056	ko00000,ko00001,ko01000,ko02000	5.A.3.4	-	-	Molybdopterin,Molydop_binding
k59_382080_1	1472716.KBK24_0118645	3.63e-50	179.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VM2H@28216|Betaproteobacteria,1K0UN@119060|Burkholderiaceae	28216|Betaproteobacteria	L	helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1246506_2	1026955.F5B3R7_9CAUD	2.69e-06	52.8	4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses  no RNA stage	10239|Viruses	S	N-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_498195_1	118161.KB235922_gene387	2.06e-38	145.0	COG5361@1|root,COG5361@2|Bacteria,1GIK1@1117|Cyanobacteria,3VMQJ@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_616440_1	1049564.TevJSym_ac00330	3.25e-47	162.0	2CGG3@1|root,33XQ6@2|Bacteria,1NWYE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_458810_1	614083.AWQR01000001_gene3064	5.29e-61	202.0	COG1752@1|root,COG1752@2|Bacteria,1R7RX@1224|Proteobacteria,2VMTI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_810068_1	1121405.dsmv_2528	2.07e-98	299.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,42MQ1@68525|delta/epsilon subdivisions,2WJII@28221|Deltaproteobacteria,2MHPJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k59_498224_1	1227739.Hsw_0112	2.27e-15	76.3	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,47KPP@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
k59_498224_2	722419.PH505_aa00180	5.83e-40	138.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,2Q25U@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0019842,GO:0031406,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0072341,GO:0097159,GO:1901265,GO:1901363	1.5.1.3	ko:K00287,ko:K18590	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	iECBD_1354.ECBD_3567,iECDH1ME8569_1439.ECDH1ME8569_0047,iECNA114_1301.ECNA114_0036,iEcDH1_1363.EcDH1_3551,iEcSMS35_1347.EcSMS35_0050,iG2583_1286.G2583_0050,iJN746.PP_5132,iNRG857_1313.NRG857_00250,iUMN146_1321.UM146_23020	DHFR_1
k59_1246543_1	1121403.AUCV01000012_gene4110	1.32e-60	211.0	COG0308@1|root,COG3016@1|root,COG0308@2|Bacteria,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WQAR@28221|Deltaproteobacteria,2MPWA@213118|Desulfobacterales	28221|Deltaproteobacteria	EO	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2,Peptidase_M1
k59_1164251_1	1089455.MOPEL_135_01630	2.72e-24	103.0	COG0657@1|root,COG0657@2|Bacteria,2GNKU@201174|Actinobacteria,4F6UH@85018|Dermatophilaceae	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,CBM_2,Peptidase_S9
k59_27475_1	338963.Pcar_1239	1.64e-89	275.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,43TT3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_733166_1	1282876.BAOK01000001_gene2733	3.1e-83	262.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,4BRTT@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	alkK	-	6.2.1.44,6.2.1.48	ko:K00666,ko:K02182,ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1125282_1	1502852.FG94_02070	1.42e-08	58.2	COG0500@1|root,COG0500@2|Bacteria,1QUNM@1224|Proteobacteria,2WGKP@28216|Betaproteobacteria,4791D@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
k59_108606_1	1242864.D187_002300	4.81e-114	344.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_426155_1	1348114.OM33_05720	0.000211	48.9	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,2Q0GY@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG2206 HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
k59_1048224_1	667014.Thein_0882	3.89e-83	275.0	COG1197@1|root,COG1197@2|Bacteria,2GHGT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_890109_1	384765.SIAM614_02581	4.49e-74	239.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_226467_1	751994.AGIG01000009_gene1058	3.77e-45	150.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1JATU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_226467_2	555778.Hneap_0314	7.76e-07	48.9	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1WXDE@135613|Chromatiales	135613|Chromatiales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_1246575_1	1121422.AUMW01000001_gene2358	1.82e-54	177.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,261JF@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
k59_890117_1	903818.KI912269_gene306	1.44e-26	108.0	COG0548@1|root,COG0548@2|Bacteria,3Y2IF@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
k59_890117_2	1461577.CCMH01000037_gene35	1.3e-13	72.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1HYDI@117743|Flavobacteriia	976|Bacteroidetes	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_66554_1	314345.SPV1_09613	1.11e-14	73.6	COG1075@1|root,COG1075@2|Bacteria,1N435@1224|Proteobacteria	1224|Proteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1048243_1	935261.JAGL01000002_gene1397	3.8e-75	247.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2TSZ9@28211|Alphaproteobacteria,43GQ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	MA20_17010	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_1164313_1	1278309.KB907099_gene3023	4.22e-19	90.5	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,1RMAF@1236|Gammaproteobacteria,1XHG3@135619|Oceanospirillales	135619|Oceanospirillales	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
k59_1246593_1	926561.KB900618_gene15	2.65e-17	80.1	COG0384@1|root,COG0384@2|Bacteria,1TPPX@1239|Firmicutes,247ZD@186801|Clostridia,3WC1S@53433|Halanaerobiales	186801|Clostridia	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
k59_1246593_2	1168059.KB899087_gene2966	5.22e-10	63.9	COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2TR1M@28211|Alphaproteobacteria,3EYE9@335928|Xanthobacteraceae	28211|Alphaproteobacteria	T	histidine kinase A domain protein	MA20_19630	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
k59_458904_1	323848.Nmul_A0997	3.41e-67	214.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,372Z7@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	ydiA	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
k59_27538_1	1121004.ATVC01000001_gene411	4.43e-49	174.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,2KSSG@206351|Neisseriales	206351|Neisseriales	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_1246599_1	9606.ENSP00000275603	1.06e-99	303.0	COG0459@1|root,KOG0359@2759|Eukaryota,38EFP@33154|Opisthokonta,3BEDS@33208|Metazoa,3CRMI@33213|Bilateria,48693@7711|Chordata,48W89@7742|Vertebrata,3J5TR@40674|Mammalia,35IY1@314146|Euarchontoglires,4MAFU@9443|Primates,4MWCC@9604|Hominidae	33208|Metazoa	O	assists the folding of proteins upon ATP hydrolysis	CCT6A	GO:0000003,GO:0000226,GO:0001669,GO:0002199,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005832,GO:0005856,GO:0005874,GO:0006457,GO:0006458,GO:0006810,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007098,GO:0007099,GO:0007276,GO:0007283,GO:0007338,GO:0007339,GO:0008037,GO:0008104,GO:0008150,GO:0008565,GO:0009566,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009988,GO:0010556,GO:0010557,GO:0010604,GO:0010638,GO:0012505,GO:0015031,GO:0015630,GO:0015833,GO:0016043,GO:0019219,GO:0019222,GO:0019904,GO:0019953,GO:0022402,GO:0022414,GO:0022607,GO:0030141,GO:0031023,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031410,GO:0031647,GO:0031982,GO:0032204,GO:0032206,GO:0032210,GO:0032212,GO:0032501,GO:0032504,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0034622,GO:0035036,GO:0042886,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044183,GO:0044297,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044703,GO:0045184,GO:0045935,GO:0048232,GO:0048518,GO:0048522,GO:0048609,GO:0050789,GO:0050794,GO:0050821,GO:0051052,GO:0051054,GO:0051082,GO:0051128,GO:0051130,GO:0051131,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051298,GO:0051704,GO:0060255,GO:0060341,GO:0061077,GO:0065003,GO:0065007,GO:0065008,GO:0070201,GO:0070202,GO:0070203,GO:0070925,GO:0071702,GO:0071705,GO:0071840,GO:0071987,GO:0080090,GO:0097223,GO:0097708,GO:0098534,GO:0099080,GO:0099081,GO:0099503,GO:0099512,GO:0099513,GO:0101031,GO:1901998,GO:1903827,GO:1903829,GO:1904356,GO:1904358,GO:1904814,GO:1904816,GO:1904851,GO:1904951,GO:2000112,GO:2000278,GO:2000573,GO:2001252	-	ko:K09498	-	-	-	-	ko00000,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_576476_1	118797.XP_007467759.1	1.19e-131	377.0	COG1308@1|root,KOG2239@2759|Eukaryota,39C57@33154|Opisthokonta,3BB6N@33208|Metazoa,3CRB7@33213|Bilateria,486WS@7711|Chordata,491PY@7742|Vertebrata,3J4GF@40674|Mammalia,4J6CX@91561|Cetartiodactyla	33208|Metazoa	K	nascent polypeptide-associated complex	NACA	GO:0000003,GO:0002376,GO:0002520,GO:0003006,GO:0003674,GO:0003712,GO:0003713,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006996,GO:0007010,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0008134,GO:0008150,GO:0009653,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010556,GO:0010557,GO:0010604,GO:0010927,GO:0016043,GO:0017025,GO:0019219,GO:0019222,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0030029,GO:0030036,GO:0030097,GO:0030154,GO:0030239,GO:0031032,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032501,GO:0032502,GO:0032504,GO:0032989,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044424,GO:0044464,GO:0044703,GO:0045935,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048534,GO:0048609,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051146,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0055001,GO:0055002,GO:0060216,GO:0060255,GO:0061061,GO:0065007,GO:0070925,GO:0071840,GO:0080090,GO:0097435,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2001141	-	ko:K03626	-	-	-	-	ko00000	-	-	-	NAC
k59_382272_1	1415779.JOMH01000001_gene924	4.57e-29	114.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1XCRK@135614|Xanthomonadales	135614|Xanthomonadales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
k59_263865_1	10181.XP_004875050.1	4.5e-122	354.0	COG0197@1|root,KOG0857@2759|Eukaryota,38CBG@33154|Opisthokonta,3B9AY@33208|Metazoa,3CSX1@33213|Bilateria,480F2@7711|Chordata,48ZG9@7742|Vertebrata,3JB05@40674|Mammalia,35JZW@314146|Euarchontoglires,4PZ8X@9989|Rodentia	33208|Metazoa	J	60S ribosomal protein	RPL10	GO:0000003,GO:0000027,GO:0000122,GO:0000184,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005829,GO:0005840,GO:0006139,GO:0006355,GO:0006357,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006417,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007275,GO:0007276,GO:0007283,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009790,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0012505,GO:0015031,GO:0015833,GO:0015934,GO:0016043,GO:0016070,GO:0016071,GO:0019219,GO:0019222,GO:0019439,GO:0019538,GO:0019953,GO:0022414,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033036,GO:0033365,GO:0034248,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042886,GO:0042981,GO:0043043,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044703,GO:0045047,GO:0045182,GO:0045184,GO:0045892,GO:0045934,GO:0046483,GO:0046700,GO:0046907,GO:0048232,GO:0048513,GO:0048519,GO:0048523,GO:0048568,GO:0048609,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051252,GO:0051253,GO:0051641,GO:0051649,GO:0051704,GO:0060255,GO:0060548,GO:0065003,GO:0065007,GO:0070727,GO:0070925,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071826,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0080090,GO:0090150,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990403,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02866	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_426243_1	96561.Dole_0848	1.13e-80	256.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2MIZ1@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Starch synthase catalytic	-	-	2.4.1.21,3.2.1.1	ko:K00703,ko:K01176	ko00500,ko01100,ko01110,ko02026,ko04973,map00500,map01100,map01110,map02026,map04973	M00565	R02108,R02112,R02421,R11262	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GH13,GT5	-	Glyco_trans_1_4,Glyco_transf_5,Glycos_transf_1
k59_890179_1	314285.KT71_02272	4.71e-98	302.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1J4NF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_616569_1	1033802.SSPSH_000255	4.39e-15	73.9	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	outer membrane protein W	ompW	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
k59_616569_2	448385.sce6073	4.17e-88	264.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,42UKT@68525|delta/epsilon subdivisions,2WQR0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_850730_1	43179.ENSSTOP00000012435	4.15e-221	619.0	COG0055@1|root,KOG1350@2759|Eukaryota,38CQ6@33154|Opisthokonta,3BAHK@33208|Metazoa,3CV2G@33213|Bilateria,4851Z@7711|Chordata,497E8@7742|Vertebrata,3J5C0@40674|Mammalia,35JYC@314146|Euarchontoglires,4Q889@9989|Rodentia	33208|Metazoa	C	proton-transporting ATP synthase activity, rotational mechanism	ATP5B	GO:0000003,GO:0000166,GO:0000275,GO:0001525,GO:0001568,GO:0001944,GO:0002119,GO:0002164,GO:0003006,GO:0003008,GO:0003674,GO:0003824,GO:0005102,GO:0005215,GO:0005488,GO:0005509,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0005754,GO:0005759,GO:0005886,GO:0005929,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006839,GO:0006873,GO:0006885,GO:0006897,GO:0006898,GO:0006928,GO:0006929,GO:0006933,GO:0006950,GO:0006952,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0007162,GO:0007275,GO:0007548,GO:0007568,GO:0007588,GO:0007610,GO:0007617,GO:0007618,GO:0007631,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0008340,GO:0008406,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009295,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009790,GO:0009791,GO:0009892,GO:0009986,GO:0009987,GO:0010259,GO:0010468,GO:0010594,GO:0010595,GO:0010605,GO:0010629,GO:0010632,GO:0010634,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016043,GO:0016192,GO:0016310,GO:0016462,GO:0016469,GO:0016477,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017144,GO:0018130,GO:0019098,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0019725,GO:0019829,GO:0019866,GO:0019904,GO:0019953,GO:0022414,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030003,GO:0030004,GO:0030155,GO:0030228,GO:0030334,GO:0030335,GO:0030421,GO:0030554,GO:0030641,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0035239,GO:0035295,GO:0035639,GO:0036094,GO:0036442,GO:0038024,GO:0040011,GO:0040012,GO:0040017,GO:0040024,GO:0040039,GO:0042287,GO:0042288,GO:0042407,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0042645,GO:0042742,GO:0042755,GO:0042776,GO:0042995,GO:0043050,GO:0043167,GO:0043168,GO:0043169,GO:0043207,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043492,GO:0043532,GO:0043535,GO:0043536,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044703,GO:0044769,GO:0045121,GO:0045137,GO:0045259,GO:0045261,GO:0045267,GO:0046034,GO:0046390,GO:0046483,GO:0046872,GO:0046907,GO:0046933,GO:0046961,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048598,GO:0048608,GO:0048609,GO:0048646,GO:0048731,GO:0048856,GO:0048870,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050829,GO:0050896,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051270,GO:0051272,GO:0051453,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051707,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0055086,GO:0060255,GO:0061024,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0071840,GO:0071944,GO:0072358,GO:0072359,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0097159,GO:0097367,GO:0097730,GO:0098542,GO:0098589,GO:0098655,GO:0098657,GO:0098660,GO:0098662,GO:0098771,GO:0098796,GO:0098798,GO:0098800,GO:0098805,GO:0098857,GO:0099131,GO:0099132,GO:0120025,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902600,GO:1990542,GO:2000145,GO:2000147	3.6.3.14	ko:K02133	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_458964_1	1123400.KB904749_gene720	1.14e-30	124.0	COG1100@1|root,COG1100@2|Bacteria,1QXSV@1224|Proteobacteria,1S5FA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	50S ribosome-binding GTPase	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	DUF697,MMR_HSR1
k59_616577_1	266835.14021381	2.6e-76	241.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,2TS9C@28211|Alphaproteobacteria,43NQN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Aminotransferase	tyrB	-	2.6.1.1,2.6.1.57	ko:K00813,ko:K00832	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00024,M00025,M00034,M00040	R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_654219_1	1050202.KB913024_gene2382	7.98e-16	81.3	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,408IC@622450|Actinopolysporales	201174|Actinobacteria	S	Uncharacterised protein, DegV family COG1307	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DegV
k59_694350_1	1304885.AUEY01000013_gene3108	2.82e-18	84.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2MID1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM PhoH family protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
k59_616589_1	1205753.A989_14432	1.02e-44	164.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,1X6AG@135614|Xanthomonadales	135614|Xanthomonadales	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
k59_772415_1	891968.Anamo_0095	1.65e-29	121.0	COG2414@1|root,COG2414@2|Bacteria,3TAA6@508458|Synergistetes	508458|Synergistetes	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_616596_1	1123400.KB904749_gene720	5.8e-31	124.0	COG1100@1|root,COG1100@2|Bacteria,1QXSV@1224|Proteobacteria,1S5FA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	50S ribosome-binding GTPase	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	DUF697,MMR_HSR1
k59_1164418_1	1232437.KL662042_gene2036	2.07e-23	95.5	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,42SFZ@68525|delta/epsilon subdivisions,2WPY5@28221|Deltaproteobacteria,2MNXZ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_928157_2	706587.Desti_3990	1.93e-36	132.0	COG0778@1|root,COG1148@1|root,COG0778@2|Bacteria,COG1148@2|Bacteria,1R4E3@1224|Proteobacteria,42RVJ@68525|delta/epsilon subdivisions,2WNCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Nitroreductase
k59_263937_2	428125.CLOLEP_03005	5.03e-27	110.0	COG3677@1|root,COG3677@2|Bacteria,1V800@1239|Firmicutes,24UYI@186801|Clostridia	186801|Clostridia	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_459022_1	1304275.C41B8_11553	1.01e-119	358.0	COG3425@1|root,COG3425@2|Bacteria,1MU4K@1224|Proteobacteria,1S16F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	synthase	-	-	2.3.3.10	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
k59_1164445_1	933262.AXAM01000081_gene2264	5.55e-84	258.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2WJX5@28221|Deltaproteobacteria,2MHX3@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_850789_2	236097.ADG881_2625	5.13e-37	144.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1XI39@135619|Oceanospirillales	135619|Oceanospirillales	M	(Lipo)protein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
k59_733353_1	61853.ENSNLEP00000008862	4.65e-195	558.0	KOG2326@1|root,KOG2326@2759|Eukaryota,38H1Y@33154|Opisthokonta,3BAAS@33208|Metazoa,3CV59@33213|Bilateria,483WH@7711|Chordata,48YV6@7742|Vertebrata,3JD79@40674|Mammalia,35E0Q@314146|Euarchontoglires,4MBKA@9443|Primates	33208|Metazoa	L	Ku C terminal domain like	XRCC5	GO:0000228,GO:0000723,GO:0000726,GO:0000781,GO:0000782,GO:0000783,GO:0000784,GO:0001067,GO:0001775,GO:0001817,GO:0001819,GO:0001932,GO:0001934,GO:0002218,GO:0002244,GO:0002252,GO:0002253,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002520,GO:0002682,GO:0002684,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003690,GO:0003723,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006310,GO:0006355,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006970,GO:0006972,GO:0006974,GO:0006996,GO:0007275,GO:0007399,GO:0008022,GO:0008026,GO:0008047,GO:0008094,GO:0008104,GO:0008150,GO:0008152,GO:0008283,GO:0009314,GO:0009628,GO:0009651,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010165,GO:0010212,GO:0010332,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010629,GO:0010638,GO:0010639,GO:0010720,GO:0012505,GO:0016020,GO:0016032,GO:0016043,GO:0016192,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019042,GO:0019043,GO:0019219,GO:0019220,GO:0019222,GO:0019899,GO:0022008,GO:0030097,GO:0030141,GO:0030154,GO:0030234,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031347,GO:0031349,GO:0031399,GO:0031401,GO:0031410,GO:0031625,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032200,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032392,GO:0032479,GO:0032481,GO:0032501,GO:0032502,GO:0032508,GO:0032940,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033044,GO:0033365,GO:0033554,GO:0033674,GO:0034097,GO:0034502,GO:0034613,GO:0034641,GO:0034774,GO:0036230,GO:0042119,GO:0042127,GO:0042162,GO:0042221,GO:0042325,GO:0042327,GO:0042538,GO:0042592,GO:0042623,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043549,GO:0043564,GO:0043565,GO:0044087,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044389,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044877,GO:0045055,GO:0045088,GO:0045089,GO:0045321,GO:0045595,GO:0045597,GO:0045859,GO:0045860,GO:0045892,GO:0045934,GO:0045935,GO:0045937,GO:0046483,GO:0046903,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048660,GO:0048699,GO:0048731,GO:0048856,GO:0048863,GO:0048869,GO:0050767,GO:0050769,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051054,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051276,GO:0051338,GO:0051347,GO:0051641,GO:0051704,GO:0051716,GO:0051960,GO:0051962,GO:0051972,GO:0051973,GO:0060205,GO:0060218,GO:0060249,GO:0060255,GO:0060284,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070035,GO:0070198,GO:0070419,GO:0070727,GO:0070887,GO:0071103,GO:0071214,GO:0071310,GO:0071345,GO:0071470,GO:0071472,GO:0071474,GO:0071475,GO:0071478,GO:0071479,GO:0071480,GO:0071481,GO:0071704,GO:0071840,GO:0071944,GO:0075713,GO:0080090,GO:0080134,GO:0090304,GO:0097159,GO:0097708,GO:0098687,GO:0098772,GO:0099503,GO:0104004,GO:0140097,GO:1901360,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1904356,GO:1904358,GO:1904429,GO:1904430,GO:1990391,GO:1990823,GO:1990830,GO:1990904,GO:2000026,GO:2000112,GO:2000113,GO:2000278,GO:2000573,GO:2001141,GO:2001251,GO:2001252	-	ko:K10885	ko03450,map03450	M00297	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	Ku,Ku_C,Ku_N,Ku_PK_bind
k59_812983_1	376733.IT41_19790	1.82e-85	266.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria,2PW8K@265|Paracoccus	28211|Alphaproteobacteria	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_931151_1	1121403.AUCV01000006_gene391	1.35e-50	168.0	COG0517@1|root,COG0517@2|Bacteria,1N39X@1224|Proteobacteria,42TS0@68525|delta/epsilon subdivisions,2WQC3@28221|Deltaproteobacteria,2MKHE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_736051_1	487521.OCU_50240	1.24e-54	185.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,233QF@1762|Mycobacteriaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_30568_1	28229.ND2E_3836	6.75e-53	189.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,2Q5XQ@267889|Colwelliaceae	1236|Gammaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_2160,iPC815.YPO2428	B3_4,B5,FDX-ACB,tRNA_bind
k59_461797_1	566466.NOR53_3005	1.94e-120	362.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,1RQJY@1236|Gammaproteobacteria,1J58C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG2939 Carboxypeptidase C (cathepsin A)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
k59_1128138_1	1123228.AUIH01000006_gene2315	2.99e-62	209.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1XHVD@135619|Oceanospirillales	135619|Oceanospirillales	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc,MASE2
k59_1206944_1	1238425.J07HQW2_02748	1.24e-10	67.4	COG0546@1|root,arCOG04692@2157|Archaea,2XUI7@28890|Euryarchaeota,23SAI@183963|Halobacteria	183963|Halobacteria	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
k59_579710_1	745310.G432_10375	1.9e-28	120.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,2U1KH@28211|Alphaproteobacteria,2K128@204457|Sphingomonadales	204457|Sphingomonadales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1050880_1	1122599.AUGR01000001_gene108	2.46e-33	126.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1XJ73@135619|Oceanospirillales	135619|Oceanospirillales	M	Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)	lpxL	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
k59_1088082_1	706587.Desti_0693	7.22e-38	142.0	COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria,2MR0N@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_305719_1	1391188.A0A068EU17_9CAUD	6.08e-37	139.0	4QCD9@10239|Viruses,4QXNP@35237|dsDNA viruses  no RNA stage	10239|Viruses	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_186813_2	565045.NOR51B_1560	1.78e-46	153.0	2DN6U@1|root,32VVA@2|Bacteria,1N6AG@1224|Proteobacteria,1SQ0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cysteine rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_FGFR
k59_893066_1	561177.ANHYDRO_01770	1.2e-09	61.2	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,1V9ZW@1239|Firmicutes,25AZU@186801|Clostridia,22G4U@1570339|Peptoniphilaceae	186801|Clostridia	M	NlpC p60 family protein	spr	-	3.4.17.13	ko:K13694,ko:K19224,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60,SH3_3
k59_1000262_1	1304880.JAGB01000004_gene1485	6.48e-33	124.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
k59_722808_1	243231.GSU0159	1.15e-35	130.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,43SVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	EM	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_800123_1	765911.Thivi_0551	2.86e-107	323.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,1RYPW@1236|Gammaproteobacteria,1WXQI@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k59_879207_1	981327.F925_00290	2.59e-24	94.7	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,3NN4P@468|Moraxellaceae	1236|Gammaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_174138_1	1038860.AXAP01000125_gene1931	3.9e-28	113.0	COG0535@1|root,COG0535@2|Bacteria,1NJZV@1224|Proteobacteria,2U4H8@28211|Alphaproteobacteria,3JXW2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
k59_605452_2	1121456.ATVA01000017_gene87	6.23e-05	44.7	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,2M9J5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
k59_96560_1	1499967.BAYZ01000009_gene5393	7.79e-106	318.0	COG2718@1|root,COG2718@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF444)	yhbH	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444,Haem_oxygenas_2
k59_292013_1	366602.Caul_5358	2.47e-34	132.0	COG3547@1|root,COG3547@2|Bacteria,1Q4TE@1224|Proteobacteria,2TT7C@28211|Alphaproteobacteria,2KIIT@204458|Caulobacterales	204458|Caulobacterales	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_20
k59_330609_1	1121912.AUHD01000006_gene1445	9.3e-45	146.0	COG3460@1|root,COG3460@2|Bacteria,4NQFV@976|Bacteroidetes,1I2UD@117743|Flavobacteriia	976|Bacteroidetes	Q	With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
k59_330609_2	316058.RPB_3641	7.35e-15	73.6	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2TTC4@28211|Alphaproteobacteria,3JTGS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_55904_1	743836.AYNA01000029_gene2433	9.95e-43	160.0	COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,2TVX5@28211|Alphaproteobacteria,36ZSB@31993|Methylocystaceae	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
k59_96586_1	426117.M446_2875	2.24e-35	137.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,1JZHP@119045|Methylobacteriaceae	28211|Alphaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C_2,Acyltransferase,PP-binding
k59_565845_1	670307.HYPDE_38998	1.38e-44	157.0	COG4246@1|root,COG4246@2|Bacteria,1N7Y1@1224|Proteobacteria,2TTZW@28211|Alphaproteobacteria,3N746@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
k59_487579_1	595460.RRSWK_02069	5.2e-51	175.0	COG0842@1|root,COG0842@2|Bacteria,2IXGJ@203682|Planctomycetes	203682|Planctomycetes	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_683444_3	1121396.KB892901_gene2171	1.66e-07	56.2	COG1409@1|root,COG3291@1|root,COG4733@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,1QZGY@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5017,DUF839,Exo_endo_phos,PKD
k59_800177_1	396588.Tgr7_0191	3.07e-181	531.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales	135613|Chromatiales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_292033_1	1122236.KB905141_gene1748	5.97e-60	193.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,2KMM3@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
k59_370378_1	414996.IL38_01910	4.42e-07	59.7	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,408NH@622450|Actinopolysporales	201174|Actinobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9
k59_683464_1	1205680.CAKO01000038_gene1777	3.57e-61	201.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TQRA@28211|Alphaproteobacteria,2JPQZ@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_213413_1	977880.RALTA_A0128	5.86e-52	175.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2VIH8@28216|Betaproteobacteria,1K37A@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	d-isomer specific 2-hydroxyacid dehydrogenase, nad-binding	ghrA	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
k59_96611_1	864073.HFRIS_004003	5.56e-44	157.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,476PV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
k59_722902_1	472759.Nhal_1420	2.34e-45	162.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,1RQ4U@1236|Gammaproteobacteria,1X10W@135613|Chromatiales	135613|Chromatiales	U	Pilus formation protein N terminal region	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Secretin,T2SS-T3SS_pil_N
k59_761490_1	335543.Sfum_0202	6.58e-114	336.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2MQ5T@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378,ko:K13380	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
k59_761490_2	1121877.JQKF01000009_gene581	1.6e-06	48.5	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4CN4G@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_1192954_1	1322246.BN4_11747	5.84e-49	166.0	COG2875@1|root,COG2875@2|Bacteria,1MVYY@1224|Proteobacteria,42P88@68525|delta/epsilon subdivisions,2WMR1@28221|Deltaproteobacteria,2M959@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cbiF	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
k59_643932_1	1121405.dsmv_3645	3.37e-59	203.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MI5C@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_643932_2	1265505.ATUG01000001_gene3714	7.98e-89	290.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MIYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_1000428_1	1033802.SSPSH_003037	1.63e-93	300.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046487,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_436,iECOK1_1307.ECOK1_1491,iECS88_1305.ECS88_1416,iJN746.PP_2112,iUMN146_1321.UM146_10390,iUTI89_1310.UTI89_C1547	Aconitase,Aconitase_C
k59_1153463_1	247634.GPB2148_990	4.95e-68	234.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_565907_1	713586.KB900536_gene589	3.79e-65	208.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S0GF@1236|Gammaproteobacteria,1X0AW@135613|Chromatiales	135613|Chromatiales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
k59_370455_1	1121033.AUCF01000045_gene3991	8.33e-118	345.0	COG4307@1|root,COG4307@2|Bacteria,1MW31@1224|Proteobacteria,2TRR9@28211|Alphaproteobacteria,2JQCY@204441|Rhodospirillales	204441|Rhodospirillales	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
k59_213461_1	1121472.AQWN01000006_gene1762	4.13e-59	194.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,260KR@186807|Peptococcaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_1074707_1	553219.CAMSH0001_0136	2.59e-07	57.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2YMNI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Pseudouridine synthase	sfhB	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
k59_370459_2	1210884.HG799466_gene12431	6.06e-17	84.3	COG0119@1|root,COG0119@2|Bacteria,2IX7Z@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_1039623_1	933262.AXAM01000021_gene475	9.61e-36	125.0	2DE6G@1|root,32U2S@2|Bacteria,1N4FF@1224|Proteobacteria,42TMY@68525|delta/epsilon subdivisions,2WQEV@28221|Deltaproteobacteria,2MKMW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ATP synthase I chain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
k59_58486_1	393595.ABO_0835	6.72e-79	238.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,1XHB3@135619|Oceanospirillales	135619|Oceanospirillales	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	-	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k59_58486_2	1305735.JAFT01000005_gene1489	1.05e-10	61.2	COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,2U0WY@28211|Alphaproteobacteria,2PDN9@252301|Oceanicola	28211|Alphaproteobacteria	C	Oxidoreductase FAD-binding domain	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_530179_1	402881.Plav_2665	1.25e-79	250.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2TQQ1@28211|Alphaproteobacteria,1JN1E@119043|Rhodobiaceae	28211|Alphaproteobacteria	J	DALR_2	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
k59_881944_1	743299.Acife_3143	1.86e-24	107.0	28IUD@1|root,2Z8T4@2|Bacteria,1QZHS@1224|Proteobacteria,1RNTX@1236|Gammaproteobacteria,2NC21@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Carboxysome shell peptide mid-region	-	-	-	-	-	-	-	-	-	-	-	-	CsoS2_M
k59_255480_1	1232437.KL662040_gene2136	1.49e-101	308.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_216981_1	1286106.MPL1_03538	3.85e-48	160.0	COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,1RRM7@1236|Gammaproteobacteria,4612C@72273|Thiotrichales	72273|Thiotrichales	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
k59_490255_1	1116472.MGMO_171c00100	2.55e-91	282.0	COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,1RMVT@1236|Gammaproteobacteria,1XDQW@135618|Methylococcales	135618|Methylococcales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	-	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_216985_1	1415779.JOMH01000001_gene2885	5.79e-70	231.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1X57M@135614|Xanthomonadales	135614|Xanthomonadales	E	Sodium alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_1195654_1	1500304.JQKY01000015_gene1885	6.91e-75	236.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,4BBSC@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_373068_1	869213.JCM21142_31209	9.77e-20	90.9	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_490283_1	501479.ACNW01000090_gene2337	1.9e-24	102.0	2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,2U8X3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1238232_1	224914.BMEII0462	4e-79	258.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,1J1TR@118882|Brucellaceae	28211|Alphaproteobacteria	L	DEAD/H associated	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
k59_1238235_1	323261.Noc_1323	8.13e-32	122.0	2DBYQ@1|root,32TYF@2|Bacteria,1N2HM@1224|Proteobacteria,1SB6Y@1236|Gammaproteobacteria,1X1T1@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_450867_1	1232410.KI421426_gene1459	6.34e-71	228.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42PGM@68525|delta/epsilon subdivisions,2X5J8@28221|Deltaproteobacteria,43SW4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1003905_1	1122138.AQUZ01000008_gene3659	2.56e-37	138.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DPHD@85009|Propionibacteriales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_294900_2	1123298.KB904121_gene1917	1.34e-21	95.9	COG0582@1|root,COG0582@2|Bacteria,1UMEE@1239|Firmicutes,4ITVG@91061|Bacilli	91061|Bacilli	L	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
k59_255528_1	572477.Alvin_0279	5.57e-30	124.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,1WWRZ@135613|Chromatiales	135613|Chromatiales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
k59_490304_1	1254432.SCE1572_38725	1.35e-71	230.0	COG5659@1|root,COG5659@2|Bacteria,1MWAV@1224|Proteobacteria,43BD6@68525|delta/epsilon subdivisions,2X6S2@28221|Deltaproteobacteria,2Z0N7@29|Myxococcales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_255532_2	519989.ECTPHS_00230	7.22e-17	78.2	COG0209@1|root,COG0209@2|Bacteria,1P4EH@1224|Proteobacteria,1RP1A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	COG0209 Ribonucleotide reductase, alpha subunit	nrdJb	-	-	-	-	-	-	-	-	-	-	-	-
k59_530264_1	1280954.HPO_18048	8.22e-52	182.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_177234_1	43179.ENSSTOP00000001101	4.49e-108	317.0	COG0105@1|root,KOG0888@2759|Eukaryota,3A1MB@33154|Opisthokonta,3BPIJ@33208|Metazoa,3D20N@33213|Bilateria,4829Y@7711|Chordata,48XS1@7742|Vertebrata,3J7R9@40674|Mammalia,35D44@314146|Euarchontoglires,4Q099@9989|Rodentia	33208|Metazoa	F	protein histidine kinase activity	NME2	GO:0001101,GO:0001678,GO:0001726,GO:0001775,GO:0001932,GO:0001934,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002683,GO:0002761,GO:0002762,GO:0003674,GO:0003700,GO:0003824,GO:0004550,GO:0004672,GO:0004674,GO:0005488,GO:0005504,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006183,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006241,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006979,GO:0007154,GO:0007155,GO:0007165,GO:0007166,GO:0007186,GO:0007187,GO:0007188,GO:0007189,GO:0007229,GO:0007275,GO:0007399,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008289,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009132,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009147,GO:0009148,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010720,GO:0010941,GO:0010975,GO:0010976,GO:0012505,GO:0015949,GO:0016020,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0018130,GO:0019205,GO:0019215,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019725,GO:0019899,GO:0019932,GO:0019933,GO:0019935,GO:0022008,GO:0022607,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0030027,GO:0030100,GO:0030141,GO:0030154,GO:0030334,GO:0030856,GO:0030858,GO:0031090,GO:0031252,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031406,GO:0031410,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031982,GO:0031983,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032940,GO:0033293,GO:0033500,GO:0033554,GO:0033993,GO:0034284,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034774,GO:0035556,GO:0036094,GO:0036211,GO:0036230,GO:0040012,GO:0040026,GO:0040028,GO:0042119,GO:0042127,GO:0042221,GO:0042278,GO:0042325,GO:0042327,GO:0042451,GO:0042455,GO:0042592,GO:0042593,GO:0042802,GO:0042981,GO:0042995,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043408,GO:0043410,GO:0043412,GO:0043434,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044429,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045055,GO:0045321,GO:0045595,GO:0045596,GO:0045597,GO:0045604,GO:0045606,GO:0045616,GO:0045618,GO:0045637,GO:0045638,GO:0045664,GO:0045666,GO:0045682,GO:0045684,GO:0045893,GO:0045935,GO:0045937,GO:0045944,GO:0046036,GO:0046039,GO:0046051,GO:0046128,GO:0046129,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046777,GO:0046903,GO:0046939,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048580,GO:0048582,GO:0048583,GO:0048584,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050678,GO:0050679,GO:0050764,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051259,GO:0051270,GO:0051716,GO:0051960,GO:0051962,GO:0055082,GO:0055086,GO:0060099,GO:0060205,GO:0060255,GO:0060284,GO:0060416,GO:0060548,GO:0060627,GO:0061062,GO:0061063,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070542,GO:0070887,GO:0071229,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071396,GO:0071398,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072522,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0097708,GO:0099503,GO:0101002,GO:0120025,GO:0120035,GO:0140096,GO:0140110,GO:1901068,GO:1901070,GO:1901074,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1901701,GO:1902105,GO:1902106,GO:1902531,GO:1902533,GO:1902680,GO:1903506,GO:1903508,GO:1903706,GO:1903707,GO:1904813,GO:1905153,GO:2000026,GO:2000112,GO:2000145,GO:2000425,GO:2001141	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k59_764166_1	335543.Sfum_0115	1.7e-77	242.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MQT4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase alpha subunit	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_764166_2	335543.Sfum_0544	1.88e-11	60.5	COG1144@1|root,COG1144@2|Bacteria,1NE6F@1224|Proteobacteria,42W4G@68525|delta/epsilon subdivisions,2WS1A@28221|Deltaproteobacteria,2MS3V@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
k59_686307_1	1411123.JQNH01000001_gene419	1.24e-07	52.4	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2TR6C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k59_686307_2	744980.TRICHSKD4_0244	5.19e-46	152.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2U9BY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
k59_1077220_1	9597.XP_008967537.1	6.16e-211	598.0	COG0166@1|root,KOG2446@2759|Eukaryota,38EWT@33154|Opisthokonta,3B93W@33208|Metazoa,3CUZG@33213|Bilateria,489XR@7711|Chordata,48XPM@7742|Vertebrata,3J7QY@40674|Mammalia,358VD@314146|Euarchontoglires,4M8ZW@9443|Primates,4N9CU@9604|Hominidae	33208|Metazoa	F	Phosphoglucose isomerase	GPI	GO:0001701,GO:0001704,GO:0001707,GO:0001775,GO:0002252,GO:0002262,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002637,GO:0002639,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002791,GO:0002793,GO:0003008,GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0005929,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006959,GO:0007275,GO:0007369,GO:0007498,GO:0007599,GO:0007610,GO:0007611,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009410,GO:0009435,GO:0009438,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009888,GO:0009892,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0010466,GO:0010594,GO:0010595,GO:0010605,GO:0010632,GO:0010634,GO:0010941,GO:0010951,GO:0012505,GO:0014070,GO:0014072,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016192,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0016866,GO:0017144,GO:0018130,GO:0019222,GO:0019242,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0019899,GO:0030141,GO:0030162,GO:0030246,GO:0030334,GO:0030335,GO:0031090,GO:0031253,GO:0031323,GO:0031324,GO:0031410,GO:0031625,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032355,GO:0032501,GO:0032502,GO:0032570,GO:0032787,GO:0032879,GO:0032880,GO:0032940,GO:0033500,GO:0033574,GO:0033993,GO:0034101,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034774,GO:0035902,GO:0035994,GO:0036094,GO:0036230,GO:0040012,GO:0040017,GO:0042119,GO:0042180,GO:0042181,GO:0042221,GO:0042493,GO:0042592,GO:0042593,GO:0042866,GO:0042981,GO:0042995,GO:0043005,GO:0043009,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043154,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043278,GO:0043279,GO:0043281,GO:0043299,GO:0043312,GO:0043436,GO:0043523,GO:0043524,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044433,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0045861,GO:0046031,GO:0046034,GO:0046184,GO:0046185,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046686,GO:0046700,GO:0046903,GO:0046939,GO:0048029,GO:0048332,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048598,GO:0048646,GO:0048729,GO:0048856,GO:0048872,GO:0048878,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050877,GO:0050878,GO:0050890,GO:0050896,GO:0051023,GO:0051024,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051156,GO:0051171,GO:0051172,GO:0051179,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051270,GO:0051272,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060170,GO:0060205,GO:0060255,GO:0060359,GO:0060548,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0071704,GO:0071944,GO:0072330,GO:0072347,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097458,GO:0097708,GO:0098588,GO:0098590,GO:0099503,GO:0101002,GO:0120025,GO:0120038,GO:1901135,GO:1901137,GO:1901214,GO:1901215,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901654,GO:1901698,GO:1901700,GO:1903530,GO:1903532,GO:1904813,GO:1904951,GO:2000116,GO:2000117,GO:2000145,GO:2000147	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_1003944_1	1121405.dsmv_2245	2.84e-51	182.0	COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,42N23@68525|delta/epsilon subdivisions,2WKW2@28221|Deltaproteobacteria,2MHZB@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_255554_1	1219077.VAZ01S_016_00040	4.66e-46	159.0	COG3193@1|root,COG3193@2|Bacteria,1R215@1224|Proteobacteria,1S4R1@1236|Gammaproteobacteria,1XZQD@135623|Vibrionales	135623|Vibrionales	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
k59_217075_2	1303692.SFUL_565	1.61e-30	112.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria	201174|Actinobacteria	P	reversible hydration of carbon dioxide	mtcA1	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008270,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
k59_530292_1	420324.KI911939_gene5378	2.65e-93	294.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,1JT8T@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase molybdopterin binding	MA20_17495	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_764193_1	335543.Sfum_1371	2.63e-138	401.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MQ86@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_19724_1	1173027.Mic7113_3739	6.2e-97	300.0	COG0296@1|root,COG0296@2|Bacteria,1GD05@1117|Cyanobacteria,1HEAH@1150|Oscillatoriales	1117|Cyanobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_333406_2	670307.HYPDE_28318	9.28e-21	84.3	COG1773@1|root,COG1773@2|Bacteria,1N6TQ@1224|Proteobacteria	1224|Proteobacteria	C	Belongs to the rubredoxin family	hupI	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k59_333406_3	187272.Mlg_2023	4.21e-22	93.2	COG1773@1|root,COG1773@2|Bacteria,1MV2U@1224|Proteobacteria,1S2ZY@1236|Gammaproteobacteria,1WY2I@135613|Chromatiales	135613|Chromatiales	C	PFAM HupH hydrogenase expression protein, C-terminal conserved region	-	-	-	ko:K03618	-	-	-	-	ko00000	-	-	-	HupH_C
k59_842791_1	395493.BegalDRAFT_3010	2.36e-104	308.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,462JT@72273|Thiotrichales	72273|Thiotrichales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_1238338_1	335543.Sfum_2166	3.98e-87	264.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,2MQBN@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
k59_255599_1	349124.Hhal_2379	2.07e-09	65.1	2DT83@1|root,33J44@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1077266_1	471874.PROSTU_04063	2.34e-21	100.0	28IAE@1|root,2Z8D0@2|Bacteria,1NC6U@1224|Proteobacteria,1RSEY@1236|Gammaproteobacteria,3Z74B@586|Providencia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1077266_3	1117647.M5M_10800	7.78e-24	97.1	COG3637@1|root,COG3637@2|Bacteria,1PXDF@1224|Proteobacteria,1TC33@1236|Gammaproteobacteria,1JBGY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_882088_1	9606.ENSP00000483491	6.21e-138	401.0	COG0706@1|root,KOG1239@2759|Eukaryota,38GVP@33154|Opisthokonta,3BEN4@33208|Metazoa,3CVEW@33213|Bilateria,486KB@7711|Chordata,491U3@7742|Vertebrata,3J6H0@40674|Mammalia,35F3H@314146|Euarchontoglires,4M6A2@9443|Primates,4MZGT@9604|Hominidae	33208|Metazoa	OU	60Kd inner membrane protein	OXA1L	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005759,GO:0006091,GO:0006412,GO:0006414,GO:0006415,GO:0006518,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0008535,GO:0009058,GO:0009059,GO:0009060,GO:0009892,GO:0009987,GO:0010257,GO:0010467,GO:0015980,GO:0016020,GO:0016021,GO:0016043,GO:0017004,GO:0019222,GO:0019538,GO:0019866,GO:0022411,GO:0022607,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032543,GO:0032592,GO:0032780,GO:0032981,GO:0032984,GO:0032991,GO:0033108,GO:0033615,GO:0034622,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043461,GO:0043462,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044877,GO:0045333,GO:0046983,GO:0048519,GO:0050789,GO:0050790,GO:0051259,GO:0051262,GO:0051336,GO:0051341,GO:0051346,GO:0051354,GO:0055114,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070071,GO:0070125,GO:0070126,GO:0070469,GO:0071704,GO:0071840,GO:0097177,GO:0098573,GO:0140053,GO:1901564,GO:1901566,GO:1901576	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
k59_905495_2	404589.Anae109_3527	9.88e-30	115.0	COG1360@1|root,COG1360@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
k59_239453_1	1121396.KB893078_gene786	4.74e-199	569.0	COG4467@1|root,COG4467@2|Bacteria,1PPMF@1224|Proteobacteria	1224|Proteobacteria	S	Involved in initiation control of chromosome replication	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66
k59_200295_1	1121438.JNJA01000001_gene2600	5.71e-49	172.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MR8@68525|delta/epsilon subdivisions,2WIUA@28221|Deltaproteobacteria,2MA08@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_200297_1	9606.ENSP00000234347	8.08e-189	523.0	COG5640@1|root,KOG3627@2759|Eukaryota,39UMG@33154|Opisthokonta,3BKNJ@33208|Metazoa,3D4C0@33213|Bilateria,483K9@7711|Chordata,49357@7742|Vertebrata,3J1IG@40674|Mammalia,35H21@314146|Euarchontoglires,4M7VP@9443|Primates,4MTW0@9604|Hominidae	33208|Metazoa	O	Trypsin-like serine protease	PRTN3	GO:0000122,GO:0000323,GO:0001775,GO:0001817,GO:0001818,GO:0001819,GO:0001906,GO:0001909,GO:0001932,GO:0001934,GO:0002020,GO:0002252,GO:0002253,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002437,GO:0002438,GO:0002440,GO:0002443,GO:0002444,GO:0002446,GO:0002520,GO:0002521,GO:0002526,GO:0002573,GO:0002576,GO:0002682,GO:0002684,GO:0002775,GO:0002777,GO:0002778,GO:0002780,GO:0002812,GO:0003674,GO:0003712,GO:0003714,GO:0003824,GO:0004175,GO:0004252,GO:0005102,GO:0005488,GO:0005515,GO:0005539,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006355,GO:0006357,GO:0006508,GO:0006509,GO:0006518,GO:0006807,GO:0006810,GO:0006873,GO:0006874,GO:0006875,GO:0006887,GO:0006897,GO:0006909,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006956,GO:0006957,GO:0006959,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007596,GO:0007599,GO:0008150,GO:0008152,GO:0008201,GO:0008233,GO:0008236,GO:0008284,GO:0009056,GO:0009057,GO:0009058,GO:0009314,GO:0009411,GO:0009416,GO:0009605,GO:0009607,GO:0009611,GO:0009617,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0012505,GO:0016020,GO:0016043,GO:0016192,GO:0016477,GO:0016787,GO:0017053,GO:0017171,GO:0019219,GO:0019220,GO:0019221,GO:0019222,GO:0019538,GO:0019725,GO:0019730,GO:0019731,GO:0019899,GO:0019955,GO:0022411,GO:0022617,GO:0023051,GO:0023052,GO:0023056,GO:0030003,GO:0030097,GO:0030099,GO:0030100,GO:0030141,GO:0030154,GO:0030163,GO:0030198,GO:0031091,GO:0031093,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031347,GO:0031348,GO:0031399,GO:0031401,GO:0031410,GO:0031640,GO:0031974,GO:0031982,GO:0031983,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032642,GO:0032677,GO:0032682,GO:0032717,GO:0032757,GO:0032879,GO:0032940,GO:0032991,GO:0033619,GO:0033674,GO:0034097,GO:0034330,GO:0034331,GO:0034641,GO:0034774,GO:0035578,GO:0035580,GO:0035821,GO:0036230,GO:0040011,GO:0040012,GO:0040013,GO:0042035,GO:0042036,GO:0042060,GO:0042108,GO:0042119,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042581,GO:0042582,GO:0042592,GO:0042742,GO:0043043,GO:0043062,GO:0043085,GO:0043087,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043547,GO:0043549,GO:0043603,GO:0043604,GO:0043954,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044364,GO:0044403,GO:0044419,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044853,GO:0045055,GO:0045073,GO:0045079,GO:0045087,GO:0045121,GO:0045123,GO:0045216,GO:0045217,GO:0045321,GO:0045414,GO:0045415,GO:0045416,GO:0045806,GO:0045859,GO:0045860,GO:0045892,GO:0045934,GO:0045937,GO:0046903,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048585,GO:0048660,GO:0048661,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0050727,GO:0050728,GO:0050764,GO:0050765,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050817,GO:0050829,GO:0050878,GO:0050896,GO:0050900,GO:0050920,GO:0050922,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051338,GO:0051345,GO:0051347,GO:0051674,GO:0051702,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0060205,GO:0060255,GO:0060627,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070011,GO:0070013,GO:0070887,GO:0070942,GO:0070943,GO:0070944,GO:0070945,GO:0071310,GO:0071345,GO:0071704,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072376,GO:0072503,GO:0072507,GO:0072672,GO:0080090,GO:0080134,GO:0097028,GO:0097029,GO:0097367,GO:0097529,GO:0097530,GO:0097708,GO:0098542,GO:0098589,GO:0098590,GO:0098657,GO:0098771,GO:0098805,GO:0098857,GO:0099503,GO:0101002,GO:0140096,GO:0140110,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901681,GO:1902531,GO:1902533,GO:1902679,GO:1903506,GO:1903507,GO:1904813,GO:1990266,GO:2000112,GO:2000113,GO:2001141	3.4.21.37,3.4.21.46,3.4.21.76	ko:K01327,ko:K01334,ko:K01350	ko04610,ko05150,ko05202,ko05322,map04610,map05150,map05202,map05322	-	-	-	ko00000,ko00001,ko00536,ko01000,ko01002,ko03110,ko04147	-	-	-	Trypsin
k59_1023502_1	420662.Mpe_A3578	6.71e-62	207.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2VIT5@28216|Betaproteobacteria,1KKBA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_1219037_1	485915.Dret_0417	1.98e-58	188.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,42SBS@68525|delta/epsilon subdivisions,2WPKY@28221|Deltaproteobacteria,2MGKF@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_9
k59_592252_1	485916.Dtox_1279	9.47e-14	71.2	COG1035@1|root,COG1143@1|root,COG1035@2|Bacteria,COG1143@2|Bacteria,1TPBM@1239|Firmicutes,24CJH@186801|Clostridia,260PH@186807|Peptococcaceae	186801|Clostridia	C	PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,FrhB_FdhB_C
k59_592252_2	177437.HRM2_22090	2.73e-17	77.8	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria,42RJZ@68525|delta/epsilon subdivisions,2WNDU@28221|Deltaproteobacteria,2MJUB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k59_866383_1	1304885.AUEY01000033_gene1894	1.83e-06	56.2	COG0664@1|root,COG0664@2|Bacteria,1RCF4@1224|Proteobacteria,43BRQ@68525|delta/epsilon subdivisions,2X72K@28221|Deltaproteobacteria,2MJHW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,cNMP_binding
k59_670561_1	1382306.JNIM01000001_gene2836	7.98e-74	247.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_592256_1	224914.BMEII0673	9.37e-68	214.0	COG2220@1|root,COG2220@2|Bacteria,1MUY6@1224|Proteobacteria,2TV26@28211|Alphaproteobacteria,1J29Q@118882|Brucellaceae	28211|Alphaproteobacteria	S	hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
k59_43558_1	391616.OA238_c38840	1.8e-95	288.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2TTH8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_43558_2	926550.CLDAP_08580	2.36e-26	103.0	COG3415@1|root,COG3415@2|Bacteria,2G91K@200795|Chloroflexi	200795|Chloroflexi	L	SPTR B0JRC2 Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
k59_122230_2	1267005.KB911258_gene588	3.02e-26	103.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2TUVR@28211|Alphaproteobacteria,3N7BD@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_788148_1	1121448.DGI_1701	3.62e-06	55.5	COG0823@1|root,COG0823@2|Bacteria,1MX4U@1224|Proteobacteria,42PEP@68525|delta/epsilon subdivisions,2WJUC@28221|Deltaproteobacteria,2M91V@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	tmcD	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_1180283_1	880072.Desac_1171	9.33e-109	322.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2MQB1@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_357327_1	765911.Thivi_1735	3.4e-106	321.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1WWCI@135613|Chromatiales	135613|Chromatiales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_83205_1	188626.HMPREF0321_0247	0.000881	41.6	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,1ZVBA@145357|Dermacoccaceae	201174|Actinobacteria	D	CobQ CobB MinD ParA nucleotide binding domain	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_83205_2	439235.Dalk_2600	2.61e-32	127.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,2MHRK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1238	Peptidase_M48,TPR_14,TPR_16,TPR_19
k59_1219101_1	574087.Acear_0680	4.94e-19	89.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,3WAT7@53433|Halanaerobiales	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
k59_4697_2	1385515.N791_10500	4.65e-43	141.0	COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,1S8V5@1236|Gammaproteobacteria,1X7FM@135614|Xanthomonadales	135614|Xanthomonadales	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
k59_1182065_2	196367.JNFG01000073_gene6229	2.63e-160	463.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VMDU@28216|Betaproteobacteria,1KH1R@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_789936_1	1121271.AUCM01000004_gene1111	1.39e-71	227.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
k59_711262_1	1122603.ATVI01000005_gene3679	4.86e-91	281.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1X35C@135614|Xanthomonadales	135614|Xanthomonadales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
k59_554822_1	998674.ATTE01000001_gene4252	2.14e-76	243.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,46021@72273|Thiotrichales	72273|Thiotrichales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_163122_1	323097.Nham_1170	1.49e-136	395.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,2TUF8@28211|Alphaproteobacteria,3JS8B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k59_280492_1	1410620.SHLA_64c000160	1.18e-61	203.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2TSB9@28211|Alphaproteobacteria,4B7RA@82115|Rhizobiaceae	28211|Alphaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_1025272_1	1149133.ppKF707_1209	1.58e-37	137.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1YEWC@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)	lpxL	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iEC042_1314.EC042_2597,iSF_1195.SF1061,iS_1188.S1138,iYL1228.KPN_01068	Lip_A_acyltrans
k59_868061_1	1121939.L861_20020	4.95e-06	47.4	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XIDG@135619|Oceanospirillales	135619|Oceanospirillales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
k59_868061_2	246200.SPO1255	6.04e-14	72.0	COG2128@1|root,COG2128@2|Bacteria,1PQ1G@1224|Proteobacteria,2U17A@28211|Alphaproteobacteria,4NBJF@97050|Ruegeria	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_359273_1	706587.Desti_5263	5.64e-07	50.8	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,42MPW@68525|delta/epsilon subdivisions,2WN96@28221|Deltaproteobacteria,2MRIF@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_359273_2	56780.SYN_00987	1.94e-28	105.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria,2MQN2@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_907346_1	1040982.AXAL01000035_gene78	0.000817	43.1	COG4957@1|root,COG4957@2|Bacteria,1RGUW@1224|Proteobacteria,2U99M@28211|Alphaproteobacteria,43PQJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	ROS/MUCR transcriptional regulator protein	-	-	-	-	-	-	-	-	-	-	-	-	ROS_MUCR
k59_398502_1	207954.MED92_05039	4.57e-84	264.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1XIPI@135619|Oceanospirillales	135619|Oceanospirillales	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_907363_1	745014.OMB55_00016230	2.09e-38	133.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	stringent starvation protein b	sspB	GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
k59_907378_1	1121405.dsmv_2218	3.16e-26	107.0	COG1960@1|root,COG1960@2|Bacteria,1NU73@1224|Proteobacteria,42Z96@68525|delta/epsilon subdivisions,2WTTK@28221|Deltaproteobacteria,2MN2J@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_907378_2	398511.BpOF4_00765	8.03e-14	65.9	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,4HNIZ@91061|Bacilli,1ZJ4F@1386|Bacillus	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
k59_476536_1	314285.KT71_04825	3.48e-73	238.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1J8EU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_1182150_1	87626.PTD2_02306	2.39e-40	149.0	COG2807@1|root,COG2807@2|Bacteria,1NXQ2@1224|Proteobacteria,1RXXM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_398526_1	933262.AXAM01000040_gene1222	1.86e-59	196.0	COG4123@1|root,COG4123@2|Bacteria,1MXEQ@1224|Proteobacteria,42SAA@68525|delta/epsilon subdivisions,2WPCM@28221|Deltaproteobacteria,2MJTD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Methyltransferase small domain	-	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
k59_594142_1	1122137.AQXF01000004_gene1752	2.5e-06	54.3	COG1073@1|root,COG1073@2|Bacteria,1RC0W@1224|Proteobacteria,2U6C5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	FG	alpha, beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,Abhydrolase_6,HIT,Hydrolase_4
k59_594153_1	570952.ATVH01000013_gene3073	8.75e-71	228.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2TUPG@28211|Alphaproteobacteria,2JQS8@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_594155_1	204669.Acid345_4384	2.25e-21	94.7	COG3547@1|root,COG3547@2|Bacteria,3Y5SI@57723|Acidobacteria,2JNJP@204432|Acidobacteriia	204432|Acidobacteriia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_45364_1	290400.Jann_3107	1.78e-84	256.0	COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,2U7CA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_398542_1	1381751.JAJB01000070_gene355	5.45e-62	202.0	COG0300@1|root,COG0300@2|Bacteria,2IAR1@201174|Actinobacteria,4FAUX@85019|Brevibacteriaceae	201174|Actinobacteria	S	KR domain	-	-	1.1.1.105	ko:K07124,ko:K15734	ko00830,map00830	-	R02124	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
k59_750793_1	9555.ENSPANP00000008693	1.29e-112	333.0	KOG2945@1|root,KOG2945@2759|Eukaryota,38FFW@33154|Opisthokonta,3BEJZ@33208|Metazoa,3CXCU@33213|Bilateria,48A62@7711|Chordata,48ZZU@7742|Vertebrata,3J9JB@40674|Mammalia,35HFV@314146|Euarchontoglires,4MG6X@9443|Primates,366HF@314294|Cercopithecoidea	33208|Metazoa	S	SERPINE1 mRNA binding protein 1	SERBP1	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005700,GO:0005701,GO:0005703,GO:0005737,GO:0005829,GO:0006325,GO:0006355,GO:0006464,GO:0006479,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008213,GO:0009889,GO:0009892,GO:0009894,GO:0009987,GO:0010369,GO:0010468,GO:0010556,GO:0010605,GO:0010608,GO:0010629,GO:0016043,GO:0016246,GO:0016441,GO:0016442,GO:0016458,GO:0016569,GO:0016570,GO:0016571,GO:0018022,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0031047,GO:0031323,GO:0031326,GO:0031329,GO:0031332,GO:0031935,GO:0032259,GO:0032991,GO:0033043,GO:0033044,GO:0034968,GO:0035194,GO:0036211,GO:0040029,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043414,GO:0043487,GO:0043488,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0051276,GO:0051567,GO:0060255,GO:0060968,GO:0061013,GO:0061647,GO:0065007,GO:0065008,GO:0070828,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0098687,GO:1901363,GO:1901564,GO:1902275,GO:1903311,GO:1903506,GO:1990904,GO:2000112,GO:2001141	-	ko:K13199	-	-	-	-	ko00000,ko03041	-	-	-	HABP4_PAI-RBP1,IHABP4_N
k59_124255_1	1123070.KB899252_gene926	3.8e-55	187.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	MA20_04810	-	3.5.1.82	ko:K01461	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_3
k59_672504_1	335543.Sfum_1940	1.71e-69	214.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42R5T@68525|delta/epsilon subdivisions,2WMVQ@28221|Deltaproteobacteria,2MRW5@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
k59_241542_1	177437.HRM2_01760	6.21e-119	352.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2MJ8E@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Domain of unknown function (DUF3333)	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
k59_633647_1	948565.AFFP02000008_gene1702	9.65e-27	100.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1Y904@135625|Pasteurellales	135625|Pasteurellales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
k59_633647_2	545264.KB898750_gene295	2.98e-56	189.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1WVYW@135613|Chromatiales	135613|Chromatiales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_476652_1	472759.Nhal_3504	7.17e-38	140.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1WX73@135613|Chromatiales	135613|Chromatiales	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N,Kdo
k59_868218_1	1500259.JQLD01000002_gene3086	6.86e-46	166.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4BAVP@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16
k59_85450_1	1121405.dsmv_3358	2.06e-41	153.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42P1P@68525|delta/epsilon subdivisions,2WJ99@28221|Deltaproteobacteria,2MJA4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TAT_signal,TPR_16,TPR_19
k59_202127_1	357804.Ping_1395	8.65e-34	129.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,2QICJ@267894|Psychromonadaceae	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_516030_1	589865.DaAHT2_2564	1.87e-38	147.0	COG0784@1|root,COG5000@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BSJ@68525|delta/epsilon subdivisions,2X73B@28221|Deltaproteobacteria,2MI6A@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_359513_1	1121918.ARWE01000001_gene2346	2.84e-77	239.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MR6@68525|delta/epsilon subdivisions,2WITP@28221|Deltaproteobacteria,43SYR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_359513_2	1232437.KL662073_gene1725	3.08e-132	397.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria,2MIMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_85473_1	177437.HRM2_07450	6.67e-67	220.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MMNB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
k59_124338_1	1125863.JAFN01000001_gene2805	4e-63	209.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,42NWZ@68525|delta/epsilon subdivisions,2WJU7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM TrkA-N domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_711459_1	644282.Deba_0055	2.64e-10	63.9	COG0589@1|root,COG0589@2|Bacteria,1REA3@1224|Proteobacteria,42RXY@68525|delta/epsilon subdivisions,2WNM6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_359551_1	667632.KB890172_gene3950	1.67e-68	216.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2VIXS@28216|Betaproteobacteria,1K60B@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	gluconate 5-dehydrogenase	kduD	-	1.1.1.47,1.1.1.69	ko:K00034,ko:K00046	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
k59_359582_1	1453501.JELR01000002_gene166	5.54e-54	186.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464NX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_946787_1	1499967.BAYZ01000178_gene4647	2.87e-31	125.0	COG0497@1|root,COG0497@2|Bacteria,2NNUS@2323|unclassified Bacteria	2|Bacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03631,ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
k59_280755_1	1499967.BAYZ01000019_gene6299	1.65e-61	194.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_280755_2	706587.Desti_4287	7.14e-26	103.0	COG1413@1|root,COG1413@2|Bacteria,1R6G4@1224|Proteobacteria,42T2X@68525|delta/epsilon subdivisions,2WPNC@28221|Deltaproteobacteria,2MRRI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_EZ
k59_6779_1	177437.HRM2_24470	8.22e-121	357.0	COG2357@1|root,COG2357@2|Bacteria,1RCHE@1224|Proteobacteria,42PPK@68525|delta/epsilon subdivisions,2WJBS@28221|Deltaproteobacteria,2MHSG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
k59_986446_1	287.DR97_94	4.9e-09	56.2	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,1YE8S@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
k59_986446_2	637905.SVI_3353	6.72e-51	169.0	COG0652@1|root,COG0652@2|Bacteria,1REE3@1224|Proteobacteria,1S4BW@1236|Gammaproteobacteria,2QASH@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_1142731_1	9598.ENSPTRP00000006478	4.15e-309	845.0	COG0625@1|root,KOG1627@1|root,KOG0867@2759|Eukaryota,KOG1627@2759|Eukaryota,38CDH@33154|Opisthokonta,3BGGP@33208|Metazoa,3CR8K@33213|Bilateria,48063@7711|Chordata,48ZND@7742|Vertebrata,3J78S@40674|Mammalia,35KCR@314146|Euarchontoglires,4M6D5@9443|Primates,4N4H7@9604|Hominidae	33208|Metazoa	J	Elongation factor 1 gamma, conserved domain	EEF1G	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0004364,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051704,GO:0051707,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K03233	ko05134,map05134	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	EF1G,GST_C,GST_N
k59_280775_1	1216976.AX27061_0142	1.09e-33	126.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,2VS2S@28216|Betaproteobacteria,3T928@506|Alcaligenaceae	28216|Betaproteobacteria	F	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
k59_946827_1	1469245.JFBG01000001_gene538	9.01e-32	119.0	COG1073@1|root,COG1073@2|Bacteria,1N1WH@1224|Proteobacteria,1S9JK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF3530
k59_1142748_1	439235.Dalk_3253	1.18e-103	310.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2MHVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_1182342_1	243231.GSU2487	1.03e-23	100.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,42M16@68525|delta/epsilon subdivisions,2WM0V@28221|Deltaproteobacteria,43UMW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Amino acid kinase family	cpkA	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_711525_1	754436.JCM19237_1007	8.72e-26	109.0	COG0006@1|root,COG0006@2|Bacteria,1MVJK@1224|Proteobacteria,1T1D0@1236|Gammaproteobacteria,1XVYG@135623|Vibrionales	135623|Vibrionales	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
k59_6831_1	566466.NOR53_3413	1.39e-47	172.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
k59_986501_1	1502724.FF80_00530	3.7e-80	251.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1MVJX@1224|Proteobacteria,2TRR5@28211|Alphaproteobacteria,3N63Z@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobL	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	PCMT,TP_methylase
k59_711545_1	555779.Dthio_PD0164	2.3e-12	66.6	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,42N2X@68525|delta/epsilon subdivisions,2X7GJ@28221|Deltaproteobacteria,2MGSE@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Sigma-70 region 4 type 2	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_883849_1	990073.ATHU01000001_gene1007	1.97e-10	65.1	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2YMV8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_883861_1	550540.Fbal_1886	1.16e-48	170.0	COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,1RP9M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_570248_1	911045.PSE_1520	9.79e-64	203.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U7TT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	UPF0056 inner membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_299028_1	765912.Thimo_0344	1.08e-50	174.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales	135613|Chromatiales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_964855_1	977880.RALTA_B2273	1.56e-39	152.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,1JZPD@119060|Burkholderiaceae	28216|Betaproteobacteria	M	surface antigen variable number repeat protein	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
k59_494414_1	43179.ENSSTOP00000003257	5.27e-109	320.0	KOG2190@1|root,KOG2190@2759|Eukaryota,38G1X@33154|Opisthokonta,3BB3H@33208|Metazoa,3CSGT@33213|Bilateria,481Z0@7711|Chordata,48W31@7742|Vertebrata,3J8Y0@40674|Mammalia,35BGS@314146|Euarchontoglires,4PXTR@9989|Rodentia	33208|Metazoa	A	KH domain	PCBP2	GO:0000381,GO:0002682,GO:0002683,GO:0002697,GO:0002698,GO:0002831,GO:0002832,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006508,GO:0006511,GO:0006807,GO:0007610,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009266,GO:0009628,GO:0009987,GO:0010468,GO:0010498,GO:0016032,GO:0019058,GO:0019079,GO:0019080,GO:0019081,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0019941,GO:0030163,GO:0031323,GO:0031347,GO:0031348,GO:0031625,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0039694,GO:0040040,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043484,GO:0043632,GO:0043900,GO:0043901,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0048024,GO:0048519,GO:0048583,GO:0048585,GO:0050684,GO:0050687,GO:0050688,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051603,GO:0051704,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0075522,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1903311,GO:1990829	-	ko:K13162,ko:K21444	ko04216,map04216	-	-	-	ko00000,ko00001,ko03019,ko03041	-	-	-	KH_1
k59_259696_1	176280.SE_0856	1.11e-06	56.2	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,4GXGR@90964|Staphylococcaceae	91061|Bacilli	M	penicillin-binding protein	pbpX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
k59_924260_1	1121440.AUMA01000003_gene2832	2.49e-25	100.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,42NVB@68525|delta/epsilon subdivisions,2WK6R@28221|Deltaproteobacteria,2M88C@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_1242723_1	1121405.dsmv_1454	1.79e-117	363.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MHRG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_23643_1	933262.AXAM01000023_gene658	7.98e-89	291.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MI79@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_62463_2	1120941.AUBL01000010_gene420	4.37e-23	95.9	COG2078@1|root,COG2078@2|Bacteria,2ISCW@201174|Actinobacteria,4D5I2@85005|Actinomycetales	201174|Actinobacteria	S	AMMECR1	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
k59_964923_1	439235.Dalk_2830	5.97e-35	135.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1R7WZ@1224|Proteobacteria,42Q3R@68525|delta/epsilon subdivisions,2WM5A@28221|Deltaproteobacteria,2MIDF@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SSF,SpoIIE
k59_572546_1	700598.Niako_1259	4.33e-90	293.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,4NF4F@976|Bacteroidetes,1IPIS@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_846922_1	1121405.dsmv_3138	1.08e-95	307.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MIBK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_1242767_1	272560.BPSS2081	9.8e-31	124.0	COG3345@1|root,COG3345@2|Bacteria,1MWTQ@1224|Proteobacteria,2VPKQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Glycosyl hydrolase family 36 N-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
k59_536168_1	9606.ENSP00000317992	2.13e-145	429.0	COG5604@1|root,KOG2256@2759|Eukaryota,38F9K@33154|Opisthokonta,3B9JQ@33208|Metazoa,3CTUJ@33213|Bilateria,48CEN@7711|Chordata,48WCT@7742|Vertebrata,3JC3G@40674|Mammalia,35JHU@314146|Euarchontoglires,4M7PR@9443|Primates,4MU4T@9604|Hominidae	33208|Metazoa	K	Noc2p family	NOC2L	GO:0000122,GO:0002039,GO:0002902,GO:0002903,GO:0003674,GO:0003682,GO:0003712,GO:0003714,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0006323,GO:0006325,GO:0006333,GO:0006355,GO:0006357,GO:0006996,GO:0008134,GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010639,GO:0010646,GO:0010648,GO:0010941,GO:0016043,GO:0019219,GO:0019222,GO:0022607,GO:0022613,GO:0023051,GO:0023057,GO:0030684,GO:0030686,GO:0030687,GO:0030689,GO:0030690,GO:0030691,GO:0031056,GO:0031057,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031399,GO:0031400,GO:0031491,GO:0031493,GO:0031497,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032991,GO:0033043,GO:0033044,GO:0034644,GO:0035065,GO:0035067,GO:0042254,GO:0042273,GO:0042393,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051276,GO:0051716,GO:0060255,GO:0060548,GO:0065007,GO:0070013,GO:0070228,GO:0070229,GO:0070491,GO:0071103,GO:0071214,GO:0071478,GO:0071482,GO:0071840,GO:0080090,GO:0104004,GO:0140110,GO:1901796,GO:1901983,GO:1901984,GO:1902275,GO:1902531,GO:1902532,GO:1902679,GO:1903506,GO:1903507,GO:1905268,GO:1990904,GO:2000106,GO:2000107,GO:2000112,GO:2000113,GO:2000756,GO:2000757,GO:2001141,GO:2001233,GO:2001234,GO:2001242,GO:2001243,GO:2001251	-	ko:K14833	-	-	-	-	ko00000,ko03009	-	-	-	Noc2
k59_846943_2	96561.Dole_0430	1.28e-25	99.8	COG3462@1|root,COG3462@2|Bacteria,1Q55M@1224|Proteobacteria,42WZ8@68525|delta/epsilon subdivisions,2WSP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
k59_846943_3	96561.Dole_0431	1.46e-06	49.7	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42MPR@68525|delta/epsilon subdivisions,2WNM3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Multicopper	cumA	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
k59_1045200_1	335543.Sfum_0929	2.5e-81	267.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_536186_1	1121937.AUHJ01000004_gene1087	2.22e-69	225.0	COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,1RQM5@1236|Gammaproteobacteria,465Q5@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Carboxypeptidase Taq (M32) metallopeptidase	mcar-1	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
k59_806605_1	926554.KI912671_gene275	9.13e-55	183.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta
k59_572602_1	1047013.AQSP01000106_gene1765	7.87e-55	183.0	COG1509@1|root,COG1509@2|Bacteria,2NNY6@2323|unclassified Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA	-	5.4.3.2,5.4.3.9	ko:K01843,ko:K19810,ko:K19814	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
k59_768427_1	1121937.AUHJ01000004_gene1080	4.21e-14	73.2	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,1S5IS@1236|Gammaproteobacteria,46B06@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_612285_1	335543.Sfum_0007	5.51e-123	366.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,2MQZD@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k59_494558_1	1408254.T458_08960	3.26e-59	216.0	COG1574@1|root,COG2366@1|root,COG1574@2|Bacteria,COG2366@2|Bacteria,1TT7I@1239|Firmicutes,4HAZ1@91061|Bacilli	91061|Bacilli	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_1121427_1	196490.AUEZ01000001_gene7513	3.34e-35	137.0	COG0651@1|root,COG0651@2|Bacteria,1QI9G@1224|Proteobacteria,2V9HG@28211|Alphaproteobacteria,3K44I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
k59_494565_1	1218108.KB908300_gene2503	3.57e-17	87.0	COG1524@1|root,COG1524@2|Bacteria,4NFFG@976|Bacteroidetes,1HX3P@117743|Flavobacteriia	976|Bacteroidetes	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phosphodiest
k59_103740_1	648757.Rvan_3264	1.75e-25	103.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria,3N65Y@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_103740_2	883080.HMPREF9697_02480	1.05e-41	144.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,3JSRB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_612307_1	994573.T472_0211705	5.67e-66	220.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,36G29@31979|Clostridiaceae	186801|Clostridia	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_1242872_1	994479.GL877878_gene2622	3.87e-59	205.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4DXNT@85010|Pseudonocardiales	201174|Actinobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_377376_1	438753.AZC_4367	3.71e-34	121.0	COG0599@1|root,COG0599@2|Bacteria,1RJU6@1224|Proteobacteria,2U5JQ@28211|Alphaproteobacteria,3EZZU@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Carboxymuconolactone decarboxylase family	MA20_20490	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
k59_455086_2	72664.XP_006404386.1	5.71e-09	57.4	KOG0126@1|root,KOG0126@2759|Eukaryota,37HZA@33090|Viridiplantae,3G9CC@35493|Streptophyta,3HNH3@3699|Brassicales	35493|Streptophyta	A	Zinc finger CCCH domain-containing protein	-	GO:0000375,GO:0000377,GO:0000398,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005686,GO:0006139,GO:0006396,GO:0006397,GO:0006403,GO:0006405,GO:0006406,GO:0006611,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0008104,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0015931,GO:0016070,GO:0016071,GO:0016604,GO:0016607,GO:0030532,GO:0031503,GO:0031974,GO:0031981,GO:0032991,GO:0033036,GO:0034613,GO:0034641,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0045184,GO:0046483,GO:0046907,GO:0050657,GO:0050658,GO:0051028,GO:0051168,GO:0051169,GO:0051179,GO:0051234,GO:0051236,GO:0051641,GO:0051649,GO:0070013,GO:0070274,GO:0070727,GO:0071011,GO:0071013,GO:0071166,GO:0071426,GO:0071427,GO:0071702,GO:0071704,GO:0071705,GO:0090304,GO:0097159,GO:0097525,GO:0120114,GO:1901360,GO:1901363,GO:1902494,GO:1990904	-	ko:K13107	-	-	-	-	ko00000,ko03041	-	-	-	RRM_1,zf-CCCH
k59_1199964_1	706587.Desti_1266	3.56e-91	280.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,42MPB@68525|delta/epsilon subdivisions,2WJUV@28221|Deltaproteobacteria,2MQZ7@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_299263_1	396588.Tgr7_0968	1.35e-55	191.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1WW15@135613|Chromatiales	135613|Chromatiales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
k59_337845_1	1205753.A989_18025	2.86e-17	91.3	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales	135614|Xanthomonadales	T	Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_768525_1	268747.E2PU08_BPPRS	1e-54	176.0	4QAUK@10239|Viruses,4QWEQ@35237|dsDNA viruses  no RNA stage,4QQ1Z@28883|Caudovirales,4QIJA@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1009441_1	331678.Cphamn1_1145	3.13e-20	94.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	int	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_377417_1	1144319.PMI16_01976	4.63e-11	68.2	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2WEZH@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_1121515_1	96561.Dole_2586	2.22e-93	294.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2MI69@213118|Desulfobacterales	28221|Deltaproteobacteria	D	DNA segregation ATPase, FtsK SpoIIIE family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_222938_1	1454202.PPBDW_140082___1	4.19e-90	276.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,1XV0G@135623|Vibrionales	135623|Vibrionales	F	carbamoyl-phosphate synthetase glutamine chain	carA	GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006139,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_847139_1	1333507.AUTQ01000154_gene4424	1.03e-106	316.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,2Q154@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	F	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	rimK	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_886447_2	998674.ATTE01000001_gene2728	1.43e-63	209.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,462TY@72273|Thiotrichales	72273|Thiotrichales	P	Phosphate ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,DUF3708
k59_1200024_2	247634.GPB2148_2772	1.13e-57	186.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1J61U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0043487,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0045935,GO:0046483,GO:0046700,GO:0046872,GO:0048518,GO:0048519,GO:0048522,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_1081500_1	246200.SPO3036	7.76e-98	304.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2TSM1@28211|Alphaproteobacteria,4ND2Q@97050|Ruegeria	28211|Alphaproteobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
k59_1009490_1	595536.ADVE02000001_gene1023	3.98e-21	86.3	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,36YDS@31993|Methylocystaceae	28211|Alphaproteobacteria	O	Chaperonin 10 Kd subunit	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_1009490_2	1121405.dsmv_2161	4.87e-76	243.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_421435_1	714961.BFZC1_23084	1.35e-114	342.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3IWPV@400634|Lysinibacillus	91061|Bacilli	C	Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes	acoD	-	-	ko:K00138	ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120	-	R00711	RC00047	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_847155_1	1232437.KL662058_gene3953	7.07e-20	88.6	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MIN8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_847155_2	357809.Cphy_3429	7.89e-05	48.1	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,221NY@1506553|Lachnoclostridium	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1200051_1	272123.Anacy_5275	7.64e-42	146.0	COG1662@1|root,COG3677@1|root,COG1662@2|Bacteria,COG3677@2|Bacteria,1G617@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM IS1 transposase	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1
k59_103887_1	350688.Clos_1421	2.42e-73	234.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,36ED0@31979|Clostridiaceae	186801|Clostridia	S	tigr00255	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
k59_768625_1	335543.Sfum_2063	1.07e-91	303.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MXBU@1224|Proteobacteria,42M59@68525|delta/epsilon subdivisions,2WIUK@28221|Deltaproteobacteria,2MR7V@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_223003_1	509190.Cseg_2871	1.44e-14	73.9	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2TT3P@28211|Alphaproteobacteria,2KGAR@204458|Caulobacterales	204458|Caulobacterales	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_223003_2	1122132.AQYH01000007_gene2115	3.27e-11	64.3	COG1434@1|root,COG1434@2|Bacteria,1RHMV@1224|Proteobacteria,2U957@28211|Alphaproteobacteria,4B7AZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	DUF218 domain	MA20_20455	-	-	-	-	-	-	-	-	-	-	-	DUF218
k59_23966_1	1123253.AUBD01000010_gene2213	3.94e-50	175.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1X4K0@135614|Xanthomonadales	135614|Xanthomonadales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_690761_1	1121440.AUMA01000006_gene1545	1.08e-59	199.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MR8@68525|delta/epsilon subdivisions,2WIUA@28221|Deltaproteobacteria,2MA08@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_181039_1	1121405.dsmv_0618	1.65e-99	307.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,42PSJ@68525|delta/epsilon subdivisions,2WJDD@28221|Deltaproteobacteria,2MHWQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	reductase, alpha subunit	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
k59_806858_1	1041142.ATTP01000008_gene6415	1.17e-49	178.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16
k59_650740_1	1121405.dsmv_3042	3e-65	210.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,43BP2@68525|delta/epsilon subdivisions,2WK8X@28221|Deltaproteobacteria,2MPHN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART molybdopterin oxidoreductase Fe4S4 region, NADH ubiquinone oxidoreductase, subunit G, iron-sulfur binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
k59_103976_1	1031711.RSPO_c01585	8.3e-09	61.6	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,1K20K@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
k59_1160729_1	395493.BegalDRAFT_0086	1.9e-150	468.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,460BV@72273|Thiotrichales	72273|Thiotrichales	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k59_1200159_2	983545.Glaag_2024	9.83e-66	216.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,46625@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	alkK	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
k59_886594_1	335543.Sfum_4102	1.37e-25	102.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2WJ7Q@28221|Deltaproteobacteria,2MQE4@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_886594_2	1206729.BAFZ01000077_gene1552	7.24e-24	99.0	COG0309@1|root,COG0309@2|Bacteria,2GJ7N@201174|Actinobacteria,4FTY3@85025|Nocardiaceae	201174|Actinobacteria	O	AIR synthase related protein, C-terminal domain	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
k59_1243107_1	305900.GV64_21950	1.16e-40	149.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XICI@135619|Oceanospirillales	135619|Oceanospirillales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04691,ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
k59_1081662_2	313628.LNTAR_00635	3.25e-18	85.5	COG1253@1|root,COG1253@2|Bacteria	2|Bacteria	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
k59_223154_1	375286.mma_0704	1.01e-58	195.0	COG5361@1|root,COG5361@2|Bacteria,1MWTW@1224|Proteobacteria,2VPV5@28216|Betaproteobacteria,477QZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_572916_1	1265505.ATUG01000002_gene1014	4.34e-28	111.0	28J96@1|root,2Z947@2|Bacteria,1R6TE@1224|Proteobacteria,42PZG@68525|delta/epsilon subdivisions,2WIKY@28221|Deltaproteobacteria,2MHY0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Oligopeptide transporter OPT superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_572916_2	1167006.UWK_01870	3.2e-53	183.0	28HQ2@1|root,2Z7XV@2|Bacteria,1P4Z7@1224|Proteobacteria,42NSG@68525|delta/epsilon subdivisions,2WJ6K@28221|Deltaproteobacteria,2MJCF@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_421637_1	290315.Clim_1812	1.53e-27	106.0	COG5456@1|root,COG5456@2|Bacteria	2|Bacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH,YtkA
k59_492260_1	519989.ECTPHS_13088	7.78e-81	246.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1WVYC@135613|Chromatiales	135613|Chromatiales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_688213_1	1280948.HY36_01145	7.87e-178	528.0	COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,2TSK9@28211|Alphaproteobacteria,43WCB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_21506_1	2340.JV46_16550	1.31e-88	274.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1J53B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Aminotransferase	hemL	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iUMNK88_1353.UMNK88_158	Aminotran_3
k59_138973_1	370438.PTH_2737	1.95e-72	244.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1043380_1	1322246.BN4_10182	2.18e-11	69.7	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2WNW9@28221|Deltaproteobacteria,2M9AK@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	GTP-binding signal recognition particle SRP54	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
k59_922229_1	1294273.roselon_00568	5.04e-72	233.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2TRQ2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
k59_492292_1	420324.KI911972_gene3031	4.63e-21	85.9	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2UD5E@28211|Alphaproteobacteria,1JV34@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_492292_2	876269.ARWA01000001_gene2144	1.96e-56	188.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2U2BQ@28211|Alphaproteobacteria,3N9KG@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
k59_335358_1	9606.ENSP00000477502	1.21e-142	436.0	KOG1948@1|root,KOG1948@2759|Eukaryota,38EKX@33154|Opisthokonta,3BBHT@33208|Metazoa,3CSTB@33213|Bilateria,4850W@7711|Chordata,48ZJ6@7742|Vertebrata,3J4VK@40674|Mammalia,35FU0@314146|Euarchontoglires,4M5PH@9443|Primates,4MVE2@9604|Hominidae	33208|Metazoa	O	carbohydrate binding	NOMO1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0012505,GO:0016020,GO:0031984,GO:0032991,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0098827	-	ko:K21988	-	-	-	-	ko00000,ko02000	1.A.17.4	-	-	CarboxypepD_reg,TMC
k59_178844_1	1230476.C207_03123	3.11e-63	201.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,3JUHS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
k59_688279_1	745014.OMB55_00006620	3.63e-62	211.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RR88@1236|Gammaproteobacteria,1J5WK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EU	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_533104_1	882378.RBRH_02726	4.97e-85	264.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,1K11D@119060|Burkholderiaceae	28216|Betaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_570418_1	1286632.P278_31290	2.98e-38	145.0	28HMZ@1|root,2Z7WD@2|Bacteria,4P095@976|Bacteroidetes,1I89H@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_1043429_1	1089550.ATTH01000001_gene1532	2.03e-08	60.8	COG1462@1|root,COG1462@2|Bacteria	2|Bacteria	M	curli production assembly transport component CsgG	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	CsgG,FlgT_C
k59_1006466_1	87626.PTD2_12614	8.48e-09	61.6	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1QU0Y@1224|Proteobacteria,1T1KC@1236|Gammaproteobacteria,2Q5GI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_688291_1	1318628.MARLIPOL_01200	2.37e-37	144.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,4640F@72275|Alteromonadaceae	1236|Gammaproteobacteria	GM	nucleoside-diphosphate sugar epimerases	wbpM	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_219740_1	1134912.AJTV01000004_gene923	1.82e-76	242.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,36YWY@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_60472_1	740709.A10D4_11314	1.02e-68	223.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,2QG08@267893|Idiomarinaceae	1236|Gammaproteobacteria	U	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
k59_962701_1	690850.Desaf_3699	4.74e-76	241.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42N47@68525|delta/epsilon subdivisions,2WIKZ@28221|Deltaproteobacteria,2M8JX@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	qrcD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_21597_1	1121405.dsmv_1745	3.77e-61	201.0	COG0620@1|root,COG0620@2|Bacteria,1R6KI@1224|Proteobacteria,42PCN@68525|delta/epsilon subdivisions,2WKT3@28221|Deltaproteobacteria,2MID3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_533148_1	643562.Daes_0039	3.55e-45	155.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,2M9J5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
k59_1240744_1	1121403.AUCV01000002_gene540	5.03e-93	280.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MR6@68525|delta/epsilon subdivisions,2WITP@28221|Deltaproteobacteria,2MHTE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_492363_1	413816.BBJP01000001_gene11	3.08e-58	195.0	COG4666@1|root,arCOG01906@2157|Archaea,2XVCC@28890|Euryarchaeota,23U3S@183963|Halobacteria	183963|Halobacteria	S	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_219758_1	580327.Tthe_0691	3.84e-29	119.0	COG4584@1|root,COG4584@2|Bacteria,1UW0T@1239|Firmicutes,24AQA@186801|Clostridia,42FWX@68295|Thermoanaerobacterales	186801|Clostridia	L	COGs COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Sigma70_r4_2,rve
k59_688317_1	864069.MicloDRAFT_00044590	3.67e-28	116.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,1JUC6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
k59_922319_1	697303.Thewi_1822	3.99e-17	76.6	COG1342@1|root,COG1342@2|Bacteria,1V5RE@1239|Firmicutes,25CFP@186801|Clostridia,42GP4@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the UPF0251 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
k59_418279_1	571166.KI421509_gene4104	2.38e-30	121.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2U4XB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE,MgtE_N
k59_375075_1	10160.XP_004634291.1	1.47e-59	201.0	COG1498@1|root,KOG2573@2759|Eukaryota,38D7R@33154|Opisthokonta,3BA5G@33208|Metazoa,3CZ6W@33213|Bilateria,486MT@7711|Chordata,48Y8T@7742|Vertebrata,3J28G@40674|Mammalia,35FGR@314146|Euarchontoglires,4PU46@9989|Rodentia	33208|Metazoa	AJ	Nucleolar protein 56	NOP56	GO:0000154,GO:0001650,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005732,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0019899,GO:0022613,GO:0030515,GO:0030684,GO:0031428,GO:0031974,GO:0031981,GO:0032040,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0070761,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990226,GO:1990904	-	ko:K14564	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	NOP5NT,Nop
k59_219776_1	713586.KB900538_gene20	5.77e-80	248.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,1RQ9W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	to Escherichia coli transposase for insertion sequence element IS21 IstA SW ISTA_ECOLI (P15025) (390 aa) fasta scores E() 3e-27, 33.1 id in 329 aa. Identical to the previously sequenced Yersinia pestis,Yersinia pseudotuberculosis and Escherichia coli pesticin plasmid insertion sequence transposase Y1055 TR P74993 (EMBL U59875) (340 aa) fasta scores E() 0, 100.0 id in 340 aa	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,HTH_7,rve
k59_533182_2	1550073.JROH01000048_gene2997	5.66e-23	99.4	COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,2TSUM@28211|Alphaproteobacteria,2K2K8@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_804619_1	1380358.JADJ01000003_gene4588	3.97e-05	49.3	COG0454@1|root,COG0456@2|Bacteria,1MYN8@1224|Proteobacteria,1S8BW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
k59_139081_1	1249997.JHZW01000002_gene841	2.13e-66	218.0	COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,1HX3S@117743|Flavobacteriia,2PH41@252356|Maribacter	976|Bacteroidetes	J	GAD domain	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_610327_1	935567.JAES01000051_gene326	9.9e-14	68.6	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,1X40M@135614|Xanthomonadales	135614|Xanthomonadales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
k59_610327_2	1234364.AMSF01000086_gene2850	3.64e-88	270.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1X3B7@135614|Xanthomonadales	135614|Xanthomonadales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_296999_2	1120983.KB894571_gene2178	2.96e-06	50.1	COG3247@1|root,COG3247@2|Bacteria,1RFIH@1224|Proteobacteria,2VBS3@28211|Alphaproteobacteria,1JQJX@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
k59_688347_1	1232437.KL661955_gene2363	1.89e-57	191.0	28MQN@1|root,2ZAZG@2|Bacteria,1MVVQ@1224|Proteobacteria,42MMM@68525|delta/epsilon subdivisions,2WKA1@28221|Deltaproteobacteria,2MHKP@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1119263_1	933262.AXAM01000010_gene1402	1.63e-83	256.0	COG0484@1|root,COG0705@1|root,COG0484@2|Bacteria,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2MI6P@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
k59_335490_1	717785.HYPMC_4175	5.95e-74	250.0	COG3087@1|root,COG5001@1|root,COG3087@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3N644@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	MA20_18100	-	3.1.4.52	ko:K13245	ko04112,map04112	-	R08991	RC00296	ko00000,ko00001,ko01000	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,EAL,GGDEF,PAS_3
k59_139122_1	313628.LNTAR_23894	3.38e-70	235.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_962777_1	177437.HRM2_05400	1.89e-98	296.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,42PDT@68525|delta/epsilon subdivisions,2WKER@28221|Deltaproteobacteria,2MIIP@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
k59_21676_1	1123504.JQKD01000049_gene2980	3.44e-20	90.5	COG2175@1|root,COG2175@2|Bacteria,1MVI6@1224|Proteobacteria	1224|Proteobacteria	Q	taurine catabolism dioxygenase	-	-	1.14.11.17	ko:K03119,ko:K06912	ko00361,ko00430,ko00920,ko01120,ko01220,map00361,map00430,map00920,map01120,map01220	-	R05320,R05419,R05493	RC01331,RC01371,RC01372	ko00000,ko00001,ko01000	-	-	-	TauD
k59_727649_1	706587.Desti_0410	6.96e-26	104.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,42QBT@68525|delta/epsilon subdivisions,2WJK6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_178975_1	7918.ENSLOCP00000021097	5.52e-07	57.8	COG3119@1|root,KOG3731@2759|Eukaryota,38E91@33154|Opisthokonta,3BCUU@33208|Metazoa,3D1EQ@33213|Bilateria,4827H@7711|Chordata,4908D@7742|Vertebrata,4A1BM@7898|Actinopterygii	33208|Metazoa	G	Belongs to the sulfatase family	GNS	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008449,GO:0008484,GO:0009056,GO:0009057,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0030203,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042339,GO:0042340,GO:0042582,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044422,GO:0044424,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510,GO:1904813	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
k59_1158279_1	933262.AXAM01000001_gene336	1.79e-81	258.0	COG1960@1|root,COG1960@2|Bacteria,1NU73@1224|Proteobacteria,42Z96@68525|delta/epsilon subdivisions,2WTTK@28221|Deltaproteobacteria,2MN2J@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_1079249_1	999141.GME_13350	5.95e-12	63.9	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1XI8V@135619|Oceanospirillales	135619|Oceanospirillales	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_1079249_2	999141.GME_13345	2.43e-76	233.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1XH61@135619|Oceanospirillales	135619|Oceanospirillales	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_335583_1	185453.XP_006866384.1	4.69e-128	368.0	KOG3174@1|root,KOG3174@2759|Eukaryota,38E7G@33154|Opisthokonta,3BCT8@33208|Metazoa,3CW5Q@33213|Bilateria,482GF@7711|Chordata,48ZIU@7742|Vertebrata,3JBNN@40674|Mammalia,352MK@311790|Afrotheria	33208|Metazoa	Z	F-actin capping protein, beta subunit	CAPZB	GO:0000003,GO:0000578,GO:0000902,GO:0001667,GO:0001932,GO:0001933,GO:0002064,GO:0002065,GO:0002066,GO:0002376,GO:0002478,GO:0002495,GO:0002504,GO:0003006,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005869,GO:0005875,GO:0005884,GO:0005903,GO:0005911,GO:0005938,GO:0006810,GO:0006888,GO:0006928,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007018,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007300,GO:0007303,GO:0007389,GO:0007399,GO:0007444,GO:0007596,GO:0007599,GO:0008064,GO:0008092,GO:0008150,GO:0008290,GO:0008582,GO:0009611,GO:0009653,GO:0009790,GO:0009798,GO:0009880,GO:0009888,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010563,GO:0010591,GO:0010605,GO:0010631,GO:0010639,GO:0010646,GO:0010648,GO:0014704,GO:0015629,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016192,GO:0016477,GO:0016482,GO:0019220,GO:0019222,GO:0019882,GO:0019884,GO:0019886,GO:0019953,GO:0022008,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023057,GO:0030016,GO:0030017,GO:0030018,GO:0030027,GO:0030029,GO:0030030,GO:0030031,GO:0030032,GO:0030036,GO:0030054,GO:0030154,GO:0030182,GO:0030425,GO:0030707,GO:0030832,GO:0030833,GO:0030834,GO:0030835,GO:0030837,GO:0030855,GO:0030863,GO:0031110,GO:0031111,GO:0031113,GO:0031115,GO:0031175,GO:0031252,GO:0031323,GO:0031324,GO:0031333,GO:0031344,GO:0031345,GO:0031399,GO:0031400,GO:0031674,GO:0032268,GO:0032269,GO:0032271,GO:0032272,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032872,GO:0032873,GO:0032886,GO:0032956,GO:0032970,GO:0032989,GO:0032991,GO:0033011,GO:0033043,GO:0033150,GO:0035220,GO:0035295,GO:0036477,GO:0040008,GO:0040011,GO:0042060,GO:0042325,GO:0042326,GO:0042692,GO:0042995,GO:0043005,GO:0043025,GO:0043197,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043242,GO:0043244,GO:0043254,GO:0043292,GO:0043408,GO:0043409,GO:0044085,GO:0044087,GO:0044089,GO:0044291,GO:0044297,GO:0044309,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044449,GO:0044456,GO:0044463,GO:0044464,GO:0044703,GO:0044877,GO:0045202,GO:0045887,GO:0045927,GO:0045936,GO:0046328,GO:0046329,GO:0046907,GO:0046982,GO:0046983,GO:0048002,GO:0048193,GO:0048468,GO:0048471,GO:0048477,GO:0048487,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048609,GO:0048638,GO:0048639,GO:0048666,GO:0048699,GO:0048731,GO:0048747,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050817,GO:0050878,GO:0050896,GO:0051015,GO:0051016,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051146,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051489,GO:0051490,GO:0051493,GO:0051494,GO:0051641,GO:0051649,GO:0051674,GO:0051693,GO:0051704,GO:0051960,GO:0051962,GO:0051963,GO:0051965,GO:0055001,GO:0055002,GO:0060255,GO:0060429,GO:0060491,GO:0061061,GO:0065007,GO:0065008,GO:0070302,GO:0070303,GO:0070507,GO:0071203,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0090036,GO:0090066,GO:0090130,GO:0090132,GO:0097435,GO:0097447,GO:0097458,GO:0097581,GO:0098794,GO:0098862,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099568,GO:0110053,GO:0120025,GO:0120031,GO:0120032,GO:0120033,GO:0120035,GO:0120036,GO:0120038,GO:1901879,GO:1901880,GO:1902531,GO:1902532,GO:1902743,GO:1902903,GO:1902904,GO:1904396,GO:1904398,GO:2000026	-	ko:K10365	ko04144,map04144	-	-	-	ko00000,ko00001,ko04131,ko04147,ko04812	-	-	-	F_actin_cap_B
k59_536704_2	1248916.ANFY01000003_gene973	7.66e-11	67.0	COG5640@1|root,COG5640@2|Bacteria,1R56C@1224|Proteobacteria,2UQZB@28211|Alphaproteobacteria,2K9F3@204457|Sphingomonadales	204457|Sphingomonadales	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
k59_421671_1	1150469.RSPPHO_01272	9.49e-28	113.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2JPGU@204441|Rhodospirillales	204441|Rhodospirillales	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.96	ko:K16871	ko00250,ko00650,ko01100,ko01120,map00250,map00650,map01100,map01120	M00027	R10178	RC00008,RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_3
k59_494880_2	1333523.L593_11705	1.56e-49	174.0	COG5441@1|root,arCOG09140@2157|Archaea,2XVEE@28890|Euryarchaeota,23UDV@183963|Halobacteria	183963|Halobacteria	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
k59_612598_1	469381.Dpep_1918	4.26e-38	145.0	COG1032@1|root,COG1032@2|Bacteria,3TA92@508458|Synergistetes	508458|Synergistetes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_494888_1	1322246.BN4_11755	1.87e-92	287.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2WK1D@28221|Deltaproteobacteria,2M9K4@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_494901_1	1121015.N789_05515	7.95e-36	127.0	COG2259@1|root,COG2259@2|Bacteria,1RHIY@1224|Proteobacteria,1SIZV@1236|Gammaproteobacteria,1X7C9@135614|Xanthomonadales	135614|Xanthomonadales	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
k59_494901_2	247633.GP2143_08589	2.52e-16	77.8	COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,1J6PK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09929	-	-	-	-	ko00000	-	-	-	DUF2063
k59_338125_1	1265505.ATUG01000002_gene1616	1.62e-117	367.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MIN8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_768819_1	234267.Acid_3270	9.39e-10	59.7	COG1858@1|root,COG1858@2|Bacteria,3Y6Q9@57723|Acidobacteria	57723|Acidobacteria	C	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
k59_924725_2	1267005.KB911258_gene361	2.14e-30	117.0	COG5436@1|root,COG5436@2|Bacteria,1PJY8@1224|Proteobacteria,2VCV8@28211|Alphaproteobacteria,3N7FH@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_847369_1	293826.Amet_3686	3.42e-09	63.5	COG1388@1|root,COG1388@2|Bacteria,1VEKE@1239|Firmicutes,24TUQ@186801|Clostridia,36MQK@31979|Clostridiaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_1200260_1	1394178.AWOO02000036_gene8915	6.77e-17	83.6	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4EPNF@85012|Streptosporangiales	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k59_650869_1	498211.CJA_2467	1.34e-34	130.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1FGYP@10|Cellvibrio	1236|Gammaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iUTI89_1310.UTI89_C0210	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_690918_1	1163617.SCD_n02368	1.5e-94	292.0	COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,2VQU4@28216|Betaproteobacteria	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_455402_1	936455.KI421499_gene1919	7.96e-13	73.9	COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,2U9KD@28211|Alphaproteobacteria,3JQYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Phosphate-selective porin O and P	oprO	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
k59_1200275_1	930169.B5T_04373	2.38e-63	214.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1XIU4@135619|Oceanospirillales	135619|Oceanospirillales	L	Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_806994_1	1231057.AMGD01000003_gene2227	1.6e-50	170.0	COG0596@1|root,COG0596@2|Bacteria,1UJJZ@1239|Firmicutes,4ITAM@91061|Bacilli,26CZI@186818|Planococcaceae	91061|Bacilli	S	Releases the N-terminal proline from various substrates	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_1045576_1	10141.ENSCPOP00000006432	1.4e-127	379.0	COG0513@1|root,KOG0331@2759|Eukaryota,38D0V@33154|Opisthokonta,3BCQC@33208|Metazoa,3CTK2@33213|Bilateria,48560@7711|Chordata,48XRJ@7742|Vertebrata,3J56E@40674|Mammalia,35EKW@314146|Euarchontoglires,4PTTP@9989|Rodentia	33208|Metazoa	A	P68HR (NUC004) repeat	DDX5	GO:0000122,GO:0000375,GO:0000377,GO:0000380,GO:0000381,GO:0000398,GO:0000956,GO:0001837,GO:0002376,GO:0002682,GO:0002697,GO:0002831,GO:0003674,GO:0003676,GO:0003682,GO:0003712,GO:0003723,GO:0003724,GO:0003729,GO:0003730,GO:0003824,GO:0004004,GO:0004386,GO:0005102,GO:0005488,GO:0005515,GO:0005516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005694,GO:0005700,GO:0005703,GO:0005730,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006396,GO:0006397,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006915,GO:0006955,GO:0006959,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007275,GO:0007623,GO:0008026,GO:0008134,GO:0008150,GO:0008152,GO:0008186,GO:0008219,GO:0008380,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009299,GO:0009605,GO:0009607,GO:0009719,GO:0009725,GO:0009755,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0012501,GO:0014070,GO:0016049,GO:0016070,GO:0016071,GO:0016202,GO:0016246,GO:0016441,GO:0016458,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019730,GO:0019899,GO:0019904,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030278,GO:0030509,GO:0030518,GO:0030520,GO:0030521,GO:0030522,GO:0031047,GO:0031050,GO:0031054,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031347,GO:0031974,GO:0031981,GO:0032101,GO:0032386,GO:0032501,GO:0032502,GO:0032774,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0033143,GO:0033157,GO:0033158,GO:0033993,GO:0034470,GO:0034641,GO:0034645,GO:0034654,GO:0034655,GO:0034660,GO:0035194,GO:0035195,GO:0035196,GO:0035257,GO:0035258,GO:0035500,GO:0035556,GO:0035770,GO:0036002,GO:0040007,GO:0040029,GO:0042221,GO:0042306,GO:0042623,GO:0043021,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043331,GO:0043401,GO:0043484,GO:0043516,GO:0043517,GO:0043900,GO:0043903,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0044877,GO:0045069,GO:0045445,GO:0045595,GO:0045667,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046332,GO:0046483,GO:0046700,GO:0046822,GO:0048024,GO:0048306,GO:0048511,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048634,GO:0048641,GO:0048731,GO:0048762,GO:0048856,GO:0048869,GO:0050681,GO:0050684,GO:0050688,GO:0050789,GO:0050792,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051172,GO:0051173,GO:0051223,GO:0051239,GO:0051252,GO:0051253,GO:0051254,GO:0051427,GO:0051704,GO:0051707,GO:0051716,GO:0060147,GO:0060148,GO:0060255,GO:0060341,GO:0060485,GO:0060765,GO:0060964,GO:0060966,GO:0060968,GO:0061061,GO:0061614,GO:0065007,GO:0070013,GO:0070035,GO:0070201,GO:0070412,GO:0070848,GO:0070878,GO:0070887,GO:0070918,GO:0070920,GO:0071013,GO:0071310,GO:0071359,GO:0071363,GO:0071383,GO:0071396,GO:0071407,GO:0071495,GO:0071704,GO:0071772,GO:0071773,GO:0072331,GO:0072332,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090304,GO:0097159,GO:0097190,GO:0097193,GO:0097659,GO:0098687,GO:0140098,GO:0140110,GO:1900180,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1901698,GO:1901699,GO:1901796,GO:1901798,GO:1901861,GO:1902494,GO:1902531,GO:1902533,GO:1902679,GO:1902680,GO:1903311,GO:1903506,GO:1903507,GO:1903508,GO:1903798,GO:1903800,GO:1903827,GO:1903900,GO:1904589,GO:1990841,GO:1990904,GO:2000026,GO:2000112,GO:2000113,GO:2000637,GO:2001014,GO:2001020,GO:2001022,GO:2001141	3.6.4.13	ko:K12823,ko:K13178	ko03040,ko05202,ko05205,map03040,map05202,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03041	-	-	-	DEAD,Helicase_C,P68HR
k59_747632_1	1120963.KB894500_gene100	3.13e-61	206.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oligopeptide transporter	-	-	-	-	-	-	-	-	-	-	-	-	OPT
k59_316495_1	656519.Halsa_0638	2.23e-24	106.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,3WAQC@53433|Halanaerobiales	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
k59_199108_1	1122603.ATVI01000005_gene3536	1.52e-47	161.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1X3F5@135614|Xanthomonadales	135614|Xanthomonadales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_826059_1	640512.BC1003_0664	2.15e-151	444.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2VZNG@28216|Betaproteobacteria,1K6IW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	similarity to GP 3192745	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_434103_1	395494.Galf_1995	2.15e-27	103.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,2VV65@28216|Betaproteobacteria,44WEX@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Thioesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
k59_434103_2	1137799.GZ78_06980	1.07e-16	74.7	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,1S4HQ@1236|Gammaproteobacteria,1XM0X@135619|Oceanospirillales	135619|Oceanospirillales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_1022229_1	1121405.dsmv_2145	1.22e-100	306.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2MI8B@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_551805_1	984262.SGRA_3334	5.39e-23	100.0	COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,1IPDJ@117747|Sphingobacteriia	976|Bacteroidetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_826067_1	525897.Dbac_1493	1.02e-23	94.4	2E4SV@1|root,32ZM7@2|Bacteria,1N8VN@1224|Proteobacteria,42VKR@68525|delta/epsilon subdivisions,2WS4C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
k59_355864_1	9361.ENSDNOP00000033543	2.63e-08	55.1	2D0NN@1|root,2SEU7@2759|Eukaryota,3A7A4@33154|Opisthokonta,3BTH0@33208|Metazoa,3D9BJ@33213|Bilateria,48FN9@7711|Chordata,49CMB@7742|Vertebrata,3JH4D@40674|Mammalia	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_355864_2	9823.ENSSSCP00000026019	6.29e-56	179.0	2D0NN@1|root,2SEU7@2759|Eukaryota,3A7A4@33154|Opisthokonta,3BTH0@33208|Metazoa,3D9BJ@33213|Bilateria,48FN9@7711|Chordata,49CMB@7742|Vertebrata,3JH4D@40674|Mammalia,4J9I7@91561|Cetartiodactyla	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_277498_1	706587.Desti_1474	4.25e-69	217.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42S61@68525|delta/epsilon subdivisions,2X5SR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k59_473426_1	309807.SRU_2232	6.52e-38	139.0	COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,1FJT5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Serine aminopeptidase, S33	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
k59_238217_1	766499.C357_18152	5.61e-125	383.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2TTPX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_434134_3	264402.Cagra.0007s0085.1.p	1.35e-18	82.0	COG0526@1|root,KOG0910@2759|Eukaryota,37UUM@33090|Viridiplantae,3GIDN@35493|Streptophyta,3HZMF@3699|Brassicales	35493|Streptophyta	O	Thioredoxin	-	GO:0003674,GO:0003824,GO:0004791,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006109,GO:0006950,GO:0006979,GO:0008047,GO:0008150,GO:0008152,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009636,GO:0009719,GO:0009725,GO:0009735,GO:0009941,GO:0009987,GO:0010033,GO:0015035,GO:0015036,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019222,GO:0019725,GO:0019904,GO:0030234,GO:0030312,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0033554,GO:0034357,GO:0034599,GO:0042221,GO:0042592,GO:0042651,GO:0043085,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044092,GO:0044093,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051716,GO:0055035,GO:0055114,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071944,GO:0080090,GO:0097237,GO:0098754,GO:0098772,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_3486_1	580332.Slit_0349	1.98e-36	138.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2VXAW@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_708314_1	1169143.KB911038_gene5936	2.66e-35	135.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2VI8J@28216|Betaproteobacteria,1K4EB@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
k59_42289_1	1158292.JPOE01000005_gene564	1.54e-10	62.8	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,1KKAB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	phosphatase	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
k59_42289_2	1198114.AciX9_1625	1.37e-05	49.3	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
k59_1100327_1	1038869.AXAN01000073_gene4633	1.05e-88	274.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2VIE4@28216|Betaproteobacteria,1K2M0@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_708323_1	268748.I3RYR3_BPPRP	2e-22	89.7	4QDR9@10239|Viruses,4QW63@35237|dsDNA viruses  no RNA stage,4QRVQ@28883|Caudovirales,4QP1T@10744|Podoviridae	10744|Podoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_708323_2	1273711.A0A096VKE2_9CAUD	2.96e-44	151.0	4QAM2@10239|Viruses,4QV3W@35237|dsDNA viruses  no RNA stage,4QPGK@28883|Caudovirales,4QNW0@10744|Podoviridae	10744|Podoviridae	S	exonuclease activity	-	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
k59_159988_1	870187.Thini_4244	1.74e-52	182.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,1RMCU@1236|Gammaproteobacteria,461XW@72273|Thiotrichales	72273|Thiotrichales	H	Cobyrinic acid A,C-diamide	-	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	CbiA,GATase_3
k59_1022313_1	675815.VOA_001131	2.45e-11	65.1	COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,1S2HE@1236|Gammaproteobacteria,1XVH5@135623|Vibrionales	135623|Vibrionales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_199195_1	82508.K1VSQ2	7.52e-20	85.9	COG1143@1|root,KOG3256@2759|Eukaryota,38HK4@33154|Opisthokonta,3NVE7@4751|Fungi,3UZJ8@5204|Basidiomycota,3VDWS@5234|Tremellales	4751|Fungi	C	4Fe-4S dicluster domain	NdufS8	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.6.5.3,1.6.99.3	ko:K03941	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1.6	-	-	Fer4
k59_669392_1	333138.LQ50_01220	2.66e-15	77.0	COG0651@1|root,COG0651@2|Bacteria,1TRAT@1239|Firmicutes,4HA10@91061|Bacilli,1ZB2A@1386|Bacillus	91061|Bacilli	CP	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali	mrpD	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
k59_669392_2	985762.SAGN_07933	1.01e-13	68.6	COG1006@1|root,COG1006@2|Bacteria,1V7CR@1239|Firmicutes,4HJHX@91061|Bacilli,4GZ3Z@90964|Staphylococcaceae	91061|Bacilli	P	Na( ) H( ) antiporter subunit	mrpC	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
k59_159995_1	38654.XP_006025989.1	8.62e-145	411.0	COG0638@1|root,KOG0183@2759|Eukaryota,38CHW@33154|Opisthokonta,3BD14@33208|Metazoa,3CT4Z@33213|Bilateria,47ZRG@7711|Chordata,495FT@7742|Vertebrata	33208|Metazoa	O	subunit alpha	PSMA7	GO:0000502,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005839,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016579,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0031974,GO:0031981,GO:0032991,GO:0036211,GO:0042802,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044464,GO:0045202,GO:0051603,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0098794,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K02731	ko03050,map03050	M00337,M00340	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051,ko04131	-	-	-	Proteasome,Proteasome_A_N
k59_355937_1	1121405.dsmv_1490	6.37e-45	162.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria,2MHWI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_551912_1	1123360.thalar_02885	7.07e-111	337.0	COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,2U068@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_3533_1	9606.ENSP00000358997	2.47e-120	362.0	COG0515@1|root,KOG1187@2759|Eukaryota,38G1T@33154|Opisthokonta,3BCM7@33208|Metazoa,3CUYA@33213|Bilateria,4826W@7711|Chordata,492AB@7742|Vertebrata,3JC9B@40674|Mammalia,35K7W@314146|Euarchontoglires,4M6ZY@9443|Primates,4MW13@9604|Hominidae	33208|Metazoa	T	Interleukin-1 receptor-associated kinase 1	IRAK1	GO:0000165,GO:0000187,GO:0000578,GO:0001817,GO:0001819,GO:0001932,GO:0001934,GO:0001959,GO:0002164,GO:0002218,GO:0002221,GO:0002224,GO:0002237,GO:0002253,GO:0002376,GO:0002520,GO:0002682,GO:0002684,GO:0002753,GO:0002755,GO:0002757,GO:0002758,GO:0002764,GO:0003002,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004704,GO:0005102,GO:0005126,GO:0005149,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005768,GO:0005811,GO:0005829,GO:0005886,GO:0005887,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007250,GO:0007254,GO:0007275,GO:0007352,GO:0007389,GO:0007525,GO:0007526,GO:0008063,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008284,GO:0009266,GO:0009408,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009628,GO:0009790,GO:0009791,GO:0009798,GO:0009799,GO:0009855,GO:0009880,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009950,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010008,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010874,GO:0010941,GO:0012501,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019219,GO:0019220,GO:0019221,GO:0019222,GO:0019538,GO:0019730,GO:0019732,GO:0019904,GO:0022607,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030162,GO:0030234,GO:0030522,GO:0031072,GO:0031090,GO:0031098,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031347,GO:0031349,GO:0031399,GO:0031401,GO:0031410,GO:0031663,GO:0031982,GO:0032088,GO:0032147,GO:0032268,GO:0032270,GO:0032368,GO:0032369,GO:0032371,GO:0032372,GO:0032374,GO:0032375,GO:0032479,GO:0032481,GO:0032494,GO:0032496,GO:0032501,GO:0032502,GO:0032872,GO:0032874,GO:0032879,GO:0032991,GO:0033554,GO:0033674,GO:0033993,GO:0034097,GO:0034134,GO:0034142,GO:0034162,GO:0034340,GO:0034605,GO:0035172,GO:0035556,GO:0035872,GO:0036211,GO:0038061,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042802,GO:0042803,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043122,GO:0043123,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043235,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043433,GO:0043506,GO:0043507,GO:0043549,GO:0043933,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045323,GO:0045859,GO:0045860,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045937,GO:0046328,GO:0046330,GO:0046777,GO:0046982,GO:0046983,GO:0048262,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048569,GO:0048583,GO:0048584,GO:0048660,GO:0048661,GO:0048731,GO:0048856,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050832,GO:0050896,GO:0051049,GO:0051051,GO:0051090,GO:0051091,GO:0051092,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0051338,GO:0051347,GO:0051403,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0060337,GO:0060548,GO:0060759,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070302,GO:0070304,GO:0070423,GO:0070498,GO:0070555,GO:0070851,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071345,GO:0071347,GO:0071357,GO:0071396,GO:0071704,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0090370,GO:0097708,GO:0098542,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098802,GO:0098805,GO:0140096,GO:1901222,GO:1901224,GO:1901564,GO:1901698,GO:1901700,GO:1901701,GO:1902531,GO:1902533,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1905952,GO:1905953,GO:2000112,GO:2000113,GO:2001141	2.7.11.1	ko:K04730	ko04010,ko04064,ko04620,ko04624,ko04722,ko05133,ko05140,ko05142,ko05145,ko05152,ko05162,ko05169,map04010,map04064,map04620,map04624,map04722,map05133,map05140,map05142,map05145,map05152,map05162,map05169	M00686	-	-	ko00000,ko00001,ko00002,ko01000,ko01001	-	-	-	Death,Pkinase,Pkinase_Tyr
k59_316620_1	1232410.KI421415_gene3124	7.75e-70	233.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43SDF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PAS domain	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_395587_1	246197.MXAN_5758	3.77e-59	196.0	COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,43203@68525|delta/epsilon subdivisions,2WWMI@28221|Deltaproteobacteria,2YTY1@29|Myxococcales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	cefD	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
k59_669456_1	991905.SL003B_4136	2.17e-109	325.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,2TTG7@28211|Alphaproteobacteria,4BT5R@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_3
k59_3563_1	935866.JAER01000040_gene495	3.07e-27	105.0	COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria,4DQK5@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	pecS	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_3563_2	1453501.JELR01000002_gene529	1.58e-27	111.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,466B9@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_473532_1	321846.PS417_02235	1.38e-30	117.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RPMN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	lipopolysaccharide heptosyltransferase I	rfaC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	iB21_1397.B21_03429,iECBD_1354.ECBD_0105,iECB_1328.ECB_03478,iECD_1391.ECD_03478,iECNA114_1301.ECNA114_3774,iECSF_1327.ECSF_3456,iSF_1195.SF3661,iS_1188.S4107	Glyco_transf_9
k59_473532_2	268407.PWYN_13270	7.83e-18	80.1	COG1683@1|root,COG1683@2|Bacteria,1V700@1239|Firmicutes,4HJH0@91061|Bacilli,26XN7@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF523)	ybbK	-	-	-	-	-	-	-	-	-	-	-	DUF523
k59_551954_1	314287.GB2207_10356	1.44e-21	95.1	COG2353@1|root,COG2353@2|Bacteria,1N3P9@1224|Proteobacteria,1SDBE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_3576_1	109478.XP_005871471.1	6.15e-173	488.0	COG1890@1|root,KOG1628@2759|Eukaryota,38EQE@33154|Opisthokonta,3BDUP@33208|Metazoa,3CS91@33213|Bilateria,48AD5@7711|Chordata,491B6@7742|Vertebrata,3J2XT@40674|Mammalia,4KQT6@9397|Chiroptera	33208|Metazoa	J	40S ribosomal protein	RPS3A	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008284,GO:0009058,GO:0009059,GO:0009636,GO:0009790,GO:0009792,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0010941,GO:0015935,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031369,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032991,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0042127,GO:0042221,GO:0042493,GO:0042981,GO:0043009,GO:0043043,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045471,GO:0045727,GO:0046677,GO:0048145,GO:0048146,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0060548,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097305,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904,GO:2000112	-	ko:K02984	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S3Ae
k59_1217842_1	1223523.H340_25087	7.68e-09	63.2	2DB7D@1|root,2Z7KR@2|Bacteria,2GKFW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_591237_1	34506.g1329	3.61e-23	97.8	COG0057@1|root,COG0126@1|root,KOG0657@2759|Eukaryota,KOG1367@2759|Eukaryota,38DPH@33154|Opisthokonta,3BA6Z@33208|Metazoa,3CRFX@33213|Bilateria,40FCJ@6231|Nematoda,1KUTI@119089|Chromadorea,40XK7@6236|Rhabditida	33208|Metazoa	G	Glyceraldehyde-3-phosphate dehydrogenase	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_591237_2	1384054.N790_04035	4.52e-104	309.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1X34S@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_985852_1	886377.Murru_3002	9.71e-41	144.0	COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,1HWW2@117743|Flavobacteriia	976|Bacteroidetes	H	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_515564_1	1280944.HY17_11840	0.000188	44.3	COG0251@1|root,COG0251@2|Bacteria,1PHJK@1224|Proteobacteria,2V89Y@28211|Alphaproteobacteria,4405J@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k59_515564_2	998674.ATTE01000001_gene3437	3.82e-44	146.0	COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,1S9GA@1236|Gammaproteobacteria,4631C@72273|Thiotrichales	72273|Thiotrichales	S	HIUase/Transthyretin family	-	-	-	-	-	-	-	-	-	-	-	-	Transthyretin
k59_515564_3	944435.AXAJ01000012_gene2995	3.53e-80	258.0	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2VI0J@28216|Betaproteobacteria,1K1BZ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Xanthine dehydrogenase small subunit	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
k59_241009_2	118163.Ple7327_3485	5.02e-63	196.0	COG0197@1|root,COG0197@2|Bacteria,1G55B@1117|Cyanobacteria,3VJMQ@52604|Pleurocapsales	1117|Cyanobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_515571_1	1121937.AUHJ01000023_gene198	2.01e-124	366.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,465NQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_1220688_1	1120970.AUBZ01000002_gene858	1.95e-09	58.2	COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria,1SC8X@1236|Gammaproteobacteria,468MJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	COG2165 Type II secretory pathway, pseudopilin PulG	gspI	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
k59_1220688_2	1323663.AROI01000016_gene419	5.43e-05	46.2	COG4795@1|root,COG4795@2|Bacteria	2|Bacteria	U	General secretion pathway protein	gspJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
k59_280181_1	1454004.AW11_03987	4.15e-36	125.0	2E9HQ@1|root,333QT@2|Bacteria,1N8T3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_280181_2	338969.Rfer_2015	2.46e-07	50.4	2E80B@1|root,332EM@2|Bacteria,1N7PZ@1224|Proteobacteria,2VVZX@28216|Betaproteobacteria,4AG3W@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_201685_1	313612.L8106_19913	2.88e-61	208.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1G16R@1117|Cyanobacteria,1H85V@1150|Oscillatoriales	1117|Cyanobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_907014_1	1117647.M5M_11490	4.84e-39	152.0	2BX7Z@1|root,2ZBYH@2|Bacteria,1RFFM@1224|Proteobacteria,1S5CF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	F plasmid transfer operon, TraF, protein	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
k59_710969_1	519989.ECTPHS_13138	4.35e-23	91.7	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,1WZ44@135613|Chromatiales	135613|Chromatiales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
k59_710969_2	983545.Glaag_3404	9.11e-57	181.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,466EY@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_907039_1	1121468.AUBR01000049_gene1632	4.23e-57	198.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1UT78@1239|Firmicutes,24A6H@186801|Clostridia,42FPJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_9,FlpD,Pyr_redox_2
k59_710989_1	401053.AciPR4_3007	4.57e-07	51.2	COG0482@1|root,COG0482@2|Bacteria,3Y2JX@57723|Acidobacteria,2JHKV@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_710989_2	56780.SYN_00797	3.33e-63	209.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,2MQCJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	MiaB-like tRNA modifying enzyme	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
k59_1103213_1	196367.JNFG01000002_gene2265	7.91e-78	246.0	COG1960@1|root,COG1960@2|Bacteria,1P7WH@1224|Proteobacteria,2VMPJ@28216|Betaproteobacteria,1K4I6@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
k59_45004_1	30611.ENSOGAP00000015602	3.63e-24	104.0	KOG1003@1|root,KOG1003@2759|Eukaryota,39YF6@33154|Opisthokonta,3BEAG@33208|Metazoa,3D3CN@33213|Bilateria,486BE@7711|Chordata,496ET@7742|Vertebrata,3J7SA@40674|Mammalia,35HRJ@314146|Euarchontoglires,4MIBW@9443|Primates	33208|Metazoa	Z	Belongs to the tropomyosin family	TPM3	-	-	ko:K09290	ko04260,ko04261,ko05200,ko05216,ko05410,ko05414,map04260,map04261,map05200,map05216,map05410,map05414	-	-	-	ko00000,ko00001,ko04812	-	-	-	Tropomyosin
k59_85003_1	511062.GU3_03905	1.45e-64	210.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1Y49M@135624|Aeromonadales	135624|Aeromonadales	C	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_710996_1	1242864.D187_004175	1.4e-22	102.0	COG2268@1|root,COG2268@2|Bacteria,1QIR4@1224|Proteobacteria,42Q0N@68525|delta/epsilon subdivisions,2WJDJ@28221|Deltaproteobacteria,2YX5U@29|Myxococcales	28221|Deltaproteobacteria	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
k59_398193_1	314285.KT71_000918	2.12e-147	423.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,1S1FB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3
k59_319311_1	1037409.BJ6T_06950	4.59e-21	97.8	COG1145@1|root,COG1148@1|root,COG1145@2|Bacteria,COG1148@2|Bacteria,1MWHY@1224|Proteobacteria,2TS71@28211|Alphaproteobacteria,3JSPD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_85018_1	1121405.dsmv_2233	7.87e-33	126.0	2ADFT@1|root,3135W@2|Bacteria,1MY8W@1224|Proteobacteria,42SW3@68525|delta/epsilon subdivisions,2WPYE@28221|Deltaproteobacteria,2MK86@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_633184_2	439235.Dalk_1357	3.61e-23	92.4	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria,2MK4F@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
k59_789706_1	247633.GP2143_10622	3.1e-69	229.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNYW@1236|Gammaproteobacteria,1J4TN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	OU	COG0616 Periplasmic serine proteases (ClpP class)	sppA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_280273_1	439235.Dalk_5062	8.32e-91	275.0	COG1035@1|root,COG4656@1|root,COG1035@2|Bacteria,COG4656@2|Bacteria,1NQN7@1224|Proteobacteria,42MGI@68525|delta/epsilon subdivisions,2WKNC@28221|Deltaproteobacteria,2MIJN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	hdrD	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_17,Fer4_8,FlpD,FrhB_FdhB_C
k59_711028_1	398767.Glov_2485	9.11e-66	213.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2WJRU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2495	GATase,Glycos_trans_3N,Glycos_transf_3
k59_1181842_1	1397528.Q671_14960	1.83e-38	144.0	COG3677@1|root,COG3677@2|Bacteria,1NUTK@1224|Proteobacteria,1S11R@1236|Gammaproteobacteria,1XS39@135619|Oceanospirillales	135619|Oceanospirillales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_359029_1	439235.Dalk_1817	1.87e-38	145.0	28XMP@1|root,2ZJIQ@2|Bacteria,1RCM0@1224|Proteobacteria,42R7U@68525|delta/epsilon subdivisions,2WN4H@28221|Deltaproteobacteria,2MKZX@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_672130_1	1042377.AFPJ01000016_gene119	5.47e-63	216.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464AK@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_711042_1	765912.Thimo_0237	3.76e-116	349.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1WWTF@135613|Chromatiales	135613|Chromatiales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
k59_985984_1	1232437.KL661978_gene3851	1.02e-112	343.0	COG2414@1|root,COG2414@2|Bacteria,1R76Y@1224|Proteobacteria,42QE3@68525|delta/epsilon subdivisions,2WIIW@28221|Deltaproteobacteria,2MIUU@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_1103272_1	268746.Q58MN4_BPPRM	1.58e-12	68.6	4QDYQ@10239|Viruses,4QVVQ@35237|dsDNA viruses  no RNA stage,4QPVQ@28883|Caudovirales,4QKJF@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1181857_1	317936.Nos7107_2309	2.43e-10	64.3	COG1566@1|root,COG1566@2|Bacteria,1G19K@1117|Cyanobacteria,1HPKG@1161|Nostocales	1117|Cyanobacteria	V	PFAM HlyD family secretion protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1063985_1	876044.IMCC3088_2027	1.32e-85	268.0	COG0477@1|root,COG2814@2|Bacteria,1MWKH@1224|Proteobacteria,1RNW6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	yjhB	GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_61927_1	479432.Sros_6604	1.12e-58	198.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.39	ko:K00146,ko:K11947	ko00360,ko00624,ko00643,ko01100,ko01120,ko01220,map00360,map00624,map00643,map01100,map01120,map01220	-	R02536,R05649	RC00075,RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_1044694_1	75379.Tint_0129	1.88e-117	359.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria,1KKYF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	von Willebrand factor (vWF) type A domain	cbbO	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
k59_649893_1	412965.COSY_0573	1.13e-45	163.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1J4IS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
k59_221859_1	909663.KI867150_gene2034	1.98e-86	264.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2MQFE@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1159772_1	156889.Mmc1_0349	9.33e-40	137.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VF2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
k59_1159772_2	436229.JOEH01000020_gene7784	6.89e-05	46.2	COG0476@1|root,COG0476@2|Bacteria,2HGW4@201174|Actinobacteria,2NKAQ@228398|Streptacidiphilus	201174|Actinobacteria	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_61953_1	864702.OsccyDRAFT_1392	1.55e-64	217.0	COG1834@1|root,COG1915@1|root,COG1834@2|Bacteria,COG1915@2|Bacteria,1G2AU@1117|Cyanobacteria,1H7S0@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf,Saccharop_dh_N
k59_535335_2	1122614.JHZF01000014_gene2594	1.17e-13	74.3	2DT0V@1|root,33I77@2|Bacteria,1NK6B@1224|Proteobacteria,2UM7W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1120770_1	666685.R2APBS1_3673	1.17e-33	130.0	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,1SGXK@1236|Gammaproteobacteria,1X6ZE@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_806043_1	1232437.KL662043_gene2231	2.97e-21	89.7	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,42V96@68525|delta/epsilon subdivisions,2WRGH@28221|Deltaproteobacteria,2MNZE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
k59_298543_1	10181.XP_004871987.1	1.53e-17	85.9	COG0293@1|root,KOG1099@2759|Eukaryota,38BSV@33154|Opisthokonta,3B9AJ@33208|Metazoa,3CTXU@33213|Bilateria,485TD@7711|Chordata,48Y2M@7742|Vertebrata,3J7RD@40674|Mammalia,35DHR@314146|Euarchontoglires,4Q2R0@9989|Rodentia	33208|Metazoa	D	FtsJ-like methyltransferase	FTSJ1	GO:0001510,GO:0002181,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016427,GO:0016740,GO:0016741,GO:0019538,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052666,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.1.166,2.1.1.205	ko:K02427,ko:K14864	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	FtsJ
k59_1242272_1	1030157.AFMP01000011_gene3695	6.81e-23	95.1	COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,2UCHN@28211|Alphaproteobacteria,2K5C8@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
k59_103041_1	1235803.C825_01882	7.25e-57	192.0	COG5434@1|root,COG5434@2|Bacteria,4NIEA@976|Bacteroidetes,2FMVC@200643|Bacteroidia	976|Bacteroidetes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
k59_23154_1	335543.Sfum_2498	1.56e-13	73.2	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42PIT@68525|delta/epsilon subdivisions,2WKT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_23154_2	1121918.ARWE01000001_gene1120	6.67e-80	245.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42PYJ@68525|delta/epsilon subdivisions,2WKHY@28221|Deltaproteobacteria,43SDA@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_337130_1	1167006.UWK_01346	3.5e-87	271.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42MBP@68525|delta/epsilon subdivisions,2WJAJ@28221|Deltaproteobacteria,2MHTN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_454408_2	467661.RKLH11_2796	1.18e-15	74.7	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,3ZHI7@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
k59_806064_1	1121396.KB892990_gene4485	1.18e-18	83.6	COG4974@1|root,COG4974@2|Bacteria,1NCBK@1224|Proteobacteria,42VT5@68525|delta/epsilon subdivisions,2WSFT@28221|Deltaproteobacteria,2MNYY@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_806064_2	1280688.AUJB01000011_gene2168	1.39e-14	80.5	COG0582@1|root,COG0582@2|Bacteria,1UZQ6@1239|Firmicutes,24D3E@186801|Clostridia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1080736_1	1415778.JQMM01000001_gene127	4.47e-34	132.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1J5RD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	enzyme of heme biosynthesis	hemY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_2
k59_689931_1	706587.Desti_1915	9.57e-55	190.0	COG1148@1|root,COG1149@1|root,COG1148@2|Bacteria,COG1149@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_689931_2	706587.Desti_1915	1.86e-32	125.0	COG1148@1|root,COG1149@1|root,COG1148@2|Bacteria,COG1149@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_1047284_1	243164.DET1309	1.25e-75	241.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi,34CVS@301297|Dehalococcoidia	301297|Dehalococcoidia	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
k59_731902_1	309801.trd_0418	3.5e-40	149.0	COG0297@1|root,COG0297@2|Bacteria,2GA6I@200795|Chloroflexi,27XJX@189775|Thermomicrobia	189775|Thermomicrobia	G	Glycosyl transferase 4-like domain	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_497076_2	118005.AWNK01000013_gene890	4.27e-27	112.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_301782_1	765912.Thimo_2864	2.27e-67	207.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,1WWE7@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_183052_1	349161.Dred_1346	2.13e-21	95.9	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4
k59_888932_1	9597.XP_008950096.1	8.82e-144	432.0	COG5165@1|root,KOG0526@2759|Eukaryota,38CT0@33154|Opisthokonta,3B9AQ@33208|Metazoa,3CXEP@33213|Bilateria,488PX@7711|Chordata,494IE@7742|Vertebrata,3JF47@40674|Mammalia,35JJG@314146|Euarchontoglires,4MIZR@9443|Primates,4MV0I@9604|Hominidae	33208|Metazoa	B	POB3-like N-terminal PH domain	SSRP1	GO:0000003,GO:0000981,GO:0001672,GO:0001932,GO:0001933,GO:0002064,GO:0002065,GO:0002066,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006725,GO:0006807,GO:0007276,GO:0007281,GO:0007292,GO:0008023,GO:0008064,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009888,GO:0009889,GO:0009892,GO:0009966,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010563,GO:0010605,GO:0010638,GO:0010646,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0030154,GO:0030707,GO:0030832,GO:0030833,GO:0030838,GO:0030855,GO:0031323,GO:0031324,GO:0031326,GO:0031334,GO:0031399,GO:0031400,GO:0031490,GO:0031491,GO:0031492,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032271,GO:0032273,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032774,GO:0032956,GO:0032970,GO:0032991,GO:0033043,GO:0033044,GO:0034641,GO:0034645,GO:0034654,GO:0035101,GO:0042325,GO:0042326,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043621,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044703,GO:0044877,GO:0045936,GO:0046483,GO:0048468,GO:0048477,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051098,GO:0051101,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051252,GO:0051493,GO:0051495,GO:0051704,GO:0060255,GO:0060429,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0090066,GO:0090304,GO:0097159,GO:0097659,GO:0110053,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901796,GO:1902275,GO:1902531,GO:1902903,GO:1902905,GO:1903506,GO:2000112,GO:2001141	-	ko:K09272	-	-	-	-	ko00000,ko03000	-	-	-	HMG_box,POB3_N,Rtt106,SSrecog
k59_1163104_1	518766.Rmar_0902	1.96e-74	248.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1FJ61@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_143745_1	1121405.dsmv_0369	1.42e-98	300.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2MHKJ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_693129_1	1384054.N790_13085	2.32e-74	237.0	COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1X4GC@135614|Xanthomonadales	135614|Xanthomonadales	E	Cystathionine beta-synthase	cysB	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
k59_693145_1	768671.ThimaDRAFT_3833	1.25e-93	277.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1WW9M@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_107142_1	314278.NB231_10088	9.63e-53	177.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1WW0I@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_107142_2	686578.AFFX01000005_gene4014	4.2e-35	123.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k59_1163158_1	1121405.dsmv_1968	2.16e-71	219.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,42U8S@68525|delta/epsilon subdivisions,2WQ8V@28221|Deltaproteobacteria,2MKT7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE-1	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k59_1202731_1	1502724.FF80_03057	1.25e-62	200.0	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,2TRKQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	aspartate racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
k59_967764_1	661367.LLO_0181	4.46e-30	124.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1JCGE@118969|Legionellales	118969|Legionellales	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1011834_1	426117.M446_5281	6.4e-60	191.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2TRCF@28211|Alphaproteobacteria,1JTSG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	IQ	TIGRFAM acetoacetyl-CoA reductase	-	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
k59_889003_1	177439.DP0767	4.05e-44	161.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,2MJA8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_380720_1	1168065.DOK_07654	4.35e-30	110.0	COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,1S61S@1236|Gammaproteobacteria,1J6FH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulators	liuR	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
k59_340575_1	1205680.CAKO01000040_gene851	1.3e-50	175.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2TTD2@28211|Alphaproteobacteria,2JYWZ@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
k59_262682_1	1195246.AGRI_12401	5.32e-20	95.5	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,4651V@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_539810_1	1265505.ATUG01000002_gene1088	9.78e-55	180.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2MJG9@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_771200_1	519989.ECTPHS_08116	2.18e-48	170.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria,1WWBR@135613|Chromatiales	135613|Chromatiales	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
k59_809156_1	335543.Sfum_0531	3.71e-12	66.2	COG1208@1|root,COG1208@2|Bacteria,1PDPD@1224|Proteobacteria,43A25@68525|delta/epsilon subdivisions,2X1ZV@28221|Deltaproteobacteria,2MRR3@213462|Syntrophobacterales	28221|Deltaproteobacteria	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
k59_693209_1	670307.HYPDE_36028	4.54e-124	356.0	COG0745@1|root,COG0745@2|Bacteria,1MWVI@1224|Proteobacteria,2TRSP@28211|Alphaproteobacteria,3N69F@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	two component transcriptional regulator	ctrA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K02483,ko:K13584	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_849676_1	1131269.AQVV01000001_gene1450	1.6e-45	158.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	mhpC	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
k59_497241_1	438753.AZC_1193	4.17e-57	192.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,3EYT1@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP,Thr_dehydrat_C
k59_1202817_1	1313172.YM304_34380	1.42e-90	273.0	COG0266@1|root,COG0266@2|Bacteria,2GKCW@201174|Actinobacteria	201174|Actinobacteria	L	Glycosylase	nei	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k59_1084095_1	987059.RBXJA2T_09859	4.86e-95	291.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYF@28216|Betaproteobacteria,1KK87@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_1084095_2	414684.RC1_3119	1.15e-45	163.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2JP9C@204441|Rhodospirillales	204441|Rhodospirillales	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_732088_1	1121405.dsmv_0133	2.75e-63	209.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42U4X@68525|delta/epsilon subdivisions,2WPU1@28221|Deltaproteobacteria,2MNE3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_4
k59_1202828_1	1144672.F966_00451	1.65e-65	215.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria,3NKKZ@468|Moraxellaceae	1236|Gammaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_65420_1	272134.KB731324_gene1880	1.15e-76	232.0	COG3153@1|root,COG3153@2|Bacteria,1G6H9@1117|Cyanobacteria,1HBUU@1150|Oscillatoriales	1117|Cyanobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
k59_1202840_2	933262.AXAM01000031_gene3022	1.17e-57	191.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2MI5I@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_539912_1	1232437.KL662016_gene1174	6.74e-65	205.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,43AA7@68525|delta/epsilon subdivisions,2X2GR@28221|Deltaproteobacteria,2MPBD@213118|Desulfobacterales	28221|Deltaproteobacteria	L	MULE transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_809215_1	338966.Ppro_3708	1.78e-63	204.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_340683_1	287.DR97_3866	1.36e-41	149.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1YD2Q@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Transglycosylase SLT domain	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_107324_1	666684.AfiDRAFT_0478	7.85e-90	294.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,3JSNT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_301998_1	243365.CV_3825	2.13e-39	139.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,2KR8V@206351|Neisseriales	206351|Neisseriales	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
k59_615305_3	1589733.A0A0C5AE10_9CAUD	4.82e-19	82.0	4QDSY@10239|Viruses,4QQ21@28883|Caudovirales,4QIPU@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_967909_1	640081.Dsui_2110	2.16e-59	194.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2VP05@28216|Betaproteobacteria	28216|Betaproteobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_65475_1	243233.MCA1740	4.4e-113	336.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,1XDU5@135618|Methylococcales	135618|Methylococcales	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	-	-	6.2.1.9	ko:K14067	ko00630,ko00680,ko01120,ko01200,map00630,map00680,map01120,map01200	M00346	R01256	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_65475_2	1283300.ATXB01000001_gene1604	4.71e-11	62.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1SKVW@1236|Gammaproteobacteria,1XDNK@135618|Methylococcales	135618|Methylococcales	H	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	-	-	6.2.1.9	ko:K08692	ko00630,ko00680,ko01120,ko01200,map00630,map00680,map01120,map01200	M00346	R01256	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
k59_732143_1	595460.RRSWK_00416	2.1e-53	176.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_732143_2	266834.SMc01712	6.33e-10	58.9	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,4BAWK@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases	lldD1	GO:0002218,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006950,GO:0006952,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010204,GO:0016999,GO:0017000,GO:0017144,GO:0023052,GO:0031347,GO:0031349,GO:0042579,GO:0042742,GO:0042743,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0050665,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0072593,GO:0080134,GO:0098542,GO:1903409	1.1.2.3	ko:K00101	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
k59_1245808_1	9606.ENSP00000407375	2.82e-18	80.9	COG0386@1|root,KOG1651@2759|Eukaryota,39SDJ@33154|Opisthokonta,3BMPB@33208|Metazoa,3CWHJ@33213|Bilateria,4853G@7711|Chordata,48VV9@7742|Vertebrata,3JBXN@40674|Mammalia,35E0J@314146|Euarchontoglires,4MIC3@9443|Primates,4N5CD@9604|Hominidae	33208|Metazoa	O	glutathione peroxidase activity	GPX1	GO:0000302,GO:0001101,GO:0001525,GO:0001568,GO:0001659,GO:0001667,GO:0001678,GO:0001885,GO:0001944,GO:0002064,GO:0002682,GO:0002683,GO:0002861,GO:0002862,GO:0003008,GO:0003013,GO:0003015,GO:0003018,GO:0003158,GO:0003674,GO:0003824,GO:0004601,GO:0004602,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006195,GO:0006464,GO:0006518,GO:0006575,GO:0006629,GO:0006631,GO:0006638,GO:0006639,GO:0006641,GO:0006690,GO:0006725,GO:0006749,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006928,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0007275,GO:0007517,GO:0007519,GO:0007568,GO:0007584,GO:0007600,GO:0007605,GO:0008015,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008631,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009314,GO:0009410,GO:0009411,GO:0009416,GO:0009605,GO:0009607,GO:0009608,GO:0009609,GO:0009611,GO:0009617,GO:0009628,GO:0009636,GO:0009650,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009888,GO:0009892,GO:0009894,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010212,GO:0010243,GO:0010269,GO:0010332,GO:0010466,GO:0010468,GO:0010605,GO:0010631,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0010951,GO:0012501,GO:0014070,GO:0014706,GO:0014902,GO:0014904,GO:0016209,GO:0016477,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017124,GO:0017144,GO:0018130,GO:0018158,GO:0019222,GO:0019372,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019725,GO:0019752,GO:0019904,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030154,GO:0030162,GO:0030855,GO:0031099,GO:0031323,GO:0031324,GO:0031329,GO:0031347,GO:0031348,GO:0031667,GO:0031974,GO:0032101,GO:0032102,GO:0032268,GO:0032269,GO:0032355,GO:0032501,GO:0032502,GO:0032787,GO:0033043,GO:0033194,GO:0033273,GO:0033500,GO:0033554,GO:0033599,GO:0033993,GO:0034284,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0035094,GO:0035150,GO:0035239,GO:0035295,GO:0035296,GO:0035556,GO:0036211,GO:0036473,GO:0040007,GO:0040011,GO:0040029,GO:0042060,GO:0042127,GO:0042176,GO:0042221,GO:0042246,GO:0042311,GO:0042493,GO:0042542,GO:0042592,GO:0042593,GO:0042692,GO:0042737,GO:0042743,GO:0042744,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043154,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043281,GO:0043403,GO:0043412,GO:0043436,GO:0043523,GO:0043534,GO:0043542,GO:0043603,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045444,GO:0045446,GO:0045454,GO:0045861,GO:0046434,GO:0046483,GO:0046486,GO:0046677,GO:0046700,GO:0048468,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048646,GO:0048731,GO:0048741,GO:0048747,GO:0048856,GO:0048869,GO:0048870,GO:0048871,GO:0048878,GO:0050678,GO:0050727,GO:0050728,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050877,GO:0050880,GO:0050896,GO:0050954,GO:0051128,GO:0051129,GO:0051130,GO:0051146,GO:0051171,GO:0051172,GO:0051179,GO:0051186,GO:0051187,GO:0051239,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0051450,GO:0051593,GO:0051674,GO:0051702,GO:0051704,GO:0051707,GO:0051716,GO:0051896,GO:0051897,GO:0052547,GO:0052548,GO:0055001,GO:0055002,GO:0055082,GO:0055086,GO:0055114,GO:0060047,GO:0060055,GO:0060255,GO:0060429,GO:0060537,GO:0060538,GO:0060548,GO:0061061,GO:0061136,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070887,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071704,GO:0072358,GO:0072359,GO:0072521,GO:0072523,GO:0072593,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0090130,GO:0090132,GO:0090199,GO:0090201,GO:0097190,GO:0097193,GO:0097237,GO:0097746,GO:0097755,GO:0098754,GO:0098869,GO:1900407,GO:1900408,GO:1901214,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901568,GO:1901575,GO:1901576,GO:1901698,GO:1901700,GO:1901701,GO:1902041,GO:1902042,GO:1902175,GO:1902176,GO:1902531,GO:1902532,GO:1902533,GO:1902882,GO:1902883,GO:1902903,GO:1902905,GO:1903050,GO:1903201,GO:1903202,GO:1903362,GO:1990748,GO:2000026,GO:2000116,GO:2000117,GO:2001233,GO:2001234,GO:2001236,GO:2001237,GO:2001242,GO:2001243	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
k59_1245808_2	61853.ENSNLEP00000008322	7.26e-91	266.0	COG0386@1|root,KOG1651@2759|Eukaryota,39SDJ@33154|Opisthokonta,3BMPB@33208|Metazoa,3CWHJ@33213|Bilateria,4853G@7711|Chordata,48VV9@7742|Vertebrata,3JBXN@40674|Mammalia,35E0J@314146|Euarchontoglires,4MIC3@9443|Primates	33208|Metazoa	O	glutathione peroxidase activity	GPX1	GO:0000302,GO:0001101,GO:0001525,GO:0001568,GO:0001659,GO:0001667,GO:0001678,GO:0001885,GO:0001944,GO:0002064,GO:0002682,GO:0002683,GO:0002861,GO:0002862,GO:0003008,GO:0003013,GO:0003015,GO:0003018,GO:0003158,GO:0003674,GO:0003824,GO:0004601,GO:0004602,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006195,GO:0006464,GO:0006518,GO:0006575,GO:0006629,GO:0006631,GO:0006638,GO:0006639,GO:0006641,GO:0006690,GO:0006725,GO:0006749,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006928,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0007275,GO:0007517,GO:0007519,GO:0007568,GO:0007584,GO:0007600,GO:0007605,GO:0008015,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008631,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009314,GO:0009410,GO:0009411,GO:0009416,GO:0009605,GO:0009607,GO:0009608,GO:0009609,GO:0009611,GO:0009617,GO:0009628,GO:0009636,GO:0009650,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009888,GO:0009892,GO:0009894,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010212,GO:0010243,GO:0010269,GO:0010332,GO:0010466,GO:0010468,GO:0010605,GO:0010631,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0010951,GO:0012501,GO:0014070,GO:0014706,GO:0014902,GO:0014904,GO:0016209,GO:0016477,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017124,GO:0017144,GO:0018130,GO:0018158,GO:0019222,GO:0019372,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019725,GO:0019752,GO:0019904,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030154,GO:0030162,GO:0030855,GO:0031099,GO:0031323,GO:0031324,GO:0031329,GO:0031347,GO:0031348,GO:0031667,GO:0031974,GO:0032101,GO:0032102,GO:0032268,GO:0032269,GO:0032355,GO:0032501,GO:0032502,GO:0032787,GO:0033043,GO:0033194,GO:0033273,GO:0033500,GO:0033554,GO:0033599,GO:0033993,GO:0034284,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0035094,GO:0035150,GO:0035239,GO:0035295,GO:0035296,GO:0035556,GO:0036211,GO:0036473,GO:0040007,GO:0040011,GO:0040029,GO:0042060,GO:0042127,GO:0042176,GO:0042221,GO:0042246,GO:0042311,GO:0042493,GO:0042542,GO:0042592,GO:0042593,GO:0042692,GO:0042737,GO:0042743,GO:0042744,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043154,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043281,GO:0043403,GO:0043412,GO:0043436,GO:0043523,GO:0043534,GO:0043542,GO:0043603,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045444,GO:0045446,GO:0045454,GO:0045861,GO:0046434,GO:0046483,GO:0046486,GO:0046677,GO:0046700,GO:0048468,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048646,GO:0048731,GO:0048741,GO:0048747,GO:0048856,GO:0048869,GO:0048870,GO:0048871,GO:0048878,GO:0050678,GO:0050727,GO:0050728,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050877,GO:0050880,GO:0050896,GO:0050954,GO:0051128,GO:0051129,GO:0051130,GO:0051146,GO:0051171,GO:0051172,GO:0051179,GO:0051186,GO:0051187,GO:0051239,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0051450,GO:0051593,GO:0051674,GO:0051702,GO:0051704,GO:0051707,GO:0051716,GO:0051896,GO:0051897,GO:0052547,GO:0052548,GO:0055001,GO:0055002,GO:0055082,GO:0055086,GO:0055114,GO:0060047,GO:0060055,GO:0060255,GO:0060429,GO:0060537,GO:0060538,GO:0060548,GO:0061061,GO:0061136,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070887,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071704,GO:0072358,GO:0072359,GO:0072521,GO:0072523,GO:0072593,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0090130,GO:0090132,GO:0090199,GO:0090201,GO:0097190,GO:0097193,GO:0097237,GO:0097746,GO:0097755,GO:0098754,GO:0098869,GO:1900407,GO:1900408,GO:1901214,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901568,GO:1901575,GO:1901576,GO:1901698,GO:1901700,GO:1901701,GO:1902041,GO:1902042,GO:1902175,GO:1902176,GO:1902531,GO:1902532,GO:1902533,GO:1902882,GO:1902883,GO:1902903,GO:1902905,GO:1903050,GO:1903201,GO:1903202,GO:1903362,GO:1990748,GO:2000026,GO:2000116,GO:2000117,GO:2001233,GO:2001234,GO:2001236,GO:2001237,GO:2001242,GO:2001243	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
k59_927057_1	1117647.M5M_01710	1.87e-34	130.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,1J4Y1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
k59_225571_1	1255043.TVNIR_3552	3.04e-71	228.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_128861_1	400668.Mmwyl1_0456	4.75e-13	65.9	COG1917@1|root,COG1917@2|Bacteria,1NAFB@1224|Proteobacteria,1SGQB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF861)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_3
k59_641430_1	1121403.AUCV01000013_gene3904	8.68e-87	263.0	COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,42MFY@68525|delta/epsilon subdivisions,2WJS5@28221|Deltaproteobacteria,2MJQ1@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k59_837420_1	589873.EP13_16920	8.07e-06	53.9	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,1S2RH@1236|Gammaproteobacteria,4676J@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
k59_1036321_1	1157708.KB907463_gene734	2.32e-95	288.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,4AB13@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein E	pilU	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_53501_1	404589.Anae109_2319	1.05e-24	103.0	COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,42X0D@68525|delta/epsilon subdivisions,2WT38@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
k59_132097_1	987059.RBXJA2T_18693	3.06e-88	268.0	COG0464@1|root,COG0464@2|Bacteria,1MUCN@1224|Proteobacteria,2VIA8@28216|Betaproteobacteria,1KJSZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	cbbX	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_876592_1	351160.RCIX1438	1.16e-05	52.4	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,2N9G1@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transferase
k59_1036328_1	485915.Dret_2491	2.06e-35	132.0	COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,42N9B@68525|delta/epsilon subdivisions,2WIYW@28221|Deltaproteobacteria,2M9VH@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
k59_996928_1	551275.KB899546_gene2023	6.82e-21	96.7	COG4773@1|root,COG4773@2|Bacteria,1R3UW@1224|Proteobacteria,2VFK2@28211|Alphaproteobacteria,43WU0@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_93940_1	94122.Shewana3_2749	1.91e-78	245.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,2Q9BN@267890|Shewanellaceae	1236|Gammaproteobacteria	V	PFAM ABC transporter related	ybhF	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_210640_1	930166.CD58_25465	2.19e-16	84.7	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	iECO103_1326.ECO103_1114	MVIN
k59_367789_1	1328313.DS2_03770	3.66e-06	52.4	2AEF4@1|root,314A4@2|Bacteria,1N9MZ@1224|Proteobacteria,1SWDK@1236|Gammaproteobacteria,46BXP@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_132122_1	243090.RB9498	9.26e-136	398.0	COG3119@1|root,COG3119@2|Bacteria,2IYIB@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_1190374_1	9541.XP_005586860.1	6.19e-122	364.0	COG0056@1|root,KOG1353@2759|Eukaryota,38ERH@33154|Opisthokonta,3BCEE@33208|Metazoa,3CU79@33213|Bilateria,489CP@7711|Chordata,497ZQ@7742|Vertebrata,3J34Z@40674|Mammalia,35DYV@314146|Euarchontoglires,4MJDD@9443|Primates,36AAX@314294|Cercopithecoidea	33208|Metazoa	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	ATP5A1	GO:0000166,GO:0000275,GO:0001936,GO:0001937,GO:0003674,GO:0003824,GO:0005102,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0005759,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006839,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0008144,GO:0008150,GO:0008152,GO:0008285,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0010594,GO:0010595,GO:0010632,GO:0010634,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016043,GO:0016310,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0019866,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030334,GO:0030335,GO:0030554,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040012,GO:0040017,GO:0042127,GO:0042287,GO:0042288,GO:0042407,GO:0042623,GO:0042625,GO:0042626,GO:0042776,GO:0043167,GO:0043168,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043492,GO:0043531,GO:0043532,GO:0043535,GO:0043536,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044769,GO:0045121,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0046907,GO:0046933,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050678,GO:0050680,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051270,GO:0051272,GO:0051641,GO:0051649,GO:0055085,GO:0055086,GO:0061024,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0097159,GO:0097367,GO:0098589,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098805,GO:0098857,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902600,GO:1990542,GO:2000145,GO:2000147	-	ko:K02132	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_915338_1	1121448.DGI_2243	4.12e-34	126.0	COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,42PNV@68525|delta/epsilon subdivisions,2WJVJ@28221|Deltaproteobacteria,2M8F6@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_915338_2	765420.OSCT_0700	5.5e-08	55.5	COG1022@1|root,COG1022@2|Bacteria,2G5S9@200795|Chloroflexi,37561@32061|Chloroflexia	32061|Chloroflexia	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_408510_1	1156937.MFUM_760001	2.57e-14	75.1	COG0579@1|root,COG0579@2|Bacteria,46X2Q@74201|Verrucomicrobia,37H5D@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_1231923_1	1096756.ATKN01000004_gene226	8.33e-47	161.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,1W7DZ@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
k59_328113_1	247639.MGP2080_08489	8.46e-45	159.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria	1224|Proteobacteria	V	Multidrug efflux pump	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_367839_1	706587.Desti_4447	6.13e-70	229.0	COG4191@1|root,COG4191@2|Bacteria,1R7KQ@1224|Proteobacteria,42PAP@68525|delta/epsilon subdivisions,2WITB@28221|Deltaproteobacteria,2MQZE@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Cache domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
k59_1150942_1	396588.Tgr7_1177	3.15e-76	237.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1WX6T@135613|Chromatiales	135613|Chromatiales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_563357_2	292415.Tbd_2648	1.01e-45	148.0	COG4576@1|root,COG4576@2|Bacteria,1MZNS@1224|Proteobacteria,2VUR7@28216|Betaproteobacteria,1KTCW@119069|Hydrogenophilales	119069|Hydrogenophilales	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
k59_563357_3	335283.Neut_0809	5.02e-24	92.4	COG4576@1|root,COG4576@2|Bacteria,1N7B1@1224|Proteobacteria,2VX39@28216|Betaproteobacteria	28216|Betaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
k59_1190421_1	335543.Sfum_1154	4.21e-38	134.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1MVQY@1224|Proteobacteria,42REC@68525|delta/epsilon subdivisions,2WNN1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
k59_955197_1	1232437.KL662020_gene721	1.66e-60	206.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WKBS@28221|Deltaproteobacteria,2MIDZ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
k59_602927_1	1079998.H8ZMR6_9CAUD	1.36e-43	159.0	4QB40@10239|Viruses,4QV3M@35237|dsDNA viruses  no RNA stage	10239|Viruses	S	DNA polymerase family B	-	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004527,GO:0004540,GO:0005575,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018130,GO:0018995,GO:0019058,GO:0019079,GO:0019438,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039686,GO:0039693,GO:0042025,GO:0042221,GO:0043170,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0050896,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902074	-	-	-	-	-	-	-	-	-	-	-
k59_876698_1	439235.Dalk_1463	3.78e-27	107.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1RJT0@1224|Proteobacteria,43CRQ@68525|delta/epsilon subdivisions,2X7ZB@28221|Deltaproteobacteria,2MPB2@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_14677_1	472759.Nhal_0521	5.52e-40	152.0	COG2203@1|root,COG3829@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9
k59_132219_2	596151.DesfrDRAFT_3061	8.01e-37	130.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42VTR@68525|delta/epsilon subdivisions,2X5PP@28221|Deltaproteobacteria,2MGU1@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
k59_250164_1	644282.Deba_1222	1.12e-119	349.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_1112018_2	555088.DealDRAFT_2662	3.42e-10	54.7	2EG3W@1|root,339VW@2|Bacteria,1VMRY@1239|Firmicutes,24VA7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1036548_1	232346.JHQL01000001_gene2398	1.12e-48	156.0	COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,1S9CP@1236|Gammaproteobacteria,1XKM7@135619|Oceanospirillales	135619|Oceanospirillales	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
k59_1036548_2	1286106.MPL1_08474	1.25e-38	131.0	COG3093@1|root,COG3093@2|Bacteria,1N2BD@1224|Proteobacteria,1S8Z4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	plasmid maintenance system antidote protein	yddM	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
k59_1232087_1	1265505.ATUG01000002_gene1613	2.04e-99	313.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,1MU0N@1224|Proteobacteria,43CWU@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_837607_1	1380386.JIAW01000010_gene4192	1.42e-55	185.0	COG2141@1|root,COG2141@2|Bacteria,2ICP1@201174|Actinobacteria,23BM6@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_915473_1	261292.Nit79A3_1525	1.34e-26	110.0	COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,2VQCX@28216|Betaproteobacteria,372VR@32003|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_408690_1	1280950.HJO_08989	3.55e-09	57.4	COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2TRRV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG2513 PEP phosphonomutase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
k59_408690_2	749222.Nitsa_1117	8.36e-20	89.7	COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,42U32@68525|delta/epsilon subdivisions,2YPTI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG3786 conserved	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_1036580_1	316067.Geob_2174	2.28e-19	81.6	COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2WR9I@28221|Deltaproteobacteria,43VI5@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
k59_1036580_2	1192034.CAP_4019	2.29e-14	73.9	COG1466@1|root,COG1466@2|Bacteria,1RHE9@1224|Proteobacteria,42SNR@68525|delta/epsilon subdivisions,2WP96@28221|Deltaproteobacteria,2Z1UE@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
k59_210840_1	1121405.dsmv_0479	1.22e-101	308.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2MIHR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_720607_1	1167006.UWK_00830	4.27e-82	250.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,42PYZ@68525|delta/epsilon subdivisions,2WK4B@28221|Deltaproteobacteria,2MI57@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15599	ko02010,map02010	M00188,M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.3,3.A.1.17.6	-	-	BPD_transp_1
k59_759131_1	177437.HRM2_16030	3.06e-28	114.0	COG2770@1|root,COG2770@2|Bacteria,1REI3@1224|Proteobacteria,42T9M@68525|delta/epsilon subdivisions,2WPWU@28221|Deltaproteobacteria,2MKDT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,dCache_1
k59_210865_1	871968.DESME_09990	1.56e-10	61.2	COG3581@1|root,COG3581@2|Bacteria,1TPPP@1239|Firmicutes,249C8@186801|Clostridia,25ZYH@186807|Peptococcaceae	186801|Clostridia	I	PFAM CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2229
k59_210865_2	1121289.JHVL01000004_gene2158	1.58e-38	139.0	COG1924@1|root,COG1924@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,36EIE@31979|Clostridiaceae	186801|Clostridia	I	PFAM ATPase, BadF BadG BcrA BcrD type	hgdC1	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k59_524682_1	648757.Rvan_0877	1.43e-09	59.3	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2TQUB@28211|Alphaproteobacteria,3N7AB@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	permease YjgP YjgQ family protein	MA20_28210	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_997232_1	471852.Tcur_0848	0.000914	43.9	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4EG63@85012|Streptosporangiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE,TPR_12
k59_603077_1	933262.AXAM01000067_gene856	1.59e-104	315.0	COG2807@1|root,COG2807@2|Bacteria,1QW3Y@1224|Proteobacteria,42MUB@68525|delta/epsilon subdivisions,2WIX2@28221|Deltaproteobacteria,2MJ4V@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Major facilitator superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
k59_328281_1	756272.Plabr_2376	2.85e-45	154.0	COG1028@1|root,COG1028@2|Bacteria,2IZC3@203682|Planctomycetes	203682|Planctomycetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_603078_1	243231.GSU1257	5.22e-27	113.0	COG0683@1|root,COG2010@1|root,COG0683@2|Bacteria,COG2010@2|Bacteria,1R9N0@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Peripla_BP_6
k59_445925_1	1247963.JPHU01000005_gene264	1.03e-83	265.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	mmgC	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249,ko:K20035	ko00071,ko00280,ko00410,ko00640,ko00650,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map00920,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R11130	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246,RC03363	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_1151107_1	1479238.JQMZ01000001_gene199	1.92e-13	70.5	28PQS@1|root,2ZCCP@2|Bacteria,1NCXC@1224|Proteobacteria,2U2KV@28211|Alphaproteobacteria,43X0G@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1151107_2	388739.RSK20926_18102	1.02e-37	134.0	COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria,2TRRW@28211|Alphaproteobacteria,2P2PA@2433|Roseobacter	28211|Alphaproteobacteria	S	metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain	alaS2	GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
k59_94191_1	889378.Spiaf_0306	7.3e-39	148.0	COG1391@1|root,COG1391@2|Bacteria	2|Bacteria	H	[glutamate-ammonia-ligase] adenylyltransferase activity	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_368046_1	1207076.ALAT01000028_gene166	2.22e-190	543.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,1Z1N4@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_24,rve
k59_171606_1	1123487.KB892863_gene1917	3.17e-42	145.0	COG3063@1|root,COG3063@2|Bacteria,1RD9T@1224|Proteobacteria,2VQ2E@28216|Betaproteobacteria,2KWK0@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_408804_1	1122603.ATVI01000007_gene1481	1.52e-20	94.4	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,1X4VN@135614|Xanthomonadales	135614|Xanthomonadales	D	Reduces the stability of FtsZ polymers in the presence of ATP	zapE	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
k59_94207_1	1284352.AOIG01000008_gene2441	2.82e-10	65.9	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,26QIY@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	oppA1	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_759190_1	264462.Bd1158	2.12e-08	61.2	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2MSR8@213481|Bdellovibrionales,2WJZF@28221|Deltaproteobacteria	213481|Bdellovibrionales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_1036698_1	96561.Dole_2547	5.54e-31	125.0	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria,2MI3Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_289569_1	393595.ABO_0923	5.02e-98	303.0	2DBB7@1|root,2Z85R@2|Bacteria,1Q2HC@1224|Proteobacteria,1S22X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_94213_1	247634.GPB2148_3491	3.84e-80	250.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1J4I6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1232266_1	1254432.SCE1572_00935	9.49e-68	220.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,437V8@68525|delta/epsilon subdivisions,2X34Q@28221|Deltaproteobacteria,2YU9A@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	dapE1	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_798051_1	1197906.CAJQ02000010_gene3468	7.41e-12	61.6	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,3JYUA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Belongs to the P(II) protein family	glnB	GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_798051_2	1265505.ATUG01000001_gene3204	2.05e-85	265.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2WJE2@28221|Deltaproteobacteria,2MISS@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_368085_1	768671.ThimaDRAFT_0156	1.4e-11	65.9	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,1S5ET@1236|Gammaproteobacteria,1WYQP@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
k59_1232270_1	338966.Ppro_3708	3.71e-63	204.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_1232270_2	1380391.JIAS01000019_gene1155	1.02e-29	116.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,2JTER@204441|Rhodospirillales	204441|Rhodospirillales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_289602_1	290397.Adeh_0721	1.31e-79	261.0	COG0568@1|root,COG1196@1|root,COG0568@2|Bacteria,COG1196@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_1036785_1	1304275.C41B8_18030	2.93e-51	172.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
k59_368116_2	489825.LYNGBM3L_74400	2.6e-09	60.8	COG2199@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GPXH@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PHY,Response_reg
k59_1039623_2	1121405.dsmv_0363	1.25e-39	137.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42NR9@68525|delta/epsilon subdivisions,2WKX1@28221|Deltaproteobacteria,2MHZU@213118|Desulfobacterales	28221|Deltaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_330680_1	1207076.ALAT01000230_gene658	1.11e-91	288.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1Z179@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_213470_1	526222.Desal_2247	7.6e-14	66.6	COG1977@1|root,COG1977@2|Bacteria,1NH6M@1224|Proteobacteria,42X05@68525|delta/epsilon subdivisions,2WSK5@28221|Deltaproteobacteria,2MD55@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM ThiamineS	-	-	-	-	-	-	-	-	-	-	-	-	ThiS,Ub-Mut7C
k59_977935_1	1047013.AQSP01000142_gene126	1.8e-92	286.0	COG2070@1|root,COG2070@2|Bacteria,2NNYB@2323|unclassified Bacteria	2|Bacteria	S	Nitronate monooxygenase	npd	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
k59_898718_1	1232437.KL661957_gene2900	2.71e-09	55.8	COG0316@1|root,COG0316@2|Bacteria,1N8FK@1224|Proteobacteria,42VBF@68525|delta/epsilon subdivisions,2WR7Y@28221|Deltaproteobacteria,2MKZ6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the HesB IscA family	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
k59_350362_1	384765.SIAM614_29761	7.81e-50	174.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TT4X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_192087_1	631362.Thi970DRAFT_02714	9.83e-89	272.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1T20Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347,ko:K03614	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
k59_506675_1	1265505.ATUG01000002_gene1878	1.08e-87	272.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFQ@28221|Deltaproteobacteria,2MPSJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_74505_1	1177928.TH2_11774	3.85e-61	200.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2TT0T@28211|Alphaproteobacteria,2JRFT@204441|Rhodospirillales	204441|Rhodospirillales	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_624808_1	298654.FraEuI1c_5114	2.34e-68	222.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4EV93@85013|Frankiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_741641_1	519989.ECTPHS_06497	1.1e-51	171.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1WY4Z@135613|Chromatiales	135613|Chromatiales	NU	PFAM Fimbrial assembly	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
k59_467075_1	667014.Thein_1260	6.71e-68	224.0	COG1916@1|root,COG1916@2|Bacteria,2GGX4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_152978_2	351016.RAZWK3B_20676	1.48e-49	162.0	COG0346@1|root,COG0346@2|Bacteria,1RFNK@1224|Proteobacteria,2U807@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
k59_662362_1	1499967.BAYZ01000170_gene5496	1.68e-42	156.0	COG1032@1|root,COG1032@2|Bacteria	1499967.BAYZ01000170_gene5496|-	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_585274_1	1123393.KB891316_gene1686	7.02e-41	151.0	COG0617@1|root,COG1371@1|root,COG0617@2|Bacteria,COG1371@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,1KRHG@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Archease,HD,PolyA_pol,PolyA_pol_RNAbd
k59_192168_1	247633.GP2143_13191	6.06e-45	154.0	COG0561@1|root,COG0561@2|Bacteria,1MXIH@1224|Proteobacteria,1RQH8@1236|Gammaproteobacteria,1JBN8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	haloacid dehalogenase-like hydrolase	yidA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050308	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
k59_780955_1	335543.Sfum_2955	1.68e-66	218.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42NWT@68525|delta/epsilon subdivisions,2X5DA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1173206_2	880072.Desac_2069	1.65e-40	142.0	COG2122@1|root,COG2122@2|Bacteria,1MV9Z@1224|Proteobacteria,42PMZ@68525|delta/epsilon subdivisions,2WMF7@28221|Deltaproteobacteria,2MQFT@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM ApbE family	-	-	-	ko:K09740	-	-	-	-	ko00000	-	-	-	-
k59_506819_1	232721.Ajs_3074	1.26e-65	218.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria,4AB3C@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,Acyltransferase,PP-binding
k59_74633_1	1232410.KI421421_gene3541	2.17e-32	119.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,42WGY@68525|delta/epsilon subdivisions,2WS4W@28221|Deltaproteobacteria,43VDK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k59_117333_1	9606.ENSP00000225698	6.97e-106	310.0	KOG4024@1|root,KOG4024@2759|Eukaryota,39UTR@33154|Opisthokonta,3BB5X@33208|Metazoa,3CWEQ@33213|Bilateria,4885H@7711|Chordata,48ZJ5@7742|Vertebrata,3JBGE@40674|Mammalia,35EGQ@314146|Euarchontoglires,4M8ZI@9443|Primates,4N3CM@9604|Hominidae	33208|Metazoa	K	Complement component 1, q subcomponent binding protein	C1QBP	GO:0000003,GO:0000122,GO:0001664,GO:0001817,GO:0001818,GO:0001846,GO:0001848,GO:0001849,GO:0002376,GO:0002673,GO:0002682,GO:0002683,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0002697,GO:0002698,GO:0002831,GO:0002832,GO:0002920,GO:0003674,GO:0003676,GO:0003712,GO:0003714,GO:0003723,GO:0003729,GO:0005080,GO:0005102,GO:0005488,GO:0005515,GO:0005539,GO:0005540,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006338,GO:0006355,GO:0006357,GO:0006417,GO:0006807,GO:0006950,GO:0006955,GO:0006996,GO:0006997,GO:0007154,GO:0007165,GO:0007267,GO:0007268,GO:0007274,GO:0007338,GO:0007596,GO:0007597,GO:0007599,GO:0008134,GO:0008150,GO:0008152,GO:0009566,GO:0009611,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010720,GO:0010769,GO:0010770,GO:0010810,GO:0010811,GO:0010941,GO:0010942,GO:0014065,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022613,GO:0022618,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030155,GO:0030162,GO:0030334,GO:0030335,GO:0030449,GO:0030984,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031347,GO:0031348,GO:0031406,GO:0031497,GO:0031690,GO:0031974,GO:0032101,GO:0032102,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032649,GO:0032655,GO:0032689,GO:0032695,GO:0032879,GO:0032991,GO:0033119,GO:0034248,GO:0034250,GO:0034622,GO:0034728,GO:0035039,GO:0035041,GO:0035042,GO:0035556,GO:0036094,GO:0039531,GO:0039532,GO:0039533,GO:0039534,GO:0039535,GO:0039536,GO:0040012,GO:0040017,GO:0042060,GO:0042254,GO:0042255,GO:0042256,GO:0042393,GO:0042981,GO:0043021,GO:0043022,GO:0043044,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043484,GO:0043486,GO:0043900,GO:0043901,GO:0043902,GO:0043933,GO:0044085,GO:0044238,GO:0044421,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044877,GO:0045088,GO:0045595,GO:0045597,GO:0045727,GO:0045785,GO:0045892,GO:0045934,GO:0048015,GO:0048017,GO:0048024,GO:0048025,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050684,GO:0050686,GO:0050687,GO:0050688,GO:0050727,GO:0050776,GO:0050789,GO:0050793,GO:0050794,GO:0050817,GO:0050848,GO:0050878,GO:0050896,GO:0050920,GO:0050921,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051270,GO:0051272,GO:0051276,GO:0051704,GO:0051716,GO:0051896,GO:0051897,GO:0060255,GO:0060284,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0070013,GO:0070129,GO:0070131,GO:0070613,GO:0070925,GO:0071103,GO:0071622,GO:0071624,GO:0071704,GO:0071824,GO:0071826,GO:0071840,GO:0071944,GO:0072376,GO:0072378,GO:0080090,GO:0080134,GO:0090022,GO:0090023,GO:0097159,GO:0097177,GO:0097367,GO:0098916,GO:0099536,GO:0099537,GO:0140110,GO:1900024,GO:1900026,GO:1901163,GO:1901165,GO:1901363,GO:1901564,GO:1902531,GO:1902532,GO:1902533,GO:1902622,GO:1902624,GO:1902679,GO:1903311,GO:1903312,GO:1903317,GO:1903506,GO:1903507,GO:2000026,GO:2000112,GO:2000113,GO:2000145,GO:2000147,GO:2000241,GO:2000243,GO:2000257,GO:2000508,GO:2000510,GO:2001141	-	ko:K15414	ko05168,map05168	-	-	-	ko00000,ko00001,ko00536	-	-	-	MAM33
k59_350522_1	1121405.dsmv_1081	3.03e-40	147.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,42NBB@68525|delta/epsilon subdivisions,2WIMD@28221|Deltaproteobacteria,2MIEB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM ResB family protein	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
k59_1093560_1	582899.Hden_0630	9.3e-87	277.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2TRC1@28211|Alphaproteobacteria,3N6K7@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
k59_117342_1	522306.CAP2UW1_1755	8.97e-45	157.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2VHA2@28216|Betaproteobacteria	28216|Betaproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_858964_1	1265313.HRUBRA_00318	1.18e-54	186.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
k59_311202_1	1492922.GY26_06065	9.5e-19	86.3	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1J58N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_311202_2	1340493.JNIF01000003_gene1868	9.3e-10	62.8	COG0373@1|root,COG0373@2|Bacteria,3Y3DQ@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_1093588_1	472759.Nhal_3943	2.53e-82	261.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1WW41@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_662452_1	1267005.KB911258_gene555	4.83e-105	334.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,3N6ID@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_117353_1	1127673.GLIP_1686	3.99e-73	245.0	COG1629@1|root,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,1S13U@1236|Gammaproteobacteria,469BN@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_859005_1	1121921.KB898706_gene2634	5.13e-98	303.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,2PN9E@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	L	TopoisomeraseII	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_859012_3	1211115.ALIQ01000219_gene1427	3.58e-25	107.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TUKX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_192258_1	27679.XP_010342619.1	1.23e-126	374.0	COG0459@1|root,KOG0360@2759|Eukaryota,38BK8@33154|Opisthokonta,3BAMK@33208|Metazoa,3CUQM@33213|Bilateria,482KE@7711|Chordata,498J1@7742|Vertebrata,3JD9Y@40674|Mammalia,35E07@314146|Euarchontoglires,4MEK8@9443|Primates	33208|Metazoa	O	Assists the folding of proteins upon ATP hydrolysis	TCP1	GO:0000003,GO:0000228,GO:0000242,GO:0000785,GO:0000790,GO:0000792,GO:0001669,GO:0002199,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005720,GO:0005737,GO:0005794,GO:0005813,GO:0005815,GO:0005829,GO:0005832,GO:0005856,GO:0005874,GO:0006403,GO:0006457,GO:0006458,GO:0006810,GO:0007021,GO:0007154,GO:0007165,GO:0007166,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007338,GO:0007339,GO:0008037,GO:0008104,GO:0008150,GO:0009566,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009988,GO:0010033,GO:0010556,GO:0010557,GO:0010604,GO:0010638,GO:0010941,GO:0012505,GO:0015031,GO:0015630,GO:0015833,GO:0016043,GO:0019219,GO:0019221,GO:0019222,GO:0019899,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030141,GO:0030154,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031410,GO:0031625,GO:0031647,GO:0031974,GO:0031981,GO:0031982,GO:0032204,GO:0032206,GO:0032210,GO:0032212,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032880,GO:0032991,GO:0033032,GO:0033036,GO:0033043,GO:0033044,GO:0034097,GO:0034622,GO:0035036,GO:0035722,GO:0042000,GO:0042221,GO:0042886,GO:0042981,GO:0043067,GO:0043085,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044053,GO:0044085,GO:0044093,GO:0044183,GO:0044297,GO:0044389,GO:0044403,GO:0044417,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044445,GO:0044446,GO:0044450,GO:0044454,GO:0044464,GO:0044703,GO:0044766,GO:0045184,GO:0045935,GO:0048232,GO:0048468,GO:0048515,GO:0048518,GO:0048522,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050896,GO:0051052,GO:0051054,GO:0051082,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051338,GO:0051347,GO:0051701,GO:0051704,GO:0051716,GO:0051808,GO:0051836,GO:0051972,GO:0051973,GO:0060255,GO:0060341,GO:0061077,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070202,GO:0070203,GO:0070671,GO:0070887,GO:0071310,GO:0071345,GO:0071349,GO:0071702,GO:0071705,GO:0071840,GO:0080090,GO:0090666,GO:0090670,GO:0090685,GO:0097223,GO:0097708,GO:0099080,GO:0099081,GO:0099503,GO:0099512,GO:0099513,GO:0101031,GO:1901998,GO:1902579,GO:1903827,GO:1903829,GO:1904356,GO:1904358,GO:1904814,GO:1904816,GO:1904851,GO:1904872,GO:1904874,GO:1904951,GO:2000106,GO:2000109,GO:2000112,GO:2000278,GO:2000573,GO:2001252	-	ko:K09493	-	-	-	-	ko00000,ko03036,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_153145_1	1382359.JIAL01000001_gene417	1.12e-31	125.0	COG0037@1|root,COG0037@2|Bacteria,3Y2F2@57723|Acidobacteria,2JHX8@204432|Acidobacteriia	204432|Acidobacteriia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
k59_311252_1	269799.Gmet_1624	1.47e-62	205.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2WIP2@28221|Deltaproteobacteria,43T8J@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1624	RibD_C,dCMP_cyt_deam_1
k59_192295_1	1117647.M5M_15080	3.89e-105	319.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1J4NK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_36172_1	396588.Tgr7_2123	1.16e-90	284.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales	135613|Chromatiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_155995_1	436308.Nmar_0057	1.38e-89	266.0	COG2242@1|root,arCOG00977@2157|Archaea,41SID@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7	cbiT	-	2.1.1.196	ko:K02191	ko00860,map00860	-	R05813,R07774	RC00003,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	Methyltransf_31
k59_156000_1	1085623.GNIT_3009	5.17e-104	317.0	COG0312@1|root,COG0312@2|Bacteria,1NSH6@1224|Proteobacteria,1RR3H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Modulator of DNA gyrase	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_38943_1	933262.AXAM01000051_gene2982	8.9e-19	84.7	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MIVB@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
k59_194851_1	1232410.KI421424_gene1713	5.87e-68	221.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,42PD3@68525|delta/epsilon subdivisions,2WJ58@28221|Deltaproteobacteria,43SD6@69541|Desulfuromonadales	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
k59_194892_1	1211813.CAPH01000006_gene1546	8.18e-59	206.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2FNAJ@200643|Bacteroidia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bpeF	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_939857_1	30611.ENSOGAP00000019065	3.98e-25	95.5	KOG4794@1|root,KOG4794@2759|Eukaryota,3A8VT@33154|Opisthokonta,3BU3U@33208|Metazoa,3DAKV@33213|Bilateria,48GM6@7711|Chordata,49DH7@7742|Vertebrata,3JI5G@40674|Mammalia,35R6H@314146|Euarchontoglires,4MKAY@9443|Primates	33208|Metazoa	N	Thymosin beta actin-binding motif.	TMSB4X	GO:0001817,GO:0001818,GO:0002576,GO:0002682,GO:0002683,GO:0002684,GO:0002685,GO:0002686,GO:0002687,GO:0002688,GO:0002689,GO:0002791,GO:0002792,GO:0003674,GO:0003779,GO:0003785,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005856,GO:0006140,GO:0006355,GO:0006810,GO:0006887,GO:0007154,GO:0007165,GO:0007166,GO:0007253,GO:0008064,GO:0008092,GO:0008104,GO:0008150,GO:0009719,GO:0009725,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010155,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010594,GO:0010595,GO:0010604,GO:0010628,GO:0010632,GO:0010634,GO:0010639,GO:0010646,GO:0010648,GO:0012505,GO:0014070,GO:0014910,GO:0014911,GO:0016043,GO:0016192,GO:0019219,GO:0019220,GO:0019221,GO:0019222,GO:0019899,GO:0022898,GO:0023051,GO:0023052,GO:0023057,GO:0030141,GO:0030334,GO:0030335,GO:0030336,GO:0030808,GO:0030810,GO:0030832,GO:0030833,GO:0030837,GO:0031091,GO:0031093,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031333,GO:0031347,GO:0031348,GO:0031410,GO:0031960,GO:0031974,GO:0031982,GO:0031983,GO:0032088,GO:0032101,GO:0032102,GO:0032103,GO:0032271,GO:0032272,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032507,GO:0032535,GO:0032677,GO:0032717,GO:0032781,GO:0032870,GO:0032879,GO:0032880,GO:0032940,GO:0032956,GO:0032970,GO:0033036,GO:0033043,GO:0033209,GO:0033993,GO:0034097,GO:0034612,GO:0034613,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0034774,GO:0040012,GO:0040013,GO:0040017,GO:0042221,GO:0042989,GO:0042994,GO:0043085,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043269,GO:0043270,GO:0043392,GO:0043433,GO:0043462,GO:0043535,GO:0043536,GO:0044087,GO:0044092,GO:0044093,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045185,GO:0045595,GO:0045597,GO:0045893,GO:0045935,GO:0045937,GO:0045981,GO:0046903,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0050707,GO:0050708,GO:0050709,GO:0050710,GO:0050727,GO:0050728,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0050920,GO:0050921,GO:0050922,GO:0051046,GO:0051048,GO:0051049,GO:0051050,GO:0051051,GO:0051090,GO:0051094,GO:0051098,GO:0051100,GO:0051101,GO:0051128,GO:0051129,GO:0051147,GO:0051149,GO:0051150,GO:0051152,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051220,GO:0051223,GO:0051224,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051254,GO:0051270,GO:0051271,GO:0051272,GO:0051336,GO:0051345,GO:0051384,GO:0051493,GO:0051494,GO:0051641,GO:0051651,GO:0051716,GO:0060205,GO:0060255,GO:0061041,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070727,GO:0070887,GO:0071310,GO:0071345,GO:0071356,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071495,GO:0071622,GO:0071623,GO:0071840,GO:0080090,GO:0080134,GO:0090022,GO:0090024,GO:0090066,GO:0090087,GO:0090303,GO:0097708,GO:0099503,GO:0110053,GO:1900371,GO:1900373,GO:1900542,GO:1900544,GO:1901222,GO:1901223,GO:1902531,GO:1902532,GO:1902622,GO:1902623,GO:1902624,GO:1902680,GO:1902903,GO:1902904,GO:1903025,GO:1903026,GO:1903034,GO:1903036,GO:1903506,GO:1903508,GO:1903530,GO:1903531,GO:1903578,GO:1903580,GO:1904062,GO:1904064,GO:1904950,GO:1905271,GO:1905273,GO:2000112,GO:2000145,GO:2000146,GO:2000147,GO:2000482,GO:2000483,GO:2000677,GO:2000678,GO:2001026,GO:2001028,GO:2001141,GO:2001169,GO:2001171	-	ko:K05764	ko04810,map04810	-	-	-	ko00000,ko00001,ko04812	-	-	-	Thymosin
k59_156069_1	748658.KB907319_gene764	2.88e-73	229.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k59_1096789_1	1123261.AXDW01000001_gene1210	1.11e-72	236.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1S12C@1236|Gammaproteobacteria,1X9HS@135614|Xanthomonadales	135614|Xanthomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_194931_1	161528.ED21_23751	3.48e-10	61.6	COG1142@1|root,COG1142@2|Bacteria,1RIXA@1224|Proteobacteria,2UDYU@28211|Alphaproteobacteria,2K5SC@204457|Sphingomonadales	204457|Sphingomonadales	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1096795_1	335543.Sfum_3197	3.3e-125	375.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria,2MQ7P@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_156105_1	880072.Desac_1832	5.6e-44	158.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,2MQ88@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_39045_1	261292.Nit79A3_0779	5.39e-06	47.8	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,371SI@32003|Nitrosomonadales	28216|Betaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
k59_939924_1	880072.Desac_0827	1.13e-54	187.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43DC7@68525|delta/epsilon subdivisions,2X8I7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
k59_940026_1	1442599.JAAN01000030_gene2146	1e-93	293.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1X4Q2@135614|Xanthomonadales	135614|Xanthomonadales	S	transporter	oliA	-	-	-	-	-	-	-	-	-	-	-	OPT
k59_940027_1	1408428.JNJP01000007_gene1902	3.56e-09	57.8	COG5598@1|root,COG5598@2|Bacteria,1N18H@1224|Proteobacteria,43BDY@68525|delta/epsilon subdivisions,2X6SF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
k59_940027_2	1265505.ATUG01000001_gene4312	2.4e-40	138.0	COG5598@1|root,COG5598@2|Bacteria,1NY0Q@1224|Proteobacteria,430P1@68525|delta/epsilon subdivisions,2WVPQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
k59_665719_1	1265503.KB905163_gene2093	2.42e-42	149.0	COG1595@1|root,COG1595@2|Bacteria,1R7KF@1224|Proteobacteria,1S2IU@1236|Gammaproteobacteria,2Q6VY@267889|Colwelliaceae	1236|Gammaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_940068_1	102232.GLO73106DRAFT_00020370	1.93e-98	291.0	COG0426@1|root,COG0426@2|Bacteria	2|Bacteria	C	nitric oxide reductase activity	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Fer4,Lactamase_B
k59_940081_1	1416760.AYMS01000051_gene190	7.22e-28	113.0	COG3547@1|root,COG3547@2|Bacteria,4NIKY@976|Bacteroidetes,1HZCU@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_156280_1	1123253.AUBD01000004_gene1059	3.87e-30	110.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,1SCH5@1236|Gammaproteobacteria,1X7P3@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
k59_156280_2	396588.Tgr7_1108	3.65e-46	152.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1S73Y@1236|Gammaproteobacteria,1X24K@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_156280_3	1236501.BAJU01000007_gene1086	4.85e-08	53.9	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,2JPND@204441|Rhodospirillales	204441|Rhodospirillales	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_940105_1	60711.ENSCSAP00000007632	1.27e-230	647.0	COG0459@1|root,KOG0356@2759|Eukaryota,38BJH@33154|Opisthokonta,3BE0G@33208|Metazoa,3CX9K@33213|Bilateria,4804Y@7711|Chordata,49073@7742|Vertebrata,3JDS5@40674|Mammalia,35DDH@314146|Euarchontoglires,4MF6R@9443|Primates,35ZX5@314294|Cercopithecoidea	33208|Metazoa	O	Belongs to the chaperonin (HSP60) family	HSPD1	GO:0000302,GO:0001530,GO:0001666,GO:0001775,GO:0001816,GO:0001817,GO:0001819,GO:0002020,GO:0002039,GO:0002119,GO:0002164,GO:0002200,GO:0002204,GO:0002208,GO:0002218,GO:0002221,GO:0002224,GO:0002237,GO:0002250,GO:0002252,GO:0002253,GO:0002263,GO:0002285,GO:0002312,GO:0002366,GO:0002367,GO:0002368,GO:0002376,GO:0002377,GO:0002381,GO:0002440,GO:0002443,GO:0002449,GO:0002460,GO:0002520,GO:0002562,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0002697,GO:0002699,GO:0002703,GO:0002705,GO:0002706,GO:0002708,GO:0002709,GO:0002711,GO:0002755,GO:0002757,GO:0002758,GO:0002764,GO:0002791,GO:0002793,GO:0002819,GO:0002821,GO:0002822,GO:0002824,GO:0002831,GO:0002833,GO:0002834,GO:0002836,GO:0002837,GO:0002839,GO:0002840,GO:0002842,GO:0002931,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003697,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005768,GO:0005769,GO:0005777,GO:0005782,GO:0005783,GO:0005791,GO:0005794,GO:0005829,GO:0005886,GO:0005905,GO:0006139,GO:0006259,GO:0006310,GO:0006355,GO:0006357,GO:0006457,GO:0006458,GO:0006605,GO:0006626,GO:0006725,GO:0006807,GO:0006810,GO:0006839,GO:0006886,GO:0006915,GO:0006919,GO:0006950,GO:0006955,GO:0006979,GO:0006986,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007584,GO:0008035,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008289,GO:0008637,GO:0009266,GO:0009408,GO:0009409,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009719,GO:0009725,GO:0009790,GO:0009791,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009986,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010604,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0012505,GO:0014070,GO:0014074,GO:0014823,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016064,GO:0016444,GO:0016445,GO:0016447,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017038,GO:0017046,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0019724,GO:0019866,GO:0019899,GO:0022407,GO:0022409,GO:0022607,GO:0023052,GO:0030061,GO:0030135,GO:0030141,GO:0030155,GO:0030162,GO:0031090,GO:0031224,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031347,GO:0031349,GO:0031410,GO:0031625,GO:0031647,GO:0031667,GO:0031907,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031982,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032479,GO:0032481,GO:0032496,GO:0032501,GO:0032502,GO:0032647,GO:0032649,GO:0032653,GO:0032655,GO:0032675,GO:0032680,GO:0032727,GO:0032729,GO:0032733,GO:0032735,GO:0032755,GO:0032760,GO:0032879,GO:0032880,GO:0032943,GO:0032991,GO:0033036,GO:0033198,GO:0033218,GO:0033365,GO:0033554,GO:0033993,GO:0034185,GO:0034186,GO:0034514,GO:0034605,GO:0034613,GO:0034620,GO:0034622,GO:0034641,GO:0035966,GO:0035967,GO:0036293,GO:0036477,GO:0042026,GO:0042100,GO:0042110,GO:0042113,GO:0042220,GO:0042221,GO:0042277,GO:0042493,GO:0042542,GO:0042562,GO:0042579,GO:0042588,GO:0042886,GO:0042981,GO:0043025,GO:0043030,GO:0043032,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043170,GO:0043207,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0043231,GO:0043233,GO:0043235,GO:0043279,GO:0043280,GO:0043281,GO:0043523,GO:0043524,GO:0043559,GO:0043565,GO:0043627,GO:0043933,GO:0044085,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044297,GO:0044389,GO:0044403,GO:0044419,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044743,GO:0044877,GO:0045041,GO:0045088,GO:0045089,GO:0045121,GO:0045184,GO:0045190,GO:0045321,GO:0045785,GO:0045862,GO:0046483,GO:0046649,GO:0046651,GO:0046677,GO:0046683,GO:0046696,GO:0046907,GO:0046982,GO:0046983,GO:0048291,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050727,GO:0050729,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051087,GO:0051131,GO:0051171,GO:0051173,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051249,GO:0051251,GO:0051252,GO:0051336,GO:0051345,GO:0051384,GO:0051604,GO:0051641,GO:0051649,GO:0051702,GO:0051704,GO:0051707,GO:0051716,GO:0052547,GO:0052548,GO:0055085,GO:0060255,GO:0060359,GO:0060548,GO:0061077,GO:0065002,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070062,GO:0070201,GO:0070482,GO:0070585,GO:0070661,GO:0070727,GO:0070887,GO:0071310,GO:0071702,GO:0071704,GO:0071705,GO:0071806,GO:0071813,GO:0071814,GO:0071840,GO:0071865,GO:0071866,GO:0071944,GO:0072347,GO:0072594,GO:0072655,GO:0080090,GO:0080134,GO:0090087,GO:0090304,GO:0097159,GO:0097367,GO:0097458,GO:0097708,GO:0098589,GO:0098796,GO:0098805,GO:0098857,GO:0099503,GO:0140030,GO:1901214,GO:1901215,GO:1901360,GO:1901363,GO:1901564,GO:1901698,GO:1901700,GO:1903037,GO:1903039,GO:1903426,GO:1903427,GO:1903506,GO:1903530,GO:1903532,GO:1903555,GO:1903557,GO:1903561,GO:1904467,GO:1904469,GO:1904951,GO:1990542,GO:1990837,GO:2000112,GO:2000116,GO:2000377,GO:2000378,GO:2000778,GO:2001056,GO:2001141	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_156320_1	388413.ALPR1_08418	7.57e-86	258.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,47KMI@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_156322_1	1453501.JELR01000002_gene635	1.04e-51	185.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,464DC@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_195142_2	330214.NIDE0552	6.06e-30	120.0	COG2831@1|root,COG2831@2|Bacteria	2|Bacteria	U	hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF285,POTRA_2,ShlB
k59_77855_2	96561.Dole_1228	2.37e-45	152.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,42RPD@68525|delta/epsilon subdivisions,2WNI0@28221|Deltaproteobacteria,2MK1B@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
k59_940222_1	933262.AXAM01000021_gene478	4.81e-93	282.0	COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria,2MIH3@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
k59_195217_1	518766.Rmar_0949	2.2e-40	148.0	COG1763@1|root,COG1763@2|Bacteria,4PM6G@976|Bacteroidetes,1FK05@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Mo-molybdopterin cofactor biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_276546_1	1042377.AFPJ01000015_gene1595	8.39e-61	205.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,46C30@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,FAD_binding_6,NAD_binding_1,NAD_binding_8
k59_472462_1	1122185.N792_10720	7.14e-59	202.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1X42Y@135614|Xanthomonadales	135614|Xanthomonadales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HHH_5,Helicase_C,RecG_wedge
k59_1060071_1	1429851.X548_04910	1.2e-58	200.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria,1X3WH@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_1138477_1	9601.ENSPPYP00000011372	7.78e-65	207.0	COG0476@1|root,KOG2014@2759|Eukaryota,395DT@33154|Opisthokonta,3BH0I@33208|Metazoa,3CV84@33213|Bilateria,48B0Z@7711|Chordata,48ZM6@7742|Vertebrata,3JEIS@40674|Mammalia,35E3S@314146|Euarchontoglires,4MBCI@9443|Primates,4MWEN@9604|Hominidae	33208|Metazoa	O	ubiquitin-like modifier activating enzyme activity	SAE1	GO:0002376,GO:0002520,GO:0002682,GO:0002684,GO:0003674,GO:0003824,GO:0004839,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006464,GO:0006807,GO:0007275,GO:0007346,GO:0008022,GO:0008047,GO:0008150,GO:0008152,GO:0008641,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010646,GO:0010647,GO:0016567,GO:0016874,GO:0016877,GO:0016925,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0019948,GO:0023051,GO:0023056,GO:0030097,GO:0030234,GO:0031323,GO:0031326,GO:0031347,GO:0031349,GO:0031510,GO:0031624,GO:0031974,GO:0031981,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0033134,GO:0034121,GO:0034123,GO:0034124,GO:0034126,GO:0036211,GO:0042592,GO:0043008,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044388,GO:0044390,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045088,GO:0045089,GO:0046982,GO:0046983,GO:0048513,GO:0048518,GO:0048522,GO:0048534,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0048872,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0051090,GO:0051091,GO:0051092,GO:0051171,GO:0051252,GO:0051726,GO:0060216,GO:0060255,GO:0061484,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070647,GO:0071704,GO:0080090,GO:0080134,GO:0098772,GO:1901564,GO:1902494,GO:1903506,GO:2000112,GO:2001141	6.2.1.45	ko:K10684	ko04120,map04120	-	-	-	ko00000,ko00001,ko01000,ko04121	-	-	-	ThiF
k59_511749_1	391595.RLO149_c037010	3.64e-92	286.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	MA20_04810	-	3.5.1.82	ko:K01461	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_3
k59_41375_1	335543.Sfum_2102	3.65e-95	291.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,43BJP@68525|delta/epsilon subdivisions,2WJWZ@28221|Deltaproteobacteria,2MQSJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2,4.3.1.1	ko:K01679,ko:K01744	ko00020,ko00250,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00250,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R00490,R01082	RC00316,RC00443,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_550923_2	203122.Sde_3573	9.49e-09	58.2	COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria,465H2@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	COG3156 Type II secretory pathway, component PulK	gspK	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k59_433285_1	1144275.COCOR_06099	1.17e-56	192.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_864366_1	1173029.JH980292_gene562	7.09e-08	51.2	COG3288@1|root,COG3288@2|Bacteria,1G711@1117|Cyanobacteria,1HBSJ@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
k59_864366_2	1121406.JAEX01000007_gene2381	5.18e-32	125.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,42NHS@68525|delta/epsilon subdivisions,2WJHI@28221|Deltaproteobacteria,2MAE5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	NAD(P) transhydrogenase beta subunit	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_1099479_1	335543.Sfum_3291	1.24e-65	218.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MQ86@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_629227_1	760117.JN27_21740	1.34e-88	270.0	COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,2WBK9@28216|Betaproteobacteria,4760H@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
k59_1060112_1	1304275.C41B8_11553	1.06e-97	300.0	COG3425@1|root,COG3425@2|Bacteria,1MU4K@1224|Proteobacteria,1S16F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	synthase	-	-	2.3.3.10	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
k59_629234_1	265072.Mfla_1109	8.97e-65	207.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,2KM5R@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
k59_629240_1	666685.R2APBS1_0882	8.46e-31	122.0	COG0642@1|root,COG0642@2|Bacteria,1R54G@1224|Proteobacteria,1RWXF@1236|Gammaproteobacteria,1X4MP@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_394416_1	880072.Desac_0484	1.73e-133	395.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2MQ9M@213462|Syntrophobacterales	28221|Deltaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
k59_903502_1	1148.1653166	9.56e-61	200.0	COG1305@1|root,COG1305@2|Bacteria,1G2WU@1117|Cyanobacteria,1H6FT@1142|Synechocystis	1117|Cyanobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_394427_1	933262.AXAM01000023_gene638	3.38e-85	268.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	-	-	-	-	-	-	-	-	-	-	MM_CoA_mutase
k59_982159_1	562970.Btus_1123	1.5e-10	65.1	COG3284@1|root,COG3284@2|Bacteria,1VHQN@1239|Firmicutes	1239|Firmicutes	KQ	sigma54 specific, transcriptional regulator, Fis family	acoR	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,PAS,Sigma54_activat
k59_1099521_1	379066.GAU_3726	2.1e-35	134.0	COG3666@1|root,COG3666@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_668491_1	396588.Tgr7_0821	5.87e-07	55.5	COG0518@1|root,COG0518@2|Bacteria,1MYXC@1224|Proteobacteria,1SJVW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	GMP synthase (glutamine-hydrolyzing) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_903511_1	1121396.KB892902_gene2306	1.95e-62	201.0	COG0619@1|root,COG0619@2|Bacteria,1RJIT@1224|Proteobacteria,42RU5@68525|delta/epsilon subdivisions,2WNB7@28221|Deltaproteobacteria,2MJTN@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TIGRFAM cobalt ABC transporter, permease protein CbiQ	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
k59_315765_1	1122139.KB907869_gene936	3.31e-35	127.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,1XJIV@135619|Oceanospirillales	135619|Oceanospirillales	E	COG2755 Lysophospholipase L1 and related esterases	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
k59_511877_1	555079.Toce_1087	2.23e-21	96.7	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,42G77@68295|Thermoanaerobacterales	186801|Clostridia	D	tyrosine recombinase XerC	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_433371_1	77586.LPERR07G07600.1	2.5e-14	76.6	COG1473@1|root,2QQEM@2759|Eukaryota,37JVC@33090|Viridiplantae,3GAU7@35493|Streptophyta,3KQN6@4447|Liliopsida,3I8AP@38820|Poales	35493|Streptophyta	S	Peptidase dimerisation domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0008150,GO:0008152,GO:0009850,GO:0009987,GO:0010178,GO:0010210,GO:0010211,GO:0010817,GO:0012505,GO:0016787,GO:0016810,GO:0042445,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0065007,GO:0065008	-	ko:K14664	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_198330_1	933262.AXAM01000025_gene3408	3.05e-70	217.0	COG1751@1|root,COG1751@2|Bacteria,1RBXI@1224|Proteobacteria,42R3D@68525|delta/epsilon subdivisions,2WMRV@28221|Deltaproteobacteria,2MJGF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyruvate kinase, alpha/beta domain	-	-	-	ko:K09126	-	-	-	-	ko00000	-	-	-	PK_C
k59_159082_1	349163.Acry_2608	2.54e-89	271.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2TTC4@28211|Alphaproteobacteria,2JQCB@204441|Rhodospirillales	204441|Rhodospirillales	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_80969_1	1278073.MYSTI_07789	4.4e-11	68.6	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,43785@68525|delta/epsilon subdivisions,2X2AK@28221|Deltaproteobacteria,2Z1TK@29|Myxococcales	28221|Deltaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_746884_1	1122194.AUHU01000003_gene2388	4.08e-72	232.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,1S0KD@1236|Gammaproteobacteria,466F0@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Biotin-lipoyl like	acrE	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1021386_1	933262.AXAM01000010_gene1386	1.84e-61	194.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,42U68@68525|delta/epsilon subdivisions,2WQJS@28221|Deltaproteobacteria,2MJKI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
k59_668568_1	1232437.KL661965_gene3270	2.23e-134	399.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MJNF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_786139_1	862908.BMS_3090	1.29e-14	72.4	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	fjo27	-	-	-	-	-	-	-	-	-	-	-	VanZ
k59_1138630_1	667014.Thein_0927	2.99e-92	285.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2GHHW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_551082_1	1124780.ANNU01000016_gene1821	1.26e-18	89.7	COG0729@1|root,COG0729@2|Bacteria,4NMUN@976|Bacteroidetes,47Y2C@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
k59_551082_2	616991.JPOO01000003_gene1308	8.35e-14	66.2	2A450@1|root,30SQ1@2|Bacteria,4PEPS@976|Bacteroidetes,1IF9F@117743|Flavobacteriia,23HQC@178469|Arenibacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_511986_1	335543.Sfum_4070	6.02e-75	233.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42MKP@68525|delta/epsilon subdivisions,2WJU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_198390_1	935567.JAES01000003_gene234	4.69e-81	252.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1X45S@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_629355_1	583355.Caka_2183	1.18e-63	209.0	COG0577@1|root,COG0577@2|Bacteria,46TM1@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	MacB_PCD
k59_355126_1	593750.Metfor_2049	2.51e-68	216.0	COG4294@1|root,arCOG01898@2157|Archaea,2XVT2@28890|Euryarchaeota	28890|Euryarchaeota	L	UV-endonuclease UvdE	uvsE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
k59_1021418_1	391615.ABSJ01000005_gene583	4.63e-68	214.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1J4DJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_707656_1	1077974.GOEFS_113_00020	6.13e-22	98.2	COG1020@1|root,COG1020@2|Bacteria,2GPHZ@201174|Actinobacteria,4GBXH@85026|Gordoniaceae	201174|Actinobacteria	I	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
k59_1178060_1	1177928.TH2_08086	0.000608	47.8	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,2TTAH@28211|Alphaproteobacteria,2JTRQ@204441|Rhodospirillales	204441|Rhodospirillales	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_512014_1	1211579.PP4_27050	1.48e-22	102.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RNM8@1236|Gammaproteobacteria,1YV7F@136845|Pseudomonas putida group	1236|Gammaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k59_81045_1	1500259.JQLD01000002_gene3008	6.04e-15	81.3	COG2202@1|root,COG2982@1|root,COG3209@1|root,COG3210@1|root,COG5295@1|root,COG2202@2|Bacteria,COG2982@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG5295@2|Bacteria,1QUXB@1224|Proteobacteria,2TWTY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347
k59_433457_1	1197906.CAJQ02000044_gene1817	1.19e-81	257.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2TR5N@28211|Alphaproteobacteria,3JR6B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	MA20_04440	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
k59_81051_1	1121403.AUCV01000007_gene1244	2.08e-106	331.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MHRD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_825378_1	570967.JMLV01000008_gene1335	1.19e-87	267.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TSBB@28211|Alphaproteobacteria,2JR85@204441|Rhodospirillales	204441|Rhodospirillales	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
k59_903666_1	9606.ENSP00000357076	2.12e-143	405.0	COG5199@1|root,KOG2046@2759|Eukaryota,39VQE@33154|Opisthokonta,3BA7U@33208|Metazoa,3CVBH@33213|Bilateria,480TR@7711|Chordata,4969J@7742|Vertebrata,3J2JY@40674|Mammalia,35D29@314146|Euarchontoglires,4MDR0@9443|Primates,4N1NY@9604|Hominidae	33208|Metazoa	Z	Calponin family repeat	TAGLN2	GO:0002576,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0006887,GO:0008150,GO:0009888,GO:0009987,GO:0016192,GO:0030154,GO:0030855,GO:0032502,GO:0032940,GO:0044424,GO:0044444,GO:0044464,GO:0045055,GO:0046903,GO:0048856,GO:0048869,GO:0051179,GO:0051234,GO:0060429	-	ko:K20526	-	-	-	-	ko00000,ko04131	-	-	-	CH,Calponin
k59_942983_1	690850.Desaf_2364	5.84e-59	201.0	28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_41603_1	610130.Closa_2542	8.37e-06	53.9	COG3437@1|root,COG5000@1|root,COG3437@2|Bacteria,COG5000@2|Bacteria,1UJKB@1239|Firmicutes,25F57@186801|Clostridia,221NE@1506553|Lachnoclostridium	186801|Clostridia	T	PAS domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,GAF_2,GGDEF,HAMP,HATPase_c,HD_5,HisKA,Response_reg,dCache_1
k59_81108_1	158189.SpiBuddy_1525	1.58e-14	78.2	COG0587@1|root,COG0587@2|Bacteria,2J5DA@203691|Spirochaetes	203691|Spirochaetes	L	DNA polymerase	-	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_668659_1	225849.swp_3123	7.34e-08	56.2	29JGM@1|root,306DZ@2|Bacteria,1RFV2@1224|Proteobacteria,1S5BI@1236|Gammaproteobacteria,2QB8W@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
k59_1178142_3	617140.AJZE01000074_gene979	3.17e-08	55.5	COG3659@1|root,COG3659@2|Bacteria,1R8TI@1224|Proteobacteria,1S21B@1236|Gammaproteobacteria,1XVR4@135623|Vibrionales	135623|Vibrionales	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
k59_707718_1	330214.NIDE0473	8.23e-75	235.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
k59_41620_1	338966.Ppro_3708	1.92e-112	336.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_982438_1	744980.TRICHSKD4_2949	4.5e-30	120.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TQJJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_1099774_1	626418.bglu_2g09310	3.7e-44	157.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,2VZPV@28216|Betaproteobacteria,1K4NM@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Class-II DAHP synthetase family	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
k59_355262_1	1158601.I585_01621	2.48e-14	73.6	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,4B185@81852|Enterococcaceae	91061|Bacilli	E	AAA domain, putative AbiEii toxin, Type IV TA system	yxeO	-	-	ko:K16963	ko02010,map02010	M00586	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
k59_668730_1	379731.PST_0549	5.28e-54	190.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1Z0AH@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_707776_1	1121451.DESAM_23071	2.95e-41	143.0	COG2204@1|root,COG2204@2|Bacteria,1RCHU@1224|Proteobacteria,42QWT@68525|delta/epsilon subdivisions,2WN23@28221|Deltaproteobacteria,2MAFK@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,STAS,STAS_2
k59_707776_2	1265505.ATUG01000001_gene4001	1.26e-23	92.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,42X24@68525|delta/epsilon subdivisions,2WSTX@28221|Deltaproteobacteria,2MM25@213118|Desulfobacterales	28221|Deltaproteobacteria	O	TIGRFAM hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
k59_1217097_1	933262.AXAM01000001_gene442	1.34e-32	115.0	COG2119@1|root,COG2119@2|Bacteria,1PP1W@1224|Proteobacteria,42XF8@68525|delta/epsilon subdivisions,2WTC8@28221|Deltaproteobacteria,2MNT5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
k59_1217097_2	439235.Dalk_0905	1.42e-30	115.0	COG1032@1|root,COG1032@2|Bacteria,1P9J0@1224|Proteobacteria,42MWG@68525|delta/epsilon subdivisions,2WIV5@28221|Deltaproteobacteria,2MI1A@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_472837_1	1254432.SCE1572_01820	7.89e-08	52.4	COG3791@1|root,COG3791@2|Bacteria,1PSHM@1224|Proteobacteria,4355R@68525|delta/epsilon subdivisions,2WZGP@28221|Deltaproteobacteria,2Z244@29|Myxococcales	28221|Deltaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_472837_2	1123501.KB902283_gene2340	1.12e-33	126.0	COG0687@1|root,COG0687@2|Bacteria,1NKD7@1224|Proteobacteria,2TYST@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Extracellular solute-binding protein	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
k59_514964_1	396588.Tgr7_1267	2.47e-34	129.0	COG0247@1|root,COG1145@1|root,COG0247@2|Bacteria,COG1145@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1WWK6@135613|Chromatiales	135613|Chromatiales	C	PFAM Cysteine-rich	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_671303_1	9606.ENSP00000265056	9.99e-133	401.0	COG1241@1|root,KOG0477@2759|Eukaryota,38B55@33154|Opisthokonta,3BE4J@33208|Metazoa,3CYCH@33213|Bilateria,48080@7711|Chordata,495T4@7742|Vertebrata,3JCB2@40674|Mammalia,35N8U@314146|Euarchontoglires,4MIGP@9443|Primates,4MVE5@9604|Hominidae	33208|Metazoa	L	Mini-chromosome maintenance protein 2	MCM2	GO:0000082,GO:0000228,GO:0000278,GO:0000785,GO:0000793,GO:0000808,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005664,GO:0005694,GO:0005737,GO:0005856,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006275,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006725,GO:0006807,GO:0006915,GO:0006996,GO:0007049,GO:0007275,GO:0007423,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0012501,GO:0015630,GO:0016043,GO:0019219,GO:0019222,GO:0019899,GO:0022402,GO:0022607,GO:0030174,GO:0030261,GO:0031323,GO:0031326,GO:0031497,GO:0031974,GO:0031981,GO:0032392,GO:0032501,GO:0032502,GO:0032508,GO:0032991,GO:0034097,GO:0034622,GO:0034641,GO:0034645,GO:0034728,GO:0042221,GO:0042393,GO:0042555,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0043583,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0045120,GO:0046483,GO:0048513,GO:0048731,GO:0048839,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051276,GO:0051716,GO:0060255,GO:0065003,GO:0065004,GO:0065007,GO:0070013,GO:0070670,GO:0070887,GO:0071103,GO:0071310,GO:0071345,GO:0071353,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090102,GO:0090304,GO:0090329,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1903047,GO:1990837,GO:2000112	3.6.4.12	ko:K02540	ko03030,ko04110,ko04111,ko04113,map03030,map04110,map04111,map04113	M00285	-	-	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036	-	-	-	MCM,MCM2_N,MCM_N,MCM_OB
k59_436049_1	323098.Nwi_0283	3.15e-90	295.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,3JUU3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_514971_1	713587.THITH_12510	7.23e-51	189.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
k59_593086_1	1265505.ATUG01000001_gene4056	1.23e-20	90.9	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2MHUE@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_593086_2	1265505.ATUG01000001_gene4057	5.1e-76	235.0	COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,42PNV@68525|delta/epsilon subdivisions,2WJVJ@28221|Deltaproteobacteria,2MK8B@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1141446_1	322710.Avin_29880	3.68e-14	75.1	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Multidrug efflux pump	pmpM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_10476_1	1125863.JAFN01000001_gene78	4.65e-137	397.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MR6@68525|delta/epsilon subdivisions,2WITP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_10480_1	335284.Pcryo_2123	6.72e-88	271.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria,3NJKT@468|Moraxellaceae	1236|Gammaproteobacteria	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
k59_911262_1	317025.Tcr_1260	2.76e-51	174.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,46068@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_402855_1	2340.JV46_11900	1.38e-12	66.6	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,1J5J9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the dihydroorotate dehydrogenase family	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,NAD_binding_1
k59_402855_2	95619.PM1_0201870	4.6e-41	139.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_441550_1	1280949.HAD_16642	5.18e-23	98.6	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria,43ZIX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_441550_2	1041159.AZUW01000007_gene5305	2.56e-58	188.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VEU2@28211|Alphaproteobacteria,4BEAI@82115|Rhizobiaceae	28211|Alphaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran
k59_1107717_1	794903.OPIT5_22915	1.03e-72	239.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA,VWA_3
k59_49783_1	887929.HMP0721_2207	2.3e-89	279.0	COG1850@1|root,COG1850@2|Bacteria,1TSZQ@1239|Firmicutes,2482N@186801|Clostridia,25YA5@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the RuBisCO large chain family	mtnW	-	5.3.2.5	ko:K08965	ko00270,ko01100,map00270,map01100	M00034	R07393	RC02421	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_323871_2	1121405.dsmv_2448	2.1e-18	82.4	COG1018@1|root,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	fpr	GO:0000166,GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004324,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006000,GO:0006001,GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0016043,GO:0016052,GO:0016226,GO:0016491,GO:0016730,GO:0016731,GO:0019318,GO:0019320,GO:0022607,GO:0031163,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0055114,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901575,GO:1901700	1.18.1.2,1.19.1.1	ko:K00528,ko:K05784	ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220	M00551	R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110,R10159	RC00270,RC01378,RC01450,RC01910	br01602,ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_3072,iEcSMS35_1347.EcSMS35_4364,iYL1228.KPN_04002	FAD_binding_6,NAD_binding_1
k59_402863_1	1188256.BASI01000002_gene3774	1.43e-78	245.0	COG3666@1|root,COG3666@2|Bacteria,1QW5T@1224|Proteobacteria,2TWNW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_598501_1	1443111.JASG01000004_gene1143	2.51e-39	145.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria,3ZW5Q@60136|Sulfitobacter	28211|Alphaproteobacteria	C	catalyzes NAD -dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component	lpd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_10496_1	545276.KB898725_gene882	1.19e-49	177.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1WWQV@135613|Chromatiales	135613|Chromatiales	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_716420_1	1121405.dsmv_1087	6.18e-66	224.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,2MINK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_323881_2	1163617.SCD_n01434	1.41e-28	114.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1MUAK@1224|Proteobacteria,2WGJC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_167267_1	1120966.AUBU01000008_gene2392	8.38e-112	347.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47N2K@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_284771_1	864051.BurJ1DRAFT_4175	2.18e-60	208.0	COG3303@1|root,COG3303@2|Bacteria,1PEVM@1224|Proteobacteria,2VMWI@28216|Betaproteobacteria,1KN2G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_10530_1	717231.Flexsi_0308	0.000297	48.5	COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria	2|Bacteria	P	domain protein	yfbS	-	-	ko:K03281,ko:K07085	-	-	-	-	ko00000	2.A.49,2.A.81	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_716456_1	27679.XP_010344602.1	3.18e-63	196.0	KOG1761@1|root,KOG1761@2759|Eukaryota,3A8FZ@33154|Opisthokonta,3C01W@33208|Metazoa,3E43K@33213|Bilateria,48QSC@7711|Chordata,49MCA@7742|Vertebrata,3JPUA@40674|Mammalia,35U9G@314146|Euarchontoglires,4MJF5@9443|Primates	33208|Metazoa	U	signal recognition particle	SRP14	GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005786,GO:0005829,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0006887,GO:0006955,GO:0008104,GO:0008150,GO:0008312,GO:0009987,GO:0012505,GO:0015031,GO:0015833,GO:0016192,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034774,GO:0036230,GO:0042119,GO:0042221,GO:0042493,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045047,GO:0045055,GO:0045184,GO:0045321,GO:0046903,GO:0046907,GO:0048500,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060205,GO:0070013,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097708,GO:0099503,GO:0101002,GO:1901363,GO:1904813,GO:1990904	-	ko:K03104	ko03060,map03060	-	-	-	ko00000,ko00001,ko02044	3.A.5.9	-	-	SRP14
k59_1107758_2	335543.Sfum_1753	6.8e-19	87.8	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria,2MRB3@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	transport system involved in gliding motility auxiliary component-like	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
k59_1146731_1	10141.ENSCPOP00000019509	8.71e-119	347.0	COG0500@1|root,KOG1499@2759|Eukaryota,38BN9@33154|Opisthokonta,3BEAC@33208|Metazoa,3CS0B@33213|Bilateria,482MA@7711|Chordata,48X98@7742|Vertebrata,3JB0D@40674|Mammalia,359HZ@314146|Euarchontoglires,4Q75J@9989|Rodentia	33208|Metazoa	B	PRMT5 arginine-N-methyltransferase	PRMT1	GO:0000075,GO:0000077,GO:0000166,GO:0000278,GO:0001701,GO:0001889,GO:0001932,GO:0001933,GO:0001934,GO:0002682,GO:0002683,GO:0002684,GO:0003674,GO:0003676,GO:0003677,GO:0003712,GO:0003713,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006325,GO:0006355,GO:0006464,GO:0006479,GO:0006807,GO:0006950,GO:0006974,GO:0006977,GO:0006979,GO:0006996,GO:0007049,GO:0007093,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007346,GO:0007399,GO:0007552,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008284,GO:0008327,GO:0008340,GO:0008469,GO:0008757,GO:0009266,GO:0009314,GO:0009408,GO:0009411,GO:0009416,GO:0009605,GO:0009628,GO:0009790,GO:0009792,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010259,GO:0010286,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010646,GO:0010647,GO:0010883,GO:0010948,GO:0016020,GO:0016043,GO:0016273,GO:0016274,GO:0016275,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018193,GO:0018195,GO:0018216,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0019919,GO:0022008,GO:0022402,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030154,GO:0030182,GO:0030330,GO:0030519,GO:0031056,GO:0031099,GO:0031100,GO:0031175,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031400,GO:0031401,GO:0031570,GO:0031571,GO:0031667,GO:0031974,GO:0031981,GO:0032091,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032872,GO:0032874,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033044,GO:0033554,GO:0034708,GO:0034709,GO:0034969,GO:0035241,GO:0035242,GO:0035246,GO:0035247,GO:0035556,GO:0036094,GO:0036211,GO:0042054,GO:0042127,GO:0042325,GO:0042326,GO:0042327,GO:0042594,GO:0042770,GO:0042802,GO:0043009,GO:0043021,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0043408,GO:0043410,GO:0043412,GO:0043414,GO:0043565,GO:0043933,GO:0043985,GO:0044020,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044773,GO:0044774,GO:0044783,GO:0044819,GO:0044877,GO:0045595,GO:0045596,GO:0045597,GO:0045637,GO:0045638,GO:0045639,GO:0045646,GO:0045648,GO:0045652,GO:0045653,GO:0045786,GO:0045787,GO:0045893,GO:0045930,GO:0045935,GO:0045936,GO:0045937,GO:0046984,GO:0046985,GO:0048037,GO:0048273,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048580,GO:0048583,GO:0048584,GO:0048666,GO:0048699,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051019,GO:0051093,GO:0051094,GO:0051098,GO:0051100,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0051726,GO:0060255,GO:0060341,GO:0061008,GO:0061062,GO:0061065,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070302,GO:0070304,GO:0071156,GO:0071158,GO:0071704,GO:0071840,GO:0072331,GO:0072395,GO:0072401,GO:0072413,GO:0072422,GO:0072431,GO:0080090,GO:0080134,GO:0080135,GO:0090068,GO:0097159,GO:0097421,GO:0120036,GO:0140096,GO:0140110,GO:1900180,GO:1900182,GO:1900744,GO:1900745,GO:1901265,GO:1901363,GO:1901564,GO:1901681,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902275,GO:1902400,GO:1902402,GO:1902403,GO:1902494,GO:1902531,GO:1902533,GO:1902680,GO:1902806,GO:1902807,GO:1903047,GO:1903506,GO:1903508,GO:1903706,GO:1903707,GO:1903708,GO:1903827,GO:1903829,GO:1904047,GO:1905909,GO:1905952,GO:1990234,GO:2000026,GO:2000045,GO:2000112,GO:2000134,GO:2001141	2.1.1.319	ko:K11434,ko:K11439	ko04068,ko04922,map04068,map04922	-	R11216,R11217,R11219	RC00003,RC02120,RC03388,RC03390	ko00000,ko00001,ko01000,ko03036	-	-	-	Methyltransf_25,PrmA
k59_637554_1	56780.SYN_00898	2.16e-14	71.6	COG3816@1|root,COG3816@2|Bacteria,1Q2AK@1224|Proteobacteria,437X9@68525|delta/epsilon subdivisions,2X372@28221|Deltaproteobacteria,2MS8V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1285)	-	-	-	ko:K09986	-	-	-	-	ko00000	-	-	-	DUF1285
k59_89728_1	933262.AXAM01000023_gene642	1.35e-42	149.0	COG2820@1|root,COG2820@2|Bacteria,1QW1B@1224|Proteobacteria,42R3X@68525|delta/epsilon subdivisions,2WP50@28221|Deltaproteobacteria,2MKA8@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM purine or other phosphorylase family 1	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
k59_402974_1	1215092.PA6_016_00390	3.36e-25	108.0	COG2199@1|root,COG3706@2|Bacteria,1MZQ8@1224|Proteobacteria,1RZJU@1236|Gammaproteobacteria,1YHR1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_480791_1	1232437.KL661958_gene2862	1.65e-17	77.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1,MFS_1_like,Sugar_tr
k59_480791_2	251229.Chro_3913	5.1e-06	48.9	COG2267@1|root,COG2267@2|Bacteria,1GR0Y@1117|Cyanobacteria	1117|Cyanobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
k59_284845_1	1040983.AXAE01000007_gene4163	4.54e-76	240.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_402983_1	1430440.MGMSRv2_3789	1.59e-44	157.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2TTXT@28211|Alphaproteobacteria,2JSFC@204441|Rhodospirillales	204441|Rhodospirillales	L	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_167359_1	56780.SYN_01041	7.27e-80	253.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2MQWN@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Biotin carboxylase C-terminal domain	accC	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
k59_994605_2	1265505.ATUG01000001_gene4505	1.39e-16	78.2	COG0509@1|root,COG0509@2|Bacteria,1RC80@1224|Proteobacteria,42R79@68525|delta/epsilon subdivisions,2WN04@28221|Deltaproteobacteria,2MJJZ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
k59_1034056_1	717785.HYPMC_2411	7.93e-54	172.0	COG4957@1|root,COG4957@2|Bacteria,1RGUW@1224|Proteobacteria,2U99M@28211|Alphaproteobacteria,3N700@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	mucR	-	-	-	-	-	-	-	-	-	-	-	ROS_MUCR
k59_130552_1	717785.HYPMC_0944	8.05e-78	240.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria,3N6CK@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_601070_1	1255043.TVNIR_1568	5.21e-17	82.4	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1WXED@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_444024_1	987059.RBXJA2T_02215	1.47e-57	183.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,1KKSV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_679136_1	439235.Dalk_5066	1.7e-51	182.0	COG0247@1|root,COG1150@1|root,COG2181@1|root,COG0247@2|Bacteria,COG1150@2|Bacteria,COG2181@2|Bacteria,1R44N@1224|Proteobacteria,42NTE@68525|delta/epsilon subdivisions,2WJN8@28221|Deltaproteobacteria,2MJEV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,Nitrate_red_gam
k59_1034090_1	1265505.ATUG01000003_gene201	1.75e-69	224.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2MHTS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
k59_366121_1	1158762.KB898039_gene1762	2.07e-78	237.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1WWTG@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, E subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k59_366121_2	1255043.TVNIR_3123	5.38e-13	67.8	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_796260_1	9606.ENSP00000345672	2.11e-136	390.0	COG4870@1|root,KOG1543@2759|Eukaryota,38F8F@33154|Opisthokonta,3BI1S@33208|Metazoa,3CS39@33213|Bilateria,485TY@7711|Chordata,497GR@7742|Vertebrata,3J20Q@40674|Mammalia,35KQZ@314146|Euarchontoglires,4MGQH@9443|Primates,4N4E3@9604|Hominidae	33208|Metazoa	O	cellular response to thyroid hormone stimulus	CTSB	GO:0000003,GO:0000323,GO:0001775,GO:0001890,GO:0001893,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003006,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004252,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005764,GO:0005768,GO:0005773,GO:0005775,GO:0005886,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006914,GO:0006950,GO:0006955,GO:0007275,GO:0007276,GO:0007283,GO:0007517,GO:0007519,GO:0007565,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008234,GO:0008236,GO:0009056,GO:0009057,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009888,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0010243,GO:0010941,GO:0012501,GO:0012505,GO:0014070,GO:0014075,GO:0014706,GO:0016020,GO:0016032,GO:0016192,GO:0016324,GO:0016787,GO:0017171,GO:0019058,GO:0019538,GO:0019953,GO:0022414,GO:0030141,GO:0030154,GO:0030163,GO:0030260,GO:0030574,GO:0030855,GO:0030984,GO:0031410,GO:0031904,GO:0031974,GO:0031981,GO:0031982,GO:0032501,GO:0032502,GO:0032504,GO:0032870,GO:0032940,GO:0032963,GO:0033218,GO:0034097,GO:0034284,GO:0036019,GO:0036021,GO:0036230,GO:0042119,GO:0042221,GO:0042277,GO:0042383,GO:0042493,GO:0042981,GO:0043067,GO:0043170,GO:0043202,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043394,GO:0043434,GO:0043621,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044403,GO:0044409,GO:0044419,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044433,GO:0044437,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0044706,GO:0044877,GO:0045055,GO:0045177,GO:0045321,GO:0045471,GO:0046677,GO:0046697,GO:0046718,GO:0046903,GO:0048232,GO:0048471,GO:0048513,GO:0048519,GO:0048523,GO:0048608,GO:0048609,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051603,GO:0051701,GO:0051704,GO:0051716,GO:0051806,GO:0051828,GO:0060135,GO:0060429,GO:0060537,GO:0060538,GO:0060548,GO:0061061,GO:0061458,GO:0061919,GO:0065007,GO:0070011,GO:0070013,GO:0070670,GO:0070887,GO:0071214,GO:0071260,GO:0071310,GO:0071495,GO:0071496,GO:0071704,GO:0071944,GO:0097066,GO:0097067,GO:0097305,GO:0097367,GO:0097708,GO:0098552,GO:0098590,GO:0099503,GO:0101002,GO:0104004,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901652,GO:1901698,GO:1901700,GO:1904813	3.4.22.1	ko:K01363	ko04140,ko04142,ko04210,ko04612,ko04621,ko04924,map04140,map04142,map04210,map04612,map04621,map04924	-	-	-	ko00000,ko00001,ko00536,ko01000,ko01002,ko03110,ko04147	-	-	-	Peptidase_C1,Propeptide_C1
k59_1149227_1	378806.STAUR_8186	2.02e-43	159.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,43BBS@68525|delta/epsilon subdivisions,2X6QY@28221|Deltaproteobacteria,2YU79@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_326395_1	395493.BegalDRAFT_0212	4.7e-28	112.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,460AT@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_326395_2	760117.JN27_04155	6.07e-48	158.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,472VR@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, mono-heme subunit/FixO	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_639939_1	941449.dsx2_1445	1.19e-68	220.0	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,42QQ7@68525|delta/epsilon subdivisions,2WN8Z@28221|Deltaproteobacteria,2M8UD@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k59_326418_1	290398.Csal_0621	1.46e-64	218.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1XI9K@135619|Oceanospirillales	135619|Oceanospirillales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_1188729_1	1121441.AUCX01000001_gene2663	1.63e-25	109.0	28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,42Z58@68525|delta/epsilon subdivisions,2WTW4@28221|Deltaproteobacteria,2M8HG@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_679198_1	706587.Desti_3036	5.78e-87	270.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,42NUH@68525|delta/epsilon subdivisions,2WISE@28221|Deltaproteobacteria,2MQ7F@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase	-	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
k59_366174_1	1123072.AUDH01000022_gene1099	1.49e-94	283.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,2JQ2Q@204441|Rhodospirillales	204441|Rhodospirillales	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
k59_444107_1	264201.pc1028	3.79e-15	73.2	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	insC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0009279,GO:0009297,GO:0009987,GO:0015267,GO:0015288,GO:0015473,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0022803,GO:0022829,GO:0022857,GO:0030030,GO:0030031,GO:0030312,GO:0030313,GO:0031975,GO:0043711,GO:0044085,GO:0044424,GO:0044444,GO:0044462,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071840,GO:0071944	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_601174_1	251229.Chro_4347	3.18e-60	213.0	COG2770@1|root,COG3322@1|root,COG3852@1|root,COG5001@1|root,COG2770@2|Bacteria,COG3322@2|Bacteria,COG3852@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,3VHU5@52604|Pleurocapsales	1117|Cyanobacteria	T	Diguanylate cyclase (GGDEF domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS_3,PAS_4,PAS_9
k59_130676_1	748449.Halha_0265	3.61e-56	188.0	COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,248GW@186801|Clostridia	186801|Clostridia	G	family 16	bglA3	-	-	-	-	-	-	-	-	-	-	-	Big_2,CW_binding_1,Glyco_hydro_16,RicinB_lectin_2
k59_1188819_1	261292.Nit79A3_1919	1.02e-57	183.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,2VTIQ@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_1070737_1	879212.DespoDRAFT_02969	2e-63	208.0	COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria,2MIH3@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
k59_994870_1	1385935.N836_09965	5.72e-08	59.3	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria,1HDU6@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
k59_796411_1	1536773.R70331_22380	5.84e-08	54.7	COG0454@1|root,COG0454@2|Bacteria,1UIIV@1239|Firmicutes,4HKSV@91061|Bacilli,26WZ3@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Acetyltransf_7
k59_796411_2	697282.Mettu_3211	1.48e-12	68.6	COG1361@1|root,COG1664@1|root,COG3210@1|root,COG1361@2|Bacteria,COG1664@2|Bacteria,COG3210@2|Bacteria,1PGPQ@1224|Proteobacteria,1S5UG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
k59_1188845_1	1121405.dsmv_3401	2.04e-76	245.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2MI8S@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_913861_1	1417296.U879_14150	1.24e-12	66.2	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TT0P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_913861_2	571166.KI421509_gene2609	1.57e-58	192.0	COG1177@1|root,COG1177@2|Bacteria,1MUQD@1224|Proteobacteria,2TS3C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type spermidine putrescine transport system, permease component	potC	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
k59_209056_1	1121403.AUCV01000066_gene4134	8.4e-06	48.1	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,42R3Z@68525|delta/epsilon subdivisions,2WN4D@28221|Deltaproteobacteria,2MJKG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
k59_326550_1	90813.JQMT01000001_gene1669	1.35e-86	263.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria,463S8@72273|Thiotrichales	72273|Thiotrichales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
k59_640095_2	555778.Hneap_0515	2.57e-49	160.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria,1WYZY@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
k59_640095_3	765914.ThisiDRAFT_0027	1.35e-65	202.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1WY6S@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
k59_52210_1	933262.AXAM01000017_gene3127	1.83e-39	138.0	COG0546@1|root,COG0546@2|Bacteria,1MY9Y@1224|Proteobacteria,42SSC@68525|delta/epsilon subdivisions,2WN7Q@28221|Deltaproteobacteria,2MKDC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_953597_1	44251.PDUR_21255	6.04e-85	275.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,26TK1@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_366302_2	795359.TOPB45_0627	5.46e-38	132.0	COG2905@1|root,COG2905@2|Bacteria,2GHVH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_1188870_1	1121405.dsmv_1449	1.5e-140	405.0	COG0674@1|root,COG0674@2|Bacteria,1MWCI@1224|Proteobacteria,42NJY@68525|delta/epsilon subdivisions,2WIW3@28221|Deltaproteobacteria,2MHPN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	vorA	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1307	PFOR_II,POR_N
k59_561757_1	983545.Glaag_1324	6.26e-40	141.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,1RS0G@1236|Gammaproteobacteria,464K6@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription	pspA	GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
k59_679357_2	696281.Desru_1825	9.11e-54	172.0	COG3603@1|root,COG3603@2|Bacteria,1V9Y8@1239|Firmicutes,24JKN@186801|Clostridia,2663Q@186807|Peptococcaceae	186801|Clostridia	S	ACT domain	-	-	-	ko:K09707	-	-	-	-	ko00000	-	-	-	ACT_7
k59_326585_1	1121878.AUGL01000021_gene2815	2.5e-149	438.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_326585_2	583355.Caka_2179	2.99e-08	54.7	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
k59_679361_1	1268635.Loa_02324	1.53e-78	251.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1JCE1@118969|Legionellales	118969|Legionellales	J	arginyl-tRNA aminoacylation	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_13170_1	555088.DealDRAFT_1964	1.97e-48	166.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,42JKV@68298|Syntrophomonadaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_406514_1	269797.Mbar_A3073	1.45e-61	207.0	COG3119@1|root,arCOG02791@2157|Archaea,2Y8G8@28890|Euryarchaeota,2NAEA@224756|Methanomicrobia	224756|Methanomicrobia	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_523013_1	1313172.YM304_01550	3.91e-17	85.5	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_294709_1	335543.Sfum_0423	0.000561	41.6	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,42TIF@68525|delta/epsilon subdivisions,2WQC4@28221|Deltaproteobacteria,2MQP8@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	CDP-alcohol phosphatidyltransferase	pgsA-2	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
k59_372914_1	1288826.MSNKSG1_17246	7.63e-63	193.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,467D0@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_99164_1	246200.SPO2013	1.34e-54	190.0	COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
k59_450712_1	669262.COK_0341	2.96e-25	98.2	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1Y8UG@135625|Pasteurellales	135625|Pasteurellales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_568355_1	864051.BurJ1DRAFT_3799	4.7e-50	174.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,2W5VT@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_686112_1	679926.Mpet_0522	5.44e-71	233.0	COG0500@1|root,arCOG01791@2157|Archaea,2XZTQ@28890|Euryarchaeota,2NAGP@224756|Methanomicrobia	224756|Methanomicrobia	Q	Methyltransferase domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
k59_372943_1	1304275.C41B8_14485	2.94e-73	227.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355	Ubie_methyltran
k59_372945_1	861299.J421_6089	2.63e-33	132.0	COG1073@1|root,COG1680@1|root,COG1073@2|Bacteria,COG1680@2|Bacteria,1ZU86@142182|Gemmatimonadetes	2|Bacteria	V	Domain of unknown function (DUF3471)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Beta-lactamase,DUF3471,Hydrolase_4
k59_881869_1	1179773.BN6_45930	3.37e-06	55.1	COG1032@1|root,COG1032@2|Bacteria,2HGPR@201174|Actinobacteria,4E2CE@85010|Pseudonocardiales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K18537,ko:K21224	ko01059,ko01130,map01059,map01130	M00831	R11389	RC03430	ko00000,ko00001,ko00002	-	-	-	B12-binding,Radical_SAM
k59_530080_1	30611.ENSOGAP00000015506	1.54e-107	319.0	KOG0118@1|root,KOG0118@2759|Eukaryota,38H08@33154|Opisthokonta,3BAHX@33208|Metazoa,3D02D@33213|Bilateria,48997@7711|Chordata,48XB7@7742|Vertebrata,3J7DM@40674|Mammalia,35J90@314146|Euarchontoglires,4MCHB@9443|Primates	33208|Metazoa	A	Heterogeneous nuclear ribonucleoprotein A B	HNRNPAB	GO:0000122,GO:0001837,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005667,GO:0005737,GO:0006355,GO:0006357,GO:0007275,GO:0008150,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0030154,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044798,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048731,GO:0048762,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0060485,GO:0065007,GO:0070013,GO:0080090,GO:0090575,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K03102,ko:K13044	ko04320,map04320	-	-	-	ko00000,ko00001,ko03019,ko03041	-	-	-	CBFNT,RRM_1
k59_530086_1	1380394.JADL01000021_gene1854	5.52e-07	51.6	COG5373@1|root,COG5373@2|Bacteria,1N7JV@1224|Proteobacteria,2TR7A@28211|Alphaproteobacteria,2JTYQ@204441|Rhodospirillales	204441|Rhodospirillales	K	Domain of unknown function (DUF4167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4167
k59_608221_1	1535422.ND16A_1350	3.56e-50	175.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,2Q61I@267889|Colwelliaceae	1236|Gammaproteobacteria	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
k59_1041721_1	1047013.AQSP01000114_gene705	4.96e-62	201.0	COG3385@1|root,COG3385@2|Bacteria,2NQNF@2323|unclassified Bacteria	2|Bacteria	L	Domain of unknown function (DUF4372)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_216925_1	706587.Desti_5376	9.41e-61	194.0	COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,42QTZ@68525|delta/epsilon subdivisions,2WMV1@28221|Deltaproteobacteria,2MQWS@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_920295_1	1453498.LG45_06475	1e-09	58.2	COG0296@1|root,COG0296@2|Bacteria,4NSTP@976|Bacteroidetes,1I4C7@117743|Flavobacteriia,2NWNY@237|Flavobacterium	976|Bacteroidetes	G	glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
k59_19593_2	109478.XP_005858492.1	1.64e-71	222.0	KOG0118@1|root,KOG0118@2759|Eukaryota,38H0V@33154|Opisthokonta,3BKR9@33208|Metazoa,3CU8X@33213|Bilateria,48B19@7711|Chordata,48V6Q@7742|Vertebrata,3JA49@40674|Mammalia,4KTXY@9397|Chiroptera	33208|Metazoa	A	Transformer-2 protein homolog	TRA2B	GO:0000003,GO:0000245,GO:0000302,GO:0000375,GO:0000377,GO:0000381,GO:0000398,GO:0001678,GO:0003002,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003729,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005737,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007275,GO:0007276,GO:0007283,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007530,GO:0008150,GO:0008152,GO:0008380,GO:0009743,GO:0009746,GO:0009749,GO:0009790,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0018993,GO:0019101,GO:0019102,GO:0019219,GO:0019222,GO:0019725,GO:0019904,GO:0019953,GO:0021537,GO:0021543,GO:0021796,GO:0021871,GO:0021978,GO:0021987,GO:0022414,GO:0022607,GO:0022613,GO:0022618,GO:0030237,GO:0030238,GO:0030900,GO:0031323,GO:0031324,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033119,GO:0033120,GO:0033500,GO:0034284,GO:0034622,GO:0034641,GO:0036002,GO:0042221,GO:0042592,GO:0042593,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043484,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045934,GO:0045935,GO:0046483,GO:0048024,GO:0048025,GO:0048026,GO:0048232,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048568,GO:0048609,GO:0048731,GO:0048856,GO:0048878,GO:0050684,GO:0050685,GO:0050686,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0051704,GO:0051716,GO:0055082,GO:0060255,GO:0060322,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070717,GO:0070887,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901700,GO:1901701,GO:1903311,GO:1903312,GO:1903313,GO:1990403,GO:1990904	-	ko:K12897	ko03040,map03040	-	-	-	ko00000,ko00001,ko01009,ko03041	-	-	-	RRM_1
k59_530165_1	27679.XP_010347558.1	2.87e-128	364.0	COG0094@1|root,KOG0397@2759|Eukaryota,38BMT@33154|Opisthokonta,3BDSE@33208|Metazoa,3CXGD@33213|Bilateria,48814@7711|Chordata,4908W@7742|Vertebrata,3J93F@40674|Mammalia,35AF0@314146|Euarchontoglires,4MC87@9443|Primates	33208|Metazoa	J	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	RPL11	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031974,GO:0031981,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070013,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02868,ko:K10523	ko03010,ko04340,ko04341,map03010,map04340,map04341	M00177,M00384	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04121	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_1003828_1	584708.Apau_2053	1.02e-64	209.0	COG0075@1|root,COG0075@2|Bacteria,3TA05@508458|Synergistetes	508458|Synergistetes	E	PFAM Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_530167_1	765912.Thimo_0060	3.03e-26	110.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1WWSQ@135613|Chromatiales	135613|Chromatiales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_530167_2	323848.Nmul_A2698	1.17e-16	78.2	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,372B3@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Transporter associated domain	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
k59_1156066_1	396588.Tgr7_0696	4.57e-61	205.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,1RPNQ@1236|Gammaproteobacteria,1WWFZ@135613|Chromatiales	135613|Chromatiales	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase
k59_845284_1	335543.Sfum_2756	9.16e-96	304.0	COG0707@1|root,COG1413@1|root,COG0707@2|Bacteria,COG1413@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2MRPC@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_419013_1	339670.Bamb_2601	1.75e-23	99.4	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,1K2FN@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_419013_2	365044.Pnap_0263	3.25e-21	91.3	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,4ADS8@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_845287_1	457570.Nther_0320	5.44e-13	64.3	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia	186801|Clostridia	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_922837_1	237368.SCABRO_00323	3.55e-30	113.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_492912_1	589865.DaAHT2_1174	1.1e-76	243.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2MHWE@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_963288_1	1502851.FG93_02729	2.42e-54	178.0	COG1173@1|root,COG1173@2|Bacteria,1MVER@1224|Proteobacteria,2TRB3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_963288_2	390874.Tpet_0419	4.06e-06	48.9	COG0444@1|root,COG0444@2|Bacteria,2GCKF@200918|Thermotogae	200918|Thermotogae	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_1007212_1	1515746.HR45_11510	3.27e-32	125.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2QDJ2@267890|Shewanellaceae	1236|Gammaproteobacteria	V	MMPL family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1007212_2	1417296.U879_01530	6.61e-11	64.3	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2VET4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_766768_1	1123257.AUFV01000012_gene2925	2.57e-62	204.0	2CIBN@1|root,2Z8JT@2|Bacteria,1R902@1224|Proteobacteria,1RXPM@1236|Gammaproteobacteria,1X5H4@135614|Xanthomonadales	135614|Xanthomonadales	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1043911_1	247633.GP2143_03044	1.7e-84	264.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1J4DZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1158729_1	1041147.AUFB01000028_gene2815	2.01e-70	232.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2TVFI@28211|Alphaproteobacteria,4B7J0@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
k59_1241366_1	2340.JV46_04180	3.54e-55	195.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1J4IX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_61061_1	864073.HFRIS_014969	5.24e-45	157.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,4726F@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
k59_728076_1	517418.Ctha_1409	9.73e-26	103.0	COG0388@1|root,COG0388@2|Bacteria,1FEVY@1090|Chlorobi	1090|Chlorobi	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_258206_1	1279019.ARQK01000058_gene671	4.42e-95	286.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1WWMZ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_534046_1	933262.AXAM01000023_gene659	6.93e-144	419.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,2MHSU@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k59_139680_1	1121422.AUMW01000025_gene355	4.23e-52	179.0	COG1042@1|root,COG1042@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_102083_1	1121405.dsmv_3110	6.74e-60	193.0	COG1484@1|root,COG1484@2|Bacteria,1MZVC@1224|Proteobacteria,430QU@68525|delta/epsilon subdivisions,2WW1K@28221|Deltaproteobacteria,2MNR3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_375736_1	870187.Thini_2177	7.89e-32	119.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,4616Y@72273|Thiotrichales	72273|Thiotrichales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
k59_375736_2	395494.Galf_0151	1.66e-16	77.8	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VKD2@28216|Betaproteobacteria,44V55@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k59_805212_1	1232437.KL662001_gene4555	5.88e-63	204.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,2MI89@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_1079799_1	1499686.BN1079_01919	2.01e-07	57.8	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2202 FOG PAS PAC domain	-	-	-	ko:K21025	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg
k59_453537_1	414684.RC1_0412	1.83e-114	349.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2JPYX@204441|Rhodospirillales	204441|Rhodospirillales	I	COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_963433_1	1248916.ANFY01000003_gene936	9.88e-06	47.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,2K8V1@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_963433_2	1535422.ND16A_0740	4.03e-83	259.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,2Q7EB@267889|Colwelliaceae	1236|Gammaproteobacteria	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_610940_1	765911.Thivi_1253	3.48e-143	430.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales	135613|Chromatiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_179515_1	358823.DF19_11400	5.12e-15	79.7	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
k59_1079834_1	1089552.KI911559_gene1161	2.92e-15	74.7	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2U0W2@28211|Alphaproteobacteria,2JSK7@204441|Rhodospirillales	204441|Rhodospirillales	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
k59_1079834_2	1205753.A989_17308	8.6e-53	174.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1X38I@135614|Xanthomonadales	135614|Xanthomonadales	V	Transport permease protein	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k59_220713_1	1121405.dsmv_0177	7.47e-43	145.0	COG0589@1|root,COG0589@2|Bacteria,1N5SY@1224|Proteobacteria,42UUI@68525|delta/epsilon subdivisions,2WQFX@28221|Deltaproteobacteria,2MM5G@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_419214_1	61853.ENSNLEP00000010736	1.43e-129	368.0	COG0693@1|root,KOG2764@2759|Eukaryota,3A1YC@33154|Opisthokonta,3BQJG@33208|Metazoa,3CY3Z@33213|Bilateria,482Y6@7711|Chordata,493SJ@7742|Vertebrata,3J457@40674|Mammalia,35BTW@314146|Euarchontoglires,4MB35@9443|Primates	33208|Metazoa	V	Parkinsonism associated deglycase	PARK7	GO:0000003,GO:0000302,GO:0000785,GO:0001504,GO:0001505,GO:0001817,GO:0001819,GO:0001932,GO:0001933,GO:0001934,GO:0001963,GO:0002020,GO:0002082,GO:0002237,GO:0002673,GO:0002675,GO:0002682,GO:0002684,GO:0002790,GO:0002861,GO:0002863,GO:0002864,GO:0002866,GO:0003674,GO:0003676,GO:0003712,GO:0003713,GO:0003723,GO:0003729,GO:0003824,GO:0005102,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005759,GO:0005783,GO:0005829,GO:0006066,GO:0006081,GO:0006082,GO:0006089,GO:0006091,GO:0006119,GO:0006139,GO:0006140,GO:0006163,GO:0006259,GO:0006281,GO:0006355,GO:0006357,GO:0006464,GO:0006469,GO:0006508,GO:0006517,GO:0006518,GO:0006521,GO:0006575,GO:0006584,GO:0006725,GO:0006749,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006950,GO:0006974,GO:0006979,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007264,GO:0007265,GO:0007267,GO:0007268,GO:0007276,GO:0007283,GO:0007565,GO:0007568,GO:0007610,GO:0007626,GO:0008047,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008283,GO:0008344,GO:0009058,GO:0009100,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009306,GO:0009438,GO:0009441,GO:0009566,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009712,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009896,GO:0009914,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010155,GO:0010273,GO:0010310,GO:0010466,GO:0010468,GO:0010469,GO:0010506,GO:0010508,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0010646,GO:0010647,GO:0010648,GO:0010817,GO:0010821,GO:0010822,GO:0010941,GO:0010942,GO:0010951,GO:0012505,GO:0014065,GO:0015031,GO:0015696,GO:0015833,GO:0015844,GO:0015850,GO:0015872,GO:0015893,GO:0015980,GO:0016020,GO:0016043,GO:0016053,GO:0016209,GO:0016310,GO:0016491,GO:0016530,GO:0016531,GO:0016532,GO:0016604,GO:0016605,GO:0016684,GO:0016787,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0018158,GO:0018171,GO:0018193,GO:0018195,GO:0018198,GO:0018205,GO:0018307,GO:0018323,GO:0018958,GO:0019219,GO:0019220,GO:0019222,GO:0019249,GO:0019538,GO:0019637,GO:0019693,GO:0019725,GO:0019752,GO:0019899,GO:0019900,GO:0019953,GO:0019955,GO:0022414,GO:0022898,GO:0022900,GO:0022904,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0023061,GO:0030072,GO:0030073,GO:0030091,GO:0030162,GO:0030234,GO:0030424,GO:0030534,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031331,GO:0031333,GO:0031347,GO:0031349,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031647,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031981,GO:0031982,GO:0032091,GO:0032092,GO:0032101,GO:0032103,GO:0032147,GO:0032148,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032409,GO:0032410,GO:0032411,GO:0032412,GO:0032413,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032677,GO:0032757,GO:0032768,GO:0032770,GO:0032787,GO:0032879,GO:0032880,GO:0032940,GO:0033036,GO:0033043,GO:0033135,GO:0033138,GO:0033143,GO:0033145,GO:0033157,GO:0033233,GO:0033234,GO:0033238,GO:0033240,GO:0033365,GO:0033500,GO:0033554,GO:0033673,GO:0033674,GO:0033860,GO:0033864,GO:0033993,GO:0034308,GO:0034309,GO:0034504,GO:0034599,GO:0034613,GO:0034614,GO:0034641,GO:0034762,GO:0034763,GO:0034764,GO:0034765,GO:0034766,GO:0034767,GO:0035257,GO:0035258,GO:0035556,GO:0035690,GO:0036211,GO:0036470,GO:0036471,GO:0036478,GO:0036524,GO:0036525,GO:0036526,GO:0036527,GO:0036528,GO:0036529,GO:0036530,GO:0036531,GO:0040008,GO:0042053,GO:0042069,GO:0042176,GO:0042177,GO:0042180,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042391,GO:0042417,GO:0042493,GO:0042542,GO:0042592,GO:0042593,GO:0042743,GO:0042773,GO:0042775,GO:0042802,GO:0042803,GO:0042886,GO:0042981,GO:0042995,GO:0043005,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043154,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043230,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043269,GO:0043270,GO:0043271,GO:0043281,GO:0043388,GO:0043393,GO:0043412,GO:0043436,GO:0043457,GO:0043467,GO:0043496,GO:0043523,GO:0043524,GO:0043549,GO:0043603,GO:0043900,GO:0043902,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044297,GO:0044388,GO:0044390,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044427,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0044703,GO:0044706,GO:0045121,GO:0045184,GO:0045185,GO:0045333,GO:0045340,GO:0045764,GO:0045859,GO:0045860,GO:0045861,GO:0045893,GO:0045915,GO:0045926,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0045964,GO:0045981,GO:0046034,GO:0046165,GO:0046295,GO:0046394,GO:0046483,GO:0046677,GO:0046688,GO:0046689,GO:0046822,GO:0046823,GO:0046825,GO:0046826,GO:0046872,GO:0046879,GO:0046903,GO:0046914,GO:0046983,GO:0048015,GO:0048017,GO:0048232,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048609,GO:0048638,GO:0048640,GO:0048878,GO:0050681,GO:0050727,GO:0050729,GO:0050776,GO:0050778,GO:0050787,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050821,GO:0050896,GO:0051049,GO:0051050,GO:0051051,GO:0051090,GO:0051091,GO:0051093,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051186,GO:0051193,GO:0051223,GO:0051224,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051336,GO:0051338,GO:0051339,GO:0051340,GO:0051341,GO:0051346,GO:0051347,GO:0051348,GO:0051349,GO:0051352,GO:0051353,GO:0051427,GO:0051438,GO:0051444,GO:0051457,GO:0051583,GO:0051595,GO:0051641,GO:0051649,GO:0051651,GO:0051704,GO:0051707,GO:0051716,GO:0051881,GO:0051896,GO:0051897,GO:0051899,GO:0051920,GO:0051934,GO:0051937,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060081,GO:0060135,GO:0060249,GO:0060255,GO:0060341,GO:0060548,GO:0060765,GO:0061136,GO:0061687,GO:0061827,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070050,GO:0070062,GO:0070201,GO:0070301,GO:0070491,GO:0070727,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071236,GO:0071310,GO:0071396,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072330,GO:0072521,GO:0072593,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0080154,GO:0090073,GO:0090085,GO:0090086,GO:0090087,GO:0090304,GO:0090317,GO:0090322,GO:0090493,GO:0090494,GO:0097110,GO:0097159,GO:0097164,GO:0097223,GO:0097237,GO:0097238,GO:0097458,GO:0097501,GO:0098589,GO:0098657,GO:0098754,GO:0098772,GO:0098805,GO:0098810,GO:0098857,GO:0098869,GO:0098916,GO:0099536,GO:0099537,GO:0099601,GO:0106044,GO:0106045,GO:0106046,GO:0110095,GO:0110096,GO:0120025,GO:0140041,GO:0140096,GO:0140104,GO:0140110,GO:1900180,GO:1900182,GO:1900407,GO:1900408,GO:1900409,GO:1900449,GO:1900450,GO:1900542,GO:1900544,GO:1901031,GO:1901032,GO:1901033,GO:1901135,GO:1901214,GO:1901215,GO:1901298,GO:1901299,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901615,GO:1901617,GO:1901654,GO:1901655,GO:1901668,GO:1901671,GO:1901700,GO:1901701,GO:1901799,GO:1901857,GO:1901983,GO:1901984,GO:1902041,GO:1902042,GO:1902175,GO:1902176,GO:1902177,GO:1902235,GO:1902236,GO:1902531,GO:1902532,GO:1902533,GO:1902680,GO:1902882,GO:1902883,GO:1902884,GO:1902903,GO:1902956,GO:1902958,GO:1903050,GO:1903051,GO:1903072,GO:1903073,GO:1903093,GO:1903094,GO:1903121,GO:1903122,GO:1903135,GO:1903136,GO:1903146,GO:1903167,GO:1903168,GO:1903176,GO:1903178,GO:1903179,GO:1903181,GO:1903189,GO:1903195,GO:1903197,GO:1903198,GO:1903200,GO:1903201,GO:1903202,GO:1903203,GO:1903204,GO:1903205,GO:1903206,GO:1903207,GO:1903208,GO:1903209,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903376,GO:1903377,GO:1903383,GO:1903384,GO:1903426,GO:1903427,GO:1903428,GO:1903506,GO:1903508,GO:1903561,GO:1903573,GO:1903578,GO:1903580,GO:1903599,GO:1903750,GO:1903751,GO:1903827,GO:1903828,GO:1903829,GO:1903862,GO:1904062,GO:1904063,GO:1904064,GO:1904782,GO:1904833,GO:1904950,GO:1905258,GO:1905259,GO:1905446,GO:1905448,GO:1905516,GO:1905897,GO:1990169,GO:1990381,GO:1990748,GO:2000058,GO:2000059,GO:2000112,GO:2000116,GO:2000117,GO:2000121,GO:2000152,GO:2000157,GO:2000241,GO:2000243,GO:2000272,GO:2000273,GO:2000275,GO:2000277,GO:2000282,GO:2000284,GO:2000310,GO:2000377,GO:2000378,GO:2000379,GO:2000677,GO:2000679,GO:2000823,GO:2000825,GO:2001023,GO:2001024,GO:2001038,GO:2001039,GO:2001141,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001237,GO:2001242,GO:2001243,GO:2001244,GO:2001257,GO:2001258,GO:2001267,GO:2001268	3.5.1.124	ko:K05687	ko05012,map05012	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	DJ-1_PfpI
k59_1198386_2	543913.D521_0886	6.6e-33	122.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VHWQ@28216|Betaproteobacteria,1KQQF@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k59_22307_1	644968.DFW101_3359	3.09e-27	109.0	2F9C1@1|root,341NY@2|Bacteria,1NXYC@1224|Proteobacteria,430UA@68525|delta/epsilon subdivisions,2WW49@28221|Deltaproteobacteria,2M8XW@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_493094_1	1122139.KB907863_gene1871	1.45e-40	151.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1XHG0@135619|Oceanospirillales	135619|Oceanospirillales	M	COG0729 Outer membrane protein	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
k59_419248_1	225849.swp_1934	8.56e-86	264.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,1RNN9@1236|Gammaproteobacteria,2QA72@267890|Shewanellaceae	1236|Gammaproteobacteria	OU	PFAM peptidase S49	sohB	GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0016020,GO:0019538,GO:0043170,GO:0044238,GO:0044464,GO:0071704,GO:0071944,GO:1901564	-	ko:K04774	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49,Peptidase_S49_N
k59_102182_1	1232410.KI421418_gene2422	1.02e-85	265.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria,43VZ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	SelR domain	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
k59_649100_2	395492.Rleg2_1002	5.23e-23	97.1	COG3293@1|root,COG3293@2|Bacteria,1REX3@1224|Proteobacteria,2U89Y@28211|Alphaproteobacteria,4BM8S@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_963485_2	123214.PERMA_0792	5.63e-21	92.8	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K16079,ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2,1.B.4.2.1	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2
k59_571208_1	9606.ENSP00000290299	4.82e-138	392.0	COG0712@1|root,KOG1662@2759|Eukaryota,39SAW@33154|Opisthokonta,3BEPI@33208|Metazoa,3CTSY@33213|Bilateria,48466@7711|Chordata,48ZBF@7742|Vertebrata,3J48W@40674|Mammalia,35G2U@314146|Euarchontoglires,4MD3C@9443|Primates,4N26F@9604|Hominidae	33208|Metazoa	C	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a ATP6 static relative to the rotary elements	ATP5O	GO:0000275,GO:0000276,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0005756,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006839,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0007275,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008289,GO:0008340,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0010259,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016043,GO:0016310,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0022857,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0033177,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042407,GO:0042776,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044877,GO:0045259,GO:0045261,GO:0045263,GO:0045269,GO:0046034,GO:0046390,GO:0046483,GO:0046907,GO:0048856,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0055086,GO:0061024,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600,GO:1990542	-	ko:K02137	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	OSCP
k59_220753_1	176299.Atu5478	1.48e-09	66.6	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,2UJ7M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
k59_139775_1	224911.27354319	8.48e-121	375.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSN5@28211|Alphaproteobacteria,3JUXZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	MA20_43170	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_336261_1	1122179.KB890450_gene4580	1.43e-79	259.0	COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,1ISP6@117747|Sphingobacteriia	976|Bacteroidetes	S	COG2366 Protein related to penicillin acylase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
k59_179568_2	469383.Cwoe_3509	6.64e-27	107.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CPEE@84995|Rubrobacteria	84995|Rubrobacteria	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
k59_220770_2	1123401.JHYQ01000008_gene419	1.79e-69	218.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,4609Y@72273|Thiotrichales	72273|Thiotrichales	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_689065_2	1122211.JMLW01000002_gene1864	2.36e-64	204.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1RU35@1236|Gammaproteobacteria,1XID0@135619|Oceanospirillales	135619|Oceanospirillales	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	degU	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_139787_1	1121396.KB893062_gene2776	2.85e-87	272.0	COG4650@1|root,COG4650@2|Bacteria,1MX6U@1224|Proteobacteria,42NHB@68525|delta/epsilon subdivisions,2WKUB@28221|Deltaproteobacteria,2MMWE@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Regulator of RNA terminal phosphate cyclase	rtcR	-	-	ko:K14414	-	-	-	-	ko00000,ko03000	-	-	-	RtcR,Sigma54_activat
k59_963516_1	1286106.MPL1_00922	2.62e-59	206.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,45ZN3@72273|Thiotrichales	72273|Thiotrichales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1044078_1	864702.OsccyDRAFT_3980	1.52e-18	79.0	COG3369@1|root,COG3369@2|Bacteria,1G7ZE@1117|Cyanobacteria,1HCSP@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
k59_493133_1	391600.ABRU01000047_gene2339	1.92e-45	160.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,2KFPW@204458|Caulobacterales	204458|Caulobacterales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_258378_1	742738.HMPREF9460_04007	2.78e-09	59.3	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,267JG@186813|unclassified Clostridiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_258378_2	2340.JV46_14270	4.96e-11	63.9	COG1394@1|root,COG1394@2|Bacteria,1RJ1P@1224|Proteobacteria,1S75D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP synthase subunit D	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
k59_297776_1	866775.HMPREF9243_1994	2.85e-36	133.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,27DP0@186827|Aerococcaceae	91061|Bacilli	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_963545_2	1121033.AUCF01000042_gene2668	0.000355	43.5	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2TUX0@28211|Alphaproteobacteria,2JRSA@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
k59_443729_2	1121015.N789_08605	3.29e-20	90.9	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1X4P8@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_326073_2	765910.MARPU_14225	9.05e-67	213.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1WWYB@135613|Chromatiales	135613|Chromatiales	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_1148899_1	177437.HRM2_26710	6.57e-46	157.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,42MGJ@68525|delta/epsilon subdivisions,2WJ5E@28221|Deltaproteobacteria,2MHXN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_835455_1	768671.ThimaDRAFT_4023	6.43e-44	162.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales	135613|Chromatiales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_287095_1	1247963.JPHU01000006_gene132	2.48e-39	150.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TSXA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	OU	Signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_1148908_2	1121403.AUCV01000001_gene902	5.65e-06	49.3	COG0741@1|root,COG0741@2|Bacteria,1MWKE@1224|Proteobacteria,42QM3@68525|delta/epsilon subdivisions,2WKI2@28221|Deltaproteobacteria,2MI4S@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_91929_1	338966.Ppro_3708	2.48e-61	199.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_600791_1	868131.MSWAN_1828	2.63e-24	98.6	COG1371@1|root,arCOG04055@2157|Archaea,2XXRX@28890|Euryarchaeota,23P74@183925|Methanobacteria	183925|Methanobacteria	S	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently	-	-	-	-	-	-	-	-	-	-	-	-	Archease
k59_405817_1	635013.TherJR_1142	6.41e-49	169.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,26072@186807|Peptococcaceae	186801|Clostridia	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_795988_1	472759.Nhal_2659	2.49e-104	312.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,1RQ15@1236|Gammaproteobacteria,1X0JQ@135613|Chromatiales	135613|Chromatiales	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1109941_1	435908.IDSA_05895	3.43e-85	271.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,2QFUW@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_718552_1	196367.JNFG01000058_gene555	2.17e-12	65.9	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2VSCN@28216|Betaproteobacteria,1K73W@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
k59_12681_1	1122132.AQYH01000005_gene637	5.78e-43	160.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,4B7MU@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	penicillin-binding protein	pbpC	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_208567_2	56780.SYN_01264	1.7e-61	193.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,42SCT@68525|delta/epsilon subdivisions,2WPA7@28221|Deltaproteobacteria,2MQJI@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_208575_1	61853.ENSNLEP00000017652	4.52e-83	272.0	COG0656@1|root,KOG4563@1|root,KOG1577@2759|Eukaryota,KOG4563@2759|Eukaryota,39SU9@33154|Opisthokonta,3BCZB@33208|Metazoa,3CX4Z@33213|Bilateria,487ZZ@7711|Chordata,494J9@7742|Vertebrata,3J3KE@40674|Mammalia,35NCT@314146|Euarchontoglires,4M9RX@9443|Primates	33208|Metazoa	BD	Nuclear autoantigenic sperm protein	NASP	GO:0000003,GO:0000082,GO:0000228,GO:0000278,GO:0000785,GO:0000790,GO:0001701,GO:0001824,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006335,GO:0006336,GO:0006338,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007275,GO:0007548,GO:0008150,GO:0008152,GO:0008283,GO:0008406,GO:0008584,GO:0009058,GO:0009059,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009987,GO:0010033,GO:0014070,GO:0016043,GO:0022402,GO:0022414,GO:0022607,GO:0031497,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0033574,GO:0033993,GO:0034622,GO:0034641,GO:0034645,GO:0034723,GO:0034724,GO:0034728,GO:0042221,GO:0042393,GO:0043009,GO:0043044,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043486,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0044877,GO:0045137,GO:0046483,GO:0046546,GO:0046661,GO:0048513,GO:0048608,GO:0048731,GO:0048856,GO:0050896,GO:0051276,GO:0061458,GO:0065003,GO:0065004,GO:0070013,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:1901360,GO:1901576,GO:1901654,GO:1901700,GO:1903047	-	ko:K11291	-	-	-	-	ko00000,ko03036	-	-	-	SHNi-TPR,TPR_12,TPR_8
k59_1188422_1	767817.Desgi_1689	3.62e-89	286.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,247JV@186801|Clostridia,2605J@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5,1.8.5.6	ko:K08352,ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R10149,R11487	RC00168,RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_718567_1	56780.SYN_02160	9.91e-66	213.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2MQ57@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_248105_1	1123517.JOMR01000001_gene1183	9.78e-45	164.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,462HB@72273|Thiotrichales	72273|Thiotrichales	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_1033757_1	482537.XP_008575060.1	8.75e-118	341.0	KOG0836@1|root,KOG0836@2759|Eukaryota,38BVH@33154|Opisthokonta,3BA65@33208|Metazoa,3CRQI@33213|Bilateria,482R7@7711|Chordata,48YHQ@7742|Vertebrata,3J4WB@40674|Mammalia,35HPC@314146|Euarchontoglires	33208|Metazoa	Z	barbed-end actin filament capping	CAPZA1	GO:0000003,GO:0000902,GO:0001709,GO:0001932,GO:0001933,GO:0002376,GO:0002478,GO:0002495,GO:0002504,GO:0003006,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005869,GO:0005875,GO:0005886,GO:0005903,GO:0005911,GO:0005938,GO:0006810,GO:0006888,GO:0006928,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007018,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007293,GO:0007294,GO:0007444,GO:0007596,GO:0007599,GO:0008064,GO:0008092,GO:0008150,GO:0008290,GO:0009611,GO:0009653,GO:0009888,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009994,GO:0010033,GO:0010563,GO:0010591,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0015629,GO:0015630,GO:0016020,GO:0016043,GO:0016192,GO:0016324,GO:0019220,GO:0019221,GO:0019222,GO:0019882,GO:0019884,GO:0019886,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030029,GO:0030036,GO:0030054,GO:0030154,GO:0030706,GO:0030716,GO:0030832,GO:0030833,GO:0030834,GO:0030835,GO:0030837,GO:0030863,GO:0031323,GO:0031324,GO:0031333,GO:0031344,GO:0031345,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0032271,GO:0032272,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032872,GO:0032873,GO:0032956,GO:0032970,GO:0032989,GO:0032991,GO:0033043,GO:0034097,GO:0034329,GO:0034330,GO:0035220,GO:0035295,GO:0035722,GO:0042060,GO:0042221,GO:0042325,GO:0042326,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043242,GO:0043244,GO:0043254,GO:0043408,GO:0043409,GO:0043933,GO:0044085,GO:0044087,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044459,GO:0044464,GO:0044703,GO:0045087,GO:0045165,GO:0045177,GO:0045936,GO:0046328,GO:0046329,GO:0046907,GO:0046982,GO:0046983,GO:0048002,GO:0048193,GO:0048468,GO:0048477,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048609,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050817,GO:0050878,GO:0050896,GO:0051016,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051489,GO:0051490,GO:0051493,GO:0051494,GO:0051641,GO:0051649,GO:0051693,GO:0051704,GO:0051716,GO:0060255,GO:0060429,GO:0060491,GO:0065003,GO:0065007,GO:0065008,GO:0070302,GO:0070303,GO:0070671,GO:0070887,GO:0071203,GO:0071310,GO:0071345,GO:0071349,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0097435,GO:0098590,GO:0098862,GO:0099568,GO:0110053,GO:0120032,GO:0120033,GO:0120035,GO:1901879,GO:1901880,GO:1902531,GO:1902532,GO:1902743,GO:1902903,GO:1902904	-	ko:K10364	ko04144,map04144	-	-	-	ko00000,ko00001,ko04131,ko04147,ko04812	-	-	-	F-actin_cap_A
k59_12697_1	1134912.AJTV01000023_gene2878	1.08e-78	254.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,36Y6U@31993|Methylocystaceae	28211|Alphaproteobacteria	MU	Outer membrane efflux protein	oprN	-	-	ko:K18300,ko:K19593	-	M00641,M00769	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17,2.A.6.2.34	-	-	OEP
k59_561308_1	314285.KT71_01615	2.85e-62	205.0	COG0671@1|root,COG0671@2|Bacteria,1PX74@1224|Proteobacteria,1SM7V@1236|Gammaproteobacteria,1J8CN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
k59_1229241_1	1304885.AUEY01000022_gene3395	1.19e-93	284.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MHXJ@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_874641_1	565045.NOR51B_675	2.24e-65	217.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_1070386_1	709986.Deima_0872	1.58e-43	157.0	COG3325@1|root,COG3325@2|Bacteria	2|Bacteria	G	chitin binding	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_4_9,CBM_5_12,Glyco_hydro_18,fn3
k59_248135_1	439235.Dalk_1318	5.17e-68	209.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,43BHF@68525|delta/epsilon subdivisions,2WQUJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_1110008_1	1207063.P24_13163	3.31e-78	248.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,2JR2A@204441|Rhodospirillales	204441|Rhodospirillales	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
k59_953190_1	1042377.AFPJ01000043_gene834	1.18e-87	278.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RSG9@1236|Gammaproteobacteria,464W2@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	aminopeptidase	pepN	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
k59_678927_1	1267005.KB911263_gene1378	3.29e-53	187.0	28H8H@1|root,2Z7KE@2|Bacteria,1MV77@1224|Proteobacteria,2TSVV@28211|Alphaproteobacteria,3N7SW@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4159)	MA20_44655	-	-	-	-	-	-	-	-	-	-	-	BatA,DUF4159
k59_678927_2	1267005.KB911263_gene1377	1.03e-69	222.0	COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,2TTDX@28211|Alphaproteobacteria,3N7PV@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function DUF58	MA20_44650	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_522598_1	1167006.UWK_01420	9.88e-69	226.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_169524_1	1504672.669785405	4.87e-84	262.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,4AB30@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
k59_678939_1	1122135.KB893171_gene2152	2.11e-66	224.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1QU7N@1224|Proteobacteria,2TXA8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase central domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k59_169539_1	278963.ATWD01000001_gene3376	7.17e-20	85.1	COG5405@1|root,COG5405@2|Bacteria,3Y42U@57723|Acidobacteria,2JIR7@204432|Acidobacteriia	204432|Acidobacteriia	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
k59_169539_2	671143.DAMO_0070	7.62e-37	134.0	COG4974@1|root,COG4974@2|Bacteria,2NP4H@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase, N-terminal SAM-like domain	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_130390_1	1121413.JMKT01000017_gene361	4.2e-65	209.0	COG3842@1|root,COG3842@2|Bacteria,1QWPH@1224|Proteobacteria,43E0E@68525|delta/epsilon subdivisions,2X75F@28221|Deltaproteobacteria,2MHCG@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM ABC transporter related	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
k59_1033848_1	305700.B447_06337	7.63e-133	381.0	COG0265@1|root,COG0265@2|Bacteria,1R40X@1224|Proteobacteria,2VMJD@28216|Betaproteobacteria,2KVZ7@206389|Rhodocyclales	206389|Rhodocyclales	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
k59_718640_1	566466.NOR53_1390	2.71e-102	310.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1J7ES@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	MFS/sugar transport protein	ynaJ	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
k59_326198_1	1232437.KL662043_gene2213	1.64e-55	195.0	COG0591@1|root,COG5002@1|root,COG0591@2|Bacteria,COG5002@2|Bacteria,1QTSW@1224|Proteobacteria,43CHB@68525|delta/epsilon subdivisions,2X7SG@28221|Deltaproteobacteria,2MJ3Z@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,SSF,SpoIIE
k59_874699_1	880072.Desac_2720	5.52e-19	84.7	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2MQF7@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k59_874699_2	272630.MexAM1_META1p0836	4.57e-17	82.4	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,1JQVQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_522645_1	1121456.ATVA01000013_gene860	5.28e-98	303.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2WJMB@28221|Deltaproteobacteria,2M9H9@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM Carboxylyase-related protein	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k59_600918_1	1121878.AUGL01000002_gene2295	9.02e-29	114.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,1RQKM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_639761_1	396588.Tgr7_3074	3.03e-52	171.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
k59_483121_1	335543.Sfum_1817	1.01e-100	310.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MRH3@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,RIO1
k59_835594_1	195253.Syn6312_2608	1.25e-35	138.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1G17N@1117|Cyanobacteria,1H3W5@1129|Synechococcus	1117|Cyanobacteria	T	transmembrane sensor domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_365966_1	1040982.AXAL01000029_gene4285	7.45e-110	329.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2TSQA@28211|Alphaproteobacteria,43KUU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
k59_405994_1	107636.JQNK01000009_gene3513	1.11e-238	670.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2TRXG@28211|Alphaproteobacteria,370BU@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_561397_1	335543.Sfum_2531	9.1e-58	192.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,2MRAV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
k59_522673_1	523791.Kkor_1853	2.53e-67	215.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1XIBE@135619|Oceanospirillales	135619|Oceanospirillales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_208721_1	82995.CR62_10005	5.34e-05	50.1	COG0454@1|root,COG0454@2|Bacteria,1QVMZ@1224|Proteobacteria,1T2F9@1236|Gammaproteobacteria,405QY@613|Serratia	1236|Gammaproteobacteria	K	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_51922_1	555779.Dthio_PD1478	5.63e-65	210.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions,2WR9X@28221|Deltaproteobacteria,2MAU1@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_522683_1	1129794.C427_0214	2.3e-92	285.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,1T20X@1236|Gammaproteobacteria,464H1@72275|Alteromonadaceae	1236|Gammaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
k59_130456_1	1280952.HJA_16939	1.04e-42	154.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,43X2S@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	pyridine nucleotide-disulfide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
k59_757209_1	384765.SIAM614_22462	2.46e-97	293.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria	1224|Proteobacteria	L	Transposase	ISPlu13C	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1033951_1	391616.OA238_c48310	9.4e-110	326.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TTBD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_406056_1	1121007.AUML01000033_gene2841	1.32e-15	82.0	COG1361@1|root,COG1470@1|root,COG3291@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria,COG3291@2|Bacteria,4NTQU@976|Bacteroidetes,1I49M@117743|Flavobacteriia,2YIQ9@290174|Aquimarina	976|Bacteroidetes	M	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
k59_1149112_1	927677.ALVU02000001_gene3775	1.9e-26	99.4	COG3514@1|root,COG3514@2|Bacteria,1G9IY@1117|Cyanobacteria	1117|Cyanobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
k59_913619_1	1117647.M5M_13630	1.49e-70	231.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1J4CS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_12881_1	879212.DespoDRAFT_00688	1.61e-96	306.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
k59_994547_1	1037409.BJ6T_37170	9.77e-06	46.2	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,2U5PV@28211|Alphaproteobacteria,3K0M9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Cytidylyltransferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
k59_994547_2	794846.AJQU01000035_gene3967	1.21e-52	175.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_406094_1	391038.Bphy_3172	9.8e-23	97.8	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,1K0CE@119060|Burkholderiaceae	28216|Betaproteobacteria	C	alcohol dehydrogenase	-	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_994556_1	641491.DND132_2625	2.63e-76	239.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,42NEN@68525|delta/epsilon subdivisions,2WK9G@28221|Deltaproteobacteria,2MAGX@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1034004_1	981327.F925_00514	8.28e-14	68.6	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,3NKDT@468|Moraxellaceae	1236|Gammaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
k59_1034004_2	1218352.B597_005020	7.22e-51	170.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1Z06K@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048	Formyl_trans_C,Formyl_trans_N
k59_1229474_2	1384054.N790_03180	1.62e-18	89.0	COG0154@1|root,COG3391@1|root,COG0154@2|Bacteria,COG3391@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1X4K6@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia	gatAX	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase,Lipocalin_5
k59_796196_1	313596.RB2501_09320	1.83e-10	65.1	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PKD,Sortilin-Vps10,TSP_3
k59_130512_1	247634.GPB2148_14	4.1e-119	350.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	2.7.7.49	ko:K00986,ko:K07497	-	-	-	-	ko00000,ko01000	-	-	-	HTH_32,rve,rve_3
k59_1188640_1	398512.JQKC01000008_gene967	4.47e-41	144.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,3WJZ2@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_169684_1	56780.SYN_01405	7.66e-65	221.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_287408_1	9544.ENSMMUP00000041113	1.41e-82	248.0	KOG3504@1|root,KOG3504@2759|Eukaryota,3A882@33154|Opisthokonta,3BUET@33208|Metazoa,3DAWM@33213|Bilateria,48ECI@7711|Chordata,49AWK@7742|Vertebrata,3JGJW@40674|Mammalia,35PS7@314146|Euarchontoglires,4MGPE@9443|Primates,366R1@314294|Cercopithecoidea	33208|Metazoa	J	60S ribosomal protein	RPL29	GO:0000003,GO:0000184,GO:0000956,GO:0002181,GO:0003674,GO:0003682,GO:0003735,GO:0005198,GO:0005488,GO:0005539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005791,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007155,GO:0007275,GO:0007565,GO:0007566,GO:0007568,GO:0008104,GO:0008150,GO:0008152,GO:0008201,GO:0008283,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0012505,GO:0015031,GO:0015833,GO:0015934,GO:0016020,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0019898,GO:0022414,GO:0022610,GO:0022625,GO:0022626,GO:0030867,GO:0031090,GO:0031589,GO:0031984,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0035264,GO:0040007,GO:0042175,GO:0042788,GO:0042886,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0048589,GO:0048856,GO:0050789,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0060255,GO:0065007,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097367,GO:0098552,GO:0098554,GO:0098556,GO:0098562,GO:0098588,GO:0098827,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901681,GO:1990904	-	ko:K02905	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29e
k59_1034040_1	1122164.JHWF01000012_gene2595	3.93e-73	232.0	COG0520@1|root,COG0520@2|Bacteria,1MX5B@1224|Proteobacteria,1S43P@1236|Gammaproteobacteria,1JE4E@118969|Legionellales	118969|Legionellales	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_994605_1	1232437.KL662008_gene3440	6.14e-25	98.6	COG1913@1|root,COG1913@2|Bacteria,1NCS0@1224|Proteobacteria,42WBW@68525|delta/epsilon subdivisions,2WR84@28221|Deltaproteobacteria,2MNUK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
k59_252004_2	1121370.AQUY01000002_gene2026	0.000651	43.5	COG0847@1|root,COG0847@2|Bacteria,2IKNT@201174|Actinobacteria,22MYS@1653|Corynebacteriaceae	201174|Actinobacteria	L	DNA polymerase III	dnaQ2	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
k59_369730_1	1380390.JIAT01000011_gene2520	3.96e-13	73.2	COG0637@1|root,COG0637@2|Bacteria,2I2IT@201174|Actinobacteria,4CQSD@84995|Rubrobacteria	84995|Rubrobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
k59_369736_1	1545915.JROG01000001_gene157	1.11e-42	155.0	COG1680@1|root,COG1680@2|Bacteria,1R8N7@1224|Proteobacteria,2UCNR@28211|Alphaproteobacteria,2K0VY@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_626570_1	1266908.AQPB01000058_gene2330	1.17e-12	71.6	COG3103@1|root,COG4991@2|Bacteria,1MX7M@1224|Proteobacteria,1RS74@1236|Gammaproteobacteria,1WY3A@135613|Chromatiales	135613|Chromatiales	T	SH3 domain	-	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
k59_154744_1	398580.Dshi_2656	6.63e-84	268.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,2VFZH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,HTH_24,PUA_2
k59_312806_1	648757.Rvan_2843	9.68e-59	187.0	COG0582@1|root,COG0582@2|Bacteria,1P1R9@1224|Proteobacteria,2U190@28211|Alphaproteobacteria,3N6S5@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_193649_1	1521187.JPIM01000028_gene1620	4.75e-70	236.0	COG1404@1|root,COG1404@2|Bacteria,2G5S0@200795|Chloroflexi,376YT@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
k59_820328_1	314275.MADE_1009710	6.57e-50	171.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,465PG@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
k59_820328_2	283942.IL1261	0.000297	42.7	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,2QFRW@267893|Idiomarinaceae	1236|Gammaproteobacteria	K	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_820331_1	335543.Sfum_0828	8.84e-67	228.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKB1@28221|Deltaproteobacteria,2MR2G@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_274086_1	10116.ENSRNOP00000065391	2.12e-90	295.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39RKB@33154|Opisthokonta,3BK61@33208|Metazoa,3E43G@33213|Bilateria,48JXY@7711|Chordata,49GK2@7742|Vertebrata,3JJ5B@40674|Mammalia,35U9R@314146|Euarchontoglires	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1725,Exo_endo_phos,Exo_endo_phos_2,RVT_1
k59_508594_2	350054.Mflv_0436	9.37e-16	80.9	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,232VN@1762|Mycobacteriaceae	201174|Actinobacteria	I	esterase	lipO	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
k59_1214264_1	335543.Sfum_1212	4.04e-115	346.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2MQXV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_312900_1	1429916.X566_16590	6.68e-77	250.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2TTXG@28211|Alphaproteobacteria,3JVJZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
k59_274144_1	1123372.AUIT01000012_gene1680	7.84e-05	43.9	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2GGXQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_274144_2	94122.Shewana3_2341	5.32e-71	236.0	COG0243@1|root,COG0243@2|Bacteria,1R5ZE@1224|Proteobacteria,1S1Y2@1236|Gammaproteobacteria,2QB5X@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_508613_1	1033802.SSPSH_000452	3.01e-64	207.0	COG0300@1|root,COG0300@2|Bacteria,1QU6Z@1224|Proteobacteria,1T1P9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1174949_2	326297.Sama_0227	1.2e-28	105.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,2QBN5@267890|Shewanellaceae	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_508627_1	396588.Tgr7_2123	3.01e-97	301.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales	135613|Chromatiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_154894_1	1366046.HIMB11_02149	6.86e-82	252.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2TQVW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
k59_468993_1	349521.HCH_04588	2.27e-75	233.0	2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1XIR7@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF2797)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2797
k59_820430_1	61622.XP_010353625.1	8.59e-183	525.0	KOG2447@1|root,KOG2447@2759|Eukaryota,38C03@33154|Opisthokonta,3BAZG@33208|Metazoa,3CU2K@33213|Bilateria,4811D@7711|Chordata,49481@7742|Vertebrata,3J4SG@40674|Mammalia,35CMJ@314146|Euarchontoglires,4MA03@9443|Primates,362G6@314294|Cercopithecoidea	33208|Metazoa	O	Ribophorin II	RPN2	GO:0000421,GO:0002252,GO:0002376,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005776,GO:0005783,GO:0005789,GO:0005791,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0006996,GO:0007029,GO:0007568,GO:0008150,GO:0008152,GO:0008250,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010256,GO:0012505,GO:0016020,GO:0016043,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0031090,GO:0031984,GO:0032502,GO:0032991,GO:0034645,GO:0035010,GO:0036211,GO:0042175,GO:0042221,GO:0042493,GO:0043021,GO:0043022,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051302,GO:0065007,GO:0070085,GO:0071704,GO:0071840,GO:0098588,GO:0098796,GO:0098805,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990234	-	ko:K12667	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	-	-	ko00000,ko00001,ko00002	-	-	-	Ribophorin_II
k59_1214298_2	990285.RGCCGE502_24763	3.12e-33	120.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,4B9M6@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_469007_1	768671.ThimaDRAFT_2617	9.98e-87	263.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,1WWGI@135613|Chromatiales	135613|Chromatiales	KO	TIGRFAM Hydrogenase accessory protein HypB	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_900814_1	1260251.SPISAL_06805	2.49e-97	294.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1WVUV@135613|Chromatiales	135613|Chromatiales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_1174970_1	1307761.L21SP2_2654	9.41e-22	95.9	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_352349_1	247634.GPB2148_498	2.14e-26	114.0	COG0671@1|root,COG0671@2|Bacteria,1PX74@1224|Proteobacteria,1S52W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
k59_37880_1	335543.Sfum_3877	1.07e-35	129.0	COG1595@1|root,COG1595@2|Bacteria,1Q4ZK@1224|Proteobacteria,42TZB@68525|delta/epsilon subdivisions,2WR1D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1135315_1	595536.ADVE02000001_gene1023	9.16e-38	129.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,36YDS@31993|Methylocystaceae	28211|Alphaproteobacteria	O	Chaperonin 10 Kd subunit	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
k59_508673_1	765914.ThisiDRAFT_0124	3.8e-82	250.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,1S4HU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
k59_508673_2	765910.MARPU_11695	1.76e-50	174.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1WWDA@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k59_37904_1	1089548.KI783301_gene1263	1.03e-12	73.9	COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3WG73@539002|Bacillales incertae sedis	91061|Bacilli	EGP	Sugar (and other) transporter	bmr3	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_626860_1	84531.JMTZ01000032_gene310	3.41e-40	146.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1X2Y5@135614|Xanthomonadales	135614|Xanthomonadales	LU	DNA processing protein DprA	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
k59_626860_2	1121015.N789_06540	4.17e-17	76.6	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,1S43X@1236|Gammaproteobacteria,1X63Y@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
k59_1175032_1	130081.XP_005704889.1	7.38e-18	86.3	COG1080@1|root,2QREJ@2759|Eukaryota	2759|Eukaryota	G	pyruvate, phosphate dikinase activity	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_938656_1	314285.KT71_04550	2.46e-08	60.5	2EMUX@1|root,33FH7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_587286_1	247490.KSU1_D0195	1.11e-97	298.0	COG1032@1|root,COG1032@2|Bacteria,2IXHH@203682|Planctomycetes	203682|Planctomycetes	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_313063_1	880073.Calab_2460	1.33e-41	148.0	COG0446@1|root,COG0446@2|Bacteria,2NPPU@2323|unclassified Bacteria	2|Bacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
k59_1095552_1	748658.KB907316_gene525	2.27e-43	154.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1X2HB@135613|Chromatiales	135613|Chromatiales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_820594_1	1279017.AQYJ01000023_gene3158	3.85e-71	237.0	COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,464ZY@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_820594_2	1117647.M5M_06335	1.5e-18	83.6	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,1RS3G@1236|Gammaproteobacteria,1J55Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
k59_782917_1	1280685.AUKC01000028_gene654	6.17e-15	80.5	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,4BY0A@830|Butyrivibrio	186801|Clostridia	E	Glutamine amidotransferase domain	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_6,GATase_7
k59_782927_1	323261.Noc_1207	9.45e-30	116.0	28JVF@1|root,2Z9KD@2|Bacteria,1MXZ6@1224|Proteobacteria,1RY7E@1236|Gammaproteobacteria,1WX1M@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_704660_1	159087.Daro_1777	1.38e-58	200.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,2KXVT@206389|Rhodocyclales	206389|Rhodocyclales	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_704660_2	1265505.ATUG01000001_gene4178	2.8e-08	57.0	COG2009@1|root,2ZBTX@2|Bacteria,1RB22@1224|Proteobacteria,42NAY@68525|delta/epsilon subdivisions,2WMPM@28221|Deltaproteobacteria,2MJ7Q@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k59_195914_1	247634.GPB2148_1491	3.7e-79	245.0	COG1028@1|root,COG1028@2|Bacteria,1REA0@1224|Proteobacteria,1SMHH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_431022_1	220664.PFL_4949	1.24e-104	315.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,1YN5B@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_274300_1	935863.AWZR01000005_gene2439	2.11e-60	204.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1X3W8@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Activates fatty acids by binding to coenzyme A	rpfB	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_1136284_1	9402.XP_006911155.1	2.56e-119	345.0	KOG1735@1|root,KOG1735@2759|Eukaryota,39SM6@33154|Opisthokonta,3BB79@33208|Metazoa,3D0KZ@33213|Bilateria,488E8@7711|Chordata,48VG7@7742|Vertebrata,3J58S@40674|Mammalia	33208|Metazoa	Z	regulation of establishment of cell polarity regulating cell shape	CFL1	GO:0000910,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005938,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0007264,GO:0007265,GO:0007266,GO:0007275,GO:0007399,GO:0008092,GO:0008150,GO:0008154,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0010033,GO:0010769,GO:0010941,GO:0010975,GO:0016020,GO:0016043,GO:0019221,GO:0022008,GO:0022402,GO:0022411,GO:0022603,GO:0022604,GO:0023052,GO:0030027,GO:0030029,GO:0030036,GO:0030042,GO:0030154,GO:0030496,GO:0031252,GO:0031344,GO:0032501,GO:0032502,GO:0032984,GO:0034097,GO:0035556,GO:0035722,GO:0035821,GO:0042221,GO:0042981,GO:0042995,GO:0043066,GO:0043067,GO:0043069,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043624,GO:0043900,GO:0043902,GO:0043903,GO:0043933,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044788,GO:0044794,GO:0044877,GO:0045595,GO:0045664,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0050767,GO:0050773,GO:0050789,GO:0050792,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050896,GO:0051015,GO:0051128,GO:0051239,GO:0051261,GO:0051301,GO:0051702,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051851,GO:0051960,GO:0060284,GO:0060548,GO:0060998,GO:0061001,GO:0061640,GO:0065007,GO:0065008,GO:0070671,GO:0070887,GO:0071310,GO:0071345,GO:0071349,GO:0071840,GO:0071944,GO:0097435,GO:0099175,GO:0099568,GO:0120025,GO:0120035,GO:2000026	-	ko:K05765	ko04360,ko04666,ko04810,ko05133,map04360,map04666,map04810,map05133	-	-	-	ko00000,ko00001,ko04131,ko04147,ko04812	-	-	-	Cofilin_ADF
k59_431031_1	472759.Nhal_0531	7e-21	89.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1WYXK@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
k59_431040_1	1056512.D515_03353	4.05e-55	186.0	COG1757@1|root,COG1757@2|Bacteria,1MVDF@1224|Proteobacteria,1RS40@1236|Gammaproteobacteria,1XTWU@135623|Vibrionales	135623|Vibrionales	C	Na+/H+ antiporter family	-	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
k59_470230_1	1121013.P873_00360	1.16e-06	53.5	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,1X30A@135614|Xanthomonadales	135614|Xanthomonadales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
k59_470230_2	246195.DNO_0479	8.26e-14	70.5	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_587761_1	717785.HYPMC_2294	2.51e-88	275.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2TRXG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_78419_1	247639.MGP2080_04220	1.72e-44	156.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Signal transduction histidine kinase, nitrogen specific	glnL	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
k59_78419_2	1095769.CAHF01000018_gene793	8.66e-07	52.4	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,475BY@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Sigma-54 interaction domain	yfhA	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_744505_1	9606.ENSP00000380948	1.72e-109	335.0	KOG1226@1|root,KOG1226@2759|Eukaryota,38DSI@33154|Opisthokonta,3BA6T@33208|Metazoa,3D3JZ@33213|Bilateria,484MI@7711|Chordata,4957C@7742|Vertebrata,3J2HP@40674|Mammalia,359JS@314146|Euarchontoglires,4MHMT@9443|Primates,4N0FG@9604|Hominidae	33208|Metazoa	T	Integrin_b_cyt	ITGB2	GO:0000003,GO:0000902,GO:0000904,GO:0001505,GO:0001525,GO:0001540,GO:0001568,GO:0001667,GO:0001700,GO:0001703,GO:0001704,GO:0001706,GO:0001707,GO:0001708,GO:0001726,GO:0001774,GO:0001775,GO:0001846,GO:0001848,GO:0001851,GO:0001894,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001944,GO:0001968,GO:0002009,GO:0002011,GO:0002020,GO:0002064,GO:0002065,GO:0002066,GO:0002119,GO:0002164,GO:0002165,GO:0002218,GO:0002221,GO:0002224,GO:0002252,GO:0002253,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002520,GO:0002521,GO:0002523,GO:0002576,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0002697,GO:0002699,GO:0002703,GO:0002705,GO:0002757,GO:0002758,GO:0002764,GO:0002886,GO:0002888,GO:0003006,GO:0003008,GO:0003344,GO:0003674,GO:0003756,GO:0003779,GO:0003824,GO:0004888,GO:0005102,GO:0005126,GO:0005161,GO:0005172,GO:0005178,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005604,GO:0005605,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005886,GO:0005887,GO:0005902,GO:0005912,GO:0005924,GO:0005925,GO:0005927,GO:0006355,GO:0006810,GO:0006887,GO:0006897,GO:0006898,GO:0006909,GO:0006911,GO:0006915,GO:0006928,GO:0006929,GO:0006930,GO:0006935,GO:0006937,GO:0006940,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006968,GO:0006996,GO:0007010,GO:0007015,GO:0007154,GO:0007155,GO:0007156,GO:0007157,GO:0007159,GO:0007160,GO:0007161,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007229,GO:0007267,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007369,GO:0007377,GO:0007391,GO:0007399,GO:0007409,GO:0007411,GO:0007417,GO:0007419,GO:0007424,GO:0007426,GO:0007427,GO:0007431,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007483,GO:0007484,GO:0007485,GO:0007492,GO:0007494,GO:0007498,GO:0007507,GO:0007508,GO:0007517,GO:0007548,GO:0007552,GO:0007560,GO:0007568,GO:0007596,GO:0007599,GO:0007600,GO:0007606,GO:0007608,GO:0008092,GO:0008104,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008284,GO:0008305,GO:0008340,GO:0008360,GO:0008587,GO:0009605,GO:0009611,GO:0009653,GO:0009719,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009897,GO:0009925,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010004,GO:0010033,GO:0010243,GO:0010259,GO:0010324,GO:0010468,GO:0010469,GO:0010556,GO:0010558,GO:0010562,GO:0010594,GO:0010595,GO:0010604,GO:0010605,GO:0010631,GO:0010632,GO:0010634,GO:0010638,GO:0010646,GO:0010647,GO:0010648,GO:0010669,GO:0010710,GO:0010712,GO:0010720,GO:0010743,GO:0010745,GO:0010869,GO:0010871,GO:0010883,GO:0010888,GO:0010911,GO:0010912,GO:0010927,GO:0010941,GO:0010942,GO:0012501,GO:0012505,GO:0012506,GO:0014812,GO:0014909,GO:0015026,GO:0016020,GO:0016021,GO:0016032,GO:0016043,GO:0016192,GO:0016203,GO:0016323,GO:0016328,GO:0016331,GO:0016339,GO:0016340,GO:0016477,GO:0016853,GO:0016860,GO:0016864,GO:0017157,GO:0019058,GO:0019219,GO:0019220,GO:0019221,GO:0019222,GO:0019827,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0021551,GO:0022008,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030016,GO:0030017,GO:0030027,GO:0030029,GO:0030030,GO:0030031,GO:0030032,GO:0030036,GO:0030054,GO:0030055,GO:0030097,GO:0030098,GO:0030100,GO:0030101,GO:0030141,GO:0030154,GO:0030168,GO:0030175,GO:0030182,GO:0030183,GO:0030198,GO:0030239,GO:0030260,GO:0030334,GO:0030335,GO:0030336,GO:0030369,GO:0030425,GO:0030539,GO:0030593,GO:0030595,GO:0030659,GO:0030667,GO:0030707,GO:0030718,GO:0030855,GO:0030947,GO:0030949,GO:0031012,GO:0031032,GO:0031072,GO:0031090,GO:0031091,GO:0031092,GO:0031175,GO:0031224,GO:0031226,GO:0031252,GO:0031253,GO:0031256,GO:0031258,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031347,GO:0031349,GO:0031399,GO:0031401,GO:0031410,GO:0031430,GO:0031527,GO:0031528,GO:0031589,GO:0031594,GO:0031623,GO:0031672,GO:0031982,GO:0032147,GO:0032231,GO:0032268,GO:0032270,GO:0032368,GO:0032369,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032504,GO:0032587,GO:0032879,GO:0032880,GO:0032928,GO:0032930,GO:0032940,GO:0032943,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033157,GO:0033218,GO:0033238,GO:0033239,GO:0033627,GO:0033631,GO:0033674,GO:0034097,GO:0034103,GO:0034109,GO:0034113,GO:0034142,GO:0034446,GO:0034613,GO:0034665,GO:0034666,GO:0034667,GO:0034678,GO:0034680,GO:0034681,GO:0034683,GO:0034687,GO:0034688,GO:0035001,GO:0035099,GO:0035107,GO:0035112,GO:0035114,GO:0035120,GO:0035126,GO:0035152,GO:0035160,GO:0035162,GO:0035215,GO:0035220,GO:0035239,GO:0035272,GO:0035295,GO:0035579,GO:0035866,GO:0035867,GO:0035868,GO:0035987,GO:0036230,GO:0036477,GO:0038023,GO:0038027,GO:0040007,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0040025,GO:0040028,GO:0042053,GO:0042058,GO:0042059,GO:0042060,GO:0042069,GO:0042098,GO:0042110,GO:0042113,GO:0042116,GO:0042119,GO:0042127,GO:0042221,GO:0042277,GO:0042325,GO:0042327,GO:0042330,GO:0042383,GO:0042470,GO:0042581,GO:0042592,GO:0042692,GO:0042734,GO:0042802,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043030,GO:0043032,GO:0043034,GO:0043062,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043087,GO:0043112,GO:0043113,GO:0043170,GO:0043184,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043235,GO:0043277,GO:0043292,GO:0043299,GO:0043300,GO:0043302,GO:0043312,GO:0043313,GO:0043315,GO:0043519,GO:0043542,GO:0043547,GO:0043549,GO:0043900,GO:0043902,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044237,GO:0044260,GO:0044297,GO:0044403,GO:0044409,GO:0044419,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044853,GO:0044877,GO:0045055,GO:0045088,GO:0045089,GO:0045121,GO:0045123,GO:0045124,GO:0045165,GO:0045178,GO:0045202,GO:0045211,GO:0045214,GO:0045321,GO:0045428,GO:0045429,GO:0045595,GO:0045596,GO:0045597,GO:0045714,GO:0045715,GO:0045765,GO:0045766,GO:0045807,GO:0045859,GO:0045860,GO:0045914,GO:0045921,GO:0045933,GO:0045937,GO:0045963,GO:0045987,GO:0046649,GO:0046651,GO:0046661,GO:0046718,GO:0046850,GO:0046903,GO:0046982,GO:0046983,GO:0048010,GO:0048332,GO:0048333,GO:0048468,GO:0048477,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048563,GO:0048565,GO:0048568,GO:0048569,GO:0048580,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048598,GO:0048608,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048770,GO:0048803,GO:0048805,GO:0048806,GO:0048808,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0048871,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050746,GO:0050748,GO:0050764,GO:0050766,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050798,GO:0050803,GO:0050807,GO:0050817,GO:0050839,GO:0050840,GO:0050865,GO:0050867,GO:0050877,GO:0050878,GO:0050896,GO:0050900,GO:0050901,GO:0050919,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051051,GO:0051090,GO:0051091,GO:0051092,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051146,GO:0051147,GO:0051149,GO:0051153,GO:0051155,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051270,GO:0051271,GO:0051272,GO:0051336,GO:0051338,GO:0051345,GO:0051347,GO:0051492,GO:0051493,GO:0051495,GO:0051641,GO:0051668,GO:0051674,GO:0051701,GO:0051704,GO:0051716,GO:0051806,GO:0051828,GO:0051896,GO:0051897,GO:0051960,GO:0051962,GO:0055001,GO:0055002,GO:0055094,GO:0055120,GO:0055123,GO:0060039,GO:0060055,GO:0060089,GO:0060249,GO:0060255,GO:0060278,GO:0060279,GO:0060284,GO:0060297,GO:0060298,GO:0060326,GO:0060341,GO:0060429,GO:0060538,GO:0060541,GO:0060548,GO:0060560,GO:0060562,GO:0060627,GO:0061024,GO:0061061,GO:0061062,GO:0061458,GO:0061564,GO:0061756,GO:0061900,GO:0062023,GO:0065007,GO:0065008,GO:0065009,GO:0070161,GO:0070201,GO:0070527,GO:0070661,GO:0070727,GO:0070820,GO:0070821,GO:0070851,GO:0070887,GO:0070925,GO:0071062,GO:0071310,GO:0071345,GO:0071402,GO:0071404,GO:0071437,GO:0071438,GO:0071621,GO:0071704,GO:0071840,GO:0071944,GO:0072325,GO:0072327,GO:0072358,GO:0072359,GO:0072657,GO:0080090,GO:0080134,GO:0090087,GO:0090128,GO:0090129,GO:0090130,GO:0090132,GO:0090257,GO:0090287,GO:0090313,GO:0090314,GO:0090316,GO:0090322,GO:0090598,GO:0097060,GO:0097242,GO:0097386,GO:0097435,GO:0097447,GO:0097458,GO:0097485,GO:0097529,GO:0097530,GO:0097581,GO:0097708,GO:0098552,GO:0098588,GO:0098589,GO:0098590,GO:0098609,GO:0098631,GO:0098634,GO:0098636,GO:0098639,GO:0098657,GO:0098727,GO:0098742,GO:0098793,GO:0098794,GO:0098796,GO:0098797,GO:0098802,GO:0098805,GO:0098857,GO:0098858,GO:0099024,GO:0099080,GO:0099081,GO:0099503,GO:0099512,GO:0101002,GO:0101003,GO:0110020,GO:0110053,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0120039,GO:0140096,GO:1901184,GO:1901185,GO:1901214,GO:1901216,GO:1901342,GO:1901698,GO:1902115,GO:1902117,GO:1902531,GO:1902533,GO:1902563,GO:1902565,GO:1902903,GO:1902905,GO:1903076,GO:1903078,GO:1903305,GO:1903307,GO:1903354,GO:1903356,GO:1903426,GO:1903428,GO:1903506,GO:1903530,GO:1903532,GO:1903533,GO:1903827,GO:1903829,GO:1903978,GO:1903980,GO:1904018,GO:1904375,GO:1904377,GO:1904407,GO:1904901,GO:1904951,GO:1905475,GO:1905477,GO:1905952,GO:1905953,GO:1990266,GO:2000026,GO:2000112,GO:2000145,GO:2000146,GO:2000147,GO:2000209,GO:2000241,GO:2000243,GO:2000273,GO:2000361,GO:2000363,GO:2000377,GO:2000379,GO:2000811,GO:2001141	-	ko:K05719,ko:K06464,ko:K06493	ko04015,ko04145,ko04151,ko04360,ko04380,ko04390,ko04510,ko04512,ko04514,ko04530,ko04610,ko04611,ko04640,ko04650,ko04670,ko04810,ko04919,ko05100,ko05130,ko05131,ko05133,ko05134,ko05140,ko05144,ko05145,ko05146,ko05150,ko05152,ko05165,ko05166,ko05200,ko05205,ko05206,ko05222,ko05323,ko05410,ko05412,ko05414,ko05416,ko05418,map04015,map04145,map04151,map04360,map04380,map04390,map04510,map04512,map04514,map04530,map04610,map04611,map04640,map04650,map04670,map04810,map04919,map05100,map05130,map05131,map05133,map05134,map05140,map05144,map05145,map05146,map05150,map05152,map05165,map05166,map05200,map05205,map05206,map05222,map05323,map05410,map05412,map05414,map05416,map05418	-	-	-	ko00000,ko00001,ko04090,ko04131,ko04147,ko04516	-	-	-	EGF_2,Integrin_B_tail,Integrin_b_cyt,Integrin_beta,PSI_integrin
k59_1175495_1	404589.Anae109_2754	9.51e-91	278.0	COG1148@1|root,COG1148@2|Bacteria,1PTJ7@1224|Proteobacteria,42NJN@68525|delta/epsilon subdivisions,2WJHG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
k59_587788_1	935840.JAEQ01000001_gene2960	3.36e-05	45.8	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,43IMY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K10823,ko:K13896,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00349,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k59_587788_2	460265.Mnod_1116	9.2e-39	139.0	COG0791@1|root,COG0791@2|Bacteria,1MW03@1224|Proteobacteria,2TSFG@28211|Alphaproteobacteria,1JQU5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
k59_979614_1	926550.CLDAP_18280	9.55e-110	333.0	COG0747@1|root,COG0747@2|Bacteria,2G5NA@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_783725_2	1116472.MGMO_37c00170	7.2e-47	159.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1XDWR@135618|Methylococcales	135618|Methylococcales	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_666156_1	1517681.HW45_25635	3.59e-28	108.0	COG2067@1|root,COG2067@2|Bacteria,1NDQA@1224|Proteobacteria,1T61A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_666156_2	1280001.BAOA01000040_gene2474	1.17e-21	98.6	COG0729@1|root,COG0729@2|Bacteria,1R5Y3@1224|Proteobacteria,1RPB2@1236|Gammaproteobacteria,1XV4X@135623|Vibrionales	135623|Vibrionales	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
k59_1097175_1	1205753.A989_09551	8e-52	172.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1X3U9@135614|Xanthomonadales	135614|Xanthomonadales	K	RNA polymerase sigma factor RpoH	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
k59_1214716_1	1232437.KL662057_gene3906	1.23e-50	170.0	COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,42NTF@68525|delta/epsilon subdivisions,2X75Q@28221|Deltaproteobacteria,2MITK@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_548661_1	644801.Psest_2248	4e-26	100.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria,1Z31W@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	K	transcriptional	arsR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,LMWPc
k59_548661_2	1123368.AUIS01000014_gene2288	4.4e-29	107.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,1S2YD@1236|Gammaproteobacteria,2NCUY@225057|Acidithiobacillales	225057|Acidithiobacillales	T	low molecular weight	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_744541_1	1340493.JNIF01000003_gene1484	1.18e-56	199.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	iorB	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_1214722_3	1121396.KB892923_gene469	5.79e-17	73.9	28TI1@1|root,2ZFRW@2|Bacteria,1P8I1@1224|Proteobacteria,433I4@68525|delta/epsilon subdivisions,2WYHH@28221|Deltaproteobacteria,2MP65@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156828_1	1173028.ANKO01000111_gene4962	9.65e-14	70.9	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1G5@1117|Cyanobacteria,1H794@1150|Oscillatoriales	1117|Cyanobacteria	H	Tetratricopeptide repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_8
k59_450972_1	913865.DOT_3301	1.36e-20	94.4	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_1077281_1	1178482.BJB45_11560	8.61e-07	53.5	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1XHJ2@135619|Oceanospirillales	135619|Oceanospirillales	C	Domain of unknown function (DUF3483)	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
k59_1238376_1	1123376.AUIU01000015_gene432	3.16e-60	204.0	COG0744@1|root,COG0744@2|Bacteria,3J1FP@40117|Nitrospirae	40117|Nitrospirae	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_1077311_2	469378.Ccur_06230	8.97e-24	102.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CV2Q@84998|Coriobacteriia	84998|Coriobacteriia	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k59_177320_1	1305737.JAFX01000001_gene2007	1.41e-09	61.6	2DSTI@1|root,33HD4@2|Bacteria,4NYHV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_530460_1	566466.NOR53_2589	2.82e-12	65.9	COG2207@1|root,COG2207@2|Bacteria,1R73I@1224|Proteobacteria,1SYD3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k59_530460_2	1565129.JSFF01000001_gene1095	2.84e-57	194.0	COG1396@1|root,COG1396@2|Bacteria,1R3Z8@1224|Proteobacteria,1RRMV@1236|Gammaproteobacteria,2QAI5@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Transcriptional regulator, XRE family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3612,HTH_19,HTH_3,Peptidase_M78
k59_1077329_1	247634.GPB2148_110	1.39e-48	164.0	COG2207@1|root,COG2207@2|Bacteria,1RH01@1224|Proteobacteria,1S57M@1236|Gammaproteobacteria,1JAT7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	AraC-type DNA-binding domain-containing proteins	oruR	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k59_686448_1	1158150.KB906248_gene2248	5.04e-29	110.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1WVYN@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k59_686448_2	1049564.TevJSym_bq00030	1.69e-33	127.0	COG1385@1|root,COG4660@1|root,COG1385@2|Bacteria,COG4660@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1J5UQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_1238439_1	1209072.ALBT01000006_gene785	1.28e-51	172.0	COG0330@1|root,COG0330@2|Bacteria,1P8ZI@1224|Proteobacteria,1RUQU@1236|Gammaproteobacteria,1FI0E@10|Cellvibrio	1236|Gammaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_725685_2	1165096.ARWF01000001_gene1095	8.06e-79	237.0	COG0454@1|root,COG0456@2|Bacteria,1QUWI@1224|Proteobacteria,2WHDB@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_568678_1	1121015.N789_03965	4.76e-123	383.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1X3T3@135614|Xanthomonadales	135614|Xanthomonadales	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_842908_1	933262.AXAM01000005_gene2487	7.58e-65	207.0	COG1639@1|root,COG1639@2|Bacteria,1RKNA@1224|Proteobacteria,42TE8@68525|delta/epsilon subdivisions,2WPCE@28221|Deltaproteobacteria,2MPXW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_802912_1	643648.Slip_1570	2.71e-75	242.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,42KU5@68298|Syntrophomonadaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_882197_1	991905.SL003B_2625	9.81e-35	127.0	COG1796@1|root,COG1796@2|Bacteria,1QF8Z@1224|Proteobacteria	1224|Proteobacteria	L	Helix-hairpin-helix domain	dpbF	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_5,HHH_8
k59_99560_1	13735.ENSPSIP00000003006	7.89e-311	852.0	COG5023@1|root,KOG1376@2759|Eukaryota,38E06@33154|Opisthokonta,3BAUV@33208|Metazoa,3CRFN@33213|Bilateria,47ZHV@7711|Chordata,4901E@7742|Vertebrata,4CBJD@8459|Testudines	33208|Metazoa	Z	Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain	TUBA1B	GO:0001966,GO:0003008,GO:0003674,GO:0005198,GO:0005200,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005874,GO:0006996,GO:0007010,GO:0007017,GO:0007600,GO:0007610,GO:0007638,GO:0008150,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009987,GO:0015630,GO:0016043,GO:0030424,GO:0031644,GO:0031646,GO:0032101,GO:0032103,GO:0032501,GO:0036477,GO:0040011,GO:0042330,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044057,GO:0044297,GO:0044422,GO:0044424,GO:0044430,GO:0044446,GO:0044464,GO:0048518,GO:0048520,GO:0048583,GO:0048584,GO:0050789,GO:0050795,GO:0050877,GO:0050896,GO:0050906,GO:0050954,GO:0050974,GO:0050975,GO:0050976,GO:0050982,GO:0051239,GO:0051240,GO:0051606,GO:0051931,GO:0065007,GO:0071840,GO:0097458,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:1905787,GO:1905789,GO:1905790,GO:1905792	-	ko:K07374	ko04145,ko04210,ko04530,ko04540,ko05130,map04145,map04210,map04530,map04540,map05130	-	-	-	ko00000,ko00001,ko03019,ko03036,ko04147,ko04812	-	-	-	Tubulin,Tubulin_C
k59_373315_1	1120977.JHUX01000012_gene48	1.23e-10	61.6	COG0690@1|root,COG0690@2|Bacteria,1N4MA@1224|Proteobacteria,1S8XP@1236|Gammaproteobacteria,3NN4U@468|Moraxellaceae	1236|Gammaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
k59_920562_1	999611.KI421504_gene494	1.52e-31	125.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria,282GA@191028|Leisingera	28211|Alphaproteobacteria	L	Integrase core domain	istA	-	-	-	-	-	-	-	-	-	-	-	rve
k59_842952_1	717785.HYPMC_4378	3.09e-47	165.0	COG0477@1|root,COG2814@2|Bacteria,1R7QS@1224|Proteobacteria,2TUXM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_255775_2	861299.J421_2099	4.87e-13	73.9	COG1285@1|root,COG1285@2|Bacteria,1ZUVP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
k59_58772_1	9606.ENSP00000236671	6.34e-302	823.0	KOG1339@1|root,KOG1339@2759|Eukaryota,38D42@33154|Opisthokonta,3BBEX@33208|Metazoa,3CZ8C@33213|Bilateria,482WI@7711|Chordata,48Z3C@7742|Vertebrata,3JPJQ@40674|Mammalia,35HQH@314146|Euarchontoglires,4MFPT@9443|Primates,4N31W@9604|Hominidae	33208|Metazoa	O	Xylanase inhibitor C-terminal	CTSD	GO:0000003,GO:0000045,GO:0000323,GO:0001775,GO:0001894,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002478,GO:0002495,GO:0002504,GO:0003006,GO:0003674,GO:0003824,GO:0004175,GO:0004190,GO:0004197,GO:0004252,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005768,GO:0005770,GO:0005771,GO:0005773,GO:0005775,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006914,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007033,GO:0007276,GO:0007281,GO:0007292,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008234,GO:0008236,GO:0009056,GO:0009057,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0009991,GO:0010623,GO:0012501,GO:0012505,GO:0016020,GO:0016043,GO:0016192,GO:0016236,GO:0016787,GO:0017171,GO:0019538,GO:0019882,GO:0019884,GO:0019886,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0030141,GO:0030154,GO:0030163,GO:0030574,GO:0031410,GO:0031667,GO:0031904,GO:0031906,GO:0031974,GO:0031982,GO:0031983,GO:0032501,GO:0032502,GO:0032504,GO:0032940,GO:0032963,GO:0033218,GO:0033619,GO:0034774,GO:0035580,GO:0036230,GO:0042119,GO:0042277,GO:0042470,GO:0042581,GO:0042592,GO:0042599,GO:0042742,GO:0043129,GO:0043170,GO:0043202,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044437,GO:0044440,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045055,GO:0045121,GO:0045321,GO:0045476,GO:0046903,GO:0048002,GO:0048468,GO:0048477,GO:0048609,GO:0048770,GO:0048856,GO:0048869,GO:0048871,GO:0048875,GO:0048878,GO:0050829,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0060205,GO:0060249,GO:0061919,GO:0065007,GO:0065008,GO:0070001,GO:0070011,GO:0070013,GO:0070265,GO:0070820,GO:0070925,GO:0071704,GO:0071840,GO:0097208,GO:0097486,GO:0097708,GO:0098542,GO:0098589,GO:0098805,GO:0098857,GO:0099503,GO:0101002,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902742,GO:1904724,GO:1904813,GO:1905037	3.4.23.34,3.4.23.5	ko:K01379,ko:K01382,ko:K08565	ko04071,ko04140,ko04142,ko04210,ko04915,ko05152,map04071,map04140,map04142,map04210,map04915,map05152	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	A1_Propeptide,Asp
k59_490566_1	460265.Mnod_5308	8.15e-102	314.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,1JS6I@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_1042041_1	1121127.JAFA01000001_gene1011	2.78e-90	275.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,1K2VU@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_725812_1	991905.SL003B_0537	9.63e-82	258.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,4BP9G@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	MA20_29420	-	6.2.1.48	ko:K00666,ko:K02182	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_608676_1	395493.BegalDRAFT_0253	4.47e-54	185.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4607S@72273|Thiotrichales	72273|Thiotrichales	T	nitrogen regulation protein NR(I)	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_960933_1	65071.PYU1_T003042	2.78e-18	80.1	2CXQD@1|root,2RZ24@2759|Eukaryota,1MGWP@121069|Pythiales	121069|Pythiales	S	Lactoylglutathione lyase. Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
k59_960933_2	1232666.JANE01000036_gene1968	6.25e-25	102.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,4GXR6@90964|Staphylococcaceae	91061|Bacilli	I	Malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_416014_1	1158050.KB895452_gene365	3.72e-11	63.5	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,1W7U5@1268|Micrococcaceae	201174|Actinobacteria	E	ABC transporter	proV	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	iNJ661.Rv3758c	ABC_tran
k59_416014_2	1453501.JELR01000002_gene1227	1.06e-37	138.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,464WP@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
k59_530732_1	159087.Daro_2878	1.6e-29	115.0	COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,2VIK0@28216|Betaproteobacteria,2KVSE@206389|Rhodocyclales	206389|Rhodocyclales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1117577_1	933262.AXAM01000008_gene1978	1.87e-96	285.0	COG1392@1|root,COG1392@2|Bacteria,1MXY9@1224|Proteobacteria,42NPT@68525|delta/epsilon subdivisions,2WKR0@28221|Deltaproteobacteria,2MHNF@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
k59_1238658_1	187272.Mlg_2261	2.58e-66	221.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1WVWH@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_1242308_2	1283300.ATXB01000001_gene1620	4.82e-79	245.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1XEVT@135618|Methylococcales	135618|Methylococcales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_454435_1	9606.ENSP00000313420	4.12e-108	346.0	COG5032@1|root,KOG0891@2759|Eukaryota,39P1Q@33154|Opisthokonta,3BBCQ@33208|Metazoa,3CY0U@33213|Bilateria,4832X@7711|Chordata,492HY@7742|Vertebrata,3J8SG@40674|Mammalia,35C9K@314146|Euarchontoglires,4MC78@9443|Primates,4N3X8@9604|Hominidae	33208|Metazoa	L	NUC194	PRKDC	GO:0000003,GO:0000075,GO:0000077,GO:0000278,GO:0000723,GO:0000724,GO:0000725,GO:0000726,GO:0001756,GO:0001775,GO:0001817,GO:0001819,GO:0001932,GO:0001933,GO:0002200,GO:0002218,GO:0002244,GO:0002253,GO:0002320,GO:0002326,GO:0002328,GO:0002360,GO:0002376,GO:0002377,GO:0002440,GO:0002520,GO:0002521,GO:0002562,GO:0002568,GO:0002637,GO:0002638,GO:0002681,GO:0002682,GO:0002683,GO:0002684,GO:0002697,GO:0002698,GO:0002700,GO:0002701,GO:0003002,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004672,GO:0004674,GO:0004677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005667,GO:0005730,GO:0005737,GO:0005829,GO:0005958,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006310,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007093,GO:0007154,GO:0007165,GO:0007275,GO:0007346,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008284,GO:0008630,GO:0009314,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009952,GO:0009987,GO:0010033,GO:0010212,GO:0010243,GO:0010332,GO:0010468,GO:0010556,GO:0010557,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010623,GO:0010628,GO:0010941,GO:0010942,GO:0010948,GO:0012501,GO:0016043,GO:0016233,GO:0016301,GO:0016310,GO:0016444,GO:0016445,GO:0016447,GO:0016567,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018193,GO:0018209,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019904,GO:0022402,GO:0022414,GO:0023052,GO:0030097,GO:0030098,GO:0030154,GO:0030183,GO:0030217,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031347,GO:0031349,GO:0031399,GO:0031400,GO:0031570,GO:0031571,GO:0031647,GO:0031648,GO:0031974,GO:0031981,GO:0032200,GO:0032268,GO:0032269,GO:0032446,GO:0032479,GO:0032481,GO:0032501,GO:0032502,GO:0032868,GO:0032869,GO:0032870,GO:0032991,GO:0032993,GO:0033077,GO:0033151,GO:0033152,GO:0033153,GO:0033554,GO:0034641,GO:0035234,GO:0035282,GO:0035556,GO:0036211,GO:0040008,GO:0042110,GO:0042113,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0042592,GO:0042752,GO:0042770,GO:0042981,GO:0043009,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043434,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044773,GO:0044774,GO:0044783,GO:0044819,GO:0045088,GO:0045089,GO:0045165,GO:0045321,GO:0045786,GO:0045893,GO:0045927,GO:0045930,GO:0045935,GO:0045936,GO:0045944,GO:0046483,GO:0046649,GO:0048145,GO:0048146,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048536,GO:0048538,GO:0048583,GO:0048584,GO:0048585,GO:0048638,GO:0048639,GO:0048646,GO:0048660,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051093,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051276,GO:0051716,GO:0051726,GO:0060249,GO:0060255,GO:0060322,GO:0060429,GO:0060548,GO:0061053,GO:0065007,GO:0065008,GO:0070013,GO:0070419,GO:0070647,GO:0070887,GO:0071310,GO:0071375,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0072359,GO:0072395,GO:0072401,GO:0072413,GO:0072422,GO:0072431,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090342,GO:0090344,GO:0097159,GO:0097190,GO:0097193,GO:0097681,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902400,GO:1902402,GO:1902403,GO:1902680,GO:1902806,GO:1902807,GO:1903047,GO:1903506,GO:1903508,GO:1990391,GO:2000045,GO:2000112,GO:2000134,GO:2000772,GO:2000773,GO:2001141,GO:2001228,GO:2001229	2.7.11.1	ko:K06642	ko03450,ko04110,map03450,map04110	M00297	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko03032,ko03400	-	-	-	FAT,FATC,NUC194,PI3_PI4_kinase
k59_376709_2	1348663.KCH_08270	7.96e-44	155.0	COG1794@1|root,COG1794@2|Bacteria,2H7J9@201174|Actinobacteria,2M1AQ@2063|Kitasatospora	201174|Actinobacteria	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
k59_846432_1	1150474.JQJI01000021_gene2038	3.12e-12	74.3	COG4733@1|root,COG4886@1|root,COG4733@2|Bacteria,COG4886@2|Bacteria,2GE91@200918|Thermotogae	2|Bacteria	M	Fibronectin type III domain	-	-	2.7.11.1	ko:K03933,ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	AA10,CBM73	-	Big_4,CW_binding_2,fn3
k59_1008586_1	1117647.M5M_05960	1.65e-53	189.0	COG4774@1|root,COG4774@2|Bacteria,1MX2G@1224|Proteobacteria,1RYSK@1236|Gammaproteobacteria,1J7TN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_62038_1	444860.E3SJ54_9CAUD	1.1e-98	298.0	4QDUC@10239|Viruses,4QV7K@35237|dsDNA viruses  no RNA stage,4QR22@28883|Caudovirales,4QJ6D@10662|Myoviridae	10662|Myoviridae	S	transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_572084_1	1415778.JQMM01000001_gene137	2.98e-53	177.0	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,1RRR0@1236|Gammaproteobacteria,1J84B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Proteasome subunit	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
k59_454467_1	1123400.KB904749_gene770	5.54e-86	262.0	COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,1RQDX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	sterol desaturase	erg	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
k59_1242349_1	1245469.S58_08340	3.5e-19	94.0	COG2176@1|root,COG2176@2|Bacteria,1QUVW@1224|Proteobacteria,2TSZS@28211|Alphaproteobacteria,3JTBA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	VRR_NUC	polC	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T,VRR_NUC
k59_103145_1	1189612.A33Q_0323	1.64e-66	221.0	COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_420540_1	1121396.KB892990_gene4477	1.09e-67	228.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1QFX3@1224|Proteobacteria,42PIP@68525|delta/epsilon subdivisions,2WKWI@28221|Deltaproteobacteria,2MIZ0@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_1159922_1	269799.Gmet_0109	3.04e-59	196.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2WKJ2@28221|Deltaproteobacteria,43S3B@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
k59_1159922_2	56780.SYN_01922	0.000146	42.4	2APA5@1|root,31EC7@2|Bacteria,1RHMQ@1224|Proteobacteria,42UND@68525|delta/epsilon subdivisions,2WQK4@28221|Deltaproteobacteria,2MS7K@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_494064_1	876044.IMCC3088_857	9.75e-76	238.0	COG2304@1|root,COG2304@2|Bacteria,1QBPM@1224|Proteobacteria,1RQIU@1236|Gammaproteobacteria,1J4PZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Secreted protein, containing von Willebrand factor (VWF) type	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_222063_1	411684.HPDFL43_10022	9.14e-93	278.0	COG3639@1|root,COG3639@2|Bacteria,1MUD6@1224|Proteobacteria,2TTVG@28211|Alphaproteobacteria,43KG2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	phnE_2	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
k59_1044834_1	1128421.JAGA01000002_gene996	3.23e-64	211.0	COG0064@1|root,COG0064@2|Bacteria,2NNPK@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.12,6.3.5.6,6.3.5.7	ko:K01876,ko:K02434	ko00970,ko01100,map00970,map01100	M00359,M00360	R03905,R04212,R05577	RC00010,RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,GatB_N,GatB_Yqey,tRNA-synt_2,tRNA_anti-codon
k59_376800_1	523794.Lebu_0713	1.58e-17	81.3	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	VY92_08700	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_337264_1	754477.Q7C_1945	1.56e-62	206.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,46000@72273|Thiotrichales	72273|Thiotrichales	P	TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_454540_1	1122135.KB893134_gene3207	1.95e-94	295.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	gsiA1	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_690049_1	78245.Xaut_4843	9.89e-150	438.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2U4DT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_572182_1	1382305.AZUC01000016_gene2717	1.71e-12	72.4	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,26CVN@186818|Planococcaceae	91061|Bacilli	S	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like	yabN	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
k59_1120959_1	1123073.KB899241_gene2060	6.16e-89	277.0	COG0006@1|root,COG0006@2|Bacteria,1MURT@1224|Proteobacteria,1RMKT@1236|Gammaproteobacteria,1X3Z6@135614|Xanthomonadales	135614|Xanthomonadales	E	Splits dipeptides with a prolyl residue in the C- terminal position	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_535610_1	1121937.AUHJ01000009_gene1553	5.29e-99	305.0	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,1RNS0@1236|Gammaproteobacteria,46ADA@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Cytochrome D1 heme domain	nirS	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
k59_767994_1	997346.HMPREF9374_1022	2.01e-43	153.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,27AU8@186824|Thermoactinomycetaceae	91061|Bacilli	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
k59_923950_1	1118153.MOY_08042	2.07e-14	72.8	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XIU0@135619|Oceanospirillales	135619|Oceanospirillales	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_923950_2	583355.Caka_2620	4.21e-153	457.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
k59_1120965_1	553385.JEMF01000039_gene2894	3.32e-87	271.0	COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,1RSR2@1236|Gammaproteobacteria,1XIA6@135619|Oceanospirillales	135619|Oceanospirillales	FH	cytosine purines uracil thiamine allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
k59_1242455_1	85643.Tmz1t_2301	4.68e-74	240.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2VH5R@28216|Betaproteobacteria,2KUU7@206389|Rhodocyclales	206389|Rhodocyclales	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_222161_1	870187.Thini_3317	2.45e-07	49.3	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,460UB@72273|Thiotrichales	72273|Thiotrichales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_222161_2	631362.Thi970DRAFT_01961	1.26e-49	158.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria,1WYHJ@135613|Chromatiales	135613|Chromatiales	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k59_222161_3	1278309.KB907106_gene1316	6.44e-109	320.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1XHKX@135619|Oceanospirillales	135619|Oceanospirillales	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_1044893_1	194439.CT2081	5.81e-70	225.0	COG0446@1|root,COG0446@2|Bacteria,1FDM3@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2
k59_298784_1	69279.BG36_04905	1.11e-91	276.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2TS7B@28211|Alphaproteobacteria,43JQ6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_103267_1	768671.ThimaDRAFT_2843	2.96e-09	59.7	COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,1RSD7@1236|Gammaproteobacteria,1WXR6@135613|Chromatiales	135613|Chromatiales	S	Fusaric acid resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_885899_1	555778.Hneap_2214	2.39e-104	318.0	COG3547@1|root,COG3547@2|Bacteria,1QYJU@1224|Proteobacteria,1RN0A@1236|Gammaproteobacteria,1WZMA@135613|Chromatiales	135613|Chromatiales	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_535679_2	1121441.AUCX01000002_gene2876	2.39e-19	82.4	COG1550@1|root,COG1550@2|Bacteria,1NEW6@1224|Proteobacteria,42V11@68525|delta/epsilon subdivisions,2WSHI@28221|Deltaproteobacteria,2MC56@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
k59_535679_3	335543.Sfum_1230	1.46e-17	77.4	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,42VQ6@68525|delta/epsilon subdivisions,2WRTU@28221|Deltaproteobacteria,2MQNU@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
k59_140838_1	1278304.JAFR01000011_gene1004	2.85e-19	92.4	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	-	-	-	-	-	-	-	-	-	-	-	-	DegV
k59_1160056_1	555079.Toce_2133	3.72e-80	259.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,42F6G@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
k59_1008832_1	580340.Tlie_0511	3.15e-21	96.7	COG2423@1|root,COG2423@2|Bacteria,3TB9R@508458|Synergistetes	508458|Synergistetes	E	PFAM Ornithine cyclodeaminase mu-crystallin	-	-	1.5.1.51	ko:K21721	-	-	-	-	ko00000,ko01000	-	-	-	OCD_Mu_crystall
k59_420764_1	1187851.A33M_1391	2.26e-54	193.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1144@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1144@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,2U2F7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_1160092_1	395493.BegalDRAFT_1422	3.46e-107	339.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,45ZPA@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_259509_1	1123393.KB891316_gene1239	1.67e-66	207.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,2VRAN@28216|Betaproteobacteria,1KTF2@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k59_1199543_1	1255043.TVNIR_2190	9.62e-65	216.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1WWKW@135613|Chromatiales	135613|Chromatiales	K	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
k59_806344_1	270374.MELB17_01135	5.82e-74	230.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1S1WF@1236|Gammaproteobacteria,465E7@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_711545_2	1167006.UWK_03322	4.67e-87	263.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,42QAT@68525|delta/epsilon subdivisions,2WJMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k59_868351_1	502025.Hoch_4083	6.49e-38	138.0	COG0697@1|root,COG0697@2|Bacteria,1PIFM@1224|Proteobacteria,4349X@68525|delta/epsilon subdivisions,2X51H@28221|Deltaproteobacteria,2Z2H2@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_907639_1	1121935.AQXX01000108_gene451	5.06e-10	63.2	COG3203@1|root,COG3203@2|Bacteria,1RIIY@1224|Proteobacteria,1T112@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_1142780_1	595537.Varpa_0834	2.55e-27	107.0	COG1309@1|root,COG1309@2|Bacteria,1R6RX@1224|Proteobacteria,2VKE3@28216|Betaproteobacteria,4ABAH@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_319908_1	391589.RGAI101_3656	1.77e-37	139.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2V8EI@28211|Alphaproteobacteria,2P4RH@2433|Roseobacter	28211|Alphaproteobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
k59_633784_1	744980.TRICHSKD4_4039	3.94e-69	213.0	COG1522@1|root,COG1522@2|Bacteria,1RDB3@1224|Proteobacteria,2U580@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	ko:K05800	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
k59_672686_1	589865.DaAHT2_1451	1.29e-60	194.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,42MPW@68525|delta/epsilon subdivisions,2WN96@28221|Deltaproteobacteria,2MJHZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_85635_1	365528.KB891239_gene6024	2.67e-05	44.7	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
k59_163460_1	768671.ThimaDRAFT_0873	1.02e-14	73.9	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGB@1236|Gammaproteobacteria,1X1MI@135613|Chromatiales	135613|Chromatiales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_946872_1	1267005.KB911255_gene3037	2.17e-55	190.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2U0K2@28211|Alphaproteobacteria,3N6RA@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_163462_1	926569.ANT_23480	9.39e-71	237.0	COG0209@1|root,COG0209@2|Bacteria,2G5PW@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
k59_829318_1	439235.Dalk_1208	1.4e-86	275.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria,2MIMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_751043_1	1009370.ALO_12811	6.39e-12	70.9	COG0419@1|root,COG0419@2|Bacteria,1TP6S@1239|Firmicutes	1239|Firmicutes	L	ATPase involved in DNA repair	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Metallophos
k59_398799_2	378806.STAUR_3125	9.44e-14	67.4	COG3324@1|root,COG3324@2|Bacteria,1N0AD@1224|Proteobacteria,434XT@68525|delta/epsilon subdivisions,2WZ8M@28221|Deltaproteobacteria,2Z1K6@29|Myxococcales	28221|Deltaproteobacteria	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_907707_1	61853.ENSNLEP00000014973	1.17e-57	201.0	KOG3792@1|root,KOG3792@2759|Eukaryota,39SGY@33154|Opisthokonta,3BBQY@33208|Metazoa,3D2GF@33213|Bilateria,486T1@7711|Chordata,498R9@7742|Vertebrata,3JBUS@40674|Mammalia,35IQ2@314146|Euarchontoglires,4MF3X@9443|Primates	33208|Metazoa	K	Interleukin enhancer binding factor 3	ILF3	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0003723,GO:0003725,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005739,GO:0006355,GO:0006417,GO:0006464,GO:0006468,GO:0006479,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008213,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016310,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043900,GO:0043901,GO:0043903,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045069,GO:0045071,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048525,GO:0050789,GO:0050792,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1903900,GO:1903901,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K13090	-	-	-	-	ko00000,ko03041	-	-	-	DZF,dsrm
k59_163504_1	1167006.UWK_01150	1.17e-114	348.0	COG2070@1|root,COG2070@2|Bacteria,1R8ZS@1224|Proteobacteria,42N1N@68525|delta/epsilon subdivisions,2WMIF@28221|Deltaproteobacteria,2MMMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_282625_1	340099.Teth39_0747	3.93e-25	95.9	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia,42H6Q@68295|Thermoanaerobacterales	186801|Clostridia	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
k59_988544_1	1173022.Cri9333_4060	7.36e-56	192.0	COG0296@1|root,COG0296@2|Bacteria,1GD05@1117|Cyanobacteria,1HEAH@1150|Oscillatoriales	1117|Cyanobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_674585_2	582899.Hden_0389	9.69e-07	50.8	COG1073@1|root,COG1073@2|Bacteria,1MX88@1224|Proteobacteria,2TSRE@28211|Alphaproteobacteria,3N6T9@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	MA20_24420	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4
k59_282637_1	243277.VC_0629	5.14e-103	331.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XU61@135623|Vibrionales	135623|Vibrionales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
k59_165370_1	1121405.dsmv_0666	1.03e-67	221.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2MI66@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_321862_1	187272.Mlg_0737	7.28e-81	252.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1WWRK@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_635610_1	1366050.N234_03565	5.68e-53	183.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria,1K51A@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3,SLT
k59_400694_1	324602.Caur_3745	6.88e-97	301.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_909459_1	335543.Sfum_2329	1.99e-62	197.0	COG2819@1|root,COG2819@2|Bacteria,1RAB4@1224|Proteobacteria,42WZ1@68525|delta/epsilon subdivisions,2WTDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
k59_47711_1	281090.Lxx06030	7.86e-14	75.9	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4FKC3@85023|Microbacteriaceae	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_988641_1	700598.Niako_5403	4.45e-10	65.5	COG3386@1|root,COG3386@2|Bacteria,4PNUT@976|Bacteroidetes	976|Bacteroidetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	NHL
k59_126302_1	882.DVU_2318	3.35e-23	93.6	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions,2WN92@28221|Deltaproteobacteria,2M9VS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_126302_2	880072.Desac_2162	3.57e-16	72.0	2DE9Q@1|root,2ZM3Z@2|Bacteria,1P405@1224|Proteobacteria,432RK@68525|delta/epsilon subdivisions,2WYEV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_635636_1	1120965.AUBV01000014_gene1227	5.65e-65	214.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,47NKR@768503|Cytophagia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
k59_988662_1	566466.NOR53_3038	1.1e-41	150.0	28M5H@1|root,2ZAJ9@2|Bacteria,1RJY2@1224|Proteobacteria,1SM8E@1236|Gammaproteobacteria,1J7EK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_988673_1	1122194.AUHU01000016_gene1872	2.16e-112	332.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,4644Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	adhC	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_439668_1	27923.ML063336a-PA	9.32e-19	90.5	COG0349@1|root,KOG2206@2759|Eukaryota,38D24@33154|Opisthokonta,3BK12@33208|Metazoa	33208|Metazoa	J	exosome component 10	EXOSC10	GO:0000175,GO:0000176,GO:0000178,GO:0000278,GO:0000460,GO:0000737,GO:0000785,GO:0000956,GO:0002252,GO:0002376,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005652,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006309,GO:0006364,GO:0006378,GO:0006396,GO:0006397,GO:0006401,GO:0006402,GO:0006403,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006909,GO:0006915,GO:0006921,GO:0006950,GO:0006952,GO:0007049,GO:0007059,GO:0007275,GO:0007549,GO:0008150,GO:0008152,GO:0008219,GO:0008298,GO:0008334,GO:0008408,GO:0009048,GO:0009056,GO:0009057,GO:0009605,GO:0009607,GO:0009615,GO:0009790,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010639,GO:0012501,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016192,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019219,GO:0019222,GO:0019439,GO:0022411,GO:0022613,GO:0030262,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032204,GO:0032205,GO:0032210,GO:0032211,GO:0032501,GO:0032502,GO:0032879,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0034399,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0035327,GO:0040029,GO:0042254,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043277,GO:0043631,GO:0043632,GO:0043633,GO:0043634,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051607,GO:0051641,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0065008,GO:0070013,GO:0070034,GO:0070727,GO:0071025,GO:0071027,GO:0071028,GO:0071029,GO:0071030,GO:0071033,GO:0071034,GO:0071035,GO:0071043,GO:0071044,GO:0071046,GO:0071048,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097194,GO:0098542,GO:0098657,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1904356,GO:1904357,GO:1904872,GO:1905354,GO:2000112,GO:2000113,GO:2000278,GO:2000279,GO:2001251	-	ko:K12591	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DNA_pol_A_exo1,HRDC,PMC2NT
k59_165434_1	1380390.JIAT01000015_gene5738	8.45e-24	97.4	COG1309@1|root,COG1309@2|Bacteria,2GJPK@201174|Actinobacteria,4CU34@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
k59_948893_1	1267005.KB911257_gene986	4.2e-73	244.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria,3N6KE@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_1105841_1	1300345.LF41_3143	2.43e-121	362.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1X393@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	-	-	-	-	-	-	-	-	-	-	PALP
k59_47765_1	1521187.JPIM01000021_gene145	5.65e-18	88.2	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
k59_8688_1	909663.KI867150_gene248	5.46e-80	253.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2MQT7@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.18,1.2.1.20,1.2.1.27,1.2.1.3,1.2.1.79,1.2.1.9	ko:K00128,ko:K00131,ko:K00135,ko:K00140	ko00010,ko00030,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00562,ko00620,ko00625,ko00640,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00562,map00620,map00625,map00640,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130,map01200	M00013,M00027,M00135,M00308,M00633	R00264,R00631,R00705,R00706,R00710,R00713,R00714,R00904,R00922,R00935,R01058,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00004,RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_204325_1	498211.CJA_0295	1.73e-37	146.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1FG1C@10|Cellvibrio	1236|Gammaproteobacteria	CH	FAD binding domain	ubiH	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008681,GO:0009058,GO:0009108,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016705,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0050896,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663	-	ko:K03185,ko:K18800	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04987,R04989,R08768,R08773	RC00046,RC02670	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_02702,iECBD_1354.ECBD_0830,iECB_1328.ECB_02739,iECD_1391.ECD_02739,iEcHS_1320.EcHS_A3066	FAD_binding_3
k59_439695_1	377629.TERTU_1092	7.94e-76	242.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,2PPF3@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_361701_1	177437.HRM2_10830	4.51e-81	263.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
k59_713849_2	543728.Vapar_2017	2.75e-29	110.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,4ABNT@80864|Comamonadaceae	28216|Betaproteobacteria	F	Nudix hydrolase	nudC_1	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
k59_47811_2	1245471.PCA10_24360	1.06e-21	92.4	COG2197@1|root,COG2197@2|Bacteria,1RDI0@1224|Proteobacteria,1RS5N@1236|Gammaproteobacteria,1YJ8H@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_1066488_1	933262.AXAM01000040_gene1226	8.38e-45	164.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2MI1W@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
k59_1028022_1	177437.HRM2_39480	9.98e-37	147.0	COG3385@1|root,COG3385@2|Bacteria,1RM2A@1224|Proteobacteria,42WE3@68525|delta/epsilon subdivisions,2X6QW@28221|Deltaproteobacteria,2MN97@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_792200_2	876044.IMCC3088_1388	8.17e-22	92.4	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1J54C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECS88_1305.ECS88_0100	LpxC
k59_1105880_1	1415166.NONO_c41630	5.25e-06	53.9	COG1309@1|root,COG1309@2|Bacteria,2GMWH@201174|Actinobacteria,4G01S@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_165492_1	1123073.KB899241_gene2625	3.55e-26	111.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1X497@135614|Xanthomonadales	135614|Xanthomonadales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_204362_1	338969.Rfer_4073	9.81e-83	268.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,2VKG8@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1105903_2	87626.PTD2_05335	8.72e-05	52.4	COG0823@1|root,COG0823@2|Bacteria,1MZHN@1224|Proteobacteria	1224|Proteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
k59_870413_1	1380394.JADL01000002_gene1785	1.18e-23	100.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2U2BQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
k59_988804_1	187272.Mlg_0481	6.54e-41	137.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,1WYDZ@135613|Chromatiales	135613|Chromatiales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_988804_2	935863.AWZR01000003_gene2903	1e-54	176.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1X3DJ@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_47884_1	1042209.HK44_021600	4.4e-71	225.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,1RRMU@1236|Gammaproteobacteria,1YU3Y@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	L	Endonuclease DDE	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_32
k59_47896_2	1441930.Z042_06730	5.11e-09	56.2	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,400W1@613|Serratia	1236|Gammaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298	5-FTHF_cyc-lig
k59_8778_1	1177154.Y5S_01937	2.65e-14	73.6	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XHXU@135619|Oceanospirillales	135619|Oceanospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_8778_2	983545.Glaag_2331	1.93e-06	52.0	COG0845@1|root,COG0845@2|Bacteria,1R443@1224|Proteobacteria,1RYSM@1236|Gammaproteobacteria,465RJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_948999_1	1304284.L21TH_1970	4.04e-59	191.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,36DMA@31979|Clostridiaceae	186801|Clostridia	E	Glutamate formiminotransferase	ftcD	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
k59_204410_1	237368.SCABRO_01667	1.23e-11	70.1	COG3930@1|root,COG3930@2|Bacteria,2J4QT@203682|Planctomycetes	203682|Planctomycetes	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
k59_674796_1	345341.KUTG_04234	6.95e-116	339.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
k59_635775_1	1267005.KB911266_gene1250	2.86e-161	462.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,3N7U4@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_635775_2	391616.OA238_c40160	2.41e-24	99.8	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2UDDB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_282880_1	465515.Mlut_11280	2.39e-49	177.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,1W8FQ@1268|Micrococcaceae	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_165576_1	644282.Deba_0734	4.1e-86	267.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_400917_1	1417296.U879_08075	1.56e-53	181.0	COG2048@1|root,COG2048@2|Bacteria,1R97P@1224|Proteobacteria,2TSIB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
k59_400917_2	1255043.TVNIR_3247	1.66e-26	106.0	COG0446@1|root,COG1148@1|root,COG0446@2|Bacteria,COG1148@2|Bacteria,1R882@1224|Proteobacteria,1SAD3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
k59_1184458_1	1304275.C41B8_01320	9.09e-66	213.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
k59_1184458_2	236097.ADG881_2130	1.38e-22	90.1	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1XKFN@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
k59_478936_1	1313172.YM304_07450	4.03e-80	258.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_322101_2	243160.BMAA1696	1.55e-20	84.0	2DP59@1|root,330K4@2|Bacteria,1NEEA@1224|Proteobacteria,2VXKK@28216|Betaproteobacteria,1KHFB@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1106010_1	1121396.KB893078_gene786	1.72e-83	263.0	COG4467@1|root,COG4467@2|Bacteria,1PPMF@1224|Proteobacteria	1224|Proteobacteria	S	Involved in initiation control of chromosome replication	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66
k59_831446_1	227086.JGI_V11_68802	0.000749	44.3	2CYNH@1|root,2S5BK@2759|Eukaryota	2759|Eukaryota	-	-	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
k59_423760_1	639283.Snov_3684	1.44e-68	221.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2TRKB@28211|Alphaproteobacteria,3EZ65@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
k59_1101984_1	118797.XP_007465796.1	0.0	1198.0	KOG0123@1|root,KOG0123@2759|Eukaryota,38F9F@33154|Opisthokonta,3BB3Q@33208|Metazoa,3CUUM@33213|Bilateria,481K5@7711|Chordata,496B9@7742|Vertebrata,3JCBK@40674|Mammalia,4IVQQ@91561|Cetartiodactyla	33208|Metazoa	AJ	Polyadenylate-binding protein	PABPC1	GO:0000184,GO:0000375,GO:0000377,GO:0000398,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003729,GO:0003730,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005681,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006417,GO:0006518,GO:0006725,GO:0006807,GO:0008022,GO:0008143,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0008380,GO:0008494,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009896,GO:0009987,GO:0010467,GO:0010468,GO:0010494,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016070,GO:0016071,GO:0016458,GO:0019219,GO:0019222,GO:0019439,GO:0019538,GO:0030425,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034655,GO:0035770,GO:0036464,GO:0036477,GO:0042995,GO:0043005,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043487,GO:0043488,GO:0043489,GO:0043603,GO:0043604,GO:0043631,GO:0043900,GO:0043902,GO:0043903,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0045069,GO:0045070,GO:0045182,GO:0045727,GO:0045934,GO:0045935,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0050789,GO:0050792,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0060211,GO:0060213,GO:0060255,GO:0061013,GO:0061014,GO:0065007,GO:0065008,GO:0070717,GO:0071013,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097447,GO:0097458,GO:0120025,GO:0120038,GO:1900151,GO:1900153,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902369,GO:1902373,GO:1902494,GO:1903311,GO:1903312,GO:1903313,GO:1903900,GO:1903902,GO:1990124,GO:1990904,GO:2000112,GO:2000622,GO:2000623	-	ko:K13126	ko03013,ko03015,ko03018,map03013,map03015,map03018	-	-	-	ko00000,ko00001,ko03019,ko03041	-	-	-	PABP,RRM_1
k59_866740_1	1379701.JPJC01000157_gene554	8.67e-20	90.1	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TSEI@28211|Alphaproteobacteria,2K13V@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	bkdA1	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoDH_E1alpha_N
k59_866740_2	1121935.AQXX01000093_gene3417	2.09e-37	134.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,1XHJM@135619|Oceanospirillales	135619|Oceanospirillales	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	bkdA2	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_279118_1	177437.HRM2_40980	5.8e-92	296.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,43BJY@68525|delta/epsilon subdivisions,2WIWD@28221|Deltaproteobacteria,2MIG4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdnG-2	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_44025_2	1177928.TH2_03220	2.22e-12	68.2	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,2JQAW@204441|Rhodospirillales	204441|Rhodospirillales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_1102021_1	1123360.thalar_02885	5.51e-162	469.0	COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,2U068@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_161778_2	1121434.AULY01000010_gene2391	3.73e-06	50.8	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2WIRS@28221|Deltaproteobacteria,2M8QD@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_239982_1	1049564.TevJSym_ag00880	1.34e-130	387.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1JAJ9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Fumarate reductase flavoprotein C-term	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_514558_1	1197719.A464_4355	6.74e-05	49.7	COG0531@1|root,COG0531@2|Bacteria,1R5N5@1224|Proteobacteria,1RR4J@1236|Gammaproteobacteria,3ZKKZ@590|Salmonella	1236|Gammaproteobacteria	U	Amino acid permease	yjeM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
k59_200714_1	1122605.KB893630_gene4072	1.97e-11	66.2	COG2267@1|root,COG2267@2|Bacteria,4NHA9@976|Bacteroidetes,1IXNU@117747|Sphingobacteriia	976|Bacteroidetes	I	Ndr family	yfbB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_1023992_1	340099.Teth39_0487	2.09e-48	168.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,42EZ0@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,5.1.1.18	ko:K01775,ko:K18348	ko00473,ko01100,ko01502,ko02020,map00473,map01100,map01502,map02020	M00652	R00401	RC00285	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	-	-	-	Acyl_transf_3,Ala_racemase_C,Ala_racemase_N
k59_1102054_1	1250005.PHEL85_2863	3.29e-34	130.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1HX6Y@117743|Flavobacteriia,3VV9Y@52959|Polaribacter	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k59_83810_1	1535422.ND16A_1363	6.91e-41	151.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,2Q6Y5@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_5190_1	1124780.ANNU01000033_gene1326	2.75e-85	258.0	COG0388@1|root,COG0388@2|Bacteria,4NGH7@976|Bacteroidetes,47NQU@768503|Cytophagia	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
k59_200728_1	717231.Flexsi_0349	7.97e-63	204.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_632022_1	1333507.AUTQ01000261_gene3824	4.39e-94	289.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	iEcE24377_1341.EcE24377A_1810	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
k59_553460_1	1201293.AKXQ01000003_gene2560	3.29e-51	178.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_435781_1	177437.HRM2_01750	1.22e-124	369.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2MHPU@213118|Desulfobacterales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
k59_984961_1	1121405.dsmv_0105	1.39e-129	378.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WKEK@28221|Deltaproteobacteria,2MI5R@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_514629_1	795359.TOPB45_1372	1.4e-19	87.4	COG1180@1|root,COG1180@2|Bacteria,2GH3H@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_709971_1	1144275.COCOR_05413	1.03e-67	222.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria	1224|Proteobacteria	U	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_553489_1	1123269.NX02_24455	4.43e-52	175.0	COG2162@1|root,COG2162@2|Bacteria,1RDF3@1224|Proteobacteria,2U7QG@28211|Alphaproteobacteria,2K15A@204457|Sphingomonadales	204457|Sphingomonadales	Q	Belongs to the arylamine N-acetyltransferase family	nat	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
k59_984979_1	1163617.SCD_n01356	4.08e-32	124.0	COG1638@1|root,COG1638@2|Bacteria,1PN6J@1224|Proteobacteria,2VSNQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_279205_2	1121904.ARBP01000011_gene1466	1.15e-68	223.0	COG0845@1|root,COG0845@2|Bacteria,4NIDC@976|Bacteroidetes,47M9U@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_671072_1	1127673.GLIP_2806	1.17e-28	119.0	COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,1RP10@1236|Gammaproteobacteria,46A4N@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
k59_318286_1	1121405.dsmv_3532	2.94e-48	171.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42P6S@68525|delta/epsilon subdivisions,2WIWC@28221|Deltaproteobacteria,2MI1I@213118|Desulfobacterales	28221|Deltaproteobacteria	EQ	PFAM Hydantoinase oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
k59_83913_1	311403.Arad_3470	4.86e-54	170.0	COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,2U9T4@28211|Alphaproteobacteria,4BF8S@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
k59_592816_1	1121405.dsmv_1442	2.06e-80	266.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MI79@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_1180894_1	177437.HRM2_32880	4.95e-61	204.0	COG1624@1|root,COG1624@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,2MIQR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N,YbbR
k59_749362_1	1038860.AXAP01000059_gene1460	1.17e-95	288.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,3JSG0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	Belongs to the ABC transporter superfamily	MA20_22935	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_827860_1	743299.Acife_0609	2.3e-42	161.0	COG1640@1|root,COG3280@1|root,COG1640@2|Bacteria,COG3280@2|Bacteria,1QTVJ@1224|Proteobacteria,1RMJW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25,5.4.99.15	ko:K00705,ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R05196,R09995	RC00049	ko00000,ko00001,ko00002,ko01000	-	GH13,GH77	-	Glyco_hydro_77
k59_475203_1	1415778.JQMM01000001_gene2023	5.82e-54	178.0	COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,1J5V0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	yciK	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575	-	-	-	-	-	-	-	-	-	-	adh_short
k59_435882_1	177437.HRM2_16540	2.49e-14	71.6	COG0613@1|root,COG0613@2|Bacteria,1N68X@1224|Proteobacteria,42TYN@68525|delta/epsilon subdivisions,2WR34@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PHP-associated	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP_C
k59_435882_2	706587.Desti_2748	2.51e-12	63.5	COG4109@1|root,COG4109@2|Bacteria	2|Bacteria	K	DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
k59_1219785_1	306264.CUP0233	2.41e-12	69.3	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2YNAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Chorismate mutase prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_1219785_2	933262.AXAM01000043_gene1197	1.54e-16	78.6	COG1465@1|root,COG1465@2|Bacteria,1P42W@1224|Proteobacteria,42MQM@68525|delta/epsilon subdivisions,2WK5X@28221|Deltaproteobacteria,2MIRC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	3-dehydroquinate synthase (EC 4.6.1.3)	-	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
k59_749429_1	598467.BrE312_2991	4.96e-68	221.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_122937_1	391612.CY0110_20038	2.19e-17	80.9	2DRCR@1|root,33B8F@2|Bacteria,1G8D0@1117|Cyanobacteria,3KIA4@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function (DUF4174)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4174
k59_122937_2	1121456.ATVA01000011_gene1703	3.53e-20	87.4	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,42V21@68525|delta/epsilon subdivisions,2WRFF@28221|Deltaproteobacteria,2MCVG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
k59_710102_1	552467.XP_003195517.1	6.82e-30	121.0	COG0043@1|root,2QR5I@2759|Eukaryota,38EAD@33154|Opisthokonta,3NZD5@4751|Fungi	4751|Fungi	F	Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites	FDC1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009698,GO:0009803,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0018904,GO:0018958,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0033494,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046271,GO:0046281,GO:0046395,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615	4.1.1.102	ko:K20039	ko00940,map00940	-	R02952,R03367	RC00814	ko00000,ko00001,ko01000	-	-	-	UbiD
k59_592956_1	987059.RBXJA2T_01470	1.37e-73	236.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,2VK3E@28216|Betaproteobacteria,1KMZR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
k59_162003_1	1121957.ATVL01000009_gene876	4.43e-43	154.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,47J9W@768503|Cytophagia	976|Bacteroidetes	EG	PFAM RhaT l-rhamnose-proton symport 2	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
k59_279327_1	555778.Hneap_1961	2.44e-119	352.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_5361_1	1379698.RBG1_1C00001G0427	2.6e-55	188.0	COG2256@1|root,COG2256@2|Bacteria,2NNTG@2323|unclassified Bacteria	2|Bacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_514796_1	582899.Hden_3348	5.56e-104	304.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,3N6PK@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.9,3.1.3.15,4.2.1.19	ko:K00817,ko:K01089,ko:K01693	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03013,R03243,R03457	RC00006,RC00017,RC00888,RC00932	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	IGPD
k59_318406_2	1384056.N787_11210	9.67e-20	87.8	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,1X5Z8@135614|Xanthomonadales	135614|Xanthomonadales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_1181015_1	96561.Dole_0645	2.26e-22	101.0	COG0515@1|root,COG2199@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1R7HC@1224|Proteobacteria,43BQW@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	AAA_16,CHASE2,GAF,GAF_2,GGDEF,Hpt,PAS,Pkinase,Response_reg,SBP_bac_3
k59_84097_1	1121405.dsmv_1666	1.45e-55	196.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,2MMPS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_514823_1	933262.AXAM01000029_gene2729	1.94e-11	63.2	COG0655@1|root,COG0655@2|Bacteria,1RCDV@1224|Proteobacteria,42R2V@68525|delta/epsilon subdivisions,2WN0P@28221|Deltaproteobacteria,2MJJM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
k59_514823_2	56780.SYN_00833	5.18e-22	94.4	COG1305@1|root,COG1305@2|Bacteria,1Q1D3@1224|Proteobacteria,43772@68525|delta/epsilon subdivisions,2WSIA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_1024216_1	571166.KI421509_gene4326	2.49e-44	160.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_593007_1	759362.KVU_2280	2.41e-51	184.0	COG1674@1|root,COG3170@1|root,COG1674@2|Bacteria,COG3170@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_827972_1	338969.Rfer_2419	9.25e-35	130.0	COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,2VJW7@28216|Betaproteobacteria,4AAJH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
k59_671223_1	1260251.SPISAL_07670	7.22e-82	257.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1WX4H@135613|Chromatiales	135613|Chromatiales	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	OapA,Peptidase_M23
k59_553684_1	717785.HYPMC_2125	1.45e-114	344.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,3N6EJ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	ABC transporter	chvD	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
k59_84160_1	177437.HRM2_26230	7.22e-36	130.0	COG5421@1|root,COG5421@2|Bacteria,1R6MI@1224|Proteobacteria,42U8I@68525|delta/epsilon subdivisions,2WQCY@28221|Deltaproteobacteria,2MNWM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_788874_1	641107.CDLVIII_1103	2.12e-41	155.0	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,2494A@186801|Clostridia,36EAU@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_1063193_1	393595.ABO_0799	6.06e-36	129.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1XJBJ@135619|Oceanospirillales	135619|Oceanospirillales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_279432_1	1265505.ATUG01000001_gene4261	2.19e-59	202.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2MIS9@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_749575_1	1121405.dsmv_2870	7.16e-73	236.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MHXP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
k59_906246_1	236097.ADG881_3060	3.68e-25	105.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XHGC@135619|Oceanospirillales	135619|Oceanospirillales	CH	hydroxylase	ubiF	-	-	ko:K18800	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04987,R08768	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_475377_1	867845.KI911784_gene1605	1.16e-24	108.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	CARDB,DUF4091,FlgD_ig,Laminin_G_3,PKD,Peptidase_M43
k59_828022_1	9606.ENSP00000354876	2.4e-29	110.0	COG1622@1|root,KOG4767@2759|Eukaryota,38FF8@33154|Opisthokonta,3BEBX@33208|Metazoa,3D20G@33213|Bilateria,48627@7711|Chordata,4991G@7742|Vertebrata,3JCNC@40674|Mammalia,35H1B@314146|Euarchontoglires,4MP91@9443|Primates,4N090@9604|Hominidae	33208|Metazoa	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1	COX2	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006140,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006979,GO:0007275,GO:0007589,GO:0007595,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010310,GO:0010562,GO:0010726,GO:0010728,GO:0010729,GO:0010939,GO:0010940,GO:0010941,GO:0010942,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019219,GO:0019220,GO:0019222,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0030808,GO:0030810,GO:0030879,GO:0031090,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0045935,GO:0045937,GO:0045981,GO:0046034,GO:0046483,GO:0046903,GO:0048513,GO:0048518,GO:0048522,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0050794,GO:0050878,GO:0050896,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051194,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0080090,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1900371,GO:1900373,GO:1900542,GO:1900544,GO:1901135,GO:1901360,GO:1901564,GO:1902600,GO:1903426,GO:1903428,GO:1903578,GO:1903580,GO:2000377,GO:2000379,GO:2001169,GO:2001171	-	ko:K02261	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.11,3.D.4.7,3.D.4.8	-	-	COX2,COX2_TM
k59_1141392_1	227086.JGI_V11_21209	1.02e-14	78.2	COG0025@1|root,KOG1965@2759|Eukaryota	2759|Eukaryota	P	potassium:proton antiporter activity	SLC9C1	GO:0000302,GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005929,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0006928,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008324,GO:0009507,GO:0009526,GO:0009536,GO:0009628,GO:0009636,GO:0009651,GO:0009941,GO:0009987,GO:0010035,GO:0010351,GO:0010352,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019222,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030317,GO:0030641,GO:0031090,GO:0031253,GO:0031323,GO:0031514,GO:0031967,GO:0031975,GO:0034220,GO:0035725,GO:0040011,GO:0042221,GO:0042493,GO:0042542,GO:0042592,GO:0042995,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0046677,GO:0046873,GO:0048870,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051453,GO:0051674,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0060170,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0097722,GO:0098588,GO:0098590,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:0120025,GO:0120038,GO:0140115,GO:1901700,GO:1902600,GO:2000377	-	ko:K14726	-	-	-	-	ko00000,ko02000	2.A.36	-	-	Ion_trans,Na_H_Exchanger,cNMP_binding
k59_908063_1	1167006.UWK_01599	1.67e-56	190.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42P0U@68525|delta/epsilon subdivisions,2WJC6@28221|Deltaproteobacteria,2MIDV@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_477212_1	706587.Desti_2042	5.18e-101	309.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2WK1D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_1182810_1	1380380.JIAX01000012_gene470	4.91e-28	107.0	COG1028@1|root,COG1028@2|Bacteria,1RA3U@1224|Proteobacteria,2U640@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
k59_1245940_1	926560.KE387023_gene2248	9.09e-13	73.2	COG3552@1|root,COG3552@2|Bacteria,1WMMT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	VWA domain containing CoxE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
k59_107603_1	60711.ENSCSAP00000016435	2.94e-117	358.0	KOG2177@1|root,KOG2177@2759|Eukaryota,38F8A@33154|Opisthokonta,3BD9C@33208|Metazoa,3CRZC@33213|Bilateria,486MZ@7711|Chordata,494SK@7742|Vertebrata,3J4B3@40674|Mammalia,35G0C@314146|Euarchontoglires,4MIE8@9443|Primates,3683M@314294|Cercopithecoidea	33208|Metazoa	O	Tripartite motif containing 28	TRIM28	GO:0000003,GO:0000122,GO:0000228,GO:0000785,GO:0000790,GO:0000791,GO:0000792,GO:0001701,GO:0001837,GO:0001890,GO:0001892,GO:0002009,GO:0002376,GO:0003006,GO:0003401,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003712,GO:0003713,GO:0003714,GO:0003824,GO:0004672,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005667,GO:0005694,GO:0005719,GO:0005720,GO:0006139,GO:0006259,GO:0006281,GO:0006282,GO:0006304,GO:0006305,GO:0006306,GO:0006351,GO:0006352,GO:0006355,GO:0006357,GO:0006366,GO:0006367,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0006974,GO:0007154,GO:0007165,GO:0007264,GO:0007265,GO:0007275,GO:0007565,GO:0007566,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0016043,GO:0016070,GO:0016301,GO:0016310,GO:0016567,GO:0016740,GO:0016772,GO:0016773,GO:0016925,GO:0018130,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019787,GO:0019899,GO:0019904,GO:0022414,GO:0022607,GO:0023052,GO:0030154,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031625,GO:0031935,GO:0031937,GO:0031974,GO:0031981,GO:0032259,GO:0032386,GO:0032388,GO:0032446,GO:0032501,GO:0032502,GO:0032774,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033044,GO:0033157,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0035851,GO:0036211,GO:0040007,GO:0040012,GO:0040013,GO:0042306,GO:0042307,GO:0043009,GO:0043045,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043388,GO:0043412,GO:0043414,GO:0043900,GO:0043901,GO:0043903,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044389,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044703,GO:0044706,GO:0044728,GO:0044798,GO:0045069,GO:0045071,GO:0045087,GO:0045091,GO:0045739,GO:0045869,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046777,GO:0046822,GO:0046824,GO:0046872,GO:0046914,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048525,GO:0048568,GO:0048583,GO:0048584,GO:0048589,GO:0048598,GO:0048608,GO:0048729,GO:0048731,GO:0048762,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051052,GO:0051053,GO:0051054,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051222,GO:0051223,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0051704,GO:0051716,GO:0060026,GO:0060028,GO:0060255,GO:0060341,GO:0060429,GO:0060485,GO:0060560,GO:0060669,GO:0060968,GO:0061458,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070087,GO:0070201,GO:0070647,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090304,GO:0090308,GO:0090309,GO:0090316,GO:0090575,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1900180,GO:1900182,GO:1901360,GO:1901362,GO:1901363,GO:1901535,GO:1901536,GO:1901538,GO:1901564,GO:1901576,GO:1902186,GO:1902187,GO:1902275,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1903827,GO:1903829,GO:1903900,GO:1903901,GO:1904589,GO:1904591,GO:1904951,GO:1905269,GO:1990841,GO:2000112,GO:2000113,GO:2000653,GO:2001020,GO:2001022,GO:2001141,GO:2001252	2.3.2.27	ko:K08882,ko:K08883	-	-	-	-	ko00000,ko01000,ko01001,ko04121	-	-	-	PHD,zf-B_box,zf-RING_5
k59_615582_2	62928.azo1061	8.14e-05	50.4	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,2KVK6@206389|Rhodocyclales	206389|Rhodocyclales	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_927274_2	909663.KI867150_gene247	1.57e-72	231.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2MQ96@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_497571_1	756272.Plabr_1552	6.81e-22	99.4	COG1726@1|root,COG1726@2|Bacteria,2IWS5@203682|Planctomycetes	203682|Planctomycetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_927283_1	717231.Flexsi_0349	4e-62	201.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_65766_2	283942.IL0732	4.62e-40	144.0	COG2204@1|root,COG2204@2|Bacteria,1MWW5@1224|Proteobacteria,1RND4@1236|Gammaproteobacteria,2QFPQ@267893|Idiomarinaceae	1236|Gammaproteobacteria	K	Magnesium chelatase, subunit ChlI	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
k59_693609_1	27679.XP_010341745.1	2.15e-286	782.0	COG0087@1|root,KOG0746@2759|Eukaryota,38CDY@33154|Opisthokonta,3BANX@33208|Metazoa,3CYPX@33213|Bilateria,48733@7711|Chordata,48WII@7742|Vertebrata,3J889@40674|Mammalia,35CPG@314146|Euarchontoglires,4M77S@9443|Primates	33208|Metazoa	J	ribosomal protein	RPL3	GO:0000027,GO:0000184,GO:0000956,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0016043,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0031974,GO:0031981,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0050789,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0070727,GO:0070925,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071826,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576	-	ko:K02925	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_183466_1	1158294.JOMI01000004_gene3318	8.27e-29	119.0	COG0364@1|root,COG0364@2|Bacteria,4NE59@976|Bacteroidetes,2FNER@200643|Bacteroidia	976|Bacteroidetes	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_615675_1	1122604.JONR01000020_gene487	2.85e-19	85.5	COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,1X6ZM@135614|Xanthomonadales	135614|Xanthomonadales	NT	Two component signalling adaptor domain	-	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
k59_497597_1	289376.THEYE_A0734	4.25e-45	150.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_497597_2	883.DvMF_1772	1.35e-07	51.2	COG2204@1|root,COG2204@2|Bacteria,1QUMA@1224|Proteobacteria,43BKZ@68525|delta/epsilon subdivisions,2X6Z5@28221|Deltaproteobacteria,2MH8W@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_183480_1	35841.BT1A1_0851	6.55e-16	83.6	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,4HDFR@91061|Bacilli	91061|Bacilli	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_615693_1	1415778.JQMM01000001_gene1029	1.3e-42	149.0	COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,1RMXK@1236|Gammaproteobacteria,1J9B9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	transport system, ATPase component	modF	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.34	ko:K02013,ko:K05776	ko02010,map02010	M00189,M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
k59_425292_1	267608.RSp0109	3.6e-112	334.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,1K1U1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_225839_1	472759.Nhal_0926	1.61e-54	178.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1WY0M@135613|Chromatiales	135613|Chromatiales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
k59_458202_1	675816.VIA_000318	5.24e-05	45.1	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1XVI5@135623|Vibrionales	135623|Vibrionales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_575749_1	765914.ThisiDRAFT_1467	3.3e-106	324.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1WVW2@135613|Chromatiales	135613|Chromatiales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_653486_1	1121403.AUCV01000008_gene1617	1.4e-61	202.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,2MIBH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_183493_1	266265.Bxe_C0666	1.44e-33	131.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,1K02G@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_575756_1	637389.Acaty_m0165	2.93e-11	68.6	COG3677@1|root,COG3677@2|Bacteria,1R3ZS@1224|Proteobacteria,1SZQS@1236|Gammaproteobacteria,2NDTK@225057|Acidithiobacillales	1236|Gammaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_381323_1	1304275.C41B8_05288	6.39e-43	153.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_381323_2	340177.Cag_1793	0.000178	46.6	COG0363@1|root,COG0363@2|Bacteria,1FF3Q@1090|Chlorobi	1090|Chlorobi	G	TIGRFAM 6-phosphogluconolactonase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
k59_65834_1	118797.XP_007463526.1	2.89e-52	183.0	KOG2242@1|root,KOG2242@2759|Eukaryota,38FNX@33154|Opisthokonta,3BD0H@33208|Metazoa,3CRCQ@33213|Bilateria,481JN@7711|Chordata,495WA@7742|Vertebrata,3J5FP@40674|Mammalia,4IY08@91561|Cetartiodactyla	33208|Metazoa	A	heterogeneous nuclear ribonucleoprotein U	HNRNPU	GO:0000122,GO:0000166,GO:0000228,GO:0000375,GO:0000377,GO:0000381,GO:0000398,GO:0000775,GO:0000776,GO:0000803,GO:0000976,GO:0000977,GO:0000978,GO:0000987,GO:0000993,GO:0001012,GO:0001067,GO:0001085,GO:0001091,GO:0001097,GO:0001098,GO:0001099,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003697,GO:0003712,GO:0003714,GO:0003723,GO:0003725,GO:0003727,GO:0003729,GO:0003730,GO:0003779,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005694,GO:0005697,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005856,GO:0005874,GO:0005876,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006397,GO:0006403,GO:0006725,GO:0006807,GO:0007088,GO:0007275,GO:0007346,GO:0007507,GO:0007549,GO:0007623,GO:0008092,GO:0008104,GO:0008134,GO:0008143,GO:0008144,GO:0008150,GO:0008152,GO:0008187,GO:0008284,GO:0008380,GO:0009048,GO:0009410,GO:0009719,GO:0009725,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009986,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010638,GO:0010639,GO:0010911,GO:0010912,GO:0014070,GO:0014706,GO:0015630,GO:0016070,GO:0016071,GO:0016363,GO:0016604,GO:0016607,GO:0017069,GO:0017076,GO:0017130,GO:0019219,GO:0019220,GO:0019222,GO:0019899,GO:0030154,GO:0030496,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031490,GO:0031960,GO:0031974,GO:0031981,GO:0032204,GO:0032205,GO:0032210,GO:0032211,GO:0032501,GO:0032502,GO:0032507,GO:0032553,GO:0032555,GO:0032559,GO:0032781,GO:0032784,GO:0032785,GO:0032870,GO:0032879,GO:0032886,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0033365,GO:0033673,GO:0033993,GO:0034046,GO:0034097,GO:0034243,GO:0034244,GO:0034399,GO:0034504,GO:0034613,GO:0034641,GO:0035051,GO:0035372,GO:0035639,GO:0035690,GO:0035770,GO:0036002,GO:0036094,GO:0036464,GO:0040029,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0042493,GO:0042692,GO:0042802,GO:0043021,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043462,GO:0043484,GO:0043487,GO:0043488,GO:0043489,GO:0043549,GO:0043565,GO:0044087,GO:0044092,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044380,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0044877,GO:0045185,GO:0045595,GO:0045596,GO:0045597,GO:0045598,GO:0045600,GO:0045787,GO:0045840,GO:0045892,GO:0045893,GO:0045931,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0046483,GO:0048024,GO:0048255,GO:0048468,GO:0048511,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0050684,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051233,GO:0051235,GO:0051252,GO:0051253,GO:0051254,GO:0051336,GO:0051338,GO:0051345,GO:0051348,GO:0051384,GO:0051457,GO:0051493,GO:0051641,GO:0051651,GO:0051716,GO:0051726,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0051987,GO:0051988,GO:0055001,GO:0055002,GO:0055006,GO:0055007,GO:0055013,GO:0060236,GO:0060255,GO:0060341,GO:0060537,GO:0061013,GO:0061061,GO:0062033,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070034,GO:0070063,GO:0070507,GO:0070717,GO:0070727,GO:0070887,GO:0070934,GO:0070937,GO:0071013,GO:0071310,GO:0071345,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0072091,GO:0072359,GO:0072595,GO:0072686,GO:0072698,GO:0080090,GO:0090068,GO:0090169,GO:0090224,GO:0090235,GO:0090304,GO:0090335,GO:0090336,GO:0097159,GO:0097327,GO:0097367,GO:0098577,GO:0098687,GO:0099080,GO:0099081,GO:0099122,GO:0099512,GO:0099513,GO:0140110,GO:1901265,GO:1901360,GO:1901363,GO:1901654,GO:1901655,GO:1901673,GO:1901700,GO:1901701,GO:1902115,GO:1902275,GO:1902369,GO:1902373,GO:1902423,GO:1902425,GO:1902494,GO:1902679,GO:1902680,GO:1902889,GO:1903311,GO:1903312,GO:1903506,GO:1903507,GO:1903508,GO:1904356,GO:1904357,GO:1990023,GO:1990280,GO:1990498,GO:1990823,GO:1990830,GO:1990837,GO:1990841,GO:1990845,GO:1990904,GO:2000112,GO:2000113,GO:2000278,GO:2000279,GO:2000371,GO:2000373,GO:2000648,GO:2000736,GO:2000737,GO:2001141,GO:2001251,GO:2001252	-	ko:K12888,ko:K15047,ko:K15698	ko03040,ko05164,map03040,map05164	-	-	-	ko00000,ko00001,ko03041,ko04121	-	-	-	AAA_33,SAP,SPRY
k59_1124587_1	498761.HM1_1275	1.05e-41	145.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
k59_771664_1	383407.XOC_4261	1.36e-40	149.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1X4KT@135614|Xanthomonadales	135614|Xanthomonadales	O	Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_927359_1	566466.NOR53_2737	5.25e-149	431.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RNJH@1236|Gammaproteobacteria,1J7V6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1960 Acyl-CoA dehydrogenases	bbsG	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_107789_1	1089552.KI911559_gene3349	2.5e-50	166.0	2B2JS@1|root,31V51@2|Bacteria,1QT11@1224|Proteobacteria,2VAWF@28211|Alphaproteobacteria,2JY2A@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
k59_540396_1	391595.RLO149_c022170	4.6e-17	83.2	2CDFF@1|root,31AC8@2|Bacteria,1Q5BT@1224|Proteobacteria,2VBQG@28211|Alphaproteobacteria,2P535@2433|Roseobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_107792_1	118797.XP_007465685.1	1.54e-123	366.0	COG0056@1|root,KOG1353@2759|Eukaryota,38ERH@33154|Opisthokonta,3BCEE@33208|Metazoa,3CU79@33213|Bilateria,489CP@7711|Chordata,497ZQ@7742|Vertebrata,3J34Z@40674|Mammalia,4J1PP@91561|Cetartiodactyla	33208|Metazoa	C	ATP synthase, H transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	ATP5A1	GO:0000166,GO:0000275,GO:0001936,GO:0001937,GO:0003674,GO:0003824,GO:0005102,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0005759,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006839,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0008144,GO:0008150,GO:0008152,GO:0008285,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0010594,GO:0010595,GO:0010632,GO:0010634,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016043,GO:0016310,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0019866,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030334,GO:0030335,GO:0030554,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040012,GO:0040017,GO:0042127,GO:0042287,GO:0042288,GO:0042407,GO:0042623,GO:0042625,GO:0042626,GO:0042776,GO:0043167,GO:0043168,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043492,GO:0043531,GO:0043532,GO:0043535,GO:0043536,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044769,GO:0045121,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0046907,GO:0046933,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050678,GO:0050680,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051270,GO:0051272,GO:0051641,GO:0051649,GO:0055085,GO:0055086,GO:0061024,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0097159,GO:0097367,GO:0098589,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098805,GO:0098857,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902600,GO:1990542,GO:2000145,GO:2000147	-	ko:K02132	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_1163646_1	1397528.Q671_16430	5.8e-127	369.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1XHH6@135619|Oceanospirillales	135619|Oceanospirillales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroF-1	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
k59_809548_1	589924.Ferp_0343	1.73e-22	99.4	COG4012@1|root,arCOG04365@2157|Archaea,2XUWU@28890|Euryarchaeota,245PK@183980|Archaeoglobi	183980|Archaeoglobi	S	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
k59_927388_1	1469245.JFBG01000030_gene1547	5.28e-51	174.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,1WXT8@135613|Chromatiales	135613|Chromatiales	S	PFAM Uncharacterised protein family UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_107823_1	1144275.COCOR_01446	1.78e-62	211.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MRU@68525|delta/epsilon subdivisions,2WIQX@28221|Deltaproteobacteria,2YZUW@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_183538_1	565045.NOR51B_1598	1.03e-85	263.0	COG4313@1|root,COG4313@2|Bacteria,1MWCX@1224|Proteobacteria,1S4A1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG4313 Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k59_341097_1	397945.Aave_2936	1.22e-45	149.0	COG2963@1|root,COG2963@2|Bacteria,1N1AA@1224|Proteobacteria,2VU5U@28216|Betaproteobacteria,4AI0D@80864|Comamonadaceae	28216|Betaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_341097_2	349163.Acry_1286	2.32e-44	150.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2TU72@28211|Alphaproteobacteria,2JQ3I@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k59_1047768_1	1469245.JFBG01000019_gene1125	3.81e-147	448.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1WXI8@135613|Chromatiales	135613|Chromatiales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_1203305_1	1150600.ADIARSV_2279	9.92e-20	94.0	COG0642@1|root,COG3292@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1IRJZ@117747|Sphingobacteriia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y
k59_425425_1	1232437.KL662016_gene1039	2.7e-94	290.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2MIPI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM carboxyl transferase	-	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_381441_1	335543.Sfum_1735	4.93e-09	53.1	2EBS7@1|root,335S2@2|Bacteria,1NBWR@1224|Proteobacteria,42WCA@68525|delta/epsilon subdivisions,2WRUH@28221|Deltaproteobacteria,2MSBP@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1246107_1	1121405.dsmv_2083	2.53e-20	90.5	COG1597@1|root,COG1597@2|Bacteria,1RIZ6@1224|Proteobacteria	1224|Proteobacteria	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
k59_381461_1	391616.OA238_c14660	4.99e-59	192.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,2U0PH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
k59_1124675_1	1123368.AUIS01000019_gene1219	9.78e-66	223.0	COG3290@1|root,COG5001@1|root,COG3290@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,EAL,GGDEF,PAS,PAS_4
k59_540510_1	2880.D7G0R3	7.75e-60	201.0	COG1012@1|root,KOG2451@2759|Eukaryota	2759|Eukaryota	C	succinate-semialdehyde dehydrogenase (NAD+) activity	-	GO:0003674,GO:0003824,GO:0003842,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006536,GO:0006560,GO:0006562,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009507,GO:0009536,GO:0009628,GO:0009651,GO:0009987,GO:0010133,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019752,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0055114,GO:0071704,GO:0072593,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_653600_1	113395.AXAI01000006_gene1703	5.22e-23	104.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2TT8A@28211|Alphaproteobacteria,3JUPJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	NU	Bacterial type II/III secretion system short domain	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_107918_1	1077972.ARGLB_035_00140	4.94e-25	102.0	COG3621@1|root,COG3621@2|Bacteria,2I97F@201174|Actinobacteria,1WAYR@1268|Micrococcaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_302436_1	933262.AXAM01000077_gene1704	3.69e-95	295.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,43BR1@68525|delta/epsilon subdivisions,2WIIS@28221|Deltaproteobacteria,2MIQ9@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
k59_1084587_1	335543.Sfum_1596	7.09e-18	82.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2MRQY@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_1084587_2	667014.Thein_0177	1.27e-14	73.6	COG1648@1|root,COG1648@2|Bacteria,2GH09@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Sirohaem biosynthesis protein central	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
k59_497765_1	228410.NE1785	6.82e-43	144.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,3738M@32003|Nitrosomonadales	28216|Betaproteobacteria	T	low molecular weight	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_615917_1	396595.TK90_0713	6.48e-88	270.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1WWH3@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
k59_107952_1	1123070.KB899252_gene856	4.68e-35	135.0	COG1538@1|root,COG1538@2|Bacteria,46US3@74201|Verrucomicrobia,2IUAN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_342276_2	1484460.JSWG01000004_gene2575	2.78e-21	90.5	COG1595@1|root,COG1595@2|Bacteria,4NTAA@976|Bacteroidetes,1I44G@117743|Flavobacteriia	976|Bacteroidetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
k59_184503_1	880072.Desac_0001	9.71e-34	130.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,2MR3D@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_1164861_1	1279017.AQYJ01000026_gene379	2.7e-91	286.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RR0R@1236|Gammaproteobacteria,469YC@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_303437_1	335543.Sfum_0125	9.16e-22	99.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,2MRYH@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
k59_145389_1	457415.HMPREF1006_00701	4.66e-35	139.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	lapB	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
k59_810642_1	1121405.dsmv_3464	4.99e-40	153.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2MIEU@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
k59_226988_2	566466.NOR53_1080	2.34e-09	60.1	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,1S1KW@1236|Gammaproteobacteria,1J5NA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
k59_109358_1	335543.Sfum_1977	3.74e-44	164.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_1085632_1	1441629.PCH70_27840	0.000134	49.3	COG0500@1|root,COG2226@2|Bacteria,1MW7J@1224|Proteobacteria,1T2EV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
k59_184529_1	768671.ThimaDRAFT_1409	0.000418	42.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1WWG7@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k59_184529_2	640081.Dsui_3260	1.06e-23	100.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,2KV9E@206389|Rhodocyclales	206389|Rhodocyclales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_654679_1	1174528.JH992893_gene5951	1.36e-21	98.6	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIN@1189|Stigonemataceae	1117|Cyanobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,Methyltransf_25,PP-binding,Thioesterase
k59_184543_1	667014.Thein_0206	1.05e-79	254.0	COG2262@1|root,COG2262@2|Bacteria,2GH9H@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_654693_1	1123400.KB904758_gene2390	2.11e-62	202.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,45ZQ9@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_303468_1	671143.DAMO_3064	3.77e-50	171.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	yghO	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	-
k59_303468_2	1304275.C41B8_04666	1.04e-05	48.1	COG0746@1|root,COG0746@2|Bacteria,1QWF1@1224|Proteobacteria,1T603@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
k59_1125849_1	96561.Dole_2547	3.36e-20	94.7	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria,2MI3Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_890756_1	713587.THITH_07390	1.24e-90	293.0	COG0457@1|root,COG0457@2|Bacteria,1QZTW@1224|Proteobacteria,1T54Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
k59_577303_1	485916.Dtox_0172	1.74e-23	103.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,2610M@186807|Peptococcaceae	186801|Clostridia	C	iron hydrogenase, small subunit	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Fer4_9,NADH-G_4Fe-4S_3
k59_459567_1	1121013.P873_07800	2.33e-42	156.0	COG1461@1|root,COG1461@2|Bacteria,1NKAM@1224|Proteobacteria,1SHAC@1236|Gammaproteobacteria,1X3IB@135614|Xanthomonadales	135614|Xanthomonadales	S	Dak2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
k59_28164_1	1163617.SCD_n00222	2.07e-60	200.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,2VI6J@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Urea ABC transporter, urea binding protein	-	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
k59_1247103_1	27679.XP_010345651.1	1.27e-233	646.0	COG0126@1|root,KOG1367@2759|Eukaryota,38EF9@33154|Opisthokonta,3BE59@33208|Metazoa,3CT3V@33213|Bilateria,481D5@7711|Chordata,48WCW@7742|Vertebrata,3J4KQ@40674|Mammalia,35C3S@314146|Euarchontoglires,4MKKX@9443|Primates	33208|Metazoa	G	phosphoglycerate kinase activity	PGK1	GO:0000166,GO:0000768,GO:0001666,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006508,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006949,GO:0006950,GO:0007154,GO:0007267,GO:0007268,GO:0007520,GO:0007525,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009628,GO:0009653,GO:0009888,GO:0009987,GO:0010467,GO:0014902,GO:0015036,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016485,GO:0016491,GO:0016525,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019725,GO:0019752,GO:0022603,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030154,GO:0030554,GO:0030855,GO:0031430,GO:0031638,GO:0031639,GO:0031672,GO:0031674,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035639,GO:0036094,GO:0036293,GO:0036294,GO:0042221,GO:0042592,GO:0042692,GO:0042866,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043436,GO:0043531,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044449,GO:0044464,GO:0045121,GO:0045765,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046716,GO:0046939,GO:0047134,GO:0048519,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051146,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051604,GO:0051716,GO:0055086,GO:0055114,GO:0060249,GO:0060429,GO:0061061,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0065007,GO:0065008,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:0098589,GO:0098805,GO:0098857,GO:0098916,GO:0099080,GO:0099081,GO:0099512,GO:0099536,GO:0099537,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901342,GO:1901343,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2000026,GO:2000181	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
k59_1067203_1	381666.H16_B1511	2.33e-23	93.6	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,2VRYW@28216|Betaproteobacteria,1K931@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_1067203_2	981336.F944_00101	1.76e-11	63.9	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,3NJ5K@468|Moraxellaceae	1236|Gammaproteobacteria	Q	ATPases associated with a variety of cellular activities	mlaF	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0008144,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_322742_1	880072.Desac_0096	4.58e-37	142.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_8,PAS_9,Response_reg,SBP_bac_3
k59_48800_1	1269813.ATUL01000022_gene778	0.000126	49.7	COG2199@1|root,COG3706@2|Bacteria,1NAG0@1224|Proteobacteria,1RPKX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	ko:K19707	-	-	-	-	ko00000,ko03021	-	-	-	7TMR-DISM_7TM,GAF,GGDEF,PAS_9,Response_reg,dCache_3
k59_205160_2	1121374.KB891575_gene1632	2.27e-47	156.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S4GX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_1029146_1	10029.XP_007627869.1	6.67e-05	43.5	KOG3158@1|root,KOG3158@2759|Eukaryota,3A1J4@33154|Opisthokonta,3BAQK@33208|Metazoa,3CYPV@33213|Bilateria,48365@7711|Chordata,48ZDK@7742|Vertebrata,3JB9I@40674|Mammalia,35ESA@314146|Euarchontoglires,4Q5M1@9989|Rodentia	33208|Metazoa	K	Prostaglandin E synthase	PTGES3	GO:0000271,GO:0000723,GO:0000781,GO:0001516,GO:0001676,GO:0002039,GO:0003008,GO:0003674,GO:0003720,GO:0003824,GO:0003964,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005697,GO:0005737,GO:0005829,GO:0005856,GO:0005884,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006082,GO:0006091,GO:0006112,GO:0006139,GO:0006259,GO:0006278,GO:0006457,GO:0006458,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0006725,GO:0006805,GO:0006807,GO:0006996,GO:0007004,GO:0007154,GO:0007165,GO:0007275,GO:0007600,GO:0008150,GO:0008152,GO:0008283,GO:0008610,GO:0009058,GO:0009059,GO:0009250,GO:0009410,GO:0009719,GO:0009725,GO:0009755,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010604,GO:0010628,GO:0010833,GO:0010941,GO:0014070,GO:0015629,GO:0015980,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016853,GO:0016860,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019233,GO:0019369,GO:0019371,GO:0019438,GO:0019752,GO:0019899,GO:0022607,GO:0022613,GO:0022618,GO:0023052,GO:0030323,GO:0030324,GO:0030518,GO:0030522,GO:0031072,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031647,GO:0031958,GO:0031974,GO:0031981,GO:0032200,GO:0032501,GO:0032502,GO:0032787,GO:0032870,GO:0032991,GO:0033559,GO:0033692,GO:0033993,GO:0034061,GO:0034622,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0035295,GO:0036477,GO:0042221,GO:0042325,GO:0042327,GO:0042592,GO:0042921,GO:0042995,GO:0043005,GO:0043025,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043401,GO:0043436,GO:0043588,GO:0043933,GO:0044042,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0045935,GO:0045937,GO:0046394,GO:0046456,GO:0046457,GO:0046483,GO:0048286,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048731,GO:0048856,GO:0050220,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050877,GO:0050896,GO:0051052,GO:0051054,GO:0051082,GO:0051084,GO:0051085,GO:0051131,GO:0051171,GO:0051173,GO:0051174,GO:0051276,GO:0051338,GO:0051347,GO:0051716,GO:0051879,GO:0051972,GO:0051973,GO:0055114,GO:0060249,GO:0060255,GO:0060430,GO:0060541,GO:0060548,GO:0061077,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070182,GO:0070887,GO:0071310,GO:0071383,GO:0071396,GO:0071407,GO:0071466,GO:0071495,GO:0071704,GO:0071826,GO:0071840,GO:0071897,GO:0072330,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097458,GO:0098687,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0101031,GO:0120025,GO:0140097,GO:1900034,GO:1901360,GO:1901362,GO:1901568,GO:1901570,GO:1901576,GO:1905323,GO:1990904,GO:2000112,GO:2000278,GO:2000573	5.3.99.3	ko:K15730	ko00590,ko01100,map00590,map01100	-	R02265	RC00672	ko00000,ko00001,ko01000	-	-	-	CS
k59_362499_1	933262.AXAM01000046_gene129	2.25e-100	301.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2MHVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_283614_1	1552758.NC00_05270	1.52e-52	178.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,1RP40@1236|Gammaproteobacteria,1X9U3@135614|Xanthomonadales	135614|Xanthomonadales	G	Gluconolactonase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
k59_166236_1	498211.CJA_3793	9.4e-17	74.7	COG2963@1|root,COG2963@2|Bacteria,1RHBZ@1224|Proteobacteria,1S69Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	GO:0005575,GO:0005623,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0032196,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0046483,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_166236_2	598467.BrE312_4058	1.12e-69	219.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	insF	GO:0008150,GO:0009987,GO:0032196	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
k59_871205_1	1125863.JAFN01000001_gene163	1.79e-84	269.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_715041_1	1349767.GJA_2635	1.26e-51	173.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,2VJEB@28216|Betaproteobacteria,476IH@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	AAA domain	yveL	-	2.7.10.1	ko:K08252,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,GNVR,Wzz
k59_362523_1	1235793.C809_00238	3.39e-08	59.7	COG1309@1|root,COG1309@2|Bacteria,1V1QA@1239|Firmicutes,249CB@186801|Clostridia,27JWN@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1029221_1	391616.OA238_c11160	3.99e-21	92.4	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	MA20_29420	-	6.2.1.48	ko:K00666,ko:K02182	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_440523_1	706587.Desti_1887	1.94e-88	276.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.3.5.4,1.4.3.16	ko:K00244,ko:K00278	ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00115,M00150,M00173	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_479667_2	2340.JV46_26720	1.17e-105	322.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,1RMC3@1236|Gammaproteobacteria,1JARP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Nickel-dependent hydrogenase	hydB	-	1.12.5.1,1.12.99.6	ko:K05922,ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_557974_1	644282.Deba_1628	1.91e-55	191.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_675575_1	1122182.KB903825_gene750	1.3e-22	101.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8,SLH,fn3
k59_753837_1	1265505.ATUG01000002_gene1129	1.91e-21	95.1	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2MI0C@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
k59_753837_2	379066.GAU_2382	8.54e-118	346.0	COG1013@1|root,COG1013@2|Bacteria,1ZSWT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_283695_1	857087.Metme_2565	5.63e-31	123.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,1S27X@1236|Gammaproteobacteria,1XF6U@135618|Methylococcales	135618|Methylococcales	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_283695_2	323261.Noc_0327	1.05e-09	59.3	COG0526@1|root,COG0526@2|Bacteria,1MZ9B@1224|Proteobacteria,1SBA1@1236|Gammaproteobacteria,1X1F2@135613|Chromatiales	135613|Chromatiales	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_362577_1	395495.Lcho_3892	1.46e-24	106.0	COG3391@1|root,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,2W09X@28216|Betaproteobacteria,1KMW8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
k59_401750_1	926692.AZYG01000050_gene174	2.31e-45	148.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,24NM6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_166301_1	247639.MGP2080_08771	2.73e-112	334.0	COG3391@1|root,COG3391@2|Bacteria,1MXDX@1224|Proteobacteria,1S012@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
k59_675587_2	326442.PSHAa1313	2.22e-103	326.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,2Q08T@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	I	Phospholipase D Active site motif	-	-	-	ko:K06131,ko:K06132	ko00564,ko01100,map00564,map01100	-	R07390,R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_989836_1	1255043.TVNIR_3827	4.2e-57	190.0	COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RPH5@1236|Gammaproteobacteria,1WXHI@135613|Chromatiales	135613|Chromatiales	C	Oxidoreductase FAD-binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
k59_283712_1	1121377.KB906402_gene3232	3.01e-24	102.0	COG0457@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
k59_88652_1	396588.Tgr7_1014	3.13e-105	336.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,1WW9S@135613|Chromatiales	135613|Chromatiales	E	Bacterial transglutaminase-like N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
k59_715149_1	1411123.JQNH01000001_gene1491	1.33e-96	294.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2TSKS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
k59_792987_1	1121878.AUGL01000009_gene3377	2.5e-29	115.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RZSX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_322877_1	879212.DespoDRAFT_01537	1.45e-13	70.1	COG0711@1|root,COG0711@2|Bacteria,1NA9K@1224|Proteobacteria,42VN2@68525|delta/epsilon subdivisions,2WR8C@28221|Deltaproteobacteria,2MKBA@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpX	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
k59_1224771_1	4558.Sb02g025980.1	1.21e-29	116.0	COG0421@1|root,KOG1562@2759|Eukaryota,37P2N@33090|Viridiplantae,3G8WD@35493|Streptophyta,3KUAR@4447|Liliopsida,3I5DD@38820|Poales	35493|Streptophyta	H	Spermidine synthase tetramerisation domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008150,GO:0009888,GO:0009914,GO:0009926,GO:0009987,GO:0010087,GO:0010089,GO:0010487,GO:0010817,GO:0016740,GO:0016765,GO:0016768,GO:0030154,GO:0032502,GO:0044424,GO:0044464,GO:0048759,GO:0048856,GO:0048869,GO:0051179,GO:0051234,GO:0060918,GO:0065007,GO:0065008,GO:1905177	2.5.1.79	ko:K18787	-	-	-	-	ko00000,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
k59_1224771_2	313606.M23134_04873	5.55e-32	116.0	COG1586@1|root,COG1586@2|Bacteria,4NVRA@976|Bacteroidetes,47RGR@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speD	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
k59_715165_1	398767.Glov_2183	5.16e-57	187.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,43U3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_597480_1	999141.GME_10031	1.54e-24	103.0	COG3650@1|root,COG3650@2|Bacteria,1N019@1224|Proteobacteria,1SBAD@1236|Gammaproteobacteria,1XQ93@135619|Oceanospirillales	135619|Oceanospirillales	S	Membrane-bound lysozyme-inhibitor of c-type lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	MliC
k59_675613_1	243231.GSU0384	9.65e-32	117.0	COG1633@1|root,COG1633@2|Bacteria,1NVAF@1224|Proteobacteria,42ZHS@68525|delta/epsilon subdivisions,2WV0C@28221|Deltaproteobacteria,43UQE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
k59_910386_1	9402.XP_006918357.1	5.5e-189	531.0	COG0708@1|root,KOG1294@2759|Eukaryota,38BCR@33154|Opisthokonta,3B9IS@33208|Metazoa,3CT5V@33213|Bilateria,482NT@7711|Chordata,49749@7742|Vertebrata,3JDZW@40674|Mammalia,4KZNP@9397|Chiroptera	33208|Metazoa	L	Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'- deoxyribose phosphate and 3'-hydroxyl ends	APEX1	GO:0000228,GO:0000302,GO:0000723,GO:0000781,GO:0000784,GO:0001947,GO:0002009,GO:0002119,GO:0002164,GO:0003007,GO:0003008,GO:0003013,GO:0003015,GO:0003143,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003690,GO:0003691,GO:0003712,GO:0003713,GO:0003714,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004521,GO:0004523,GO:0004527,GO:0004528,GO:0004529,GO:0004536,GO:0004540,GO:0004844,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005667,GO:0005694,GO:0005730,GO:0005737,GO:0005739,GO:0005783,GO:0005813,GO:0005815,GO:0005840,GO:0005856,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006286,GO:0006304,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0006996,GO:0007275,GO:0007346,GO:0007368,GO:0007389,GO:0007507,GO:0007568,GO:0008015,GO:0008081,GO:0008134,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009791,GO:0009792,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010941,GO:0012505,GO:0014070,GO:0014074,GO:0014910,GO:0014912,GO:0015630,GO:0016043,GO:0016070,GO:0016311,GO:0016491,GO:0016604,GO:0016607,GO:0016787,GO:0016788,GO:0016796,GO:0016798,GO:0016799,GO:0016888,GO:0016890,GO:0016891,GO:0016893,GO:0016895,GO:0019104,GO:0019219,GO:0019222,GO:0019725,GO:0030334,GO:0030336,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031490,GO:0031974,GO:0031981,GO:0032200,GO:0032501,GO:0032502,GO:0032870,GO:0032879,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035050,GO:0035239,GO:0035295,GO:0035510,GO:0035690,GO:0040012,GO:0040013,GO:0042162,GO:0042221,GO:0042493,GO:0042542,GO:0042578,GO:0042592,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043247,GO:0043412,GO:0043434,GO:0043487,GO:0043488,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044728,GO:0044877,GO:0045454,GO:0045787,GO:0045931,GO:0045934,GO:0045935,GO:0046483,GO:0046677,GO:0046683,GO:0046872,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048568,GO:0048598,GO:0048729,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051059,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051270,GO:0051271,GO:0051276,GO:0051591,GO:0051716,GO:0051726,GO:0052720,GO:0055114,GO:0060047,GO:0060249,GO:0060255,GO:0060429,GO:0060548,GO:0060562,GO:0061013,GO:0061371,GO:0065007,GO:0065008,GO:0070013,GO:0070301,GO:0070887,GO:0070988,GO:0071236,GO:0071310,GO:0071320,GO:0071375,GO:0071407,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0080111,GO:0090068,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0097237,GO:0097506,GO:0097698,GO:0098501,GO:0098502,GO:0098687,GO:0140097,GO:0140098,GO:0140110,GO:1900087,GO:1901360,GO:1901363,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902679,GO:1902680,GO:1902806,GO:1902808,GO:1903311,GO:1903506,GO:1903507,GO:1903508,GO:1990904,GO:2000045,GO:2000145,GO:2000146,GO:2001141	4.2.99.18	ko:K10771	ko03410,map03410	M00296	-	-	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_128861_2	1144312.PMI09_03888	1.47e-09	60.8	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,2UA4N@28211|Alphaproteobacteria,4BFS2@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	-acetyltransferase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
k59_1068954_1	1034943.BN1094_02625	7.49e-113	336.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1JDF8@118969|Legionellales	118969|Legionellales	C	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	ICL
k59_755572_1	439235.Dalk_0615	5.56e-43	152.0	28MQN@1|root,2ZAZG@2|Bacteria,1MVVQ@1224|Proteobacteria,42MMM@68525|delta/epsilon subdivisions,2WKA1@28221|Deltaproteobacteria,2MHKP@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_873080_1	439235.Dalk_2054	1.56e-77	239.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42N5A@68525|delta/epsilon subdivisions,2WKKI@28221|Deltaproteobacteria,2MIZW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AAA ATPase domain	clpB1	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
k59_755577_1	522306.CAP2UW1_1298	4.4e-40	147.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria,1KQHV@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
k59_207070_1	756067.MicvaDRAFT_0333	2.83e-21	97.8	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
k59_1108490_1	51337.XP_004653444.1	6.14e-101	304.0	KOG0118@1|root,KOG0118@2759|Eukaryota,39X6S@33154|Opisthokonta,3B9VW@33208|Metazoa,3CZBF@33213|Bilateria,4817E@7711|Chordata,48WMS@7742|Vertebrata,3J794@40674|Mammalia,35N87@314146|Euarchontoglires,4PZJC@9989|Rodentia	33208|Metazoa	A	Heterogeneous nuclear ribonucleoprotein D-like	HNRNPDL	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0008143,GO:0008150,GO:0008152,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0016070,GO:0016071,GO:0019221,GO:0019222,GO:0023052,GO:0031974,GO:0031981,GO:0032991,GO:0034046,GO:0034097,GO:0034641,GO:0035722,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060255,GO:0065007,GO:0070013,GO:0070671,GO:0070717,GO:0070887,GO:0071310,GO:0071345,GO:0071349,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904	-	ko:K13044	-	-	-	-	ko00000,ko03041	-	-	-	RRM_1
k59_1186977_1	1390370.O203_23395	5.91e-17	85.1	COG2207@1|root,COG2207@2|Bacteria,1Q3UX@1224|Proteobacteria,1RS88@1236|Gammaproteobacteria,1YKWH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
k59_559792_1	1348114.OM33_05720	3.36e-30	123.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,2Q0GY@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG2206 HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
k59_90440_1	1589733.A0A0C5AMX4_9CAUD	1.46e-42	154.0	4QAKZ@10239|Viruses,4QPYH@28883|Caudovirales,4QIYN@10662|Myoviridae	10662|Myoviridae	S	exonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_90440_2	268746.Q58MK8_BPPRM	3.38e-14	68.6	4QBEN@10239|Viruses,4QW43@35237|dsDNA viruses  no RNA stage,4QPWZ@28883|Caudovirales,4QI7M@10662|Myoviridae	10662|Myoviridae	S	Protein of unknown function (DUF3110)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1186982_1	1229780.BN381_330070	5.34e-20	94.4	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,3UW6W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k59_755599_1	311402.Avi_2884	8.94e-43	155.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,4B8DN@82115|Rhizobiaceae	28211|Alphaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_1186990_1	713586.KB900536_gene2942	1.91e-62	200.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,1WWMY@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_324667_1	1267005.KB911255_gene2897	4.62e-75	243.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria,3N7Z7@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Extracellular solute-binding protein	yejA	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
k59_285612_1	234267.Acid_7147	8.42e-107	314.0	COG0714@1|root,COG0714@2|Bacteria,3Y6Z3@57723|Acidobacteria	57723|Acidobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
k59_403942_1	34506.g5664	7.39e-55	193.0	COG0016@1|root,COG0072@1|root,KOG2472@2759|Eukaryota,KOG2784@2759|Eukaryota,3A7RT@33154|Opisthokonta,3BXEE@33208|Metazoa,3DEU8@33213|Bilateria	33208|Metazoa	J	tRNA synthetase B5 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_285613_1	244582.JQAK01000022_gene651	0.000286	41.2	2EKPQ@1|root,33EDG@2|Bacteria,1NMRQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_364420_1	1049564.TevJSym_aq00690	7.66e-16	75.9	COG4659@1|root,COG4659@2|Bacteria,1REZV@1224|Proteobacteria,1T054@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
k59_364420_2	1049564.TevJSym_aq00680	1.67e-35	126.0	COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1JBVX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfE2	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_677419_1	1089551.KE386572_gene4513	2.73e-14	76.6	COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,2TRM3@28211|Alphaproteobacteria,4BQQ4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_364428_1	1224318.DT73_15980	5.73e-18	81.6	COG3752@1|root,COG3752@2|Bacteria,1MYN3@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
k59_128952_1	1191523.MROS_1112	4.25e-46	160.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	hao	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114	1.7.2.6	ko:K10535	ko00910,ko01120,map00910,map01120	M00528,M00804	R10164	RC00383	ko00000,ko00001,ko00002,ko01000	-	-	-	Multi-haem_cyto
k59_324696_1	69293.ENSGACP00000001988	7.3e-62	220.0	COG5022@1|root,KOG0161@2759|Eukaryota,38CVC@33154|Opisthokonta,3BBPR@33208|Metazoa,3CSM1@33213|Bilateria,480QG@7711|Chordata,490K5@7742|Vertebrata,49WAH@7898|Actinopterygii	33208|Metazoa	Z	Myosin, heavy chain	MYH1	GO:0000146,GO:0000166,GO:0003008,GO:0003009,GO:0003012,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003774,GO:0003779,GO:0003824,GO:0004721,GO:0004722,GO:0005198,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005911,GO:0006139,GO:0006163,GO:0006464,GO:0006470,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006936,GO:0006941,GO:0008092,GO:0008144,GO:0008150,GO:0008152,GO:0008307,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009605,GO:0009612,GO:0009628,GO:0009629,GO:0009987,GO:0014704,GO:0014823,GO:0014850,GO:0015629,GO:0016311,GO:0016459,GO:0016460,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0016887,GO:0017018,GO:0017022,GO:0017076,GO:0017111,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0030016,GO:0030017,GO:0030029,GO:0030048,GO:0030049,GO:0030054,GO:0030554,GO:0031672,GO:0032027,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032982,GO:0032991,GO:0033275,GO:0034641,GO:0035639,GO:0035770,GO:0035994,GO:0036094,GO:0036211,GO:0036464,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044291,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0046034,GO:0046483,GO:0048856,GO:0050879,GO:0050881,GO:0050896,GO:0051015,GO:0055086,GO:0061061,GO:0070252,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:0099080,GO:0099081,GO:0099512,GO:0140096,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1990904	-	ko:K10352,ko:K17751	ko04260,ko04261,ko04530,ko05416,map04260,map04261,map04530,map05416	-	-	-	ko00000,ko00001,ko04147,ko04812	-	-	-	Myosin_N,Myosin_head,Myosin_tail_1
k59_834109_2	583345.Mmol_0108	1.47e-42	168.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2VPMU@28216|Betaproteobacteria,2KKDY@206350|Nitrosomonadales	206350|Nitrosomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_11333_1	519989.ECTPHS_01404	2.49e-57	197.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1WWSJ@135613|Chromatiales	135613|Chromatiales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_677466_1	1517681.HW45_12875	3.98e-45	163.0	COG2930@1|root,COG2930@2|Bacteria,1R34S@1224|Proteobacteria,1T63C@1236|Gammaproteobacteria,1Y3DC@135623|Vibrionales	135623|Vibrionales	S	(twin-arginine translocation) pathway signal	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_129030_1	1333507.AUTQ01000247_gene2187	4.55e-23	99.4	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,2PZM0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_90549_2	525146.Ddes_0114	9.88e-11	62.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2M9DZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1147592_1	9606.ENSP00000253099	2.37e-104	307.0	COG0088@1|root,KOG1624@2759|Eukaryota,38BG5@33154|Opisthokonta,3BF2T@33208|Metazoa,3CUTH@33213|Bilateria,4865Z@7711|Chordata,492EY@7742|Vertebrata,3JFAD@40674|Mammalia,358ZK@314146|Euarchontoglires,4M61M@9443|Primates,4N4AS@9604|Hominidae	33208|Metazoa	J	Ribosomal protein L4/L1 family	MRPL4	GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005761,GO:0005762,GO:0005829,GO:0005840,GO:0006412,GO:0006414,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019866,GO:0022411,GO:0022626,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032543,GO:0032984,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070013,GO:0070125,GO:0070126,GO:0071704,GO:0071840,GO:0097159,GO:0098798,GO:0140053,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_1108620_1	1121015.N789_04820	3.94e-05	46.2	COG0406@1|root,COG0406@2|Bacteria,1N92W@1224|Proteobacteria,1SCJF@1236|Gammaproteobacteria,1X7ZV@135614|Xanthomonadales	135614|Xanthomonadales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
k59_1108620_2	1304275.C41B8_10253	7.4e-37	128.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Secondary thiamine-phosphate synthase enzyme	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
k59_992422_1	1121396.KB893012_gene4012	7.82e-69	231.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2MHN2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_992423_1	195522.BD01_0213	7.24e-08	53.1	COG1042@1|root,arCOG01338@2157|Archaea,2XXCA@28890|Euryarchaeota,2435P@183968|Thermococci	183968|Thermococci	C	ATP-grasp domain	-	-	6.2.1.13	ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5
k59_992423_2	765177.Desmu_0896	1.36e-31	122.0	COG1042@1|root,arCOG01340@2157|Archaea,2XPR9@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	CoA_binding_2,Succ_CoA_lig
k59_912160_1	1196029.ALIM01000006_gene4862	7.34e-84	263.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,4HE3C@91061|Bacilli,1ZDEE@1386|Bacillus	91061|Bacilli	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K01612,ko:K03182	ko00130,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map01100,map01110,map01120,map01220	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k59_1108639_1	525897.Dbac_1841	1.25e-68	220.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NVJ@68525|delta/epsilon subdivisions,2WJN1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
k59_324805_1	700598.Niako_1259	9.74e-78	258.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,4NF4F@976|Bacteroidetes,1IPIS@117747|Sphingobacteriia	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_31517_2	909663.KI867150_gene472	2.43e-41	142.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MQC2@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_776370_1	765912.Thimo_3077	3.2e-43	155.0	COG2327@1|root,COG2327@2|Bacteria,1MXWP@1224|Proteobacteria,1T8HH@1236|Gammaproteobacteria,1X1U8@135613|Chromatiales	135613|Chromatiales	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
k59_112830_1	1408473.JHXO01000005_gene1744	1.12e-34	131.0	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,2FP7E@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
k59_776389_1	981336.F944_03024	3.73e-34	133.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria,3NIV4@468|Moraxellaceae	1236|Gammaproteobacteria	FP	Belongs to the GppA Ppx family	gppA	GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c42590,iECED1_1282.ECED1_4463,iECIAI39_1322.ECIAI39_2643	HD,Ppx-GppA
k59_187715_1	96561.Dole_0160	3.75e-25	99.4	COG0589@1|root,COG0589@2|Bacteria,1MZ7T@1224|Proteobacteria,42U3S@68525|delta/epsilon subdivisions,2WQ9F@28221|Deltaproteobacteria,2MKFQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_1016414_1	335543.Sfum_1225	1.02e-128	402.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_580736_1	330214.NIDE1417	3.18e-37	134.0	COG1354@1|root,COG1354@2|Bacteria,3J13J@40117|Nitrospirae	40117|Nitrospirae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
k59_854363_1	713587.THITH_06755	3.66e-113	338.0	COG0247@1|root,COG1145@1|root,COG0247@2|Bacteria,COG1145@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1WXRT@135613|Chromatiales	135613|Chromatiales	C	PFAM Cysteine-rich	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_31573_1	472759.Nhal_2009	5.6e-51	174.0	COG4783@1|root,COG4783@2|Bacteria,1RAJB@1224|Proteobacteria,1SA1F@1236|Gammaproteobacteria,1X0C0@135613|Chromatiales	135613|Chromatiales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_545015_1	349124.Hhal_2226	1.96e-33	128.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1WXVV@135613|Chromatiales	135613|Chromatiales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_973318_2	761193.Runsl_3489	2.84e-11	61.6	2DRDY@1|root,33BC0@2|Bacteria,4NVYV@976|Bacteroidetes,47S0Q@768503|Cytophagia	976|Bacteroidetes	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
k59_33905_1	933262.AXAM01000004_gene2398	5.63e-60	204.0	COG0457@1|root,COG0683@1|root,COG0457@2|Bacteria,COG0683@2|Bacteria,1R8IG@1224|Proteobacteria,42N7H@68525|delta/epsilon subdivisions,2WIUQ@28221|Deltaproteobacteria,2MHTC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC,Peripla_BP_6,TPR_16,TPR_6
k59_700428_1	765910.MARPU_10720	1.76e-33	122.0	COG4659@1|root,COG4659@2|Bacteria,1R6FE@1224|Proteobacteria,1RYZ7@1236|Gammaproteobacteria,1WXWE@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k59_700428_2	765911.Thivi_3184	2.18e-21	89.4	COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1WW5Q@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_934431_1	765910.MARPU_06900	5.34e-123	362.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,1RQ6N@1236|Gammaproteobacteria,1WWGY@135613|Chromatiales	135613|Chromatiales	C	PFAM ATPase, F1 V1 A1 complex, alpha beta subunit, nucleotide-binding domain	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_739381_1	1449355.JQNR01000005_gene3108	2.16e-41	156.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,2GIRW@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type antimicrobial peptide transport system, permease component	yknZ	-	-	ko:K02004,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	FtsX,MacB_PCD
k59_1171092_1	1150469.RSPPHO_01809	0.000101	42.7	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,2JTTP@204441|Rhodospirillales	204441|Rhodospirillales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
k59_1171092_2	331869.BAL199_06204	3.68e-55	176.0	COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,2U9A2@28211|Alphaproteobacteria,4BQXI@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
k59_1054113_1	552811.Dehly_1596	1.55e-45	159.0	COG0031@1|root,COG0031@2|Bacteria,2G698@200795|Chloroflexi,34DQK@301297|Dehalococcoidia	2|Bacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_309109_1	1238182.C882_0229	2.1e-06	51.2	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U6EY@28211|Alphaproteobacteria,2JRWX@204441|Rhodospirillales	204441|Rhodospirillales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_309109_2	105559.Nwat_3012	8.84e-38	141.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWNH@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_975739_1	1121405.dsmv_1656	1.17e-42	144.0	COG2010@1|root,COG2010@2|Bacteria,1QSQ1@1224|Proteobacteria,437J9@68525|delta/epsilon subdivisions,2X2T9@28221|Deltaproteobacteria,2MNXV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_190082_2	1121013.P873_05830	2.47e-25	100.0	COG3339@1|root,COG3339@2|Bacteria,1RAN7@1224|Proteobacteria,1S291@1236|Gammaproteobacteria,1X60S@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
k59_975754_1	1121405.dsmv_2186	4.28e-103	316.0	COG1219@1|root,COG1219@2|Bacteria,1MWIZ@1224|Proteobacteria,42N1Z@68525|delta/epsilon subdivisions,2WJUS@28221|Deltaproteobacteria,2MHMD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
k59_348436_1	550540.Fbal_0108	4.92e-80	258.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
k59_309164_1	96561.Dole_0406	2.08e-38	139.0	2BV42@1|root,32QH6@2|Bacteria,1MZ0Q@1224|Proteobacteria,42T0A@68525|delta/epsilon subdivisions,2WP4M@28221|Deltaproteobacteria,2MN8V@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_151199_2	1211114.ALIP01000014_gene1091	2.43e-30	116.0	COG3453@1|root,COG3453@2|Bacteria,1N0WC@1224|Proteobacteria,1S8TP@1236|Gammaproteobacteria,1X7C3@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
k59_348461_1	1336233.JAEH01000005_gene1858	4.44e-71	223.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,2QAJ8@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008712,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901576,GO:1903509	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iPC815.YPO0058,iYL1228.KPN_03963	Epimerase
k59_778829_1	331869.BAL199_21749	2.67e-92	275.0	COG3806@1|root,COG3806@2|Bacteria,1R52I@1224|Proteobacteria,2U2FN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG3806 Anti-sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
k59_816577_1	1242864.D187_004215	2.28e-05	52.8	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1RAHZ@1224|Proteobacteria,42UGY@68525|delta/epsilon subdivisions,2WQPI@28221|Deltaproteobacteria,2YUG9@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
k59_934534_1	933262.AXAM01000009_gene1489	1.37e-116	352.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,42PSJ@68525|delta/epsilon subdivisions,2WJDD@28221|Deltaproteobacteria,2MHWQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	reductase, alpha subunit	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
k59_504788_1	1121396.KB893012_gene4024	3.7e-77	242.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42PH3@68525|delta/epsilon subdivisions,2WJZH@28221|Deltaproteobacteria,2MIN0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_190173_1	1449126.JQKL01000014_gene2998	5.21e-39	149.0	COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia,26A4B@186813|unclassified Clostridiales	186801|Clostridia	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_934536_1	1202962.KB907154_gene809	4.97e-31	122.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alkaline phosphatase	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_504809_1	1380380.JIAX01000008_gene1899	1.06e-38	136.0	COG1376@1|root,COG1376@2|Bacteria,1MUAB@1224|Proteobacteria,2TTXM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_348498_1	1379281.AVAG01000021_gene1115	1.58e-23	103.0	COG1906@1|root,COG1906@2|Bacteria,1RAQQ@1224|Proteobacteria,42QZ0@68525|delta/epsilon subdivisions,2WMXK@28221|Deltaproteobacteria,2M7VJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF401)	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
k59_547590_1	102125.Xen7305DRAFT_00025460	3.83e-63	204.0	COG0667@1|root,COG0667@2|Bacteria,1G1XV@1117|Cyanobacteria,3VIG5@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_309244_1	1828.JOKB01000020_gene687	3.22e-28	113.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4FWN2@85025|Nocardiaceae	201174|Actinobacteria	E	GMC oxidoreductase	choD	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N
k59_1131718_2	482537.XP_008576447.1	4.04e-160	452.0	KOG0643@1|root,KOG0643@2759|Eukaryota,38D40@33154|Opisthokonta,3B9W9@33208|Metazoa,3CYW6@33213|Bilateria,480QQ@7711|Chordata,48XXP@7742|Vertebrata,3J3XC@40674|Mammalia,35BPM@314146|Euarchontoglires	33208|Metazoa	J	translation initiation factor activity	EIF3I	GO:0001525,GO:0001568,GO:0001889,GO:0001944,GO:0002040,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005852,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0007275,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009653,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0032501,GO:0032502,GO:0032991,GO:0034641,GO:0034645,GO:0035239,GO:0035295,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0048513,GO:0048514,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0061008,GO:0071541,GO:0071704,GO:0072358,GO:0072359,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K03246	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	WD40
k59_270577_1	383372.Rcas_0748	1.38e-61	201.0	COG1171@1|root,COG1171@2|Bacteria,2G6ME@200795|Chloroflexi,3776A@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_504852_1	1286106.MPL1_06517	9.16e-05	46.6	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,4616P@72273|Thiotrichales	72273|Thiotrichales	Q	toluene tolerance	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
k59_504852_2	1286106.MPL1_06512	4.86e-47	157.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,460SM@72273|Thiotrichales	72273|Thiotrichales	Q	MlaD protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
k59_1091590_1	61853.ENSNLEP00000014335	3.36e-72	219.0	29KSX@1|root,2RU25@2759|Eukaryota,3AK5T@33154|Opisthokonta,3C0JB@33208|Metazoa,3D7KI@33213|Bilateria,48E8I@7711|Chordata,49B5R@7742|Vertebrata,3JGM8@40674|Mammalia,35Q7C@314146|Euarchontoglires,4MJG5@9443|Primates	33208|Metazoa	S	Morf4 family associated protein 1	MRFAP1	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MRFAP1
k59_34128_2	1121405.dsmv_0263	4.5e-12	66.6	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2MNJX@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_270596_1	420662.Mpe_A0868	5.09e-52	188.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KJ2M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	AcrB/AcrD/AcrF family	bepE_1	-	-	ko:K03296,ko:K18138,ko:K18902	ko01501,ko01503,map01501,map01503	M00647,M00698,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_857050_1	927677.ALVU02000001_gene4017	1.51e-24	99.8	COG4589@1|root,COG4589@2|Bacteria,1GCQF@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the CDS family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
k59_857050_2	497964.CfE428DRAFT_0666	1.3e-21	92.4	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51,6.2.1.3	ko:K00655,ko:K01897	ko00061,ko00071,ko00561,ko00564,ko01100,ko01110,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00561,map00564,map01100,map01110,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086,M00089	R01280,R02241,R09381	RC00004,RC00014,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
k59_465307_1	511062.GU3_07155	9.18e-75	232.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,1Y4MG@135624|Aeromonadales	135624|Aeromonadales	S	Extradiol ring-cleavage dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
k59_233116_1	566466.NOR53_2419	3.63e-78	251.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,1J8KD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_1091615_1	1123277.KB893208_gene2814	3.68e-43	156.0	COG1167@1|root,COG1167@2|Bacteria,4NGKQ@976|Bacteroidetes,47NBW@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	yjiR	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
k59_816690_1	96561.Dole_2782	4.92e-77	242.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2MHTR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_700704_1	1121374.KB891575_gene1256	4.36e-77	245.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
k59_976000_2	1122236.KB905143_gene98	2.26e-09	59.7	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2WFQQ@28216|Betaproteobacteria,2KKTJ@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Belongs to the peptidase M48B family	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_34183_1	670307.HYPDE_31173	5.77e-101	306.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2TRIJ@28211|Alphaproteobacteria,3N7JP@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	algC	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_72855_1	589865.DaAHT2_2074	3.21e-65	222.0	COG0617@1|root,COG0618@1|root,COG2524@1|root,COG0617@2|Bacteria,COG0618@2|Bacteria,COG2524@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2WJBN@28221|Deltaproteobacteria,2MI4C@213118|Desulfobacterales	28221|Deltaproteobacteria	J	CBS domain	ccaA	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
k59_1252584_1	1121948.AUAC01000006_gene518	5.53e-37	146.0	COG1361@1|root,COG2885@1|root,COG1361@2|Bacteria,COG2885@2|Bacteria,1R5G4@1224|Proteobacteria,2UC86@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_348622_1	1163617.SCD_n02706	1.66e-69	225.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_504957_1	767434.Fraau_0370	4.39e-64	205.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,1X3Y2@135614|Xanthomonadales	135614|Xanthomonadales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
k59_504957_2	1121374.KB891588_gene3410	4.23e-40	148.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097	Mur_ligase_C,Mur_ligase_M
k59_233204_1	234267.Acid_2016	2.56e-54	187.0	COG3344@1|root,COG3344@2|Bacteria,3Y46K@57723|Acidobacteria	57723|Acidobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1,RVT_N
k59_976057_1	1121875.KB907547_gene2908	1.72e-63	221.0	COG0834@1|root,COG2172@1|root,COG2208@1|root,COG3829@1|root,COG0834@2|Bacteria,COG2172@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria,4PPGD@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_816768_1	1313172.YM304_36000	9.17e-89	270.0	COG3752@1|root,COG3752@2|Bacteria,2GNX1@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
k59_934748_1	933262.AXAM01000011_gene1760	1.06e-43	150.0	29NR7@1|root,309P5@2|Bacteria,1RDX5@1224|Proteobacteria,42S9V@68525|delta/epsilon subdivisions,2WP15@28221|Deltaproteobacteria,2MJTF@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1042120_2	930166.CD58_06900	5.97e-40	137.0	COG2030@1|root,COG2030@2|Bacteria,1MWPK@1224|Proteobacteria,1S5Y3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Dehydratase	phaJ	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k59_1004394_1	543728.Vapar_2987	5.07e-22	99.4	COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,2VHKW@28216|Betaproteobacteria,4ACF9@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1156514_1	666685.R2APBS1_3274	1.19e-66	221.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1X3X2@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_608777_1	697282.Mettu_1391	1.07e-49	169.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1XECP@135618|Methylococcales	135618|Methylococcales	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_608777_2	1515746.HR45_08210	6.79e-06	47.0	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,2QAIS@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
k59_295326_1	1122603.ATVI01000008_gene2221	7.27e-55	180.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,1RRE1@1236|Gammaproteobacteria,1X4W9@135614|Xanthomonadales	135614|Xanthomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_1077573_2	91464.S7335_82	6.53e-44	159.0	COG3447@1|root,COG4251@1|root,COG3447@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1H0GV@1129|Synechococcus	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	aphA	-	2.7.13.3	ko:K11354	ko02020,map02020	M00510	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_2,PAS_3,PAS_4,PHY,Response_reg
k59_58937_2	1123518.ARWI01000001_gene1352	1.34e-37	139.0	COG0475@1|root,COG0475@2|Bacteria,1R9PF@1224|Proteobacteria,1RRM1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_333792_2	414684.RC1_3663	3.11e-07	52.4	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria,2JPBX@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0530 Ca2 Na antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_920764_1	177437.HRM2_07800	3.15e-83	259.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria,2MKDA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_530937_1	543728.Vapar_4498	5.98e-99	306.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2VIE4@28216|Betaproteobacteria,4AJH7@80864|Comamonadaceae	28216|Betaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_1156597_1	86049.XP_008729594.1	3.03e-22	98.6	COG1786@1|root,2RQJN@2759|Eukaryota,3AG0Q@33154|Opisthokonta,3PAZ2@4751|Fungi,3QQSI@4890|Ascomycota,20KAW@147545|Eurotiomycetes	4751|Fungi	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF126,DUF521
k59_1196168_1	391735.Veis_4532	3.87e-26	107.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2VJ5H@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_177634_1	748247.AZKH_0332	0.000103	44.3	2CJJV@1|root,30VBX@2|Bacteria,1RGSF@1224|Proteobacteria,2VS5D@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_177634_2	864051.BurJ1DRAFT_4171	2.96e-37	132.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria,2VTRB@28216|Betaproteobacteria,1KNNN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
k59_569018_1	909663.KI867150_gene1970	1.24e-29	108.0	COG5443@1|root,COG5443@2|Bacteria,1RD3V@1224|Proteobacteria,42UAH@68525|delta/epsilon subdivisions,2WQUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellar FlbT family protein	flbT	-	-	ko:K06601	-	-	-	-	ko00000,ko02035	-	-	-	FlbT
k59_569018_2	933262.AXAM01000005_gene2537	7.55e-11	61.2	COG1344@1|root,COG1344@2|Bacteria,1MXC4@1224|Proteobacteria,42RME@68525|delta/epsilon subdivisions,2WN9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM flagellin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flagellin_C,Flagellin_N
k59_1196213_1	335543.Sfum_1977	2.32e-128	395.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_99894_1	236097.ADG881_849	1.76e-15	72.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,1S8W5@1236|Gammaproteobacteria,1XKVX@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
k59_99894_2	991905.SL003B_3779	3.36e-38	137.0	COG1230@1|root,COG2608@1|root,COG1230@2|Bacteria,COG2608@2|Bacteria,1MUSS@1224|Proteobacteria,2TQWX@28211|Alphaproteobacteria,4BQ80@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,HMA
k59_59044_1	60711.ENSCSAP00000014661	1.39e-122	358.0	COG0604@1|root,KOG1197@2759|Eukaryota,39MVJ@33154|Opisthokonta,3BBU1@33208|Metazoa,3CYIP@33213|Bilateria,488JV@7711|Chordata,491EC@7742|Vertebrata,3J5FK@40674|Mammalia,35EIE@314146|Euarchontoglires,4MKN9@9443|Primates,3652J@314294|Cercopithecoidea	33208|Metazoa	C	Vesicle amine transport	VAT1	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0009987,GO:0010635,GO:0010637,GO:0010639,GO:0010821,GO:0010823,GO:0012505,GO:0016020,GO:0016021,GO:0016192,GO:0019867,GO:0022603,GO:0030141,GO:0031090,GO:0031224,GO:0031410,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031982,GO:0031983,GO:0032940,GO:0033043,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046903,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051093,GO:0051128,GO:0051129,GO:0051179,GO:0051234,GO:0060205,GO:0065007,GO:0070013,GO:0097708,GO:0098588,GO:0098805,GO:0099503	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
k59_1238906_1	1163617.SCD_n02571	1.88e-57	197.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_686846_1	1217718.ALOU01000076_gene3922	4.13e-24	106.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,1K38N@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_961180_1	1232437.KL662016_gene1039	5.56e-123	366.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2MIPI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM carboxyl transferase	-	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_99917_1	1220582.RRU01S_25_01490	1.78e-86	269.0	COG0627@1|root,COG0627@2|Bacteria,1R4M6@1224|Proteobacteria,2U4X7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
k59_490870_1	439235.Dalk_2560	4.91e-66	206.0	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WKM6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
k59_490870_2	439235.Dalk_2559	2.09e-09	57.4	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MJ8N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.12.1.3,1.6.5.2,1.6.5.3	ko:K00124,ko:K00335,ko:K00355,ko:K18331	ko00130,ko00190,ko00630,ko00680,ko01100,ko01110,ko01120,ko01200,ko05200,ko05225,ko05418,map00130,map00190,map00630,map00680,map01100,map01110,map01120,map01200,map05200,map05225,map05418	M00144	R00519,R02964,R03643,R03816,R11945	RC00061,RC00819,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k59_647047_1	1340810.V5UT26_9CAUD	6.69e-36	140.0	4QHQV@10239|Viruses,4QX6C@35237|dsDNA viruses  no RNA stage,4QRJ7@28883|Caudovirales,4QIJU@10662|Myoviridae	10662|Myoviridae	S	virus tail assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_920896_1	7165.AGAP002906-PA	4.1e-21	97.4	COG0661@1|root,KOG1234@2759|Eukaryota,38G6I@33154|Opisthokonta,3BANJ@33208|Metazoa,3CUW1@33213|Bilateria,41VAA@6656|Arthropoda,3SH7Q@50557|Insecta,4502K@7147|Diptera,45GDD@7148|Nematocera	33208|Metazoa	S	ABC1 family	ADCK3	GO:0000166,GO:0001655,GO:0001822,GO:0002064,GO:0003674,GO:0003824,GO:0004672,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006091,GO:0006119,GO:0006122,GO:0006139,GO:0006163,GO:0006464,GO:0006468,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009653,GO:0009888,GO:0009987,GO:0015980,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0021549,GO:0021575,GO:0021587,GO:0021680,GO:0021692,GO:0021695,GO:0021696,GO:0022037,GO:0022900,GO:0022904,GO:0030154,GO:0030198,GO:0030554,GO:0030855,GO:0030902,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032835,GO:0032836,GO:0034641,GO:0035850,GO:0036094,GO:0036211,GO:0042180,GO:0042181,GO:0042773,GO:0042775,GO:0043062,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0048468,GO:0048513,GO:0048731,GO:0048856,GO:0048869,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0060322,GO:0060429,GO:0061005,GO:0061318,GO:0071704,GO:0071840,GO:0072001,GO:0072006,GO:0072009,GO:0072010,GO:0072015,GO:0072073,GO:0072112,GO:0072310,GO:0072311,GO:0072521,GO:0097159,GO:0097367,GO:0140096,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901661,GO:1901663	-	ko:K08869	-	-	-	-	ko00000,ko01001	-	-	-	ABC1
k59_256113_2	1260251.SPISAL_00290	5.12e-07	52.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1WVWG@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k59_1117826_1	1198232.CYCME_0063	2.51e-07	51.6	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,45ZWV@72273|Thiotrichales	72273|Thiotrichales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_569098_1	96561.Dole_2857	2.38e-40	135.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,43BIE@68525|delta/epsilon subdivisions,2X6WS@28221|Deltaproteobacteria,2MKKT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_1117843_1	1121405.dsmv_2651	1.21e-70	229.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_20263_1	61853.ENSNLEP00000001824	3.8e-110	325.0	KOG4737@1|root,KOG4737@2759|Eukaryota,39Q0Y@33154|Opisthokonta,3BDRP@33208|Metazoa,3D02K@33213|Bilateria,4865C@7711|Chordata,494G8@7742|Vertebrata,3J6J1@40674|Mammalia,35AVG@314146|Euarchontoglires,4MDK4@9443|Primates	33208|Metazoa	C	ATPase, H transporting, lysosomal accessory protein 2	ATP6AP2	GO:0001654,GO:0001664,GO:0001736,GO:0001737,GO:0001738,GO:0001775,GO:0001817,GO:0001819,GO:0001932,GO:0001990,GO:0001991,GO:0002002,GO:0002003,GO:0002009,GO:0002119,GO:0002164,GO:0002165,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003002,GO:0003008,GO:0003013,GO:0003044,GO:0003073,GO:0003081,GO:0003674,GO:0005102,GO:0005109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006887,GO:0006928,GO:0006955,GO:0007017,GO:0007018,GO:0007154,GO:0007164,GO:0007267,GO:0007268,GO:0007275,GO:0007389,GO:0007399,GO:0007423,GO:0007444,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0007610,GO:0007611,GO:0007613,GO:0007614,GO:0007616,GO:0008015,GO:0008088,GO:0008104,GO:0008150,GO:0008152,GO:0008217,GO:0008544,GO:0009314,GO:0009416,GO:0009453,GO:0009605,GO:0009628,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009888,GO:0009897,GO:0009913,GO:0009952,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010171,GO:0010467,GO:0010646,GO:0010647,GO:0010817,GO:0010970,GO:0012505,GO:0012506,GO:0015672,GO:0015988,GO:0015991,GO:0016020,GO:0016043,GO:0016192,GO:0016197,GO:0016469,GO:0016471,GO:0016485,GO:0016486,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0021532,GO:0021903,GO:0021915,GO:0022008,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030111,GO:0030141,GO:0030154,GO:0030177,GO:0030182,GO:0030659,GO:0030667,GO:0030705,GO:0030855,GO:0031090,GO:0031323,GO:0031399,GO:0031410,GO:0031982,GO:0032268,GO:0032501,GO:0032502,GO:0032908,GO:0032914,GO:0032940,GO:0032991,GO:0033036,GO:0033176,GO:0034220,GO:0034613,GO:0034641,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0035315,GO:0035316,GO:0035317,GO:0036230,GO:0040011,GO:0042119,GO:0042325,GO:0042330,GO:0042331,GO:0042445,GO:0042995,GO:0043005,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043299,GO:0043312,GO:0043408,GO:0043473,GO:0043603,GO:0044237,GO:0044238,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045055,GO:0045177,GO:0045321,GO:0046903,GO:0046907,GO:0048066,GO:0048069,GO:0048104,GO:0048513,GO:0048518,GO:0048522,GO:0048563,GO:0048569,GO:0048583,GO:0048584,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048749,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050808,GO:0050877,GO:0050886,GO:0050890,GO:0050896,GO:0051171,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051604,GO:0051641,GO:0051649,GO:0055085,GO:0060255,GO:0060322,GO:0060323,GO:0060429,GO:0060562,GO:0065007,GO:0065008,GO:0070727,GO:0070820,GO:0070821,GO:0071634,GO:0071636,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090251,GO:0090662,GO:0097458,GO:0097708,GO:0098552,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098805,GO:0098916,GO:0098930,GO:0099111,GO:0099131,GO:0099132,GO:0099503,GO:0099531,GO:0099536,GO:0099537,GO:0101002,GO:0101003,GO:0120025,GO:0120036,GO:1901564,GO:1902531,GO:1902600	-	ko:K19514	ko04614,map04614	-	-	-	ko00000,ko00001	-	-	-	Renin_r
k59_843348_1	870187.Thini_1374	7.06e-53	188.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,46034@72273|Thiotrichales	72273|Thiotrichales	U	TIGRFAM type IV pilus secretin (or competence protein) PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_569119_1	1150469.RSPPHO_02176	3.56e-79	249.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TTWE@28211|Alphaproteobacteria,2JRBD@204441|Rhodospirillales	204441|Rhodospirillales	E	Glutamine synthetase, catalytic domain	-	-	6.3.4.12	ko:K01949	-	-	-	-	ko00000,ko01000	-	-	-	Gln-synt_C
k59_256165_1	96561.Dole_0851	7.12e-97	313.0	COG0366@1|root,COG3408@1|root,COG0366@2|Bacteria,COG3408@2|Bacteria,1MWBZ@1224|Proteobacteria,43AE9@68525|delta/epsilon subdivisions,2X5U3@28221|Deltaproteobacteria,2MJ5S@213118|Desulfobacterales	28221|Deltaproteobacteria	G	alpha amylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,GDE_C,GDE_N
k59_647107_1	1411685.U062_00826	3.03e-47	160.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1J5U2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	ybbA	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_295587_1	452637.Oter_0795	3.23e-09	57.4	2E5WH@1|root,32RS6@2|Bacteria	2|Bacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_137783_2	1122612.AUBA01000004_gene558	3.44e-34	128.0	COG0446@1|root,COG0446@2|Bacteria,1QSG6@1224|Proteobacteria,2TUP1@28211|Alphaproteobacteria,2K2NT@204457|Sphingomonadales	204457|Sphingomonadales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_843384_1	319003.Bra1253DRAFT_00068	3.05e-57	193.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,3JTRC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_882667_1	1049564.TevJSym_aw00130	1.83e-56	189.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,1RYPW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S dicluster domain	dsrK	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k59_882667_2	572477.Alvin_1257	1.29e-23	96.3	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,1RYZ2@1236|Gammaproteobacteria,1WW9H@135613|Chromatiales	135613|Chromatiales	C	PFAM Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
k59_1156788_1	1125863.JAFN01000001_gene2711	3.72e-83	256.0	COG0559@1|root,COG0559@2|Bacteria,1MVZ5@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	MA20_23490	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_803344_1	1121396.KB893077_gene738	1.08e-81	263.0	COG0438@1|root,COG0438@2|Bacteria,1R3Q9@1224|Proteobacteria,42MQ2@68525|delta/epsilon subdivisions,2WM1F@28221|Deltaproteobacteria,2MQ1W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
k59_843396_1	396588.Tgr7_2630	4.01e-22	94.7	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1WVYN@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k59_726197_1	1044.EH31_05310	1.54e-71	232.0	COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,2TTX5@28211|Alphaproteobacteria,2K0AH@204457|Sphingomonadales	204457|Sphingomonadales	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
k59_217960_1	267608.RSp1675	1.73e-107	322.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,1K2WH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32
k59_1239085_1	261292.Nit79A3_2824	1.73e-90	286.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,371Q6@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_295610_1	244581.IM40_03950	3.91e-08	60.8	COG1835@1|root,COG1835@2|Bacteria,1MYXY@1224|Proteobacteria,2TUT4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
k59_569172_1	1132836.RCCGE510_22074	6.64e-89	274.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,2U1EH@28211|Alphaproteobacteria,4BMJ6@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
k59_531249_1	485915.Dret_1524	1.74e-26	110.0	COG2208@1|root,COG3829@1|root,COG2208@2|Bacteria,COG3829@2|Bacteria,1QW3X@1224|Proteobacteria,43CY1@68525|delta/epsilon subdivisions,2X866@28221|Deltaproteobacteria,2MHC2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	PAS,SpoIIE
k59_334035_1	156889.Mmc1_2398	1.78e-38	150.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Pyruvate phosphate dikinase	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_59183_1	555793.WSK_0649	2.1e-07	53.9	COG0438@1|root,COG0438@2|Bacteria,1R3Q9@1224|Proteobacteria,2TUPF@28211|Alphaproteobacteria,2K0U6@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_1004790_2	1443665.JACA01000024_gene3381	5.85e-42	145.0	COG4430@1|root,COG4430@2|Bacteria,4NWI7@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
k59_491018_1	1317118.ATO8_16345	8.83e-112	332.0	COG0329@1|root,COG0329@2|Bacteria,1MXM5@1224|Proteobacteria,2TUAG@28211|Alphaproteobacteria,4KNZW@93682|Roseivivax	28211|Alphaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_921017_1	42099.EPrPV00000023594	5.98e-54	172.0	COG0590@1|root,KOG1018@2759|Eukaryota	2759|Eukaryota	FJ	deaminase activity	FCY1	GO:0003674,GO:0003824,GO:0004131,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006206,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009451,GO:0009987,GO:0016070,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019858,GO:0034641,GO:0034654,GO:0043094,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046087,GO:0046131,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
k59_803372_1	573370.DMR_33120	5.31e-100	317.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,42PJV@68525|delta/epsilon subdivisions,2WKRG@28221|Deltaproteobacteria,2M98V@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
k59_451577_1	626887.J057_17970	1.64e-72	231.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,464MZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_963637_2	335543.Sfum_3630	7.03e-53	174.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria,2MRZT@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
k59_102366_1	439235.Dalk_3239	6.26e-50	170.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2MIIH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	heat shock protein DnaJ domain protein	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_419497_1	555779.Dthio_PD3072	7.75e-94	279.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,42R7A@68525|delta/epsilon subdivisions,2WN7K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_1007676_1	493475.GARC_3504	1.14e-31	121.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,465EU@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_336430_1	9541.XP_005593848.1	0.0	879.0	KOG3529@1|root,KOG3529@2759|Eukaryota,38CYB@33154|Opisthokonta,3BB9D@33208|Metazoa,3CSFA@33213|Bilateria,486XW@7711|Chordata,48V0I@7742|Vertebrata,3JFNV@40674|Mammalia,35G8N@314146|Euarchontoglires,4M7GV@9443|Primates,365JD@314294|Cercopithecoidea	33208|Metazoa	S	Ezrin/radixin/moesin family	MSN	GO:0000003,GO:0000226,GO:0000578,GO:0000785,GO:0000902,GO:0000904,GO:0001654,GO:0001738,GO:0001745,GO:0001751,GO:0001754,GO:0001771,GO:0001775,GO:0001885,GO:0001931,GO:0002009,GO:0002064,GO:0002119,GO:0002164,GO:0002165,GO:0002168,GO:0002376,GO:0002682,GO:0002685,GO:0003002,GO:0003006,GO:0003158,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003779,GO:0005102,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005543,GO:0005546,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005700,GO:0005703,GO:0005737,GO:0005819,GO:0005829,GO:0005856,GO:0005886,GO:0005902,GO:0005911,GO:0005912,GO:0005938,GO:0006403,GO:0006405,GO:0006810,GO:0006913,GO:0006928,GO:0006935,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007028,GO:0007088,GO:0007154,GO:0007155,GO:0007159,GO:0007163,GO:0007165,GO:0007166,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007314,GO:0007315,GO:0007318,GO:0007346,GO:0007350,GO:0007351,GO:0007368,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007423,GO:0007424,GO:0007444,GO:0007552,GO:0007560,GO:0007610,GO:0007617,GO:0007618,GO:0007619,GO:0008017,GO:0008037,GO:0008049,GO:0008092,GO:0008104,GO:0008150,GO:0008283,GO:0008284,GO:0008289,GO:0008358,GO:0008360,GO:0008361,GO:0008595,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009791,GO:0009798,GO:0009799,GO:0009855,GO:0009880,GO:0009886,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009898,GO:0009948,GO:0009952,GO:0009986,GO:0009987,GO:0009988,GO:0009994,GO:0010033,GO:0010468,GO:0010564,GO:0010604,GO:0010628,GO:0010638,GO:0012505,GO:0012506,GO:0014070,GO:0015630,GO:0015631,GO:0015931,GO:0016020,GO:0016043,GO:0016057,GO:0016323,GO:0016324,GO:0016335,GO:0016336,GO:0016477,GO:0016545,GO:0019098,GO:0019221,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0021700,GO:0022008,GO:0022406,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022610,GO:0022612,GO:0022614,GO:0023052,GO:0030010,GO:0030029,GO:0030030,GO:0030036,GO:0030054,GO:0030100,GO:0030141,GO:0030154,GO:0030175,GO:0030182,GO:0030315,GO:0030334,GO:0030659,GO:0030667,GO:0030674,GO:0030855,GO:0030859,GO:0030865,GO:0030866,GO:0031090,GO:0031122,GO:0031143,GO:0031175,GO:0031253,GO:0031254,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031334,GO:0031410,GO:0031527,GO:0031974,GO:0031982,GO:0032153,GO:0032154,GO:0032155,GO:0032268,GO:0032270,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032870,GO:0032879,GO:0032880,GO:0032886,GO:0032887,GO:0032888,GO:0032943,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0033574,GO:0033993,GO:0034097,GO:0034453,GO:0034613,GO:0035003,GO:0035088,GO:0035089,GO:0035091,GO:0035148,GO:0035149,GO:0035152,GO:0035239,GO:0035282,GO:0035295,GO:0035327,GO:0035722,GO:0040011,GO:0040012,GO:0042051,GO:0042052,GO:0042098,GO:0042110,GO:0042127,GO:0042176,GO:0042221,GO:0042330,GO:0042383,GO:0042391,GO:0042461,GO:0042462,GO:0042995,GO:0043167,GO:0043168,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043254,GO:0043296,GO:0043622,GO:0044085,GO:0044087,GO:0044089,GO:0044091,GO:0044422,GO:0044424,GO:0044425,GO:0044427,GO:0044430,GO:0044433,GO:0044444,GO:0044446,GO:0044448,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0045177,GO:0045179,GO:0045197,GO:0045198,GO:0045313,GO:0045321,GO:0045433,GO:0045446,GO:0045732,GO:0045787,GO:0045807,GO:0045840,GO:0045931,GO:0046530,GO:0046649,GO:0046651,GO:0046907,GO:0048065,GO:0048468,GO:0048469,GO:0048471,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048563,GO:0048569,GO:0048592,GO:0048599,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048749,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050657,GO:0050658,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050896,GO:0050900,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051168,GO:0051169,GO:0051171,GO:0051173,GO:0051179,GO:0051233,GO:0051234,GO:0051236,GO:0051246,GO:0051247,GO:0051270,GO:0051286,GO:0051493,GO:0051495,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0060090,GO:0060179,GO:0060236,GO:0060255,GO:0060341,GO:0060429,GO:0060541,GO:0060562,GO:0060627,GO:0061028,GO:0061162,GO:0061245,GO:0061339,GO:0061564,GO:0062033,GO:0065007,GO:0065008,GO:0070161,GO:0070486,GO:0070489,GO:0070507,GO:0070661,GO:0070671,GO:0070727,GO:0070887,GO:0071310,GO:0071345,GO:0071349,GO:0071394,GO:0071396,GO:0071407,GO:0071437,GO:0071495,GO:0071593,GO:0071702,GO:0071705,GO:0071801,GO:0071803,GO:0071840,GO:0071944,GO:0072499,GO:0072657,GO:0072676,GO:0072678,GO:0072686,GO:0080090,GO:0090066,GO:0090068,GO:0090162,GO:0090224,GO:0090596,GO:0097159,GO:0097435,GO:0097485,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098590,GO:0098609,GO:0098687,GO:0098796,GO:0098797,GO:0098805,GO:0098858,GO:0099503,GO:0099568,GO:0099738,GO:0110028,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:1901363,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1901981,GO:1902115,GO:1902117,GO:1902846,GO:1902936,GO:1902965,GO:1902966,GO:1903361,GO:1903362,GO:1903364,GO:1903649,GO:1903651,GO:1903827,GO:1903829,GO:1905666,GO:1905668,GO:1990023,GO:1990778,GO:2000145,GO:2000401,GO:2000641,GO:2000643,GO:2001252	-	ko:K05762,ko:K05763,ko:K08007	ko04530,ko04670,ko04810,ko04971,ko05130,ko05162,ko05205,ko05206,map04530,map04670,map04810,map04971,map05130,map05162,map05205,map05206	-	-	-	ko00000,ko00001,ko04147,ko04812	-	-	-	ERM,FERM_C,FERM_M,FERM_N
k59_221010_1	879212.DespoDRAFT_01850	1.42e-16	77.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria,2MK76@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
k59_419517_1	1227453.C444_06481	5.68e-15	76.3	COG2233@1|root,arCOG02805@2157|Archaea,2XTK8@28890|Euryarchaeota,23SUG@183963|Halobacteria	183963|Halobacteria	F	COG2233 Xanthine uracil permeases	-	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
k59_1007687_1	933262.AXAM01000033_gene1642	6.07e-104	319.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MI52@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_885059_1	1453501.JELR01000001_gene2832	1.45e-93	290.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,465WS@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt_2	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_156497_1	1249627.D779_0923	7.23e-05	50.4	COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1S7FF@1236|Gammaproteobacteria,1WYCM@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
k59_156512_1	1158338.JNLJ01000005_gene1621	2.77e-34	135.0	COG0542@1|root,COG0542@2|Bacteria,2G3N7@200783|Aquificae	200783|Aquificae	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
k59_195384_2	396588.Tgr7_2713	1.46e-26	106.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1WX43@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
k59_78167_1	395965.Msil_0200	3.29e-26	107.0	COG1877@1|root,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,2U9NF@28211|Alphaproteobacteria,3NB3P@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	Trehalose-phosphatase	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
k59_156708_1	411154.GFO_0059	2.31e-46	155.0	COG3547@1|root,COG3547@2|Bacteria,4NF2F@976|Bacteroidetes,1HXCM@117743|Flavobacteriia	976|Bacteroidetes	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_78180_1	43179.ENSSTOP00000001493	2.88e-72	228.0	KOG1523@1|root,KOG1523@2759|Eukaryota,38FWT@33154|Opisthokonta,3BD4C@33208|Metazoa,3CSS9@33213|Bilateria,4874V@7711|Chordata,48Y4I@7742|Vertebrata,3JAYS@40674|Mammalia,35NJE@314146|Euarchontoglires,4PW34@9989|Rodentia	33208|Metazoa	Z	Arp2/3 complex-mediated actin nucleation	ARPC1B	GO:0000902,GO:0000904,GO:0001654,GO:0001700,GO:0001745,GO:0002252,GO:0002253,GO:0002376,GO:0002429,GO:0002431,GO:0002433,GO:0002682,GO:0002684,GO:0002757,GO:0002764,GO:0002768,GO:0003674,GO:0003779,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005885,GO:0006810,GO:0006886,GO:0006897,GO:0006909,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007154,GO:0007155,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007399,GO:0007409,GO:0007413,GO:0007423,GO:0008037,GO:0008038,GO:0008064,GO:0008092,GO:0008104,GO:0008150,GO:0008407,GO:0008593,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010638,GO:0010646,GO:0010647,GO:0014070,GO:0015031,GO:0015629,GO:0015833,GO:0016043,GO:0016192,GO:0022008,GO:0022402,GO:0022416,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0030029,GO:0030030,GO:0030036,GO:0030037,GO:0030154,GO:0030182,GO:0030588,GO:0030589,GO:0030832,GO:0030833,GO:0030838,GO:0031175,GO:0031334,GO:0031344,GO:0031346,GO:0031532,GO:0032271,GO:0032273,GO:0032355,GO:0032501,GO:0032502,GO:0032535,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033627,GO:0033993,GO:0034314,GO:0034613,GO:0036284,GO:0038093,GO:0038094,GO:0038096,GO:0042221,GO:0042886,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043627,GO:0044087,GO:0044089,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045010,GO:0045184,GO:0045747,GO:0046907,GO:0048013,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048592,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048749,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051015,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051489,GO:0051491,GO:0051493,GO:0051495,GO:0051641,GO:0051649,GO:0051716,GO:0060491,GO:0061564,GO:0065007,GO:0065008,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0090066,GO:0090527,GO:0090596,GO:0097435,GO:0098657,GO:0106030,GO:0110053,GO:0120032,GO:0120034,GO:0120035,GO:0120036,GO:0120039,GO:1901700,GO:1902903,GO:1902905	-	ko:K05757	ko04144,ko04666,ko04810,ko05100,ko05130,ko05131,ko05132,map04144,map04666,map04810,map05100,map05130,map05131,map05132	-	-	-	ko00000,ko00001,ko04131,ko04812	-	-	-	WD40
k59_822179_1	998674.ATTE01000001_gene2055	5.82e-68	228.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,4609P@72273|Thiotrichales	72273|Thiotrichales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
k59_195533_1	765912.Thimo_0084	1.9e-47	160.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1WY4Z@135613|Chromatiales	135613|Chromatiales	NU	PFAM Fimbrial assembly	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
k59_822309_2	1298593.TOL_1806	1.05e-22	94.7	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,1XM73@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TerB
k59_195572_1	985762.SAGN_01315	2.32e-14	77.4	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,4GXEZ@90964|Staphylococcaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
k59_195595_1	1265313.HRUBRA_00318	3.2e-51	177.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
k59_195634_2	754027.HMPREF9554_02483	1.9e-06	53.1	COG0630@1|root,COG1067@1|root,COG0630@2|Bacteria,COG1067@2|Bacteria,2J6SU@203691|Spirochaetes	203691|Spirochaetes	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_632369_1	1265505.ATUG01000002_gene1716	1.94e-45	155.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42Y9W@68525|delta/epsilon subdivisions,2WUQG@28221|Deltaproteobacteria,2MMZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_123130_1	118797.XP_007457841.1	2.66e-290	793.0	COG0513@1|root,KOG0327@2759|Eukaryota,38CTS@33154|Opisthokonta,3BC8P@33208|Metazoa,3CVNR@33213|Bilateria,481CR@7711|Chordata,48ZRJ@7742|Vertebrata,3JF61@40674|Mammalia,4IY0D@91561|Cetartiodactyla	33208|Metazoa	A	initiation factor	EIF4A1	GO:0000003,GO:0000122,GO:0000339,GO:0000381,GO:0002164,GO:0002165,GO:0002168,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003743,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006355,GO:0006357,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0007275,GO:0007276,GO:0007277,GO:0007279,GO:0007281,GO:0007292,GO:0007349,GO:0007444,GO:0007446,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0008356,GO:0009058,GO:0009059,GO:0009653,GO:0009791,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017145,GO:0019219,GO:0019222,GO:0019538,GO:0019827,GO:0019953,GO:0022412,GO:0022414,GO:0030154,GO:0030718,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0034641,GO:0034645,GO:0035265,GO:0035295,GO:0035770,GO:0036464,GO:0040007,GO:0042078,GO:0042623,GO:0043043,GO:0043170,GO:0043186,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045495,GO:0045892,GO:0045934,GO:0046483,GO:0048024,GO:0048132,GO:0048468,GO:0048477,GO:0048513,GO:0048519,GO:0048523,GO:0048589,GO:0048609,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0050684,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051301,GO:0051704,GO:0060255,GO:0060293,GO:0060429,GO:0065007,GO:0070013,GO:0070035,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0098722,GO:0098727,GO:0098728,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903311,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K03257	ko03013,map03013	M00428	-	-	ko00000,ko00001,ko00002,ko03012,ko03019,ko04147	-	-	-	DEAD,Helicase_C
k59_436128_1	1121013.P873_01305	1.57e-104	333.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1X3T3@135614|Xanthomonadales	135614|Xanthomonadales	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_240430_1	1461693.ATO10_10875	1.64e-52	174.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2TQS4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	cbbR1	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_240430_2	754476.Q7A_522	1.12e-14	72.4	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,4604Y@72273|Thiotrichales	72273|Thiotrichales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_515027_1	1234664.AMRO01000025_gene2057	4.71e-22	97.1	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,4HDHI@91061|Bacilli,1WEU4@129337|Geobacillus	91061|Bacilli	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k59_710297_1	1316936.K678_07101	7.42e-54	190.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2TRS4@28211|Alphaproteobacteria,2JQTC@204441|Rhodospirillales	204441|Rhodospirillales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
k59_1141501_1	1121948.AUAC01000003_gene2530	6.7e-06	44.7	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,43YF2@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_710298_1	574966.KB898649_gene124	7.97e-66	216.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1XI5M@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the peptidase S11 family	dacA	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
k59_397518_1	187272.Mlg_2766	1.88e-44	149.0	COG0494@1|root,COG0494@2|Bacteria,1MYSK@1224|Proteobacteria,1SB8U@1236|Gammaproteobacteria,1WZ0K@135613|Chromatiales	135613|Chromatiales	L	Belongs to the Nudix hydrolase family	-	-	3.6.1.17	ko:K01518	ko00230,ko00240,map00230,map00240	-	R00184,R00969,R01232,R02805	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
k59_985282_1	648757.Rvan_3366	1.89e-69	219.0	COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2TUXV@28211|Alphaproteobacteria,3N74N@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_945662_1	118797.XP_007456266.1	4.96e-62	196.0	COG0588@1|root,KOG0235@2759|Eukaryota,38GF6@33154|Opisthokonta,3BA4I@33208|Metazoa,3CVWK@33213|Bilateria,485KR@7711|Chordata,49041@7742|Vertebrata,3J3S8@40674|Mammalia,4J696@91561|Cetartiodactyla	33208|Metazoa	G	phosphoglycerate mutase	PGAM1	GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006110,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009889,GO:0009894,GO:0009987,GO:0010675,GO:0012505,GO:0016051,GO:0016052,GO:0016053,GO:0016192,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0019899,GO:0019900,GO:0019901,GO:0030141,GO:0030808,GO:0030811,GO:0031323,GO:0031326,GO:0031329,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032787,GO:0032940,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034774,GO:0036230,GO:0042119,GO:0042325,GO:0042866,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043455,GO:0043456,GO:0043467,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045730,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046903,GO:0046939,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051174,GO:0051179,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051234,GO:0055086,GO:0055114,GO:0060205,GO:0060255,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0062012,GO:0065007,GO:0070013,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:0097708,GO:0099503,GO:0101002,GO:1900371,GO:1900542,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:1903578,GO:1904813,GO:2001169	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
k59_240469_1	861299.J421_1491	1.24e-69	229.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1ZSZ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CE	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
k59_84360_1	335543.Sfum_3470	5.51e-91	282.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MR03@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_358332_2	1232437.KL662020_gene705	1.48e-48	169.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_553884_1	439235.Dalk_1049	2.5e-13	65.9	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,42V1I@68525|delta/epsilon subdivisions,2WRH0@28221|Deltaproteobacteria,2MKP1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
k59_475567_1	247634.GPB2148_1491	7.66e-48	166.0	COG1028@1|root,COG1028@2|Bacteria,1REA0@1224|Proteobacteria,1SMHH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_279602_1	1121396.KB892901_gene2206	7.13e-16	72.0	COG1146@1|root,COG1146@2|Bacteria,1RC9N@1224|Proteobacteria,42QXF@68525|delta/epsilon subdivisions,2WMRJ@28221|Deltaproteobacteria,2MJFT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	reductase, beta subunit	aprB	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4,Fer4_9
k59_84367_1	187272.Mlg_2779	7.41e-62	216.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1WW36@135613|Chromatiales	135613|Chromatiales	E	PFAM NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
k59_828153_1	1057002.KB905372_gene6077	1.12e-99	302.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TTHU@28211|Alphaproteobacteria,4BM93@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
k59_279622_1	316067.Geob_3086	1.97e-50	172.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2WJU8@28221|Deltaproteobacteria,43TJH@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_749758_1	1408445.JHXP01000007_gene376	1.03e-06	46.6	2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_397577_1	887062.HGR_05449	8.45e-71	226.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,4AAI7@80864|Comamonadaceae	28216|Betaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase
k59_515091_1	82654.Pse7367_1525	2.37e-37	129.0	arCOG08935@1|root,32Z08@2|Bacteria,1GAUH@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_710392_1	525897.Dbac_1842	6.81e-126	365.0	COG1840@1|root,COG1840@2|Bacteria,1N9WT@1224|Proteobacteria	1224|Proteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
k59_515096_1	1121940.AUDZ01000015_gene1487	1.34e-27	112.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1XJHK@135619|Oceanospirillales	135619|Oceanospirillales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_5624_1	1535422.ND16A_0537	8.45e-41	147.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RQGU@1236|Gammaproteobacteria,2Q7FM@267889|Colwelliaceae	1236|Gammaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	acdP	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
k59_671503_1	9940.ENSOARP00000006269	7.8e-111	334.0	COG0459@1|root,KOG0364@2759|Eukaryota,38GPW@33154|Opisthokonta,3BFX2@33208|Metazoa,3CYB8@33213|Bilateria,47ZAK@7711|Chordata,48XID@7742|Vertebrata,3JCEM@40674|Mammalia,4IW6M@91561|Cetartiodactyla	33208|Metazoa	O	Chaperonin containing TCP1 subunit 3	CCT3	GO:0000003,GO:0002199,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005832,GO:0005856,GO:0005874,GO:0005886,GO:0006457,GO:0006458,GO:0006810,GO:0007338,GO:0007339,GO:0008037,GO:0008150,GO:0009566,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009988,GO:0010556,GO:0010557,GO:0010604,GO:0010638,GO:0015630,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019953,GO:0022414,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031647,GO:0032204,GO:0032206,GO:0032210,GO:0032212,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033044,GO:0035036,GO:0042623,GO:0043209,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044183,GO:0044297,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044703,GO:0045935,GO:0046931,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050821,GO:0051052,GO:0051054,GO:0051082,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051704,GO:0060255,GO:0060341,GO:0061077,GO:0065003,GO:0065007,GO:0065008,GO:0070201,GO:0070202,GO:0070203,GO:0071840,GO:0071944,GO:0080090,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0101031,GO:1901998,GO:1903827,GO:1903829,GO:1904356,GO:1904358,GO:1904814,GO:1904816,GO:1904851,GO:1904951,GO:2000112,GO:2000278,GO:2000573,GO:2001252	-	ko:K09495	-	-	-	-	ko00000,ko03036,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_397599_1	13735.ENSPSIP00000001938	4.71e-119	345.0	29K1R@1|root,2RTAM@2759|Eukaryota,39YR1@33154|Opisthokonta,3BPA4@33208|Metazoa,3D0TK@33213|Bilateria,48CB2@7711|Chordata,496S2@7742|Vertebrata	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1063437_1	489825.LYNGBM3L_35050	8.91e-14	68.2	COG0521@1|root,COG0521@2|Bacteria,1G514@1117|Cyanobacteria,1HB1C@1150|Oscillatoriales	1117|Cyanobacteria	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638,ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_1063437_2	472759.Nhal_2468	3.02e-92	284.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1WVYA@135613|Chromatiales	135613|Chromatiales	H	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_44527_2	1517681.HW45_25615	1.73e-42	160.0	COG3659@1|root,COG3659@2|Bacteria,1R8TI@1224|Proteobacteria,1S21B@1236|Gammaproteobacteria,1XVR4@135623|Vibrionales	135623|Vibrionales	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
k59_201194_1	8469.XP_007054025.1	1.16e-55	192.0	KOG0211@1|root,KOG0211@2759|Eukaryota,38DRM@33154|Opisthokonta,3B9UG@33208|Metazoa,3CXII@33213|Bilateria,47ZD8@7711|Chordata,491BQ@7742|Vertebrata,4CD90@8459|Testudines	33208|Metazoa	T	meiotic spindle elongation	PPP2R1A	GO:0000003,GO:0000070,GO:0000086,GO:0000159,GO:0000184,GO:0000188,GO:0000212,GO:0000226,GO:0000278,GO:0000280,GO:0000775,GO:0000819,GO:0000956,GO:0001558,GO:0001932,GO:0001933,GO:0003674,GO:0003823,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0005739,GO:0005813,GO:0005814,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006139,GO:0006275,GO:0006355,GO:0006396,GO:0006401,GO:0006402,GO:0006464,GO:0006469,GO:0006470,GO:0006629,GO:0006643,GO:0006665,GO:0006672,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006914,GO:0006915,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007059,GO:0007062,GO:0007098,GO:0007099,GO:0007135,GO:0007143,GO:0007154,GO:0007165,GO:0007275,GO:0007276,GO:0007292,GO:0007346,GO:0008150,GO:0008152,GO:0008219,GO:0008287,GO:0008380,GO:0009056,GO:0009057,GO:0009790,GO:0009792,GO:0009889,GO:0009892,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010389,GO:0010467,GO:0010468,GO:0010556,GO:0010563,GO:0010564,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010921,GO:0010941,GO:0010942,GO:0012501,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017151,GO:0019208,GO:0019219,GO:0019220,GO:0019222,GO:0019439,GO:0019538,GO:0019888,GO:0019899,GO:0019932,GO:0019953,GO:0022402,GO:0022406,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030030,GO:0030031,GO:0030111,GO:0030155,GO:0030234,GO:0030308,GO:0031023,GO:0031323,GO:0031324,GO:0031326,GO:0031399,GO:0031400,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033673,GO:0034641,GO:0034655,GO:0035303,GO:0035304,GO:0035330,GO:0035331,GO:0035556,GO:0035770,GO:0036211,GO:0036464,GO:0040008,GO:0042221,GO:0042325,GO:0042326,GO:0042509,GO:0042532,GO:0042578,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043186,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043405,GO:0043407,GO:0043408,GO:0043409,GO:0043412,GO:0043549,GO:0043603,GO:0043666,GO:0043900,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0045132,GO:0045144,GO:0045495,GO:0045595,GO:0045859,GO:0045926,GO:0045936,GO:0046425,GO:0046426,GO:0046483,GO:0046626,GO:0046627,GO:0046700,GO:0046982,GO:0046983,GO:0048285,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048609,GO:0048856,GO:0050730,GO:0050732,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051128,GO:0051171,GO:0051172,GO:0051174,GO:0051177,GO:0051179,GO:0051225,GO:0051231,GO:0051232,GO:0051239,GO:0051246,GO:0051248,GO:0051252,GO:0051276,GO:0051298,GO:0051304,GO:0051306,GO:0051321,GO:0051336,GO:0051338,GO:0051348,GO:0051445,GO:0051640,GO:0051641,GO:0051704,GO:0051716,GO:0051726,GO:0051754,GO:0060255,GO:0060271,GO:0060281,GO:0060284,GO:0060293,GO:0061919,GO:0061983,GO:0065003,GO:0065007,GO:0065009,GO:0070192,GO:0070262,GO:0070601,GO:0070925,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0072686,GO:0080090,GO:0090304,GO:0097711,GO:0098534,GO:0098687,GO:0098772,GO:0098813,GO:0120031,GO:0120036,GO:0140013,GO:0140014,GO:0140056,GO:0140096,GO:1900076,GO:1900077,GO:1900193,GO:1901360,GO:1901361,GO:1901564,GO:1901575,GO:1901987,GO:1901990,GO:1902494,GO:1902531,GO:1902532,GO:1902749,GO:1903046,GO:1903047,GO:1903293,GO:1903429,GO:1903506,GO:1903538,GO:1904892,GO:1904893,GO:1905879,GO:1990405,GO:1990904,GO:2000112,GO:2000241,GO:2001141,GO:2001233,GO:2001235,GO:2001236,GO:2001238,GO:2001239,GO:2001241	-	ko:K03456	ko03015,ko04071,ko04111,ko04113,ko04114,ko04151,ko04152,ko04261,ko04350,ko04390,ko04391,ko04530,ko04728,ko04730,ko05142,ko05160,ko05165,map03015,map04071,map04111,map04113,map04114,map04151,map04152,map04261,map04350,map04390,map04391,map04530,map04728,map04730,map05142,map05160,map05165	-	-	-	ko00000,ko00001,ko01009,ko03036	-	-	-	HEAT,HEAT_2
k59_1102652_1	395495.Lcho_4131	7.16e-60	189.0	COG3245@1|root,COG3245@2|Bacteria,1RG2V@1224|Proteobacteria,2VS0Q@28216|Betaproteobacteria,1KNH3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
k59_358402_1	482537.XP_008571006.1	1.12e-76	247.0	COG0443@1|root,KOG0102@2759|Eukaryota,38EJA@33154|Opisthokonta,3BABY@33208|Metazoa,3CT5K@33213|Bilateria,48BEX@7711|Chordata,48XVF@7742|Vertebrata,3JAJ8@40674|Mammalia,35G7Y@314146|Euarchontoglires	33208|Metazoa	O	negative regulation of hematopoietic stem cell differentiation	HSPA9	GO:0000422,GO:0001101,GO:0002262,GO:0002376,GO:0002520,GO:0002682,GO:0002683,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006457,GO:0006464,GO:0006468,GO:0006611,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006914,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007584,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009295,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010918,GO:0010941,GO:0014070,GO:0015031,GO:0015833,GO:0016043,GO:0016226,GO:0016310,GO:0017134,GO:0019221,GO:0019538,GO:0019838,GO:0019899,GO:0022411,GO:0022607,GO:0023052,GO:0030097,GO:0030099,GO:0030154,GO:0030218,GO:0031072,GO:0031163,GO:0031625,GO:0031667,GO:0031974,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0033036,GO:0033273,GO:0034097,GO:0034101,GO:0034613,GO:0035722,GO:0036211,GO:0042221,GO:0042391,GO:0042493,GO:0042592,GO:0042645,GO:0042886,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043200,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045595,GO:0045596,GO:0045637,GO:0045638,GO:0045646,GO:0045647,GO:0045838,GO:0046777,GO:0046907,GO:0048513,GO:0048519,GO:0048523,GO:0048534,GO:0048731,GO:0048856,GO:0048869,GO:0048872,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051082,GO:0051087,GO:0051093,GO:0051168,GO:0051169,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051241,GO:0051593,GO:0051641,GO:0051649,GO:0051716,GO:0051881,GO:0060548,GO:0061726,GO:0061919,GO:0065007,GO:0065008,GO:0070013,GO:0070555,GO:0070584,GO:0070671,GO:0070727,GO:0070887,GO:0071310,GO:0071345,GO:0071347,GO:0071349,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0097066,GO:0097068,GO:1901532,GO:1901533,GO:1901564,GO:1901698,GO:1901700,GO:1902036,GO:1902037,GO:1903008,GO:1903706,GO:1903707,GO:1904386,GO:2000026,GO:2000736,GO:2000737	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_240543_1	1116472.MGMO_41c00150	8.85e-61	191.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XF8T@135618|Methylococcales	135618|Methylococcales	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_240543_2	1163408.UU9_15210	1.63e-06	48.5	COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1X39A@135614|Xanthomonadales	135614|Xanthomonadales	E	Glycine cleavage system regulatory protein	gcvR	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
k59_123278_1	1336235.JAEG01000002_gene217	2.51e-50	177.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,4B9XK@82115|Rhizobiaceae	28211|Alphaproteobacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH5_C,Proton_antipo_M,Proton_antipo_N
k59_123278_2	990285.RGCCGE502_07861	2.47e-06	46.6	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2U93P@28211|Alphaproteobacteria,4BF8F@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
k59_1141643_2	1121396.KB892990_gene4479	9.64e-64	203.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,42R15@68525|delta/epsilon subdivisions,2WJR6@28221|Deltaproteobacteria,2MIHT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_1181301_1	323848.Nmul_A2478	9.11e-17	80.9	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,372DD@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k59_123294_1	388413.ALPR1_10385	1.97e-84	257.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,47JU8@768503|Cytophagia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_84464_1	933262.AXAM01000025_gene3413	8.65e-129	374.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2WIPW@28221|Deltaproteobacteria,2MI53@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Radical SAM domain protein	yhcC-1	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
k59_279729_1	335543.Sfum_0821	3.92e-181	542.0	COG1148@1|root,COG2204@1|root,COG1148@2|Bacteria,COG2204@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_oxidored,Fer4,Fer4_7,NAD_binding_8,Pyr_redox_2,Response_reg
k59_5723_1	314260.PB2503_04937	5.68e-90	288.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,2TTR0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	peptidase S9A, prolyl oligopeptidase domain protein beta-propeller	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_5723_2	660470.Theba_0903	3.4e-08	56.6	COG0530@1|root,COG0530@2|Bacteria,2GCTS@200918|Thermotogae	200918|Thermotogae	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_475690_1	1123401.JHYQ01000015_gene1348	1.09e-25	104.0	COG1073@1|root,COG1225@1|root,COG1073@2|Bacteria,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,462CZ@72273|Thiotrichales	72273|Thiotrichales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_475690_2	1123367.C666_08075	2.06e-30	108.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,2VVVU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
k59_1141702_1	318167.Sfri_2288	1.65e-96	296.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,1T20X@1236|Gammaproteobacteria,2QAVG@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
k59_671633_1	744979.R2A130_1950	1.21e-60	202.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,2TSCV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Major facilitator superfamily	MA20_25070	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k59_279765_1	1382356.JQMP01000004_gene528	5.79e-72	233.0	COG0477@1|root,COG0477@2|Bacteria,2G89T@200795|Chloroflexi,27Y75@189775|Thermomicrobia	189775|Thermomicrobia	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_279779_1	744985.HIMB59_00005380	5.63e-94	281.0	COG0395@1|root,COG0395@2|Bacteria,1MXEM@1224|Proteobacteria,2TUQV@28211|Alphaproteobacteria,4BS0Y@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM Binding-protein-dependent transport system inner membrane component	ycjP	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k59_515220_2	745411.B3C1_14223	1.37e-54	182.0	COG0515@1|root,COG0515@2|Bacteria,1QUW7@1224|Proteobacteria,1T23C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
k59_515228_1	553385.JEMF01000009_gene1909	1.96e-24	106.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1XHM0@135619|Oceanospirillales	135619|Oceanospirillales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_945851_1	631362.Thi970DRAFT_01756	2.85e-17	87.4	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,1WWK2@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1102761_1	880072.Desac_2461	4.32e-33	127.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2WIMV@28221|Deltaproteobacteria,2MRCB@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
k59_671661_1	9541.XP_005568004.1	2.97e-124	355.0	COG5171@1|root,KOG0864@2759|Eukaryota,38EUB@33154|Opisthokonta,3BACZ@33208|Metazoa,3CZPW@33213|Bilateria,480Q4@7711|Chordata,48YYV@7742|Vertebrata,3J773@40674|Mammalia,35JGT@314146|Euarchontoglires,4MCHW@9443|Primates,369TU@314294|Cercopithecoidea	33208|Metazoa	U	Ran-specific GTPase-activating protein	RANBP1	GO:0000082,GO:0000226,GO:0000278,GO:0001101,GO:0003674,GO:0005092,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006403,GO:0006405,GO:0006508,GO:0006511,GO:0006606,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007088,GO:0007154,GO:0007165,GO:0007275,GO:0007346,GO:0007399,GO:0008104,GO:0008150,GO:0008152,GO:0008536,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010564,GO:0010638,GO:0010720,GO:0010975,GO:0010976,GO:0012505,GO:0014070,GO:0015031,GO:0015630,GO:0015833,GO:0015931,GO:0016032,GO:0016043,GO:0017016,GO:0017038,GO:0019538,GO:0019899,GO:0019941,GO:0022008,GO:0022402,GO:0023052,GO:0030154,GO:0030163,GO:0030234,GO:0030424,GO:0030695,GO:0031267,GO:0031344,GO:0031346,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032838,GO:0032886,GO:0033036,GO:0033043,GO:0033267,GO:0033365,GO:0033993,GO:0034504,GO:0034613,GO:0042221,GO:0042886,GO:0042995,GO:0043005,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0045184,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045787,GO:0045840,GO:0045931,GO:0046602,GO:0046604,GO:0046605,GO:0046607,GO:0046677,GO:0046907,GO:0048518,GO:0048522,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050657,GO:0050658,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051020,GO:0051094,GO:0051128,GO:0051130,GO:0051168,GO:0051169,GO:0051170,GO:0051179,GO:0051234,GO:0051236,GO:0051239,GO:0051240,GO:0051493,GO:0051495,GO:0051603,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051785,GO:0051960,GO:0051962,GO:0060284,GO:0060589,GO:0065007,GO:0065009,GO:0070507,GO:0070542,GO:0070727,GO:0070887,GO:0071229,GO:0071236,GO:0071310,GO:0071396,GO:0071398,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072750,GO:0090068,GO:0097458,GO:0098772,GO:0099568,GO:0120025,GO:0120035,GO:0120038,GO:0120111,GO:1901344,GO:1901564,GO:1901565,GO:1901575,GO:1901700,GO:1901701,GO:1903047,GO:1904115,GO:2000026	-	ko:K15306	ko05166,ko05203,map05166,map05203	-	-	-	ko00000,ko00001	-	-	-	Ran_BP1
k59_515245_1	1121405.dsmv_0456	7.13e-08	57.0	COG1729@1|root,COG1729@2|Bacteria,1RGD4@1224|Proteobacteria,42S9U@68525|delta/epsilon subdivisions,2WP0U@28221|Deltaproteobacteria,2MK2Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,YfiO
k59_201327_1	13333.ERN19444	6.43e-16	85.1	COG1404@1|root,2QPQR@2759|Eukaryota,37HQV@33090|Viridiplantae,3GC98@35493|Streptophyta	35493|Streptophyta	O	subtilisin-like protease	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8
k59_1063577_1	1131553.JIBI01000064_gene1039	5.11e-27	101.0	COG2963@1|root,COG2963@2|Bacteria,1N06K@1224|Proteobacteria,2VUF3@28216|Betaproteobacteria,373SY@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
k59_44640_1	349124.Hhal_0419	2.04e-126	372.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,1RRUS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_632645_1	1318628.MARLIPOL_12709	7.25e-68	220.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,4644B@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	COG4962 Flp pilus assembly protein, ATPase CpaF	tadA	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
k59_869872_1	573413.Spirs_2766	7.24e-93	279.0	COG1079@1|root,COG1079@2|Bacteria,2JA5I@203691|Spirochaetes	203691|Spirochaetes	P	transport system permease	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_321478_1	351016.RAZWK3B_04530	2.26e-38	136.0	COG0411@1|root,COG0411@2|Bacteria,1PFED@1224|Proteobacteria,2V7G7@28211|Alphaproteobacteria,2P3C7@2433|Roseobacter	28211|Alphaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_321478_2	935840.JAEQ01000023_gene4364	3.12e-12	65.9	COG4177@1|root,COG4177@2|Bacteria,1Q5UA@1224|Proteobacteria,2TT00@28211|Alphaproteobacteria,43IMJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_243459_1	243265.plu1511	2.99e-14	73.6	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_243459_2	158190.SpiGrapes_0211	1.81e-11	61.6	COG0724@1|root,COG0724@2|Bacteria,2J8UF@203691|Spirochaetes	203691|Spirochaetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_1066075_1	1167006.UWK_02396	5.78e-32	129.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42PJQ@68525|delta/epsilon subdivisions,2WKR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	iAF987.Gmet_3470	CBS,Voltage_CLC
k59_165084_1	545264.KB898755_gene2830	6.24e-86	267.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1WW29@135613|Chromatiales	135613|Chromatiales	S	PFAM Uncharacterised protein family UPF0027	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k59_361280_1	641491.DND132_3161	1.23e-17	90.9	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,42PJV@68525|delta/epsilon subdivisions,2WKRG@28221|Deltaproteobacteria,2M98V@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
k59_1144411_1	768671.ThimaDRAFT_2793	7.82e-46	160.0	COG3039@1|root,COG3039@2|Bacteria,1P2FY@1224|Proteobacteria,1SRZF@1236|Gammaproteobacteria,1X1EC@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_830861_1	439235.Dalk_5088	8.63e-51	175.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
k59_478383_1	338963.Pcar_0515	3.74e-61	197.0	COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,42NVQ@68525|delta/epsilon subdivisions,2WJFT@28221|Deltaproteobacteria,43TVE@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
k59_909139_1	1121033.AUCF01000036_gene3985	2.35e-74	235.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,2JPQM@204441|Rhodospirillales	204441|Rhodospirillales	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
k59_909139_2	435908.IDSA_03870	0.000242	43.5	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,2QG7H@267893|Idiomarinaceae	1236|Gammaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ybhF	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_969643_2	1160707.AJIK01000020_gene1862	0.00045	43.5	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,26CVN@186818|Planococcaceae	91061|Bacilli	S	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like	yabN	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
k59_654544_1	395493.BegalDRAFT_2685	8.19e-55	184.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,45ZS7@72273|Thiotrichales	72273|Thiotrichales	NU	TIGRFAM general secretion pathway protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_264274_2	1202962.KB907157_gene3609	1.25e-23	98.6	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_890587_1	1217720.ALOX01000018_gene858	6.02e-92	287.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,2TTW4@28211|Alphaproteobacteria,2JQY3@204441|Rhodospirillales	204441|Rhodospirillales	T	PrkA AAA domain	-	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
k59_426779_1	1408473.JHXO01000010_gene3623	4.63e-17	82.4	COG3301@1|root,COG3301@2|Bacteria,4NITJ@976|Bacteroidetes	976|Bacteroidetes	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_890604_1	9694.XP_007090985.1	1.74e-124	387.0	COG1196@1|root,KOG0018@2759|Eukaryota,38CKC@33154|Opisthokonta,3B9FX@33208|Metazoa,3CT58@33213|Bilateria,480UI@7711|Chordata,48UWF@7742|Vertebrata,3JCWT@40674|Mammalia,3EHEW@33554|Carnivora	33208|Metazoa	D	Structural maintenance of chromosomes	SMC1A	GO:0000003,GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000775,GO:0000776,GO:0000785,GO:0000790,GO:0000793,GO:0000794,GO:0000819,GO:0000902,GO:0000904,GO:0000922,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005700,GO:0005737,GO:0005819,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006275,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0007064,GO:0007088,GO:0007275,GO:0007346,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0008156,GO:0008278,GO:0009314,GO:0009411,GO:0009416,GO:0009607,GO:0009628,GO:0009653,GO:0009719,GO:0009790,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010165,GO:0010212,GO:0010468,GO:0010556,GO:0010558,GO:0010564,GO:0010605,GO:0010629,GO:0010948,GO:0015630,GO:0016043,GO:0016319,GO:0016322,GO:0016358,GO:0016363,GO:0019219,GO:0019222,GO:0019827,GO:0021700,GO:0022008,GO:0022402,GO:0022414,GO:0030030,GO:0030154,GO:0030182,GO:0030893,GO:0031175,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032875,GO:0032876,GO:0032886,GO:0032989,GO:0032990,GO:0032991,GO:0033043,GO:0033554,GO:0034399,GO:0034641,GO:0035327,GO:0036033,GO:0042551,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044877,GO:0045786,GO:0045934,GO:0046483,GO:0046982,GO:0046983,GO:0048285,GO:0048468,GO:0048469,GO:0048513,GO:0048519,GO:0048523,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051128,GO:0051171,GO:0051172,GO:0051276,GO:0051321,GO:0051493,GO:0051716,GO:0051726,GO:0051783,GO:0060236,GO:0060255,GO:0060322,GO:0065007,GO:0070013,GO:0070507,GO:0071216,GO:0071495,GO:0071695,GO:0071704,GO:0071840,GO:0072396,GO:0072402,GO:0072423,GO:0072686,GO:0080090,GO:0090169,GO:0090224,GO:0090304,GO:0090329,GO:0097159,GO:0097431,GO:0098687,GO:0098727,GO:0098813,GO:0120036,GO:0120039,GO:0140014,GO:1901360,GO:1901363,GO:1901673,GO:1902115,GO:1903047,GO:2000104,GO:2000112,GO:2000113	-	ko:K06636,ko:K19719	ko04110,ko04111,ko04113,ko04114,ko04151,ko04510,ko04512,ko04974,ko05165,map04110,map04111,map04113,map04114,map04151,map04510,map04512,map04974,map05165	-	-	-	ko00000,ko00001,ko00536,ko03036	-	-	-	SMC_N,SMC_hinge
k59_27993_1	998086.F8SK38_9CAUD	1.86e-47	179.0	4QITB@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_109300_1	335543.Sfum_0384	3.23e-57	196.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,42QBI@68525|delta/epsilon subdivisions,2WJWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
k59_851129_1	991905.SL003B_2940	6.73e-35	138.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,4BPPH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Transglycosylase	pbp	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_1048641_1	635013.TherJR_0856	1.47e-110	337.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,2604P@186807|Peptococcaceae	186801|Clostridia	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_890629_1	43989.cce_1519	8.31e-08	59.7	COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,1G3J0@1117|Cyanobacteria,3KFW5@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
k59_694735_1	658187.LDG_7768	4.5e-66	217.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,1RP02@1236|Gammaproteobacteria,1JCV8@118969|Legionellales	118969|Legionellales	E	ammonia-lyase activity	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
k59_184481_1	1123373.ATXI01000010_gene1069	1.06e-16	73.6	COG1837@1|root,COG1837@2|Bacteria,2GI1Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_932191_2	941449.dsx2_0002	3.16e-37	133.0	COG1309@1|root,COG1309@2|Bacteria,1N6R3@1224|Proteobacteria,42N4M@68525|delta/epsilon subdivisions,2WQ5F@28221|Deltaproteobacteria,2M9UA@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
k59_1168755_1	1123057.P872_04760	9.64e-47	171.0	COG3291@1|root,COG5498@1|root,COG3291@2|Bacteria,COG5498@2|Bacteria,4PPR2@976|Bacteroidetes,47YQN@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_230516_1	767817.Desgi_1928	6.61e-59	203.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,260PA@186807|Peptococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_386393_1	935840.JAEQ01000001_gene2985	4.34e-35	133.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,43K5E@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HTH_Tnp_1,Transposase_20
k59_545034_1	1123360.thalar_02603	2.52e-07	49.3	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2UF59@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_545034_2	751994.AGIG01000002_gene916	1.92e-71	216.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,1J62I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
k59_973346_2	439235.Dalk_5099	5.78e-58	181.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2MK8A@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_230535_1	323261.Noc_3032	1.06e-89	274.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1WWNM@135613|Chromatiales	135613|Chromatiales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_814115_1	933262.AXAM01000001_gene326	3.23e-88	284.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2MI4Z@213118|Desulfobacterales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_932226_1	342610.Patl_1728	8.56e-24	95.9	COG2236@1|root,COG2236@2|Bacteria,1MXS1@1224|Proteobacteria,1RPSD@1236|Gammaproteobacteria,2Q137@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	F	Phosphoribosyl transferase domain	hpt	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
k59_932226_2	338969.Rfer_3142	2.84e-75	231.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2VRA6@28216|Betaproteobacteria,4ABBS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the LOG family	yvdD_1	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
k59_932231_1	314292.VAS14_02648	1.42e-92	295.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria,1XTH6@135623|Vibrionales	135623|Vibrionales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_894147_1	56780.SYN_01481	2.84e-69	232.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MQZ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_1051904_1	1123392.AQWL01000004_gene2790	5.12e-17	87.4	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,1KS47@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k59_1208160_1	768671.ThimaDRAFT_3923	6.12e-57	192.0	COG3039@1|root,COG3039@2|Bacteria,1P2FY@1224|Proteobacteria,1SRZF@1236|Gammaproteobacteria,1X1EC@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_386454_1	96561.Dole_2132	2.82e-54	177.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42QN5@68525|delta/epsilon subdivisions,2WMD7@28221|Deltaproteobacteria,2MJC9@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_112997_1	96561.Dole_2789	8.26e-49	172.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2MHTV@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
k59_430877_1	675815.VOA_001749	9.07e-20	94.0	COG0671@1|root,COG0671@2|Bacteria,1N3TP@1224|Proteobacteria,1SADV@1236|Gammaproteobacteria,1Y2AB@135623|Vibrionales	135623|Vibrionales	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
k59_620473_1	396588.Tgr7_2034	3.83e-131	394.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RYC8@1236|Gammaproteobacteria,1WX4W@135613|Chromatiales	135613|Chromatiales	G	Transketolase central region	-	-	-	-	-	-	-	-	-	-	-	-	XFP,XFP_N
k59_386478_1	439235.Dalk_0888	2.55e-101	310.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2MIZ1@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Starch synthase catalytic	-	-	2.4.1.21,3.2.1.1	ko:K00703,ko:K01176	ko00500,ko01100,ko01110,ko02026,ko04973,map00500,map01100,map01110,map02026,map04973	M00565	R02108,R02112,R02421,R11262	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GH13,GT5	-	Glyco_trans_1_4,Glyco_transf_5,Glycos_transf_1
k59_1129366_1	1502724.FF80_03135	4.38e-65	212.0	COG1653@1|root,COG1653@2|Bacteria,1N8AS@1224|Proteobacteria,2U19M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
k59_462951_1	639283.Snov_3078	2.08e-67	210.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2TTX4@28211|Alphaproteobacteria,3EY3Q@335928|Xanthobacteraceae	28211|Alphaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	MA20_18155	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
k59_386487_1	1123073.KB899245_gene181	2.99e-51	184.0	28HYC@1|root,2Z83T@2|Bacteria,1QEBM@1224|Proteobacteria,1RRCK@1236|Gammaproteobacteria,1X5W1@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_462953_1	247634.GPB2148_3180	5.27e-16	73.6	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,1J73I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
k59_462953_2	247634.GPB2148_2930	3.94e-64	202.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1J4IH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Cell shape-determining protein	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_580877_1	1453501.JELR01000001_gene3240	3.31e-44	159.0	28MBM@1|root,2ZAQ2@2|Bacteria,1R5V6@1224|Proteobacteria,1S0K0@1236|Gammaproteobacteria,4662R@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_580877_2	570268.ANBB01000050_gene4102	1.49e-06	52.4	COG0515@1|root,COG1674@1|root,COG0515@2|Bacteria,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4EGSR@85012|Streptosporangiales	201174|Actinobacteria	D	Ftsk_gamma	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
k59_346176_1	1230476.C207_00115	6.04e-29	115.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria,3JW31@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
k59_1208247_1	933262.AXAM01000020_gene15	6.01e-62	201.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,42MEN@68525|delta/epsilon subdivisions,2WIYF@28221|Deltaproteobacteria,2MIJH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_1129410_1	857087.Metme_2682	5.67e-75	236.0	COG0524@1|root,COG0524@2|Bacteria,1MWX4@1224|Proteobacteria,1RU49@1236|Gammaproteobacteria,1XETS@135618|Methylococcales	135618|Methylococcales	G	Belongs to the carbohydrate kinase PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
k59_113072_1	335543.Sfum_0745	3.68e-31	122.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria,2MR4C@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_973496_1	1384056.N787_11455	2.35e-37	140.0	COG1668@1|root,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,1RQT1@1236|Gammaproteobacteria,1X3GM@135614|Xanthomonadales	135614|Xanthomonadales	CP	permease	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3
k59_973496_2	500153.JOEK01000001_gene3495	1.89e-09	59.7	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_973528_1	96561.Dole_0980	1.3e-14	73.2	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,2MIAK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpA	hrpA	-	3.6.4.13	ko:K03578,ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
k59_1250434_1	1110502.TMO_2125	8e-33	131.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,2JPR8@204441|Rhodospirillales	204441|Rhodospirillales	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
k59_1168933_1	1121405.dsmv_0777	7.79e-62	206.0	COG0309@1|root,COG0546@1|root,COG0309@2|Bacteria,COG0546@2|Bacteria,1N04A@1224|Proteobacteria,437IA@68525|delta/epsilon subdivisions,2WYKF@28221|Deltaproteobacteria,2MP0D@213118|Desulfobacterales	28221|Deltaproteobacteria	O	AIR synthase related protein, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
k59_973582_1	1282361.ABAC402_18830	6.19e-08	57.4	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,2KGA0@204458|Caulobacterales	204458|Caulobacterales	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k59_31859_1	1049564.TevJSym_al00210	2.82e-128	398.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1J7JF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_1250488_1	335543.Sfum_0268	1.47e-103	312.0	COG0034@1|root,COG0034@2|Bacteria,1R7JX@1224|Proteobacteria,42MAC@68525|delta/epsilon subdivisions,2WKFD@28221|Deltaproteobacteria,2MQ6P@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Glutamine amidotransferase domain	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
k59_502715_1	38727.Pavir.J35172.1.p	0.000677	46.6	2CBEU@1|root,2QQQU@2759|Eukaryota,37SIM@33090|Viridiplantae,3GB6Q@35493|Streptophyta,3KS6P@4447|Liliopsida,3I3P2@38820|Poales	35493|Streptophyta	-	-	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009507,GO:0009509,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009575,GO:0009579,GO:0009611,GO:0009628,GO:0009642,GO:0009644,GO:0009765,GO:0009941,GO:0009987,GO:0010206,GO:0010207,GO:0015979,GO:0016020,GO:0016043,GO:0019538,GO:0019684,GO:0019898,GO:0022607,GO:0030091,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0034622,GO:0035448,GO:0042170,GO:0042651,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0055035,GO:0065003,GO:0071704,GO:0071840,GO:1901564	-	-	-	-	-	-	-	-	-	-	-
k59_581035_1	697282.Mettu_0674	8.89e-89	290.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1XDJT@135618|Methylococcales	135618|Methylococcales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_230814_1	644282.Deba_2031	6.49e-13	68.9	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,42QQ7@68525|delta/epsilon subdivisions,2WN8Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k59_973633_1	1265505.ATUG01000003_gene386	2.05e-66	225.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
k59_70680_1	570952.ATVH01000011_gene537	1.49e-39	135.0	2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,2UCBC@28211|Alphaproteobacteria,2JTPS@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_307102_1	331678.Cphamn1_1230	1.57e-44	155.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
k59_894407_1	1167006.UWK_00959	8.13e-62	198.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2WP66@28221|Deltaproteobacteria,2MK8S@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
k59_973671_2	9707.XP_004410950.1	1.23e-82	254.0	2C13H@1|root,2QTJ5@2759|Eukaryota,38CJB@33154|Opisthokonta,3BJ0S@33208|Metazoa,3CTMU@33213|Bilateria,481W8@7711|Chordata,496KB@7742|Vertebrata,3J55D@40674|Mammalia,3EQ1Y@33554|Carnivora	33208|Metazoa	T	mannose-6-phosphate receptor	M6PR	GO:0000139,GO:0000323,GO:0002790,GO:0003674,GO:0004888,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005765,GO:0005768,GO:0005770,GO:0005773,GO:0005774,GO:0005794,GO:0005802,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0006897,GO:0006898,GO:0007034,GO:0007041,GO:0007154,GO:0007165,GO:0008104,GO:0008150,GO:0008333,GO:0009306,GO:0009987,GO:0012505,GO:0012506,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0023052,GO:0030133,GO:0030135,GO:0030136,GO:0030659,GO:0030662,GO:0030665,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031982,GO:0031984,GO:0032588,GO:0032940,GO:0033036,GO:0033299,GO:0034613,GO:0038023,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045184,GO:0046903,GO:0046907,GO:0048471,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0060089,GO:0061024,GO:0065007,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0097708,GO:0098588,GO:0098657,GO:0098791,GO:0098805,GO:0098852,GO:1905394	-	ko:K10089	ko04142,ko04145,map04142,map04145	-	-	-	ko00000,ko00001,ko04091,ko04147	-	-	-	Man-6-P_recep
k59_581089_1	398580.Dshi_1053	4.13e-24	98.6	COG1176@1|root,COG1176@2|Bacteria,1R9JI@1224|Proteobacteria,2U4J9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
k59_307117_2	1121918.ARWE01000001_gene188	2.24e-56	178.0	COG4852@1|root,COG4852@2|Bacteria,1MZHP@1224|Proteobacteria,42TD7@68525|delta/epsilon subdivisions,2WPIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
k59_545342_1	1121405.dsmv_2921	5.53e-91	291.0	COG0493@1|root,COG2878@1|root,COG0493@2|Bacteria,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,42MPF@68525|delta/epsilon subdivisions,2X5BJ@28221|Deltaproteobacteria,2MISB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fer4,Fer4_20,Fer4_9,Pyr_redox_2
k59_894428_1	935840.JAEQ01000004_gene537	1.27e-73	238.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,2TT7U@28211|Alphaproteobacteria,43H78@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
k59_894428_2	501479.ACNW01000112_gene3981	6.02e-10	59.7	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
k59_814430_1	1144275.COCOR_01016	1.35e-19	92.8	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2YU0Y@29|Myxococcales	28221|Deltaproteobacteria	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
k59_32003_1	765912.Thimo_2787	2.51e-137	404.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_1250596_1	572477.Alvin_2052	5.76e-37	143.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1WXD9@135613|Chromatiales	135613|Chromatiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_857503_2	439235.Dalk_5241	2.73e-47	154.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria,42URZ@68525|delta/epsilon subdivisions,2WQ58@28221|Deltaproteobacteria,2MKGK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_465760_1	13689.BV96_01504	3.52e-74	244.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,2TQK2@28211|Alphaproteobacteria,2K2X9@204457|Sphingomonadales	204457|Sphingomonadales	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
k59_115791_1	1535422.ND16A_1280	3.71e-27	113.0	COG0265@1|root,COG0265@2|Bacteria,1RBDX@1224|Proteobacteria	1224|Proteobacteria	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
k59_583836_1	1265505.ATUG01000001_gene3591	1.6e-39	146.0	COG0247@1|root,COG0247@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria,2MIBB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Fer4_9,FlpD
k59_271043_1	1403819.BATR01000112_gene3802	6.98e-09	62.8	COG1566@1|root,COG1566@2|Bacteria,46VGK@74201|Verrucomicrobia,2IV9K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
k59_817162_1	1300345.LF41_1809	4.23e-99	293.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RSA2@1236|Gammaproteobacteria,1X3CK@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC transporter	tptC	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_817162_2	1122604.JONR01000006_gene2748	3.3e-82	258.0	COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,1RPZF@1236|Gammaproteobacteria,1X3MX@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1211105_1	51337.XP_004662863.1	5.21e-132	392.0	COG0443@1|root,KOG0100@2759|Eukaryota,38BPF@33154|Opisthokonta,3B99M@33208|Metazoa,3CZ71@33213|Bilateria,4817Y@7711|Chordata,48WW0@7742|Vertebrata,3JA4R@40674|Mammalia,35HE6@314146|Euarchontoglires,4PXMG@9989|Rodentia	33208|Metazoa	O	plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate	HSPA5	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005783,GO:0005788,GO:0005789,GO:0005790,GO:0005793,GO:0005886,GO:0006355,GO:0006357,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006810,GO:0006915,GO:0006950,GO:0006983,GO:0006984,GO:0006986,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009057,GO:0009267,GO:0009314,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009719,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010042,GO:0010212,GO:0010243,GO:0010332,GO:0010466,GO:0010468,GO:0010498,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010648,GO:0010720,GO:0010941,GO:0010951,GO:0010975,GO:0010976,GO:0012501,GO:0012505,GO:0014070,GO:0014074,GO:0016020,GO:0016021,GO:0016246,GO:0016441,GO:0016458,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017015,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0019904,GO:0019941,GO:0021549,GO:0021575,GO:0021577,GO:0021587,GO:0021589,GO:0021680,GO:0021695,GO:0022008,GO:0022037,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030162,GO:0030163,GO:0030176,GO:0030182,GO:0030334,GO:0030335,GO:0030431,GO:0030433,GO:0030496,GO:0030512,GO:0030554,GO:0030902,GO:0030968,GO:0031047,GO:0031224,GO:0031227,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031344,GO:0031346,GO:0031396,GO:0031398,GO:0031399,GO:0031401,GO:0031625,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031984,GO:0032091,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032507,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032991,GO:0033036,GO:0033365,GO:0033554,GO:0034097,GO:0034613,GO:0034620,GO:0034663,GO:0034975,GO:0034976,GO:0035194,GO:0035437,GO:0035639,GO:0035690,GO:0035966,GO:0035967,GO:0036003,GO:0036094,GO:0036335,GO:0036498,GO:0036499,GO:0036500,GO:0036503,GO:0040012,GO:0040017,GO:0040019,GO:0040029,GO:0042149,GO:0042175,GO:0042220,GO:0042221,GO:0042493,GO:0042592,GO:0042594,GO:0042981,GO:0043021,GO:0043022,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043154,GO:0043161,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043279,GO:0043281,GO:0043393,GO:0043496,GO:0043618,GO:0043620,GO:0043632,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045185,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045861,GO:0045893,GO:0045935,GO:0045944,GO:0045995,GO:0046677,GO:0046683,GO:0046872,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048532,GO:0048583,GO:0048585,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048872,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051082,GO:0051087,GO:0051094,GO:0051098,GO:0051100,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051270,GO:0051272,GO:0051336,GO:0051346,GO:0051402,GO:0051591,GO:0051592,GO:0051603,GO:0051641,GO:0051651,GO:0051716,GO:0051787,GO:0051960,GO:0051962,GO:0052547,GO:0052548,GO:0060255,GO:0060284,GO:0060322,GO:0060359,GO:0060548,GO:0060904,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070670,GO:0070727,GO:0070848,GO:0070887,GO:0070972,GO:0070997,GO:0071214,GO:0071216,GO:0071236,GO:0071241,GO:0071248,GO:0071277,GO:0071287,GO:0071310,GO:0071320,GO:0071345,GO:0071353,GO:0071363,GO:0071407,GO:0071417,GO:0071478,GO:0071479,GO:0071480,GO:0071495,GO:0071496,GO:0071704,GO:0071944,GO:0072347,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0090074,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0097159,GO:0097367,GO:0097501,GO:0098827,GO:0104004,GO:0120035,GO:1900101,GO:1900102,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998,GO:1902074,GO:1902680,GO:1903320,GO:1903322,GO:1903332,GO:1903506,GO:1903508,GO:1903573,GO:1903844,GO:1903845,GO:1903891,GO:1903894,GO:1903895,GO:1903897,GO:1904313,GO:1905897,GO:1990089,GO:1990090,GO:1990440,GO:2000026,GO:2000112,GO:2000116,GO:2000117,GO:2000145,GO:2000147,GO:2001141	-	ko:K09490	ko03060,ko04141,ko04918,ko05020,map03060,map04141,map04918,map05020	-	-	-	ko00000,ko00001,ko03110,ko04131,ko04147	1.A.33	-	-	HSP70
k59_465785_1	1123253.AUBD01000001_gene1737	3.67e-47	165.0	COG1462@1|root,COG1462@2|Bacteria,1Q8KJ@1224|Proteobacteria,1RU2Q@1236|Gammaproteobacteria,1X6HV@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidoglycan-synthase activator LpoB	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
k59_1211150_1	335543.Sfum_0306	3.52e-83	261.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2MQXU@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_976483_2	316057.RPD_1859	1.18e-37	137.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2TRM9@28211|Alphaproteobacteria,3JU1G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Nitronate monooxygenase	MA20_16415	-	-	-	-	-	-	-	-	-	-	-	NMO
k59_233663_2	221988.MS0622	6.06e-26	109.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1Y7HY@135625|Pasteurellales	135625|Pasteurellales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_38041_1	666685.R2APBS1_3594	1.4e-31	117.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,1X64J@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k59_313128_1	1268237.G114_06170	5.69e-86	276.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	fadE	GO:0003674,GO:0003824,GO:0003995,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	iSbBS512_1146.SbBS512_E0217	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
k59_469161_1	1136163.M565_ctg5P0837	9.96e-76	252.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1XUED@135623|Vibrionales	135623|Vibrionales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_1095671_1	751994.AGIG01000036_gene2182	1.56e-96	293.0	COG1593@1|root,COG1593@2|Bacteria,1MUHY@1224|Proteobacteria,1RYC3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_938837_1	1500890.JQNL01000001_gene2044	0.000159	49.3	COG2222@1|root,COG2222@2|Bacteria,1MXC7@1224|Proteobacteria,1RS53@1236|Gammaproteobacteria,1X3UH@135614|Xanthomonadales	135614|Xanthomonadales	M	Iron dicitrate transport regulator FecR	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
k59_508877_1	1415775.U729_212	4.44e-13	71.2	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,36DTX@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	sagG	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_508877_2	1415778.JQMM01000001_gene900	3.15e-23	100.0	COG0842@1|root,COG0842@2|Bacteria,1QTBE@1224|Proteobacteria,1RNG9@1236|Gammaproteobacteria,1J4E1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
k59_1214530_1	396588.Tgr7_1993	4.69e-19	87.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,1WWIJ@135613|Chromatiales	135613|Chromatiales	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
k59_1214530_2	314278.NB231_03175	5.27e-23	99.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,1RNP1@1236|Gammaproteobacteria,1WWFF@135613|Chromatiales	135613|Chromatiales	V	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_704753_1	1123368.AUIS01000005_gene294	1.52e-05	54.3	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,2NCMM@225057|Acidithiobacillales	225057|Acidithiobacillales	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_1214550_1	378806.STAUR_2940	7.13e-38	140.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWSR@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1095725_1	573413.Spirs_2768	6.17e-105	320.0	COG3845@1|root,COG3845@2|Bacteria,2J9Q1@203691|Spirochaetes	203691|Spirochaetes	S	pfam abc	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
k59_469226_2	1255043.TVNIR_0568	1.57e-126	370.0	28I2K@1|root,2ZAEK@2|Bacteria,1R9HK@1224|Proteobacteria,1SJV2@1236|Gammaproteobacteria,1X001@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_469226_4	1122132.AQYH01000006_gene3405	3.63e-12	63.5	2ERDP@1|root,345HM@2|Bacteria,1P3AJ@1224|Proteobacteria,2UVUS@28211|Alphaproteobacteria,4BGWK@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1488
k59_587543_1	1227487.C474_11745	2.3e-49	161.0	COG0251@1|root,arCOG01630@2157|Archaea,2XY4I@28890|Euryarchaeota,23X7B@183963|Halobacteria	183963|Halobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k59_664547_1	9601.ENSPPYP00000023890	2.07e-91	270.0	2DZJ3@1|root,2S72N@2759|Eukaryota,3A39B@33154|Opisthokonta,3BQE6@33208|Metazoa,3D7GA@33213|Bilateria,48EZ1@7711|Chordata,49BIQ@7742|Vertebrata,3JGSH@40674|Mammalia,35Q4Q@314146|Euarchontoglires,4MJ6H@9443|Primates,4N0KJ@9604|Hominidae	33208|Metazoa	O	Serglycin	SRGN	GO:0000323,GO:0001817,GO:0001818,GO:0002576,GO:0002791,GO:0002792,GO:0003674,GO:0005488,GO:0005518,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005794,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006915,GO:0006996,GO:0007154,GO:0007165,GO:0008104,GO:0008150,GO:0008152,GO:0008219,GO:0008626,GO:0009987,GO:0010256,GO:0010467,GO:0012501,GO:0012505,GO:0016043,GO:0016050,GO:0016192,GO:0016485,GO:0019538,GO:0023052,GO:0030141,GO:0030278,GO:0030279,GO:0030500,GO:0030502,GO:0031091,GO:0031093,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032879,GO:0032880,GO:0032940,GO:0033036,GO:0033363,GO:0033364,GO:0033365,GO:0033366,GO:0033367,GO:0033368,GO:0033370,GO:0033371,GO:0033373,GO:0033374,GO:0033375,GO:0033377,GO:0033379,GO:0033380,GO:0033382,GO:0034613,GO:0034774,GO:0042588,GO:0042629,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044238,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045055,GO:0045185,GO:0046903,GO:0048519,GO:0048523,GO:0050707,GO:0050708,GO:0050709,GO:0050710,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051093,GO:0051179,GO:0051223,GO:0051224,GO:0051234,GO:0051235,GO:0051239,GO:0051241,GO:0051604,GO:0051641,GO:0051651,GO:0051716,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0070167,GO:0070168,GO:0070201,GO:0070727,GO:0071704,GO:0071840,GO:0090087,GO:0097190,GO:0097708,GO:0099503,GO:1901564,GO:1903530,GO:1903531,GO:1904950,GO:2000026	-	ko:K06849	-	-	-	-	ko00000,ko00535,ko04516	-	-	-	Serglycin
k59_743910_2	95619.PM1_0200995	2.35e-70	216.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k59_743910_3	545276.KB898724_gene1911	1.49e-61	201.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1WW0I@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_469332_1	30611.ENSOGAP00000007223	1.75e-96	300.0	KOG1676@1|root,KOG1676@2759|Eukaryota,38H75@33154|Opisthokonta,3BHJ2@33208|Metazoa,3CTFY@33213|Bilateria,4872V@7711|Chordata,492GI@7742|Vertebrata,3JEY4@40674|Mammalia,35GXA@314146|Euarchontoglires,4M7Q9@9443|Primates	33208|Metazoa	A	KH-type splicing regulatory protein	KHSRP	GO:0000003,GO:0000375,GO:0000381,GO:0001505,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006397,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0007276,GO:0007283,GO:0008150,GO:0008152,GO:0008380,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010494,GO:0010556,GO:0010558,GO:0010586,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0010984,GO:0010985,GO:0010988,GO:0010989,GO:0016070,GO:0016071,GO:0017091,GO:0017148,GO:0019219,GO:0019222,GO:0019439,GO:0019953,GO:0022414,GO:0030425,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031329,GO:0031331,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032501,GO:0032504,GO:0032991,GO:0033119,GO:0034097,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0034660,GO:0035770,GO:0035925,GO:0036464,GO:0036477,GO:0042221,GO:0042995,GO:0043005,GO:0043025,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043484,GO:0043487,GO:0043488,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044703,GO:0045019,GO:0045428,GO:0045934,GO:0045935,GO:0046483,GO:0046700,GO:0048024,GO:0048025,GO:0048232,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048609,GO:0050684,GO:0050686,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0051716,GO:0060255,GO:0061013,GO:0061014,GO:0061157,GO:0061158,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071310,GO:0071345,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097447,GO:0097458,GO:0120025,GO:0120038,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1903311,GO:1903312,GO:1903313,GO:1903426,GO:1903427,GO:1904406,GO:1990904,GO:2000112,GO:2000113,GO:2000377,GO:2000378,GO:2000628	-	ko:K13210	-	-	-	-	ko00000,ko03019,ko03041	-	-	-	DUF1897,KH_1
k59_664605_1	1304885.AUEY01000003_gene496	5.88e-16	70.1	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,42VC4@68525|delta/epsilon subdivisions,2WRDM@28221|Deltaproteobacteria,2MKVE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Rubredoxin	rub	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k59_664605_2	1267535.KB906767_gene4945	9.63e-48	156.0	COG0251@1|root,COG0251@2|Bacteria,3Y5DN@57723|Acidobacteria,2JN2R@204432|Acidobacteriia	204432|Acidobacteriia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
k59_704853_1	247490.KSU1_C1433	3.66e-09	53.9	2ERQY@1|root,33JA6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_901159_2	717772.THIAE_02875	7.08e-13	69.3	COG1595@1|root,COG1595@2|Bacteria,1N34V@1224|Proteobacteria,1SA4Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_155269_1	570967.JMLV01000008_gene1415	4.02e-48	165.0	COG0683@1|root,COG0683@2|Bacteria,1N1MX@1224|Proteobacteria,2TSIX@28211|Alphaproteobacteria,2JRGW@204441|Rhodospirillales	204441|Rhodospirillales	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_155313_1	1121106.JQKB01000003_gene2522	1.71e-43	147.0	COG1522@1|root,COG1522@2|Bacteria,1RI7R@1224|Proteobacteria,2U9CC@28211|Alphaproteobacteria,2JTN8@204441|Rhodospirillales	204441|Rhodospirillales	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
k59_1135628_1	913865.DOT_2612	5.61e-68	225.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_1095922_2	305900.GV64_05075	6.63e-19	88.2	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,1XMWY@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_76880_1	1163409.UUA_16563	1.71e-42	158.0	COG1257@1|root,COG1577@1|root,COG1257@2|Bacteria,COG1577@2|Bacteria,1MXVE@1224|Proteobacteria,1RS9R@1236|Gammaproteobacteria,1X8RF@135614|Xanthomonadales	135614|Xanthomonadales	I	Hydroxymethylglutaryl-coenzyme A reductase	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N,HMG-CoA_red
k59_939103_1	1128421.JAGA01000001_gene2213	2.49e-90	278.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
k59_939107_1	1493511.A0A0E3G4R7_9CAUD	1.31e-49	174.0	4QB40@10239|Viruses,4QPWY@28883|Caudovirales,4QHVQ@10662|Myoviridae	10662|Myoviridae	S	nucleotide binding	-	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016032,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019058,GO:0019079,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0039686,GO:0039693,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044403,GO:0044419,GO:0046483,GO:0051704,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	-	-	-	-	-	-	-	-	-	-	-
k59_76935_1	1121918.ARWE01000001_gene1462	1.83e-36	135.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
k59_194316_1	582899.Hden_2710	4.04e-56	184.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2TT42@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_38352_1	1366050.N234_10795	3.45e-70	238.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2VNDM@28216|Betaproteobacteria,1KBX2@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
k59_664775_1	32051.SynWH7803_1665	8.86e-22	94.0	COG0477@1|root,COG0477@2|Bacteria,1GHTH@1117|Cyanobacteria,1GZ9J@1129|Synechococcus	1117|Cyanobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	Sugar_tr
k59_509223_1	1123518.ARWI01000001_gene1847	3.97e-31	125.0	COG2133@1|root,COG2373@1|root,COG2133@2|Bacteria,COG2373@2|Bacteria,1R65J@1224|Proteobacteria,1RYQV@1236|Gammaproteobacteria,461V8@72273|Thiotrichales	72273|Thiotrichales	G	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_194328_1	1121405.dsmv_0309	3.49e-62	199.0	COG1082@1|root,COG1082@2|Bacteria,1N95R@1224|Proteobacteria,42RAA@68525|delta/epsilon subdivisions,2WN55@28221|Deltaproteobacteria,2MJEW@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_744108_1	1229909.NSED_09885	2.53e-22	92.8	COG0177@1|root,arCOG00459@2157|Archaea,41SFM@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
k59_1135730_1	1304885.AUEY01000041_gene3688	9.09e-76	249.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,2MHW1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
k59_1135736_1	1118055.CAGU01000026_gene165	2.84e-67	214.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,22G2E@1570339|Peptoniphilaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k59_744131_1	314285.KT71_12625	8.07e-60	199.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RY52@1236|Gammaproteobacteria,1J7GW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_705090_1	589924.Ferp_0086	9.17e-25	102.0	COG0574@1|root,arCOG01114@2157|Archaea,2XVIT@28890|Euryarchaeota	28890|Euryarchaeota	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
k59_1096096_1	27679.XP_010327842.1	5.36e-87	279.0	KOG3792@1|root,KOG3792@2759|Eukaryota,39SGY@33154|Opisthokonta,3BBQY@33208|Metazoa,3D2GF@33213|Bilateria,486T1@7711|Chordata,498R9@7742|Vertebrata,3JBUS@40674|Mammalia,35IQ2@314146|Euarchontoglires,4MF3X@9443|Primates	33208|Metazoa	K	Interleukin enhancer binding factor 3	ILF3	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0003723,GO:0003725,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005739,GO:0006355,GO:0006417,GO:0006464,GO:0006468,GO:0006479,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008213,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016310,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043900,GO:0043901,GO:0043903,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045069,GO:0045071,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048525,GO:0050789,GO:0050792,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1903900,GO:1903901,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K13090	-	-	-	-	ko00000,ko03041	-	-	-	DZF,dsrm
k59_155472_1	482537.XP_008586179.1	3.13e-159	450.0	KOG0118@1|root,KOG0118@2759|Eukaryota,39QQW@33154|Opisthokonta,3BCXK@33208|Metazoa,3CV8H@33213|Bilateria,487J5@7711|Chordata,48YFY@7742|Vertebrata,3J6F6@40674|Mammalia,359ZK@314146|Euarchontoglires	33208|Metazoa	A	deaminase binding	HNRNPC	GO:0000375,GO:0000377,GO:0000398,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003729,GO:0003730,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005697,GO:0005737,GO:0005829,GO:0005856,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0008380,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010639,GO:0015629,GO:0016070,GO:0016071,GO:0019219,GO:0019222,GO:0019899,GO:0019904,GO:0030234,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0031974,GO:0031981,GO:0032204,GO:0032205,GO:0032210,GO:0032211,GO:0032991,GO:0033043,GO:0033044,GO:0034641,GO:0042802,GO:0043021,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043487,GO:0043488,GO:0043489,GO:0044092,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0044877,GO:0045120,GO:0045934,GO:0046483,GO:0048255,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051052,GO:0051053,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0061013,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070034,GO:0070935,GO:0071013,GO:0071704,GO:0080090,GO:0090304,GO:0090365,GO:0090367,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1902369,GO:1902373,GO:1902494,GO:1903311,GO:1903312,GO:1904356,GO:1904357,GO:1990247,GO:1990826,GO:1990827,GO:1990904,GO:2000112,GO:2000113,GO:2000278,GO:2000279,GO:2001251	-	ko:K12884,ko:K12895	ko03040,map03040	-	-	-	ko00000,ko00001,ko03041	-	-	-	RRM_1
k59_1096115_1	589873.EP13_06485	5.13e-24	99.4	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,464XH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0714 MoxR-like ATPases	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1096115_2	1249627.D779_1447	7.84e-44	155.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1WWS2@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_744197_1	485915.Dret_0523	4.35e-65	207.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,42MPM@68525|delta/epsilon subdivisions,2WKPX@28221|Deltaproteobacteria,2M9C4@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
k59_744197_2	1036674.A28LD_0145	1.43e-09	58.2	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,2QFSS@267893|Idiomarinaceae	1236|Gammaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_664936_1	1380394.JADL01000010_gene4366	5.42e-36	139.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2TQV5@28211|Alphaproteobacteria,2JPTZ@204441|Rhodospirillales	204441|Rhodospirillales	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
k59_469678_1	67593.Physo133120	7.72e-28	117.0	COG1167@1|root,KOG0634@2759|Eukaryota,3QDHQ@4776|Peronosporales	4776|Peronosporales	E	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,DapB_C,DapB_N
k59_77112_1	519989.ECTPHS_01709	2.03e-41	147.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria,1WXKK@135613|Chromatiales	135613|Chromatiales	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_38532_1	314278.NB231_08132	5.22e-113	360.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_861662_1	384765.SIAM614_02726	4.91e-26	108.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2TQP6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein related to deoxyribodipyrimidine photolyase	phrB	GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
k59_77177_1	933262.AXAM01000052_gene2002	3.05e-61	192.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2WMPD@28221|Deltaproteobacteria,2MJFM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_38625_1	1123240.ATVO01000003_gene167	5.14e-21	90.1	COG1414@1|root,COG1414@2|Bacteria,1QYTM@1224|Proteobacteria,2U04P@28211|Alphaproteobacteria,2K2VC@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix isocitrate lyase regulation	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
k59_38625_2	1408422.JHYF01000002_gene2274	3.01e-21	89.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,36J2N@31979|Clostridiaceae	186801|Clostridia	O	AhpC TSA family	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_861731_1	318167.Sfri_3725	1.99e-31	122.0	COG0583@1|root,COG0583@2|Bacteria,1R46P@1224|Proteobacteria,1S061@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1096368_1	944481.JAFP01000001_gene616	5.11e-71	233.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,2M6Q5@213113|Desulfurellales	28221|Deltaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_155787_1	1232410.KI421422_gene2071	8.48e-72	239.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,43S73@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_77326_1	1304885.AUEY01000036_gene2243	1.87e-23	95.5	COG1014@1|root,COG1014@2|Bacteria,1RBZA@1224|Proteobacteria,42QT3@68525|delta/epsilon subdivisions,2X6H9@28221|Deltaproteobacteria,2MJ4W@213118|Desulfobacterales	28221|Deltaproteobacteria	C	indolepyruvate ferredoxin oxidoreductase, beta subunit	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
k59_77326_2	411477.PARMER_01810	3.01e-17	82.0	COG1541@1|root,COG1541@2|Bacteria,4NGRR@976|Bacteroidetes,2FMB4@200643|Bacteroidia,22WWM@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_179036_1	360094.PXO_04542	1.75e-40	142.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1X3Z0@135614|Xanthomonadales	135614|Xanthomonadales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_179036_2	1123253.AUBD01000005_gene141	2.57e-52	176.0	COG1988@1|root,COG1988@2|Bacteria,1QK5N@1224|Proteobacteria,1S0MU@1236|Gammaproteobacteria,1X507@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
k59_21775_1	1125863.JAFN01000001_gene3086	1.34e-42	151.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_844916_1	519989.ECTPHS_06482	2.21e-85	276.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales	135613|Chromatiales	U	type IV pilus secretin PilQ	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_179050_1	222534.KB893721_gene972	9.47e-30	114.0	COG1024@1|root,COG1024@2|Bacteria,2HJKZ@201174|Actinobacteria,4EUKX@85013|Frankiales	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_220045_1	1122197.ATWI01000008_gene2680	9.27e-21	94.0	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,1S5IS@1236|Gammaproteobacteria,46B06@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_335665_2	745411.B3C1_00880	2.5e-77	242.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,1J5E5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_21828_1	985665.HPL003_11685	6.9e-30	119.0	COG0673@1|root,COG0673@2|Bacteria,1UZ84@1239|Firmicutes,4HE3W@91061|Bacilli,26VRV@186822|Paenibacillaceae	91061|Bacilli	S	dehydrogenases and related proteins	mmyG	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_418575_1	497964.CfE428DRAFT_0179	1.7e-72	234.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_610516_1	1118235.CAJH01000022_gene1443	3.13e-31	118.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1X393@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_727773_1	438753.AZC_0985	2.92e-89	277.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,3EZ37@335928|Xanthobacteraceae	28211|Alphaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_1006822_1	1117647.M5M_10800	9.93e-80	248.0	COG3637@1|root,COG3637@2|Bacteria,1PXDF@1224|Proteobacteria,1TC33@1236|Gammaproteobacteria,1JBGY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1119455_1	439235.Dalk_1208	7.31e-102	315.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria,2MIMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_884347_1	439235.Dalk_1361	4.76e-97	298.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,2MHTM@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_1043662_1	85643.Tmz1t_3892	8.38e-88	275.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,2VZHX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_492644_1	630626.EBL_c10080	5.22e-70	238.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
k59_688591_1	1535422.ND16A_2677	8.06e-62	207.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,2Q5Z8@267889|Colwelliaceae	1236|Gammaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt_3	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_139321_1	266264.Rmet_4133	1.88e-83	256.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,1K3BP@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM Transketolase central region	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_492662_1	518766.Rmar_1656	8.09e-73	241.0	COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1FIKN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	2.7.2.4,4.1.1.20	ko:K00928,ko:K12526	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00451,R00480	RC00002,RC00043,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_375357_1	2903.EOD28678	4.56e-32	125.0	COG1577@1|root,KOG1511@2759|Eukaryota	2759|Eukaryota	I	mevalonate kinase activity	mvk-1	GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006066,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006694,GO:0006695,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016126,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653	2.7.1.36,5.4.2.12	ko:K00869,ko:K15633	ko00010,ko00260,ko00680,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04146,map00010,map00260,map00680,map00900,map01100,map01110,map01120,map01130,map01200,map01230,map04146	M00001,M00002,M00003,M00095	R01518,R02245	RC00002,RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_1158447_1	690850.Desaf_0355	4.14e-82	269.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M9AP@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_21913_1	382245.ASA_2105	8.2e-10	58.2	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1Y48B@135624|Aeromonadales	135624|Aeromonadales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_21913_2	1033739.CAEU01000044_gene686	1.88e-37	134.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli,26E87@186818|Planococcaceae	91061|Bacilli	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
k59_922615_1	1028800.RG540_PA10390	2.19e-41	147.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,4BDDJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_922621_1	1125863.JAFN01000001_gene1857	5.3e-36	138.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_648732_1	96561.Dole_2001	6.14e-74	236.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42M9N@68525|delta/epsilon subdivisions,2WIZR@28221|Deltaproteobacteria,2MHKG@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_963064_1	504472.Slin_3723	6.37e-95	292.0	2DDHA@1|root,2ZI3C@2|Bacteria,4P22R@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1119557_1	1397528.Q671_14960	1.31e-66	215.0	COG3677@1|root,COG3677@2|Bacteria,1NUTK@1224|Proteobacteria,1S11R@1236|Gammaproteobacteria,1XS39@135619|Oceanospirillales	135619|Oceanospirillales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_492717_1	1121004.ATVC01000071_gene1165	1.95e-32	125.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,2KU4J@206351|Neisseriales	206351|Neisseriales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
k59_375429_1	426355.Mrad2831_2666	5.04e-11	66.2	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria,1JSA6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_375429_2	1500893.JQNB01000001_gene1150	3.88e-31	120.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1X3KZ@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
k59_60840_1	637389.Acaty_c2013	3.46e-87	270.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,2NDR0@225057|Acidithiobacillales	225057|Acidithiobacillales	H	DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
k59_963099_2	1280001.BAOA01000115_gene124	3.04e-29	110.0	COG0645@1|root,COG0645@2|Bacteria,1N1S8@1224|Proteobacteria,1SEDC@1236|Gammaproteobacteria,1XXSN@135623|Vibrionales	135623|Vibrionales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
k59_1079497_1	1417296.U879_08090	7.68e-111	323.0	COG1150@1|root,COG1150@2|Bacteria,1R874@1224|Proteobacteria,2U3QM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_9
k59_648766_1	1042377.AFPJ01000020_gene2041	2.26e-28	125.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	DctA-YdbH,Peptidase_S74
k59_1198060_1	1323663.AROI01000020_gene714	2.37e-07	56.6	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,1S3A6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Periplasmic protein TonB, links inner and outer membranes	tonB3	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_533708_1	1123057.P872_04760	1.57e-34	137.0	COG3291@1|root,COG5498@1|root,COG3291@2|Bacteria,COG5498@2|Bacteria,4PPR2@976|Bacteroidetes,47YQN@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_804964_1	439235.Dalk_4801	3.23e-95	289.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,43B8Z@68525|delta/epsilon subdivisions,2X6NB@28221|Deltaproteobacteria,2MPI8@213118|Desulfobacterales	1224|Proteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_804970_1	595494.Tola_2200	4.43e-39	141.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1Y3ZJ@135624|Aeromonadales	135624|Aeromonadales	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_922691_1	570952.ATVH01000018_gene3351	1.95e-75	244.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2TRDD@28211|Alphaproteobacteria,2JQ00@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_1241175_1	247490.KSU1_D0425	0.000645	45.4	COG2199@1|root,COG2227@1|root,COG2227@2|Bacteria,COG3706@2|Bacteria,2J2MA@203682|Planctomycetes	203682|Planctomycetes	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_1241175_2	880072.Desac_0837	1.59e-103	307.0	COG0685@1|root,COG0685@2|Bacteria,1RBND@1224|Proteobacteria,42QTG@68525|delta/epsilon subdivisions,2WN5D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
k59_884510_1	1158762.KB898047_gene573	6.32e-50	162.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,1WX50@135613|Chromatiales	135613|Chromatiales	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k59_884510_2	225937.HP15_2624	3.37e-05	45.8	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,465HT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0733 Na -dependent transporters of the SNF family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_1119628_1	765910.MARPU_07590	1.2e-59	203.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1WWKZ@135613|Chromatiales	135613|Chromatiales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
k59_610690_2	314285.KT71_15496	4.81e-38	130.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1J6K6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_60888_1	243233.MCA1437	1.59e-67	220.0	COG1922@1|root,COG2148@1|root,COG1922@2|Bacteria,COG2148@2|Bacteria,1N1HD@1224|Proteobacteria,1RP6P@1236|Gammaproteobacteria,1XFRP@135618|Methylococcales	135618|Methylococcales	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
k59_845164_1	981384.AEYW01000005_gene3029	1.91e-10	65.5	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4NB9A@97050|Ruegeria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_16,TPR_19
k59_297406_1	886377.Murru_3302	6.04e-05	46.6	COG1396@1|root,COG1680@1|root,COG3296@1|root,COG1396@2|Bacteria,COG1680@2|Bacteria,COG3296@2|Bacteria,4NG6Z@976|Bacteroidetes,1HZC5@117743|Flavobacteriia	976|Bacteroidetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF4870,HTH_3
k59_1007058_1	1151292.QEW_1559	2.54e-31	122.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,25RFG@186804|Peptostreptococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_688761_1	1121104.AQXH01000001_gene1400	2.49e-32	127.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1IWTY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_610708_1	933262.AXAM01000031_gene3021	3.74e-81	249.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2MIPC@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_297425_1	469615.FGAG_01442	8.37e-12	72.4	COG0845@1|root,COG0845@2|Bacteria,379M2@32066|Fusobacteria	32066|Fusobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_492811_1	1121015.N789_13360	3.78e-110	330.0	COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1X4GC@135614|Xanthomonadales	135614|Xanthomonadales	E	Cystathionine beta-synthase	cysB	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
k59_963182_1	342610.Patl_3740	3.02e-09	62.8	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,2Q1KI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
k59_101917_1	880072.Desac_2841	4.44e-38	135.0	COG2963@1|root,COG2963@2|Bacteria,1NDY6@1224|Proteobacteria,42VHR@68525|delta/epsilon subdivisions,2WSES@28221|Deltaproteobacteria,2MS3D@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_1043840_1	1255043.TVNIR_3629	9.78e-25	100.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,1S0KH@1236|Gammaproteobacteria,1WX4D@135613|Chromatiales	135613|Chromatiales	O	PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_1119689_1	9606.ENSP00000354665	3.95e-69	211.0	2C1NJ@1|root,2S2Q2@2759|Eukaryota,3A3DS@33154|Opisthokonta,3BS83@33208|Metazoa,3D7UJ@33213|Bilateria,48ESN@7711|Chordata,49BMT@7742|Vertebrata,3JH1Y@40674|Mammalia,35QT2@314146|Euarchontoglires,4MP1D@9443|Primates,4MXF4@9604|Hominidae	33208|Metazoa	C	NADH dehydrogenase (ubiquinone) activity	ND6	GO:0000302,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008150,GO:0009410,GO:0009636,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010257,GO:0014070,GO:0016020,GO:0016043,GO:0019866,GO:0022607,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032981,GO:0033108,GO:0034622,GO:0035094,GO:0042220,GO:0042221,GO:0042493,GO:0042542,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043279,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0060359,GO:0065003,GO:0071840,GO:0072347,GO:1901698,GO:1901700	1.6.5.3	ko:K03884	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q3
k59_1158632_1	742766.HMPREF9455_04152	1.14e-66	214.0	COG2801@1|root,COG2801@2|Bacteria,4NHJD@976|Bacteroidetes,2FQH2@200643|Bacteroidia	976|Bacteroidetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_3
k59_179327_1	1487921.DP68_13115	2.92e-06	53.5	COG3012@1|root,COG3012@2|Bacteria,1V9F3@1239|Firmicutes,24MI8@186801|Clostridia,36RXR@31979|Clostridiaceae	186801|Clostridia	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
k59_648874_1	1121405.dsmv_3053	1.03e-67	234.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2MI3P@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_727979_1	9606.ENSP00000356574	7.64e-124	373.0	KOG1731@1|root,KOG1731@2759|Eukaryota,38EPD@33154|Opisthokonta,3BAIN@33208|Metazoa,3CR62@33213|Bilateria,48319@7711|Chordata,48ZQF@7742|Vertebrata,3J3XS@40674|Mammalia,35C3T@314146|Euarchontoglires,4MBQZ@9443|Primates,4N30R@9604|Hominidae	33208|Metazoa	D	thiol oxidase activity	QSOX1	GO:0000003,GO:0000139,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002576,GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005788,GO:0005794,GO:0006457,GO:0006464,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010506,GO:0010507,GO:0012505,GO:0016020,GO:0016021,GO:0016192,GO:0016241,GO:0016242,GO:0016491,GO:0016667,GO:0016670,GO:0016853,GO:0016860,GO:0016864,GO:0016971,GO:0016972,GO:0019222,GO:0019538,GO:0030141,GO:0030173,GO:0031090,GO:0031091,GO:0031093,GO:0031224,GO:0031228,GO:0031300,GO:0031301,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0031984,GO:0032501,GO:0032504,GO:0032940,GO:0034774,GO:0034975,GO:0035580,GO:0036211,GO:0036230,GO:0042119,GO:0042581,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045171,GO:0045321,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0055114,GO:0060205,GO:0065007,GO:0070013,GO:0070062,GO:0070820,GO:0071704,GO:0097708,GO:0098588,GO:0098791,GO:0099503,GO:0140096,GO:1901564,GO:1903561,GO:1904724	1.8.3.2	ko:K10758	-	-	-	-	ko00000,ko01000	-	-	-	Evr1_Alr,Thioredoxin
k59_101941_1	1304885.AUEY01000006_gene753	1.93e-93	291.0	COG4191@1|root,COG4191@2|Bacteria,1P0U1@1224|Proteobacteria,42PTP@68525|delta/epsilon subdivisions,2WJ8U@28221|Deltaproteobacteria,2MIQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_648878_1	1121403.AUCV01000013_gene3901	3.06e-71	224.0	COG0765@1|root,COG0765@2|Bacteria,1R4RU@1224|Proteobacteria,42PW7@68525|delta/epsilon subdivisions,2WK9J@28221|Deltaproteobacteria,2MJID@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
k59_1007150_1	224914.BMEII0748	6.62e-168	477.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TSEI@28211|Alphaproteobacteria,1J21P@118882|Brucellaceae	28211|Alphaproteobacteria	C	2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal	bkdA1	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoDH_E1alpha_N
k59_335982_1	316067.Geob_2986	1.84e-34	136.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
k59_297523_1	1123242.JH636434_gene3744	3.07e-10	65.9	COG1574@1|root,COG1574@2|Bacteria,2IXY4@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_730347_3	187272.Mlg_1327	4.13e-31	120.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,1WXR0@135613|Chromatiales	135613|Chromatiales	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
k59_651449_1	10042.XP_006974957.1	3.83e-138	426.0	COG5181@1|root,KOG0213@2759|Eukaryota,38D0T@33154|Opisthokonta,3BDRI@33208|Metazoa,3CS7G@33213|Bilateria,485QU@7711|Chordata,490W1@7742|Vertebrata,3JB83@40674|Mammalia,35RK4@314146|Euarchontoglires,4Q8M5@9989|Rodentia	33208|Metazoa	A	Splicing factor 3B subunit 1	SF3B1	GO:0000245,GO:0000375,GO:0000377,GO:0000398,GO:0000785,GO:0001701,GO:0001824,GO:0001825,GO:0003002,GO:0003674,GO:0003676,GO:0003682,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005684,GO:0005686,GO:0005689,GO:0005694,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0007275,GO:0007389,GO:0008150,GO:0008152,GO:0008380,GO:0009653,GO:0009790,GO:0009792,GO:0009892,GO:0009893,GO:0009952,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016363,GO:0016604,GO:0016607,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030532,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0034399,GO:0034622,GO:0034641,GO:0034693,GO:0040029,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0045815,GO:0046483,GO:0048518,GO:0048519,GO:0048646,GO:0048856,GO:0050789,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0071004,GO:0071005,GO:0071010,GO:0071011,GO:0071013,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097525,GO:0120114,GO:1901360,GO:1901363,GO:1902494,GO:1990904	-	ko:K12828	ko03040,map03040	M00352	-	-	ko00000,ko00001,ko00002,ko03036,ko03041	-	-	-	SF3b1
k59_807567_1	706587.Desti_1831	5.47e-65	206.0	COG1802@1|root,COG1802@2|Bacteria,1MWG2@1224|Proteobacteria,42P4Y@68525|delta/epsilon subdivisions,2WQX9@28221|Deltaproteobacteria,2MQNT@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	GntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_807567_2	1125863.JAFN01000001_gene1231	9.95e-06	47.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,42QAD@68525|delta/epsilon subdivisions,2WK5V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_142169_1	335543.Sfum_2411	3.55e-97	293.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MR9A@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_63607_1	765910.MARPU_14815	6.49e-76	236.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,1RNDX@1236|Gammaproteobacteria,1WW21@135613|Chromatiales	135613|Chromatiales	M	UTP-glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_378489_1	1121405.dsmv_3409	1.06e-45	157.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2MHYY@213118|Desulfobacterales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
k59_1082393_2	378806.STAUR_0336	1.37e-64	216.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42R6X@68525|delta/epsilon subdivisions,2WMY9@28221|Deltaproteobacteria,2Z18Z@29|Myxococcales	28221|Deltaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_422595_1	247634.GPB2148_876	2.93e-86	271.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J85H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
k59_338834_2	314278.NB231_12686	4.13e-10	62.0	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1WZ55@135613|Chromatiales	135613|Chromatiales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_181764_1	880073.Calab_0821	8.04e-48	168.0	COG1972@1|root,COG1972@2|Bacteria,2NQR4@2323|unclassified Bacteria	2|Bacteria	F	Na+ dependent nucleoside transporter C-terminus	yeiM	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k59_315133_1	880072.Desac_1949	1.14e-82	275.0	COG2197@1|root,COG2203@1|root,COG4191@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MRI2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Signal transduction response regulator, receiver domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg,dCache_1,sCache_2
k59_432706_1	391595.RLO149_c028230	2.21e-21	93.2	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,2P4RP@2433|Roseobacter	28211|Alphaproteobacteria	H	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
k59_1020397_2	314271.RB2654_16161	3.92e-17	77.8	COG5447@1|root,COG5447@2|Bacteria,1N1KU@1224|Proteobacteria,2UCBQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	GTP-binding protein Era	MA20_15690	-	-	-	-	-	-	-	-	-	-	-	DUF1491
k59_667808_1	1122214.AQWH01000039_gene4763	1.74e-99	305.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TTBA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_981283_2	717785.HYPMC_2989	1.03e-21	95.1	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,3N6B3@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_942136_1	1449350.OCH239_10385	4.96e-07	50.8	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,4KP3Q@93682|Roseivivax	28211|Alphaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
k59_942136_2	565045.NOR51B_1530	2e-60	198.0	COG0620@1|root,COG0620@2|Bacteria,1QJ82@1224|Proteobacteria,1TH64@1236|Gammaproteobacteria,1J9IH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	E COG0620 Methionine synthase II (cobalamin-independent)	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
k59_1059553_1	314285.KT71_17366	2.97e-101	312.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1J4H8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_550320_2	1123399.AQVE01000003_gene2075	7.95e-26	107.0	COG2885@1|root,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,1RP3K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	oprF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,OprF,TSP_3
k59_824627_1	51337.XP_004654111.1	3.67e-182	508.0	COG1358@1|root,KOG3166@2759|Eukaryota,38EEJ@33154|Opisthokonta,3BAKG@33208|Metazoa,3CY8U@33213|Bilateria,488QM@7711|Chordata,4938G@7742|Vertebrata,3J3ZM@40674|Mammalia,35GD4@314146|Euarchontoglires,4PTTN@9989|Rodentia	33208|Metazoa	J	60S ribosomal protein	RPL7A	GO:0000184,GO:0000470,GO:0000956,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005516,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009719,GO:0009892,GO:0009987,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015934,GO:0016020,GO:0016070,GO:0016071,GO:0016072,GO:0019222,GO:0019439,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0033036,GO:0033365,GO:0034470,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0042221,GO:0042254,GO:0042273,GO:0042788,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0070727,GO:0070887,GO:0070972,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1904400,GO:1904401,GO:1904587,GO:1904588,GO:1990904	-	ko:K02936	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03009,ko03011	-	-	-	Ribosomal_L7Ae
k59_471917_1	1500890.JQNL01000001_gene3113	8.75e-22	100.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales	135614|Xanthomonadales	Q	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,LTD
k59_1958_1	335543.Sfum_2104	7.51e-129	383.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WJXY@28221|Deltaproteobacteria,2MRE3@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	succinate dehydrogenase or fumarate reductase, flavoprotein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_667855_1	1125863.JAFN01000001_gene2321	1.9e-78	239.0	COG0778@1|root,COG0778@2|Bacteria,1RBBW@1224|Proteobacteria,42QWC@68525|delta/epsilon subdivisions,2WMVU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_119338_1	717785.HYPMC_0050	7.95e-30	125.0	COG1511@1|root,COG1511@2|Bacteria,1QY7Q@1224|Proteobacteria,2TXIQ@28211|Alphaproteobacteria,3N82W@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
k59_981323_1	686340.Metal_3221	9.84e-42	145.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1XEFC@135618|Methylococcales	135618|Methylococcales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_981323_2	187272.Mlg_1244	1.17e-14	72.8	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1WWE2@135613|Chromatiales	135613|Chromatiales	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_628676_1	1238182.C882_0578	4.53e-69	230.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,2JPC0@204441|Rhodospirillales	204441|Rhodospirillales	C	malic enzyme	dme	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
k59_824666_1	1255043.TVNIR_2072	1.36e-05	45.4	2A022@1|root,30N4C@2|Bacteria,1PU9F@1224|Proteobacteria,1SCMU@1236|Gammaproteobacteria,1WYYW@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF1840)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1840
k59_824666_2	1121937.AUHJ01000009_gene1567	6.5e-22	97.4	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464NX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_471940_1	203122.Sde_3255	9.35e-66	209.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,464HJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_1304	GHMP_kinases_C,GHMP_kinases_N
k59_1020456_1	712898.Pvag_1369	8.17e-38	138.0	COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,1RQNB@1236|Gammaproteobacteria,3VXXW@53335|Pantoea	1236|Gammaproteobacteria	O	Xanthine dehydrogenase accessory protein	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_589581_1	157783.LK03_09990	1.99e-62	194.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
k59_589581_2	247633.GP2143_00227	6.49e-37	128.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1J5P3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_746212_1	66875.JODY01000002_gene4919	1.68e-27	116.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_746213_1	1121904.ARBP01000003_gene6366	7.11e-91	276.0	COG3367@1|root,COG3367@2|Bacteria,4NGXN@976|Bacteroidetes,47NP1@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
k59_746219_1	1122137.AQXF01000005_gene1170	5.09e-70	216.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
k59_119372_1	1121434.AULY01000009_gene2266	4.54e-29	120.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2M8CQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg
k59_1059654_1	583355.Caka_1740	2.02e-12	67.8	2CAZH@1|root,2Z7RU@2|Bacteria,46V42@74201|Verrucomicrobia,3K7Z0@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
k59_1059655_2	500632.CLONEX_02815	0.000324	48.1	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_integrase
k59_511144_2	1458357.BG58_08165	2.41e-08	57.4	COG4923@1|root,COG4923@2|Bacteria,1MY1R@1224|Proteobacteria,2WBKP@28216|Betaproteobacteria,1K688@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
k59_667957_2	395964.KE386496_gene1667	4.69e-20	90.9	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2TRDC@28211|Alphaproteobacteria,3NA9I@45404|Beijerinckiaceae	28211|Alphaproteobacteria	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
k59_942271_1	1205680.CAKO01000035_gene197	1.21e-33	124.0	COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,2TQSM@28211|Alphaproteobacteria,2JQF9@204441|Rhodospirillales	204441|Rhodospirillales	S	Serine hydrolase involved in the detoxification of formaldehyde	-	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase
k59_942271_2	1004785.AMBLS11_14350	7.83e-69	218.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,4644Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	frmA	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_276126_2	1124780.ANNU01000017_gene1896	4.06e-88	272.0	COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,47KC8@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	-	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k59_824759_1	1266914.ATUK01000012_gene212	4.5e-63	207.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,1RYPW@1236|Gammaproteobacteria,1WXQI@135613|Chromatiales	135613|Chromatiales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k59_824759_2	870187.Thini_3774	2.81e-112	342.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,463NI@72273|Thiotrichales	72273|Thiotrichales	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2
k59_393748_1	748247.AZKH_0348	1.4e-05	49.7	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2VNUX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
k59_83250_1	1129794.C427_3481	1.91e-58	194.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,4659R@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Lytic murein transglycosylase	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_1219117_1	1510531.JQJJ01000009_gene869	3.75e-65	228.0	COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2TR1M@28211|Alphaproteobacteria,3JTFW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	MA20_19630	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
k59_1101618_1	96561.Dole_2797	2.24e-70	223.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2WJPN@28221|Deltaproteobacteria,2MICH@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Thiamine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
k59_4710_1	1211777.BN77_p10226	5.81e-118	351.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,4B9Q6@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_200367_1	1122137.AQXF01000002_gene195	6.39e-141	412.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_1062398_1	290397.Adeh_1787	7.07e-25	101.0	COG3184@1|root,COG3184@2|Bacteria,1N7UG@1224|Proteobacteria,42XKS@68525|delta/epsilon subdivisions,2WSZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2059)	-	-	-	ko:K09924	-	-	-	-	ko00000	-	-	-	DUF2059
k59_709526_1	335543.Sfum_1064	2.44e-60	192.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,42S2E@68525|delta/epsilon subdivisions,2WMT9@28221|Deltaproteobacteria,2MRV6@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Phosphoribosyl transferase domain	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
k59_396749_1	1167006.UWK_01333	8.3e-40	154.0	COG0834@1|root,COG2202@1|root,COG2204@1|root,COG4191@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MHXZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3,dCache_3
k59_317832_1	269799.Gmet_0007	6.34e-88	270.0	COG2801@1|root,COG2801@2|Bacteria,1NUYG@1224|Proteobacteria,42ZK0@68525|delta/epsilon subdivisions,2WUUJ@28221|Deltaproteobacteria,43URT@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
k59_944955_1	395493.BegalDRAFT_2462	5.18e-35	126.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678	-	ko:K02197	-	-	-	-	ko00000	-	-	iSSON_1240.SSON_2255	CcmE
k59_1062408_1	478741.JAFS01000002_gene793	5.06e-66	213.0	COG1861@1|root,COG1861@2|Bacteria,46UVT@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_474699_1	1121405.dsmv_0479	3.76e-186	528.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2MIHR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_278776_1	1121447.JONL01000002_gene1996	5.67e-57	191.0	COG4782@1|root,COG4782@2|Bacteria,1PSSD@1224|Proteobacteria,430S8@68525|delta/epsilon subdivisions,2WW3H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
k59_4771_2	742738.HMPREF9460_02120	4.49e-37	131.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,26997@186813|unclassified Clostridiales	186801|Clostridia	CQ	BMC	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
k59_357482_1	439235.Dalk_0092	1.26e-18	88.2	COG1413@1|root,COG2199@1|root,COG3899@1|root,COG1413@2|Bacteria,COG2199@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	cpeY	-	2.7.11.1,2.7.7.65	ko:K05385,ko:K12132,ko:K13590	ko00196,ko01100,ko04112,map00196,map01100,map04112	-	-	-	ko00000,ko00001,ko00194,ko01000,ko01001	-	-	-	AAA_16,EAL,GGDEF,Trans_reg_C
k59_827443_1	96561.Dole_0302	1.41e-103	311.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N9U@68525|delta/epsilon subdivisions,2WINY@28221|Deltaproteobacteria,2MHR0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	tmcB	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k59_317898_1	1121271.AUCM01000001_gene3676	6.18e-70	223.0	28I5I@1|root,2Z88W@2|Bacteria,1PQS9@1224|Proteobacteria,2TVF8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1219231_1	84531.JMTZ01000030_gene214	5.88e-98	306.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1X2Z8@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
k59_592382_1	335659.S23_18590	9.81e-99	299.0	COG4177@1|root,COG4177@2|Bacteria,1PAW4@1224|Proteobacteria,2U0EY@28211|Alphaproteobacteria,3JT01@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	MA20_02455	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1219247_1	748658.KB907312_gene1136	2.18e-11	61.2	COG2212@1|root,COG2212@2|Bacteria,1N7BC@1224|Proteobacteria	1224|Proteobacteria	P	Multisubunit Na H antiporter, MnhF subunit	mnhF	-	-	ko:K05563,ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
k59_1219247_2	1121939.L861_21705	3.25e-36	128.0	COG1863@1|root,COG1863@2|Bacteria,1RB2I@1224|Proteobacteria,1S4XR@1236|Gammaproteobacteria,1XMCA@135619|Oceanospirillales	135619|Oceanospirillales	P	COG1863 Multisubunit Na H antiporter, MnhE subunit	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
k59_984586_1	247633.GP2143_15086	3.86e-08	61.6	COG0557@1|root,COG0557@2|Bacteria,1R33Q@1224|Proteobacteria,1T62R@1236|Gammaproteobacteria,1J5FB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the RNR ribonuclease family	-	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
k59_788331_2	317025.Tcr_2157	3.5e-10	59.3	COG1416@1|root,COG1416@2|Bacteria,1RBQX@1224|Proteobacteria,1S983@1236|Gammaproteobacteria,4633S@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
k59_1180525_1	1296415.JACC01000012_gene418	1.53e-34	135.0	COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,1HWV6@117743|Flavobacteriia,2YGSG@290174|Aquimarina	976|Bacteroidetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_514273_1	439235.Dalk_2844	3.18e-71	236.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2MI3D@213118|Desulfobacterales	28221|Deltaproteobacteria	L	UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_905717_1	551275.KB899544_gene1459	2.58e-27	115.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,2VEV5@28211|Alphaproteobacteria,43ZGC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_317974_1	392499.Swit_0538	2.77e-25	104.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,2K2R1@204457|Sphingomonadales	204457|Sphingomonadales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
k59_652508_1	335284.Pcryo_1221	1.86e-53	187.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,3NIUX@468|Moraxellaceae	1236|Gammaproteobacteria	M	Gamma-glutamyltranspeptidase	ggt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	iAPECO1_1312.APECO1_3012,iECOK1_1307.ECOK1_3869,iECS88_1305.ECS88_3844,iECW_1372.ECW_m3706,iEKO11_1354.EKO11_0296,iETEC_1333.ETEC_3693,iUMN146_1321.UM146_17325,iUTI89_1310.UTI89_C3954,iWFL_1372.ECW_m3706	G_glu_transpept
k59_652508_2	1121374.KB891575_gene1549	1.86e-44	156.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	phosphate transporter	pitA	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_731453_1	335543.Sfum_0155	1.26e-85	261.0	COG1774@1|root,COG1774@2|Bacteria,1MZBX@1224|Proteobacteria,42NE3@68525|delta/epsilon subdivisions,2WK98@28221|Deltaproteobacteria,2MQEI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
k59_1046952_1	767817.Desgi_1352	3.7e-43	152.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,2609D@186807|Peptococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_539087_1	521000.PROVRETT_08083	1.34e-31	117.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,1S95T@1236|Gammaproteobacteria,3Z96C@586|Providencia	1236|Gammaproteobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_539087_2	1218076.BAYB01000014_gene3051	1.12e-12	67.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2VJYK@28216|Betaproteobacteria,1K220@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM beta-lactamase domain protein	baeB	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1162617_2	1379270.AUXF01000001_gene2522	2.15e-27	114.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria	2|Bacteria	M	UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	cphA	-	6.3.2.13,6.3.2.29,6.3.2.30	ko:K01928,ko:K03802	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
k59_849099_1	1120956.JHZK01000007_gene2921	2.66e-24	95.5	COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,2U9DZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	rhodanese-related sulfurtransferase	MA20_01310	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_301343_1	96561.Dole_1856	1.31e-129	393.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MIDR@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_106454_1	631362.Thi970DRAFT_04432	1.27e-20	90.9	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,1T2D1@1236|Gammaproteobacteria,1X28U@135613|Chromatiales	135613|Chromatiales	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger
k59_888498_1	1121413.JMKT01000001_gene1765	6.95e-24	104.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,42NI3@68525|delta/epsilon subdivisions,2WJ6P@28221|Deltaproteobacteria,2M856@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_262131_1	428125.CLOLEP_01448	3.01e-17	75.9	2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes,24K1H@186801|Clostridia,3WJW5@541000|Ruminococcaceae	186801|Clostridia	S	non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_731492_1	1121875.KB907546_gene2238	1.23e-93	284.0	COG1409@1|root,COG1409@2|Bacteria,4NFAP@976|Bacteroidetes,1I2DE@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PA14
k59_1245275_1	236097.ADG881_3060	1.65e-35	137.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1XHGC@135619|Oceanospirillales	135619|Oceanospirillales	CH	hydroxylase	ubiF	-	-	ko:K18800	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04987,R08768	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
k59_692640_1	1121448.DGI_2963	1.78e-67	233.0	COG0834@1|root,COG2202@1|root,COG3829@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,1NWNJ@1224|Proteobacteria,43BSA@68525|delta/epsilon subdivisions,2X860@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4
k59_849113_1	648757.Rvan_1660	1.15e-63	209.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TT2C@28211|Alphaproteobacteria,3N64E@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_424088_1	118161.KB235922_gene2731	6.08e-22	96.3	COG0398@1|root,COG0398@2|Bacteria,1G3R9@1117|Cyanobacteria,3VM6G@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
k59_770660_2	1380355.JNIJ01000006_gene3043	1.23e-52	178.0	COG1893@1|root,COG1893@2|Bacteria,1QMH8@1224|Proteobacteria,2TSGW@28211|Alphaproteobacteria,3JWCH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	MA20_00225	-	-	-	-	-	-	-	-	-	-	-	ApbA
k59_496698_1	675635.Psed_6208	2.97e-24	105.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4E8WS@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_143329_1	933262.AXAM01000078_gene1614	2.22e-64	198.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,42REM@68525|delta/epsilon subdivisions,2WNMG@28221|Deltaproteobacteria,2MJT7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
k59_1083527_1	1211115.ALIQ01000198_gene447	3.69e-76	236.0	COG0491@1|root,COG0491@2|Bacteria,1MUT2@1224|Proteobacteria,2TRG9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_614543_1	1379281.AVAG01000033_gene497	1.31e-35	130.0	COG0437@1|root,COG0437@2|Bacteria,1QMKB@1224|Proteobacteria,42MPX@68525|delta/epsilon subdivisions,2WIKF@28221|Deltaproteobacteria,2M9F3@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_11,Fer4_7,TAT_signal
k59_614543_2	1232437.KL662058_gene3970	3.9e-28	106.0	COG2864@1|root,COG2864@2|Bacteria,1QW0N@1224|Proteobacteria,43BQM@68525|delta/epsilon subdivisions,2X71P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_182755_1	1265313.HRUBRA_01979	5.04e-38	144.0	COG0591@1|root,COG0591@2|Bacteria,1R4VK@1224|Proteobacteria,1RQFS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	nanT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_1245319_1	65093.PCC7418_0604	2.36e-79	249.0	COG2873@1|root,COG2873@2|Bacteria,1G4EH@1117|Cyanobacteria	1117|Cyanobacteria	E	O-acetylhomoserine sulfhydrylase	met17	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_770711_1	644282.Deba_2183	2.18e-72	243.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_380118_1	95619.PM1_0221820	1.04e-22	89.7	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Cold shock	cspD	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006275,GO:0006355,GO:0006950,GO:0008150,GO:0008156,GO:0009266,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2000113,GO:2001141	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_25959_1	177437.HRM2_38430	1e-64	207.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2MI8N@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_655462_2	1348338.ADILRU_0556	1.47e-72	243.0	COG1257@1|root,COG1577@1|root,COG1257@2|Bacteria,COG1577@2|Bacteria,2IAQ7@201174|Actinobacteria,4FNK1@85023|Microbacteriaceae	201174|Actinobacteria	I	GHMP kinases C terminal	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_110213_1	1123073.KB899241_gene2999	1.26e-79	242.0	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,1T1KA@1236|Gammaproteobacteria,1X38R@135614|Xanthomonadales	135614|Xanthomonadales	F	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
k59_734445_1	1121937.AUHJ01000010_gene1754	1.26e-122	369.0	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,466JE@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase,HAD
k59_542516_2	1028805.GGC_1707	1.78e-09	57.4	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,1Y8EH@135625|Pasteurellales	135625|Pasteurellales	CO	Protein involved in disulfide oxidoreductase activity, electron carrier activity, oxidoreductase activity, protein disulfide oxidoreductase activity, cell redox homeostasis, cytochrome complex assembly and glycerol ether metabolic process	nrfX	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	Redoxin
k59_542528_1	1410634.JHVD01000008_gene33	1.41e-77	245.0	COG3033@1|root,COG3033@2|Bacteria,2GKH3@201174|Actinobacteria	201174|Actinobacteria	E	Tryptophanase	tpl	-	4.1.99.1,4.1.99.2	ko:K01667,ko:K01668	ko00350,ko00380,map00350,map00380	-	R00673,R00728	RC00209,RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
k59_67984_1	933262.AXAM01000100_gene3391	6.41e-65	220.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2MHSK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1126664_1	29073.XP_008686332.1	2.48e-33	132.0	COG5022@1|root,KOG0160@2759|Eukaryota,KOG0161@2759|Eukaryota,38CVC@33154|Opisthokonta,3BBPR@33208|Metazoa,3CSM1@33213|Bilateria,47ZWQ@7711|Chordata,48X1J@7742|Vertebrata,3J87I@40674|Mammalia,3EQ69@33554|Carnivora	33208|Metazoa	Z	Myosin, heavy chain 10	MYH10	GO:0000003,GO:0000146,GO:0000166,GO:0000278,GO:0000281,GO:0000902,GO:0000904,GO:0000910,GO:0001568,GO:0001654,GO:0001655,GO:0001667,GO:0001700,GO:0001701,GO:0001725,GO:0001736,GO:0001738,GO:0001745,GO:0001764,GO:0001778,GO:0001894,GO:0001944,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0002791,GO:0002793,GO:0003002,GO:0003006,GO:0003008,GO:0003012,GO:0003205,GO:0003279,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003774,GO:0003779,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005826,GO:0005829,GO:0005844,GO:0005856,GO:0005886,GO:0005903,GO:0005911,GO:0005938,GO:0006810,GO:0006887,GO:0006928,GO:0006929,GO:0006930,GO:0006935,GO:0006936,GO:0006950,GO:0006996,GO:0007009,GO:0007010,GO:0007015,GO:0007049,GO:0007097,GO:0007155,GO:0007163,GO:0007164,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007386,GO:0007389,GO:0007391,GO:0007392,GO:0007395,GO:0007399,GO:0007405,GO:0007409,GO:0007411,GO:0007417,GO:0007420,GO:0007423,GO:0007424,GO:0007431,GO:0007435,GO:0007442,GO:0007443,GO:0007444,GO:0007455,GO:0007472,GO:0007476,GO:0007494,GO:0007496,GO:0007507,GO:0007512,GO:0007552,GO:0007560,GO:0008092,GO:0008104,GO:0008144,GO:0008150,GO:0008258,GO:0008283,GO:0008356,GO:0008360,GO:0008544,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009798,GO:0009886,GO:0009887,GO:0009888,GO:0009913,GO:0009952,GO:0009987,GO:0010256,GO:0010631,GO:0010830,GO:0010927,GO:0014706,GO:0015629,GO:0016020,GO:0016043,GO:0016192,GO:0016318,GO:0016331,GO:0016459,GO:0016460,GO:0016461,GO:0016462,GO:0016477,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017022,GO:0017076,GO:0017111,GO:0017145,GO:0019953,GO:0021537,GO:0021549,GO:0021591,GO:0021592,GO:0021670,GO:0021678,GO:0021680,GO:0021695,GO:0022008,GO:0022037,GO:0022402,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022610,GO:0022612,GO:0030010,GO:0030016,GO:0030017,GO:0030018,GO:0030027,GO:0030029,GO:0030030,GO:0030031,GO:0030036,GO:0030048,GO:0030054,GO:0030154,GO:0030182,GO:0030239,GO:0030424,GO:0030425,GO:0030426,GO:0030427,GO:0030496,GO:0030554,GO:0030707,GO:0030855,GO:0030863,GO:0030864,GO:0030898,GO:0030900,GO:0030902,GO:0031032,GO:0031033,GO:0031034,GO:0031036,GO:0031038,GO:0031175,GO:0031252,GO:0031674,GO:0032027,GO:0032153,GO:0032154,GO:0032155,GO:0032432,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032940,GO:0032982,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033267,GO:0034613,GO:0034622,GO:0035017,GO:0035026,GO:0035051,GO:0035107,GO:0035114,GO:0035120,GO:0035150,GO:0035151,GO:0035152,GO:0035159,GO:0035214,GO:0035220,GO:0035239,GO:0035272,GO:0035277,GO:0035295,GO:0035315,GO:0035316,GO:0035317,GO:0035613,GO:0035639,GO:0035904,GO:0036094,GO:0036445,GO:0036477,GO:0040011,GO:0042060,GO:0042067,GO:0042221,GO:0042330,GO:0042335,GO:0042592,GO:0042623,GO:0042641,GO:0042692,GO:0042802,GO:0042995,GO:0043005,GO:0043009,GO:0043010,GO:0043025,GO:0043167,GO:0043168,GO:0043197,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043531,GO:0043933,GO:0044085,GO:0044291,GO:0044297,GO:0044309,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044877,GO:0045165,GO:0045177,GO:0045179,GO:0045185,GO:0045196,GO:0045200,GO:0045202,GO:0045214,GO:0045595,GO:0046663,GO:0046664,GO:0046903,GO:0046907,GO:0048027,GO:0048103,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048546,GO:0048563,GO:0048565,GO:0048569,GO:0048592,GO:0048598,GO:0048609,GO:0048619,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048738,GO:0048749,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0048871,GO:0050708,GO:0050714,GO:0050789,GO:0050793,GO:0050794,GO:0050808,GO:0050877,GO:0050885,GO:0050896,GO:0050905,GO:0051015,GO:0051017,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051128,GO:0051146,GO:0051147,GO:0051153,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051235,GO:0051259,GO:0051301,GO:0051640,GO:0051641,GO:0051647,GO:0051649,GO:0051651,GO:0051656,GO:0051674,GO:0051704,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055012,GO:0055013,GO:0055015,GO:0055057,GO:0055059,GO:0055123,GO:0060041,GO:0060142,GO:0060249,GO:0060289,GO:0060322,GO:0060429,GO:0060537,GO:0060541,GO:0060562,GO:0060571,GO:0060840,GO:0060972,GO:0060976,GO:0061024,GO:0061061,GO:0061326,GO:0061333,GO:0061351,GO:0061525,GO:0061564,GO:0061572,GO:0061640,GO:0065003,GO:0065007,GO:0065008,GO:0070201,GO:0070650,GO:0070727,GO:0070925,GO:0070938,GO:0070986,GO:0071214,GO:0071260,GO:0071496,GO:0071840,GO:0071944,GO:0072001,GO:0072002,GO:0072089,GO:0072358,GO:0072359,GO:0090066,GO:0090087,GO:0090130,GO:0090132,GO:0090596,GO:0097159,GO:0097367,GO:0097435,GO:0097447,GO:0097458,GO:0097485,GO:0097513,GO:0097517,GO:0098590,GO:0098722,GO:0098794,GO:0098862,GO:0098885,GO:0099010,GO:0099080,GO:0099081,GO:0099512,GO:0099563,GO:0099568,GO:0099738,GO:0104004,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:1901265,GO:1901363,GO:1901739,GO:1903047,GO:1903530,GO:1903532,GO:1904951,GO:1990904	2.7.12.1	ko:K10352,ko:K17751,ko:K18669	ko04111,ko04260,ko04261,ko04530,ko05416,map04111,map04260,map04261,map04530,map05416	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04147,ko04812	-	-	-	IQ,Myosin_N,Myosin_head,Myosin_tail_1
k59_67999_1	335543.Sfum_1999	1.04e-97	301.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WJXY@28221|Deltaproteobacteria,2MQTE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_383796_1	880072.Desac_1201	8.03e-33	117.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WNNV@28221|Deltaproteobacteria,2MQDB@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_383796_2	335543.Sfum_0199	1.75e-46	154.0	COG0838@1|root,COG0838@2|Bacteria,1PPP3@1224|Proteobacteria,42VF4@68525|delta/epsilon subdivisions,2WRIV@28221|Deltaproteobacteria,2MQKR@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_655552_1	52598.EE36_07398	2.67e-32	122.0	2C3PP@1|root,2Z954@2|Bacteria,1MXGR@1224|Proteobacteria,2TS01@28211|Alphaproteobacteria,3ZV03@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Branched-chain amino acid aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_891611_1	1121403.AUCV01000007_gene1244	6.17e-80	261.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MHRD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_695635_1	247633.GP2143_04178	1.36e-88	276.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,1RRDF@1236|Gammaproteobacteria,1JBTR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	nylA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
k59_891630_1	439235.Dalk_3863	3.21e-97	293.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2MI9F@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bamN	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_1205503_1	1121405.dsmv_0392	1.87e-36	135.0	COG0394@1|root,COG0655@1|root,COG0394@2|Bacteria,COG0655@2|Bacteria,1NANP@1224|Proteobacteria,42Q16@68525|delta/epsilon subdivisions,2WIJ7@28221|Deltaproteobacteria,2MIC1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,LMWPc
k59_1205503_2	391624.OIHEL45_18831	1.08e-19	83.2	COG2358@1|root,COG2358@2|Bacteria,1NSZ5@1224|Proteobacteria,2U3NZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	transport system periplasmic component	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_851951_1	351160.RRC170	4.66e-06	47.8	COG0778@1|root,arCOG00288@2157|Archaea,2XYGC@28890|Euryarchaeota,2NAUV@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
k59_851951_2	1125971.ASJB01000043_gene3218	7.32e-09	60.5	COG2234@1|root,COG2234@2|Bacteria,2GIT0@201174|Actinobacteria,4DY8W@85010|Pseudonocardiales	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_1049459_1	1279017.AQYJ01000021_gene2902	2.36e-64	206.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,464EU@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0714 MoxR-like ATPases	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_499928_1	857293.CAAU_0401	2.29e-45	170.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,36FZW@31979|Clostridiaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	aor	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS09915	AFOR_C,AFOR_N
k59_383861_1	658187.LDG_6212	3.31e-84	261.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1JDF8@118969|Legionellales	118969|Legionellales	C	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	ICL
k59_68061_1	504472.Slin_2662	2.79e-72	228.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,4NJ32@976|Bacteroidetes,47TE9@768503|Cytophagia	976|Bacteroidetes	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
k59_1166073_1	1223523.H340_23011	2.21e-39	142.0	COG3485@1|root,COG3485@2|Bacteria,2GMGM@201174|Actinobacteria	201174|Actinobacteria	Q	protocatechuate 3,4-dioxygenase beta subunit	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
k59_228022_1	402777.KB235903_gene1953	2.73e-08	57.4	COG1028@1|root,COG1028@2|Bacteria,1G0MD@1117|Cyanobacteria,1H8AU@1150|Oscillatoriales	1117|Cyanobacteria	IQ	with different specificities (related to short-chain alcohol	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_228022_2	1038860.AXAP01000148_gene4496	1.1e-05	47.8	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
k59_970816_2	1461580.CCAS010000025_gene2537	2.1e-08	62.4	COG1388@1|root,COG3858@1|root,COG4932@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,COG4932@2|Bacteria,1TQK2@1239|Firmicutes,4HCVX@91061|Bacilli,1ZDSG@1386|Bacillus	91061|Bacilli	M	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM
k59_383913_1	118797.XP_007468721.1	1.18e-96	293.0	COG5176@1|root,KOG1588@2759|Eukaryota,39M3H@33154|Opisthokonta,3BJ08@33208|Metazoa,3CSKQ@33213|Bilateria,484JE@7711|Chordata,49023@7742|Vertebrata,3J2YJ@40674|Mammalia,4IZKY@91561|Cetartiodactyla	33208|Metazoa	A	KH domain-containing, RNA-binding, signal transduction-associated protein 1 isoform	KHDRBS1	GO:0000003,GO:0000086,GO:0000278,GO:0000375,GO:0000377,GO:0000398,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006355,GO:0006396,GO:0006397,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0007049,GO:0007050,GO:0007154,GO:0007165,GO:0007166,GO:0007276,GO:0007283,GO:0008143,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0008283,GO:0008380,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0017124,GO:0019219,GO:0019222,GO:0019904,GO:0019953,GO:0022402,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030674,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032239,GO:0032241,GO:0032268,GO:0032270,GO:0032386,GO:0032388,GO:0032501,GO:0032504,GO:0032879,GO:0032991,GO:0034248,GO:0034250,GO:0034641,GO:0035591,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043484,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044839,GO:0044877,GO:0045727,GO:0045786,GO:0045892,GO:0045934,GO:0045948,GO:0046483,GO:0046822,GO:0046824,GO:0046831,GO:0046833,GO:0048024,GO:0048232,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048609,GO:0050684,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051259,GO:0051704,GO:0051716,GO:0051726,GO:0060090,GO:0060255,GO:0060341,GO:0065003,GO:0065007,GO:0070013,GO:0070618,GO:0070717,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0098796,GO:0098797,GO:1901360,GO:1901363,GO:1902679,GO:1903047,GO:1903311,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13198,ko:K14942,ko:K17843	-	-	-	-	ko00000,ko03041	-	-	-	KH_1,Qua1,Sam68-YY
k59_228046_1	1396.DJ87_1873	3.83e-14	73.9	COG1680@1|root,COG1680@2|Bacteria,1TR9E@1239|Firmicutes,4HER8@91061|Bacilli,1ZFP7@1386|Bacillus	91061|Bacilli	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_228046_2	1461693.ATO10_10875	2.26e-28	110.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2TQS4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	cbbR1	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_617930_2	1517681.HW45_06325	5.2e-51	171.0	COG1028@1|root,COG1028@2|Bacteria,1MW4W@1224|Proteobacteria,1RRSA@1236|Gammaproteobacteria,1Y19X@135623|Vibrionales	135623|Vibrionales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_891731_1	869209.Tresu_1587	5.03e-19	90.1	COG4974@1|root,COG4974@2|Bacteria,2J5UZ@203691|Spirochaetes	203691|Spirochaetes	D	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_383932_1	1268239.PALB_14940	1.24e-31	127.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,1T241@1236|Gammaproteobacteria,2Q5IH@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	PFAM TonB-dependent receptor TonB-dependent receptor, plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_265467_1	63737.Npun_F3565	5.09e-54	192.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4251@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4251@2|Bacteria,1GQ9E@1117|Cyanobacteria,1HIP0@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
k59_1049547_1	1115515.EV102420_13_01740	4.05e-16	82.4	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,1RPTT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_655706_1	338963.Pcar_0359	3.55e-126	384.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,43S73@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_185473_1	1265505.ATUG01000002_gene1616	1.81e-100	320.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MIN8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_695751_2	1303518.CCALI_02843	6.83e-47	169.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_970862_1	349521.HCH_00541	2.07e-38	144.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1XHMP@135619|Oceanospirillales	135619|Oceanospirillales	T	Chemotaxis protein histidine kinase and related	chpA	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_212217_1	1123300.AUIN01000009_gene336	2.72e-26	110.0	COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli	91061|Bacilli	I	diphosphomevalonate decarboxylase	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_95490_1	1286631.X805_24390	3.66e-07	51.6	COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,2VMI9@28216|Betaproteobacteria,1KNFC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	TonB dependent receptor	bhuR	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,STN,TonB_dep_Rec
k59_95490_2	1255043.TVNIR_1650	3.38e-37	144.0	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,1RNS0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitrite reductase	nirS	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
k59_760407_1	400668.Mmwyl1_1128	1.53e-11	69.7	2BX7Z@1|root,2ZBYH@2|Bacteria,1RFFM@1224|Proteobacteria,1S5CF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	F plasmid transfer operon, TraF, protein	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
k59_721885_1	118797.XP_007453473.1	3.16e-160	454.0	KOG2190@1|root,KOG2190@2759|Eukaryota,38G1X@33154|Opisthokonta,3BX98@33208|Metazoa,3CY62@33213|Bilateria,480AI@7711|Chordata,49KZT@7742|Vertebrata,3J68M@40674|Mammalia,4J785@91561|Cetartiodactyla	33208|Metazoa	A	KH domain	PCBP1	GO:0000375,GO:0000377,GO:0000398,GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003700,GO:0003723,GO:0003729,GO:0003730,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008494,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016032,GO:0016070,GO:0016071,GO:0016604,GO:0016607,GO:0019058,GO:0019079,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0034641,GO:0035770,GO:0036464,GO:0039694,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045182,GO:0045727,GO:0045893,GO:0045935,GO:0045944,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0098847,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990904,GO:2000112,GO:2001141	-	ko:K12889	ko03040,ko04216,map03040,map04216	-	-	-	ko00000,ko00001,ko03019,ko03041	-	-	-	KH_1
k59_1073675_1	1396858.Q666_11260	1.05e-89	280.0	COG2771@1|root,COG4584@1|root,COG2771@2|Bacteria,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,468B0@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_24,rve
k59_54924_2	1121459.AQXE01000001_gene2765	2.57e-22	98.6	COG0749@1|root,COG0749@2|Bacteria,1P27P@1224|Proteobacteria,42YUP@68525|delta/epsilon subdivisions,2WTS1@28221|Deltaproteobacteria,2MAPB@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DNA polymerase A domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A
k59_251603_1	439235.Dalk_2556	6.56e-56	182.0	COG0685@1|root,COG0685@2|Bacteria,1MWQ3@1224|Proteobacteria,42PKP@68525|delta/epsilon subdivisions,2WK0A@28221|Deltaproteobacteria,2MIZB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
k59_762668_1	521719.ATXQ01000003_gene2149	2.12e-72	241.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,1YEC5@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Patatin-like phospholipase	plpD	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
k59_528199_2	933262.AXAM01000029_gene2731	4.24e-18	78.6	28NQ4@1|root,2ZBPU@2|Bacteria,1RCN1@1224|Proteobacteria,42QPC@68525|delta/epsilon subdivisions,2WMVS@28221|Deltaproteobacteria,2MJR9@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1001937_1	292415.Tbd_1375	1.98e-28	112.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_1075760_1	7668.SPU_012712-tr	6.09e-13	72.8	COG1999@1|root,KOG2792@2759|Eukaryota,38Q3U@33154|Opisthokonta,3BIA7@33208|Metazoa,3D295@33213|Bilateria	33208|Metazoa	C	cellular copper ion homeostasis	SCO1	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006091,GO:0006140,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006875,GO:0006878,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0008324,GO:0008535,GO:0009055,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010562,GO:0010605,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0016043,GO:0016491,GO:0016530,GO:0016531,GO:0016675,GO:0016676,GO:0017004,GO:0018995,GO:0019219,GO:0019220,GO:0019222,GO:0019725,GO:0019866,GO:0022607,GO:0022857,GO:0022890,GO:0022900,GO:0030003,GO:0030016,GO:0030162,GO:0030430,GO:0030808,GO:0030810,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031966,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032592,GO:0033108,GO:0033617,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0033650,GO:0033655,GO:0034220,GO:0034622,GO:0042176,GO:0042177,GO:0042592,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044190,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045861,GO:0045935,GO:0045937,GO:0045981,GO:0046872,GO:0046914,GO:0046916,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0055114,GO:0060255,GO:0061136,GO:0062012,GO:0062013,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0072492,GO:0080090,GO:0098573,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099080,GO:0099081,GO:0099512,GO:0140104,GO:1900371,GO:1900373,GO:1900542,GO:1900544,GO:1901799,GO:1902600,GO:1903050,GO:1903051,GO:1903362,GO:1903363,GO:1903578,GO:1903580,GO:2001169,GO:2001171	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_841225_1	1219084.AP014508_gene1682	1.76e-11	62.4	COG2316@1|root,COG2316@2|Bacteria,2GCT9@200918|Thermotogae	200918|Thermotogae	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
k59_841225_2	335543.Sfum_0463	1.18e-22	90.9	2ECCP@1|root,336AZ@2|Bacteria,1N9PN@1224|Proteobacteria,42W93@68525|delta/epsilon subdivisions,2WRXB@28221|Deltaproteobacteria,2MS3Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
k59_175907_2	1458275.AZ34_12110	2.46e-10	59.3	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VW1R@28216|Betaproteobacteria,4AEX6@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_684722_1	857087.Metme_3234	8.44e-33	126.0	COG2815@1|root,COG2815@2|Bacteria,1PGWR@1224|Proteobacteria,1SSGV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
k59_1154615_1	34839.XP_005410431.1	5.63e-114	335.0	KOG3001@1|root,KOG3001@2759|Eukaryota,38ZRW@33154|Opisthokonta,3BDPM@33208|Metazoa,3CZKY@33213|Bilateria,4838V@7711|Chordata,48W19@7742|Vertebrata,3JAZT@40674|Mammalia,35BY7@314146|Euarchontoglires,4PXE6@9989|Rodentia	33208|Metazoa	BK	Mortality factor 4-like protein 1	MORF4L1	GO:0000003,GO:0000118,GO:0000122,GO:0000123,GO:0000228,GO:0000414,GO:0000416,GO:0000724,GO:0000725,GO:0000785,GO:0000790,GO:0003006,GO:0003674,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006325,GO:0006338,GO:0006342,GO:0006355,GO:0006357,GO:0006464,GO:0006473,GO:0006475,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007059,GO:0007275,GO:0007276,GO:0007281,GO:0008150,GO:0008152,GO:0008283,GO:0009790,GO:0009792,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0016043,GO:0016458,GO:0016569,GO:0016570,GO:0016573,GO:0016575,GO:0016580,GO:0016604,GO:0016607,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019222,GO:0019538,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0030154,GO:0030234,GO:0030849,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033043,GO:0033044,GO:0033554,GO:0034641,GO:0034708,GO:0034728,GO:0035064,GO:0035097,GO:0035267,GO:0035601,GO:0036211,GO:0040029,GO:0042393,GO:0043044,GO:0043170,GO:0043189,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043486,GO:0043543,GO:0043933,GO:0043967,GO:0043968,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0045814,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0047485,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051304,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070013,GO:0070822,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090304,GO:0098732,GO:0098772,GO:0140030,GO:0140034,GO:1901360,GO:1901564,GO:1902275,GO:1902493,GO:1902494,GO:1902562,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1905269,GO:1990234,GO:2000112,GO:2000113,GO:2001141,GO:2001252	-	ko:K11339	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	MRG,Tudor-knot
k59_371634_1	1384056.N787_03745	7.31e-44	160.0	COG1461@1|root,COG1461@2|Bacteria,1NKAM@1224|Proteobacteria,1SHAC@1236|Gammaproteobacteria,1X3IB@135614|Xanthomonadales	135614|Xanthomonadales	S	Dak2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
k59_959095_1	697282.Mettu_2592	5.78e-102	306.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,1RYPY@1236|Gammaproteobacteria,1XETG@135618|Methylococcales	1236|Gammaproteobacteria	S	PFAM Transposase, IS801 IS1294	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_762715_1	192952.MM_1907	4.93e-62	197.0	COG1335@1|root,arCOG01943@2157|Archaea,2XWJY@28890|Euryarchaeota	28890|Euryarchaeota	Q	COG1335 Amidases related to nicotinamidase	entB1	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
k59_215053_1	1265505.ATUG01000001_gene4061	2.69e-40	143.0	COG0589@1|root,COG0745@1|root,COG0589@2|Bacteria,COG0745@2|Bacteria,1MZPD@1224|Proteobacteria,42U2Y@68525|delta/epsilon subdivisions,2WQ1I@28221|Deltaproteobacteria,2MQ25@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Usp
k59_413590_1	1121937.AUHJ01000006_gene2417	8.39e-60	196.0	COG2992@1|root,COG2992@2|Bacteria,1RD3U@1224|Proteobacteria,1S3RA@1236|Gammaproteobacteria,466Y0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	FlgJ-related protein	-	-	-	ko:K03796	-	-	-	-	ko00000	-	GH73	-	Glucosaminidase
k59_413593_1	670307.HYPDE_32708	7.25e-70	216.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2U592@28211|Alphaproteobacteria,3N6WR@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_371647_2	742823.HMPREF9465_00178	1.93e-127	367.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,4PQ57@995019|Sutterellaceae	28216|Betaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_959126_1	396588.Tgr7_1002	9.25e-76	242.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales	135613|Chromatiales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
k59_488858_2	1461694.ATO9_01585	7.59e-06	50.1	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TRET@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
k59_293419_1	472759.Nhal_2211	4.02e-25	105.0	COG1184@1|root,COG1184@2|Bacteria,1R0HY@1224|Proteobacteria,1T4I6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Initiation factor 2 subunit family	-	-	-	ko:K03680	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	IF-2B
k59_57182_1	269799.Gmet_0002	5.69e-67	218.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,43T1D@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_1040641_1	519989.ECTPHS_00909	6.28e-75	238.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1WWCI@135613|Chromatiales	135613|Chromatiales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_254063_1	314225.ELI_14900	1.07e-118	346.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2K2F6@204457|Sphingomonadales	204457|Sphingomonadales	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
k59_254063_2	395963.Bind_2882	1.15e-07	50.1	COG2963@1|root,COG2963@2|Bacteria,1RGZ5@1224|Proteobacteria,2UAIS@28211|Alphaproteobacteria,3NBSD@45404|Beijerinckiaceae	28211|Alphaproteobacteria	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_1154726_1	626418.bglu_2g21070	1.22e-08	58.5	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1K034@119060|Burkholderiaceae	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_762803_1	338966.Ppro_0129	2.03e-80	253.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,42N4S@68525|delta/epsilon subdivisions,2WJXX@28221|Deltaproteobacteria,43UK3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k59_215190_1	1279038.KB907337_gene649	3.41e-116	353.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,2TQXU@28211|Alphaproteobacteria,2JQHD@204441|Rhodospirillales	204441|Rhodospirillales	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	-	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
k59_293467_1	1267005.KB911256_gene1502	1.73e-52	180.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,3N8K5@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	Q	Flavin containing amine oxidoreductase	MA20_01895	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k59_449551_1	1122197.ATWI01000008_gene2888	3.07e-91	292.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,464Q5@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_331966_1	1159870.KB907784_gene1312	1.68e-19	92.8	COG0683@1|root,COG0683@2|Bacteria,1R6HB@1224|Proteobacteria,2VVCV@28216|Betaproteobacteria,3T5KY@506|Alcaligenaceae	28216|Betaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_1236579_1	1293054.HSACCH_01641	2.67e-107	325.0	COG3333@1|root,COG3333@2|Bacteria,1TPE7@1239|Firmicutes,24ZIP@186801|Clostridia	186801|Clostridia	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
k59_176156_1	96561.Dole_0097	2.16e-60	208.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,2MHW1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
k59_567193_1	1120956.JHZK01000013_gene2576	2.2e-55	185.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2TR20@28211|Alphaproteobacteria,1JPS2@119043|Rhodobiaceae	28211|Alphaproteobacteria	H	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
k59_1236586_1	1038860.AXAP01000006_gene6823	1.28e-88	271.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2TS3F@28211|Alphaproteobacteria,3JRDV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_528388_1	591158.SSMG_05546	8.59e-52	174.0	COG3386@1|root,COG3386@2|Bacteria,2GIW1@201174|Actinobacteria	201174|Actinobacteria	G	Strictosidine synthase	-	-	4.3.3.2	ko:K01757,ko:K10440	ko00901,ko01100,ko01110,ko02010,map00901,map01100,map01110,map02010	M00212	R03738	RC01072,RC01568	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	SGL,Str_synth
k59_254173_1	177437.HRM2_13710	2.18e-32	127.0	COG3829@1|root,COG4191@1|root,COG4585@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,COG4585@2|Bacteria,1QWMZ@1224|Proteobacteria,43BSW@68525|delta/epsilon subdivisions,2X73P@28221|Deltaproteobacteria,2MI1K@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PAS domain	-	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,PAS_9,dCache_1
k59_880702_2	1267535.KB906767_gene1343	9.44e-05	46.2	COG2085@1|root,COG2085@2|Bacteria,3Y5CN@57723|Acidobacteria,2JNMR@204432|Acidobacteriia	204432|Acidobacteriia	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
k59_254188_1	526225.Gobs_3374	2.86e-59	204.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria,4ETUQ@85013|Frankiales	201174|Actinobacteria	H	PFAM amine oxidase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
k59_684950_1	1121937.AUHJ01000009_gene1553	1.65e-97	300.0	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,1RNS0@1236|Gammaproteobacteria,46ADA@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Cytochrome D1 heme domain	nirS	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
k59_880724_1	247639.MGP2080_13273	5.89e-46	157.0	COG1028@1|root,COG1028@2|Bacteria,1N4J7@1224|Proteobacteria,1RQ0S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_567238_1	388739.RSK20926_12404	2.53e-11	62.8	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria,2P1H0@2433|Roseobacter	28211|Alphaproteobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
k59_567238_2	1121272.KB903289_gene4117	1.29e-31	112.0	2E9H4@1|root,333Q5@2|Bacteria,2HCJS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_528446_1	411902.CLOBOL_05025	1.77e-20	93.2	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia	186801|Clostridia	E	creatinase	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
k59_135942_1	396588.Tgr7_2545	2.97e-30	108.0	2ESGD@1|root,33K13@2|Bacteria,1NGAC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_135942_2	1255043.TVNIR_2084	8.69e-24	94.4	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,1S3WT@1236|Gammaproteobacteria,1WY7Z@135613|Chromatiales	135613|Chromatiales	KT	HD domain	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
k59_528456_1	1049564.TevJSym_ao00280	7.34e-79	261.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria	1224|Proteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_762923_1	768671.ThimaDRAFT_0873	2.82e-107	325.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGB@1236|Gammaproteobacteria,1X1MI@135613|Chromatiales	135613|Chromatiales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_1040755_1	324925.Ppha_0700	1.49e-40	152.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1FEG0@1090|Chlorobi	1090|Chlorobi	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
k59_449657_1	1121405.dsmv_2203	5.26e-95	286.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2MHXX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
k59_959312_1	37919.EP51_03910	1.19e-23	97.4	29VND@1|root,30H5P@2|Bacteria,2IG0Q@201174|Actinobacteria,4G95E@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_528474_1	1026882.MAMP_02814	4.08e-25	108.0	COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,45ZTT@72273|Thiotrichales	72273|Thiotrichales	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
k59_607044_1	335992.SAR11_1253	7.47e-89	284.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,4BPQB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the GcvT family	dmgdh2	-	1.5.8.4	ko:K00315	ko00260,ko01100,map00260,map01100	-	R01565	RC00181	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k59_332086_1	330214.NIDE0473	1.92e-37	136.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
k59_880775_1	1056820.KB900660_gene3576	6.12e-55	188.0	COG0591@1|root,COG0591@2|Bacteria,1R4VK@1224|Proteobacteria,1RQFS@1236|Gammaproteobacteria,2PPQW@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	Sodium:solute symporter family	nanT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
k59_254269_1	1515746.HR45_02310	1.64e-31	125.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria,2QB0B@267890|Shewanellaceae	1236|Gammaproteobacteria	G	Starch synthase catalytic domain protein	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008194,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	iSFV_1184.SFV_3438	Glyco_transf_5,Glycos_transf_1
k59_176250_1	633131.TR2A62_1421	1.36e-85	272.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_762980_1	338966.Ppro_2404	9.86e-39	139.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,43UK9@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_293647_1	247634.GPB2148_2748	4.49e-33	129.0	COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,1J575@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,TPR_16,TPR_8
k59_1116038_1	880072.Desac_2414	3.84e-12	68.6	COG2834@1|root,COG2834@2|Bacteria,1PDTV@1224|Proteobacteria,42TAB@68525|delta/epsilon subdivisions,2WPXY@28221|Deltaproteobacteria,2MSDK@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k59_413968_1	765910.MARPU_14080	2.94e-68	213.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1WX1Y@135613|Chromatiales	135613|Chromatiales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_567328_1	1211115.ALIQ01000198_gene463	2.61e-99	299.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,3NAJC@45404|Beijerinckiaceae	28211|Alphaproteobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_607101_1	573065.Astex_0582	6.71e-32	125.0	COG3391@1|root,COG3391@2|Bacteria,1NC58@1224|Proteobacteria,2UFDR@28211|Alphaproteobacteria,2KH9D@204458|Caulobacterales	204458|Caulobacterales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
k59_724374_1	522306.CAP2UW1_1327	3.31e-36	138.0	COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2VNFS@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,Fer4_7,FlpD
k59_215445_2	745014.OMB55_00004780	5.82e-20	89.7	COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,1S5ZZ@1236|Gammaproteobacteria,1J79H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	General secretion pathway protein J	gspJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
k59_1154963_1	1137799.GZ78_18720	2.02e-16	82.8	COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1XKGD@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	ko:K09938	-	-	-	-	ko00000	-	-	-	DUF2066
k59_293678_1	471874.PROSTU_00729	1.4e-30	111.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,3Z95I@586|Providencia	1236|Gammaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_129578_1	572265.HDEF_1845	8.82e-11	56.2	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,1SGC9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
k59_129578_2	545693.BMQ_0159	3.88e-89	268.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,1ZBYM@1386|Bacillus	91061|Bacilli	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
k59_286334_1	247634.GPB2148_334	1.32e-41	148.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,1J4M8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
k59_286334_2	713586.KB900536_gene610	1.26e-63	204.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1WWPK@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_834734_1	96561.Dole_2661	4.42e-32	121.0	COG0500@1|root,COG2226@2|Bacteria,1MW7J@1224|Proteobacteria,43BRY@68525|delta/epsilon subdivisions,2X72R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
k59_834734_2	690850.Desaf_0839	5.24e-15	73.2	2AVTU@1|root,31MME@2|Bacteria,1NQ7V@1224|Proteobacteria,42XCN@68525|delta/epsilon subdivisions,2WTFJ@28221|Deltaproteobacteria,2MFYI@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_521776_1	314285.KT71_06524	6.41e-26	111.0	COG4773@1|root,COG4773@2|Bacteria,1R3UW@1224|Proteobacteria,1T3KK@1236|Gammaproteobacteria,1JC1J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_717873_1	344747.PM8797T_25576	1.21e-67	231.0	COG0841@1|root,COG0841@2|Bacteria,2IY0K@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_834749_1	1121405.dsmv_0965	2.17e-75	247.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2MITA@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
k59_560527_1	323261.Noc_2120	3.36e-31	127.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1WVXH@135613|Chromatiales	135613|Chromatiales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
k59_1148216_1	335543.Sfum_1723	5.77e-51	179.0	COG0070@1|root,COG0493@1|root,COG1145@1|root,COG0070@2|Bacteria,COG0493@2|Bacteria,COG1145@2|Bacteria,1PBEZ@1224|Proteobacteria,42NFW@68525|delta/epsilon subdivisions,2WIQE@28221|Deltaproteobacteria,2MR5X@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	GXGXG motif	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,GXGXG,Pyr_redox_2,Pyr_redox_3,ThiF
k59_993320_1	1125863.JAFN01000001_gene530	7.81e-07	51.6	COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,42TNF@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
k59_993320_2	121225.PHUM025050-PA	4.01e-17	82.0	COG2759@1|root,KOG4230@2759|Eukaryota,38DB3@33154|Opisthokonta,3BBBH@33208|Metazoa,3CTTH@33213|Bilateria,41TMJ@6656|Arthropoda,3SJ7T@50557|Insecta,3E9Q2@33342|Paraneoptera	33208|Metazoa	H	Formate--tetrahydrofolate ligase	MTHFD1L	GO:0000166,GO:0001501,GO:0001838,GO:0001841,GO:0001843,GO:0002009,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0007275,GO:0007399,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009987,GO:0014020,GO:0015942,GO:0016053,GO:0016331,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0016999,GO:0017076,GO:0017144,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0021915,GO:0030554,GO:0031974,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035148,GO:0035239,GO:0035295,GO:0035639,GO:0036094,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0042802,GO:0042803,GO:0043009,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046983,GO:0048513,GO:0048562,GO:0048568,GO:0048598,GO:0048646,GO:0048701,GO:0048702,GO:0048703,GO:0048704,GO:0048705,GO:0048706,GO:0048729,GO:0048731,GO:0048856,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0060429,GO:0060562,GO:0060606,GO:0070013,GO:0071704,GO:0072175,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1904888	1.5.1.5,3.5.4.9,6.3.4.3	ko:K00288,ko:K13402	ko00670,ko01100,map00670,map01100	M00141	R00943,R01220,R01655	RC00026,RC00111,RC00202,RC00578	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FTHFS,THF_DHG_CYH,THF_DHG_CYH_C
k59_1228242_1	1499686.BN1079_03290	4.08e-72	227.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	recombinase XerD	xerD	GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1228290_1	9606.ENSP00000417864	7.76e-115	333.0	KOG2739@1|root,KOG2739@2759|Eukaryota,38PGI@33154|Opisthokonta,3BBPV@33208|Metazoa,3CYFG@33213|Bilateria,4884M@7711|Chordata,48V86@7742|Vertebrata,3JCFZ@40674|Mammalia,35BVA@314146|Euarchontoglires,4MEH8@9443|Primates,4MZ6K@9604|Hominidae	33208|Metazoa	D	histone binding	ANP32A	GO:0003674,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005829,GO:0005856,GO:0005875,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006338,GO:0006810,GO:0006913,GO:0006919,GO:0006996,GO:0007017,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0008017,GO:0008022,GO:0008092,GO:0008150,GO:0009892,GO:0009893,GO:0009894,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010639,GO:0010721,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0010975,GO:0010977,GO:0012505,GO:0015630,GO:0015631,GO:0016043,GO:0016363,GO:0019219,GO:0019222,GO:0019899,GO:0022008,GO:0022607,GO:0023052,GO:0030154,GO:0030162,GO:0031056,GO:0031057,GO:0031323,GO:0031324,GO:0031325,GO:0031329,GO:0031344,GO:0031345,GO:0031399,GO:0031400,GO:0031497,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033044,GO:0033157,GO:0034399,GO:0034622,GO:0034728,GO:0035065,GO:0035067,GO:0035556,GO:0042393,GO:0042981,GO:0043044,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043280,GO:0043281,GO:0043486,GO:0043487,GO:0043488,GO:0043933,GO:0044085,GO:0044093,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045862,GO:0046822,GO:0046824,GO:0046825,GO:0046827,GO:0046907,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050839,GO:0050896,GO:0051049,GO:0051050,GO:0051093,GO:0051128,GO:0051129,GO:0051169,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051276,GO:0051336,GO:0051345,GO:0051641,GO:0051649,GO:0051716,GO:0051960,GO:0051961,GO:0052547,GO:0052548,GO:0060255,GO:0060284,GO:0060341,GO:0061013,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070063,GO:0070201,GO:0071103,GO:0071824,GO:0071840,GO:0080090,GO:0090087,GO:0090316,GO:0120035,GO:1901983,GO:1901984,GO:1902275,GO:1903311,GO:1903827,GO:1903829,GO:1904951,GO:1905268,GO:2000026,GO:2000116,GO:2000756,GO:2000757,GO:2001056,GO:2001251	-	ko:K18646,ko:K18647	-	-	-	-	ko00000,ko03019,ko04147	-	-	-	LRR_4,LRR_9
k59_717939_1	1282876.BAOK01000001_gene1603	1.36e-27	108.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2UBUR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Protein conserved in bacteria	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
k59_12067_1	977880.RALTA_A0427	2.51e-36	137.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2VIZ7@28216|Betaproteobacteria,1K1XB@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.2,1.4.1.3	ko:K00260,ko:K00261	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_286453_1	335543.Sfum_1544	4.67e-38	132.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2WMP6@28221|Deltaproteobacteria,2MQF6@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_91267_1	342610.Patl_2993	8.22e-70	237.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,2Q0XA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_912835_1	1502852.FG94_03397	2.91e-68	220.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,2VRA9@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
k59_1109343_1	1173264.KI913949_gene498	2.56e-164	476.0	COG3328@1|root,COG3328@2|Bacteria,1G3YG@1117|Cyanobacteria,1HE7N@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_286479_1	999549.KI421513_gene2598	5.74e-56	180.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2TTE6@28211|Alphaproteobacteria,280N0@191028|Leisingera	28211|Alphaproteobacteria	I	Coenzyme A transferase	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_286479_2	398580.Dshi_1134	5.15e-53	171.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2TQS5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_286481_1	998674.ATTE01000001_gene267	4.87e-73	231.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,1SN1M@1236|Gammaproteobacteria,4639S@72273|Thiotrichales	72273|Thiotrichales	E	Homocysteine S-methyltransferase	-	-	2.1.1.5	ko:K00544	ko00260,ko00270,ko01100,map00260,map00270,map01100	-	R02821	RC00035,RC00496	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
k59_717989_1	1121405.dsmv_3255	3.81e-45	162.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2MIPH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_717997_2	425104.Ssed_3278	5.13e-29	112.0	COG1278@1|root,COG1463@1|root,COG1278@2|Bacteria,COG1463@2|Bacteria,1RHH6@1224|Proteobacteria,1S74Q@1236|Gammaproteobacteria,2QBT4@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	Protein of unknown function (DUF3465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3465
k59_717997_3	1280949.HAD_05790	3.33e-11	62.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2U787@28211|Alphaproteobacteria,43XTH@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Belongs to the ompA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA
k59_12139_1	525909.Afer_1021	8.18e-30	121.0	COG0437@1|root,COG5557@1|root,COG0437@2|Bacteria,COG5557@2|Bacteria,2H0W0@201174|Actinobacteria,4CNMM@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_756486_1	177439.DP2296	8.12e-18	82.8	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42MEY@68525|delta/epsilon subdivisions,2WM0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
k59_168915_1	641491.DND132_1272	6.93e-28	109.0	COG0778@1|root,COG4231@1|root,COG0778@2|Bacteria,COG4231@2|Bacteria,1R42D@1224|Proteobacteria,42Q57@68525|delta/epsilon subdivisions,2WNIW@28221|Deltaproteobacteria,2MB6I@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_9,Nitroreductase
k59_129783_1	1096546.WYO_0201	6.25e-52	185.0	28P6A@1|root,2ZC10@2|Bacteria,1RBZE@1224|Proteobacteria,2UQEG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1228426_1	1088869.GMO_23350	1.56e-56	186.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2TQQP@28211|Alphaproteobacteria,2JPSN@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k59_1148383_1	161156.JQKW01000008_gene398	3.02e-07	52.4	COG0546@1|root,COG0546@2|Bacteria,2GHIV@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_912901_1	879212.DespoDRAFT_00786	1.03e-128	383.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WIUM@28221|Deltaproteobacteria,2MI28@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_405124_1	1167006.UWK_01150	4.39e-102	317.0	COG2070@1|root,COG2070@2|Bacteria,1R8ZS@1224|Proteobacteria,42N1N@68525|delta/epsilon subdivisions,2WMIF@28221|Deltaproteobacteria,2MMMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1109437_1	1121406.JAEX01000005_gene2868	3.08e-92	285.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,42NI3@68525|delta/epsilon subdivisions,2WJ6P@28221|Deltaproteobacteria,2M856@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_208071_1	1238184.CM001792_gene171	1.53e-22	96.7	COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli,23ISS@182709|Oceanobacillus	91061|Bacilli	I	GHMP kinases N terminal domain	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_993600_1	1397284.AYMN01000107_gene3910	0.000123	47.8	COG0845@1|root,COG0845@2|Bacteria,1R3R4@1224|Proteobacteria,1RNSG@1236|Gammaproteobacteria,400AJ@613|Serratia	1236|Gammaproteobacteria	M	secretion protein	raxA	-	-	ko:K13408	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
k59_247610_2	1144932.ATTF01000006_gene78	1.08e-06	54.3	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2TQQN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
k59_835013_1	1304888.ATWF01000001_gene657	1.18e-22	97.1	COG0248@1|root,COG0248@2|Bacteria,2GFEH@200930|Deferribacteres	200930|Deferribacteres	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_835018_1	990285.RGCCGE502_25678	4.08e-36	139.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	cyaF2	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_16,TPR_19,TPR_2,TPR_8
k59_795555_1	745411.B3C1_06012	2.99e-35	134.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1J5VI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
k59_325645_1	1123274.KB899409_gene524	1.12e-16	80.1	COG0784@1|root,COG3852@1|root,COG0784@2|Bacteria,COG3852@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_8,PAS_9,Response_reg
k59_325645_2	96561.Dole_0427	6.42e-72	229.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1187977_1	29078.XP_008140249.1	0.0	883.0	KOG2192@1|root,KOG2192@2759|Eukaryota,39RQR@33154|Opisthokonta,3BEJ2@33208|Metazoa,3CWQZ@33213|Bilateria,489BY@7711|Chordata,492IQ@7742|Vertebrata,3J4E1@40674|Mammalia,4KSH4@9397|Chiroptera	33208|Metazoa	A	Heterogeneous nuclear ribonucleoprotein K	HNRNPK	GO:0000003,GO:0000122,GO:0000228,GO:0000375,GO:0000377,GO:0000398,GO:0000785,GO:0000790,GO:0000976,GO:0000977,GO:0000978,GO:0000981,GO:0000982,GO:0000987,GO:0001012,GO:0001067,GO:0001077,GO:0001101,GO:0001228,GO:0001541,GO:0001558,GO:0001654,GO:0001655,GO:0001678,GO:0001822,GO:0001889,GO:0002376,GO:0002520,GO:0002526,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003700,GO:0003723,GO:0003729,GO:0003730,GO:0005488,GO:0005515,GO:0005521,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005938,GO:0006139,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0006974,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007422,GO:0007423,GO:0007444,GO:0007446,GO:0007548,GO:0007568,GO:0008092,GO:0008134,GO:0008150,GO:0008152,GO:0008283,GO:0008380,GO:0008406,GO:0008585,GO:0009058,GO:0009059,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009790,GO:0009792,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010494,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010720,GO:0010869,GO:0010870,GO:0010941,GO:0010975,GO:0010976,GO:0010984,GO:0010988,GO:0014069,GO:0014070,GO:0014823,GO:0016070,GO:0016071,GO:0016604,GO:0016607,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019725,GO:0019899,GO:0019904,GO:0021537,GO:0021543,GO:0021549,GO:0021761,GO:0021766,GO:0021987,GO:0022008,GO:0022037,GO:0022414,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023056,GO:0030100,GO:0030154,GO:0030307,GO:0030323,GO:0030324,GO:0030424,GO:0030425,GO:0030628,GO:0030900,GO:0030902,GO:0031072,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031344,GO:0031346,GO:0031974,GO:0031981,GO:0032091,GO:0032279,GO:0032368,GO:0032501,GO:0032502,GO:0032774,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0032993,GO:0033119,GO:0033120,GO:0033267,GO:0033500,GO:0033554,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0035062,GO:0035107,GO:0035265,GO:0035295,GO:0035690,GO:0035770,GO:0036002,GO:0036464,GO:0036477,GO:0040007,GO:0040008,GO:0042221,GO:0042493,GO:0042592,GO:0042593,GO:0042802,GO:0042805,GO:0042981,GO:0042995,GO:0043005,GO:0043010,GO:0043021,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043197,GO:0043200,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043393,GO:0043434,GO:0043484,GO:0043565,GO:0043679,GO:0044092,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044306,GO:0044309,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044456,GO:0044463,GO:0044464,GO:0044877,GO:0045137,GO:0045165,GO:0045202,GO:0045472,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045714,GO:0045716,GO:0045807,GO:0045892,GO:0045893,GO:0045927,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046545,GO:0046660,GO:0046677,GO:0048024,GO:0048025,GO:0048167,GO:0048259,GO:0048260,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048538,GO:0048583,GO:0048589,GO:0048608,GO:0048638,GO:0048639,GO:0048699,GO:0048731,GO:0048732,GO:0048736,GO:0048856,GO:0048869,GO:0048878,GO:0050684,GO:0050686,GO:0050767,GO:0050769,GO:0050773,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050804,GO:0050806,GO:0050807,GO:0050896,GO:0051049,GO:0051050,GO:0051093,GO:0051094,GO:0051098,GO:0051100,GO:0051117,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0051960,GO:0051961,GO:0051962,GO:0055082,GO:0060255,GO:0060284,GO:0060322,GO:0060341,GO:0060429,GO:0060541,GO:0060548,GO:0060627,GO:0060688,GO:0060998,GO:0060999,GO:0061008,GO:0061458,GO:0061478,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070887,GO:0071013,GO:0071229,GO:0071230,GO:0071236,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071362,GO:0071375,GO:0071396,GO:0071407,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0072001,GO:0072367,GO:0072369,GO:0072752,GO:0080090,GO:0080134,GO:0080135,GO:0090128,GO:0090129,GO:0090304,GO:0097159,GO:0097305,GO:0097306,GO:0097327,GO:0097447,GO:0097458,GO:0097659,GO:0098793,GO:0098794,GO:0098984,GO:0099177,GO:0099568,GO:0099572,GO:0120025,GO:0120035,GO:0120038,GO:0140110,GO:0150034,GO:1900006,GO:1900271,GO:1900273,GO:1901355,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901796,GO:1902074,GO:1902165,GO:1902229,GO:1902253,GO:1902494,GO:1902531,GO:1902679,GO:1902680,GO:1903311,GO:1903312,GO:1903506,GO:1903507,GO:1903508,GO:1903827,GO:1903829,GO:1903859,GO:1903861,GO:1904321,GO:1904322,GO:1905952,GO:1990715,GO:1990829,GO:1990837,GO:1990904,GO:2000008,GO:2000010,GO:2000026,GO:2000112,GO:2000113,GO:2000172,GO:2000173,GO:2001020,GO:2001141,GO:2001233,GO:2001242	2.4.1.133	ko:K00733,ko:K12886	ko00532,ko00534,ko01100,ko03040,ko05168,ko05203,ko05206,map00532,map00534,map01100,map03040,map05168,map05203,map05206	M00057	R05926	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko03041	-	GT7	-	KH_1,ROKNT
k59_639239_1	396588.Tgr7_1129	5.82e-86	281.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWJ6@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_639242_1	1304875.JAFZ01000001_gene867	7.89e-47	168.0	COG1506@1|root,COG1506@2|Bacteria,3T9W7@508458|Synergistetes	508458|Synergistetes	E	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
k59_286649_1	472759.Nhal_0798	9.08e-80	257.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,1S4M3@1236|Gammaproteobacteria,1WWN6@135613|Chromatiales	135613|Chromatiales	E	Extracellular solute-binding protein, family 5	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k59_247666_1	398579.Spea_2953	5.55e-23	97.1	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,1RNSQ@1236|Gammaproteobacteria,2QBFQ@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Belongs to the group II decarboxylase family	gadB	GO:0003674,GO:0003824,GO:0004351,GO:0006082,GO:0006520,GO:0006536,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
k59_1228600_1	953739.SVEN_0694	7.04e-39	139.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1112670_1	96561.Dole_1776	8.03e-14	76.3	COG4191@1|root,COG4191@2|Bacteria,1R9AK@1224|Proteobacteria,42Q2G@68525|delta/epsilon subdivisions,2WM8Y@28221|Deltaproteobacteria,2MI84@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1112679_1	626939.HMPREF9443_00190	1.21e-19	81.3	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes	1239|Firmicutes	K	Cold shock	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_642224_1	266265.Bxe_A3010	6.83e-51	171.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2VKYJ@28216|Betaproteobacteria,1K3XV@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
k59_94764_1	1249480.B649_10490	4.51e-35	137.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2YMMJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	penicillin-binding protein	pbpA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_1191207_1	266834.SMc00477	7.32e-56	191.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TQNZ@28211|Alphaproteobacteria,4BMYI@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_998028_1	482537.XP_008590525.1	3.78e-126	359.0	COG0091@1|root,KOG3353@2759|Eukaryota,38H3J@33154|Opisthokonta,3BA3T@33208|Metazoa,3CT31@33213|Bilateria,486KF@7711|Chordata,4946S@7742|Vertebrata,3J7YP@40674|Mammalia,35BX7@314146|Euarchontoglires	33208|Metazoa	J	large ribosomal subunit rRNA binding	RPL17	GO:0000184,GO:0000956,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015934,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0050789,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060255,GO:0065007,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02880	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
k59_290148_2	1121374.KB891585_gene1876	1.15e-21	96.7	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_998034_1	640512.BC1003_1735	4.18e-32	130.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,1K2P2@119060|Burkholderiaceae	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
k59_211500_1	9555.ENSPANP00000019562	2.23e-109	319.0	KOG1755@1|root,KOG1755@2759|Eukaryota,3A0N9@33154|Opisthokonta,3BPAZ@33208|Metazoa,3D2SF@33213|Bilateria,48BJX@7711|Chordata,4981Z@7742|Vertebrata,3J7Y6@40674|Mammalia,35DXS@314146|Euarchontoglires,4M7P3@9443|Primates,369KK@314294|Cercopithecoidea	33208|Metazoa	Z	Belongs to the profilin family	PFN1	GO:0000166,GO:0000774,GO:0001838,GO:0001841,GO:0001843,GO:0002009,GO:0003674,GO:0003779,GO:0003785,GO:0005102,GO:0005488,GO:0005515,GO:0005543,GO:0005546,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005856,GO:0005938,GO:0006355,GO:0006357,GO:0006996,GO:0007010,GO:0007015,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0007399,GO:0008064,GO:0008092,GO:0008104,GO:0008150,GO:0008154,GO:0008289,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010632,GO:0010634,GO:0010638,GO:0010639,GO:0014020,GO:0016043,GO:0016055,GO:0016331,GO:0017016,GO:0017048,GO:0017076,GO:0019219,GO:0019222,GO:0019899,GO:0021915,GO:0022603,GO:0023052,GO:0030029,GO:0030036,GO:0030234,GO:0030334,GO:0030335,GO:0030554,GO:0030832,GO:0030833,GO:0030837,GO:0030838,GO:0031267,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031333,GO:0031334,GO:0031344,GO:0031346,GO:0031647,GO:0032231,GO:0032232,GO:0032233,GO:0032271,GO:0032272,GO:0032273,GO:0032501,GO:0032502,GO:0032507,GO:0032535,GO:0032781,GO:0032879,GO:0032956,GO:0032970,GO:0033036,GO:0033043,GO:0034613,GO:0035091,GO:0035148,GO:0035239,GO:0035295,GO:0035567,GO:0036094,GO:0040012,GO:0040017,GO:0042221,GO:0042989,GO:0042995,GO:0043005,GO:0043009,GO:0043085,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043254,GO:0043462,GO:0043900,GO:0043902,GO:0043903,GO:0044087,GO:0044089,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045185,GO:0045202,GO:0045893,GO:0045935,GO:0045944,GO:0046782,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048598,GO:0048646,GO:0048729,GO:0048731,GO:0048856,GO:0050434,GO:0050789,GO:0050790,GO:0050792,GO:0050793,GO:0050794,GO:0050821,GO:0050896,GO:0051020,GO:0051052,GO:0051054,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051235,GO:0051239,GO:0051240,GO:0051252,GO:0051254,GO:0051270,GO:0051272,GO:0051336,GO:0051345,GO:0051492,GO:0051493,GO:0051494,GO:0051495,GO:0051496,GO:0051497,GO:0051641,GO:0051651,GO:0051716,GO:0060071,GO:0060255,GO:0060429,GO:0060491,GO:0060562,GO:0060589,GO:0060590,GO:0060606,GO:0065007,GO:0065008,GO:0065009,GO:0070064,GO:0070727,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071840,GO:0071944,GO:0072175,GO:0080090,GO:0090066,GO:0090175,GO:0097159,GO:0097435,GO:0097458,GO:0098772,GO:0099568,GO:0110020,GO:0110053,GO:0120025,GO:0120032,GO:0120034,GO:0120035,GO:0198738,GO:1900027,GO:1900029,GO:1901265,GO:1901363,GO:1901981,GO:1902680,GO:1902903,GO:1902904,GO:1902905,GO:1902936,GO:1903506,GO:1903508,GO:1905114,GO:1905330,GO:2000026,GO:2000027,GO:2000112,GO:2000145,GO:2000147,GO:2001141	-	ko:K05759	ko04013,ko04015,ko04810,ko05131,ko05132,map04013,map04015,map04810,map05131,map05132	-	-	-	ko00000,ko00001,ko04131,ko04147,ko04812	-	-	-	Profilin
k59_1112719_1	384765.SIAM614_02596	1.66e-58	197.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_485827_1	948106.AWZT01000014_gene625	4.52e-66	228.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,1K1YU@119060|Burkholderiaceae	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_838273_1	335543.Sfum_1181	7.3e-41	149.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_1191227_1	760117.JN27_15815	3.1e-27	106.0	COG1846@1|root,COG1846@2|Bacteria,1NA1D@1224|Proteobacteria,2WAWK@28216|Betaproteobacteria,477NB@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
k59_525316_1	551789.ATVJ01000001_gene1473	6.2e-78	241.0	COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,2TQSM@28211|Alphaproteobacteria,43WC6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Serine hydrolase involved in the detoxification of formaldehyde	fghA	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase
k59_28187_1	4155.Migut.F02074.1.p	2.8e-36	138.0	COG0265@1|root,KOG1320@2759|Eukaryota,37P6K@33090|Viridiplantae,3G86S@35493|Streptophyta,44C7B@71274|asterids	35493|Streptophyta	O	Protease Do-like 10, mitochondrial	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_733869_1	265072.Mfla_0196	1.25e-36	134.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,2KM39@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_184652_2	1304865.JAGF01000001_gene738	2.88e-09	60.5	COG3677@1|root,COG3677@2|Bacteria,2IF2C@201174|Actinobacteria	201174|Actinobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_890816_1	1211114.ALIP01000097_gene10	1.38e-25	101.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1X4AM@135614|Xanthomonadales	135614|Xanthomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
k59_890816_2	69395.JQLZ01000002_gene1299	4.55e-10	61.2	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2U79T@28211|Alphaproteobacteria,2KGHI@204458|Caulobacterales	204458|Caulobacterales	G	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_382971_1	744980.TRICHSKD4_3106	4.37e-109	320.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	branched-chain amino acid	cysA	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_459623_1	1537715.JQFJ01000002_gene2146	2.59e-54	190.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,2K0RP@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_459625_1	889378.Spiaf_1726	2.64e-49	170.0	COG1226@1|root,COG1226@2|Bacteria,2J72E@203691|Spirochaetes	203691|Spirochaetes	P	TrkA-N domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
k59_733892_1	997346.HMPREF9374_3540	7.04e-70	223.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,27B4N@186824|Thermoactinomycetaceae	91061|Bacilli	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_303588_1	9986.ENSOCUP00000009787	4.32e-119	342.0	COG5045@1|root,KOG3344@2759|Eukaryota,3A3IE@33154|Opisthokonta,3BFX3@33208|Metazoa,3CSSU@33213|Bilateria,484AJ@7711|Chordata,48XAD@7742|Vertebrata,3JC1R@40674|Mammalia,35CB3@314146|Euarchontoglires	33208|Metazoa	J	ribosomal protein	RPS10	GO:0000028,GO:0000049,GO:0000184,GO:0000956,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007275,GO:0007568,GO:0008104,GO:0008150,GO:0008152,GO:0008340,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010259,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034655,GO:0042254,GO:0042255,GO:0042274,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0048856,GO:0050789,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0070727,GO:0070925,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071826,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02947	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S10_plectin
k59_1125949_1	1118235.CAJH01000043_gene2777	0.000275	46.2	COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,1X6WV@135614|Xanthomonadales	135614|Xanthomonadales	M	cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k59_1247146_1	9593.ENSGGOP00000026159	1.36e-102	298.0	COG0636@1|root,KOG3025@2759|Eukaryota,3A3YG@33154|Opisthokonta,3BQFS@33208|Metazoa,3D69R@33213|Bilateria,48E3Y@7711|Chordata,49B2J@7742|Vertebrata,3JGP4@40674|Mammalia,35PN0@314146|Euarchontoglires,4MJ3H@9443|Primates,4MUCF@9604|Hominidae	33208|Metazoa	C	ATP hydrolysis coupled proton transport	ATP5G3	GO:0000276,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005743,GO:0005753,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0007568,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009636,GO:0009987,GO:0010033,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016043,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0019866,GO:0019867,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032502,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042221,GO:0042407,GO:0042493,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0045471,GO:0046034,GO:0046390,GO:0046483,GO:0046677,GO:0046933,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0061024,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0097305,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098805,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1902600	-	ko:K02128	ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016	M00158	-	-	ko00000,ko00001,ko00002	3.A.2.1	-	-	ATP-synt_C
k59_694932_1	335543.Sfum_1613	1.7e-16	78.6	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2MQHR@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PP-loop family	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_694932_2	335543.Sfum_1766	7e-34	128.0	COG2896@1|root,COG2896@2|Bacteria,1MXMH@1224|Proteobacteria,42NTM@68525|delta/epsilon subdivisions,2WKIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_733898_1	384765.SIAM614_22967	1.8e-06	48.9	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	5-aminolevulinic acid synthase	hemA	-	2.3.1.37	ko:K00643	ko00260,ko00860,ko01100,ko01110,map00260,map00860,map01100,map01110	-	R00830	RC00004,RC02815	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_733905_2	96561.Dole_0908	4.83e-51	181.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,2MIC2@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
k59_427131_1	1247649.D560_3902	5.18e-44	157.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2VS3Y@28216|Betaproteobacteria,3T6MV@506|Alcaligenaceae	28216|Betaproteobacteria	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
k59_969972_1	1122194.AUHU01000002_gene2624	1.52e-06	49.3	COG1805@1|root,COG1805@2|Bacteria,1QTUU@1224|Proteobacteria,1RMGH@1236|Gammaproteobacteria,46504@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
k59_969972_2	857087.Metme_2630	2.38e-38	142.0	COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,1XDP1@135618|Methylococcales	135618|Methylococcales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_184697_1	550540.Fbal_1886	2.52e-48	168.0	COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,1RP9M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_851302_2	1110502.TMO_0669	1.2e-07	56.6	COG0025@1|root,COG0664@1|root,COG0025@2|Bacteria,COG0664@2|Bacteria,1MW5T@1224|Proteobacteria,2TSHB@28211|Alphaproteobacteria,2JQD0@204441|Rhodospirillales	204441|Rhodospirillales	PT	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,cNMP_binding
k59_342558_1	404589.Anae109_3411	4.62e-40	151.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria	1224|Proteobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
k59_303619_1	314285.KT71_17381	2.95e-38	137.0	2CG07@1|root,33ZSV@2|Bacteria,1NYDT@1224|Proteobacteria,1SPWB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2452)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2452
k59_1085804_1	1122137.AQXF01000002_gene190	1.86e-35	139.0	COG0803@1|root,COG0803@2|Bacteria,1MY4H@1224|Proteobacteria,2U4S8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
k59_1048845_1	765952.PUV_21460	5.74e-16	75.5	COG1028@1|root,COG1028@2|Bacteria,2JG7F@204428|Chlamydiae	204428|Chlamydiae	IQ	KR domain	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_1048845_2	1121028.ARQE01000007_gene3955	2.41e-09	58.5	COG2303@1|root,COG2303@2|Bacteria,1MUK2@1224|Proteobacteria,2U08V@28211|Alphaproteobacteria,2PKB3@255475|Aurantimonadaceae	28211|Alphaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
k59_1125987_1	160799.PBOR_27810	6.31e-56	190.0	COG0366@1|root,COG0366@2|Bacteria,1TR93@1239|Firmicutes,4HEKC@91061|Bacilli,26TSJ@186822|Paenibacillaceae	91061|Bacilli	G	Alpha amylase, catalytic domain	-	-	2.4.1.329	ko:K21350	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase
k59_1247178_1	880072.Desac_1087	4.55e-15	76.3	arCOG06116@1|root,30C51@2|Bacteria,1REWK@1224|Proteobacteria,42RFM@68525|delta/epsilon subdivisions,2WNYX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_733934_1	543728.Vapar_5845	2.31e-24	99.0	2F8F6@1|root,340TX@2|Bacteria,1R0U0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_733934_2	388399.SSE37_22265	4.58e-13	68.9	COG1804@1|root,COG1804@2|Bacteria,1R43P@1224|Proteobacteria,2U1WN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	5.4.1.3	ko:K14470	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R09283	RC02480	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
k59_810842_1	697282.Mettu_0764	7.22e-68	216.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1XE51@135618|Methylococcales	135618|Methylococcales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_617207_1	566466.NOR53_3413	0.000162	43.9	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
k59_577471_1	1202962.KB907150_gene1812	1.64e-107	323.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_1165174_1	984262.SGRA_0523	1.09e-55	187.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1IQ2Y@117747|Sphingobacteriia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
k59_1013425_1	670307.HYPDE_37173	2.72e-74	243.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,2U1SX@28211|Alphaproteobacteria,3N7RR@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_transp_aux
k59_577483_1	314278.NB231_01374	3.01e-106	323.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_890906_1	1049564.TevJSym_aq00560	1.2e-96	303.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1J4RW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA helicase	uvrD	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_851344_1	1122915.AUGY01000018_gene6241	6.59e-10	61.2	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4HCAR@91061|Bacilli,26QI0@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	deoR	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K05346	-	-	-	-	ko00000,ko03000	-	-	-	HTH_23,HTH_24,HTH_Crp_2,MarR_2,Sigma70_r4,Sugar-bind
k59_577496_1	935836.JAEL01000003_gene362	3.97e-07	56.6	COG1309@1|root,COG1309@2|Bacteria,1V0ZV@1239|Firmicutes,4HEVI@91061|Bacilli,1ZQCM@1386|Bacillus	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_810868_1	665942.HMPREF1022_03100	3.72e-18	77.0	COG1146@1|root,COG1146@2|Bacteria,1QWQ4@1224|Proteobacteria,43BUY@68525|delta/epsilon subdivisions,2X75X@28221|Deltaproteobacteria,2MHB0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
k59_890914_1	552811.Dehly_0140	4.44e-97	298.0	COG2070@1|root,COG2070@2|Bacteria	2|Bacteria	S	nitronate monooxygenase activity	ycf23	-	1.1.1.205,1.13.12.16	ko:K00088,ko:K00459	ko00230,ko00910,ko00983,ko01100,ko01110,map00230,map00910,map00983,map01100,map01110	M00050	R00025,R01130,R08240	RC00143,RC02207,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	DUF561,Glu_synthase,IMPDH,NMO
k59_67431_1	1121405.dsmv_3648	1.27e-84	255.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2WJ1Z@28221|Deltaproteobacteria,2MHWH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_810882_1	1384056.N787_10085	6.08e-21	97.1	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1X37J@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k59_890924_1	713586.KB900536_gene245	5.43e-87	260.0	COG0599@1|root,COG2146@1|root,COG0599@2|Bacteria,COG2146@2|Bacteria,1RCCG@1224|Proteobacteria	1224|Proteobacteria	P	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Rieske
k59_459767_1	582899.Hden_0691	1.92e-110	325.0	COG1148@1|root,COG1148@2|Bacteria,1R882@1224|Proteobacteria,2U526@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_oxidored,Pyr_redox_2
k59_1085882_1	9606.ENSP00000364935	4.86e-174	485.0	KOG1422@1|root,KOG1422@2759|Eukaryota,39TVS@33154|Opisthokonta,3BFU3@33208|Metazoa,3CSEA@33213|Bilateria,47ZMY@7711|Chordata,4913X@7742|Vertebrata,3JCGQ@40674|Mammalia,35EIK@314146|Euarchontoglires,4MGAF@9443|Primates,4N015@9604|Hominidae	33208|Metazoa	P	Glutathione S-transferase, N-terminal domain	CLIC1	GO:0003674,GO:0005215,GO:0005216,GO:0005244,GO:0005247,GO:0005253,GO:0005254,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005739,GO:0005903,GO:0006810,GO:0006811,GO:0006820,GO:0006821,GO:0007154,GO:0007165,GO:0008150,GO:0008308,GO:0008509,GO:0009987,GO:0012505,GO:0015075,GO:0015103,GO:0015108,GO:0015267,GO:0015318,GO:0015698,GO:0022803,GO:0022832,GO:0022836,GO:0022838,GO:0022839,GO:0022857,GO:0023052,GO:0030278,GO:0031967,GO:0031975,GO:0031982,GO:0034220,GO:0042391,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0043231,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045597,GO:0045667,GO:0045669,GO:0045778,GO:0048471,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051716,GO:0051881,GO:0055085,GO:0065007,GO:0065008,GO:0070062,GO:0098656,GO:0098660,GO:0098661,GO:0098862,GO:1902476,GO:1903561	-	ko:K05021	-	-	-	-	ko00000,ko04040,ko04147	1.A.12.1.2	-	-	GST_C_2,GST_N_2,GST_N_3
k59_264694_1	1499967.BAYZ01000048_gene2700	2.45e-79	249.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2,MFS_3
k59_67483_1	1487953.JMKF01000036_gene3256	1.6e-72	241.0	COG1452@1|root,COG1452@2|Bacteria,1G0TW@1117|Cyanobacteria,1H7RX@1150|Oscillatoriales	1117|Cyanobacteria	M	Mannosyl oligosaccharide glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
k59_890968_1	439235.Dalk_2281	5.8e-100	307.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42Z00@68525|delta/epsilon subdivisions,2WTI9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_184826_1	96561.Dole_0037	3.12e-69	225.0	COG0457@1|root,COG0457@2|Bacteria,1RKYJ@1224|Proteobacteria,42SSS@68525|delta/epsilon subdivisions,2WPW3@28221|Deltaproteobacteria,2MNI4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
k59_383165_1	1121405.dsmv_1683	5.38e-112	340.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,43BUE@68525|delta/epsilon subdivisions,2X75I@28221|Deltaproteobacteria,2MPKE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Conserved carboxylase domain	oadA	-	2.1.3.1,4.1.1.3,6.4.1.1	ko:K01571,ko:K01960,ko:K03416	ko00020,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00640,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344,R00353,R00930	RC00040,RC00097,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_577619_1	228405.HNE_0207	3.28e-40	144.0	COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,2UA3V@28211|Alphaproteobacteria,43XQ1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0046835,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_1247267_1	1392498.JQLH01000001_gene2495	5.32e-07	58.5	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia,2PGS6@252356|Maribacter	976|Bacteroidetes	M	Tricorn protease C1 domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
k59_67522_1	754477.Q7C_412	3.8e-58	202.0	COG2911@1|root,COG2911@2|Bacteria,1MW9V@1224|Proteobacteria,1S3FX@1236|Gammaproteobacteria,461VT@72273|Thiotrichales	72273|Thiotrichales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_184842_1	1133850.SHJG_8127	1.23e-52	196.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Beta-lactamase,Condensation,PP-binding
k59_1013537_1	67593.Physo141966	5.24e-32	128.0	COG3491@1|root,KOG0143@2759|Eukaryota,3QADR@4776|Peronosporales	4776|Peronosporales	Q	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
k59_1127775_2	1121439.dsat_0534	4.31e-21	91.3	COG1863@1|root,COG1863@2|Bacteria,1MZYJ@1224|Proteobacteria,42UQ9@68525|delta/epsilon subdivisions,2WQ8C@28221|Deltaproteobacteria,2MFZG@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Na+/H+ ion antiporter subunit	-	-	-	-	-	-	-	-	-	-	-	-	MNHE
k59_1127800_1	314285.KT71_02872	2.3e-11	64.7	2C06Y@1|root,32RKB@2|Bacteria,1N4F8@1224|Proteobacteria,1SBCD@1236|Gammaproteobacteria,1J887@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1127800_2	761193.Runsl_0607	3.11e-24	103.0	COG0591@1|root,COG0591@2|Bacteria,4NH7H@976|Bacteroidetes,47JA4@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K14387	ko04725,ko05231,map04725,map05231	-	-	-	ko00000,ko00001,ko02000	2.A.21,2.A.21.8	-	-	HD_4,SSF
k59_696736_1	309799.DICTH_0672	8.08e-71	229.0	COG0441@1|root,COG0441@2|Bacteria	2|Bacteria	J	threonyl-tRNA aminoacylation	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
k59_111442_1	879212.DespoDRAFT_02905	7.99e-96	291.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42MAQ@68525|delta/epsilon subdivisions,2WKK0@28221|Deltaproteobacteria,2MINE@213118|Desulfobacterales	28221|Deltaproteobacteria	E	transport system permease	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_429205_1	1049564.TevJSym_ak00930	1.7e-62	198.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,1J5G3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
k59_147440_1	9606.ENSP00000356548	5.12e-119	352.0	KOG2637@1|root,KOG2637@2759|Eukaryota,38FAZ@33154|Opisthokonta,3BAM5@33208|Metazoa,3CX91@33213|Bilateria,480BD@7711|Chordata,48Z2D@7742|Vertebrata,3J4WR@40674|Mammalia,35MVT@314146|Euarchontoglires,4MHSV@9443|Primates,4MY0U@9604|Hominidae	33208|Metazoa	U	Low temperature viability protein	LTV1	GO:0000054,GO:0000056,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005774,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006364,GO:0006396,GO:0006403,GO:0006405,GO:0006611,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0007049,GO:0008104,GO:0008150,GO:0008152,GO:0008361,GO:0009058,GO:0009059,GO:0009987,GO:0010008,GO:0010467,GO:0012505,GO:0015031,GO:0015833,GO:0015931,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0022402,GO:0022613,GO:0022626,GO:0022627,GO:0030684,GO:0030688,GO:0031090,GO:0031410,GO:0031503,GO:0031902,GO:0031974,GO:0031981,GO:0031982,GO:0032535,GO:0032991,GO:0033036,GO:0033750,GO:0034448,GO:0034470,GO:0034613,GO:0034641,GO:0034645,GO:0034660,GO:0042023,GO:0042254,GO:0042274,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044391,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044433,GO:0044437,GO:0044440,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044786,GO:0045184,GO:0045793,GO:0046483,GO:0046907,GO:0050657,GO:0050658,GO:0051168,GO:0051169,GO:0051179,GO:0051234,GO:0051236,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0071166,GO:0071426,GO:0071428,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0090066,GO:0090304,GO:0097708,GO:0098588,GO:0098796,GO:0098805,GO:1901360,GO:1901576,GO:1990904	-	ko:K14798	-	-	-	-	ko00000,ko03009	-	-	-	LTV
k59_266567_1	1278307.KB907057_gene2644	4.51e-115	343.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,2QJ5B@267894|Psychromonadaceae	1236|Gammaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1248853_1	876044.IMCC3088_2538	4.33e-15	75.9	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RYI9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_429212_1	1282362.AEAC466_16915	1.06e-35	133.0	COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2TT0S@28211|Alphaproteobacteria,2KJWR@204458|Caulobacterales	204458|Caulobacterales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
k59_501081_1	257310.BB4753	2.05e-36	134.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2W0AU@28216|Betaproteobacteria,3T582@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_1167240_1	933262.AXAM01000041_gene1892	8.69e-103	316.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MJ2X@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
k59_385004_1	911045.PSE_3737	7.1e-16	83.6	COG1289@1|root,COG1289@2|Bacteria	2|Bacteria	S	transmembrane transporter activity	VPA1578	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_812643_1	443143.GM18_1541	9.95e-26	110.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
k59_972001_1	1126627.BAWE01000004_gene2247	4.59e-47	169.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_8,TolB_N
k59_1127873_1	335543.Sfum_2550	1.93e-92	285.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WKEK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_696793_1	1121405.dsmv_2939	5.26e-75	234.0	COG2214@1|root,COG2214@2|Bacteria,1NW19@1224|Proteobacteria,43012@68525|delta/epsilon subdivisions,2WVBG@28221|Deltaproteobacteria,2MNIU@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_812655_1	1123400.KB904749_gene720	4.76e-39	146.0	COG1100@1|root,COG1100@2|Bacteria,1QXSV@1224|Proteobacteria,1S5FA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	50S ribosome-binding GTPase	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	DUF697,MMR_HSR1
k59_1248905_1	1122613.ATUP01000001_gene1765	3.24e-26	109.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,43X1H@69657|Hyphomonadaceae	28211|Alphaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1248905_2	629773.AORY01000002_gene1430	2.06e-44	148.0	COG3011@1|root,COG3011@2|Bacteria,1Q3II@1224|Proteobacteria,2UFWG@28211|Alphaproteobacteria,2K6D2@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
k59_461536_2	1042375.AFPL01000031_gene753	9.86e-06	47.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,464XP@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_812672_1	96561.Dole_2493	3.94e-117	348.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,2MHRT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
k59_873275_1	1123253.AUBD01000001_gene1873	1.86e-100	303.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,1RN0N@1236|Gammaproteobacteria,1X35A@135614|Xanthomonadales	135614|Xanthomonadales	C	oxidase, subunit II	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_bd_oxida_II
k59_717354_1	247490.KSU1_C1443	4.83e-07	55.1	COG1234@1|root,COG1234@2|Bacteria,2J27A@203682|Planctomycetes	203682|Planctomycetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_992511_1	1408224.SAMCCGM7_c5948	8.79e-84	258.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2U1C5@28211|Alphaproteobacteria,4BC24@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
k59_404164_1	443143.GM18_2764	6.4e-52	176.0	COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,42N43@68525|delta/epsilon subdivisions,2WM7N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Domain of unknown function (DUF1738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1738,Toprim_3
k59_246803_3	497965.Cyan7822_4871	8.95e-39	145.0	COG2199@1|root,COG3706@2|Bacteria,1G5G4@1117|Cyanobacteria	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_404186_1	566466.NOR53_2675	1.13e-65	213.0	COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,1RP9M@1236|Gammaproteobacteria,1J8KH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_11459_1	1279017.AQYJ01000027_gene1807	1.63e-16	79.3	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,46440@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_11459_2	382464.ABSI01000012_gene2198	6.31e-18	84.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C
k59_638467_1	631362.Thi970DRAFT_04518	2.33e-07	57.8	COG0501@1|root,COG0501@2|Bacteria,1R47C@1224|Proteobacteria,1RPRU@1236|Gammaproteobacteria,1X0GS@135613|Chromatiales	135613|Chromatiales	O	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_50677_1	439235.Dalk_2555	9.01e-81	243.0	COG0745@1|root,COG0789@1|root,COG0745@2|Bacteria,COG0789@2|Bacteria,1RD9E@1224|Proteobacteria,42PTZ@68525|delta/epsilon subdivisions,2WKZI@28221|Deltaproteobacteria,2MHNV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
k59_1032074_1	10042.XP_006982255.1	2.77e-191	538.0	KOG0118@1|root,KOG0118@2759|Eukaryota,39ST6@33154|Opisthokonta,3BA81@33208|Metazoa,3CRMB@33213|Bilateria,485HG@7711|Chordata,48V1Y@7742|Vertebrata,3J2S9@40674|Mammalia,35DS1@314146|Euarchontoglires,4PVA9@9989|Rodentia	33208|Metazoa	A	Heterogeneous nuclear ribonucleoproteins A2	HNRNPA2B1	GO:0000003,GO:0000122,GO:0000375,GO:0000377,GO:0000381,GO:0000398,GO:0000723,GO:0000781,GO:0000785,GO:0000792,GO:0001067,GO:0001069,GO:0001654,GO:0001745,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0003727,GO:0003729,GO:0003730,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005694,GO:0005700,GO:0005703,GO:0005737,GO:0006139,GO:0006259,GO:0006355,GO:0006357,GO:0006396,GO:0006397,GO:0006403,GO:0006405,GO:0006406,GO:0006417,GO:0006611,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006950,GO:0006996,GO:0007044,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007399,GO:0007417,GO:0007423,GO:0007548,GO:0008104,GO:0008150,GO:0008152,GO:0008380,GO:0008406,GO:0008584,GO:0008585,GO:0009266,GO:0009408,GO:0009605,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009887,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010001,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010638,GO:0014070,GO:0015030,GO:0015031,GO:0015833,GO:0015931,GO:0016043,GO:0016070,GO:0016071,GO:0016233,GO:0016363,GO:0016441,GO:0016458,GO:0016604,GO:0016607,GO:0019219,GO:0019221,GO:0019222,GO:0019827,GO:0019899,GO:0019953,GO:0022008,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030154,GO:0030323,GO:0030324,GO:0030718,GO:0031047,GO:0031050,GO:0031053,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031503,GO:0031581,GO:0031667,GO:0031960,GO:0031974,GO:0031981,GO:0031982,GO:0032200,GO:0032204,GO:0032206,GO:0032268,GO:0032270,GO:0032392,GO:0032501,GO:0032502,GO:0032504,GO:0032838,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033119,GO:0033993,GO:0034097,GO:0034248,GO:0034250,GO:0034329,GO:0034330,GO:0034399,GO:0034470,GO:0034613,GO:0034641,GO:0034660,GO:0035062,GO:0035194,GO:0035195,GO:0035196,GO:0035198,GO:0035295,GO:0035722,GO:0035770,GO:0036002,GO:0036099,GO:0036464,GO:0036477,GO:0040029,GO:0042063,GO:0042162,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042886,GO:0042995,GO:0043005,GO:0043025,GO:0043047,GO:0043085,GO:0043170,GO:0043204,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043230,GO:0043231,GO:0043232,GO:0043233,GO:0043331,GO:0043484,GO:0043565,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044297,GO:0044421,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044463,GO:0044464,GO:0044703,GO:0044806,GO:0045137,GO:0045184,GO:0045727,GO:0045892,GO:0045934,GO:0045935,GO:0046483,GO:0046545,GO:0046546,GO:0046660,GO:0046661,GO:0046907,GO:0048024,GO:0048025,GO:0048027,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048592,GO:0048608,GO:0048609,GO:0048709,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050657,GO:0050658,GO:0050684,GO:0050686,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051028,GO:0051052,GO:0051054,GO:0051128,GO:0051130,GO:0051168,GO:0051169,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051236,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051276,GO:0051338,GO:0051347,GO:0051385,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0051972,GO:0051973,GO:0060249,GO:0060255,GO:0060541,GO:0061458,GO:0061980,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070062,GO:0070182,GO:0070671,GO:0070727,GO:0070887,GO:0070918,GO:0071013,GO:0071103,GO:0071166,GO:0071310,GO:0071345,GO:0071349,GO:0071359,GO:0071407,GO:0071426,GO:0071427,GO:0071598,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0080090,GO:0090304,GO:0090596,GO:0097157,GO:0097159,GO:0097458,GO:0098505,GO:0098687,GO:0098727,GO:0098847,GO:0099568,GO:0120025,GO:0120038,GO:0120111,GO:1901360,GO:1901363,GO:1901698,GO:1901699,GO:1902494,GO:1902679,GO:1903311,GO:1903312,GO:1903506,GO:1903507,GO:1903561,GO:1904356,GO:1904358,GO:1905661,GO:1905663,GO:1990247,GO:1990428,GO:1990715,GO:1990904,GO:2000112,GO:2000113,GO:2000278,GO:2000573,GO:2001141,GO:2001252	-	ko:K12741,ko:K13158,ko:K14411	ko03015,ko03040,map03015,map03040	-	-	-	ko00000,ko00001,ko03019,ko03041,ko04147	-	-	-	RRM_1
k59_677612_1	713586.KB900536_gene1214	7.12e-91	278.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1WWJU@135613|Chromatiales	135613|Chromatiales	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_285834_1	335543.Sfum_3133	3.4e-88	288.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQVU@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_755830_1	717785.HYPMC_2110	8.97e-90	270.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2TQQ5@28211|Alphaproteobacteria,3N664@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_560031_1	530564.Psta_3267	2.99e-66	228.0	COG2373@1|root,COG2373@2|Bacteria,2IWRT@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
k59_364623_1	631454.N177_4163	3.4e-239	676.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,1JNHF@119043|Rhodobiaceae	28211|Alphaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_521288_1	933262.AXAM01000002_gene530	8.59e-48	154.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,42TVD@68525|delta/epsilon subdivisions,2WQPX@28221|Deltaproteobacteria,2MKA9@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Belongs to the bacterial histone-like protein family	ihfB	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_521288_2	933262.AXAM01000002_gene531	5.42e-14	68.9	COG0250@1|root,COG0250@2|Bacteria,1QTE5@1224|Proteobacteria,42QT0@68525|delta/epsilon subdivisions,2WN4B@28221|Deltaproteobacteria,2MJNB@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Transcription termination factor nusG	-	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
k59_873348_2	686340.Metal_1942	5.45e-59	187.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,1S263@1236|Gammaproteobacteria,1XEZ3@135618|Methylococcales	135618|Methylococcales	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_1187228_1	1286106.MPL1_09722	4.27e-14	72.4	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,45ZXN@72273|Thiotrichales	72273|Thiotrichales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_1187228_2	945550.VISI1226_20405	6.09e-29	108.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1XWV4@135623|Vibrionales	135623|Vibrionales	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_717421_1	1515746.HR45_00370	6.72e-42	158.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,2Q9IC@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM peptidase M16 domain protein	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_755844_1	1205680.CAKO01000038_gene1670	2.47e-80	256.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2JPPV@204441|Rhodospirillales	204441|Rhodospirillales	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_1108773_1	177437.HRM2_35300	4.45e-31	127.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,42KZP@68525|delta/epsilon subdivisions,2WKSV@28221|Deltaproteobacteria,2MHUQ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,PAS
k59_1147755_1	1026970.XP_008849559.1	2.29e-166	478.0	KOG2479@1|root,KOG2479@2759|Eukaryota,38G4P@33154|Opisthokonta,3BBTN@33208|Metazoa,3CTS3@33213|Bilateria,47ZVB@7711|Chordata,492ZT@7742|Vertebrata,3JBNZ@40674|Mammalia,35KCZ@314146|Euarchontoglires,4Q31M@9989|Rodentia	33208|Metazoa	J	cap-dependent translational initiation	EIF3D	GO:0000339,GO:0001732,GO:0002181,GO:0002183,GO:0002191,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005852,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016032,GO:0016043,GO:0019080,GO:0019081,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051704,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071541,GO:0071704,GO:0071826,GO:0071840,GO:0075522,GO:0075525,GO:0080090,GO:0097159,GO:0098808,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902415,GO:1902416,GO:1905214,GO:1905216,GO:2000112	-	ko:K03251	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	eIF-3_zeta
k59_794888_1	9606.ENSP00000320866	1.48e-217	610.0	KOG0674@1|root,KOG0674@2759|Eukaryota,38DI3@33154|Opisthokonta,3BFR1@33208|Metazoa,3CX8Y@33213|Bilateria,4816A@7711|Chordata,496ME@7742|Vertebrata,3J6M2@40674|Mammalia,359R1@314146|Euarchontoglires,4MB16@9443|Primates,4N5KC@9604|Hominidae	33208|Metazoa	O	Calreticulin family	CALR	GO:0000003,GO:0000122,GO:0001669,GO:0001846,GO:0001848,GO:0001849,GO:0002376,GO:0002396,GO:0002397,GO:0002474,GO:0002478,GO:0002479,GO:0002501,GO:0002502,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003008,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005102,GO:0005178,GO:0005488,GO:0005506,GO:0005509,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005783,GO:0005788,GO:0005789,GO:0005790,GO:0005793,GO:0005794,GO:0005829,GO:0005844,GO:0005886,GO:0006355,GO:0006357,GO:0006417,GO:0006457,GO:0006611,GO:0006807,GO:0006810,GO:0006873,GO:0006874,GO:0006875,GO:0006886,GO:0006897,GO:0006898,GO:0006906,GO:0006913,GO:0006950,GO:0006984,GO:0006986,GO:0006996,GO:0007010,GO:0007044,GO:0007154,GO:0007165,GO:0007275,GO:0007276,GO:0007283,GO:0007399,GO:0007417,GO:0007422,GO:0007507,GO:0007568,GO:0007569,GO:0007588,GO:0007610,GO:0007635,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0008270,GO:0008284,GO:0009266,GO:0009408,GO:0009628,GO:0009636,GO:0009719,GO:0009725,GO:0009755,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009897,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010226,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010564,GO:0010594,GO:0010595,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010632,GO:0010634,GO:0010646,GO:0010647,GO:0010648,GO:0010720,GO:0010721,GO:0010769,GO:0010770,GO:0010810,GO:0010811,GO:0010941,GO:0010948,GO:0012501,GO:0012505,GO:0012506,GO:0014070,GO:0014706,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016050,GO:0016192,GO:0016528,GO:0016529,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019725,GO:0019882,GO:0019884,GO:0019899,GO:0019953,GO:0022008,GO:0022414,GO:0022417,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030003,GO:0030029,GO:0030036,GO:0030100,GO:0030139,GO:0030141,GO:0030154,GO:0030155,GO:0030176,GO:0030246,GO:0030334,GO:0030335,GO:0030336,GO:0030421,GO:0030431,GO:0030496,GO:0030518,GO:0030522,GO:0030659,GO:0030666,GO:0030670,GO:0030865,GO:0030866,GO:0030968,GO:0031012,GO:0031090,GO:0031224,GO:0031227,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031410,GO:0031581,GO:0031625,GO:0031647,GO:0031958,GO:0031967,GO:0031974,GO:0031975,GO:0031982,GO:0031983,GO:0031984,GO:0032101,GO:0032103,GO:0032268,GO:0032269,GO:0032355,GO:0032501,GO:0032502,GO:0032504,GO:0032870,GO:0032879,GO:0032991,GO:0033036,GO:0033043,GO:0033116,GO:0033143,GO:0033144,GO:0033218,GO:0033365,GO:0033554,GO:0033574,GO:0033993,GO:0034248,GO:0034249,GO:0034329,GO:0034330,GO:0034504,GO:0034613,GO:0034620,GO:0034622,GO:0034975,GO:0034976,GO:0035051,GO:0035257,GO:0035258,GO:0035966,GO:0035967,GO:0036500,GO:0040012,GO:0040013,GO:0040017,GO:0040020,GO:0042048,GO:0042127,GO:0042175,GO:0042221,GO:0042277,GO:0042493,GO:0042562,GO:0042590,GO:0042592,GO:0042692,GO:0042824,GO:0042886,GO:0042921,GO:0042981,GO:0043067,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043401,GO:0043900,GO:0043901,GO:0043933,GO:0044085,GO:0044183,GO:0044238,GO:0044322,GO:0044389,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0044877,GO:0045169,GO:0045184,GO:0045335,GO:0045471,GO:0045595,GO:0045596,GO:0045597,GO:0045664,GO:0045665,GO:0045785,GO:0045786,GO:0045787,GO:0045807,GO:0045892,GO:0045934,GO:0046677,GO:0046872,GO:0046907,GO:0046914,GO:0048002,GO:0048232,GO:0048284,GO:0048385,GO:0048387,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0048609,GO:0048699,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0048878,GO:0050681,GO:0050764,GO:0050766,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050821,GO:0050839,GO:0050896,GO:0050920,GO:0050921,GO:0051049,GO:0051050,GO:0051082,GO:0051087,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051146,GO:0051168,GO:0051169,GO:0051171,GO:0051172,GO:0051179,GO:0051208,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051270,GO:0051271,GO:0051272,GO:0051427,GO:0051445,GO:0051604,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051960,GO:0051961,GO:0055007,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0060205,GO:0060255,GO:0060284,GO:0060537,GO:0060627,GO:0061024,GO:0061025,GO:0061061,GO:0061077,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0070887,GO:0071156,GO:0071157,GO:0071241,GO:0071248,GO:0071285,GO:0071310,GO:0071383,GO:0071396,GO:0071407,GO:0071495,GO:0071556,GO:0071682,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0072359,GO:0072503,GO:0072507,GO:0080090,GO:0090174,GO:0090398,GO:0097159,GO:0097223,GO:0097305,GO:0097708,GO:0098552,GO:0098553,GO:0098588,GO:0098657,GO:0098771,GO:0098796,GO:0098805,GO:0098827,GO:0099503,GO:1900024,GO:1900026,GO:1901163,GO:1901164,GO:1901222,GO:1901224,GO:1901363,GO:1901564,GO:1901654,GO:1901700,GO:1902531,GO:1902533,GO:1902679,GO:1903506,GO:1903507,GO:1990668,GO:1990904,GO:2000026,GO:2000112,GO:2000113,GO:2000145,GO:2000146,GO:2000147,GO:2000241,GO:2000242,GO:2000508,GO:2000510,GO:2001141	-	ko:K08057	ko04141,ko04145,ko04612,ko05142,ko05166,map04141,map04145,map04612,map05142,map05166	-	-	-	ko00000,ko00001,ko03110,ko04091	-	-	-	Calreticulin
k59_1147757_1	1122135.KB893137_gene1264	2.44e-77	238.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,2TUHN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type tungstate transport system, periplasmic component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
k59_1069253_1	317655.Sala_0368	2.71e-38	140.0	COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,2TSYY@28211|Alphaproteobacteria,2K1NF@204457|Sphingomonadales	204457|Sphingomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_1069253_2	501479.ACNW01000113_gene4027	0.000459	43.1	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits	MA20_06130	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
k59_1032143_1	768066.HELO_4289	1.89e-21	96.7	COG2267@1|root,COG2267@2|Bacteria,1RAQZ@1224|Proteobacteria,1S2YX@1236|Gammaproteobacteria,1XJ98@135619|Oceanospirillales	135619|Oceanospirillales	I	COG2267 Lysophospholipase	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
k59_324926_1	1121923.GPUN_0387	3.2e-86	267.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,46A4Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
k59_90728_2	1121439.dsat_0638	2.72e-99	295.0	COG0437@1|root,COG0437@2|Bacteria,1RCHX@1224|Proteobacteria,42S80@68525|delta/epsilon subdivisions,2X5D4@28221|Deltaproteobacteria,2MEPC@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
k59_873403_1	1268237.G114_07174	2.87e-49	165.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1Y3H9@135624|Aeromonadales	135624|Aeromonadales	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_1112190_1	1379281.AVAG01000017_gene1000	1.21e-62	216.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MG2T@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_210995_1	566466.NOR53_420	0.000842	45.8	2EM9G@1|root,33EYK@2|Bacteria,1P8EM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_915638_1	517418.Ctha_0617	3.12e-44	163.0	COG1138@1|root,COG1138@2|Bacteria,1FEUA@1090|Chlorobi	1090|Chlorobi	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_1232335_1	9606.ENSP00000259457	1.44e-175	490.0	COG0638@1|root,KOG0173@2759|Eukaryota,38CTY@33154|Opisthokonta,3BEBY@33208|Metazoa,3CUEU@33213|Bilateria,47Z2B@7711|Chordata,490US@7742|Vertebrata,3J5M6@40674|Mammalia,35AJ4@314146|Euarchontoglires,4MDIX@9443|Primates,4N44H@9604|Hominidae	33208|Metazoa	O	Proteasome beta subunits C terminal	PSMB7	GO:0000502,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005839,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0006959,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0012505,GO:0016192,GO:0016579,GO:0016787,GO:0019538,GO:0019774,GO:0019941,GO:0030141,GO:0030163,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032940,GO:0032991,GO:0034774,GO:0036211,GO:0036230,GO:0042119,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0051603,GO:0060205,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0097708,GO:0099503,GO:0101002,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904813,GO:1905368,GO:1905369,GO:1990111	3.4.25.1	ko:K02733,ko:K02739	ko03050,map03050	M00337,M00340	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Pr_beta_C,Proteasome
k59_171700_1	743720.Psefu_3515	2.07e-87	282.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,1YWIN@136845|Pseudomonas putida group	1236|Gammaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iECs_1301.ECs5024,iG2583_1286.G2583_4866	Acyltransferase
k59_1151214_1	443144.GM21_0993	3.87e-50	169.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42S4S@68525|delta/epsilon subdivisions,2WNIV@28221|Deltaproteobacteria,43S1H@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	cytidylate kinase activity	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k59_1036824_1	1304885.AUEY01000052_gene1554	2.68e-39	149.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria,2MJCC@213118|Desulfobacterales	28221|Deltaproteobacteria	NTU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,T2SSE,T2SSE_N
k59_1036825_2	323850.Shew_0927	1.31e-235	662.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,2Q9PB@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_53860_1	335543.Sfum_2961	5.19e-84	263.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria,2MQBT@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_1151239_1	572477.Alvin_0126	9.96e-79	246.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,1WX5B@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_408989_1	1267535.KB906767_gene271	1.95e-14	76.3	2E1AY@1|root,32WQW@2|Bacteria,3Y8WG@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1232405_1	52644.XP_010565012.1	4.12e-119	342.0	KOG3320@1|root,KOG3320@2759|Eukaryota,39ERP@33154|Opisthokonta,3B9CB@33208|Metazoa,3CWTF@33213|Bilateria,484W9@7711|Chordata,48YQV@7742|Vertebrata,4GU24@8782|Aves	33208|Metazoa	J	ribosomal protein S7	RPS7	GO:0000184,GO:0000956,GO:0001838,GO:0001841,GO:0001843,GO:0002009,GO:0002181,GO:0002376,GO:0002520,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003729,GO:0003730,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007275,GO:0007399,GO:0008104,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0014020,GO:0015031,GO:0015833,GO:0015935,GO:0016070,GO:0016071,GO:0016072,GO:0016331,GO:0019222,GO:0019439,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021915,GO:0022613,GO:0022626,GO:0022627,GO:0023051,GO:0023056,GO:0030097,GO:0030154,GO:0030162,GO:0030234,GO:0030684,GO:0030686,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031647,GO:0031974,GO:0031981,GO:0032040,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034470,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0035148,GO:0035239,GO:0035295,GO:0042176,GO:0042177,GO:0042254,GO:0042274,GO:0042886,GO:0042981,GO:0043009,GO:0043043,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0045861,GO:0046483,GO:0046700,GO:0046907,GO:0048027,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048598,GO:0048646,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0051438,GO:0051444,GO:0051641,GO:0051649,GO:0051726,GO:0055105,GO:0055106,GO:0060255,GO:0060429,GO:0060562,GO:0060606,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072175,GO:0072594,GO:0072599,GO:0072657,GO:0080090,GO:0090150,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901796,GO:1901798,GO:1902253,GO:1902255,GO:1902531,GO:1902533,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1904666,GO:1904667,GO:1990904,GO:1990948,GO:2000058,GO:2000059,GO:2001233,GO:2001235,GO:2001242,GO:2001244	-	ko:K02993	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7e
k59_289702_2	1318628.MARLIPOL_02065	1.8e-05	47.0	2ETDD@1|root,33KX6@2|Bacteria,1NHJB@1224|Proteobacteria,1SIBS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_409016_1	1167006.UWK_00622	4.54e-19	81.6	COG2204@1|root,COG2204@2|Bacteria,1RHQV@1224|Proteobacteria,42T2A@68525|delta/epsilon subdivisions,2WPA0@28221|Deltaproteobacteria,2MKC4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_681231_1	153721.MYP_3871	1.25e-14	77.0	COG4313@1|root,COG4313@2|Bacteria,4NW4N@976|Bacteroidetes,47WR2@768503|Cytophagia	976|Bacteroidetes	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
k59_681231_2	583355.Caka_2179	1.07e-10	61.6	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
k59_1072628_1	1282356.H045_13775	8.54e-12	65.5	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,1SYCI@1236|Gammaproteobacteria,1YMND@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	F	Guanine deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_1072628_2	748247.AZKH_3354	3.54e-45	153.0	COG3194@1|root,COG3194@2|Bacteria,1RH5G@1224|Proteobacteria,2VT31@28216|Betaproteobacteria,2KWU3@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source	allA	-	4.3.2.3	ko:K01483	ko00230,ko01100,map00230,map01100	-	R00776	RC00153,RC00379	ko00000,ko00001,ko01000	-	-	-	Ureidogly_lyase
k59_798173_1	926692.AZYG01000079_gene405	9.77e-60	201.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,3WB6M@53433|Halanaerobiales	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_409039_1	1417296.U879_12725	2.83e-19	89.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2TTXT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_759368_1	9606.ENSP00000221978	4.35e-55	174.0	2BYS3@1|root,2SUH4@2759|Eukaryota,3AKFY@33154|Opisthokonta,3BZVJ@33208|Metazoa,3D6RY@33213|Bilateria,48E2U@7711|Chordata,49BVC@7742|Vertebrata,3JGFM@40674|Mammalia,35PQY@314146|Euarchontoglires,4MJ43@9443|Primates,4N156@9604|Hominidae	33208|Metazoa	S	Natural killer cell granule protein 7	NKG7	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	PMP22_Claudin
k59_250506_1	441620.Mpop_0102	2.08e-49	172.0	COG5433@1|root,COG5433@2|Bacteria,1MY25@1224|Proteobacteria,2U0Y8@28211|Alphaproteobacteria,1JXMI@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_524920_1	1379281.AVAG01000009_gene630	1.51e-49	166.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,42MZU@68525|delta/epsilon subdivisions,2WKKU@28221|Deltaproteobacteria,2M7X4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
k59_524920_2	555779.Dthio_PD1009	5.09e-75	240.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,42M60@68525|delta/epsilon subdivisions,2WITJ@28221|Deltaproteobacteria,2M9R3@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	dsrK	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_997575_1	391593.RCCS2_01713	4.62e-13	73.9	COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,2TVYD@28211|Alphaproteobacteria,2P1S0@2433|Roseobacter	28211|Alphaproteobacteria	T	COG4564 Signal transduction histidine kinase	degS	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,sCache_2
k59_524954_1	1123399.AQVE01000008_gene1486	5.58e-19	86.7	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1RNV5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta	liuB	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
k59_524954_2	1177928.TH2_00795	2.87e-43	151.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2JQYB@204441|Rhodospirillales	204441|Rhodospirillales	I	Belongs to the thiolase family	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_524993_1	1002367.HMPREF0673_01562	0.000141	45.4	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,2FMQC@200643|Bacteroidia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_1037051_1	1123368.AUIS01000005_gene305	2.16e-58	204.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,2NCFC@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Conserved region in glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_877174_1	177437.HRM2_26890	5.82e-30	117.0	COG0189@1|root,COG0189@2|Bacteria,1MWQA@1224|Proteobacteria,43B1R@68525|delta/epsilon subdivisions,2X6FW@28221|Deltaproteobacteria,2MJ6I@213118|Desulfobacterales	28221|Deltaproteobacteria	HJ	RimK-like ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_171923_1	335543.Sfum_1393	2.43e-75	233.0	COG0483@1|root,COG0483@2|Bacteria,1NVDS@1224|Proteobacteria,42ZN3@68525|delta/epsilon subdivisions,2WUWR@28221|Deltaproteobacteria,2MRNA@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_915862_1	748247.AZKH_0320	7.68e-47	165.0	COG3292@1|root,COG3292@2|Bacteria,1QU1S@1224|Proteobacteria,2VPDV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
k59_446268_1	335543.Sfum_1804	7.73e-93	298.0	COG1053@1|root,COG1148@1|root,COG1053@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_446268_2	335543.Sfum_1805	2.67e-28	110.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,42P51@68525|delta/epsilon subdivisions,2WK1J@28221|Deltaproteobacteria,2MR5M@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
k59_15147_1	96561.Dole_3238	1.56e-23	100.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2MMIV@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_15147_2	933262.AXAM01000003_gene2794	2.13e-23	97.1	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,2MI91@213118|Desulfobacterales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
k59_250652_1	1121405.dsmv_3083	1.24e-91	280.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2MI8E@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Protein of unknown function (DUF933)	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_739760_1	9606.ENSP00000293379	5.1e-180	530.0	KOG3637@1|root,KOG3637@2759|Eukaryota,38CFX@33154|Opisthokonta,3B96W@33208|Metazoa,3CUDX@33213|Bilateria,486UU@7711|Chordata,495EQ@7742|Vertebrata,3JB22@40674|Mammalia,35GU8@314146|Euarchontoglires,4MASQ@9443|Primates,4N01M@9604|Hominidae	33208|Metazoa	W	Integrin alpha	ITGA5	GO:0000003,GO:0000165,GO:0000902,GO:0000904,GO:0001525,GO:0001568,GO:0001655,GO:0001667,GO:0001704,GO:0001706,GO:0001707,GO:0001708,GO:0001726,GO:0001775,GO:0001822,GO:0001894,GO:0001932,GO:0001934,GO:0001944,GO:0001968,GO:0002009,GO:0002011,GO:0002020,GO:0002064,GO:0002065,GO:0002066,GO:0002119,GO:0002164,GO:0002165,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002474,GO:0002478,GO:0002479,GO:0002520,GO:0003006,GO:0003008,GO:0003674,GO:0004888,GO:0005102,GO:0005126,GO:0005154,GO:0005161,GO:0005172,GO:0005178,GO:0005215,GO:0005216,GO:0005244,GO:0005245,GO:0005261,GO:0005262,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005794,GO:0005829,GO:0005886,GO:0005887,GO:0005902,GO:0005912,GO:0005924,GO:0005925,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006887,GO:0006897,GO:0006909,GO:0006915,GO:0006928,GO:0006935,GO:0006950,GO:0006955,GO:0006996,GO:0007010,GO:0007044,GO:0007154,GO:0007155,GO:0007157,GO:0007159,GO:0007160,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007229,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007369,GO:0007399,GO:0007409,GO:0007411,GO:0007414,GO:0007417,GO:0007419,GO:0007424,GO:0007426,GO:0007427,GO:0007431,GO:0007435,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007492,GO:0007494,GO:0007498,GO:0007517,GO:0007552,GO:0007560,GO:0007600,GO:0007606,GO:0007608,GO:0007610,GO:0007611,GO:0007613,GO:0008037,GO:0008038,GO:0008104,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008305,GO:0008324,GO:0008587,GO:0009605,GO:0009611,GO:0009653,GO:0009790,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009897,GO:0009925,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010556,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010631,GO:0010646,GO:0010647,GO:0010648,GO:0010669,GO:0010743,GO:0010745,GO:0010810,GO:0010811,GO:0010869,GO:0010871,GO:0010883,GO:0010888,GO:0010927,GO:0010941,GO:0012501,GO:0012505,GO:0012506,GO:0015026,GO:0015075,GO:0015085,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016032,GO:0016043,GO:0016192,GO:0016203,GO:0016310,GO:0016323,GO:0016477,GO:0019058,GO:0019220,GO:0019222,GO:0019538,GO:0019838,GO:0019882,GO:0019884,GO:0019899,GO:0019953,GO:0019955,GO:0021551,GO:0022008,GO:0022412,GO:0022414,GO:0022603,GO:0022607,GO:0022610,GO:0022612,GO:0022803,GO:0022832,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030001,GO:0030016,GO:0030017,GO:0030027,GO:0030029,GO:0030030,GO:0030036,GO:0030054,GO:0030055,GO:0030097,GO:0030100,GO:0030139,GO:0030141,GO:0030154,GO:0030155,GO:0030175,GO:0030182,GO:0030198,GO:0030239,GO:0030260,GO:0030334,GO:0030335,GO:0030659,GO:0030667,GO:0030707,GO:0030855,GO:0030947,GO:0030949,GO:0031032,GO:0031090,GO:0031175,GO:0031224,GO:0031226,GO:0031252,GO:0031253,GO:0031256,GO:0031258,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031401,GO:0031410,GO:0031430,GO:0031527,GO:0031528,GO:0031589,GO:0031672,GO:0031982,GO:0032231,GO:0032268,GO:0032270,GO:0032368,GO:0032369,GO:0032501,GO:0032502,GO:0032504,GO:0032587,GO:0032879,GO:0032940,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033627,GO:0033631,GO:0034113,GO:0034220,GO:0034329,GO:0034330,GO:0034446,GO:0034678,GO:0034683,GO:0034684,GO:0034686,GO:0035099,GO:0035107,GO:0035114,GO:0035120,GO:0035152,GO:0035160,GO:0035162,GO:0035220,GO:0035239,GO:0035272,GO:0035295,GO:0035313,GO:0035556,GO:0035579,GO:0035821,GO:0035866,GO:0035867,GO:0035868,GO:0035987,GO:0036211,GO:0036230,GO:0038023,GO:0038027,GO:0038034,GO:0040011,GO:0040012,GO:0040017,GO:0040025,GO:0040028,GO:0042058,GO:0042059,GO:0042060,GO:0042119,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042330,GO:0042383,GO:0042581,GO:0042590,GO:0042592,GO:0042692,GO:0042981,GO:0042995,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043184,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043235,GO:0043277,GO:0043292,GO:0043299,GO:0043312,GO:0043412,GO:0043900,GO:0043901,GO:0043903,GO:0044003,GO:0044068,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044319,GO:0044403,GO:0044409,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044449,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044877,GO:0045055,GO:0045165,GO:0045178,GO:0045185,GO:0045202,GO:0045214,GO:0045321,GO:0045335,GO:0045595,GO:0045596,GO:0045714,GO:0045715,GO:0045765,GO:0045766,GO:0045785,GO:0045807,GO:0045937,GO:0046718,GO:0046873,GO:0046903,GO:0046982,GO:0046983,GO:0048002,GO:0048010,GO:0048332,GO:0048333,GO:0048468,GO:0048477,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048563,GO:0048565,GO:0048568,GO:0048569,GO:0048580,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0048871,GO:0050431,GO:0050730,GO:0050731,GO:0050746,GO:0050748,GO:0050764,GO:0050766,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050877,GO:0050890,GO:0050896,GO:0050900,GO:0050919,GO:0051049,GO:0051050,GO:0051051,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051272,GO:0051492,GO:0051493,GO:0051674,GO:0051701,GO:0051704,GO:0051716,GO:0051806,GO:0051817,GO:0051828,GO:0052066,GO:0052190,GO:0052191,GO:0052231,GO:0052370,GO:0052522,GO:0055001,GO:0055002,GO:0055085,GO:0055120,GO:0055123,GO:0060089,GO:0060099,GO:0060100,GO:0060249,GO:0060255,GO:0060429,GO:0060538,GO:0060541,GO:0060548,GO:0060562,GO:0060627,GO:0061061,GO:0061062,GO:0061564,GO:0065007,GO:0065008,GO:0070161,GO:0070371,GO:0070588,GO:0070838,GO:0070851,GO:0070925,GO:0071062,GO:0071704,GO:0071840,GO:0071944,GO:0072001,GO:0072325,GO:0072327,GO:0072358,GO:0072359,GO:0072511,GO:0080090,GO:0090130,GO:0090132,GO:0090287,GO:0090504,GO:0090505,GO:0097190,GO:0097191,GO:0097192,GO:0097435,GO:0097485,GO:0097708,GO:0098552,GO:0098588,GO:0098590,GO:0098609,GO:0098636,GO:0098655,GO:0098657,GO:0098660,GO:0098662,GO:0098742,GO:0098796,GO:0098797,GO:0098802,GO:0098805,GO:0098858,GO:0099080,GO:0099081,GO:0099503,GO:0099512,GO:0110020,GO:0110053,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:1901074,GO:1901076,GO:1901184,GO:1901185,GO:1901342,GO:1901564,GO:1902903,GO:1903670,GO:1903672,GO:1904018,GO:1905153,GO:1905155,GO:1905952,GO:1905953,GO:1990430,GO:2000026,GO:2000145,GO:2000147,GO:2000209,GO:2000425,GO:2000427,GO:2000535,GO:2000536,GO:2000811,GO:2001233,GO:2001234,GO:2001236,GO:2001237	-	ko:K06484,ko:K06487,ko:K06584	ko04145,ko04151,ko04510,ko04512,ko04514,ko04640,ko04810,ko04919,ko05100,ko05131,ko05133,ko05165,ko05200,ko05205,ko05206,ko05222,ko05410,ko05412,ko05414,ko05418,map04145,map04151,map04510,map04512,map04514,map04640,map04810,map04919,map05100,map05131,map05133,map05165,map05200,map05205,map05206,map05222,map05410,map05412,map05414,map05418	-	-	-	ko00000,ko00001,ko04090,ko04131,ko04147,ko04516	-	-	-	FG-GAP,Integrin_alpha,Integrin_alpha2
k59_1091678_1	335543.Sfum_1831	2.37e-72	234.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,2MQWY@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_934751_1	1122194.AUHU01000004_gene1489	1.95e-43	153.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,466CP@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_190443_1	347834.RHE_CH00782	1.28e-126	370.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,4BA4C@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_389095_1	713586.KB900536_gene1167	7.28e-06	47.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1WWAW@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_389095_2	765913.ThidrDRAFT_1739	2.43e-26	100.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,1WYZN@135613|Chromatiales	135613|Chromatiales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_389095_3	717774.Marme_0239	9.52e-14	68.9	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1XH61@135619|Oceanospirillales	135619|Oceanospirillales	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
k59_270705_1	1121033.AUCF01000013_gene1628	6.97e-18	85.1	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,2JS9K@204441|Rhodospirillales	204441|Rhodospirillales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_270705_2	1255043.TVNIR_1527	2.04e-25	95.1	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ2Z@135613|Chromatiales	135613|Chromatiales	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_309444_1	1207063.P24_08494	9.37e-46	159.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSUS@28211|Alphaproteobacteria,2JPGK@204441|Rhodospirillales	204441|Rhodospirillales	K	transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
k59_151433_1	335543.Sfum_3597	1.54e-106	322.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42N6E@68525|delta/epsilon subdivisions,2WJXG@28221|Deltaproteobacteria,2MQ6T@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_622994_1	379731.PST_1817	8.71e-61	205.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1Z2GV@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	V	COG0534 Na -driven multidrug efflux pump	pmpM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_192299_1	96561.Dole_2220	1.32e-82	255.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2MI9R@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_741885_1	1343739.PAP_03605	7.65e-19	85.5	COG0639@1|root,arCOG01143@2157|Archaea,2XUDG@28890|Euryarchaeota,2435N@183968|Thermococci	183968|Thermococci	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k59_467232_1	330214.NIDE2440	1.4e-37	145.0	COG0667@1|root,COG1331@1|root,COG0667@2|Bacteria,COG1331@2|Bacteria,3J0HX@40117|Nitrospirae	40117|Nitrospirae	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_311281_1	335543.Sfum_1962	3.46e-62	202.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42QUN@68525|delta/epsilon subdivisions,2WN6Q@28221|Deltaproteobacteria,2MRR2@213462|Syntrophobacterales	28221|Deltaproteobacteria	OU	TIGRFAM signal peptide peptidase SppA, 36K type	sppA2	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
k59_899056_2	1307759.JOMJ01000003_gene1714	5.71e-69	233.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_311289_1	378806.STAUR_0336	2.43e-26	108.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42R6X@68525|delta/epsilon subdivisions,2WMY9@28221|Deltaproteobacteria,2Z18Z@29|Myxococcales	28221|Deltaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_781131_1	1265313.HRUBRA_02746	4.35e-90	274.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	glucose sorbosone	yliI	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
k59_272521_1	1453501.JELR01000002_gene868	8.8e-109	340.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,465IE@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	ERAP1-like C-terminal domain	-	-	3.4.11.14	ko:K01263	-	-	-	-	ko00000,ko01000	-	-	-	ERAP1_C,Peptidase_M1
k59_272523_1	1336233.JAEH01000006_gene2401	1.05e-11	64.7	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1MU2H@1224|Proteobacteria,1SMV9@1236|Gammaproteobacteria,2Q94Z@267890|Shewanellaceae	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_20,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,Pyr_redox_2
k59_272523_2	485915.Dret_0414	9.47e-17	79.0	COG0247@1|root,COG0247@2|Bacteria,1N5Q2@1224|Proteobacteria,42P5D@68525|delta/epsilon subdivisions,2WJ9I@28221|Deltaproteobacteria,2M7XG@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8,Fer4_9
k59_272526_1	335543.Sfum_1725	8.53e-108	320.0	COG0067@1|root,COG0067@2|Bacteria,1MW6C@1224|Proteobacteria,42MTE@68525|delta/epsilon subdivisions,2WJ9E@28221|Deltaproteobacteria,2MR76@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1056547_1	1168067.JAGP01000001_gene1483	5.01e-20	96.7	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,1RQGJ@1236|Gammaproteobacteria,460CP@72273|Thiotrichales	72273|Thiotrichales	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
k59_1056551_1	1254432.SCE1572_20435	1.36e-49	167.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,42VTP@68525|delta/epsilon subdivisions,2WRQG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
k59_74778_1	665942.HMPREF1022_02132	1.07e-76	248.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WJXY@28221|Deltaproteobacteria,2M826@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_781168_1	375286.mma_1976	1.86e-80	249.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,472SB@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_467275_2	234267.Acid_3225	0.000858	45.1	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C
k59_390899_1	1158292.JPOE01000002_gene3542	1.31e-55	180.0	COG1853@1|root,COG1853@2|Bacteria,1PD48@1224|Proteobacteria,2W9SU@28216|Betaproteobacteria,1KP8Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
k59_625099_1	237368.SCABRO_04028	2.02e-67	219.0	COG0644@1|root,COG0664@1|root,COG0644@2|Bacteria,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	prnA	-	1.14.19.9	ko:K07058,ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_5,Trp_halogenase,cNMP_binding
k59_781177_1	105422.BBPM01000022_gene2940	3.26e-11	62.0	COG3012@1|root,COG3012@2|Bacteria,2IQEM@201174|Actinobacteria,2NJ45@228398|Streptacidiphilus	201174|Actinobacteria	S	Belongs to the UPF0225 family	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
k59_781177_2	631362.Thi970DRAFT_01083	4.03e-12	63.2	2DBZI@1|root,2ZC1J@2|Bacteria,1RC57@1224|Proteobacteria,1S2Q2@1236|Gammaproteobacteria,1WY10@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_311326_1	648757.Rvan_3213	5.8e-36	137.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,2TZ0I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_899132_1	644282.Deba_2271	3.14e-63	207.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
k59_702882_1	9606.ENSP00000262193	1.53e-155	437.0	COG0638@1|root,KOG0179@2759|Eukaryota,38EK6@33154|Opisthokonta,3BGIT@33208|Metazoa,3CV39@33213|Bilateria,488R3@7711|Chordata,497SJ@7742|Vertebrata,3JDK1@40674|Mammalia,35DCY@314146|Euarchontoglires,4M6NI@9443|Primates,4MUH7@9604|Hominidae	33208|Metazoa	O	Proteasome subunit	PSMB1	GO:0000502,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005839,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0012505,GO:0016192,GO:0016579,GO:0019538,GO:0019774,GO:0019941,GO:0030141,GO:0030163,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032940,GO:0032991,GO:0034774,GO:0036211,GO:0036230,GO:0042119,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0051603,GO:0060205,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0097708,GO:0099503,GO:0101002,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904813,GO:1905368,GO:1905369	3.4.25.1	ko:K02732	ko03050,map03050	M00337,M00340	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
k59_781237_1	1198232.CYCME_1256	1.08e-42	152.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,46066@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
k59_781237_2	1537994.JQFW01000056_gene850	0.00078	41.2	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,464A2@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_1133860_2	1340434.AXVA01000019_gene897	5.59e-29	109.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,1ZFRE@1386|Bacillus	91061|Bacilli	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
k59_272639_1	1049564.TevJSym_ar00340	6.4e-24	105.0	COG1729@1|root,COG1729@2|Bacteria,1MZ7N@1224|Proteobacteria,1T3FY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1133878_2	1038858.AXBA01000003_gene4188	7.6e-19	88.2	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2TS1C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	MA20_32350	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
k59_899189_1	713586.KB900536_gene1063	1.32e-25	108.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,1WX31@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_36338_1	9593.ENSGGOP00000020419	1.32e-121	362.0	COG0459@1|root,KOG0364@2759|Eukaryota,38GPW@33154|Opisthokonta,3BFX2@33208|Metazoa,3CYB8@33213|Bilateria,47ZAK@7711|Chordata,48XID@7742|Vertebrata,3JCEM@40674|Mammalia,35IMN@314146|Euarchontoglires,4MFBM@9443|Primates,4MZDD@9604|Hominidae	33208|Metazoa	O	unfolded protein binding	CCT3	GO:0000003,GO:0002199,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005832,GO:0005856,GO:0005874,GO:0005886,GO:0006457,GO:0006458,GO:0006810,GO:0007338,GO:0007339,GO:0008037,GO:0008150,GO:0009566,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009988,GO:0010556,GO:0010557,GO:0010604,GO:0010638,GO:0015630,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019953,GO:0022414,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031647,GO:0032204,GO:0032206,GO:0032210,GO:0032212,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033044,GO:0035036,GO:0042623,GO:0043209,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044183,GO:0044297,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044703,GO:0045935,GO:0046931,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050821,GO:0051052,GO:0051054,GO:0051082,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051704,GO:0060255,GO:0060341,GO:0061077,GO:0065003,GO:0065007,GO:0065008,GO:0070201,GO:0070202,GO:0070203,GO:0071840,GO:0071944,GO:0080090,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0101031,GO:1901998,GO:1903827,GO:1903829,GO:1904356,GO:1904358,GO:1904814,GO:1904816,GO:1904851,GO:1904951,GO:2000112,GO:2000278,GO:2000573,GO:2001252	-	ko:K09495	-	-	-	-	ko00000,ko03036,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_702949_1	194439.CT0867	1.05e-67	228.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1FEM4@1090|Chlorobi	1090|Chlorobi	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4_9,FlpD,Pyr_redox_2
k59_859231_1	234267.Acid_5940	1.3e-18	91.3	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
k59_311436_1	1487921.DP68_17100	8.1e-105	322.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,36DS1@31979|Clostridiaceae	186801|Clostridia	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_1173520_1	941449.dsx2_0363	1.72e-88	286.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2M9PX@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
k59_662664_1	1122135.KB893170_gene2791	7.78e-165	479.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TQJR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	prpE	GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017144,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046950,GO:0046951,GO:0070013,GO:0071704,GO:1901568,GO:1901570,GO:1901576,GO:1902224	6.2.1.1,6.2.1.17	ko:K01895,ko:K01908	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_311445_1	98439.AJLL01000051_gene3546	9.77e-31	121.0	COG0399@1|root,COG0399@2|Bacteria,1G0IM@1117|Cyanobacteria,1JHSZ@1189|Stigonemataceae	1117|Cyanobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_192464_1	1286631.X805_25210	1.7e-29	121.0	COG0210@1|root,COG0210@2|Bacteria,1MWW6@1224|Proteobacteria,2VM7D@28216|Betaproteobacteria,1KMZ5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,NERD,UvrD-helicase,UvrD_C,UvrD_C_2
k59_702991_1	247639.MGP2080_10978	1.47e-05	46.2	COG3203@1|root,COG3203@2|Bacteria,1P0QZ@1224|Proteobacteria,1SRNB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_350801_1	1121403.AUCV01000008_gene1610	7.97e-89	270.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,2MI1B@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM NAD dependent epimerase dehydratase family	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_36383_1	1274524.BSONL12_03414	7.35e-23	102.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZPZU@1386|Bacillus	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	yhfL	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_1212841_1	118797.XP_007470157.1	3.83e-154	444.0	KOG0115@1|root,KOG0115@2759|Eukaryota,38PBU@33154|Opisthokonta,3BEND@33208|Metazoa,3CTCF@33213|Bilateria,489CR@7711|Chordata,4906H@7742|Vertebrata,3JCC5@40674|Mammalia,4JB4H@91561|Cetartiodactyla	33208|Metazoa	A	non-POU domain-containing octamer-binding protein	NONO	GO:0000003,GO:0000375,GO:0000377,GO:0000398,GO:0000976,GO:0000977,GO:0000978,GO:0000980,GO:0000981,GO:0000987,GO:0001012,GO:0001067,GO:0001158,GO:0002218,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0003008,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0003723,GO:0003727,GO:0003729,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005667,GO:0005681,GO:0005730,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0007600,GO:0007601,GO:0007610,GO:0007617,GO:0007618,GO:0007619,GO:0007623,GO:0007632,GO:0008049,GO:0008150,GO:0008152,GO:0008187,GO:0008380,GO:0009314,GO:0009416,GO:0009453,GO:0009605,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010941,GO:0016070,GO:0016071,GO:0016363,GO:0016545,GO:0016604,GO:0016607,GO:0019098,GO:0019219,GO:0019222,GO:0019953,GO:0022414,GO:0023051,GO:0023057,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031347,GO:0031349,GO:0031974,GO:0031981,GO:0032501,GO:0032504,GO:0032991,GO:0034399,GO:0034641,GO:0035326,GO:0040011,GO:0042330,GO:0042331,GO:0042382,GO:0042752,GO:0042802,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043523,GO:0043524,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044703,GO:0044798,GO:0045088,GO:0045089,GO:0045433,GO:0045892,GO:0045934,GO:0046483,GO:0048065,GO:0048511,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048609,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050877,GO:0050896,GO:0050953,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051704,GO:0060179,GO:0060255,GO:0060548,GO:0065007,GO:0070013,GO:0070888,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090575,GO:0097159,GO:0140110,GO:1900407,GO:1900408,GO:1901214,GO:1901215,GO:1901360,GO:1901363,GO:1902175,GO:1902176,GO:1902531,GO:1902532,GO:1902679,GO:1902882,GO:1902883,GO:1903201,GO:1903202,GO:1903203,GO:1903204,GO:1903376,GO:1903377,GO:1903506,GO:1903507,GO:1990837,GO:1990904,GO:2000112,GO:2000113,GO:2001141,GO:2001233,GO:2001234,GO:2001242,GO:2001243	-	ko:K13214,ko:K13219	-	-	-	-	ko00000,ko01009,ko03021,ko03041	-	-	-	NOPS,RRM_1
k59_742104_1	933262.AXAM01000033_gene1642	2.77e-83	266.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MI52@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_391089_1	394.NGR_c08340	1.52e-76	243.0	COG3547@1|root,COG3547@2|Bacteria,1QYJU@1224|Proteobacteria,2U1TU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_818976_1	56780.SYN_02987	9.79e-97	295.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,42S30@68525|delta/epsilon subdivisions,2WQ5S@28221|Deltaproteobacteria,2MRTS@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_978494_2	1192034.CAP_5641	1.31e-06	53.1	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YWWP@29|Myxococcales	28221|Deltaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,Pkinase_Tyr,WD40
k59_703063_1	1517681.HW45_16855	2.23e-59	198.0	COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RMGW@1236|Gammaproteobacteria,1XUCK@135623|Vibrionales	135623|Vibrionales	F	COG2233 Xanthine uracil permeases	-	-	-	ko:K16345	-	-	-	-	ko00000,ko02000	2.A.40.4.2	-	-	Xan_ur_permease
k59_859334_1	1220589.CD32_16230	1.02e-12	64.7	COG2030@1|root,COG2030@2|Bacteria,1TUJW@1239|Firmicutes,4IFCZ@91061|Bacilli,3IYXQ@400634|Lysinibacillus	91061|Bacilli	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k59_859334_2	485913.Krac_9152	4.74e-20	86.7	COG2030@1|root,COG2030@2|Bacteria,2G91F@200795|Chloroflexi	200795|Chloroflexi	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
k59_703078_1	386456.JQKN01000001_gene2075	7.21e-76	242.0	COG0477@1|root,arCOG00143@2157|Archaea,2XUTR@28890|Euryarchaeota,23PFA@183925|Methanobacteria	183925|Methanobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_585778_1	1174504.AJTN02000035_gene3043	8.24e-44	156.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HC4S@91061|Bacilli,1ZQZX@1386|Bacillus	91061|Bacilli	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_978533_1	1122139.KB907862_gene752	4.38e-09	57.4	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,1XKCZ@135619|Oceanospirillales	135619|Oceanospirillales	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
k59_978533_2	565655.ECBG_00475	1.52e-08	57.4	COG1388@1|root,COG1705@1|root,COG3103@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,COG4991@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli,4AZE2@81852|Enterococcaceae	91061|Bacilli	MNU	defense response to other organism	-	-	-	ko:K02395,ko:K19223	-	-	-	-	ko00000,ko01000,ko01002,ko01011,ko02035	-	CBM50	-	Glucosaminidase,LysM,SH3_3,SH3_8,SLAP
k59_899324_1	1121405.dsmv_0666	1.4e-112	337.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2MI66@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_662779_1	335543.Sfum_2391	1.34e-85	270.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990,ko:K01992,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC2_membrane_3,ABC_tran
k59_75006_1	1121405.dsmv_0150	1.03e-39	139.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,2MIXA@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_978551_1	880072.Desac_2474	5.2e-101	307.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,2MQ63@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_1173688_1	1380394.JADL01000013_gene703	4.54e-44	155.0	COG0667@1|root,COG0667@2|Bacteria,1R5BH@1224|Proteobacteria,2TS0A@28211|Alphaproteobacteria,2JVHZ@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_350895_1	1307759.JOMJ01000003_gene1692	3.68e-63	207.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1PFBF@1224|Proteobacteria,42RAR@68525|delta/epsilon subdivisions,2WN52@28221|Deltaproteobacteria,2MAC7@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,SpoIIE
k59_1134070_1	1167006.UWK_03285	1.65e-104	309.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,43AKQ@68525|delta/epsilon subdivisions,2X60P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
k59_1212937_1	351746.Pput_5188	5.92e-90	279.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1YXF1@136845|Pseudomonas putida group	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.54,1.2.1.99	ko:K09472,ko:K12254	ko00330,ko01100,map00330,map01100	M00136	R02549,R03177,R07417,R07418	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_5278	Aldedh
k59_311614_1	1042377.AFPJ01000042_gene1018	1.82e-74	237.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,464BR@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Aminotransferase class-III	-	-	2.6.1.113	ko:K12256	ko00330,ko01100,map00330,map01100	-	R08714	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k59_937144_1	1205753.A989_15467	1.05e-10	62.4	COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,1SCYD@1236|Gammaproteobacteria,1X8J8@135614|Xanthomonadales	135614|Xanthomonadales	NU	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
k59_192605_1	420662.Mpe_A2344	2.02e-102	306.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2VHWA@28216|Betaproteobacteria,1KJEN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Sodium Bile acid symporter family	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
k59_585869_2	913325.N799_12455	4.47e-49	164.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,1RUSZ@1236|Gammaproteobacteria,1X5E2@135614|Xanthomonadales	135614|Xanthomonadales	E	N-formylglutamate amidohydrolase	hutG	-	3.5.1.68,3.5.3.8	ko:K01458,ko:K01479	ko00340,ko00630,ko01100,map00340,map00630,map01100	M00045	R00525,R02285	RC00165,RC00221,RC00323,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	FGase
k59_819083_1	443152.MDG893_13988	6.34e-10	59.3	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,4646B@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
k59_819083_2	59196.RICGR_0596	1.02e-26	98.2	COG1773@1|root,COG1773@2|Bacteria	2|Bacteria	C	rubredoxin	rubA	-	-	ko:K03618	-	-	-	-	ko00000	-	-	-	Rubredoxin
k59_376032_1	393595.ABO_0657	7.15e-34	129.0	COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1XHP4@135619|Oceanospirillales	135619|Oceanospirillales	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DUF3412,DUF4478,Lysine_decarbox
k59_376032_2	749222.Nitsa_1433	1.35e-33	121.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,42TV7@68525|delta/epsilon subdivisions,2YPWW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_1241710_1	9597.XP_003828141.1	4.8e-128	375.0	COG5184@1|root,KOG1426@2759|Eukaryota,39G0B@33154|Opisthokonta,3BDQC@33208|Metazoa,3CSPJ@33213|Bilateria,482TH@7711|Chordata,4923H@7742|Vertebrata,3J7S6@40674|Mammalia,35ATE@314146|Euarchontoglires,4MKNS@9443|Primates,4MS7H@9604|Hominidae	33208|Metazoa	DZ	Regulator of chromosome condensation	RCC1	GO:0000082,GO:0000226,GO:0000228,GO:0000278,GO:0000785,GO:0000790,GO:0000793,GO:0000794,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005085,GO:0005087,GO:0005088,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005694,GO:0005737,GO:0006606,GO:0006607,GO:0006810,GO:0006886,GO:0006913,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007059,GO:0007088,GO:0007275,GO:0007346,GO:0007399,GO:0007417,GO:0008104,GO:0008150,GO:0008536,GO:0009790,GO:0009792,GO:0009987,GO:0010564,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016032,GO:0016043,GO:0017016,GO:0017038,GO:0019899,GO:0022008,GO:0022402,GO:0022607,GO:0030154,GO:0031090,GO:0031267,GO:0031490,GO:0031491,GO:0031492,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032386,GO:0032501,GO:0032502,GO:0032879,GO:0032991,GO:0033036,GO:0033043,GO:0033365,GO:0034504,GO:0034613,GO:0042393,GO:0042886,GO:0043167,GO:0043168,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0044877,GO:0045184,GO:0045595,GO:0046822,GO:0046907,GO:0046982,GO:0046983,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050789,GO:0050793,GO:0050794,GO:0051020,GO:0051049,GO:0051128,GO:0051169,GO:0051170,GO:0051179,GO:0051225,GO:0051234,GO:0051239,GO:0051259,GO:0051262,GO:0051290,GO:0051291,GO:0051641,GO:0051649,GO:0051704,GO:0051726,GO:0051783,GO:0051960,GO:0060284,GO:0060341,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070727,GO:0070925,GO:0071702,GO:0071705,GO:0071840,GO:0072594,GO:0097159,GO:0098772,GO:1901363,GO:1901681,GO:1902850,GO:1903047,GO:2000026	-	ko:K11493	-	-	-	-	ko00000,ko03019,ko03036	-	-	-	RCC1,RCC1_2
k59_297940_1	574966.KB898646_gene3136	1.65e-30	109.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1XKH8@135619|Oceanospirillales	135619|Oceanospirillales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
k59_297940_2	1005048.CFU_2881	1.35e-15	74.7	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,47234@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	KR domain	fabG	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_258562_1	1125863.JAFN01000001_gene2311	2.36e-116	348.0	COG0215@1|root,COG0215@2|Bacteria	2|Bacteria	J	cysteine-tRNA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
k59_1159139_1	1121861.KB899942_gene3801	3.88e-15	72.8	COG3415@1|root,COG3415@2|Bacteria,1N7CS@1224|Proteobacteria,2UFAY@28211|Alphaproteobacteria,2JUR3@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,HTH_33
k59_923217_1	247633.GP2143_09832	5.17e-19	84.3	COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,1RRPK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2273 Beta-glucanase Beta-glucan synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_376057_1	420324.KI911955_gene3678	3.72e-34	132.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,1JU2Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	PFAM transcriptional regulator domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
k59_923226_1	391626.OAN307_c37570	4.2e-34	132.0	COG3547@1|root,COG3547@2|Bacteria,1QPKD@1224|Proteobacteria,2TUIG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_805500_1	95619.PM1_0226850	2.73e-40	142.0	COG0637@1|root,COG0637@2|Bacteria,1QTT8@1224|Proteobacteria,1T1GC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolase	-	-	3.1.3.5	ko:K20881	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
k59_805500_2	666681.M301_1378	3.03e-13	68.6	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,2VJWH@28216|Betaproteobacteria,2KMET@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Inositol monophosphatase family	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
k59_1198639_1	1265313.HRUBRA_00417	4.87e-68	222.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_258583_1	717785.HYPMC_1026	5.1e-54	181.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,3N67C@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_845769_1	880073.Calab_2598	3.3e-52	172.0	COG5340@1|root,COG5340@2|Bacteria,2NRRC@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1159173_1	443152.MDG893_06434	1.56e-84	262.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,464YF@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Transcriptional regulator	cysB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_1080149_1	247639.MGP2080_11348	2.5e-108	332.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_179787_2	391595.RLO149_c039590	1.02e-61	199.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,2P3M6@2433|Roseobacter	28211|Alphaproteobacteria	L	COG3547 Transposase and inactivated derivatives	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_534571_1	713587.THITH_07075	1.95e-123	367.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
k59_1080157_1	1411123.JQNH01000001_gene675	3.22e-83	258.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TT26@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_221128_1	1562701.BBOF01000034_gene1032	7.64e-33	123.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria,1K0W9@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
k59_221128_2	1085623.GNIT_3035	4.34e-18	81.6	COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,1RVJH@1236|Gammaproteobacteria,469D6@72275|Alteromonadaceae	1236|Gammaproteobacteria	PQ	Peptidase family S51	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
k59_179790_2	1535422.ND16A_3571	1.29e-88	271.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,2Q707@267889|Colwelliaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1080160_1	402881.Plav_2497	1.06e-85	266.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2TW27@28211|Alphaproteobacteria,1JNZY@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	2.7.10.2,3.3.2.9	ko:K01253,ko:K08253	ko00980,ko04976,ko05204,map00980,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
k59_728423_1	272134.KB731325_gene528	1.08e-32	130.0	COG0515@1|root,COG0642@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GGDEF,HATPase_c,HisKA,PAS_3,PAS_4,Pkinase,Response_reg,SpoIIE
k59_885152_1	85643.Tmz1t_3872	2.25e-37	145.0	COG1413@1|root,COG1729@1|root,COG4235@1|root,COG1413@2|Bacteria,COG1729@2|Bacteria,COG4235@2|Bacteria,1QVTH@1224|Proteobacteria,2VZGW@28216|Betaproteobacteria	1224|Proteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_19,TPR_8
k59_1120239_1	1175306.GWL_32430	8.92e-61	200.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,476PV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
k59_1198703_1	1117647.M5M_11490	1.24e-17	88.2	2BX7Z@1|root,2ZBYH@2|Bacteria,1RFFM@1224|Proteobacteria,1S5CF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	F plasmid transfer operon, TraF, protein	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
k59_767289_1	314278.NB231_10143	9.29e-57	199.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1WW84@135613|Chromatiales	135613|Chromatiales	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1007869_1	1379270.AUXF01000002_gene1387	3.8e-31	127.0	COG2091@1|root,COG2091@2|Bacteria,1ZUE3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_140116_1	765913.ThidrDRAFT_0640	1.79e-73	229.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1WXZW@135613|Chromatiales	135613|Chromatiales	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
k59_1120292_1	1082705.JIBP01000017_gene675	7.34e-43	155.0	COG0160@1|root,COG0160@2|Bacteria,1MX0Y@1224|Proteobacteria,1RQ9Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3
k59_1044338_1	550540.Fbal_2647	1.02e-22	89.7	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k59_1044338_2	1123229.AUBC01000006_gene875	2.77e-70	224.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,2TQMA@28211|Alphaproteobacteria,3JREF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome bd terminal oxidase subunit I	appC	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k59_258699_1	225937.HP15_2536	3.04e-50	177.0	COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,1RR9Q@1236|Gammaproteobacteria,465U3@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Pfam:DUF1446	atuA	-	-	-	-	-	-	-	-	-	-	-	AtuA
k59_963861_1	101510.RHA1_ro03757	1.49e-32	129.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4FX1G@85025|Nocardiaceae	201174|Actinobacteria	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_963865_1	670307.HYPDE_23078	9.64e-18	83.6	COG5055@1|root,COG5055@2|Bacteria,1QWK7@1224|Proteobacteria	1224|Proteobacteria	L	Protein of unknown function (DUF968)	-	-	-	-	-	-	-	-	-	-	-	-	DUF968,ERF,Rad52_Rad22
k59_689426_1	1260251.SPISAL_00705	6.73e-53	175.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,1S0KH@1236|Gammaproteobacteria,1WX4D@135613|Chromatiales	135613|Chromatiales	O	PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
k59_61555_1	1121403.AUCV01000056_gene3012	8.67e-63	210.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
k59_571591_1	96561.Dole_0609	3.84e-58	194.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2MI9Q@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_493483_1	331869.BAL199_28635	2.01e-51	171.0	COG1028@1|root,COG1028@2|Bacteria,1R3TE@1224|Proteobacteria,2U55K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_61581_1	1167006.UWK_01836	5.43e-71	223.0	COG1801@1|root,COG1801@2|Bacteria,1N4QE@1224|Proteobacteria,42PDW@68525|delta/epsilon subdivisions,2WK6H@28221|Deltaproteobacteria,2MJ8J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
k59_1007968_1	1385517.N800_15070	6.58e-139	427.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X41A@135614|Xanthomonadales	135614|Xanthomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1080299_1	94624.Bpet3245	9.19e-80	251.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,3T219@506|Alcaligenaceae	28216|Betaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_728542_1	227377.CBU_1862	1.72e-47	164.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,1JDP3@118969|Legionellales	118969|Legionellales	C	4Fe-4S single cluster domain	yjeK	-	-	ko:K19810	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k59_61606_1	740709.A10D4_09504	3.62e-50	175.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,2QFBT@267893|Idiomarinaceae	1236|Gammaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_2362,iG2583_1286.G2583_2541,iUTI89_1310.UTI89_C2293,ic_1306.c2547	Histidinol_dh
k59_1007999_1	9541.XP_005589973.1	2.68e-138	394.0	COG0102@1|root,KOG3204@2759|Eukaryota,38EAZ@33154|Opisthokonta,3BBA1@33208|Metazoa,3CZ32@33213|Bilateria,486IR@7711|Chordata,48US8@7742|Vertebrata,3JDF4@40674|Mammalia,35H2B@314146|Euarchontoglires,4M605@9443|Primates,36220@314294|Cercopithecoidea	33208|Metazoa	J	ribosomal protein	RPL13A	GO:0000184,GO:0000956,GO:0002181,GO:0002237,GO:0002376,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006955,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0007275,GO:0007423,GO:0008104,GO:0008150,GO:0008152,GO:0008407,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009653,GO:0009719,GO:0009887,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010212,GO:0010224,GO:0010243,GO:0010332,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0014070,GO:0014074,GO:0015031,GO:0015833,GO:0015934,GO:0016070,GO:0016071,GO:0016477,GO:0017148,GO:0019222,GO:0019439,GO:0019538,GO:0022416,GO:0022625,GO:0022626,GO:0023052,GO:0030323,GO:0030324,GO:0030595,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032268,GO:0032269,GO:0032496,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0033993,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034613,GO:0034641,GO:0034644,GO:0034645,GO:0034655,GO:0035295,GO:0040011,GO:0042221,GO:0042330,GO:0042592,GO:0042886,GO:0043043,GO:0043170,GO:0043207,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043603,GO:0043604,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045087,GO:0045184,GO:0045947,GO:0046483,GO:0046683,GO:0046700,GO:0046907,GO:0048246,GO:0048513,GO:0048519,GO:0048523,GO:0048731,GO:0048856,GO:0048870,GO:0050789,GO:0050794,GO:0050896,GO:0050900,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051591,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0060326,GO:0060425,GO:0060541,GO:0065007,GO:0065008,GO:0070727,GO:0070887,GO:0070972,GO:0071214,GO:0071310,GO:0071320,GO:0071345,GO:0071346,GO:0071407,GO:0071417,GO:0071478,GO:0071479,GO:0071480,GO:0071482,GO:0071493,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0080090,GO:0090150,GO:0090304,GO:0097159,GO:0097452,GO:0097529,GO:0104004,GO:1901193,GO:1901194,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1904688,GO:1904689,GO:1905517,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766	-	ko:K02872	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
k59_1120388_1	768671.ThimaDRAFT_1155	6.17e-20	88.6	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1WX6T@135613|Chromatiales	135613|Chromatiales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
k59_1120388_2	765912.Thimo_0935	2.34e-18	86.7	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1WWPM@135613|Chromatiales	135613|Chromatiales	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
k59_454022_1	626887.J057_18130	1.75e-81	255.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,4643J@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_649538_1	644968.DFW101_3359	6.2e-10	61.2	2F9C1@1|root,341NY@2|Bacteria,1NXYC@1224|Proteobacteria,430UA@68525|delta/epsilon subdivisions,2WW49@28221|Deltaproteobacteria,2M8XW@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_649538_2	439235.Dalk_3421	3.07e-25	101.0	COG2197@1|root,COG4871@1|root,COG2197@2|Bacteria,COG4871@2|Bacteria,1R098@1224|Proteobacteria,42VR6@68525|delta/epsilon subdivisions,2WRMH@28221|Deltaproteobacteria,2MMX4@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	FeS,GerE
k59_534850_1	717773.Thicy_1674	1.99e-06	49.3	COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,4603J@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k59_767447_1	1298593.TOL_3421	6.37e-53	182.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XIS2@135619|Oceanospirillales	135619|Oceanospirillales	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_298211_2	43989.cce_4142	2.82e-09	60.8	COG1595@1|root,COG1595@2|Bacteria,1G0QM@1117|Cyanobacteria,3KHB8@43988|Cyanothece	1117|Cyanobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigG	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_221424_1	1121396.KB893013_gene3689	3.71e-74	233.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_885354_1	1267005.KB911258_gene442	7.18e-12	70.5	COG3203@1|root,COG3203@2|Bacteria,1R626@1224|Proteobacteria,2VGUQ@28211|Alphaproteobacteria,3N9I8@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_102693_1	1485545.JQLW01000008_gene1995	4.43e-83	255.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_1,Glycos_transf_2
k59_649590_1	706587.Desti_0964	8.7e-109	345.0	COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,42P6X@68525|delta/epsilon subdivisions,2WK8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
k59_22823_1	349521.HCH_01127	3.39e-38	144.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1XHY0@135619|Oceanospirillales	135619|Oceanospirillales	E	Peptide ABC transporter substrate-binding protein	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k59_493600_1	1340493.JNIF01000004_gene1116	7.79e-20	84.0	2E7HP@1|root,33206@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1475)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1475
k59_692717_1	439235.Dalk_3266	6.68e-96	314.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_1162722_1	670307.HYPDE_34178	2.91e-34	122.0	COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,2TU5M@28211|Alphaproteobacteria,3N6N3@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	MA20_36560	-	-	-	-	-	-	-	-	-	-	-	NYN
k59_1162722_2	1123354.AUDR01000017_gene101	4.1e-05	47.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,1KTC0@119069|Hydrogenophilales	119069|Hydrogenophilales	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k59_926509_1	9606.ENSP00000385410	3.52e-72	239.0	KOG2992@1|root,KOG2992@2759|Eukaryota,38DH8@33154|Opisthokonta,3BDT2@33208|Metazoa,3CXCN@33213|Bilateria,4873I@7711|Chordata,492VK@7742|Vertebrata,3JER7@40674|Mammalia,35NPU@314146|Euarchontoglires,4MIEV@9443|Primates,4MSF6@9604|Hominidae	33208|Metazoa	Y	SRP40, C-terminal domain	NOLC1	GO:0000154,GO:0000278,GO:0000451,GO:0001042,GO:0001510,GO:0001650,GO:0001837,GO:0002119,GO:0002164,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0005048,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005732,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006364,GO:0006396,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006970,GO:0006996,GO:0006997,GO:0007000,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007568,GO:0008134,GO:0008139,GO:0008150,GO:0008152,GO:0008284,GO:0008286,GO:0008340,GO:0009058,GO:0009059,GO:0009303,GO:0009451,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009791,GO:0009792,GO:0009888,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010259,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0014029,GO:0014031,GO:0014032,GO:0014033,GO:0015030,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016604,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0022613,GO:0023052,GO:0030154,GO:0030515,GO:0030532,GO:0031167,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031428,GO:0031429,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032386,GO:0032501,GO:0032502,GO:0032774,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0033157,GO:0033218,GO:0033979,GO:0034248,GO:0034470,GO:0034512,GO:0034513,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0040024,GO:0042127,GO:0042221,GO:0042254,GO:0042277,GO:0042306,GO:0043009,GO:0043170,GO:0043175,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043434,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044452,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046822,GO:0046982,GO:0046983,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048646,GO:0048731,GO:0048762,GO:0048856,GO:0048863,GO:0048864,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051223,GO:0051246,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0060341,GO:0060485,GO:0065007,GO:0070013,GO:0070063,GO:0070201,GO:0070887,GO:0071310,GO:0071375,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0072588,GO:0080090,GO:0090087,GO:0090304,GO:0097159,GO:0097659,GO:0098781,GO:0120114,GO:0140110,GO:1900180,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902680,GO:1903506,GO:1903508,GO:1903827,GO:1904589,GO:1990904,GO:2000112,GO:2001141	-	ko:K11294	ko05130,map05130	-	-	-	ko00000,ko00001,ko03009,ko03036	-	-	-	SRP40_C
k59_574902_1	237368.SCABRO_03172	2.17e-167	488.0	28NDD@1|root,2ZBG6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_1162732_2	1463853.JOHW01000011_gene3529	2.38e-21	94.7	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria	201174|Actinobacteria	C	CoA-binding domain protein	acdA1	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_652645_1	335543.Sfum_3618	3.93e-38	135.0	2FD46@1|root,3456H@2|Bacteria,1NZPE@1224|Proteobacteria,43224@68525|delta/epsilon subdivisions,2WWH1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_64893_2	1168065.DOK_16018	1.87e-51	173.0	COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria,1J51Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
k59_301463_1	526225.Gobs_2522	6.57e-47	158.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4ERK6@85013|Frankiales	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_614617_1	338966.Ppro_3708	4.36e-42	150.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_926540_2	290397.Adeh_2176	3.1e-11	63.5	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2WIMS@28221|Deltaproteobacteria,2Z0ES@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_926541_1	1121456.ATVA01000018_gene310	7.47e-07	50.4	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,2M7ZG@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	mechanosensitive ion channel	mscS-2	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_627270_1	392499.Swit_2318	1.3e-34	129.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2K0PV@204457|Sphingomonadales	204457|Sphingomonadales	C	dehydratase	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
k59_627270_2	1122138.AQUZ01000002_gene1886	6.76e-28	113.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4DP2R@85009|Propionibacteriales	201174|Actinobacteria	EG	Dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
k59_157074_1	335283.Neut_0814	3.31e-44	150.0	COG1192@1|root,COG1192@2|Bacteria,1MWH3@1224|Proteobacteria,2VMD8@28216|Betaproteobacteria,373RH@32003|Nitrosomonadales	28216|Betaproteobacteria	D	ATPase MipZ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_509688_1	481448.Minf_2098	1.68e-36	140.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,37GCZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_823209_2	349124.Hhal_2371	1.18e-36	136.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1WXA3@135613|Chromatiales	135613|Chromatiales	U	General secretion pathway protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
k59_744831_1	1454004.AW11_02457	2.21e-16	79.7	COG3614@1|root,COG5002@1|root,COG3614@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2VP0K@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
k59_744831_2	1190603.AJYD01000060_gene1462	1.19e-26	103.0	COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,1S9XI@1236|Gammaproteobacteria,1Y0YC@135623|Vibrionales	135623|Vibrionales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_313810_2	61853.ENSNLEP00000002358	5.14e-307	841.0	COG1985@1|root,KOG0303@2759|Eukaryota,38DGC@33154|Opisthokonta,3BCGZ@33208|Metazoa,3CSIZ@33213|Bilateria,481XB@7711|Chordata,48XMT@7742|Vertebrata,3J8Z4@40674|Mammalia,35E4C@314146|Euarchontoglires,4M5TY@9443|Primates	33208|Metazoa	Z	phagolysosome assembly	CORO1A	GO:0001772,GO:0001775,GO:0001776,GO:0001845,GO:0001891,GO:0001894,GO:0001906,GO:0001909,GO:0002228,GO:0002252,GO:0002260,GO:0002263,GO:0002285,GO:0002323,GO:0002366,GO:0002376,GO:0002443,GO:0002449,GO:0002520,GO:0002521,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0003674,GO:0003779,GO:0003785,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005856,GO:0005884,GO:0005886,GO:0005911,GO:0005938,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006887,GO:0006897,GO:0006909,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007010,GO:0007015,GO:0007033,GO:0007040,GO:0007154,GO:0007155,GO:0007165,GO:0007166,GO:0007275,GO:0007525,GO:0007527,GO:0008022,GO:0008064,GO:0008092,GO:0008150,GO:0008284,GO:0008360,GO:0009605,GO:0009607,GO:0009620,GO:0009719,GO:0009987,GO:0010033,GO:0010522,GO:0010639,GO:0010941,GO:0010959,GO:0012505,GO:0015629,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0016477,GO:0016482,GO:0017022,GO:0022407,GO:0022409,GO:0022603,GO:0022604,GO:0022607,GO:0022610,GO:0023052,GO:0030001,GO:0030027,GO:0030029,GO:0030030,GO:0030036,GO:0030054,GO:0030097,GO:0030098,GO:0030101,GO:0030139,GO:0030154,GO:0030155,GO:0030217,GO:0030334,GO:0030335,GO:0030424,GO:0030595,GO:0030832,GO:0030833,GO:0030863,GO:0030864,GO:0031252,GO:0031338,GO:0031339,GO:0031410,GO:0031589,GO:0031982,GO:0032036,GO:0032271,GO:0032420,GO:0032421,GO:0032426,GO:0032501,GO:0032502,GO:0032535,GO:0032796,GO:0032879,GO:0032940,GO:0032944,GO:0032946,GO:0032956,GO:0032970,GO:0032991,GO:0033043,GO:0034097,GO:0034762,GO:0034765,GO:0038179,GO:0038180,GO:0040011,GO:0040012,GO:0040017,GO:0042102,GO:0042110,GO:0042127,GO:0042129,GO:0042221,GO:0042267,GO:0042330,GO:0042592,GO:0042802,GO:0042803,GO:0042981,GO:0042995,GO:0043005,GO:0043029,GO:0043066,GO:0043067,GO:0043069,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043269,GO:0043299,GO:0043320,GO:0043523,GO:0043524,GO:0043548,GO:0044085,GO:0044087,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045055,GO:0045087,GO:0045321,GO:0045335,GO:0045785,GO:0046649,GO:0046903,GO:0046907,GO:0046983,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0048871,GO:0048872,GO:0048873,GO:0050670,GO:0050671,GO:0050789,GO:0050793,GO:0050794,GO:0050832,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0050900,GO:0050918,GO:0051015,GO:0051049,GO:0051051,GO:0051125,GO:0051126,GO:0051128,GO:0051129,GO:0051179,GO:0051234,GO:0051249,GO:0051251,GO:0051270,GO:0051272,GO:0051279,GO:0051282,GO:0051493,GO:0051494,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051924,GO:0060249,GO:0060326,GO:0060341,GO:0060548,GO:0060627,GO:0061061,GO:0061502,GO:0065007,GO:0065008,GO:0070663,GO:0070665,GO:0070670,GO:0070838,GO:0070848,GO:0070887,GO:0070925,GO:0071310,GO:0071345,GO:0071353,GO:0071363,GO:0071495,GO:0071840,GO:0071944,GO:0072511,GO:0080171,GO:0090066,GO:0090382,GO:0097435,GO:0097458,GO:0097708,GO:0098542,GO:0098657,GO:0098858,GO:0098862,GO:0098927,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099568,GO:0110053,GO:0120025,GO:0120036,GO:0120038,GO:1901214,GO:1901215,GO:1902903,GO:1902904,GO:1903037,GO:1903039,GO:1903169,GO:1904062,GO:1990089,GO:1990090,GO:2000145,GO:2000147	-	ko:K13882,ko:K13886	ko04145,ko05152,map04145,map05152	-	-	-	ko00000,ko00001,ko04131,ko04147,ko04812	-	-	-	DUF1899,Trimer_CC,WD40,WD40_4
k59_705671_1	1042375.AFPL01000023_gene1657	1.22e-64	213.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,4649V@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_392237_1	697282.Mettu_0353	5.01e-52	171.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_940794_1	1454202.PPBDW_120349___1	1.17e-21	90.1	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1S8YK@1236|Gammaproteobacteria,1XXD4@135623|Vibrionales	135623|Vibrionales	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_196319_1	1121405.dsmv_3396	2.56e-52	180.0	COG4656@1|root,COG4656@2|Bacteria,1QMZ4@1224|Proteobacteria,42NJ5@68525|delta/epsilon subdivisions,2WKCG@28221|Deltaproteobacteria,2MIQX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,RnfC_N
k59_470601_1	768671.ThimaDRAFT_1748	1.32e-28	110.0	COG0650@1|root,COG0650@2|Bacteria,1QE37@1224|Proteobacteria,1RZJC@1236|Gammaproteobacteria,1WWZT@135613|Chromatiales	135613|Chromatiales	C	pfam nadh	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_470601_2	768671.ThimaDRAFT_1749	1.74e-61	195.0	COG0377@1|root,COG0377@2|Bacteria,1Q273@1224|Proteobacteria,1S0ZH@1236|Gammaproteobacteria,1WXWF@135613|Chromatiales	135613|Chromatiales	C	PFAM NADH Ubiquinone	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_39545_1	1122194.AUHU01000006_gene628	1.73e-106	313.0	COG0463@1|root,COG0463@2|Bacteria,1QX0V@1224|Proteobacteria,1T32V@1236|Gammaproteobacteria,4647P@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
k59_1058267_1	1047013.AQSP01000134_gene1362	8.43e-100	306.0	2DBU2@1|root,2ZB3S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_274714_1	1234595.C725_2875	1.47e-72	236.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2TQXH@28211|Alphaproteobacteria,4BQU5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
k59_509786_1	1121403.AUCV01000002_gene499	4.59e-63	215.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2MIQB@213118|Desulfobacterales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_1175806_1	1123514.KB905899_gene779	1.57e-62	203.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,460RS@72273|Thiotrichales	72273|Thiotrichales	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
k59_1058329_1	96561.Dole_2849	7.49e-77	242.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2MHWD@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
k59_603_2	717785.HYPMC_3257	1.95e-152	442.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,3N8ZI@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_509823_1	555779.Dthio_PD0885	4.86e-36	136.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,2MG21@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	glutamate synthase alpha subunit	gltS	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_509823_2	215803.DB30_5888	8.71e-07	52.4	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2WKJ1@28221|Deltaproteobacteria,2YU9U@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
k59_1175846_1	1122169.AREN01000004_gene424	3.13e-58	201.0	COG1196@1|root,COG1196@2|Bacteria,1MXPN@1224|Proteobacteria,1S0WY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_588269_1	1163408.UU9_01759	2.7e-119	389.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales	135614|Xanthomonadales	T	Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_431547_1	1121447.JONL01000001_gene467	4.24e-44	165.0	COG0642@1|root,COG0834@1|root,COG3290@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG3290@2|Bacteria,1NXDJ@1224|Proteobacteria,43BMJ@68525|delta/epsilon subdivisions,2WUEV@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HATPase_c,HisKA,Hpt,PAS_4,Response_reg,SBP_bac_3,dCache_1
k59_1136857_1	1187851.A33M_3528	5.18e-84	262.0	COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Xaa-Pro aminopeptidase	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
k59_665_1	96561.Dole_1193	6.57e-68	224.0	COG0427@1|root,COG0454@1|root,COG0427@2|Bacteria,COG0456@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
k59_509885_1	706587.Desti_0219	8.47e-105	319.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1,6.2.1.32	ko:K01895,ko:K08295	ko00010,ko00620,ko00627,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00627,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R00982,R01354	RC00004,RC00012,RC00043,RC00070,RC00174,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1175887_1	768671.ThimaDRAFT_4048	2.38e-17	86.3	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1WZGS@135613|Chromatiales	135613|Chromatiales	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k59_940986_1	450851.PHZ_c2406	9.92e-61	197.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TREJ@28211|Alphaproteobacteria,2KFW4@204458|Caulobacterales	204458|Caulobacterales	C	Dehydrogenase	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_1019278_1	644282.Deba_0261	1.1e-15	80.5	COG0778@1|root,COG1146@1|root,COG0778@2|Bacteria,COG1146@2|Bacteria,1R42D@1224|Proteobacteria,42Q57@68525|delta/epsilon subdivisions,2WNIW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_7,Fer4_9,Nitroreductase
k59_509895_1	1463900.JOIX01000078_gene6657	1.73e-58	193.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_274839_1	981384.AEYW01000014_gene153	1.95e-90	279.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
k59_1058423_1	335543.Sfum_0443	1.82e-49	167.0	COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria,42VJ7@68525|delta/epsilon subdivisions,2WS0Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
k59_700_1	1125863.JAFN01000001_gene1211	1.29e-79	250.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,43BFT@68525|delta/epsilon subdivisions,2X6U5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding_C_2
k59_1019310_2	399741.Spro_2787	6.3e-11	62.0	COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,402CS@613|Serratia	1236|Gammaproteobacteria	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016741,GO:0016765,GO:0022607,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k59_235737_1	207559.Dde_0721	3.47e-56	198.0	COG2172@1|root,COG2208@1|root,COG2972@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG2972@2|Bacteria,1QUX7@1224|Proteobacteria,42ZQY@68525|delta/epsilon subdivisions,2WUWY@28221|Deltaproteobacteria,2MGWA@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	histidine kinase HAMP region domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,HATPase_c_2,SpoIIE
k59_1019319_1	1273538.G159_10640	8.81e-49	175.0	COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,26D3Q@186818|Planococcaceae	91061|Bacilli	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.1.3.21,1.1.5.3	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	-	R00846,R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
k59_1058457_1	948106.AWZT01000053_gene1578	2.58e-82	251.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2VNGT@28216|Betaproteobacteria,1K5H7@119060|Burkholderiaceae	28216|Betaproteobacteria	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
k59_1058457_2	671143.DAMO_2381	3.6e-05	47.4	COG0719@1|root,COG0719@2|Bacteria,2NPGC@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufD	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	UPF0051
k59_705872_1	309807.SRU_0721	5.04e-60	200.0	COG1232@1|root,COG1232@2|Bacteria,4NEPC@976|Bacteroidetes,1FJ99@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k59_392465_1	857087.Metme_2146	2.79e-13	74.3	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1XDKW@135618|Methylococcales	135618|Methylococcales	NU	Neisseria PilC beta-propeller domain	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_196560_1	1121935.AQXX01000095_gene2582	3.34e-75	242.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria	1224|Proteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483,ko:K11183	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
k59_705894_1	349521.HCH_03351	6.48e-34	125.0	COG1305@1|root,COG1305@2|Bacteria,1MVAG@1224|Proteobacteria,1RMXM@1236|Gammaproteobacteria,1XP16@135619|Oceanospirillales	135619|Oceanospirillales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
k59_314055_1	1049564.TevJSym_as00320	1.44e-91	275.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1J5TZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0501 Zn-dependent protease with chaperone function	Z012_09445	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_509961_1	323261.Noc_1083	5.62e-36	138.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1X0CC@135613|Chromatiales	135613|Chromatiales	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
k59_862696_1	1517416.IDAT_01220	1.49e-10	65.9	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,2QFRW@267893|Idiomarinaceae	1236|Gammaproteobacteria	K	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_862696_2	1500893.JQNB01000001_gene976	0.000886	40.8	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1X4A7@135614|Xanthomonadales	135614|Xanthomonadales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_1215248_1	1265505.ATUG01000003_gene40	1.22e-61	196.0	COG0310@1|root,COG0310@2|Bacteria,1RJRC@1224|Proteobacteria,42QZ5@68525|delta/epsilon subdivisions,2WMQX@28221|Deltaproteobacteria,2MJJ5@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
k59_705919_1	335543.Sfum_3100	3.75e-39	146.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,2MQZI@213462|Syntrophobacterales	28221|Deltaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_786_1	27679.XP_003922723.1	2.37e-258	708.0	28RVX@1|root,2QQIA@2759|Eukaryota,39PYF@33154|Opisthokonta,3BI1J@33208|Metazoa,3CTW3@33213|Bilateria,482SF@7711|Chordata,48WXE@7742|Vertebrata,3J7MW@40674|Mammalia,35CTM@314146|Euarchontoglires,4MH3R@9443|Primates	33208|Metazoa	T	Pleckstrin	PLEK	GO:0000981,GO:0001726,GO:0001775,GO:0002244,GO:0002376,GO:0002520,GO:0002576,GO:0002790,GO:0003674,GO:0003700,GO:0005080,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006109,GO:0006355,GO:0006357,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0006810,GO:0006887,GO:0006904,GO:0006950,GO:0006996,GO:0007010,GO:0007154,GO:0007155,GO:0007165,GO:0007166,GO:0007186,GO:0007229,GO:0007275,GO:0007596,GO:0007599,GO:0008064,GO:0008104,GO:0008150,GO:0008152,GO:0008277,GO:0008289,GO:0008361,GO:0009306,GO:0009611,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010468,GO:0010543,GO:0010556,GO:0010562,GO:0010563,GO:0010572,GO:0010638,GO:0010646,GO:0010648,GO:0010675,GO:0010677,GO:0010919,GO:0010920,GO:0010921,GO:0010922,GO:0010924,GO:0010925,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016192,GO:0019219,GO:0019220,GO:0019222,GO:0019637,GO:0019899,GO:0019900,GO:0019901,GO:0022406,GO:0022610,GO:0023051,GO:0023052,GO:0023057,GO:0030029,GO:0030030,GO:0030036,GO:0030097,GO:0030154,GO:0030168,GO:0030193,GO:0030194,GO:0030832,GO:0030834,GO:0030836,GO:0030845,GO:0030865,GO:0030866,GO:0031252,GO:0031253,GO:0031256,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031334,GO:0031529,GO:0031532,GO:0032101,GO:0032231,GO:0032233,GO:0032501,GO:0032502,GO:0032535,GO:0032587,GO:0032940,GO:0032956,GO:0032970,GO:0033036,GO:0033043,GO:0033623,GO:0033625,GO:0034109,GO:0035091,GO:0035303,GO:0035306,GO:0035556,GO:0042060,GO:0042802,GO:0042803,GO:0042886,GO:0042995,GO:0043085,GO:0043167,GO:0043168,GO:0043243,GO:0043244,GO:0043254,GO:0043255,GO:0043325,GO:0044087,GO:0044089,GO:0044093,GO:0044237,GO:0044238,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045184,GO:0045744,GO:0045912,GO:0045936,GO:0045937,GO:0046486,GO:0046488,GO:0046903,GO:0046983,GO:0048278,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048585,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050817,GO:0050818,GO:0050820,GO:0050848,GO:0050849,GO:0050865,GO:0050867,GO:0050878,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051252,GO:0051336,GO:0051345,GO:0051493,GO:0051495,GO:0051640,GO:0051641,GO:0051716,GO:0060255,GO:0060305,GO:0061041,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070493,GO:0070527,GO:0070528,GO:0070560,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0090066,GO:0090303,GO:0098590,GO:0098609,GO:0110053,GO:0120025,GO:0120036,GO:0120038,GO:0140029,GO:0140056,GO:0140110,GO:1900046,GO:1900048,GO:1901879,GO:1901881,GO:1901981,GO:1902531,GO:1902532,GO:1902903,GO:1902905,GO:1902930,GO:1902931,GO:1902936,GO:1903034,GO:1903036,GO:1903506,GO:2000112,GO:2001141	-	ko:K19993	-	-	-	-	ko00000,ko04131	-	-	-	DEP,PH
k59_431706_1	388413.ALPR1_15039	1.43e-22	96.7	COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,47JE7@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
k59_431706_2	1242864.D187_002953	1.37e-65	215.0	COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,437U8@68525|delta/epsilon subdivisions,2X33W@28221|Deltaproteobacteria,2YU3R@29|Myxococcales	28221|Deltaproteobacteria	C	Flavin-binding monooxygenase-like	ethA	-	-	-	-	-	-	-	-	-	-	-	FMO-like,NAD_binding_8
k59_1019374_1	1187851.A33M_3528	4.14e-132	387.0	COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Xaa-Pro aminopeptidase	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
k59_235828_1	1207063.P24_05209	4.9e-89	272.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TU67@28211|Alphaproteobacteria,2JRJM@204441|Rhodospirillales	204441|Rhodospirillales	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_39799_1	59196.RICGR_1381	6.18e-18	77.8	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1JF1P@118969|Legionellales	118969|Legionellales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_39799_2	395493.BegalDRAFT_1786	3.31e-13	68.9	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,460JB@72273|Thiotrichales	72273|Thiotrichales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
k59_862735_1	298653.Franean1_7022	8.26e-46	164.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4ES6Y@85013|Frankiales	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_814_1	10181.XP_004840436.1	7.43e-63	203.0	COG5277@1|root,KOG0676@2759|Eukaryota,38C0D@33154|Opisthokonta,3BBGP@33208|Metazoa,3CRBJ@33213|Bilateria,480DQ@7711|Chordata,4944Y@7742|Vertebrata,3JEDP@40674|Mammalia,35F5M@314146|Euarchontoglires,4Q1SI@9989|Rodentia	33208|Metazoa	Z	postsynaptic cytoskeleton organization	ACTB	GO:0000079,GO:0000123,GO:0000902,GO:0000904,GO:0001654,GO:0001725,GO:0001932,GO:0001933,GO:0002102,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005856,GO:0005886,GO:0005912,GO:0005924,GO:0005925,GO:0005938,GO:0006469,GO:0006928,GO:0006950,GO:0006996,GO:0007010,GO:0007275,GO:0007399,GO:0007409,GO:0007423,GO:0007623,GO:0008092,GO:0008134,GO:0008150,GO:0009605,GO:0009612,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009892,GO:0009987,GO:0010033,GO:0010046,GO:0010243,GO:0010563,GO:0010605,GO:0014069,GO:0014070,GO:0015629,GO:0016020,GO:0016043,GO:0019220,GO:0019222,GO:0019894,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022898,GO:0030027,GO:0030029,GO:0030030,GO:0030036,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030424,GO:0030863,GO:0030957,GO:0031175,GO:0031248,GO:0031252,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031974,GO:0031981,GO:0032091,GO:0032268,GO:0032269,GO:0032279,GO:0032409,GO:0032432,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033673,GO:0034762,GO:0035267,GO:0035690,GO:0035770,GO:0035902,GO:0036146,GO:0036464,GO:0040011,GO:0042221,GO:0042325,GO:0042326,GO:0042493,GO:0042641,GO:0042802,GO:0042995,GO:0043005,GO:0043010,GO:0043086,GO:0043189,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043393,GO:0043549,GO:0044092,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044451,GO:0044456,GO:0044464,GO:0045121,GO:0045202,GO:0045859,GO:0045936,GO:0048468,GO:0048511,GO:0048513,GO:0048519,GO:0048523,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050789,GO:0050790,GO:0050794,GO:0050808,GO:0050896,GO:0050998,GO:0051049,GO:0051098,GO:0051100,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0051602,GO:0051621,GO:0051674,GO:0051716,GO:0051726,GO:0060041,GO:0060255,GO:0061478,GO:0061564,GO:0065007,GO:0065009,GO:0070013,GO:0070161,GO:0070887,GO:0071214,GO:0071257,GO:0071310,GO:0071407,GO:0071417,GO:0071495,GO:0071840,GO:0071900,GO:0071944,GO:0072749,GO:0080090,GO:0097237,GO:0097433,GO:0097458,GO:0097517,GO:0098589,GO:0098794,GO:0098805,GO:0098857,GO:0098918,GO:0098973,GO:0098974,GO:0098984,GO:0099173,GO:0099186,GO:0099188,GO:0099568,GO:0099572,GO:0104004,GO:0120025,GO:0120036,GO:0120039,GO:1901328,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902493,GO:1902494,GO:1902562,GO:1904029,GO:1904030,GO:1990234,GO:1990904	-	ko:K05692	ko04015,ko04145,ko04210,ko04390,ko04391,ko04510,ko04520,ko04530,ko04611,ko04670,ko04714,ko04745,ko04810,ko04919,ko04921,ko05100,ko05110,ko05130,ko05131,ko05132,ko05164,ko05205,ko05225,ko05410,ko05412,ko05414,ko05416,ko05418,map04015,map04145,map04210,map04390,map04391,map04510,map04520,map04530,map04611,map04670,map04714,map04745,map04810,map04919,map04921,map05100,map05110,map05130,map05131,map05132,map05164,map05205,map05225,map05410,map05412,map05414,map05416,map05418	-	-	-	ko00000,ko00001,ko03019,ko03021,ko03029,ko03036,ko04147,ko04812	-	-	-	Actin
k59_79069_1	257313.BP0822	6.36e-18	85.1	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,3T2HZ@506|Alcaligenaceae	28216|Betaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_79069_2	331869.BAL199_29340	4.65e-42	152.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	N-methylhydantoinase B acetone carboxylase alpha subunit	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
k59_705956_1	1122194.AUHU01000003_gene2266	5.67e-06	49.3	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,1S2Z2@1236|Gammaproteobacteria,466WX@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	dithiol-disulfide isomerase involved in polyketide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
k59_705956_2	291985.CCSI01000001_gene1815	1.23e-17	83.6	COG0596@1|root,COG0596@2|Bacteria,1N5ZI@1224|Proteobacteria,2TS7X@28211|Alphaproteobacteria,2K2T4@204457|Sphingomonadales	204457|Sphingomonadales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_784352_1	761193.Runsl_2787	3.07e-32	134.0	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47QEI@768503|Cytophagia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
k59_784358_1	1121904.ARBP01000006_gene3890	3.64e-18	86.3	COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,47JBH@768503|Cytophagia	976|Bacteroidetes	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
k59_784358_2	301.JNHE01000003_gene1903	7.16e-07	50.8	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,1RR7X@1236|Gammaproteobacteria,1YDGK@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	ygcE	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
k59_431775_1	391615.ABSJ01000002_gene497	4.16e-107	316.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,1J4PR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_549309_2	1121405.dsmv_1402	6.73e-15	76.6	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42QD3@68525|delta/epsilon subdivisions,2WKMQ@28221|Deltaproteobacteria,2MK2X@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Phage tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
k59_627718_2	1294273.roselon_02454	4.03e-05	45.8	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG0524 Sugar kinases, ribokinase family	pfkB	-	2.7.1.20,2.7.1.4	ko:K00847,ko:K00856	ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100	-	R00185,R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_862798_1	314278.NB231_13571	8.49e-67	208.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1WWRQ@135613|Chromatiales	135613|Chromatiales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_1177755_1	187272.Mlg_1359	3.75e-105	317.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1WWB4@135613|Chromatiales	135613|Chromatiales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_887074_2	7213.XP_004532713.1	6.61e-66	220.0	COG0187@1|root,KOG0355@2759|Eukaryota,39WG1@33154|Opisthokonta,3BNSE@33208|Metazoa,3DDSJ@33213|Bilateria,42CD5@6656|Arthropoda,3SQ7B@50557|Insecta	33208|Metazoa	B	DNA gyrase C-terminal domain, beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_730112_1	671143.DAMO_3064	2.56e-70	225.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	yghO	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	-
k59_537299_1	1121405.dsmv_0499	1.71e-101	312.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2MIF0@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0470	CPT,CbiA,GATase_3
k59_807335_1	869213.JCM21142_93849	7.07e-32	118.0	COG0723@1|root,COG0723@2|Bacteria,4PNQJ@976|Bacteroidetes,47SP8@768503|Cytophagia	976|Bacteroidetes	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
k59_807335_2	292459.STH3147	8.42e-22	95.5	COG1290@1|root,COG1290@2|Bacteria,1USWS@1239|Firmicutes,2501X@186801|Clostridia	186801|Clostridia	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
k59_223657_1	395494.Galf_2147	2e-36	127.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,2VSDU@28216|Betaproteobacteria,44VUZ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
k59_260649_1	144197.XP_008282458.1	7.1e-11	67.0	COG0174@1|root,KOG0683@2759|Eukaryota,39EXA@33154|Opisthokonta,3BAVA@33208|Metazoa,3CZQ0@33213|Bilateria,487J9@7711|Chordata,48V7E@7742|Vertebrata,49VVA@7898|Actinopterygii	33208|Metazoa	E	Lengsin, lens protein with glutamine synthetase domain	LGSN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Gln-synt_C
k59_422238_1	9361.ENSDNOP00000009892	0.0	919.0	COG5256@1|root,KOG0052@2759|Eukaryota,38G33@33154|Opisthokonta,3BB5I@33208|Metazoa,3CZIS@33213|Bilateria,487AZ@7711|Chordata,490DH@7742|Vertebrata,3J48S@40674|Mammalia	33208|Metazoa	J	translation elongation factor activity	EEF1A1	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005853,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K03231,ko:K13199	ko03013,ko05134,map03013,map05134	-	-	-	ko00000,ko00001,ko03012,ko03016,ko03019,ko03041,ko04131,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_769237_1	998088.B565_3072	7.68e-52	174.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1Y3GJ@135624|Aeromonadales	135624|Aeromonadales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
k59_1200678_2	745014.OMB55_00013260	7.35e-41	149.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,1RNBI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_537324_1	1151117.AJLF01000001_gene1353	1.27e-09	62.4	COG2414@1|root,arCOG00709@2157|Archaea,2Y7HG@28890|Euryarchaeota,243R1@183968|Thermococci	183968|Thermococci	C	aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_537324_2	1089551.KE386572_gene4535	4.69e-07	50.4	COG4948@1|root,COG4948@2|Bacteria,1NI9F@1224|Proteobacteria,2TVSH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
k59_378176_1	177439.DP2866	2.52e-94	290.0	COG0535@1|root,COG0535@2|Bacteria,1QWQ6@1224|Proteobacteria,43BV0@68525|delta/epsilon subdivisions,2X75Z@28221|Deltaproteobacteria,2MPKQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_299969_1	1095769.CAHF01000021_gene924	5.61e-33	128.0	COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,2VPMI@28216|Betaproteobacteria,476H5@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
k59_495337_1	309807.SRU_2042	1.26e-76	242.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1FIWE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	HP	ThiF family	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
k59_422300_1	1121875.KB907548_gene1616	9.45e-55	191.0	COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia	976|Bacteroidetes	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
k59_455853_1	316274.Haur_2069	2.34e-77	242.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
k59_495353_1	1469613.JT55_02505	9.11e-106	337.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,2TQXU@28211|Alphaproteobacteria,3FDZT@34008|Rhodovulum	28211|Alphaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
k59_925153_1	228410.NE1342	2.18e-66	214.0	COG4671@1|root,COG4671@2|Bacteria,1QXHK@1224|Proteobacteria,2WCXY@28216|Betaproteobacteria,373VG@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k59_887164_1	1385935.N836_03240	4.03e-07	54.7	2EM9G@1|root,33EYK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_455878_1	1411685.U062_01261	2.02e-81	266.0	COG2182@1|root,COG2182@2|Bacteria,1MU3H@1224|Proteobacteria,1RY48@1236|Gammaproteobacteria,1J6B3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_537414_1	713586.KB900536_gene3056	2.59e-98	301.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1WW6G@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_691348_1	883078.HMPREF9695_01903	5.71e-74	240.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2TQPM@28211|Alphaproteobacteria,3JU26@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_300057_1	561175.KB894094_gene1543	2.92e-05	51.6	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4EN4W@85012|Streptosporangiales	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
k59_651351_1	1278309.KB907099_gene2933	8.48e-87	271.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1QYEW@1224|Proteobacteria,1T3PI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Pyr_redox_3
k59_847871_1	1232437.KL662020_gene705	3.25e-48	167.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_260781_1	526222.Desal_0710	1.78e-56	191.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria,2M8S3@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_613137_1	123899.JPQP01000023_gene3146	1.39e-10	62.4	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2VM30@28216|Betaproteobacteria,3T8QC@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_1161369_1	261292.Nit79A3_2868	1.42e-13	73.2	COG2200@1|root,COG3279@1|root,COG2200@2|Bacteria,COG3279@2|Bacteria,1N299@1224|Proteobacteria,2VKSH@28216|Betaproteobacteria,372CK@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,Response_reg
k59_925237_2	935848.JAEN01000008_gene571	2.76e-25	98.2	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2UCKH@28211|Alphaproteobacteria,2PYKC@265|Paracoccus	28211|Alphaproteobacteria	E	Phosphoribosyl-AMP cyclohydrolase	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
k59_378340_2	1049564.TevJSym_ak00930	1.88e-68	214.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,1J5G3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
k59_1161372_1	177437.HRM2_08840	2.39e-116	352.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
k59_455966_1	319003.Bra1253DRAFT_02462	1.37e-10	66.6	COG0477@1|root,COG2814@2|Bacteria,1QUY6@1224|Proteobacteria,2TWZ0@28211|Alphaproteobacteria,3JQS0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_104796_1	9593.ENSGGOP00000018832	2e-137	402.0	COG0631@1|root,KOG0699@2759|Eukaryota,38CQG@33154|Opisthokonta,3B9BA@33208|Metazoa,3CY5N@33213|Bilateria,481MX@7711|Chordata,492M6@7742|Vertebrata,3J7K3@40674|Mammalia,35HGY@314146|Euarchontoglires,4MEX5@9443|Primates,4N649@9604|Hominidae	33208|Metazoa	T	Sigma factor PP2C-like phosphatases	PPM1G	GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007049,GO:0007050,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0022402,GO:0031974,GO:0031981,GO:0035970,GO:0036211,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045786,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051726,GO:0065007,GO:0070013,GO:0071704,GO:0140096,GO:1901564	3.1.3.16	ko:K17499	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C
k59_537519_1	61853.ENSNLEP00000004425	7.33e-107	325.0	COG0526@1|root,KOG0190@2759|Eukaryota,38GTB@33154|Opisthokonta,3BDMQ@33208|Metazoa,3CXFK@33213|Bilateria,48028@7711|Chordata,490T6@7742|Vertebrata,3J2ZN@40674|Mammalia,35FQT@314146|Euarchontoglires,4M5YZ@9443|Primates	33208|Metazoa	O	Protein disulfide isomerase family A member 4	PDIA4	GO:0002790,GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005790,GO:0006457,GO:0006810,GO:0006950,GO:0008104,GO:0008150,GO:0008152,GO:0009306,GO:0009986,GO:0009987,GO:0012505,GO:0015031,GO:0015036,GO:0015037,GO:0015833,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0031974,GO:0032940,GO:0032991,GO:0033036,GO:0033554,GO:0034663,GO:0034976,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055114,GO:0061077,GO:0065007,GO:0070013,GO:0071702,GO:0071705,GO:0140096,GO:1903332,GO:1903334	5.3.4.1	ko:K09582	ko04141,ko04918,ko05110,map04141,map04918,map05110	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04131	-	-	-	Thioredoxin,Thioredoxin_6
k59_966020_1	1121405.dsmv_0540	3.8e-59	193.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,2MIV4@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_1243750_1	472759.Nhal_2032	6.89e-64	211.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1WXBQ@135613|Chromatiales	135613|Chromatiales	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
k59_1122412_1	998674.ATTE01000001_gene4154	1.41e-85	257.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,1RPU6@1236|Gammaproteobacteria,460P4@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit II	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_730306_1	1461580.CCAS010000078_gene4205	3.68e-08	58.5	COG2865@1|root,COG2865@2|Bacteria,1U2FH@1239|Firmicutes,4IC13@91061|Bacilli,1ZMXX@1386|Bacillus	91061|Bacilli	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
k59_1200874_1	991905.SL003B_1386	5.06e-26	107.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2TSEU@28211|Alphaproteobacteria,4BQFK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	haloacid dehalogenase-like hydrolase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
k59_730330_1	1288298.rosmuc_04036	1.89e-116	344.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TUQT@28211|Alphaproteobacteria,46PY7@74030|Roseovarius	28211|Alphaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_730330_2	1288298.rosmuc_04036	1.45e-06	49.3	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TUQT@28211|Alphaproteobacteria,46PY7@74030|Roseovarius	28211|Alphaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_63569_1	318161.Sden_3449	6.67e-10	57.4	2E3AG@1|root,32Y9Z@2|Bacteria,1NADT@1224|Proteobacteria,1SDGA@1236|Gammaproteobacteria,2QCK4@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_338774_2	1443111.JASG01000004_gene2249	1.28e-59	201.0	COG1012@1|root,COG1012@2|Bacteria,1R528@1224|Proteobacteria,2UNP7@28211|Alphaproteobacteria,3ZWS4@60136|Sulfitobacter	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
k59_730347_2	313612.L8106_09121	8.01e-13	75.9	COG2199@1|root,COG3706@2|Bacteria,1G3NI@1117|Cyanobacteria,1H8P7@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
k59_341195_1	1265313.HRUBRA_01636	3.76e-05	46.6	COG4307@1|root,COG4307@2|Bacteria,1MW31@1224|Proteobacteria,1RRA7@1236|Gammaproteobacteria,1JA5V@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
k59_144399_1	933262.AXAM01000024_gene743	1.85e-73	226.0	COG5266@1|root,COG5266@2|Bacteria,1PVKN@1224|Proteobacteria,42PYV@68525|delta/epsilon subdivisions,2WK42@28221|Deltaproteobacteria,2MIRP@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Domain of unknown function (DUF4198)	-	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	DUF4198
k59_263303_1	1229172.JQFA01000002_gene2596	4.48e-64	213.0	COG0480@1|root,COG0480@2|Bacteria,1G2JV@1117|Cyanobacteria,1H85T@1150|Oscillatoriales	1117|Cyanobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_1124731_1	177437.HRM2_16600	1.31e-97	301.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MJ8N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.12.1.3,1.6.5.2,1.6.5.3	ko:K00124,ko:K00335,ko:K00355,ko:K18331	ko00130,ko00190,ko00630,ko00680,ko01100,ko01110,ko01120,ko01200,ko05200,ko05225,ko05418,map00130,map00190,map00630,map00680,map01100,map01110,map01120,map01200,map05200,map05225,map05418	M00144	R00519,R02964,R03643,R03816,R11945	RC00061,RC00819,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
k59_1203408_1	10181.XP_004844413.1	8.2e-86	281.0	COG1204@1|root,KOG0951@2759|Eukaryota,3ARV9@33154|Opisthokonta,3BYCJ@33208|Metazoa,3CW5J@33213|Bilateria,489T7@7711|Chordata,492SX@7742|Vertebrata,3JD8Y@40674|Mammalia,35AF1@314146|Euarchontoglires,4PUVQ@9989|Rodentia	33208|Metazoa	A	ATP-dependent RNA helicase activity	SNRNP200	GO:0000003,GO:0000245,GO:0000354,GO:0000375,GO:0000377,GO:0000381,GO:0000398,GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005682,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0007276,GO:0007283,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0008380,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019953,GO:0022414,GO:0022607,GO:0022613,GO:0022618,GO:0030532,GO:0031323,GO:0031974,GO:0031981,GO:0032501,GO:0032504,GO:0032991,GO:0034622,GO:0034641,GO:0042623,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043484,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045292,GO:0046483,GO:0046540,GO:0048024,GO:0048232,GO:0048609,GO:0050684,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051704,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0070035,GO:0071013,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097525,GO:0097526,GO:0120114,GO:0140098,GO:1901360,GO:1902494,GO:1903311,GO:1990904	3.6.4.13	ko:K12854	ko03040,map03040	M00354,M00355	-	-	ko00000,ko00001,ko00002,ko01000,ko03041	-	-	-	DEAD,Helicase_C,Sec63
k59_1203436_1	571166.KI421509_gene3587	3.24e-37	134.0	COG5361@1|root,COG5361@2|Bacteria,1NZZJ@1224|Proteobacteria,2TV8A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Protein of unknown function (DUF1254)	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	DUF1214,DUF1254
k59_1084644_1	309799.DICTH_0782	1.18e-62	204.0	COG0017@1|root,COG0017@2|Bacteria	2|Bacteria	J	Asparaginyl-tRNA synthetase	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_1084644_2	1211844.CBLM010000149_gene2219	0.000973	41.6	COG1426@1|root,COG1426@2|Bacteria,1V4WQ@1239|Firmicutes,3VQRG@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
k59_226051_1	933262.AXAM01000011_gene1755	9.9e-47	167.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,2MJ25@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
k59_144445_1	1211115.ALIQ01000046_gene3038	4.55e-14	69.3	COG5588@1|root,COG5588@2|Bacteria,1PZHC@1224|Proteobacteria,2TVVV@28211|Alphaproteobacteria,3NCVG@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
k59_144445_2	990285.RGCCGE502_10516	7.53e-48	155.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2U9QB@28211|Alphaproteobacteria,4BEMP@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the glutaredoxin family. Monothiol subfamily	grlA	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
k59_144445_3	491916.RHECIAT_CH0002397	1.86e-32	114.0	COG0271@1|root,COG0271@2|Bacteria,1R3MM@1224|Proteobacteria,2UBUW@28211|Alphaproteobacteria,4BG4G@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Belongs to the BolA IbaG family	MA20_09125	-	-	-	-	-	-	-	-	-	-	-	BolA
k59_575959_1	1167006.UWK_01225	3.41e-14	70.5	COG4849@1|root,COG4849@2|Bacteria,1RDHG@1224|Proteobacteria,42WAF@68525|delta/epsilon subdivisions,2WRPU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_575959_2	522772.Dacet_0116	7.16e-21	93.2	28W7P@1|root,2ZI89@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_889670_1	1385519.N801_15180	1.38e-54	189.0	COG2232@1|root,COG2232@2|Bacteria,2HPI0@201174|Actinobacteria,4FK2A@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
k59_540648_1	983545.Glaag_3790	3.71e-64	209.0	COG0665@1|root,COG0665@2|Bacteria,1Q9VR@1224|Proteobacteria,1S0R4@1236|Gammaproteobacteria,46A05@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_66076_1	314285.KT71_03457	2.72e-73	228.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,1RS6A@1236|Gammaproteobacteria,1J7ZS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Thiosulfate-oxidizing multienzyme system protein SoxA	soxA	-	1.8.2.2	ko:K17222,ko:K19713	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	-
k59_263369_1	1045855.DSC_09620	3.7e-10	57.8	2ANYG@1|root,2ZGFF@2|Bacteria,1QEQI@1224|Proteobacteria,1TBIU@1236|Gammaproteobacteria,1X94U@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_144458_1	349521.HCH_02593	3.88e-38	140.0	28HN6@1|root,2Z7WJ@2|Bacteria,1R5QB@1224|Proteobacteria,1RNJN@1236|Gammaproteobacteria,1XNCZ@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_616015_1	391593.RCCS2_10425	8.87e-61	198.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TR3F@28211|Alphaproteobacteria,2P1E6@2433|Roseobacter	28211|Alphaproteobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_458449_1	318167.Sfri_2288	2.05e-116	347.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,1T20X@1236|Gammaproteobacteria,2QAVG@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
k59_732743_1	247634.GPB2148_84	2.78e-81	248.0	COG4977@1|root,COG4977@2|Bacteria,1QXFH@1224|Proteobacteria,1T3AI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PAS_4
k59_540670_1	631454.N177_1233	3.44e-19	90.9	COG5375@1|root,COG5375@2|Bacteria,1Q5QB@1224|Proteobacteria,2VCFG@28211|Alphaproteobacteria,1JPH7@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
k59_302545_1	868131.MSWAN_0153	1.86e-36	128.0	COG1720@1|root,arCOG00761@2157|Archaea,2XY3D@28890|Euryarchaeota,23PMX@183925|Methanobacteria	183925|Methanobacteria	S	PFAM Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
k59_302545_2	1173024.KI912148_gene3379	5.42e-55	175.0	2C46F@1|root,32SRD@2|Bacteria,1GDYV@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_968700_1	1121405.dsmv_2822	1.14e-30	124.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2MIS3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_381658_1	933262.AXAM01000222_gene924	9.32e-72	224.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,2MJAD@213118|Desulfobacterales	28221|Deltaproteobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
k59_302560_1	857087.Metme_3155	6.31e-05	45.4	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria,1XECZ@135618|Methylococcales	135618|Methylococcales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
k59_302560_2	1123514.KB905899_gene1981	4.4e-40	145.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,460DA@72273|Thiotrichales	72273|Thiotrichales	Q	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
k59_425661_1	330214.NIDE0942	6.14e-09	61.2	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OMP_b-brl,OmpA
k59_968724_1	748727.CLJU_c16090	3.66e-20	90.9	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,36ERC@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
k59_968724_2	335283.Neut_0135	5.63e-14	69.3	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,371WE@32003|Nitrosomonadales	28216|Betaproteobacteria	EH	PFAM Glutamine amidotransferase class-I	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_158914_1	350054.Mflv_3051	2.24e-31	125.0	COG5361@1|root,COG5361@2|Bacteria,2GRDZ@201174|Actinobacteria,233IZ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_237286_1	309801.trd_0158	1.68e-21	90.1	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE,DrsE_2
k59_41329_1	999141.GME_07684	6.75e-122	358.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1XHCZ@135619|Oceanospirillales	135619|Oceanospirillales	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_590050_1	981384.AEYW01000001_gene1490	1.4e-55	187.0	COG1234@1|root,COG1234@2|Bacteria,1RIJP@1224|Proteobacteria	1224|Proteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_4
k59_1021120_1	311403.Arad_9174	5.19e-07	55.1	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TUMK@28211|Alphaproteobacteria,4B9FV@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_472445_1	349521.HCH_00744	8.43e-127	372.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1XH97@135619|Oceanospirillales	135619|Oceanospirillales	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1022443_1	61853.ENSNLEP00000003275	0.0	1259.0	COG5069@1|root,KOG0046@2759|Eukaryota,38BRY@33154|Opisthokonta,3BD6Z@33208|Metazoa,3CRGP@33213|Bilateria,4830P@7711|Chordata,4964M@7742|Vertebrata,3J23K@40674|Mammalia,35KWV@314146|Euarchontoglires,4MBDN@9443|Primates	33208|Metazoa	Z	Lymphocyte cytosolic protein 1	LCP1	GO:0001726,GO:0001775,GO:0001891,GO:0002102,GO:0002252,GO:0002263,GO:0002285,GO:0002286,GO:0002366,GO:0002376,GO:0003674,GO:0003779,GO:0005102,GO:0005178,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005884,GO:0005886,GO:0005912,GO:0005924,GO:0005925,GO:0006928,GO:0006950,GO:0006955,GO:0006996,GO:0007010,GO:0007015,GO:0007154,GO:0007165,GO:0007166,GO:0008092,GO:0008150,GO:0009611,GO:0009987,GO:0010033,GO:0010638,GO:0010737,GO:0015629,GO:0016020,GO:0016043,GO:0016477,GO:0019221,GO:0019899,GO:0022411,GO:0022607,GO:0022617,GO:0023052,GO:0030029,GO:0030036,GO:0030054,GO:0030055,GO:0030175,GO:0030198,GO:0031252,GO:0031334,GO:0032386,GO:0032432,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033157,GO:0034097,GO:0035556,GO:0035722,GO:0040011,GO:0042110,GO:0042221,GO:0042802,GO:0042995,GO:0043062,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0044085,GO:0044087,GO:0044089,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045321,GO:0046649,GO:0046872,GO:0048518,GO:0048522,GO:0048870,GO:0050789,GO:0050794,GO:0050839,GO:0050896,GO:0051015,GO:0051017,GO:0051020,GO:0051049,GO:0051128,GO:0051130,GO:0051179,GO:0051223,GO:0051639,GO:0051674,GO:0051716,GO:0051764,GO:0060341,GO:0061572,GO:0065007,GO:0070161,GO:0070201,GO:0070671,GO:0070887,GO:0071310,GO:0071345,GO:0071349,GO:0071801,GO:0071803,GO:0071840,GO:0071944,GO:0090087,GO:0097435,GO:0098858,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:1902115,GO:1902117,GO:1903827	-	ko:K17275,ko:K17276,ko:K17336	-	-	-	-	ko00000,ko03400,ko04147,ko04812	-	-	-	CH,EF-hand_1,EF-hand_5,EF-hand_6,EF-hand_7,EF-hand_8
k59_513018_1	1499967.BAYZ01000097_gene4378	7.1e-09	60.1	COG4974@1|root,COG4974@2|Bacteria,2NP4H@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase, N-terminal SAM-like domain	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1139535_1	768671.ThimaDRAFT_0873	1.4e-92	288.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGB@1236|Gammaproteobacteria,1X1MI@135613|Chromatiales	135613|Chromatiales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_1100534_1	765911.Thivi_4072	3.76e-36	128.0	2E2DR@1|root,32XIE@2|Bacteria,1N271@1224|Proteobacteria,1SIHA@1236|Gammaproteobacteria,1X1VU@135613|Chromatiales	135613|Chromatiales	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
k59_943884_2	644282.Deba_1503	1.82e-67	216.0	COG0500@1|root,COG2226@2|Bacteria,1PCH2@1224|Proteobacteria,42M58@68525|delta/epsilon subdivisions,2WK5Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	OQ	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_513077_1	1231185.BAMP01000019_gene2976	2.21e-112	334.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TS1R@28211|Alphaproteobacteria,43HJ6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	Belongs to the thiolase family	fadA	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0033554,GO:0033812,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_669588_2	102232.GLO73106DRAFT_00034210	4.13e-14	75.1	COG0801@1|root,COG0801@2|Bacteria,1G5NF@1117|Cyanobacteria	1117|Cyanobacteria	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
k59_316775_1	1282876.BAOK01000002_gene848	1.63e-93	285.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2UNMP@28211|Alphaproteobacteria,4BT8S@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
k59_1022563_1	640512.BC1003_0664	1.87e-63	210.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2VZNG@28216|Betaproteobacteria,1K6IW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	similarity to GP 3192745	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_747904_1	314345.SPV1_06954	1.87e-62	203.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria	1224|Proteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006996,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009657,GO:0009668,GO:0009987,GO:0010027,GO:0016043,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0061024,GO:0071704,GO:0071840,GO:0072330,GO:1901576	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b1095,iAPECO1_1312.APECO1_176,iB21_1397.B21_01099,iBWG_1329.BWG_0943,iE2348C_1286.E2348C_1187,iEC042_1314.EC042_1165,iEC55989_1330.EC55989_1207,iECABU_c1320.ECABU_c13085,iECBD_1354.ECBD_2506,iECB_1328.ECB_01091,iECDH10B_1368.ECDH10B_1167,iECDH1ME8569_1439.ECDH1ME8569_1030,iECD_1391.ECD_01091,iECED1_1282.ECED1_1238,iECH74115_1262.ECH74115_1474,iECIAI1_1343.ECIAI1_1130,iECIAI39_1322.ECIAI39_2066,iECO103_1326.ECO103_1140,iECO111_1330.ECO111_1372,iECO26_1355.ECO26_1428,iECOK1_1307.ECOK1_1202,iECP_1309.ECP_1087,iECS88_1305.ECS88_1109,iECSE_1348.ECSE_1159,iECSF_1327.ECSF_0994,iECSP_1301.ECSP_1396,iECUMN_1333.ECUMN_1270,iECW_1372.ECW_m1203,iECs_1301.ECs1473,iEKO11_1354.EKO11_2739,iETEC_1333.ETEC_1160,iEcDH1_1363.EcDH1_2552,iEcE24377_1341.EcE24377A_1216,iEcSMS35_1347.EcSMS35_2032,iG2583_1286.G2583_1355,iJO1366.b1095,iJR904.b1095,iLF82_1304.LF82_0607,iNRG857_1313.NRG857_05280,iSF_1195.SF1099,iSFxv_1172.SFxv_1251,iS_1188.S1179,iUMN146_1321.UM146_11850,iWFL_1372.ECW_m1203,iY75_1357.Y75_RS05720,iZ_1308.Z1734,ic_1306.c1365	Ketoacyl-synt_C,ketoacyl-synt
k59_1100607_1	377629.TERTU_2605	4.93e-85	263.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,2PPQ1@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	O	Peptidase family U32 C-terminal domain	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
k59_630363_1	933262.AXAM01000048_gene2576	9.3e-82	259.0	COG0457@1|root,COG1944@1|root,COG0457@2|Bacteria,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,42N4B@68525|delta/epsilon subdivisions,2WJ34@28221|Deltaproteobacteria,2MHRU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8,YcaO
k59_3737_1	459349.CLOAM1042	1.6e-21	96.7	COG2861@1|root,COG2861@2|Bacteria,2NPU5@2323|unclassified Bacteria	2|Bacteria	S	Divergent polysaccharide deacetylase	yibQ	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
k59_1218024_1	203122.Sde_2020	8.13e-62	204.0	COG3067@1|root,COG3067@2|Bacteria,1MV0F@1224|Proteobacteria,1RPE3@1236|Gammaproteobacteria,464PD@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaB	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042221,GO:0042592,GO:0044464,GO:0045851,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1902600	-	ko:K03314	-	-	-	-	ko00000,ko02000	2.A.34.1	-	iECP_1309.ECP_1229,iLF82_1304.LF82_1485,iNRG857_1313.NRG857_06055,iUTI89_1310.UTI89_C1372	NhaB
k59_983312_1	105420.BBPO01000003_gene1201	8.99e-17	79.3	COG1215@1|root,COG1215@2|Bacteria,2GJP7@201174|Actinobacteria,2NG0E@228398|Streptacidiphilus	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_983312_2	1281779.H009_01379	2.32e-10	64.3	COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,2U5F8@28211|Alphaproteobacteria,4BMCQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	isoleucine patch superfamily	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
k59_277842_1	1286106.MPL1_00457	1.37e-15	82.8	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,461X9@72273|Thiotrichales	72273|Thiotrichales	NU	Type IV fimbrial biogenesis protein PilY1	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_1100666_1	1246626.BleG1_2685	5.34e-12	65.1	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,1ZC14@1386|Bacillus	91061|Bacilli	V	ABC transporter, ATP-binding protein	yknY	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1100666_2	1134474.O59_000524	1.32e-36	137.0	COG0577@1|root,COG0577@2|Bacteria,1R88B@1224|Proteobacteria,1S1SX@1236|Gammaproteobacteria,1FHY7@10|Cellvibrio	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_787228_1	743721.Psesu_2212	8.26e-69	231.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,1X39X@135614|Xanthomonadales	135614|Xanthomonadales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
k59_669707_1	1283300.ATXB01000002_gene3125	7.38e-30	115.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S3VR@1236|Gammaproteobacteria,1XDX1@135618|Methylococcales	135618|Methylococcales	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
k59_1022646_1	439235.Dalk_4508	1.94e-22	100.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,2MIKX@213118|Desulfobacterales	28221|Deltaproteobacteria	K	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
k59_591433_2	1410674.JNKU01000008_gene1289	0.000203	44.7	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,3F44K@33958|Lactobacillaceae	91061|Bacilli	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_826452_1	991905.SL003B_3096	1.58e-42	160.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,4BR82@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_944048_1	1410676.JNKL01000003_gene527	2.59e-26	101.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,1Y3QD@135624|Aeromonadales	135624|Aeromonadales	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
k59_944048_2	1265503.KB905161_gene3418	9.49e-29	106.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,2Q6ZN@267889|Colwelliaceae	1236|Gammaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
k59_944048_3	349124.Hhal_0844	3.34e-15	71.2	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1WXYT@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
k59_748010_1	358681.BBR47_16670	8.18e-89	281.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,26R1I@186822|Paenibacillaceae	91061|Bacilli	IQ	PFAM AMP-dependent synthetase and ligase	lcfA	-	6.2.1.3,6.2.1.48	ko:K00666,ko:K01897,ko:K02182,ko:K18661	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_1061363_1	1090320.KB900605_gene2144	9.55e-87	264.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,2K2SD@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_787297_1	754477.Q7C_887	2.76e-88	273.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,45ZTN@72273|Thiotrichales	72273|Thiotrichales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_1218094_1	1215092.PA6_009_00300	8.23e-38	140.0	28JC4@1|root,2Z96S@2|Bacteria,1RI8W@1224|Proteobacteria,1S6FI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	P22 coat protein-protein 5 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1139757_1	1121405.dsmv_0970	6.75e-80	253.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2MIPJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_160378_1	1000565.METUNv1_01567	1.66e-44	156.0	COG2378@1|root,COG2378@2|Bacteria,1P2ZE@1224|Proteobacteria,2VMDI@28216|Betaproteobacteria,2KZTK@206389|Rhodocyclales	206389|Rhodocyclales	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
k59_591494_1	105559.Nwat_0811	1.06e-34	133.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1WWM9@135613|Chromatiales	135613|Chromatiales	O	Cytochrome c-type biogenesis protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_591494_2	991905.SL003B_0248	3.35e-13	68.9	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2TSEW@28211|Alphaproteobacteria,4BQJQ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	CO	Redoxin	ccmG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
k59_277904_1	399739.Pmen_2664	2.98e-48	172.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,1RNB7@1236|Gammaproteobacteria,1YE1R@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Amidohydrolase family	nfdA	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_826513_2	1123073.KB899242_gene961	1.32e-28	115.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1X5UP@135614|Xanthomonadales	135614|Xanthomonadales	G	TRAP-type C4-dicarboxylate transport system, large permease component	dctM	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_513291_1	335543.Sfum_1795	4.3e-109	330.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2MRHE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_473779_1	1035197.HMPREF9999_02315	1.35e-21	97.1	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,2FM9Z@200643|Bacteroidia,1WD4S@1283313|Alloprevotella	976|Bacteroidetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
k59_3869_1	1121937.AUHJ01000048_gene1211	2.5e-82	252.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,46ABE@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DDE domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_944131_1	1280666.ATVS01000025_gene2879	4.4e-25	108.0	COG1472@1|root,COG1619@1|root,COG1472@2|Bacteria,COG1619@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,4BX6E@830|Butyrivibrio	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C,Gram_pos_anchor
k59_1022797_1	177437.HRM2_01750	7.38e-105	316.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2MHPU@213118|Desulfobacterales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
k59_865728_1	296591.Bpro_3427	8.91e-23	103.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VISZ@28216|Betaproteobacteria,4A9ZK@80864|Comamonadaceae	28216|Betaproteobacteria	M	RND efflux system, outer membrane lipoprotein	-	-	-	ko:K18903	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17.3.3	-	-	OEP
k59_630567_1	323848.Nmul_A0590	4.9e-61	197.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,37239@32003|Nitrosomonadales	28216|Betaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_865740_1	1125863.JAFN01000001_gene1039	1.38e-49	176.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k59_3894_1	30611.ENSOGAP00000012559	2.77e-192	556.0	KOG2242@1|root,KOG2242@2759|Eukaryota,38FNX@33154|Opisthokonta,3BD0H@33208|Metazoa,3CRCQ@33213|Bilateria,481JN@7711|Chordata,495WA@7742|Vertebrata,3J5FP@40674|Mammalia,35AJZ@314146|Euarchontoglires,4M60E@9443|Primates	33208|Metazoa	K	AAA domain	HNRNPU	GO:0000122,GO:0000166,GO:0000228,GO:0000375,GO:0000377,GO:0000381,GO:0000398,GO:0000775,GO:0000776,GO:0000803,GO:0000976,GO:0000977,GO:0000978,GO:0000987,GO:0000993,GO:0001012,GO:0001067,GO:0001085,GO:0001091,GO:0001097,GO:0001098,GO:0001099,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003697,GO:0003712,GO:0003714,GO:0003723,GO:0003725,GO:0003727,GO:0003729,GO:0003730,GO:0003779,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005694,GO:0005697,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005856,GO:0005874,GO:0005876,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006397,GO:0006403,GO:0006725,GO:0006807,GO:0007088,GO:0007275,GO:0007346,GO:0007507,GO:0007549,GO:0007623,GO:0008092,GO:0008104,GO:0008134,GO:0008143,GO:0008144,GO:0008150,GO:0008152,GO:0008187,GO:0008284,GO:0008380,GO:0009048,GO:0009410,GO:0009719,GO:0009725,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009986,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010638,GO:0010639,GO:0010911,GO:0010912,GO:0014070,GO:0014706,GO:0015630,GO:0016070,GO:0016071,GO:0016363,GO:0016604,GO:0016607,GO:0017069,GO:0017076,GO:0017130,GO:0019219,GO:0019220,GO:0019222,GO:0019899,GO:0030154,GO:0030496,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031490,GO:0031960,GO:0031974,GO:0031981,GO:0032204,GO:0032205,GO:0032210,GO:0032211,GO:0032501,GO:0032502,GO:0032507,GO:0032553,GO:0032555,GO:0032559,GO:0032781,GO:0032784,GO:0032785,GO:0032870,GO:0032879,GO:0032886,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0033365,GO:0033673,GO:0033993,GO:0034046,GO:0034097,GO:0034243,GO:0034244,GO:0034399,GO:0034504,GO:0034613,GO:0034641,GO:0035051,GO:0035372,GO:0035639,GO:0035690,GO:0035770,GO:0036002,GO:0036094,GO:0036464,GO:0040029,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0042493,GO:0042692,GO:0042802,GO:0043021,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043462,GO:0043484,GO:0043487,GO:0043488,GO:0043489,GO:0043549,GO:0043565,GO:0044087,GO:0044092,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044380,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0044877,GO:0045185,GO:0045595,GO:0045596,GO:0045597,GO:0045598,GO:0045600,GO:0045787,GO:0045840,GO:0045892,GO:0045893,GO:0045931,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0046483,GO:0048024,GO:0048255,GO:0048468,GO:0048511,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0050684,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051233,GO:0051235,GO:0051252,GO:0051253,GO:0051254,GO:0051336,GO:0051338,GO:0051345,GO:0051348,GO:0051384,GO:0051457,GO:0051493,GO:0051641,GO:0051651,GO:0051716,GO:0051726,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0051987,GO:0051988,GO:0055001,GO:0055002,GO:0055006,GO:0055007,GO:0055013,GO:0060236,GO:0060255,GO:0060341,GO:0060537,GO:0061013,GO:0061061,GO:0062033,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070034,GO:0070063,GO:0070507,GO:0070717,GO:0070727,GO:0070887,GO:0070934,GO:0070937,GO:0071013,GO:0071310,GO:0071345,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0072091,GO:0072359,GO:0072595,GO:0072686,GO:0072698,GO:0080090,GO:0090068,GO:0090169,GO:0090224,GO:0090235,GO:0090304,GO:0090335,GO:0090336,GO:0097159,GO:0097327,GO:0097367,GO:0098577,GO:0098687,GO:0099080,GO:0099081,GO:0099122,GO:0099512,GO:0099513,GO:0140110,GO:1901265,GO:1901360,GO:1901363,GO:1901654,GO:1901655,GO:1901673,GO:1901700,GO:1901701,GO:1902115,GO:1902275,GO:1902369,GO:1902373,GO:1902423,GO:1902425,GO:1902494,GO:1902679,GO:1902680,GO:1902889,GO:1903311,GO:1903312,GO:1903506,GO:1903507,GO:1903508,GO:1904356,GO:1904357,GO:1990023,GO:1990280,GO:1990498,GO:1990823,GO:1990830,GO:1990837,GO:1990841,GO:1990845,GO:1990904,GO:2000112,GO:2000113,GO:2000278,GO:2000279,GO:2000371,GO:2000373,GO:2000648,GO:2000736,GO:2000737,GO:2001141,GO:2001251,GO:2001252	-	ko:K12888,ko:K15047,ko:K15698	ko03040,ko05164,map03040,map05164	-	-	-	ko00000,ko00001,ko03041,ko04121	-	-	-	AAA_33,SAP,SPRY
k59_552319_1	504728.K649_04665	1.48e-73	235.0	COG0585@1|root,COG0585@2|Bacteria,1WJ08@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_434649_1	1288826.MSNKSG1_09033	7.24e-14	70.1	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,464DI@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Displays ATPase and GTPase activities	rapZ	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k59_434649_2	713586.KB900536_gene1421	5.17e-51	171.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S02U@1236|Gammaproteobacteria,1WX9F@135613|Chromatiales	135613|Chromatiales	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
k59_865762_1	1266914.ATUK01000016_gene373	3.53e-71	232.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales	135613|Chromatiales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_630593_1	61853.ENSNLEP00000005739	4.17e-122	348.0	COG1528@1|root,KOG2332@2759|Eukaryota,39ZU0@33154|Opisthokonta,3BM9S@33208|Metazoa,3D51N@33213|Bilateria,4887S@7711|Chordata,494Q1@7742|Vertebrata,3JDKH@40674|Mammalia,35A57@314146|Euarchontoglires,4M97E@9443|Primates	33208|Metazoa	P	ferric iron binding	FTL	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005767,GO:0005773,GO:0005775,GO:0005776,GO:0005829,GO:0006810,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006887,GO:0006955,GO:0008043,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0012505,GO:0016192,GO:0019725,GO:0030003,GO:0030139,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0032991,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042221,GO:0042582,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044422,GO:0044424,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044754,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0070288,GO:0071682,GO:0097577,GO:0097708,GO:0098771,GO:0099503	-	ko:K13625	ko04216,ko04217,ko04978,map04216,map04217,map04978	-	-	-	ko00000,ko00001,ko04147	-	-	-	Ferritin
k59_865768_1	439235.Dalk_4147	1.78e-134	385.0	COG0207@1|root,COG0207@2|Bacteria,1Q4ZG@1224|Proteobacteria,42QWZ@68525|delta/epsilon subdivisions,2WMY5@28221|Deltaproteobacteria,2MJKN@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Thymidylate synthase	-	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
k59_278005_1	1235797.C816_00793	1.69e-60	202.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,2N82I@216572|Oscillospiraceae	186801|Clostridia	EG	Psort location Cytoplasmic, score 9.97	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_944229_1	439235.Dalk_3502	5.31e-61	199.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,42NI3@68525|delta/epsilon subdivisions,2WJ6P@28221|Deltaproteobacteria,2MHUH@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_434671_1	1122134.KB893650_gene688	2.97e-88	269.0	COG0482@1|root,COG0482@2|Bacteria,1QV6H@1224|Proteobacteria,1RQSV@1236|Gammaproteobacteria,1XNSX@135619|Oceanospirillales	135619|Oceanospirillales	J	tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_Me_trans
k59_865798_1	1380355.JNIJ01000010_gene1568	1.21e-28	116.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2U0C9@28211|Alphaproteobacteria,3K0B3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
k59_944249_1	1121033.AUCF01000001_gene2215	9.22e-61	197.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2TRIG@28211|Alphaproteobacteria,2JP9M@204441|Rhodospirillales	204441|Rhodospirillales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_434676_1	1396858.Q666_00545	4.92e-113	340.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,464VT@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iAF1260.b2312,iB21_1397.B21_02197,iBWG_1329.BWG_2086,iECBD_1354.ECBD_1347,iECB_1328.ECB_02237,iECDH10B_1368.ECDH10B_2474,iECDH1ME8569_1439.ECDH1ME8569_2250,iECD_1391.ECD_02237,iECIAI1_1343.ECIAI1_2389,iECO103_1326.ECO103_2776,iECO111_1330.ECO111_3060,iECO26_1355.ECO26_3300,iECW_1372.ECW_m2501,iEKO11_1354.EKO11_1453,iETEC_1333.ETEC_2448,iEcDH1_1363.EcDH1_1344,iEcE24377_1341.EcE24377A_2606,iEcolC_1368.EcolC_1340,iJO1366.b2312,iJR904.b2312,iSF_1195.SF2388,iSFxv_1172.SFxv_2633,iSSON_1240.SSON_2370,iS_1188.S2523,iSbBS512_1146.SbBS512_E2690,iUMNK88_1353.UMNK88_2863,iWFL_1372.ECW_m2501,iY75_1357.Y75_RS12125	GATase_6,Pribosyltran
k59_160556_1	457570.Nther_1745	7.68e-27	106.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia	186801|Clostridia	C	radical SAM domain protein	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
k59_1061516_1	504487.JCM19302_1737	1.48e-12	64.7	COG0437@1|root,COG0437@2|Bacteria,4NK7Y@976|Bacteroidetes,1I0UN@117743|Flavobacteriia	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
k59_1061516_2	1158292.JPOE01000002_gene2951	2.13e-68	220.0	COG3301@1|root,COG3301@2|Bacteria,1MXQ9@1224|Proteobacteria,2VXWB@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_1022890_1	335543.Sfum_1171	1.3e-31	122.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MXG@68525|delta/epsilon subdivisions,2WJ6G@28221|Deltaproteobacteria,2MQ3U@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	aminotransferase, class I and II	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1131227_1	713586.KB900536_gene1078	2.65e-19	92.0	COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1X0ZE@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2066)	-	-	-	ko:K09938	-	-	-	-	ko00000	-	-	-	DUF2066
k59_1018485_1	935840.JAEQ01000005_gene1195	4.27e-75	229.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria,43GQY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_582765_1	1267533.KB906740_gene223	4.95e-65	217.0	COG1680@1|root,COG1680@2|Bacteria,3Y3T0@57723|Acidobacteria,2JHSK@204432|Acidobacteriia	204432|Acidobacteriia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_114846_1	1172188.KB911821_gene2078	7.39e-33	133.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
k59_739092_2	1026882.MAMP_02984	2.23e-27	110.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,1S416@1236|Gammaproteobacteria,4616F@72273|Thiotrichales	72273|Thiotrichales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_582793_1	472759.Nhal_1618	1.21e-96	283.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,1RRAN@1236|Gammaproteobacteria,1X04F@135613|Chromatiales	135613|Chromatiales	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_7
k59_114897_1	187272.Mlg_0788	4.26e-90	285.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S321@1236|Gammaproteobacteria,1X2HG@135613|Chromatiales	135613|Chromatiales	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
k59_856513_1	60711.ENSCSAP00000005793	6.57e-94	276.0	29NSV@1|root,2RW3Y@2759|Eukaryota,3AK3A@33154|Opisthokonta,3BZUV@33208|Metazoa,3D7NV@33213|Bilateria,48ETG@7711|Chordata,49BHC@7742|Vertebrata,3JH3G@40674|Mammalia,35QPM@314146|Euarchontoglires,4MN77@9443|Primates,363AS@314294|Cercopithecoidea	33208|Metazoa	S	Brain expressed X-linked 2	BEX2	GO:0001085,GO:0001102,GO:0002052,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005667,GO:0005737,GO:0006355,GO:0006357,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007399,GO:0008134,GO:0008150,GO:0008284,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010720,GO:0010721,GO:0019219,GO:0019222,GO:0022008,GO:0023052,GO:0030154,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032501,GO:0032502,GO:0032991,GO:0033613,GO:0038179,GO:0042127,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044093,GO:0044424,GO:0044464,GO:0045595,GO:0045596,GO:0045597,GO:0045664,GO:0045665,GO:0045893,GO:0045935,GO:0045944,GO:0048011,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051090,GO:0051091,GO:0051093,GO:0051094,GO:0051171,GO:0051173,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051254,GO:0051716,GO:0051960,GO:0051961,GO:0051962,GO:0060255,GO:0060284,GO:0065007,GO:0065009,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0072091,GO:0080090,GO:1902680,GO:1902692,GO:1903506,GO:1903508,GO:2000026,GO:2000112,GO:2000177,GO:2000179,GO:2000648,GO:2001141	-	-	-	-	-	-	-	-	-	-	BEX
k59_1053775_1	29073.XP_008693442.1	1.3e-132	400.0	COG0464@1|root,KOG0730@2759|Eukaryota,38BWW@33154|Opisthokonta,3BIKJ@33208|Metazoa,3CU41@33213|Bilateria,48961@7711|Chordata,496BU@7742|Vertebrata,3J6P9@40674|Mammalia,3EUIU@33554|Carnivora	33208|Metazoa	O	Valosin containing protein	VCP	GO:0000003,GO:0000166,GO:0000226,GO:0000323,GO:0000502,GO:0000731,GO:0000785,GO:0000902,GO:0000904,GO:0001775,GO:0002020,GO:0002082,GO:0002165,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003006,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005764,GO:0005766,GO:0005767,GO:0005773,GO:0005775,GO:0005776,GO:0005783,GO:0005789,GO:0005811,GO:0005829,GO:0006139,GO:0006140,GO:0006163,GO:0006259,GO:0006281,GO:0006301,GO:0006302,GO:0006457,GO:0006464,GO:0006486,GO:0006487,GO:0006508,GO:0006511,GO:0006515,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006887,GO:0006888,GO:0006914,GO:0006919,GO:0006950,GO:0006955,GO:0006974,GO:0006986,GO:0006996,GO:0007010,GO:0007017,GO:0007029,GO:0007030,GO:0007033,GO:0007034,GO:0007040,GO:0007041,GO:0007154,GO:0007165,GO:0007275,GO:0007276,GO:0007277,GO:0007279,GO:0007317,GO:0007349,GO:0007399,GO:0007552,GO:0007610,GO:0007626,GO:0008047,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0008333,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009109,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009605,GO:0009607,GO:0009615,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010243,GO:0010256,GO:0010498,GO:0010562,GO:0010604,GO:0010623,GO:0010646,GO:0010647,GO:0010648,GO:0010918,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016032,GO:0016043,GO:0016192,GO:0016197,GO:0016236,GO:0016320,GO:0016358,GO:0016462,GO:0016504,GO:0016567,GO:0016579,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017144,GO:0018130,GO:0018193,GO:0018196,GO:0018279,GO:0019058,GO:0019079,GO:0019219,GO:0019220,GO:0019222,GO:0019362,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019725,GO:0019899,GO:0019902,GO:0019903,GO:0019904,GO:0019941,GO:0019953,GO:0019985,GO:0022008,GO:0022411,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030030,GO:0030111,GO:0030141,GO:0030154,GO:0030162,GO:0030163,GO:0030177,GO:0030178,GO:0030182,GO:0030234,GO:0030433,GO:0030554,GO:0030808,GO:0030810,GO:0030968,GO:0030970,GO:0031175,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031334,GO:0031399,GO:0031401,GO:0031410,GO:0031593,GO:0031625,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0031984,GO:0032268,GO:0032270,GO:0032434,GO:0032436,GO:0032446,GO:0032501,GO:0032502,GO:0032504,GO:0032509,GO:0032510,GO:0032527,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032940,GO:0032984,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033554,GO:0034098,GO:0034214,GO:0034404,GO:0034613,GO:0034620,GO:0034641,GO:0034645,GO:0034654,GO:0034655,GO:0034774,GO:0034976,GO:0035069,GO:0035096,GO:0035578,GO:0035639,GO:0035770,GO:0035800,GO:0035861,GO:0035966,GO:0035967,GO:0036094,GO:0036211,GO:0036230,GO:0036435,GO:0036464,GO:0036503,GO:0036513,GO:0042119,GO:0042175,GO:0042176,GO:0042221,GO:0042287,GO:0042288,GO:0042325,GO:0042327,GO:0042391,GO:0042582,GO:0042592,GO:0042726,GO:0042728,GO:0042802,GO:0042886,GO:0042981,GO:0043009,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043161,GO:0043167,GO:0043168,GO:0043170,GO:0043186,GO:0043207,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043280,GO:0043281,GO:0043299,GO:0043312,GO:0043412,GO:0043413,GO:0043457,GO:0043467,GO:0043523,GO:0043525,GO:0043531,GO:0043632,GO:0043900,GO:0043902,GO:0043903,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044389,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044427,GO:0044428,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044754,GO:0044877,GO:0045055,GO:0045169,GO:0045184,GO:0045321,GO:0045495,GO:0045595,GO:0045732,GO:0045838,GO:0045862,GO:0045935,GO:0045937,GO:0045981,GO:0045995,GO:0046034,GO:0046434,GO:0046483,GO:0046496,GO:0046596,GO:0046598,GO:0046700,GO:0046716,GO:0046903,GO:0046907,GO:0048193,GO:0048284,GO:0048468,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048583,GO:0048584,GO:0048585,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048731,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050790,GO:0050792,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051186,GO:0051187,GO:0051234,GO:0051239,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051336,GO:0051345,GO:0051603,GO:0051641,GO:0051649,GO:0051704,GO:0051707,GO:0051716,GO:0051788,GO:0051881,GO:0052547,GO:0052548,GO:0055085,GO:0055086,GO:0060033,GO:0060205,GO:0060249,GO:0060255,GO:0060281,GO:0060284,GO:0060293,GO:0060341,GO:0060828,GO:0061024,GO:0061025,GO:0061134,GO:0061136,GO:0061857,GO:0061919,GO:0062012,GO:0062013,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070085,GO:0070646,GO:0070647,GO:0070727,GO:0070841,GO:0070842,GO:0070887,GO:0070987,GO:0071218,GO:0071310,GO:0071702,GO:0071704,GO:0071705,GO:0071712,GO:0071840,GO:0071897,GO:0071985,GO:0072387,GO:0072389,GO:0072521,GO:0072524,GO:0080090,GO:0080171,GO:0090085,GO:0090090,GO:0090174,GO:0090263,GO:0090304,GO:0090734,GO:0097159,GO:0097352,GO:0097367,GO:0097708,GO:0098586,GO:0098772,GO:0098796,GO:0098827,GO:0099503,GO:0101002,GO:0120036,GO:0120039,GO:0140030,GO:1900371,GO:1900373,GO:1900542,GO:1900544,GO:1901135,GO:1901137,GO:1901214,GO:1901216,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901698,GO:1901800,GO:1902494,GO:1902875,GO:1903003,GO:1903004,GO:1903006,GO:1903007,GO:1903050,GO:1903052,GO:1903320,GO:1903322,GO:1903362,GO:1903364,GO:1903429,GO:1903513,GO:1903578,GO:1903580,GO:1903715,GO:1903862,GO:1903900,GO:1903902,GO:1904288,GO:1904580,GO:1904813,GO:1904949,GO:1905368,GO:1905369,GO:1905879,GO:1990381,GO:1990730,GO:1990904,GO:2000026,GO:2000058,GO:2000060,GO:2000116,GO:2000152,GO:2000158,GO:2000241,GO:2001056,GO:2001169,GO:2001171	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N,Vps4_C
k59_547153_1	648757.Rvan_0465	9.11e-75	236.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2TSEA@28211|Alphaproteobacteria,3N6R0@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_308829_1	768671.ThimaDRAFT_2128	1.69e-82	256.0	COG5361@1|root,COG5361@2|Bacteria,1NZZJ@1224|Proteobacteria,1RSI3@1236|Gammaproteobacteria,1X0BE@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_348070_1	396588.Tgr7_0944	6.46e-62	200.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1WXTC@135613|Chromatiales	135613|Chromatiales	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_232593_1	948106.AWZT01000002_gene6396	1.29e-47	165.0	COG0687@1|root,COG0687@2|Bacteria,1MU0I@1224|Proteobacteria,2VM38@28216|Betaproteobacteria,1KHQ5@119060|Burkholderiaceae	28216|Betaproteobacteria	E	substrate-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
k59_856571_1	237727.NAP1_09762	4.2e-07	52.0	COG2267@1|root,COG2303@1|root,COG2267@2|Bacteria,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,2U3F9@28211|Alphaproteobacteria,2K2U7@204457|Sphingomonadales	204457|Sphingomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_856571_2	43229.XP_007719130.1	1.34e-12	70.9	COG1028@1|root,KOG1208@2759|Eukaryota,39YJ9@33154|Opisthokonta,3Q304@4751|Fungi,3RK1K@4890|Ascomycota,20THA@147545|Eurotiomycetes,3MSBR@451870|Chaetothyriomycetidae	4751|Fungi	Q	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1018620_1	1121403.AUCV01000026_gene2380	2.23e-75	242.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1RGKE@1224|Proteobacteria,43BX6@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,HisKA_2,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Pkinase,STAS,SpoIIE
k59_464907_1	744980.TRICHSKD4_4797	1.39e-63	213.0	COG0330@1|root,COG0330@2|Bacteria,1MW1D@1224|Proteobacteria,2TRE5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_816267_2	56780.SYN_00591	6.26e-70	217.0	COG1225@1|root,COG1225@2|Bacteria,1N9JS@1224|Proteobacteria,42R82@68525|delta/epsilon subdivisions,2WMVA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
k59_388468_1	30611.ENSOGAP00000016705	8.12e-154	433.0	COG5040@1|root,KOG0841@2759|Eukaryota,38CKG@33154|Opisthokonta,3B9IN@33208|Metazoa,3CZZY@33213|Bilateria,483EV@7711|Chordata,48V6J@7742|Vertebrata,3J6JB@40674|Mammalia,35IGR@314146|Euarchontoglires,4MFGC@9443|Primates	33208|Metazoa	O	Tyrosine 3-monooxygenase tryptophan 5-monooxygenase activation protein, gamma	YWHAG	GO:0000086,GO:0000278,GO:0001932,GO:0001933,GO:0003674,GO:0003779,GO:0004857,GO:0004860,GO:0005080,GO:0005102,GO:0005159,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006469,GO:0006605,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007006,GO:0007049,GO:0007154,GO:0007165,GO:0007275,GO:0007346,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0008092,GO:0008104,GO:0008150,GO:0008426,GO:0009719,GO:0009725,GO:0009892,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010389,GO:0010563,GO:0010564,GO:0010605,GO:0010638,GO:0010646,GO:0010647,GO:0010821,GO:0010822,GO:0010941,GO:0010942,GO:0015031,GO:0015833,GO:0016043,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022008,GO:0022402,GO:0022406,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030031,GO:0030154,GO:0030234,GO:0030291,GO:0030971,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031982,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0033036,GO:0033043,GO:0033673,GO:0034613,GO:0042221,GO:0042325,GO:0042326,GO:0042802,GO:0042886,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043209,GO:0043226,GO:0043227,GO:0043434,GO:0043549,GO:0044085,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0045184,GO:0045595,GO:0045664,GO:0045859,GO:0045936,GO:0046902,GO:0046907,GO:0048167,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050804,GO:0050896,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0051640,GO:0051641,GO:0051649,GO:0051716,GO:0051726,GO:0051960,GO:0060255,GO:0060271,GO:0060284,GO:0060322,GO:0060341,GO:0061024,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070727,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:0071840,GO:0071900,GO:0071901,GO:0072359,GO:0080090,GO:0090559,GO:0097711,GO:0098772,GO:0099177,GO:0120031,GO:0120036,GO:0140056,GO:1900739,GO:1900740,GO:1901028,GO:1901030,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901987,GO:1901990,GO:1902749,GO:1903047,GO:1903747,GO:1903749,GO:1903827,GO:1903829,GO:1904951,GO:1905475,GO:1905477,GO:1990782,GO:2000026,GO:2001233,GO:2001235	-	ko:K16198	ko04110,ko04114,ko04151,ko04390,ko05169,ko05203,map04110,map04114,map04151,map04390,map05169,map05203	-	-	-	ko00000,ko00001,ko01009,ko03400,ko04147	-	-	-	14-3-3
k59_308893_1	1457393.AZ09_04095	2.95e-15	77.8	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,2JRZP@204441|Rhodospirillales	204441|Rhodospirillales	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_308893_2	1121405.dsmv_2999	3.07e-09	58.5	COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,1R7US@1224|Proteobacteria,42PFT@68525|delta/epsilon subdivisions,2WMBJ@28221|Deltaproteobacteria,2MJ1Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,TPP_enzyme_C
k59_856624_2	1255043.TVNIR_3026	5e-94	290.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1WWX1@135613|Chromatiales	135613|Chromatiales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_778576_1	693661.Arcve_1076	4.27e-09	58.2	COG1148@1|root,COG1908@1|root,arCOG02235@2157|Archaea,arCOG02476@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,FlpD,Pyr_redox_2
k59_778576_2	1265505.ATUG01000002_gene2656	1.42e-36	126.0	COG1908@1|root,COG1908@2|Bacteria,1N4XV@1224|Proteobacteria,42UTE@68525|delta/epsilon subdivisions,2WQE3@28221|Deltaproteobacteria,2MKMT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
k59_739225_1	335543.Sfum_0259	3.53e-89	282.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2MR9G@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
k59_1252170_1	1410665.JNKR01000018_gene38	7.29e-69	226.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4H2A6@909932|Negativicutes	909932|Negativicutes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
k59_1053919_1	246200.SPO2406	1.22e-54	175.0	COG3415@1|root,COG3415@2|Bacteria,1PERR@1224|Proteobacteria,2UHBZ@28211|Alphaproteobacteria,4NDMV@97050|Ruegeria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1053919_2	246200.SPO2407	3.95e-21	87.4	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_1131358_1	1121875.KB907556_gene567	8.83e-23	99.8	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes	976|Bacteroidetes	P	K -dependent Na Ca exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
k59_388536_1	1121405.dsmv_0256	9.04e-05	45.8	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_739254_1	94624.Bpet4199	7.79e-52	174.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2VNCV@28216|Betaproteobacteria,3T7GG@506|Alcaligenaceae	28216|Betaproteobacteria	S	Aldo keto reductases, related to diketogulonate reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
k59_388538_1	765914.ThisiDRAFT_2385	1.59e-83	265.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1WWI1@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_934346_1	1122201.AUAZ01000003_gene1871	5.2e-82	265.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,463XQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_778596_1	1128912.GMES_0380	2.69e-54	191.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1T3CM@1236|Gammaproteobacteria,46DAI@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	VRR_NUC	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,VRR_NUC
k59_1252185_1	371731.Rsw2DRAFT_0369	2.18e-89	277.0	COG1328@1|root,COG1328@2|Bacteria,1N1EN@1224|Proteobacteria,2TU2D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Protein of unknown function (DUF3029)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3029
k59_1131379_1	482537.XP_008579048.1	1.54e-138	392.0	COG0638@1|root,KOG0180@2759|Eukaryota,38GZR@33154|Opisthokonta,3B9UW@33208|Metazoa,3D1MR@33213|Bilateria,480D4@7711|Chordata,493SM@7742|Vertebrata,3JFM1@40674|Mammalia,35NW7@314146|Euarchontoglires	33208|Metazoa	O	subunit, beta	PSMB3	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005839,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016579,GO:0016787,GO:0019538,GO:0019774,GO:0019941,GO:0030163,GO:0031974,GO:0031981,GO:0032991,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0051603,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K02735	ko03050,map03050	M00337,M00340	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
k59_348219_1	9606.ENSP00000410059	2.01e-129	385.0	COG2092@1|root,KOG1668@2759|Eukaryota,38GFD@33154|Opisthokonta,3BGZQ@33208|Metazoa,3CZS5@33213|Bilateria,481AF@7711|Chordata,48WRI@7742|Vertebrata,3J578@40674|Mammalia,35H7H@314146|Euarchontoglires,4M7XN@9443|Primates,4MTKR@9604|Hominidae	33208|Metazoa	K	EF-1 guanine nucleotide exchange domain	EEF1D	GO:0001650,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0005853,GO:0006139,GO:0006351,GO:0006412,GO:0006414,GO:0006518,GO:0006725,GO:0006807,GO:0008134,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009299,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010467,GO:0010941,GO:0016070,GO:0016071,GO:0018130,GO:0019438,GO:0019538,GO:0031072,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0033613,GO:0034641,GO:0034645,GO:0034654,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070013,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:0104004,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K15410	ko05168,map05168	-	-	-	ko00000,ko00001,ko03012	-	-	-	EF-1_beta_acid,EF1_GNE
k59_189963_1	1217718.ALOU01000007_gene1259	3.7e-61	199.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2VM5U@28216|Betaproteobacteria,1KF02@119060|Burkholderiaceae	28216|Betaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k59_504569_1	869213.JCM21142_93668	1.17e-24	103.0	2E5T9@1|root,330HK@2|Bacteria,4NWGF@976|Bacteroidetes	976|Bacteroidetes	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
k59_1171021_1	351348.Maqu_3303	1.34e-68	219.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,466XK@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Glycolate oxidase FAD binding subunit	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_308987_1	1122137.AQXF01000003_gene2151	6.13e-75	240.0	COG1288@1|root,COG1288@2|Bacteria,1MY1J@1224|Proteobacteria,2U2WN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	C4-dicarboxylate	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
k59_856699_1	335543.Sfum_1166	8.44e-114	336.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria,2MQWC@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	oxidoreductase, alpha subunit	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_1210267_1	1469245.JFBG01000016_gene965	5.28e-39	137.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria,1X0T0@135613|Chromatiales	135613|Chromatiales	O	PFAM Cytochrome c oxidase assembly protein CtaG Cox11	-	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
k59_388582_1	879212.DespoDRAFT_00390	1.52e-44	155.0	COG1639@1|root,COG1639@2|Bacteria,1RKNA@1224|Proteobacteria,42TE8@68525|delta/epsilon subdivisions,2WPCE@28221|Deltaproteobacteria,2MPXW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_151086_1	443254.Marpi_0837	4.38e-59	201.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	amyA	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
k59_1252257_1	1121015.N789_10340	2.4e-34	134.0	COG2114@1|root,COG2114@2|Bacteria,1R86S@1224|Proteobacteria,1SMMJ@1236|Gammaproteobacteria,1XA3K@135614|Xanthomonadales	135614|Xanthomonadales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071,Guanylate_cyc
k59_115071_1	1049564.TevJSym_aa01140	8.67e-53	173.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,1S2AY@1236|Gammaproteobacteria,1J762@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
k59_348315_1	555779.Dthio_PD2211	4.58e-33	116.0	2E3J3@1|root,32YHH@2|Bacteria,1NBJI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76085_2	933262.AXAM01000077_gene1698	2.62e-33	117.0	2APA5@1|root,31EC7@2|Bacteria,1RHMQ@1224|Proteobacteria,42UND@68525|delta/epsilon subdivisions,2WQK4@28221|Deltaproteobacteria,2MM23@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_820129_1	477974.Daud_0906	7.94e-54	189.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,260AT@186807|Peptococcaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_1174718_1	333138.LQ50_21010	3.79e-102	309.0	COG0006@1|root,COG0006@2|Bacteria,1TSN0@1239|Firmicutes,4HCA3@91061|Bacilli,1ZAZR@1386|Bacillus	91061|Bacilli	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
k59_37548_1	335543.Sfum_1977	1.09e-88	288.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_508378_1	1049564.TevJSym_at00390	8.13e-80	254.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1J4IR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	-	ko:K03688	-	-	-	-	ko00000	-	-	iYL1228.KPN_04331	ABC1
k59_352047_2	717231.Flexsi_0440	1.62e-60	198.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1214074_1	482537.XP_008572169.1	5.84e-145	410.0	KOG3252@1|root,KOG3252@2759|Eukaryota,38GM1@33154|Opisthokonta,3BGWS@33208|Metazoa,3D277@33213|Bilateria,483EZ@7711|Chordata,490YY@7742|Vertebrata,3J9W3@40674|Mammalia,359IC@314146|Euarchontoglires	33208|Metazoa	J	ribosome binding	EIF3K	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005852,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010941,GO:0010942,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042981,GO:0043043,GO:0043065,GO:0043067,GO:0043068,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901566,GO:1901576	-	ko:K15028	-	-	-	-	ko00000,ko03012	-	-	-	CSN8_PSD8_EIF3K
k59_663967_1	439235.Dalk_4372	1.01e-69	217.0	COG0491@1|root,COG0491@2|Bacteria,1MUT2@1224|Proteobacteria,42MVA@68525|delta/epsilon subdivisions,2WKBW@28221|Deltaproteobacteria,2MJ8X@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_273932_1	420246.GTNG_0756	1.3e-15	79.7	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,1WG9A@129337|Geobacillus	91061|Bacilli	L	PFAM Integrase, catalytic core	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_1095187_1	1123247.AUIJ01000056_gene2963	1.85e-108	322.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k59_1095187_2	2340.JV46_04900	9.7e-18	79.3	COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,1RR0H@1236|Gammaproteobacteria,1J6S2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Haloacid dehalogenase-like hydrolase	hadL	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_663987_1	1096930.L284_01180	3.77e-88	266.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2TRTM@28211|Alphaproteobacteria,2K3YT@204457|Sphingomonadales	204457|Sphingomonadales	Q	hydrolase	-	-	3.7.1.20	ko:K16165	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
k59_508444_1	1232437.KL662043_gene2213	1.19e-47	172.0	COG0591@1|root,COG5002@1|root,COG0591@2|Bacteria,COG5002@2|Bacteria,1QTSW@1224|Proteobacteria,43CHB@68525|delta/epsilon subdivisions,2X7SG@28221|Deltaproteobacteria,2MJ3Z@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,SSF,SpoIIE
k59_860627_1	289376.THEYE_A0738	6.93e-12	65.1	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_860627_2	1379281.AVAG01000012_gene1502	6.9e-34	121.0	2DDIC@1|root,32U1K@2|Bacteria,1NDK2@1224|Proteobacteria,42VX8@68525|delta/epsilon subdivisions,2WSEV@28221|Deltaproteobacteria,2MC5D@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1214109_1	1090320.KB900605_gene569	3.25e-33	128.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2TR9R@28211|Alphaproteobacteria,2K1GF@204457|Sphingomonadales	204457|Sphingomonadales	P	Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_782511_1	1042375.AFPL01000023_gene1657	7.31e-48	169.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,4649V@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_743310_1	1162668.LFE_0043	2.96e-65	212.0	COG0674@1|root,COG0674@2|Bacteria,3J0HY@40117|Nitrospirae	40117|Nitrospirae	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_743310_2	1440774.Y900_027895	1.14e-09	58.9	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,2GJ0A@201174|Actinobacteria,236N6@1762|Mycobacteriaceae	201174|Actinobacteria	C	glutamate synthase	preT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
k59_1214127_1	927658.AJUM01000022_gene1216	9.9e-64	204.0	COG0428@1|root,COG0428@2|Bacteria,4NGQ8@976|Bacteroidetes,2FQF3@200643|Bacteroidia,3XIIG@558415|Marinilabiliaceae	976|Bacteroidetes	P	ZIP Zinc transporter	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
k59_900574_1	555088.DealDRAFT_1432	5.1e-20	92.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,42KAR@68298|Syntrophomonadaceae	186801|Clostridia	C	Electron transfer flavoprotein, alpha subunit	fixB	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4,Fer4_6,Fer4_7
k59_820242_1	596154.Alide2_4496	3.24e-91	281.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,4AAKQ@80864|Comamonadaceae	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_1230281_2	1304874.JAFY01000002_gene840	1.63e-09	62.0	COG1593@1|root,COG1593@2|Bacteria,3T9YH@508458|Synergistetes	508458|Synergistetes	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
k59_248855_1	243231.GSU1907	7.84e-69	216.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,43SK7@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_52507_1	335543.Sfum_2463	1.24e-90	274.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42SJQ@68525|delta/epsilon subdivisions,2WPH7@28221|Deltaproteobacteria,2MRF5@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_523329_1	1304885.AUEY01000052_gene1554	1.42e-56	198.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria,2MJCC@213118|Desulfobacterales	28221|Deltaproteobacteria	NTU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,T2SSE,T2SSE_N
k59_757847_1	1234364.AMSF01000033_gene322	4.2e-68	221.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1X38X@135614|Xanthomonadales	135614|Xanthomonadales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
k59_875475_1	1265503.KB905166_gene680	2.43e-18	82.8	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,1RMX9@1236|Gammaproteobacteria	1224|Proteobacteria	I	the in vivo substrate is	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
k59_875475_2	1035308.AQYY01000002_gene505	3.23e-05	48.1	COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes,24HQS@186801|Clostridia,262JF@186807|Peptococcaceae	186801|Clostridia	T	esterase of the alpha-beta hydrolase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_366657_1	338969.Rfer_2152	2.06e-44	157.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,2VJCC@28216|Betaproteobacteria,4AD5U@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_953964_1	1265505.ATUG01000001_gene2861	2.81e-83	260.0	COG3829@1|root,COG3829@2|Bacteria,1N1WB@1224|Proteobacteria,42P76@68525|delta/epsilon subdivisions,2WIU6@28221|Deltaproteobacteria,2MIIW@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
k59_1149778_1	1122604.JONR01000003_gene1413	4.27e-45	152.0	COG3752@1|root,COG3752@2|Bacteria,1RD8F@1224|Proteobacteria,1S3R5@1236|Gammaproteobacteria,1XA2S@135614|Xanthomonadales	135614|Xanthomonadales	S	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
k59_1149778_2	1385515.N791_12835	2.05e-96	300.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1X39Z@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_601681_1	706587.Desti_3008	3.62e-18	91.3	COG2202@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1NU8B@1224|Proteobacteria,43D9U@68525|delta/epsilon subdivisions,2WIJG@28221|Deltaproteobacteria	2|Bacteria	KT	PFAM Bacterial regulatory protein, Fis family	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	GAF,GAF_2,HTH_8,PAS,PAS_3,PAS_4,PAS_9,STAS,Sigma54_activat,SpoIIE
k59_444644_1	1122939.ATUD01000003_gene3416	8.47e-51	171.0	COG1024@1|root,COG1024@2|Bacteria,2GKC4@201174|Actinobacteria,4CRIH@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_523395_1	1523503.JPMY01000046_gene1202	2.34e-10	60.8	COG3312@1|root,COG3312@2|Bacteria,1N777@1224|Proteobacteria,1SD0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	atp synthase	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
k59_1034943_1	443143.GM18_2300	5.63e-13	73.6	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,42RID@68525|delta/epsilon subdivisions,2WN9N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase U62 modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_326972_1	706587.Desti_0630	4.19e-20	83.6	COG1487@1|root,COG1487@2|Bacteria,1MZZ9@1224|Proteobacteria,42UZN@68525|delta/epsilon subdivisions,2WQ62@28221|Deltaproteobacteria,2MS1H@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
k59_326972_2	706587.Desti_0629	2.38e-23	90.9	COG5450@1|root,COG5450@2|Bacteria,1Q2TR@1224|Proteobacteria,42W8I@68525|delta/epsilon subdivisions,2WRTI@28221|Deltaproteobacteria,2MS5V@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
k59_1110864_1	9597.XP_003820896.1	8.74e-92	270.0	KOG4075@1|root,KOG4075@2759|Eukaryota,3A1J5@33154|Opisthokonta,3BQN7@33208|Metazoa,3D33H@33213|Bilateria,485VQ@7711|Chordata,491JI@7742|Vertebrata,3J5XN@40674|Mammalia,35AYY@314146|Euarchontoglires,4MAU3@9443|Primates,4N6BN@9604|Hominidae	33208|Metazoa	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	COX4I1	GO:0000278,GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006996,GO:0007030,GO:0007049,GO:0007275,GO:0007399,GO:0007406,GO:0007584,GO:0008150,GO:0008152,GO:0008283,GO:0008285,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0010256,GO:0010721,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022008,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0030154,GO:0031090,GO:0031667,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034641,GO:0042127,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0045595,GO:0045596,GO:0046034,GO:0046483,GO:0048519,GO:0048523,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051093,GO:0051179,GO:0051234,GO:0051239,GO:0051241,GO:0051960,GO:0051961,GO:0055085,GO:0055086,GO:0055114,GO:0060284,GO:0065007,GO:0070069,GO:0070469,GO:0071704,GO:0071840,GO:0072091,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600,GO:1902692,GO:2000026,GO:2000177,GO:2000178,GO:2000647	-	ko:K02263	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002	3.D.4.11,3.D.4.8	-	-	COX4
k59_288174_1	717785.HYPMC_4413	4.24e-120	350.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TS1Z@28211|Alphaproteobacteria,3N62H@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Cobaltochelatase CobS subunit N terminal	cobS	-	6.6.1.2	ko:K09882	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	AAA_5,CbbQ_C,CobS_N
k59_1071210_1	1121423.JONT01000002_gene2188	8.47e-50	163.0	COG1522@1|root,COG1522@2|Bacteria,1V6TK@1239|Firmicutes,24KE6@186801|Clostridia,2627S@186807|Peptococcaceae	186801|Clostridia	K	SMART Transcription regulator, AsnC-type	nirD	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
k59_1034980_1	648757.Rvan_2747	3.45e-52	179.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,3N80G@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Belongs to the peptidase M16 family	MA20_05655	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_875567_1	502025.Hoch_3156	3.66e-37	134.0	2E13Z@1|root,32WJ8@2|Bacteria,1NYI6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_719442_1	717606.PaecuDRAFT_2749	6e-45	157.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4HAW5@91061|Bacilli,26UH9@186822|Paenibacillaceae	91061|Bacilli	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_796883_1	1408823.AXUS01000001_gene634	2.67e-06	55.1	COG1113@1|root,COG1113@2|Bacteria,1VTQW@1239|Firmicutes,25EF5@186801|Clostridia,25QTQ@186804|Peptostreptococcaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
k59_288214_1	1117943.SFHH103_02318	5.26e-07	56.2	COG0810@1|root,COG0810@2|Bacteria,1RESZ@1224|Proteobacteria,2UAM6@28211|Alphaproteobacteria,4BMTN@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_1230468_1	713586.KB900536_gene2578	3.09e-19	85.5	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1WWZV@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
k59_1230468_2	1121344.JHZO01000004_gene1760	2.18e-19	90.1	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WGK8@541000|Ruminococcaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_836460_1	2340.JV46_26720	7.88e-153	445.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,1RMC3@1236|Gammaproteobacteria,1JARP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Nickel-dependent hydrogenase	hydB	-	1.12.5.1,1.12.99.6	ko:K05922,ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_679813_1	1232410.KI421425_gene1552	6.41e-60	208.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42TDV@68525|delta/epsilon subdivisions,2WP7K@28221|Deltaproteobacteria,43UHJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_209601_1	380394.Lferr_0119	3.13e-56	189.0	COG5433@1|root,COG5433@2|Bacteria,1RAHU@1224|Proteobacteria,1S1TZ@1236|Gammaproteobacteria,2NDWK@225057|Acidithiobacillales	1236|Gammaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc,DUF4338
k59_1230485_1	713587.THITH_12955	5.22e-86	263.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1WXDH@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_1035035_1	1169143.KB911035_gene2200	0.000341	42.4	COG2057@1|root,COG2057@2|Bacteria,1MWW1@1224|Proteobacteria,2VIBE@28216|Betaproteobacteria,1K086@119060|Burkholderiaceae	28216|Betaproteobacteria	I	TIGRFAM 3-oxoacid CoA-transferase, B subunit	pcaJ	-	2.8.3.6	ko:K01032	ko00362,ko01100,ko01120,map00362,map01100,map01120	-	R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_1035035_2	1121918.ARWE01000001_gene2379	6.79e-60	192.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,42QMC@68525|delta/epsilon subdivisions,2WMDH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	3-oxoacid CoA-transferase	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_1071253_1	443598.AUFA01000009_gene5816	2.8e-80	249.0	COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria,3JT2K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	MA20_20705	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
k59_1230498_1	243233.MCA0381	0.000644	42.4	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1XEP3@135618|Methylococcales	135618|Methylococcales	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
k59_1230498_2	1005048.CFU_3252	6.48e-28	117.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,473ZF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k59_995622_1	105559.Nwat_0845	7.76e-101	306.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1WVZV@135613|Chromatiales	135613|Chromatiales	P	PFAM Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_327057_1	96561.Dole_0795	1.47e-44	156.0	COG0517@1|root,COG0517@2|Bacteria,1RKZ2@1224|Proteobacteria,42SYQ@68525|delta/epsilon subdivisions,2WP9E@28221|Deltaproteobacteria,2MK65@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_1189382_1	1232410.KI421421_gene3492	1.43e-10	65.5	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria,43SU5@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_92978_1	713586.KB900536_gene2187	4.03e-111	333.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,1WWCI@135613|Chromatiales	135613|Chromatiales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
k59_1230535_1	335543.Sfum_1954	9.34e-27	108.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2WIPN@28221|Deltaproteobacteria,2MR73@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM NADH-quinone oxidoreductase, chain G	nuoG-2	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_1230535_2	335543.Sfum_1955	1.19e-33	126.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MR24@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
k59_484037_1	1123253.AUBD01000008_gene400	2.93e-48	168.0	COG3358@1|root,COG3358@2|Bacteria,1R9CT@1224|Proteobacteria,1SP2S@1236|Gammaproteobacteria,1X42J@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
k59_1192595_2	491916.RHECIAT_CH0002507	6.6e-47	152.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2U990@28211|Alphaproteobacteria,4BEPB@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_526705_1	1121937.AUHJ01000001_gene450	3.73e-90	283.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,4647F@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_722603_1	2340.JV46_16250	3.31e-42	157.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1J5FN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
k59_1234703_1	864069.MicloDRAFT_00004650	1.26e-34	129.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TRGY@28211|Alphaproteobacteria,1JZ15@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_999992_1	1122951.ATUE01000005_gene2236	2.75e-54	184.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,3NJ8X@468|Moraxellaceae	1236|Gammaproteobacteria	J	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004652,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006276,GO:0006378,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0031123,GO:0031124,GO:0034641,GO:0043170,GO:0043412,GO:0043631,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k59_1153130_1	717785.HYPMC_0047	1.19e-60	199.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TQPB@28211|Alphaproteobacteria,3N6BB@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_1039361_1	1004785.AMBLS11_17415	0.000447	43.5	COG0845@1|root,COG0845@2|Bacteria,1MV1T@1224|Proteobacteria,1RQTS@1236|Gammaproteobacteria,469SX@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
k59_1039361_2	745310.G432_08280	1.62e-37	136.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K27R@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_878993_1	1499967.BAYZ01000131_gene351	1.09e-80	249.0	COG0674@1|root,COG0674@2|Bacteria,2NNPY@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	oorA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_411611_2	574966.KB898646_gene3089	3.75e-31	114.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1XI6S@135619|Oceanospirillales	135619|Oceanospirillales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271,ko:K12961	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005,ko03036	-	-	-	SIS_2
k59_16800_1	266779.Meso_1527	1.6e-80	253.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2TQMP@28211|Alphaproteobacteria,43HDK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	synthase	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
k59_917507_1	1288298.rosmuc_02751	3.39e-29	119.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,46RMQ@74030|Roseovarius	28211|Alphaproteobacteria	V	Patched family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1000054_1	880070.Cycma_3627	2.76e-09	62.4	COG1215@1|root,COG1215@2|Bacteria,4NSR2@976|Bacteroidetes,47W1Z@768503|Cytophagia	976|Bacteroidetes	M	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
k59_1192671_1	665942.HMPREF1022_02873	2.14e-80	245.0	COG0599@1|root,COG0599@2|Bacteria,1QTZH@1224|Proteobacteria,42TJW@68525|delta/epsilon subdivisions,2X9XM@28221|Deltaproteobacteria,2M9YY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_1000067_1	338963.Pcar_3052	4.86e-76	246.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_957551_2	998674.ATTE01000001_gene459	9.86e-33	125.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,45ZW2@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_1000071_1	335543.Sfum_2793	1.95e-49	158.0	COG1144@1|root,COG1144@2|Bacteria,1N99V@1224|Proteobacteria,42V8C@68525|delta/epsilon subdivisions,2WRCP@28221|Deltaproteobacteria,2MS61@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
k59_1153192_1	314275.MADE_1009710	1.58e-85	266.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,465PG@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
k59_839823_1	394503.Ccel_2977	1.2e-83	257.0	COG2801@1|root,COG2801@2|Bacteria,1V8EJ@1239|Firmicutes,24MA4@186801|Clostridia,36HTH@31979|Clostridiaceae	186801|Clostridia	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_8,rve
k59_173920_2	1232410.KI421428_gene1003	2.57e-37	141.0	COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,42RXX@68525|delta/epsilon subdivisions,2WNME@28221|Deltaproteobacteria,43TKF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
k59_370176_1	404589.Anae109_1549	2.39e-33	132.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
k59_957587_1	305700.B447_19279	5.14e-79	247.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,2KXPJ@206389|Rhodocyclales	206389|Rhodocyclales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_411709_1	243231.GSU1731	1.42e-07	52.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NMG@68525|delta/epsilon subdivisions,2WJIS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	livG	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_411709_2	335543.Sfum_1677	1.51e-104	310.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M5A@68525|delta/epsilon subdivisions,2WK03@28221|Deltaproteobacteria,2MR93@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_957593_1	546274.EIKCOROL_00590	1.17e-15	76.6	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria,2KQI7@206351|Neisseriales	206351|Neisseriales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
k59_957593_2	96561.Dole_2783	5.36e-28	111.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2MHV9@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_291846_1	1026970.XP_008854059.1	2.17e-112	325.0	COG0231@1|root,KOG3271@2759|Eukaryota,39ZYU@33154|Opisthokonta,3BGD0@33208|Metazoa,3CUWC@33213|Bilateria,4841U@7711|Chordata,48Z7C@7742|Vertebrata,3J4FI@40674|Mammalia,359SD@314146|Euarchontoglires,4PZA0@9989|Rodentia	33208|Metazoa	J	positive regulation of translational termination	EIF5A	GO:0000003,GO:0002119,GO:0002164,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005642,GO:0005643,GO:0005737,GO:0005783,GO:0005789,GO:0005829,GO:0006403,GO:0006405,GO:0006406,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006611,GO:0006807,GO:0006810,GO:0006873,GO:0006874,GO:0006875,GO:0006886,GO:0006913,GO:0006915,GO:0007204,GO:0007275,GO:0007276,GO:0007548,GO:0007568,GO:0008104,GO:0008135,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008406,GO:0009058,GO:0009059,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0010660,GO:0010661,GO:0010662,GO:0010663,GO:0010665,GO:0010666,GO:0010941,GO:0010942,GO:0012501,GO:0012505,GO:0015031,GO:0015833,GO:0015931,GO:0016020,GO:0017069,GO:0017070,GO:0019222,GO:0019538,GO:0019725,GO:0019953,GO:0022414,GO:0030003,GO:0030425,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031503,GO:0031967,GO:0031975,GO:0031984,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032870,GO:0032991,GO:0033036,GO:0034248,GO:0034250,GO:0034613,GO:0034641,GO:0034645,GO:0035262,GO:0036477,GO:0042127,GO:0042175,GO:0042221,GO:0042592,GO:0042886,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043043,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044703,GO:0045137,GO:0045138,GO:0045184,GO:0045595,GO:0045597,GO:0045727,GO:0045901,GO:0046661,GO:0046907,GO:0047485,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048608,GO:0048609,GO:0048731,GO:0048856,GO:0048878,GO:0050657,GO:0050658,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051028,GO:0051094,GO:0051147,GO:0051149,GO:0051168,GO:0051169,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051236,GO:0051246,GO:0051247,GO:0051480,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0060255,GO:0060548,GO:0061458,GO:0065007,GO:0065008,GO:0070727,GO:0070887,GO:0071166,GO:0071310,GO:0071426,GO:0071427,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0072503,GO:0072507,GO:0080090,GO:0090598,GO:0097066,GO:0097067,GO:0097159,GO:0097447,GO:0097458,GO:0098589,GO:0098771,GO:0098805,GO:0098827,GO:0120025,GO:0120038,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000377,GO:2000379	-	ko:K03263	-	-	-	-	ko00000,ko03012	-	-	-	eIF-5a
k59_565678_1	717785.HYPMC_1407	7.04e-96	283.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria,3N643@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_173958_1	674977.VMC_19520	1.04e-88	276.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1XSD5@135623|Vibrionales	135623|Vibrionales	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_448064_1	1177154.Y5S_01704	8.29e-56	198.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_291867_1	670307.HYPDE_35628	8.91e-98	296.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2TRKY@28211|Alphaproteobacteria,3N6FW@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
k59_213164_1	1157943.KB892705_gene2123	1.04e-39	149.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,23337@1762|Mycobacteriaceae	201174|Actinobacteria	T	Histidine kinase	devS	-	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA_3
k59_1234822_1	207559.Dde_1183	1.29e-84	258.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,43B4R@68525|delta/epsilon subdivisions,2X5VN@28221|Deltaproteobacteria,2MGWB@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_411785_2	1293054.HSACCH_02358	1.51e-13	70.5	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WABU@53433|Halanaerobiales	186801|Clostridia	P	ABC transporter	-	-	3.6.3.55	ko:K15497	ko02010,map02010	M00423	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.5	-	-	ABC_tran,TOBE_2
k59_1192793_1	1410620.SHLA_75c000010	1.91e-89	278.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2TS0E@28211|Alphaproteobacteria,4BAF4@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_252562_1	90813.JQMT01000001_gene1441	1.68e-68	220.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,45ZV5@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
k59_370264_1	1232410.KI421425_gene1543	6.47e-61	202.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,42XJ0@68525|delta/epsilon subdivisions,2WT3A@28221|Deltaproteobacteria,43SUP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
k59_370276_1	631454.N177_2502	8.1e-90	274.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,1JNJQ@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_741140_2	998674.ATTE01000001_gene2818	2e-42	149.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,45ZQI@72273|Thiotrichales	72273|Thiotrichales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_818031_1	765912.Thimo_2459	4.65e-52	182.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1WW4S@135613|Chromatiales	135613|Chromatiales	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
k59_584810_1	1408303.JNJJ01000026_gene3167	2.49e-18	87.4	COG4974@1|root,COG4974@2|Bacteria,1TQXV@1239|Firmicutes,4HFGC@91061|Bacilli,1ZFQ2@1386|Bacillus	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_702093_1	998674.ATTE01000001_gene669	1.38e-11	62.4	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,46176@72273|Thiotrichales	72273|Thiotrichales	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
k59_702093_2	317025.Tcr_0815	3.98e-70	219.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,4608G@72273|Thiotrichales	72273|Thiotrichales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_35663_1	1121403.AUCV01000005_gene240	1.59e-47	156.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WQWW@28221|Deltaproteobacteria,2MPV7@213118|Desulfobacterales	28221|Deltaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
k59_152633_1	880072.Desac_1122	4.06e-43	155.0	COG1032@1|root,COG1032@2|Bacteria,1R4XI@1224|Proteobacteria,42NPM@68525|delta/epsilon subdivisions,2WJK2@28221|Deltaproteobacteria,2MQ6Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_466681_1	338966.Ppro_0890	1.55e-19	90.1	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,42Q7U@68525|delta/epsilon subdivisions,2WPC0@28221|Deltaproteobacteria,43TS6@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	ThiF family	moeB	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
k59_780494_1	885580.XP_010625865.1	7.91e-140	397.0	COG4352@1|root,KOG3295@2759|Eukaryota,39QV9@33154|Opisthokonta,3BJ7T@33208|Metazoa,3D0KP@33213|Bilateria,487X9@7711|Chordata,497PF@7742|Vertebrata,3J5WV@40674|Mammalia,35IHJ@314146|Euarchontoglires,4PXMH@9989|Rodentia	33208|Metazoa	J	ribosomal protein	RPL13	GO:0000184,GO:0000956,GO:0001889,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005783,GO:0005829,GO:0005840,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007275,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0012505,GO:0015031,GO:0015833,GO:0015934,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0022625,GO:0022626,GO:0031099,GO:0031100,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048513,GO:0048519,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051726,GO:0060255,GO:0061008,GO:0065007,GO:0070013,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:0097421,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02873	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13e
k59_466698_2	525897.Dbac_1841	2.55e-130	379.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NVJ@68525|delta/epsilon subdivisions,2WJN1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
k59_818102_1	566466.NOR53_280	1.13e-93	291.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria,1J9GA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	alkK	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
k59_1093043_1	1410625.JHWK01000005_gene1075	5.66e-18	90.9	COG0437@1|root,COG0493@1|root,COG1145@1|root,COG0437@2|Bacteria,COG0493@2|Bacteria,COG1145@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,27J4X@186928|unclassified Lachnospiraceae	186801|Clostridia	CE	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_624438_1	506534.Rhein_1765	5.88e-65	220.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,1X2RZ@135613|Chromatiales	135613|Chromatiales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_702135_1	697282.Mettu_2592	2.03e-134	391.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,1RYPY@1236|Gammaproteobacteria,1XETG@135618|Methylococcales	1236|Gammaproteobacteria	S	PFAM Transposase, IS801 IS1294	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_310725_1	349521.HCH_02825	9.45e-74	226.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S5BM@1236|Gammaproteobacteria,1XJQ6@135619|Oceanospirillales	135619|Oceanospirillales	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
k59_390401_1	1121396.KB893079_gene821	1.71e-53	189.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2WJ8V@28221|Deltaproteobacteria,2MI49@213118|Desulfobacterales	28221|Deltaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,UbiA
k59_818156_1	762376.AXYL_03845	2.78e-73	246.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,3T1EY@506|Alcaligenaceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_234842_1	177437.HRM2_27690	1.3e-08	61.2	COG4970@1|root,COG4970@2|Bacteria,1Q0DU@1224|Proteobacteria,42W7A@68525|delta/epsilon subdivisions,2WS6U@28221|Deltaproteobacteria,2MKVN@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
k59_310793_1	330084.JNYZ01000003_gene2353	8.48e-60	198.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,4DXH9@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32,HTH_33
k59_662059_1	177439.DP1279	4.19e-21	92.8	COG1418@1|root,COG1418@2|Bacteria,1RJ5H@1224|Proteobacteria,42SFF@68525|delta/epsilon subdivisions,2WP85@28221|Deltaproteobacteria,2MK90@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_980303_1	543728.Vapar_5836	6.1e-62	202.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2VHJU@28216|Betaproteobacteria,4AB94@80864|Comamonadaceae	28216|Betaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_353363_1	9606.ENSP00000228438	1.53e-111	319.0	KOG4297@1|root,KOG4297@2759|Eukaryota,3A251@33154|Opisthokonta,3BQPX@33208|Metazoa,3D8PF@33213|Bilateria,48FIG@7711|Chordata,49C6E@7742|Vertebrata,3JHC8@40674|Mammalia,35QS8@314146|Euarchontoglires,4MJXJ@9443|Primates,4MX6Q@9604|Hominidae	33208|Metazoa	TV	C-type lectin domain family 2 member B	CLEC2B	GO:0002682,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005886,GO:0005887,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0009986,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0023052,GO:0030246,GO:0031224,GO:0031226,GO:0038023,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048583,GO:0050776,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071944	-	ko:K06468,ko:K10071,ko:K10072	ko04640,ko05167,ko05169,map04640,map05167,map05169	-	-	-	ko00000,ko00001,ko04090,ko04091	-	-	-	Lectin_C
k59_275029_1	96561.Dole_0402	7.38e-78	239.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WJAM@28221|Deltaproteobacteria,2MIQY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM ABC 3 transport family	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
k59_745247_1	879212.DespoDRAFT_01333	1.41e-60	200.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_823663_1	880072.Desac_0010	3.34e-58	194.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,2MQ49@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_823663_2	96561.Dole_0514	1.06e-11	63.9	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,2MIUY@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_784406_2	1079460.ATTQ01000013_gene2669	3.07e-68	207.0	COG3436@1|root,COG3436@2|Bacteria,1RHDW@1224|Proteobacteria,2U7TH@28211|Alphaproteobacteria,4BEU4@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
k59_784406_3	114615.BRADO6932	4.52e-172	499.0	COG4372@1|root,COG4372@2|Bacteria,1MUCX@1224|Proteobacteria,2TR59@28211|Alphaproteobacteria,3JT7K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_901966_1	861299.J421_0531	1.42e-73	245.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
k59_627777_1	1128912.GMES_0437	7.84e-21	94.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1FK@1236|Gammaproteobacteria,46D7C@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
k59_627777_2	1116369.KB890024_gene555	1.19e-18	82.4	COG0454@1|root,COG0456@2|Bacteria,1RIAQ@1224|Proteobacteria,2VGWI@28211|Alphaproteobacteria,43RQE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
k59_901980_1	1122194.AUHU01000006_gene491	1.1e-30	120.0	COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,1RQQP@1236|Gammaproteobacteria,46AGJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
k59_1215438_1	56780.SYN_00295	1.45e-47	172.0	COG0366@1|root,COG3408@1|root,COG0366@2|Bacteria,COG3408@2|Bacteria,1MWBZ@1224|Proteobacteria,43AE9@68525|delta/epsilon subdivisions,2X5U3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Alpha amylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,GDE_C,GDE_N
k59_823706_1	439235.Dalk_1642	1.02e-95	304.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2MIW3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-2	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_823707_1	584708.Apau_0256	1.81e-38	145.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,3TAST@508458|Synergistetes	508458|Synergistetes	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_1137147_1	9402.XP_006906826.1	2.78e-23	95.1	2D5VE@1|root,2S55T@2759|Eukaryota,3A3W8@33154|Opisthokonta,3BRC8@33208|Metazoa,3D7PI@33213|Bilateria,48EJA@7711|Chordata,49BTJ@7742|Vertebrata,3JH5A@40674|Mammalia,4KZ3C@9397|Chiroptera	33208|Metazoa	S	Prothymosin/parathymosin family	PTMA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006325,GO:0006338,GO:0006355,GO:0006357,GO:0006996,GO:0008150,GO:0008283,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010466,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010628,GO:0010941,GO:0010951,GO:0016043,GO:0019219,GO:0019222,GO:0030154,GO:0030162,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032269,GO:0032502,GO:0034728,GO:0042393,GO:0042981,GO:0043044,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043154,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043281,GO:0043486,GO:0043933,GO:0044092,GO:0044093,GO:0044424,GO:0044464,GO:0045861,GO:0045893,GO:0045935,GO:0045944,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0051090,GO:0051091,GO:0051092,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051276,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0060548,GO:0065007,GO:0065009,GO:0071824,GO:0071840,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000116,GO:2000117,GO:2001141	-	ko:K13784	ko05169,map05169	-	-	-	ko00000,ko00001	-	-	-	Prothymosin
k59_314276_1	1121479.AUBS01000013_gene1344	1.54e-12	63.9	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,2U9GY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_314276_3	1415780.JPOG01000001_gene1540	1.07e-15	76.3	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1X45G@135614|Xanthomonadales	135614|Xanthomonadales	E	Acetolactate synthase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_196789_1	639030.JHVA01000001_gene870	3.75e-52	184.0	COG0438@1|root,COG0438@2|Bacteria,3Y68X@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_39954_1	1442599.JAAN01000005_gene951	3.24e-126	372.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1X3WE@135614|Xanthomonadales	135614|Xanthomonadales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_991_2	1122197.ATWI01000001_gene1306	1.65e-25	96.7	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,1SEIJ@1236|Gammaproteobacteria,4697E@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
k59_510177_1	1366050.N234_09800	1.11e-37	145.0	COG0222@1|root,COG0222@2|Bacteria,1RAQC@1224|Proteobacteria,2VZH9@28216|Betaproteobacteria,1KE2Z@119060|Burkholderiaceae	28216|Betaproteobacteria	J	ribosome binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_862901_1	8364.ENSXETP00000005756	7.57e-11	67.8	COG0531@1|root,KOG1287@2759|Eukaryota,39TF3@33154|Opisthokonta,3BES5@33208|Metazoa,3CZPN@33213|Bilateria,48BK4@7711|Chordata,48YDP@7742|Vertebrata	33208|Metazoa	E	Amino acid permease	-	-	-	ko:K13869	ko04216,map04216	-	-	-	ko00000,ko00001,ko02000	2.A.3.8.5	-	-	AA_permease_2
k59_275141_1	796620.VIBC2010_05709	1.28e-10	61.6	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,1XTF3@135623|Vibrionales	135623|Vibrionales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_275141_2	545276.KB898725_gene817	1.4e-31	124.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1WX0A@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_980453_1	1123261.AXDW01000001_gene1033	7.57e-79	250.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1X3ZZ@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
k59_745384_2	1114959.SZMC14600_01614	9.14e-07	54.3	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4DXBC@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_706224_1	9606.ENSP00000321259	2.32e-175	493.0	COG0176@1|root,KOG2772@2759|Eukaryota,38BFF@33154|Opisthokonta,3BD0E@33208|Metazoa,3CRJ2@33213|Bilateria,489B2@7711|Chordata,491AD@7742|Vertebrata,3J6NN@40674|Mammalia,35BUR@314146|Euarchontoglires,4MBQD@9443|Primates,4MTC6@9604|Hominidae	33208|Metazoa	H	Pfam:Transaldolase	TALDO1	GO:0003674,GO:0003824,GO:0004801,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0005997,GO:0005999,GO:0006002,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0009052,GO:0009058,GO:0009117,GO:0009987,GO:0010033,GO:0016051,GO:0016740,GO:0016744,GO:0019221,GO:0019321,GO:0019322,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0023052,GO:0030246,GO:0031974,GO:0031981,GO:0034097,GO:0034641,GO:0035722,GO:0036094,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046364,GO:0046483,GO:0046496,GO:0048029,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051186,GO:0051716,GO:0055086,GO:0065007,GO:0070013,GO:0070671,GO:0070887,GO:0071310,GO:0071345,GO:0071349,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901576	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_1058797_1	323261.Noc_2021	4.6e-43	159.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVZ7@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,Response_reg
k59_314355_1	96561.Dole_1540	7.23e-92	282.0	COG0500@1|root,COG1047@1|root,COG1047@2|Bacteria,COG2226@2|Bacteria,1PCH2@1224|Proteobacteria,42M58@68525|delta/epsilon subdivisions,2WK5Z@28221|Deltaproteobacteria,2MIYH@213118|Desulfobacterales	28221|Deltaproteobacteria	OQ	PFAM Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_745414_1	266265.Bxe_C0838	2.25e-33	126.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2VWYN@28216|Betaproteobacteria,1K8UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	Transposase_20
k59_549517_1	1157638.KB892165_gene3662	8.06e-11	67.8	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknA	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_1098058_1	713587.THITH_10785	1.57e-102	305.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1WWMZ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_1176277_1	1387312.BAUS01000002_gene456	3.03e-25	112.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria,2KMBB@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_196887_1	1499967.BAYZ01000026_gene1558	7.11e-116	352.0	COG0376@1|root,COG0376@2|Bacteria,2NQNQ@2323|unclassified Bacteria	2|Bacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_941402_1	335543.Sfum_0798	2.12e-79	251.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2MS78@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k59_1137255_1	1515746.HR45_03755	4.48e-65	212.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,2QB5A@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Amidohydrolase family	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_1137255_2	722419.PH505_at00580	6.16e-18	84.7	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,2Q20G@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	V	COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	cvaB	-	-	ko:K06147,ko:K13409	ko02010,ko04626,map02010,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39,cNMP_binding
k59_862996_1	4533.OB02G37110.1	3.56e-17	85.9	COG0265@1|root,KOG1421@2759|Eukaryota,37M01@33090|Viridiplantae,3G8IE@35493|Streptophyta,3KPK7@4447|Liliopsida,3ICN8@38820|Poales	35493|Streptophyta	O	protease do-like	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009314,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009642,GO:0009644,GO:0009892,GO:0010109,GO:0010205,GO:0016787,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0042548,GO:0043155,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043467,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1905156	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_1,PDZ_2,Trypsin_2
k59_392800_1	335543.Sfum_1869	1.44e-36	142.0	COG0784@1|root,COG4585@1|root,COG0784@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42U4X@68525|delta/epsilon subdivisions,2WQCD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_9
k59_745449_1	933262.AXAM01000030_gene797	2.78e-33	123.0	COG0289@1|root,COG0289@2|Bacteria,1QB39@1224|Proteobacteria,42NRC@68525|delta/epsilon subdivisions,2WJGM@28221|Deltaproteobacteria,2MJ2I@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the DapB family	-	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_745449_2	1121396.KB893088_gene354	3.15e-13	70.5	COG1208@1|root,COG4857@1|root,COG1208@2|Bacteria,COG4857@2|Bacteria,1R1X2@1224|Proteobacteria,43DC4@68525|delta/epsilon subdivisions,2WVQJ@28221|Deltaproteobacteria,2MPP2@213118|Desulfobacterales	28221|Deltaproteobacteria	JM	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,NTP_transferase
k59_1058839_1	31033.ENSTRUP00000046146	1.84e-230	636.0	COG5277@1|root,KOG0676@2759|Eukaryota,38C0D@33154|Opisthokonta,3BBGP@33208|Metazoa,3CRBJ@33213|Bilateria,485B3@7711|Chordata,4906G@7742|Vertebrata,49XXA@7898|Actinopterygii	33208|Metazoa	Z	Actin, alpha	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0007275,GO:0008150,GO:0009653,GO:0009887,GO:0009888,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019222,GO:0030027,GO:0030175,GO:0031252,GO:0032501,GO:0032502,GO:0042995,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044297,GO:0044424,GO:0044464,GO:0048513,GO:0048518,GO:0048729,GO:0048731,GO:0048856,GO:0050789,GO:0060255,GO:0060485,GO:0065007,GO:0072132,GO:0090130,GO:0090131,GO:0098858,GO:0120025	-	ko:K05692,ko:K10354,ko:K12313,ko:K12314	ko04015,ko04145,ko04210,ko04260,ko04261,ko04270,ko04371,ko04390,ko04391,ko04510,ko04520,ko04530,ko04611,ko04670,ko04714,ko04745,ko04810,ko04919,ko04921,ko04926,ko05100,ko05110,ko05130,ko05131,ko05132,ko05164,ko05205,ko05225,ko05410,ko05412,ko05414,ko05416,ko05418,map04015,map04145,map04210,map04260,map04261,map04270,map04371,map04390,map04391,map04510,map04520,map04530,map04611,map04670,map04714,map04745,map04810,map04919,map04921,map04926,map05100,map05110,map05130,map05131,map05132,map05164,map05205,map05225,map05410,map05412,map05414,map05416,map05418	-	-	-	ko00000,ko00001,ko03019,ko03021,ko03029,ko03036,ko04147,ko04812	-	-	-	Actin
k59_588794_1	1265505.ATUG01000002_gene1096	1.49e-103	320.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MPY1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_432046_1	1168034.FH5T_18810	5.51e-76	244.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,2FSHQ@200643|Bacteroidia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_510306_1	981384.AEYW01000013_gene700	8.12e-53	182.0	COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,2U44K@28211|Alphaproteobacteria,4ND8K@97050|Ruegeria	28211|Alphaproteobacteria	M	BCCT, betaine/carnitine/choline family transporter	-	-	-	-	-	-	-	-	-	-	-	-	BCCT
k59_588859_1	525897.Dbac_1433	1.96e-115	346.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,42M93@68525|delta/epsilon subdivisions,2WK5I@28221|Deltaproteobacteria,2M9GS@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Transposase, IS204 IS1001 IS1096 IS1165	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_1206_1	1279009.ADICEAN_01598	2.64e-82	252.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes,47URP@768503|Cytophagia	976|Bacteroidetes	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_1176388_2	1197951.I6S295_9CAUD	3.35e-19	82.0	4QCEX@10239|Viruses,4QV7Q@35237|dsDNA viruses  no RNA stage,4QU8B@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_157772_1	768066.HELO_3615	1.76e-38	142.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,1XJFS@135619|Oceanospirillales	135619|Oceanospirillales	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
k59_236197_2	870187.Thini_3190	5.63e-44	152.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,460AU@72273|Thiotrichales	72273|Thiotrichales	L	TIGRFAM A G-specific adenine glycosylase	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_510361_1	1384054.N790_10990	1.72e-58	201.0	COG1461@1|root,COG1461@2|Bacteria,1NKAM@1224|Proteobacteria,1SHAC@1236|Gammaproteobacteria,1X3IB@135614|Xanthomonadales	135614|Xanthomonadales	S	Dak2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
k59_392906_2	396588.Tgr7_1947	9.35e-16	75.5	COG3467@1|root,COG3467@2|Bacteria,1RAZD@1224|Proteobacteria,1SPF3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
k59_118659_1	1430440.MGMSRv2_2230	6.87e-42	152.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2TRPZ@28211|Alphaproteobacteria,2JQ9S@204441|Rhodospirillales	204441|Rhodospirillales	J	poly(A) polymerase	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd
k59_567348_1	443144.GM21_1027	1.65e-49	166.0	COG3637@1|root,COG3637@2|Bacteria,1RHUP@1224|Proteobacteria,42T5V@68525|delta/epsilon subdivisions,2WS5U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
k59_763028_2	382464.ABSI01000013_gene1828	5.59e-46	156.0	COG4149@1|root,COG4149@2|Bacteria,46TVT@74201|Verrucomicrobia,2IUID@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
k59_489147_1	118797.XP_007463917.1	8.57e-123	351.0	COG0522@1|root,KOG3301@2759|Eukaryota,38B77@33154|Opisthokonta,3BD6V@33208|Metazoa,3CR63@33213|Bilateria,485K5@7711|Chordata,4990N@7742|Vertebrata,3J77X@40674|Mammalia,4J4AA@91561|Cetartiodactyla	33208|Metazoa	J	ribosomal protein S9	RPS9	GO:0000184,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006417,GO:0006450,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015031,GO:0015833,GO:0015935,GO:0016070,GO:0016071,GO:0016072,GO:0019222,GO:0019439,GO:0019538,GO:0019843,GO:0022613,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032991,GO:0033036,GO:0033365,GO:0034248,GO:0034250,GO:0034470,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0042127,GO:0042254,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045182,GO:0045184,GO:0045727,GO:0045903,GO:0046483,GO:0046700,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051641,GO:0051649,GO:0060255,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0080090,GO:0090150,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904,GO:1990932,GO:2000112	-	ko:K02997	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_841577_1	1049564.TevJSym_aj00010	9.71e-22	99.4	COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,1S157@1236|Gammaproteobacteria,1JA89@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
k59_804029_1	1500257.JQNM01000006_gene1909	1.4e-29	114.0	COG2128@1|root,COG2128@2|Bacteria,1NDTM@1224|Proteobacteria,2U4SU@28211|Alphaproteobacteria,4BAV4@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_218941_1	555779.Dthio_PD3807	4.4e-22	98.6	COG2203@1|root,COG3829@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1005746_1	1121405.dsmv_0419	1.37e-82	249.0	COG1309@1|root,COG1309@2|Bacteria,1R4VA@1224|Proteobacteria,42PZX@68525|delta/epsilon subdivisions,2WK4I@28221|Deltaproteobacteria,2MI67@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_218977_1	1121451.DESAM_20317	8.88e-29	117.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1QCM5@1224|Proteobacteria,435K8@68525|delta/epsilon subdivisions,2WZYM@28221|Deltaproteobacteria,2M8S7@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,SpoIIE
k59_1005754_1	425104.Ssed_1657	1.84e-59	188.0	2DJ8V@1|root,3050U@2|Bacteria,1RE7U@1224|Proteobacteria,1SNMT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	-
k59_569898_1	1123059.KB823013_gene517	5.66e-08	49.7	COG3666@1|root,COG3666@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_100827_1	555779.Dthio_PD2653	6.57e-95	300.0	2EYTB@1|root,33S0H@2|Bacteria,1NRWZ@1224|Proteobacteria,42Y5M@68525|delta/epsilon subdivisions,2WU9Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_296395_1	1123020.AUIE01000005_gene4394	2.52e-12	68.2	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,1YF20@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Domain of unknown function (DUF3488)	tgpA	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
k59_296395_2	247633.GP2143_04805	3.43e-28	112.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,1S5F7@1236|Gammaproteobacteria,1J60U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_417517_1	1499967.BAYZ01000186_gene3977	4.08e-95	290.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6,Fer4_7,Pyr_redox_2
k59_59957_1	335543.Sfum_3356	3.49e-87	273.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria,2MQAP@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_374560_1	342610.Patl_0408	1.3e-45	159.0	COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,1SB70@1236|Gammaproteobacteria,2Q4GD@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	dcsG	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP,RimK
k59_374560_2	1265503.KB905172_gene436	1.93e-51	181.0	COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,1RPRK@1236|Gammaproteobacteria,2Q6I7@267889|Colwelliaceae	1236|Gammaproteobacteria	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	dpp4	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
k59_844210_2	1279017.AQYJ01000027_gene1772	2.4e-120	365.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,465KP@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k59_178455_1	670307.HYPDE_22753	1.35e-68	235.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2TSAE@28211|Alphaproteobacteria,3N63N@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Alpha-2-Macroglobulin	MA20_30110	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,PAN_1,Thiol-ester_cl
k59_804122_1	9541.XP_005589842.1	7.06e-123	351.0	COG1727@1|root,KOG1714@2759|Eukaryota,38CM6@33154|Opisthokonta,3BIDK@33208|Metazoa,3CTPN@33213|Bilateria,488V4@7711|Chordata,48WXM@7742|Vertebrata,3J9CH@40674|Mammalia,35GBC@314146|Euarchontoglires,4M7ZH@9443|Primates,367UQ@314294|Cercopithecoidea	33208|Metazoa	J	ribosomal protein	RPL18	GO:0000184,GO:0000956,GO:0001889,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005783,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007275,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0012505,GO:0015031,GO:0015833,GO:0015934,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0022625,GO:0022626,GO:0031099,GO:0031100,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0042788,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048513,GO:0048519,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060255,GO:0061008,GO:0065007,GO:0070013,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:0097421,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02883,ko:K21442	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04131	-	-	-	Ribosomal_L18
k59_569971_1	9606.ENSP00000421922	3.8e-117	342.0	KOG3956@1|root,KOG3956@2759|Eukaryota,38D63@33154|Opisthokonta,3BG2D@33208|Metazoa,3CT3X@33213|Bilateria,48AMZ@7711|Chordata,4976W@7742|Vertebrata,3J5IZ@40674|Mammalia,35I93@314146|Euarchontoglires,4ME4R@9443|Primates,4N1FB@9604|Hominidae	33208|Metazoa	IOTUV	Alpha-2-macroglobulin RAP, N-terminal domain	LRPAP1	GO:0001540,GO:0002090,GO:0002091,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005783,GO:0005788,GO:0005791,GO:0005793,GO:0005794,GO:0005801,GO:0005886,GO:0006810,GO:0008150,GO:0009892,GO:0009966,GO:0009968,GO:0010469,GO:0010605,GO:0010646,GO:0010648,GO:0010915,GO:0010916,GO:0010941,GO:0010984,GO:0010985,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0019899,GO:0023051,GO:0023057,GO:0030100,GO:0030545,GO:0030547,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0032091,GO:0032879,GO:0033218,GO:0035473,GO:0042277,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0044092,GO:0044422,GO:0044424,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045056,GO:0045806,GO:0048019,GO:0048237,GO:0048259,GO:0048261,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050750,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051098,GO:0051100,GO:0051128,GO:0051129,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0060255,GO:0060548,GO:0060627,GO:0065007,GO:0065009,GO:0070013,GO:0070325,GO:0070326,GO:0071944,GO:0097708,GO:0098772,GO:1900115,GO:1900116,GO:1900221,GO:1900222,GO:1900223,GO:2000272	-	ko:K22290	ko04979,map04979	-	-	-	ko00000,ko00001	-	-	-	Alpha-2-MRAP_C,Alpha-2-MRAP_N
k59_1005849_1	666685.R2APBS1_3900	8.26e-54	191.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,1X8XV@135614|Xanthomonadales	135614|Xanthomonadales	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_1078616_1	61622.XP_010358062.1	3.93e-149	433.0	COG1278@1|root,KOG3070@2759|Eukaryota,38WUV@33154|Opisthokonta,3BRDB@33208|Metazoa,3CWFW@33213|Bilateria,484CF@7711|Chordata,48X2V@7742|Vertebrata,3J9D2@40674|Mammalia,35IBP@314146|Euarchontoglires,4MM31@9443|Primates,36D3V@314294|Cercopithecoidea	33208|Metazoa	J	Cold shock protein domain	YBX1	GO:0000003,GO:0000122,GO:0000375,GO:0000377,GO:0000398,GO:0000976,GO:0000977,GO:0000978,GO:0000981,GO:0000982,GO:0000987,GO:0001012,GO:0001067,GO:0001077,GO:0001228,GO:0001701,GO:0002039,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003697,GO:0003700,GO:0003723,GO:0003729,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005681,GO:0005689,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008284,GO:0008380,GO:0009058,GO:0009059,GO:0009790,GO:0009792,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010494,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010648,GO:0010941,GO:0012505,GO:0016020,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030425,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032774,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0036477,GO:0042127,GO:0042981,GO:0042995,GO:0043005,GO:0043009,GO:0043025,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043487,GO:0043488,GO:0043489,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044703,GO:0045595,GO:0045596,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046626,GO:0046627,GO:0048255,GO:0048468,GO:0048471,GO:0048477,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051020,GO:0051093,GO:0051147,GO:0051148,GO:0051153,GO:0051154,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051252,GO:0051253,GO:0051254,GO:0051641,GO:0051704,GO:0051716,GO:0060255,GO:0060548,GO:0061013,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0070934,GO:0070937,GO:0071204,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097447,GO:0097458,GO:0097659,GO:0120025,GO:0120038,GO:0140110,GO:1900076,GO:1900077,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902369,GO:1902373,GO:1902679,GO:1902680,GO:1903311,GO:1903312,GO:1903506,GO:1903507,GO:1903508,GO:1903608,GO:1990124,GO:1990837,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K06099,ko:K09276,ko:K09277	ko04530,map04530	-	-	-	ko00000,ko00001,ko03000,ko03019,ko03041	-	-	-	CSD
k59_844233_1	1125863.JAFN01000001_gene2907	3.92e-86	273.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_374615_1	1168065.DOK_12506	8.34e-45	159.0	2DB94@1|root,2Z7UJ@2|Bacteria,1QYQJ@1224|Proteobacteria,1T3TH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
k59_687861_1	1121904.ARBP01000002_gene6986	7.71e-42	155.0	COG0446@1|root,COG0446@2|Bacteria,4PKEU@976|Bacteroidetes,47KJ9@768503|Cytophagia	976|Bacteroidetes	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
k59_883572_1	1286093.C266_05259	2.62e-23	97.4	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria,1K2KI@119060|Burkholderiaceae	28216|Betaproteobacteria	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
k59_178493_1	1294143.H681_04485	1.99e-108	322.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1157693_1	205922.Pfl01_2765	6.96e-86	265.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	insI	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k59_804174_1	1280953.HOC_19596	3.91e-113	347.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,43WH9@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	COG2217 Cation transport ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
k59_374630_1	1297569.MESS2_1080016	1.16e-45	154.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,2TT5N@28211|Alphaproteobacteria,43K44@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
k59_765742_1	2340.JV46_17330	1.36e-31	120.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1J52T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_765742_2	1123269.NX02_19875	2.72e-11	58.9	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K03589,ko:K07491	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	Y1_Tnp
k59_962248_1	743721.Psesu_2525	2.91e-14	72.8	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,1RR31@1236|Gammaproteobacteria,1X47R@135614|Xanthomonadales	135614|Xanthomonadales	S	Zn-dependent hydrolases including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_962248_2	472759.Nhal_0059	2.81e-23	92.4	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1X1FH@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_1157714_2	1168067.JAGP01000001_gene140	1.21e-33	129.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,460JS@72273|Thiotrichales	72273|Thiotrichales	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
k59_687891_1	1123279.ATUS01000001_gene2783	8.97e-07	50.4	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,1RRXT@1236|Gammaproteobacteria,1J4ZN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	COG1428 Deoxynucleoside kinases	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
k59_687891_2	502025.Hoch_2431	1.29e-23	98.2	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2YU2N@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_452468_1	439235.Dalk_4322	2.11e-52	182.0	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria,2MJDG@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
k59_491940_1	999549.KI421513_gene1928	6.71e-07	52.4	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,280JA@191028|Leisingera	28211|Alphaproteobacteria	IQ	KR domain	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_491940_2	1469613.JT55_12630	1.49e-15	77.4	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria,3FEMA@34008|Rhodovulum	28211|Alphaproteobacteria	C	Transketolase, pyrimidine binding domain	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_532570_1	740709.A10D4_07675	3.73e-12	72.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,2QFKA@267893|Idiomarinaceae	1236|Gammaproteobacteria	U	General secretion pathway	gspA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1,T2SSB
k59_921929_1	765912.Thimo_2397	2.73e-59	204.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales	135613|Chromatiales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_257184_1	1445613.JALM01000036_gene2655	1.73e-21	97.4	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4E6BZ@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_962297_1	706587.Desti_3124	8.38e-157	456.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MQ93@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
k59_374694_1	1379281.AVAG01000003_gene194	2.17e-46	162.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2M7R1@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_219236_1	1333998.M2A_3263	5.37e-104	334.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria,4BPIN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_1006001_1	933262.AXAM01000085_gene1063	4.76e-65	206.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2MI7G@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_1157771_1	748280.NH8B_0112	4.47e-77	253.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_452505_1	1179778.PMM47T1_01920	6.51e-33	126.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iSSON_1240.SSON_4131	Semialdhyde_dh,Semialdhyde_dhC
k59_727180_1	479434.Sthe_1205	2.09e-05	48.1	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi,27XPT@189775|Thermomicrobia	200795|Chloroflexi	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_727180_2	562970.Btus_0470	4.89e-24	94.7	COG2185@1|root,COG2185@2|Bacteria	2|Bacteria	I	cobalamin binding	-	-	5.4.99.13,5.4.99.2	ko:K01849,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_1240282_1	909663.KI867150_gene2871	7.77e-158	461.0	COG3039@1|root,COG3039@2|Bacteria,1QY2X@1224|Proteobacteria	1224|Proteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6
k59_257207_1	326297.Sama_2006	1.27e-35	139.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNFK@1236|Gammaproteobacteria,2QABE@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07641	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
k59_21264_1	1492922.GY26_16955	2.33e-89	285.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1J4DX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_765819_1	1121405.dsmv_0890	1.6e-93	288.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42MF0@68525|delta/epsilon subdivisions,2WMC1@28221|Deltaproteobacteria,2MIDP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase for insertion sequences IS1326 IS1353 (IS21 IS408 IS1162 family protein)	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_1240300_1	9986.ENSOCUP00000018287	8.01e-105	317.0	COG0459@1|root,KOG0357@2759|Eukaryota,38CU0@33154|Opisthokonta,3BAS6@33208|Metazoa,3CTH4@33213|Bilateria,489Y9@7711|Chordata,48VKV@7742|Vertebrata,3J8UE@40674|Mammalia,35HYQ@314146|Euarchontoglires	33208|Metazoa	O	assists the folding of proteins upon ATP hydrolysis	CCT5	GO:0000003,GO:0002199,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005832,GO:0005856,GO:0005874,GO:0006457,GO:0006458,GO:0006810,GO:0007338,GO:0007339,GO:0008037,GO:0008092,GO:0008150,GO:0009566,GO:0009605,GO:0009607,GO:0009615,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009988,GO:0010556,GO:0010557,GO:0010604,GO:0010638,GO:0015630,GO:0015631,GO:0019219,GO:0019222,GO:0019953,GO:0022414,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031647,GO:0031681,GO:0031974,GO:0031981,GO:0032204,GO:0032206,GO:0032210,GO:0032212,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033044,GO:0035036,GO:0043207,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044183,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044703,GO:0045935,GO:0048027,GO:0048487,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050821,GO:0050896,GO:0051052,GO:0051054,GO:0051082,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0060255,GO:0060341,GO:0061077,GO:0065007,GO:0065008,GO:0070013,GO:0070201,GO:0070202,GO:0070203,GO:0080090,GO:0097159,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0101031,GO:1901363,GO:1901998,GO:1903827,GO:1903829,GO:1904356,GO:1904358,GO:1904814,GO:1904816,GO:1904851,GO:1904951,GO:2000112,GO:2000278,GO:2000573,GO:2001252	-	ko:K09497	-	-	-	-	ko00000,ko03036,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_21269_1	252305.OB2597_16667	1.49e-99	301.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,2PFZ3@252301|Oceanicola	28211|Alphaproteobacteria	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_1118871_1	1366046.HIMB11_02216	4.2e-52	176.0	COG0604@1|root,COG0604@2|Bacteria,1MXRX@1224|Proteobacteria,2TRSQ@28211|Alphaproteobacteria,3ZH5K@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	C	CR COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_610007_1	1254432.SCE1572_33050	1.94e-88	283.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WKYA@28221|Deltaproteobacteria,2YU1C@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
k59_335083_1	1122603.ATVI01000005_gene3499	3.91e-18	88.2	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S1MS@1236|Gammaproteobacteria,1X9I0@135614|Xanthomonadales	135614|Xanthomonadales	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
k59_1240328_1	326427.Cagg_2835	6.62e-71	223.0	COG0596@1|root,COG0596@2|Bacteria,2G8HQ@200795|Chloroflexi,376XF@32061|Chloroflexia	32061|Chloroflexia	S	PFAM alpha beta hydrolase fold	-	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_374749_1	1286106.MPL1_08985	1.87e-80	263.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,45ZUC@72273|Thiotrichales	72273|Thiotrichales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_532685_1	765912.Thimo_2526	5.98e-129	372.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1WWM1@135613|Chromatiales	135613|Chromatiales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_296633_1	1123401.JHYQ01000024_gene1288	2.2e-57	190.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,45ZRZ@72273|Thiotrichales	72273|Thiotrichales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
k59_492043_1	335543.Sfum_0207	3.1e-59	202.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2MR8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5	nuoL-2	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
k59_1157839_1	9541.XP_005553710.1	1.69e-115	333.0	COG0105@1|root,KOG0888@2759|Eukaryota,3A1MB@33154|Opisthokonta,3BPIJ@33208|Metazoa,3D20N@33213|Bilateria,4829Y@7711|Chordata,48XS1@7742|Vertebrata,3J421@40674|Mammalia,35C6U@314146|Euarchontoglires,4MPYN@9443|Primates,35YTC@314294|Cercopithecoidea	33208|Metazoa	F	Nucleoside diphosphate kinase	NME1	GO:0000166,GO:0000287,GO:0000976,GO:0000977,GO:0001012,GO:0001067,GO:0001101,GO:0001678,GO:0001726,GO:0001882,GO:0001883,GO:0001932,GO:0001934,GO:0002682,GO:0002683,GO:0002761,GO:0002762,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0004518,GO:0004536,GO:0004550,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0006139,GO:0006165,GO:0006259,GO:0006355,GO:0006357,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0007154,GO:0007165,GO:0007166,GO:0007229,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007589,GO:0007595,GO:0008092,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008285,GO:0009117,GO:0009132,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010720,GO:0010941,GO:0010975,GO:0010976,GO:0014070,GO:0014074,GO:0014075,GO:0015630,GO:0015631,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0017076,GO:0019001,GO:0019205,GO:0019215,GO:0019219,GO:0019220,GO:0019222,GO:0019637,GO:0019725,GO:0019867,GO:0019899,GO:0019900,GO:0019901,GO:0021537,GO:0021543,GO:0021761,GO:0021766,GO:0022008,GO:0023051,GO:0023052,GO:0023056,GO:0030027,GO:0030100,GO:0030154,GO:0030334,GO:0030554,GO:0030879,GO:0030900,GO:0031090,GO:0031252,GO:0031253,GO:0031256,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032587,GO:0032879,GO:0033500,GO:0033574,GO:0033993,GO:0034284,GO:0034641,GO:0035639,GO:0035690,GO:0036094,GO:0040012,GO:0040026,GO:0040028,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042592,GO:0042593,GO:0042802,GO:0042981,GO:0042995,GO:0043015,GO:0043021,GO:0043024,GO:0043067,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043388,GO:0043408,GO:0043410,GO:0043565,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045595,GO:0045596,GO:0045597,GO:0045637,GO:0045638,GO:0045664,GO:0045666,GO:0045893,GO:0045935,GO:0045937,GO:0045944,GO:0046483,GO:0046683,GO:0046872,GO:0046903,GO:0046939,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048580,GO:0048582,GO:0048583,GO:0048584,GO:0048699,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0048878,GO:0050678,GO:0050679,GO:0050764,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050878,GO:0050896,GO:0051049,GO:0051093,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051270,GO:0051591,GO:0051716,GO:0051960,GO:0051962,GO:0055082,GO:0055086,GO:0060099,GO:0060255,GO:0060284,GO:0060322,GO:0060627,GO:0061062,GO:0061063,GO:0065007,GO:0065008,GO:0065009,GO:0070542,GO:0070887,GO:0071229,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071396,GO:0071398,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0098588,GO:0098590,GO:0098805,GO:0120025,GO:0120035,GO:0120038,GO:0140097,GO:1901074,GO:1901265,GO:1901360,GO:1901363,GO:1901654,GO:1901698,GO:1901700,GO:1901701,GO:1902105,GO:1902106,GO:1902531,GO:1902533,GO:1902680,GO:1903506,GO:1903508,GO:1903706,GO:1903707,GO:1905153,GO:1990837,GO:2000026,GO:2000112,GO:2000145,GO:2000425,GO:2001141	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
k59_1197357_1	156889.Mmc1_0737	2.04e-73	231.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2TS3D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_1240364_1	177437.HRM2_36550	6.11e-37	137.0	28MQN@1|root,2ZAZG@2|Bacteria,1MVVQ@1224|Proteobacteria,42MMM@68525|delta/epsilon subdivisions,2WKA1@28221|Deltaproteobacteria,2MHKP@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_532725_1	1379281.AVAG01000038_gene792	5.56e-56	186.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,42M9R@68525|delta/epsilon subdivisions,2WKQM@28221|Deltaproteobacteria,2M95V@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	TRAP dicarboxylate transporter, DctP subunit	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k59_688034_1	84531.JMTZ01000034_gene380	6.09e-31	116.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,1X6IY@135614|Xanthomonadales	135614|Xanthomonadales	S	ATPase or kinase	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
k59_688034_2	1328313.DS2_16214	7.4e-09	57.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,4654W@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
k59_804331_1	1198232.CYCME_1232	2.11e-65	216.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,4602T@72273|Thiotrichales	72273|Thiotrichales	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,NAD_binding_8
k59_610045_2	1510531.JQJJ01000009_gene506	2.58e-24	98.2	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2TUQM@28211|Alphaproteobacteria,3JUY9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
k59_1157868_1	570952.ATVH01000017_gene1812	0.000115	46.6	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria,2JRIA@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_101137_1	1296990.H845_1013	6.56e-89	265.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,2JSK6@204441|Rhodospirillales	204441|Rhodospirillales	L	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_922067_1	1449350.OCH239_18035	4.37e-47	167.0	COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,2TSHG@28211|Alphaproteobacteria,4KKVZ@93682|Roseivivax	28211|Alphaproteobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
k59_570211_1	1265313.HRUBRA_01216	9.25e-66	209.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1J5A0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k59_178668_1	439235.Dalk_5090	2e-66	226.0	COG1018@1|root,COG1148@1|root,COG1018@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_570216_2	1049564.TevJSym_bq00030	5.57e-18	85.5	COG1385@1|root,COG4660@1|root,COG1385@2|Bacteria,COG4660@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1J5UQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
k59_296715_1	247634.GPB2148_517	2.27e-15	75.1	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,1RYXR@1236|Gammaproteobacteria,1J77Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_296715_3	566466.NOR53_3130	2.63e-15	73.9	COG2236@1|root,COG2236@2|Bacteria,1RAZS@1224|Proteobacteria,1S2IG@1236|Gammaproteobacteria,1J8J2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
k59_1078872_2	1267005.KB911255_gene2645	1.57e-60	191.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2TRZM@28211|Alphaproteobacteria,3N6PM@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
k59_293790_1	1453501.JELR01000001_gene2391	9.4e-43	159.0	COG1629@1|root,COG1629@2|Bacteria,1MX4K@1224|Proteobacteria,1RP6B@1236|Gammaproteobacteria,464ZU@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_449838_2	765911.Thivi_4595	2.84e-36	134.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1WXB7@135613|Chromatiales	135613|Chromatiales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
k59_1116171_1	765911.Thivi_0077	2.16e-49	175.0	COG5659@1|root,COG5659@2|Bacteria,1MXSV@1224|Proteobacteria,1SBWP@1236|Gammaproteobacteria,1WZ1F@135613|Chromatiales	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
k59_414143_1	2340.JV46_12140	7.79e-16	77.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1J612@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yigA	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
k59_414143_2	1335757.SPICUR_00120	8.24e-21	91.7	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1WW4W@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_724495_1	82654.Pse7367_1525	1.24e-42	145.0	arCOG08935@1|root,32Z08@2|Bacteria,1GAUH@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_841678_1	9606.ENSP00000317780	6.05e-106	306.0	KOG4077@1|root,KOG4077@2759|Eukaryota,3A45U@33154|Opisthokonta,3BPHG@33208|Metazoa,3D79A@33213|Bilateria,483IV@7711|Chordata,495J8@7742|Vertebrata,3JB3T@40674|Mammalia,35K7K@314146|Euarchontoglires,4MGUV@9443|Primates,4N0KD@9604|Hominidae	33208|Metazoa	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	COX5A	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0042775,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902600	-	ko:K02264	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00154	-	-	ko00000,ko00001,ko00002	3.D.4.11,3.D.4.8	-	-	COX5A
k59_136155_2	1185652.USDA257_c60040	2.21e-37	132.0	COG5588@1|root,COG5588@2|Bacteria,1PZHC@1224|Proteobacteria,2TVVV@28211|Alphaproteobacteria,4BBPN@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
k59_332282_1	1123258.AQXZ01000014_gene5038	1.31e-72	240.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4FVQ3@85025|Nocardiaceae	201174|Actinobacteria	P	Heavy-metal-associated domain	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_98283_1	1242864.D187_005533	6.85e-16	84.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1R8BD@1224|Proteobacteria,43AIE@68525|delta/epsilon subdivisions,2X5YP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
k59_763147_1	1167006.UWK_00904	2.85e-21	97.8	COG0784@1|root,COG5000@1|root,COG0784@2|Bacteria,COG5000@2|Bacteria,1NC9X@1224|Proteobacteria,43BSJ@68525|delta/epsilon subdivisions,2X73B@28221|Deltaproteobacteria,2MI6A@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_880982_1	1123371.ATXH01000017_gene670	3.1e-31	125.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,2GGWQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,dCache_1
k59_1040943_2	159450.NH14_25610	3.71e-38	136.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria,1K0W9@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
k59_1076226_1	1231190.NA8A_13779	5.9e-28	102.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2UF6K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
k59_215651_1	641491.DND132_2503	6.47e-93	282.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42Q4I@68525|delta/epsilon subdivisions,2WIX3@28221|Deltaproteobacteria,2M9W3@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the interconversion of ornithine to glutamate semialdehyde	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k59_215661_1	1232437.KL661956_gene2409	1.16e-97	300.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42N1X@68525|delta/epsilon subdivisions,2WKMS@28221|Deltaproteobacteria,2MIZN@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase MttB (TMA methyltransferase)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
k59_215666_1	706587.Desti_0366	1.95e-52	175.0	COG0483@1|root,COG0483@2|Bacteria,1NVDS@1224|Proteobacteria,42ZN3@68525|delta/epsilon subdivisions,2WUWR@28221|Deltaproteobacteria,2MRNA@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_959570_1	396588.Tgr7_1289	4.44e-102	319.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1155118_1	880072.Desac_0868	2.17e-12	67.8	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,42RYV@68525|delta/epsilon subdivisions,2WNEF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_1155118_2	880072.Desac_0869	9.42e-32	120.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1116225_1	406817.XNC1_1228	5.5e-141	412.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	2-methylcitrate dehydratase	prpD	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0047547,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0072329,GO:1901575	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	iEcolC_1368.EcolC_3291	MmgE_PrpD
k59_414229_1	207954.MED92_10234	2.32e-87	283.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria,1XITZ@135619|Oceanospirillales	135619|Oceanospirillales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_724568_1	1121405.dsmv_2787	1.45e-106	327.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,2MI30@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_98345_2	314285.KT71_02952	1.1e-28	119.0	COG1680@1|root,COG4319@1|root,COG1680@2|Bacteria,COG4319@2|Bacteria,1P3SQ@1224|Proteobacteria,1S64P@1236|Gammaproteobacteria,1J7VV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF4440
k59_215702_1	706587.Desti_1464	2.95e-93	286.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,42MR9@68525|delta/epsilon subdivisions,2WIP3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
k59_801802_1	9365.XP_007528932.1	2.03e-128	370.0	COG0080@1|root,KOG0886@2759|Eukaryota,38GQE@33154|Opisthokonta,3BGZW@33208|Metazoa,3CYRC@33213|Bilateria,481V0@7711|Chordata,49365@7742|Vertebrata,3JBR2@40674|Mammalia	33208|Metazoa	J	ribosomal large subunit assembly	RPL12	GO:0000027,GO:0000381,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0015934,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048024,GO:0050684,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904	-	ko:K02870	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k59_567536_1	1502852.FG94_04151	1.07e-76	249.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,4735B@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_449920_1	713586.KB900536_gene202	2.07e-131	387.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RMWW@1236|Gammaproteobacteria,1X0DI@135613|Chromatiales	135613|Chromatiales	L	N-terminal domain of reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1,RVT_N
k59_685263_1	9606.ENSP00000306920	1.85e-117	354.0	COG1874@1|root,KOG0496@2759|Eukaryota,38D50@33154|Opisthokonta,3B96H@33208|Metazoa,3CREN@33213|Bilateria,4832W@7711|Chordata,497AD@7742|Vertebrata,3J8B5@40674|Mammalia,35GUC@314146|Euarchontoglires,4MEFW@9443|Primates,4N1IM@9604|Hominidae	33208|Metazoa	G	beta-galactosidase activity	GLB1	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0004565,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005794,GO:0005975,GO:0005996,GO:0006012,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006790,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0012505,GO:0015925,GO:0016052,GO:0016192,GO:0016787,GO:0016798,GO:0016936,GO:0016997,GO:0019318,GO:0019320,GO:0019388,GO:0030141,GO:0030203,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042339,GO:0042340,GO:0042582,GO:0042802,GO:0042803,GO:0043170,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044262,GO:0044273,GO:0044281,GO:0044282,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046365,GO:0046903,GO:0046983,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509,GO:1903510,GO:1904813	3.2.1.23	ko:K12309	ko00052,ko00511,ko00531,ko00600,ko00604,ko01100,ko04142,map00052,map00511,map00531,map00600,map00604,map01100,map04142	M00079	R01678,R03355,R04633,R06010,R07807	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	BetaGal_dom4_5,Glyco_hydro_35
k59_1116253_1	1279017.AQYJ01000026_gene57	5.51e-74	248.0	COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,1T4AK@1236|Gammaproteobacteria,46ACU@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA
k59_136233_1	1121447.JONL01000001_gene336	4.11e-54	180.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42PQA@68525|delta/epsilon subdivisions,2WNUY@28221|Deltaproteobacteria,2M887@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
k59_1237048_1	768671.ThimaDRAFT_3266	1.56e-23	100.0	COG0664@1|root,COG2066@1|root,COG0664@2|Bacteria,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,1RMY9@1236|Gammaproteobacteria,1WYNM@135613|Chromatiales	135613|Chromatiales	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
k59_685285_1	1121405.dsmv_1308	2.13e-88	264.0	COG1309@1|root,COG1309@2|Bacteria,1R7QV@1224|Proteobacteria,43AFI@68525|delta/epsilon subdivisions,2WINE@28221|Deltaproteobacteria,2MJ31@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1002678_1	153948.NAL212_2601	1.37e-57	181.0	COG1943@1|root,COG1943@2|Bacteria,1QKQ2@1224|Proteobacteria,2WC8F@28216|Betaproteobacteria,374G1@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
k59_1194733_1	1121405.dsmv_3329	2.48e-87	274.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,2MI7F@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_215761_2	317619.ANKN01000114_gene1655	7.27e-06	51.6	COG4191@1|root,COG4191@2|Bacteria,1G0AZ@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_1155189_1	314345.SPV1_05869	9.83e-77	241.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria	1224|Proteobacteria	E	o-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	iJN746.PP_2528	Cys_Met_Meta_PP
k59_528934_2	933262.AXAM01000011_gene1750	1.72e-32	119.0	COG1814@1|root,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
k59_1002709_1	595460.RRSWK_04882	1.05e-39	143.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
k59_1002709_2	1395516.PMO01_03675	1.26e-25	105.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_254580_1	9541.XP_005576572.1	2.38e-167	475.0	KOG0264@1|root,KOG0264@2759|Eukaryota,38E9H@33154|Opisthokonta,3BC0N@33208|Metazoa,3CUFN@33213|Bilateria,47ZEP@7711|Chordata,49075@7742|Vertebrata,3JB78@40674|Mammalia,35PJZ@314146|Euarchontoglires,4M6VU@9443|Primates	33208|Metazoa	B	chromatin assembly	RBBP4	GO:0000003,GO:0000118,GO:0000228,GO:0000785,GO:0000790,GO:0001558,GO:0001708,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006323,GO:0006325,GO:0006333,GO:0006338,GO:0006355,GO:0006950,GO:0006996,GO:0007275,GO:0007548,GO:0008150,GO:0008406,GO:0009266,GO:0009408,GO:0009611,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010286,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016581,GO:0017053,GO:0019219,GO:0019222,GO:0019899,GO:0022414,GO:0022607,GO:0030154,GO:0030308,GO:0031099,GO:0031101,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031497,GO:0031519,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0033186,GO:0033554,GO:0034605,GO:0034708,GO:0035097,GO:0035098,GO:0035239,GO:0035295,GO:0040007,GO:0040008,GO:0040035,GO:0042060,GO:0042246,GO:0042826,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0045137,GO:0045138,GO:0045165,GO:0045892,GO:0045926,GO:0045934,GO:0046661,GO:0048513,GO:0048519,GO:0048523,GO:0048546,GO:0048557,GO:0048562,GO:0048565,GO:0048566,GO:0048568,GO:0048589,GO:0048598,GO:0048608,GO:0048731,GO:0048806,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051276,GO:0051716,GO:0055123,GO:0060255,GO:0061458,GO:0065007,GO:0070013,GO:0070176,GO:0070370,GO:0070603,GO:0071103,GO:0071840,GO:0080090,GO:0090545,GO:0090568,GO:0090571,GO:0090598,GO:1902494,GO:1902679,GO:1903506,GO:1903507,GO:1904949,GO:1990234,GO:2000112,GO:2000113,GO:2001141	-	ko:K10752,ko:K11659	ko04218,map04218	-	-	-	ko00000,ko00001,ko03036	-	-	-	CAF1C_H4-bd,WD40
k59_1155194_1	378806.STAUR_2949	8.83e-30	122.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria,43BZA@68525|delta/epsilon subdivisions,2X7A1@28221|Deltaproteobacteria,2YU9I@29|Myxococcales	28221|Deltaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_18781_1	879212.DespoDRAFT_03498	3.16e-82	260.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2MI51@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
k59_1002720_1	1121875.KB907553_gene20	7.62e-40	144.0	COG5361@1|root,COG5361@2|Bacteria,4NKSK@976|Bacteroidetes,1IARY@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_293969_1	933262.AXAM01000013_gene1327	2.95e-69	234.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2MI13@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_293969_2	933262.AXAM01000013_gene1326	1.3e-15	71.6	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,42V1F@68525|delta/epsilon subdivisions,2WR79@28221|Deltaproteobacteria,2MKW6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
k59_1076334_1	1335757.SPICUR_06640	2.33e-115	353.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1WXQF@135613|Chromatiales	135613|Chromatiales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1002733_1	1118153.MOY_11477	8.75e-139	404.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,1RNSQ@1236|Gammaproteobacteria,1XP5E@135619|Oceanospirillales	135619|Oceanospirillales	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
k59_881110_1	9601.ENSPPYP00000005841	4.42e-160	449.0	KOG0096@1|root,KOG0096@2759|Eukaryota,38BBN@33154|Opisthokonta,3BAB7@33208|Metazoa,3CTTW@33213|Bilateria,484N9@7711|Chordata,493VE@7742|Vertebrata,3J1US@40674|Mammalia,35FAV@314146|Euarchontoglires,4MDDC@9443|Primates,4N1N2@9604|Hominidae	33208|Metazoa	U	snRNA import into nucleus	RAN	GO:0000003,GO:0000054,GO:0000055,GO:0000056,GO:0000060,GO:0000070,GO:0000132,GO:0000166,GO:0000212,GO:0000226,GO:0000278,GO:0000280,GO:0000287,GO:0000819,GO:0001654,GO:0001882,GO:0001883,GO:0003006,GO:0003407,GO:0003674,GO:0003682,GO:0003712,GO:0003713,GO:0003824,GO:0003924,GO:0005102,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005643,GO:0005654,GO:0005730,GO:0005737,GO:0005768,GO:0005814,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0005874,GO:0005876,GO:0005938,GO:0006139,GO:0006163,GO:0006259,GO:0006355,GO:0006403,GO:0006404,GO:0006405,GO:0006409,GO:0006606,GO:0006611,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007059,GO:0007154,GO:0007163,GO:0007165,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007346,GO:0007423,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009719,GO:0009725,GO:0009755,GO:0009790,GO:0009792,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010586,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0012505,GO:0014070,GO:0015031,GO:0015630,GO:0015833,GO:0015931,GO:0016032,GO:0016043,GO:0016070,GO:0016441,GO:0016458,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017038,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019058,GO:0019216,GO:0019218,GO:0019219,GO:0019222,GO:0019637,GO:0019693,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0022613,GO:0023052,GO:0030010,GO:0030154,GO:0030496,GO:0030518,GO:0030521,GO:0030522,GO:0031047,GO:0031074,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031410,GO:0031503,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0031982,GO:0032092,GO:0032501,GO:0032502,GO:0032504,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033365,GO:0033750,GO:0033993,GO:0034504,GO:0034613,GO:0034641,GO:0034660,GO:0035194,GO:0035195,GO:0035257,GO:0035258,GO:0035281,GO:0035639,GO:0036094,GO:0040001,GO:0040029,GO:0042221,GO:0042254,GO:0042278,GO:0042565,GO:0042886,GO:0043010,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043393,GO:0043401,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044464,GO:0044703,GO:0044766,GO:0045184,GO:0045540,GO:0045893,GO:0045935,GO:0046039,GO:0046128,GO:0046483,GO:0046794,GO:0046872,GO:0046890,GO:0046907,GO:0046982,GO:0046983,GO:0048285,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048545,GO:0048609,GO:0048731,GO:0048856,GO:0048869,GO:0050657,GO:0050658,GO:0050681,GO:0050789,GO:0050794,GO:0050810,GO:0050896,GO:0051030,GO:0051031,GO:0051098,GO:0051099,GO:0051168,GO:0051169,GO:0051170,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051236,GO:0051252,GO:0051254,GO:0051276,GO:0051293,GO:0051294,GO:0051321,GO:0051427,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0051704,GO:0051716,GO:0051726,GO:0055037,GO:0055086,GO:0060041,GO:0060255,GO:0061015,GO:0062012,GO:0065007,GO:0065009,GO:0070013,GO:0070727,GO:0070887,GO:0071166,GO:0071310,GO:0071383,GO:0071396,GO:0071407,GO:0071426,GO:0071428,GO:0071431,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0072521,GO:0072594,GO:0072686,GO:0075733,GO:0080090,GO:0090181,GO:0090304,GO:0097064,GO:0097159,GO:0097367,GO:0097708,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099568,GO:0106118,GO:0140014,GO:0140110,GO:1901068,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901657,GO:1902570,GO:1902579,GO:1902680,GO:1902850,GO:1902930,GO:1903046,GO:1903047,GO:1903506,GO:1903508,GO:1990498,GO:2000112,GO:2001141	-	ko:K07936	ko03008,ko03013,ko05166,ko05169,map03008,map03013,map05166,map05169	-	-	-	ko00000,ko00001,ko03009,ko03016,ko03019,ko03036,ko04031,ko04147	-	-	-	Ras
k59_293989_1	195250.CM001776_gene2416	4.11e-08	58.2	COG2716@1|root,COG2716@2|Bacteria	2|Bacteria	E	regulation of RNA biosynthetic process	-	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
k59_1041065_1	977880.RALTA_A2744	6.74e-99	305.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,1K4G7@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_529018_1	1121028.ARQE01000001_gene3068	9.45e-08	58.5	COG0697@1|root,COG0697@2|Bacteria,1MXX1@1224|Proteobacteria,2TQN0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	permeases of the drug metabolite transporter (DMT) superfamily	MA20_09090	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_763307_1	335543.Sfum_1435	1.22e-65	218.0	COG1032@1|root,COG1032@2|Bacteria,1R52J@1224|Proteobacteria,42P9G@68525|delta/epsilon subdivisions,2WKFU@28221|Deltaproteobacteria,2MRU9@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_1237171_1	1005048.CFU_1187	3.58e-44	154.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI0K@28216|Betaproteobacteria,473K3@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_215885_1	76114.p2A13	9.65e-104	320.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2VIEB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
k59_414439_1	717785.HYPMC_0965	2.77e-97	309.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,3N6CN@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_881166_1	1504672.669785375	1.88e-10	62.8	COG3713@1|root,COG3713@2|Bacteria,1MWQN@1224|Proteobacteria,2VX3J@28216|Betaproteobacteria	28216|Betaproteobacteria	M	MltA-interacting protein MipA	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	MipA
k59_1155285_1	1120953.AUBH01000007_gene1877	1.5e-102	316.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,464DA@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Peptidase, M13	pepO	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
k59_489478_1	1217718.ALOU01000071_gene5076	3.33e-19	89.4	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,1K2GD@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
k59_648239_1	52598.EE36_06608	1.28e-21	98.6	COG0687@1|root,COG0687@2|Bacteria,1MU0I@1224|Proteobacteria,2TRJ3@28211|Alphaproteobacteria,3ZV3Z@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
k59_1240500_1	366602.Caul_4395	1.98e-12	63.5	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,2KGMX@204458|Caulobacterales	204458|Caulobacterales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
k59_1240500_2	1453501.JELR01000001_gene2616	8.65e-13	70.9	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,467Q6@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	yafS	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_648246_1	856793.MICA_784	7.05e-55	186.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,4BPX1@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM pfkB family carbohydrate kinase	pfkB	-	2.7.1.20,2.7.1.4	ko:K00847,ko:K00856	ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100	-	R00185,R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_648246_2	666509.RCA23_c01310	1.03e-13	73.2	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	belongs to the aldehyde dehydrogenase family	aldA	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_296767_1	1122918.KB907247_gene4736	4.23e-12	68.6	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,26R5Q@186822|Paenibacillaceae	91061|Bacilli	P	Potassium uptake system protein	ktrA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_296767_2	335543.Sfum_0406	3.01e-05	45.8	COG0607@1|root,COG1633@1|root,COG0607@2|Bacteria,COG1633@2|Bacteria,1MZPW@1224|Proteobacteria,42NX5@68525|delta/epsilon subdivisions,2WMJ4@28221|Deltaproteobacteria,2MRIH@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rubrerythrin
k59_296771_1	926550.CLDAP_27060	4.67e-48	172.0	COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_20,fn3
k59_532894_1	1387312.BAUS01000002_gene511	1.52e-37	142.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,2KKB0@206350|Nitrosomonadales	206350|Nitrosomonadales	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_219532_1	1177181.T9A_01163	8.05e-118	358.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1XHQB@135619|Oceanospirillales	135619|Oceanospirillales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	-	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_727393_1	644282.Deba_2226	5.72e-75	251.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_648273_1	566466.NOR53_398	4.67e-45	165.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVS@1236|Gammaproteobacteria,1J55S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA
k59_219557_1	933262.AXAM01000011_gene1751	4.81e-93	291.0	COG0205@1|root,COG0205@2|Bacteria,1R560@1224|Proteobacteria,42P6N@68525|delta/epsilon subdivisions,2WINA@28221|Deltaproteobacteria,2MHN0@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Phosphofructokinase	pfp	-	2.7.1.11,2.7.1.90	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k59_1078952_1	1121405.dsmv_2208	5.97e-43	153.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2MHZW@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_219565_1	1008457.BAEX01000048_gene737	3.26e-35	138.0	COG1506@1|root,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,1HXW2@117743|Flavobacteriia,47HFG@76831|Myroides	976|Bacteroidetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
k59_1043345_1	1089550.ATTH01000001_gene2440	6.6e-105	320.0	COG1053@1|root,COG1053@2|Bacteria,4NHXK@976|Bacteroidetes,1FJ4E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_60349_1	530564.Psta_1034	1.33e-35	130.0	COG2085@1|root,COG2085@2|Bacteria,2J3GA@203682|Planctomycetes	203682|Planctomycetes	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
k59_138951_1	1415778.JQMM01000001_gene1070	1.08e-59	194.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,1RP15@1236|Gammaproteobacteria,1J4Q4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
k59_688204_1	1280673.AUJJ01000040_gene11	1.04e-18	86.7	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,4BXRC@830|Butyrivibrio	186801|Clostridia	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_962594_1	9606.ENSP00000337623	1.08e-116	339.0	KOG4705@1|root,KOG4705@2759|Eukaryota,39TCX@33154|Opisthokonta,3BFY2@33208|Metazoa,3CZPB@33213|Bilateria,488EV@7711|Chordata,48ZI8@7742|Vertebrata,3J6YT@40674|Mammalia,35P9Q@314146|Euarchontoglires,4M96I@9443|Primates,4MZT7@9604|Hominidae	33208|Metazoa	S	Ydr279p protein family (RNase H2 complex component)	RNASEH2B	GO:0001701,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006139,GO:0006401,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007346,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009057,GO:0009117,GO:0009259,GO:0009790,GO:0009792,GO:0009892,GO:0009987,GO:0010389,GO:0010468,GO:0010564,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019222,GO:0019439,GO:0019637,GO:0019693,GO:0031974,GO:0031981,GO:0032299,GO:0032501,GO:0032502,GO:0032991,GO:0034641,GO:0034655,GO:0042127,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0046700,GO:0048145,GO:0048146,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048856,GO:0050789,GO:0050794,GO:0051726,GO:0055086,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901135,GO:1901360,GO:1901361,GO:1901575,GO:1901976,GO:1901987,GO:1901990,GO:1902749,GO:2000001,GO:2001020	-	ko:K10744	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	RNase_H2-Ydr279
k59_391522_2	1127673.GLIP_2655	3.01e-15	79.0	COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1MVUT@1224|Proteobacteria,1RQB3@1236|Gammaproteobacteria,465BQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	chorismate mutase	tyrA	GO:0000166,GO:0003674,GO:0003824,GO:0004106,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	1.3.1.12,5.4.99.5	ko:K04517,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R01715,R01728	RC00125,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_2925	ACT,CM_2,PDH
k59_273149_1	1121405.dsmv_3570	4.76e-112	334.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2WIZ7@28221|Deltaproteobacteria,2MHM9@213118|Desulfobacterales	28221|Deltaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
k59_351250_1	743299.Acife_1072	2.3e-72	234.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,2NBYN@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_625710_1	500635.MITSMUL_05001	1.64e-15	80.5	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4H39X@909932|Negativicutes	909932|Negativicutes	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
k59_351324_1	1121405.dsmv_2935	6.76e-116	342.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,42Q6T@68525|delta/epsilon subdivisions,2WJ4M@28221|Deltaproteobacteria,2MIVF@213118|Desulfobacterales	28221|Deltaproteobacteria	E	HMGL-like	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like
k59_75409_1	933262.AXAM01000039_gene1153	2.18e-132	391.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2MI5B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_75412_1	27679.XP_003937912.1	4.71e-118	341.0	KOG1904@1|root,KOG1904@2759|Eukaryota,38GK1@33154|Opisthokonta,3BMF9@33208|Metazoa,3CRVW@33213|Bilateria,485N5@7711|Chordata,494YY@7742|Vertebrata,3JC85@40674|Mammalia,35NN7@314146|Euarchontoglires,4M7U8@9443|Primates	33208|Metazoa	K	Hepatoma-derived growth factor	HDGF	GO:0000122,GO:0000976,GO:0000977,GO:0000978,GO:0000981,GO:0000982,GO:0000987,GO:0001012,GO:0001067,GO:0001078,GO:0001221,GO:0001222,GO:0001227,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003712,GO:0003714,GO:0005102,GO:0005488,GO:0005515,GO:0005539,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006355,GO:0006357,GO:0006950,GO:0006986,GO:0007154,GO:0007165,GO:0008083,GO:0008104,GO:0008134,GO:0008150,GO:0008201,GO:0008283,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010468,GO:0010469,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0017053,GO:0019219,GO:0019222,GO:0023051,GO:0023052,GO:0030545,GO:0030968,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032991,GO:0033036,GO:0033365,GO:0033554,GO:0034504,GO:0034613,GO:0034620,GO:0034976,GO:0035966,GO:0035967,GO:0036498,GO:0042221,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043565,GO:0044212,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0048018,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051252,GO:0051253,GO:0051254,GO:0051641,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070013,GO:0070727,GO:0070887,GO:0071310,GO:0080090,GO:0097159,GO:0097367,GO:0098772,GO:0140110,GO:1901363,GO:1901681,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K16641	-	-	-	-	ko00000,ko00536	-	-	-	PWWP
k59_311985_1	1123376.AUIU01000014_gene552	2.17e-56	193.0	COG0296@1|root,COG0296@2|Bacteria,3J0WY@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_625784_1	269796.Rru_A1765	9.57e-23	92.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,2JT97@204441|Rhodospirillales	204441|Rhodospirillales	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
k59_625784_2	870187.Thini_4364	1.24e-32	122.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,45ZSJ@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
k59_507694_1	1144305.PMI02_00630	2.83e-08	58.2	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TVB1@28211|Alphaproteobacteria,2K343@204457|Sphingomonadales	204457|Sphingomonadales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
k59_75462_1	1265505.ATUG01000002_gene1615	2.39e-60	207.0	COG0247@1|root,COG1150@1|root,COG0247@2|Bacteria,COG1150@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria,2MJHX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_507697_1	96561.Dole_2133	1.48e-84	263.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2MIA5@213118|Desulfobacterales	28221|Deltaproteobacteria	L	AAA ATPase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_979111_1	1123392.AQWL01000007_gene1007	5.13e-53	184.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,1KRY7@119069|Hydrogenophilales	119069|Hydrogenophilales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
k59_1174162_1	349521.HCH_03409	5.49e-27	112.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1XI30@135619|Oceanospirillales	1236|Gammaproteobacteria	I	Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate	yfcX	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_1174162_2	159087.Daro_1545	8.07e-19	85.1	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VMHS@28216|Betaproteobacteria,2KUQ2@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the thiolase family	fadA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_781877_1	1437824.BN940_02361	3.82e-21	90.1	2CB7M@1|root,31H4T@2|Bacteria,1MYWT@1224|Proteobacteria,2VSTJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_36945_1	1121456.ATVA01000014_gene561	4.94e-60	198.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42SS8@68525|delta/epsilon subdivisions,2WPMH@28221|Deltaproteobacteria,2MAUU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_979138_1	335543.Sfum_3643	1.44e-108	326.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria,2MQBU@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
k59_819578_1	391615.ABSJ01000054_gene1379	2.12e-57	198.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1J5BG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_819578_2	396588.Tgr7_3049	3.19e-05	43.1	COG5481@1|root,COG5481@2|Bacteria	2|Bacteria	S	small protein containing a coiled-coil domain	MA20_03740	-	-	-	-	-	-	-	-	-	-	-	DUF465
k59_859936_1	9541.XP_005584433.1	4.37e-121	355.0	COG0652@1|root,KOG0865@2759|Eukaryota	2759|Eukaryota	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K03767,ko:K09565,ko:K16663	ko01503,ko04020,ko04022,ko04217,ko05012,ko05016,ko05145,map01503,map04020,map04022,map04217,map05012,map05016,map05145	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147,ko04516	-	-	-	Pro_isomerase
k59_819582_1	379066.GAU_0192	2.08e-18	85.1	COG0075@1|root,COG0075@2|Bacteria,1ZTF3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_819582_2	1173025.GEI7407_0489	5.71e-26	104.0	COG1335@1|root,COG1335@2|Bacteria,1G10P@1117|Cyanobacteria,1H8R3@1150|Oscillatoriales	1117|Cyanobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_742735_1	1123279.ATUS01000006_gene3374	5.57e-38	132.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1J6NZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_1057364_1	187272.Mlg_0413	3.36e-58	195.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1WWPA@135613|Chromatiales	135613|Chromatiales	S	modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_781952_1	649747.HMPREF0083_01980	2.8e-33	127.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,4HD95@91061|Bacilli,26THC@186822|Paenibacillaceae	91061|Bacilli	EK	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
k59_899891_1	1280947.HY30_17285	4.73e-35	126.0	2CVK5@1|root,32SXS@2|Bacteria,1N0ZG@1224|Proteobacteria,2UCR3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_819611_1	73501.XP_006672306.1	5.16e-18	82.8	2CXM7@1|root,2RYCS@2759|Eukaryota,39M19@33154|Opisthokonta,3NZXA@4751|Fungi,3QK26@4890|Ascomycota,212EM@147550|Sordariomycetes,3TDUK@5125|Hypocreales	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_391794_1	318161.Sden_3360	4.05e-50	169.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,2Q9Q5@267890|Shewanellaceae	1236|Gammaproteobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_625945_1	1499967.BAYZ01000171_gene5607	2.17e-09	58.9	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_154076_1	504832.OCAR_7523	5.62e-29	118.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TT1G@28211|Alphaproteobacteria,3JQQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_742764_1	1267005.KB911259_gene3872	9.92e-33	119.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,3N70J@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_819638_1	9606.ENSP00000253024	1.64e-231	657.0	KOG2177@1|root,KOG2177@2759|Eukaryota,38F8A@33154|Opisthokonta,3BD9C@33208|Metazoa,3CRZC@33213|Bilateria,486MZ@7711|Chordata,494SK@7742|Vertebrata,3J4B3@40674|Mammalia,35G0C@314146|Euarchontoglires,4MIE8@9443|Primates,4MSUG@9604|Hominidae	33208|Metazoa	K	B-Box C-terminal domain	TRIM28	GO:0000003,GO:0000122,GO:0000228,GO:0000785,GO:0000790,GO:0000791,GO:0000792,GO:0001701,GO:0001837,GO:0001890,GO:0001892,GO:0002009,GO:0002376,GO:0003006,GO:0003401,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003712,GO:0003713,GO:0003714,GO:0003824,GO:0004672,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005667,GO:0005694,GO:0005719,GO:0005720,GO:0006139,GO:0006259,GO:0006281,GO:0006282,GO:0006304,GO:0006305,GO:0006306,GO:0006351,GO:0006352,GO:0006355,GO:0006357,GO:0006366,GO:0006367,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0006974,GO:0007154,GO:0007165,GO:0007264,GO:0007265,GO:0007275,GO:0007565,GO:0007566,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0016043,GO:0016070,GO:0016301,GO:0016310,GO:0016567,GO:0016740,GO:0016772,GO:0016773,GO:0016925,GO:0018130,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019787,GO:0019899,GO:0019904,GO:0022414,GO:0022607,GO:0023052,GO:0030154,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031625,GO:0031935,GO:0031937,GO:0031974,GO:0031981,GO:0032259,GO:0032386,GO:0032388,GO:0032446,GO:0032501,GO:0032502,GO:0032774,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033044,GO:0033157,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0035851,GO:0036211,GO:0040007,GO:0040012,GO:0040013,GO:0042306,GO:0042307,GO:0043009,GO:0043045,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043388,GO:0043412,GO:0043414,GO:0043900,GO:0043901,GO:0043903,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044389,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044703,GO:0044706,GO:0044728,GO:0044798,GO:0045069,GO:0045071,GO:0045087,GO:0045091,GO:0045739,GO:0045869,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046777,GO:0046822,GO:0046824,GO:0046872,GO:0046914,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048525,GO:0048568,GO:0048583,GO:0048584,GO:0048589,GO:0048598,GO:0048608,GO:0048729,GO:0048731,GO:0048762,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051052,GO:0051053,GO:0051054,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051222,GO:0051223,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0051704,GO:0051716,GO:0060026,GO:0060028,GO:0060255,GO:0060341,GO:0060429,GO:0060485,GO:0060560,GO:0060669,GO:0060968,GO:0061458,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070087,GO:0070201,GO:0070647,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090304,GO:0090308,GO:0090309,GO:0090316,GO:0090575,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1900180,GO:1900182,GO:1901360,GO:1901362,GO:1901363,GO:1901535,GO:1901536,GO:1901538,GO:1901564,GO:1901576,GO:1902186,GO:1902187,GO:1902275,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1903827,GO:1903829,GO:1903900,GO:1903901,GO:1904589,GO:1904591,GO:1904951,GO:1905269,GO:1990841,GO:2000112,GO:2000113,GO:2000653,GO:2001020,GO:2001022,GO:2001141,GO:2001252	2.3.2.27	ko:K08882,ko:K08883	-	-	-	-	ko00000,ko01000,ko01001,ko04121	-	-	-	PHD,zf-B_box,zf-RING_5
k59_819639_1	421052.F945_02565	5.46e-07	50.8	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,3NIYC@468|Moraxellaceae	1236|Gammaproteobacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008412,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iZ_1308.Z5639	UbiA
k59_819639_2	663932.KB902575_gene851	5.55e-62	202.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2TQQP@28211|Alphaproteobacteria,2JPSN@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
k59_37051_1	1297570.MESS4_670041	1e-72	239.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2U4DT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_663455_1	1318628.MARLIPOL_15342	1e-21	91.3	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,466HT@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212	Ham1p_like
k59_663455_2	1121116.KB894770_gene1152	1.07e-23	99.8	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,4AAMV@80864|Comamonadaceae	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_1094681_1	444860.E3SJG0_9CAUD	1.74e-61	196.0	4QCHF@10239|Viruses,4QW57@35237|dsDNA viruses  no RNA stage,4QPIH@28883|Caudovirales,4QHVS@10662|Myoviridae	10662|Myoviridae	S	PhoH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1094681_2	268746.Q58N04_BPPRM	5.9e-18	80.5	4QHG7@10239|Viruses,4R0G1@35237|dsDNA viruses  no RNA stage,4QRS2@28883|Caudovirales,4QJ56@10662|Myoviridae	10662|Myoviridae	S	exonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_193119_1	81985.XP_006279602.1	1.37e-96	301.0	COG1012@1|root,KOG2451@2759|Eukaryota,37KPW@33090|Viridiplantae,3GA3J@35493|Streptophyta,3HMPB@3699|Brassicales	35493|Streptophyta	C	Delta-1-pyrroline-5-carboxylate dehydrogenase 12A1	-	GO:0003674,GO:0003824,GO:0003842,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006536,GO:0006560,GO:0006562,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009507,GO:0009536,GO:0009628,GO:0009651,GO:0009987,GO:0010133,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019752,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0055114,GO:0071704,GO:0072593,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
k59_1057446_1	335543.Sfum_0294	2.51e-52	186.0	COG0591@1|root,COG1842@1|root,COG3852@1|root,COG0591@2|Bacteria,COG1842@2|Bacteria,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43CEX@68525|delta/epsilon subdivisions,2X7PW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,PAS
k59_75624_1	566466.NOR53_1604	8.58e-58	190.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,1RN1A@1236|Gammaproteobacteria,1J7HT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_42066_1	981336.F944_01474	5.37e-29	117.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,3NIEI@468|Moraxellaceae	1236|Gammaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
k59_42066_2	270374.MELB17_02605	2.1e-36	135.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,464RG@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_0056	PdxA
k59_551608_3	880072.Desac_1934	3.58e-24	94.7	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,42W2F@68525|delta/epsilon subdivisions,2WRUM@28221|Deltaproteobacteria,2MS8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	hup-1	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_669119_1	517722.AEUE01000007_gene327	1.94e-40	146.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,2K0RE@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K13581	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_825880_1	1121091.AUMP01000002_gene2140	1.62e-28	116.0	COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli	91061|Bacilli	BQ	histone deacetylase	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	iYO844.BSU29710	Hist_deacetyl
k59_982807_1	1265505.ATUG01000002_gene1746	5.48e-81	252.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_904116_1	1116472.MGMO_83c00160	4.94e-192	548.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XESH@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_512639_1	1121013.P873_13880	1.76e-15	72.4	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,1X5Z8@135614|Xanthomonadales	135614|Xanthomonadales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
k59_512639_2	395019.Bmul_0435	2.24e-46	166.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,1K45G@119060|Burkholderiaceae	28216|Betaproteobacteria	O	magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_159704_1	519989.ECTPHS_07586	4.08e-79	256.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_551635_1	9606.ENSP00000346550	6.83e-223	629.0	KOG0819@1|root,KOG0819@2759|Eukaryota,38FEE@33154|Opisthokonta,3BCMH@33208|Metazoa,3CXS1@33213|Bilateria,486J4@7711|Chordata,494WX@7742|Vertebrata,3J803@40674|Mammalia,359XB@314146|Euarchontoglires,4M5VZ@9443|Primates,4N23G@9604|Hominidae	33208|Metazoa	U	Annexin repeats	ANXA6	GO:0000166,GO:0000323,GO:0000910,GO:0001501,GO:0001667,GO:0001725,GO:0001755,GO:0001786,GO:0001882,GO:0001883,GO:0002062,GO:0003413,GO:0003416,GO:0003417,GO:0003418,GO:0003674,GO:0003779,GO:0005215,GO:0005216,GO:0005261,GO:0005262,GO:0005488,GO:0005496,GO:0005515,GO:0005525,GO:0005539,GO:0005543,GO:0005544,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005764,GO:0005765,GO:0005766,GO:0005768,GO:0005770,GO:0005773,GO:0005774,GO:0005819,GO:0005829,GO:0005856,GO:0005886,GO:0005911,GO:0005912,GO:0005924,GO:0005925,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006897,GO:0006909,GO:0006915,GO:0006928,GO:0006937,GO:0007049,GO:0007154,GO:0007165,GO:0007275,GO:0008092,GO:0008150,GO:0008201,GO:0008219,GO:0008289,GO:0008324,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010008,GO:0010035,GO:0010038,GO:0012501,GO:0012505,GO:0012506,GO:0014031,GO:0014032,GO:0014033,GO:0014704,GO:0015075,GO:0015085,GO:0015267,GO:0015276,GO:0015318,GO:0015485,GO:0015629,GO:0015630,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0016324,GO:0016477,GO:0017076,GO:0019001,GO:0019725,GO:0019866,GO:0019899,GO:0022402,GO:0022607,GO:0022803,GO:0022834,GO:0022836,GO:0022838,GO:0022839,GO:0022857,GO:0022890,GO:0023052,GO:0030001,GO:0030003,GO:0030054,GO:0030055,GO:0030061,GO:0030139,GO:0030141,GO:0030154,GO:0030496,GO:0030659,GO:0030667,GO:0031090,GO:0031214,GO:0031224,GO:0031410,GO:0031902,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0031982,GO:0032432,GO:0032501,GO:0032502,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032879,GO:0032934,GO:0032991,GO:0034220,GO:0034702,GO:0034703,GO:0034704,GO:0035265,GO:0035374,GO:0035639,GO:0036094,GO:0038023,GO:0040007,GO:0040011,GO:0042221,GO:0042383,GO:0042470,GO:0042581,GO:0042582,GO:0042583,GO:0042584,GO:0042592,GO:0042641,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043178,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044057,GO:0044085,GO:0044291,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044430,GO:0044433,GO:0044437,GO:0044440,GO:0044444,GO:0044446,GO:0044455,GO:0044459,GO:0044464,GO:0044548,GO:0044877,GO:0045177,GO:0045335,GO:0046873,GO:0046903,GO:0046983,GO:0048306,GO:0048468,GO:0048471,GO:0048513,GO:0048519,GO:0048523,GO:0048589,GO:0048705,GO:0048731,GO:0048762,GO:0048770,GO:0048856,GO:0048863,GO:0048864,GO:0048869,GO:0048870,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051015,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051259,GO:0051260,GO:0051282,GO:0051283,GO:0051301,GO:0051560,GO:0051592,GO:0051674,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0060089,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060485,GO:0061448,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070161,GO:0070509,GO:0070588,GO:0070838,GO:0071840,GO:0071944,GO:0072341,GO:0072503,GO:0072507,GO:0072511,GO:0090257,GO:0097159,GO:0097190,GO:0097367,GO:0097517,GO:0097708,GO:0098588,GO:0098590,GO:0098655,GO:0098657,GO:0098660,GO:0098662,GO:0098771,GO:0098796,GO:0098805,GO:0098852,GO:0098868,GO:0099503,GO:1901265,GO:1901363,GO:1901681,GO:1902495,GO:1990351	-	ko:K17094,ko:K17095	-	-	-	-	ko00000,ko04131,ko04147	1.A.31.1.1,1.A.31.1.2,1.A.31.1.6	-	-	Annexin
k59_629938_1	1121456.ATVA01000011_gene1357	7.55e-83	273.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WJKV@28221|Deltaproteobacteria,2M7VM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_1217495_1	9606.ENSP00000385385	1.26e-206	579.0	COG0526@1|root,KOG0191@2759|Eukaryota,38DXF@33154|Opisthokonta,3BBEW@33208|Metazoa,3CSZI@33213|Bilateria,48155@7711|Chordata,48Z1C@7742|Vertebrata,3JAXT@40674|Mammalia,35F0X@314146|Euarchontoglires,4MIJ3@9443|Primates,4MSE5@9604|Hominidae	33208|Metazoa	O	protein disulfide isomerase activity	PDIA6	GO:0001775,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005789,GO:0005790,GO:0005793,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006807,GO:0006810,GO:0006897,GO:0006909,GO:0006950,GO:0006986,GO:0007154,GO:0007155,GO:0007165,GO:0007596,GO:0007599,GO:0008150,GO:0008152,GO:0009611,GO:0009987,GO:0010033,GO:0012505,GO:0015036,GO:0015037,GO:0016020,GO:0016192,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022610,GO:0023052,GO:0030100,GO:0030168,GO:0030968,GO:0031410,GO:0031974,GO:0031982,GO:0031984,GO:0032501,GO:0032879,GO:0032991,GO:0033554,GO:0034109,GO:0034620,GO:0034663,GO:0034976,GO:0035966,GO:0035967,GO:0036211,GO:0036498,GO:0042060,GO:0042175,GO:0042221,GO:0042470,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043277,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045807,GO:0046872,GO:0048518,GO:0048522,GO:0048770,GO:0050764,GO:0050766,GO:0050789,GO:0050794,GO:0050817,GO:0050878,GO:0050896,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051716,GO:0055114,GO:0060627,GO:0065007,GO:0065008,GO:0070013,GO:0070527,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0097708,GO:0098609,GO:0098657,GO:0098827,GO:0140096,GO:1901564,GO:2000425,GO:2000427	5.3.4.1	ko:K09584	ko04141,map04141	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04131	-	-	-	Thioredoxin
k59_786726_1	1122201.AUAZ01000020_gene2739	5.05e-36	135.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,465UK@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_316358_1	9606.ENSP00000307786	7.88e-73	218.0	COG3474@1|root,KOG3453@2759|Eukaryota,3A3GP@33154|Opisthokonta,3BRIC@33208|Metazoa,3D83X@33213|Bilateria,48EM9@7711|Chordata,49BMX@7742|Vertebrata,3JGYD@40674|Mammalia,35SDW@314146|Euarchontoglires,4MS0W@9443|Primates,4N6YT@9604|Hominidae	33208|Metazoa	C	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity	CYCS	GO:0000003,GO:0000159,GO:0003006,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005758,GO:0005829,GO:0006091,GO:0006119,GO:0006122,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006919,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007291,GO:0007349,GO:0008150,GO:0008152,GO:0008219,GO:0008287,GO:0008635,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009653,GO:0009893,GO:0009987,GO:0010604,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0017144,GO:0019222,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0019953,GO:0020037,GO:0022412,GO:0022414,GO:0022603,GO:0022900,GO:0022904,GO:0023052,GO:0030154,GO:0030162,GO:0031090,GO:0031323,GO:0031325,GO:0031966,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033554,GO:0034599,GO:0034641,GO:0035556,GO:0042221,GO:0042773,GO:0042775,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043280,GO:0043281,GO:0044093,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045155,GO:0045333,GO:0045595,GO:0045862,GO:0046034,GO:0046483,GO:0046668,GO:0046669,GO:0046906,GO:0048037,GO:0048232,GO:0048468,GO:0048515,GO:0048518,GO:0048522,GO:0048609,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051239,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051704,GO:0051716,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0060284,GO:0065007,GO:0065009,GO:0070013,GO:0070469,GO:0070887,GO:0071704,GO:0071840,GO:0072521,GO:0080090,GO:0097159,GO:0097190,GO:0097193,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902494,GO:1903293,GO:2000026,GO:2000027,GO:2000116,GO:2001056	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
k59_708151_2	1220582.RRU01S_27_00610	2.65e-12	72.4	COG0845@1|root,COG0845@2|Bacteria,1R3R4@1224|Proteobacteria,2U45N@28211|Alphaproteobacteria,4BFWV@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K13408	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
k59_198994_1	384765.SIAM614_07253	1.29e-19	86.7	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
k59_198994_2	997296.PB1_12134	1.91e-19	82.4	COG2076@1|root,COG2076@2|Bacteria,1VEUF@1239|Firmicutes,4HNA6@91061|Bacilli,1ZQJN@1386|Bacillus	91061|Bacilli	U	Small Multidrug Resistance protein	-	-	-	ko:K03297	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
k59_42141_1	62928.azo1676	5.67e-110	325.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VINV@28216|Betaproteobacteria,2KU6E@206389|Rhodocyclales	206389|Rhodocyclales	C	Radical SAM superfamily	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_238078_1	296591.Bpro_4334	6.63e-93	283.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2VI0E@28216|Betaproteobacteria,4ABVU@80864|Comamonadaceae	28216|Betaproteobacteria	L	Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k59_81673_1	1123229.AUBC01000013_gene2594	1.21e-102	317.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,3JRC4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_42173_1	1392838.AWNM01000097_gene151	2.59e-07	57.0	COG2863@1|root,COG2863@2|Bacteria,1RGTS@1224|Proteobacteria,2VSFZ@28216|Betaproteobacteria,3T42M@506|Alcaligenaceae	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_591003_1	1094980.Mpsy_3025	1.99e-05	48.1	COG0438@1|root,arCOG01403@2157|Archaea,2XZYD@28890|Euryarchaeota,2NAIR@224756|Methanomicrobia	224756|Methanomicrobia	M	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,MannoseP_isomer
k59_591003_2	643648.Slip_0761	1.17e-30	120.0	COG3934@1|root,COG3934@2|Bacteria,1UEWM@1239|Firmicutes,24AQC@186801|Clostridia,42KI0@68298|Syntrophomonadaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42M
k59_669231_1	670292.JH26_27055	4.11e-118	369.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,1JTYW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	MA20_06130	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
k59_1139237_1	246437.XP_006148270.1	5.24e-264	725.0	COG3588@1|root,KOG1557@2759|Eukaryota,38BBC@33154|Opisthokonta,3BAP7@33208|Metazoa,3CT8M@33213|Bilateria,47ZWM@7711|Chordata,48X1V@7742|Vertebrata,3J8BR@40674|Mammalia,35DPH@314146|Euarchontoglires	33208|Metazoa	G	fructose-bisphosphate aldolase activity	ALDOA	GO:0000003,GO:0000228,GO:0000785,GO:0000790,GO:0000792,GO:0001666,GO:0001775,GO:0002020,GO:0002237,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002576,GO:0003008,GO:0003012,GO:0003674,GO:0003779,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005720,GO:0005737,GO:0005739,GO:0005829,GO:0005856,GO:0005929,GO:0005975,GO:0005996,GO:0006000,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006936,GO:0006941,GO:0006950,GO:0006955,GO:0006996,GO:0007010,GO:0007015,GO:0007338,GO:0007339,GO:0008037,GO:0008064,GO:0008092,GO:0008150,GO:0008152,GO:0008360,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009435,GO:0009566,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009987,GO:0009988,GO:0010033,GO:0010639,GO:0012505,GO:0015629,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016192,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019725,GO:0019752,GO:0019899,GO:0019953,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030141,GO:0030246,GO:0030334,GO:0030335,GO:0030388,GO:0030832,GO:0030833,GO:0031091,GO:0031093,GO:0031410,GO:0031430,GO:0031514,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032271,GO:0032496,GO:0032501,GO:0032535,GO:0032787,GO:0032879,GO:0032940,GO:0032956,GO:0032970,GO:0032991,GO:0033043,GO:0033993,GO:0034315,GO:0034316,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034774,GO:0035036,GO:0035094,GO:0035686,GO:0036094,GO:0036126,GO:0036230,GO:0036293,GO:0040012,GO:0040017,GO:0042119,GO:0042221,GO:0042493,GO:0042592,GO:0042802,GO:0042866,GO:0042995,GO:0043207,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043230,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043292,GO:0043299,GO:0043312,GO:0043436,GO:0043627,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044433,GO:0044441,GO:0044444,GO:0044446,GO:0044449,GO:0044454,GO:0044463,GO:0044464,GO:0044703,GO:0045055,GO:0045321,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046716,GO:0046903,GO:0046939,GO:0048029,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051125,GO:0051126,GO:0051128,GO:0051129,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051270,GO:0051272,GO:0051289,GO:0051493,GO:0051494,GO:0051704,GO:0051707,GO:0055086,GO:0055114,GO:0060205,GO:0060249,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061827,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070061,GO:0070062,GO:0070482,GO:0070820,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090066,GO:0090407,GO:0097223,GO:0097435,GO:0097708,GO:0097729,GO:0099080,GO:0099081,GO:0099503,GO:0099512,GO:0101002,GO:0110053,GO:0120025,GO:0120038,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901700,GO:1902903,GO:1902904,GO:1903561,GO:1904724,GO:1904813,GO:2000145,GO:2000147	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
k59_865153_1	91464.S7335_3297	6.53e-29	108.0	COG1463@1|root,COG1463@2|Bacteria,1GFEH@1117|Cyanobacteria	1117|Cyanobacteria	Q	Protein of unknown function (DUF3465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3465
k59_865156_1	61853.ENSNLEP00000017141	3.03e-162	504.0	COG5069@1|root,KOG0518@2759|Eukaryota,38DME@33154|Opisthokonta,3B9WI@33208|Metazoa,3CS2N@33213|Bilateria,480F7@7711|Chordata,49204@7742|Vertebrata,3JD57@40674|Mammalia,35H1Q@314146|Euarchontoglires,4ME6N@9443|Primates	33208|Metazoa	Z	Filamin A, alpha	FLNA	GO:0000003,GO:0000226,GO:0000278,GO:0000280,GO:0000902,GO:0000904,GO:0001525,GO:0001568,GO:0001664,GO:0001775,GO:0001837,GO:0001944,GO:0001974,GO:0002009,GO:0002011,GO:0002064,GO:0002576,GO:0003006,GO:0003007,GO:0003674,GO:0003779,GO:0005080,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005730,GO:0005737,GO:0005794,GO:0005802,GO:0005829,GO:0005856,GO:0005884,GO:0005886,GO:0005903,GO:0005911,GO:0005938,GO:0006139,GO:0006351,GO:0006355,GO:0006356,GO:0006366,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006935,GO:0006937,GO:0006942,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007154,GO:0007165,GO:0007166,GO:0007186,GO:0007187,GO:0007188,GO:0007193,GO:0007195,GO:0007212,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007413,GO:0007417,GO:0007420,GO:0007507,GO:0007548,GO:0007596,GO:0007599,GO:0008016,GO:0008037,GO:0008038,GO:0008092,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008284,GO:0008406,GO:0008584,GO:0009058,GO:0009059,GO:0009299,GO:0009605,GO:0009611,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010638,GO:0010646,GO:0010647,GO:0010720,GO:0010721,GO:0010769,GO:0010770,GO:0010810,GO:0010811,GO:0010941,GO:0010959,GO:0010975,GO:0010977,GO:0012505,GO:0015459,GO:0015629,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0016192,GO:0016247,GO:0016477,GO:0016479,GO:0016482,GO:0017016,GO:0017048,GO:0017160,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019900,GO:0019901,GO:0021535,GO:0021932,GO:0021943,GO:0022008,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030030,GO:0030031,GO:0030036,GO:0030054,GO:0030154,GO:0030155,GO:0030168,GO:0030182,GO:0030334,GO:0030335,GO:0030424,GO:0030425,GO:0030426,GO:0030427,GO:0030855,GO:0030863,GO:0030902,GO:0031175,GO:0031267,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031344,GO:0031345,GO:0031523,GO:0031532,GO:0031628,GO:0031647,GO:0031674,GO:0031852,GO:0031974,GO:0031981,GO:0031984,GO:0032231,GO:0032233,GO:0032432,GO:0032501,GO:0032502,GO:0032774,GO:0032879,GO:0032940,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033267,GO:0034329,GO:0034330,GO:0034394,GO:0034613,GO:0034641,GO:0034645,GO:0034654,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0034987,GO:0034988,GO:0035239,GO:0035295,GO:0036477,GO:0040011,GO:0040012,GO:0040017,GO:0042060,GO:0042127,GO:0042176,GO:0042177,GO:0042221,GO:0042330,GO:0042391,GO:0042789,GO:0042802,GO:0042803,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043066,GO:0043067,GO:0043069,GO:0043113,GO:0043122,GO:0043123,GO:0043170,GO:0043198,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043266,GO:0043268,GO:0043269,GO:0043270,GO:0043292,GO:0043433,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044297,GO:0044319,GO:0044325,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044431,GO:0044444,GO:0044446,GO:0044448,GO:0044449,GO:0044463,GO:0044464,GO:0044782,GO:0044877,GO:0045022,GO:0045055,GO:0045137,GO:0045184,GO:0045185,GO:0045216,GO:0045595,GO:0045596,GO:0045597,GO:0045664,GO:0045665,GO:0045785,GO:0045892,GO:0045934,GO:0046332,GO:0046483,GO:0046546,GO:0046661,GO:0046903,GO:0046907,GO:0046983,GO:0048285,GO:0048365,GO:0048468,GO:0048471,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048608,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048729,GO:0048731,GO:0048762,GO:0048771,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050767,GO:0050768,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050817,GO:0050821,GO:0050878,GO:0050896,GO:0051015,GO:0051020,GO:0051049,GO:0051050,GO:0051090,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051179,GO:0051220,GO:0051225,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051270,GO:0051272,GO:0051493,GO:0051495,GO:0051641,GO:0051649,GO:0051668,GO:0051674,GO:0051716,GO:0051764,GO:0051960,GO:0051961,GO:0051962,GO:0055117,GO:0060008,GO:0060009,GO:0060065,GO:0060255,GO:0060271,GO:0060284,GO:0060306,GO:0060322,GO:0060372,GO:0060429,GO:0060485,GO:0060548,GO:0061038,GO:0061458,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070727,GO:0070925,GO:0071526,GO:0071704,GO:0071840,GO:0071944,GO:0072358,GO:0072359,GO:0072657,GO:0072659,GO:0080090,GO:0086004,GO:0090257,GO:0090304,GO:0090307,GO:0090504,GO:0090505,GO:0097368,GO:0097435,GO:0097440,GO:0097447,GO:0097458,GO:0097485,GO:0097659,GO:0098772,GO:0098791,GO:0098862,GO:0098900,GO:0098901,GO:0098903,GO:0098910,GO:0098927,GO:0099080,GO:0099081,GO:0099106,GO:0099512,GO:0099513,GO:0099568,GO:0099623,GO:0106030,GO:0110053,GO:0120025,GO:0120031,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0140014,GO:0150034,GO:1900024,GO:1900026,GO:1901360,GO:1901362,GO:1901379,GO:1901381,GO:1901576,GO:1902396,GO:1902414,GO:1902531,GO:1902533,GO:1902679,GO:1902850,GO:1902903,GO:1902905,GO:1903047,GO:1903115,GO:1903506,GO:1903507,GO:1903522,GO:1903779,GO:1904062,GO:1904064,GO:1905000,GO:1905031,GO:1990778,GO:2000026,GO:2000112,GO:2000113,GO:2000145,GO:2000147,GO:2000177,GO:2000179,GO:2001044,GO:2001046,GO:2001141,GO:2001222,GO:2001224	-	ko:K04437	ko04010,ko04510,ko05132,ko05205,map04010,map04510,map05132,map05205	-	-	-	ko00000,ko00001,ko04147,ko04812	-	-	-	CH,Filamin
k59_982935_1	1499967.BAYZ01000143_gene6136	1.77e-11	68.6	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,dCache_3
k59_982935_2	1038859.AXAU01000026_gene2330	8.36e-44	157.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TT1G@28211|Alphaproteobacteria,3JQQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_3394_1	983917.RGE_24120	8.94e-51	182.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1KKET@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_669254_1	1121015.N789_05640	2.79e-44	159.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,1X3MI@135614|Xanthomonadales	135614|Xanthomonadales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_1178772_1	616991.JPOO01000001_gene4348	2.08e-32	129.0	COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1HXGY@117743|Flavobacteriia,23H7J@178469|Arenibacter	976|Bacteroidetes	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
k59_424947_1	685035.ADAE01000018_gene498	1.69e-24	107.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U10R@28211|Alphaproteobacteria,2K0G1@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_424953_1	395492.Rleg2_4409	2.7e-60	202.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,2TQPC@28211|Alphaproteobacteria,4B700@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,rve
k59_771340_1	268748.I3RYR5_BPPRP	7.06e-91	279.0	4QAKM@10239|Viruses,4QUU7@35237|dsDNA viruses  no RNA stage,4QPEF@28883|Caudovirales,4QNER@10744|Podoviridae	10744|Podoviridae	S	DNA polymerase family A	-	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
k59_302041_1	1121405.dsmv_2768	8.33e-57	198.0	COG1807@1|root,COG1807@2|Bacteria,1MY0U@1224|Proteobacteria,42QGD@68525|delta/epsilon subdivisions,2WM6Q@28221|Deltaproteobacteria,2MJRD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_107412_1	1219084.AP014508_gene1836	1.74e-24	108.0	COG2199@1|root,COG3706@2|Bacteria,2GCEU@200918|Thermotogae	200918|Thermotogae	T	PFAM GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_12
k59_967955_1	72019.SARC_01293T0	1.96e-49	166.0	COG1171@1|root,KOG1251@2759|Eukaryota	2759|Eukaryota	E	serine racemase	SRR	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0036094,GO:0036211,GO:0036361,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.18	ko:K12235,ko:K12580,ko:K14951	ko00260,ko01100,ko03018,map00260,map01100,map03018	-	R00589	RC00302	ko00000,ko00001,ko01000,ko03019	3.A.3.10	-	-	PALP
k59_771362_1	335543.Sfum_1329	3.82e-62	209.0	COG0348@1|root,COG1143@1|root,COG1152@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1152@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MSKF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
k59_183287_1	471223.GWCH70_0069	5.41e-75	246.0	COG5433@1|root,COG5433@2|Bacteria,1TRZS@1239|Firmicutes,4HUF8@91061|Bacilli	91061|Bacilli	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4,DDE_Tnp_1_assoc
k59_425006_1	1123261.AXDW01000005_gene2698	9.63e-20	94.4	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,1S0DF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc
k59_26631_1	9541.XP_005575495.1	7.95e-225	625.0	KOG0443@1|root,KOG0443@2759|Eukaryota,38QM1@33154|Opisthokonta,3B9JY@33208|Metazoa,3D0D6@33213|Bilateria,47YVF@7711|Chordata,48X58@7742|Vertebrata,3J3W1@40674|Mammalia,35BPE@314146|Euarchontoglires,4MBYX@9443|Primates,3668V@314294|Cercopithecoidea	33208|Metazoa	Z	Macrophage-capping protein	CAPG	GO:0002376,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005814,GO:0005815,GO:0005819,GO:0005856,GO:0006950,GO:0006952,GO:0006955,GO:0008064,GO:0008150,GO:0008290,GO:0009987,GO:0010033,GO:0010639,GO:0015629,GO:0015630,GO:0016043,GO:0019904,GO:0022607,GO:0030030,GO:0030031,GO:0030139,GO:0030496,GO:0030832,GO:0030833,GO:0030834,GO:0030835,GO:0030837,GO:0031333,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0032271,GO:0032272,GO:0032535,GO:0032956,GO:0032970,GO:0032991,GO:0033043,GO:0034097,GO:0034341,GO:0042221,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043242,GO:0043244,GO:0043254,GO:0043933,GO:0044085,GO:0044087,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044464,GO:0044877,GO:0045087,GO:0045335,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051016,GO:0051128,GO:0051129,GO:0051493,GO:0051494,GO:0051693,GO:0051716,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071310,GO:0071345,GO:0071346,GO:0071840,GO:0072686,GO:0090066,GO:0090543,GO:0097708,GO:0110053,GO:1901879,GO:1901880,GO:1902903,GO:1902904	-	ko:K10368	-	-	-	-	ko00000,ko04147,ko04812	-	-	-	Gelsolin
k59_183306_1	1384054.N790_09535	4.83e-06	49.3	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria,1X4RC@135614|Xanthomonadales	135614|Xanthomonadales	N	transport system involved in gliding motility, auxiliary component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k59_1163392_1	519989.ECTPHS_06512	8.72e-34	124.0	COG1418@1|root,COG1418@2|Bacteria,1RH6M@1224|Proteobacteria,1S81F@1236|Gammaproteobacteria,1X2NE@135613|Chromatiales	135613|Chromatiales	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_497405_1	1329516.JPST01000036_gene3052	1.08e-56	189.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,27BNG@186824|Thermoactinomycetaceae	91061|Bacilli	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_340815_1	1121406.JAEX01000009_gene2631	1.68e-12	73.2	COG0745@1|root,COG3852@1|root,COG0745@2|Bacteria,COG3852@2|Bacteria,1R50S@1224|Proteobacteria,42NWW@68525|delta/epsilon subdivisions,2WMKY@28221|Deltaproteobacteria,2MH9F@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,PAS_3,Response_reg
k59_1124380_1	318167.Sfri_0030	6.47e-95	284.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,2QA4X@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760	Coprogen_oxidas
k59_185606_1	1117315.AHCA01000001_gene2216	3.38e-85	275.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,2Q03M@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_578555_1	391616.OA238_c34270	4.19e-60	194.0	COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,2U4I8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	PQ	Belongs to the peptidase S51 family	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
k59_110557_1	1123229.AUBC01000016_gene4286	1.85e-30	119.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,2TW9Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_110557_2	991905.SL003B_1470	3.02e-26	106.0	COG0577@1|root,COG0577@2|Bacteria,1PVW8@1224|Proteobacteria,2VG3T@28211|Alphaproteobacteria,4BR67@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k59_929934_1	399742.Ent638_1977	1.37e-07	55.1	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,3X00N@547|Enterobacter	1236|Gammaproteobacteria	E	Extracellular solute-binding protein	dppA2	-	-	ko:K02035,ko:K12368	ko02010,ko02024,ko02030,map02010,map02024,map02030	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_655868_1	864069.MicloDRAFT_00028010	1.21e-82	265.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TQSC@28211|Alphaproteobacteria,1JZ7I@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	UvrD/REP helicase N-terminal domain	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_971043_1	9541.XP_005544433.1	1.18e-88	265.0	KOG1280@1|root,KOG1280@2759|Eukaryota,3A02C@33154|Opisthokonta,3BPCX@33208|Metazoa,3D68J@33213|Bilateria,487XJ@7711|Chordata,491IU@7742|Vertebrata,3JEXP@40674|Mammalia,35CZP@314146|Euarchontoglires,4MJDI@9443|Primates,366TP@314294|Cercopithecoidea	33208|Metazoa	Z	Belongs to the stathmin family	STMN1	GO:0000003,GO:0000226,GO:0000278,GO:0000281,GO:0000902,GO:0000904,GO:0000910,GO:0001667,GO:0002064,GO:0002065,GO:0002066,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005875,GO:0006810,GO:0006928,GO:0006996,GO:0007010,GO:0007017,GO:0007018,GO:0007019,GO:0007049,GO:0007051,GO:0007052,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007399,GO:0007409,GO:0007416,GO:0007417,GO:0007420,GO:0007528,GO:0008017,GO:0008088,GO:0008092,GO:0008150,GO:0008277,GO:0008354,GO:0009605,GO:0009607,GO:0009615,GO:0009653,GO:0009888,GO:0009966,GO:0009968,GO:0009987,GO:0010631,GO:0010639,GO:0010646,GO:0010648,GO:0010970,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016477,GO:0019953,GO:0022008,GO:0022402,GO:0022411,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030104,GO:0030154,GO:0030182,GO:0030705,GO:0030707,GO:0030855,GO:0031109,GO:0031110,GO:0031111,GO:0031113,GO:0031115,GO:0031175,GO:0031333,GO:0031594,GO:0032091,GO:0032231,GO:0032232,GO:0032271,GO:0032272,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032886,GO:0032956,GO:0032970,GO:0032984,GO:0032989,GO:0032990,GO:0032991,GO:0033043,GO:0033561,GO:0035023,GO:0035024,GO:0035556,GO:0040007,GO:0040011,GO:0042592,GO:0042995,GO:0043005,GO:0043207,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043393,GO:0043588,GO:0043624,GO:0043933,GO:0044085,GO:0044087,GO:0044092,GO:0044093,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045202,GO:0045744,GO:0046578,GO:0046580,GO:0046907,GO:0048012,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048609,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0048871,GO:0048878,GO:0050789,GO:0050794,GO:0050808,GO:0050878,GO:0050891,GO:0050896,GO:0051056,GO:0051058,GO:0051098,GO:0051099,GO:0051100,GO:0051124,GO:0051128,GO:0051129,GO:0051179,GO:0051234,GO:0051261,GO:0051270,GO:0051272,GO:0051301,GO:0051492,GO:0051493,GO:0051494,GO:0051497,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0060322,GO:0060429,GO:0061436,GO:0061564,GO:0061640,GO:0065007,GO:0065008,GO:0065009,GO:0070494,GO:0070495,GO:0070507,GO:0071840,GO:0090130,GO:0090132,GO:0097435,GO:0097458,GO:0099111,GO:0110020,GO:0110053,GO:0120025,GO:0120036,GO:0120039,GO:1902531,GO:1902532,GO:1902850,GO:1902903,GO:1902904,GO:1903047,GO:1904424,GO:1905097,GO:1905098	-	ko:K04381	ko04010,ko05206,map04010,map05206	-	-	-	ko00000,ko00001,ko04812	-	-	-	Stathmin
k59_265761_1	118797.XP_007461093.1	1.43e-123	352.0	COG2157@1|root,KOG0829@2759|Eukaryota,38FEA@33154|Opisthokonta,3BD11@33208|Metazoa,3CVTY@33213|Bilateria,486BM@7711|Chordata,49261@7742|Vertebrata,3JCPM@40674|Mammalia,4J6J2@91561|Cetartiodactyla	33208|Metazoa	J	Ribosomal protein L18a	RPL18A	GO:0000184,GO:0000956,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015934,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0042221,GO:0042493,GO:0042788,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060255,GO:0065007,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:0097327,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02882	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18A
k59_542847_1	156889.Mmc1_2587	1.54e-83	257.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW7X@1224|Proteobacteria,2TTH8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG3335 Transposase and inactivated derivatives	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32
k59_1049739_1	1415778.JQMM01000001_gene958	3.94e-84	268.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1J5DB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
k59_1248053_1	936455.KI421499_gene2235	3.37e-18	83.2	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TSE3@28211|Alphaproteobacteria,3JS0H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
k59_428268_1	1121087.AUCK01000002_gene2560	2.87e-21	97.4	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HBR0@91061|Bacilli,1ZQ9D@1386|Bacillus	91061|Bacilli	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
k59_971069_1	497964.CfE428DRAFT_1237	9.13e-95	290.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_428282_1	1041146.ATZB01000008_gene2192	3.77e-157	462.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_110599_1	742743.HMPREF9453_00273	4.05e-05	49.3	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4H45P@909932|Negativicutes	909932|Negativicutes	C	iron-sulfur cluster-binding protein	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
k59_110599_2	269797.Mbar_A1581	4.25e-09	57.4	COG1600@1|root,arCOG02740@2157|Archaea,2XVPE@28890|Euryarchaeota,2NAD1@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_578610_1	1121405.dsmv_2238	3.23e-85	262.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2MHX4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	dsrP	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_695975_1	523791.Kkor_0383	1.53e-49	176.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1XMZK@135619|Oceanospirillales	135619|Oceanospirillales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_1049774_1	258594.RPA1233	1.33e-62	200.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3JUH1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	MA20_19430	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,DLIC
k59_971100_2	983545.Glaag_1385	1.61e-21	89.4	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,4679Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Biopolymer transport protein	tolR	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
k59_185677_1	1121405.dsmv_2787	2.44e-101	312.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,2MI30@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_734914_1	1500897.JQNA01000002_gene697	2.7e-96	294.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2VH6U@28216|Betaproteobacteria,1K5SV@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
k59_110614_2	575788.VS_0194	1.17e-67	219.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1XSR4@135623|Vibrionales	135623|Vibrionales	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	ko:K12982	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_460815_1	584708.Apau_1992	6.35e-08	57.0	COG4630@1|root,COG4630@2|Bacteria,3TAMB@508458|Synergistetes	508458|Synergistetes	C	CO dehydrogenase flavoprotein	-	-	1.17.1.4,1.2.5.3	ko:K03518,ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
k59_460815_2	293826.Amet_0682	7.67e-53	171.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia,36K17@31979|Clostridiaceae	186801|Clostridia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
k59_971122_1	203122.Sde_2319	6.39e-59	186.0	COG0454@1|root,COG0456@2|Bacteria,1N79D@1224|Proteobacteria,1SG34@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
k59_696015_2	1120983.KB894574_gene1005	1.63e-15	78.2	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,1JPHB@119043|Rhodobiaceae	28211|Alphaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_734944_1	1123511.KB905872_gene1845	6.61e-108	325.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H53T@909932|Negativicutes	909932|Negativicutes	L	RNA-directed DNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_110653_1	118161.KB235922_gene2456	1.76e-35	137.0	2C69V@1|root,2Z9DY@2|Bacteria,1G4DI@1117|Cyanobacteria	1117|Cyanobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_734963_1	1121405.dsmv_3251	1.16e-85	275.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2MHZG@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
k59_811956_1	1120705.FG95_01011	2.39e-11	68.9	COG1228@1|root,COG1228@2|Bacteria,1R40Z@1224|Proteobacteria,2U85Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_811957_1	879212.DespoDRAFT_03596	1.87e-88	271.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2WJJA@28221|Deltaproteobacteria,2MHP8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_930149_1	269799.Gmet_0995	1.71e-11	64.3	COG2853@1|root,COG2853@2|Bacteria,1QV20@1224|Proteobacteria	1224|Proteobacteria	M	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_930149_2	1254432.SCE1572_20250	4.16e-20	93.6	COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_578766_2	1446473.JHWH01000002_gene1680	2.62e-32	117.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,2U70I@28211|Alphaproteobacteria,2PVZ0@265|Paracoccus	28211|Alphaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
k59_428500_1	1121878.AUGL01000030_gene3457	1.35e-14	78.6	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,MASE1,PAS_4,PAS_9,Reg_prop,Y_Y_Y
k59_29619_1	1304888.ATWF01000001_gene2240	5.5e-16	79.7	COG0702@1|root,COG0702@2|Bacteria,2GFB1@200930|Deferribacteres	200930|Deferribacteres	M	NAD(P)H-binding	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
k59_68454_1	1121918.ARWE01000001_gene3052	7.12e-44	147.0	COG4665@1|root,COG4665@2|Bacteria,1REH8@1224|Proteobacteria,43B1K@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	COGs COG4665 TRAP-type mannitol chloroaromatic compound transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_68454_2	760154.Sulba_0491	2.31e-55	186.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,42MQU@68525|delta/epsilon subdivisions,2YMC7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	Q	TRAP transporter, DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
k59_460941_1	96561.Dole_0493	6.54e-43	155.0	COG3233@1|root,COG3233@2|Bacteria,1RB7V@1224|Proteobacteria,42RBC@68525|delta/epsilon subdivisions,2WMQB@28221|Deltaproteobacteria,2MJK1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1014530_1	292415.Tbd_2201	9.01e-61	199.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria,1KSI6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_304777_1	455632.SGR_3264	7.77e-41	159.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,417CI@629295|Streptomyces griseus group	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
k59_185843_1	933262.AXAM01000038_gene897	7.07e-19	84.7	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42QGK@68525|delta/epsilon subdivisions,2WMC7@28221|Deltaproteobacteria,2MHPR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	L11 methyltransferase	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_185843_2	1121405.dsmv_0661	8.02e-46	153.0	COG0517@1|root,COG0517@2|Bacteria,1PDG6@1224|Proteobacteria,42QQ0@68525|delta/epsilon subdivisions,2WMQ6@28221|Deltaproteobacteria,2MKN2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
k59_1166622_1	288000.BBta_4099	7.15e-65	206.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2TS88@28211|Alphaproteobacteria,3JTFT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	TatD related DNase	MA20_29410	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_1166622_2	717785.HYPMC_2033	2.99e-15	73.2	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2TQQN@28211|Alphaproteobacteria,3N6M2@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
k59_500525_1	1416760.AYMS01000060_gene2211	4.06e-12	66.2	COG1670@1|root,COG1670@2|Bacteria,4NNXN@976|Bacteroidetes,1I1KC@117743|Flavobacteriia,47I9W@76831|Myroides	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
k59_500525_2	675814.VIC_002452	2.59e-53	170.0	COG3324@1|root,COG3324@2|Bacteria,1N7Q5@1224|Proteobacteria,1SB3Z@1236|Gammaproteobacteria,1XX54@135623|Vibrionales	135623|Vibrionales	S	enzyme related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_460988_1	272624.lpg0004	1.78e-90	288.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1JCKS@118969|Legionellales	118969|Legionellales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_774495_1	351348.Maqu_2787	9.86e-95	298.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,464Q5@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_578841_1	425104.Ssed_2791	1.89e-43	160.0	COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,1RMJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
k59_185878_1	56780.SYN_01263	9.48e-102	308.0	COG1127@1|root,COG2199@1|root,COG1127@2|Bacteria,COG2199@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MQX9@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
k59_244440_1	1040986.ATYO01000013_gene5107	7.98e-18	79.3	COG1426@1|root,COG1426@2|Bacteria,1RD2P@1224|Proteobacteria,2U8WI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
k59_479336_1	1121413.JMKT01000011_gene2395	3.37e-101	304.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,42MRB@68525|delta/epsilon subdivisions,2WIZD@28221|Deltaproteobacteria,2M8BR@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	reductase, dissimilatory-type alpha subunit	dsrA	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
k59_1106374_1	566466.NOR53_2053	1.56e-54	191.0	COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T1MR@1236|Gammaproteobacteria,1J7KC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_50177_1	266265.Bxe_C0490	2.78e-49	172.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2VWYN@28216|Betaproteobacteria,1K8UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	Transposase_20
k59_1226730_1	338966.Ppro_2303	3.54e-74	248.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,43TCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1031332_1	1232437.KL662042_gene1987	1.16e-64	207.0	COG3387@1|root,COG3387@2|Bacteria,1NB01@1224|Proteobacteria,42N48@68525|delta/epsilon subdivisions,2WJRY@28221|Deltaproteobacteria,2MHXM@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_598984_1	3075.A0A087SSY7	9.96e-36	141.0	COG0318@1|root,COG0604@1|root,COG3321@1|root,KOG1176@2759|Eukaryota,KOG1197@2759|Eukaryota,KOG1198@2759|Eukaryota,KOG1202@2759|Eukaryota,37NZS@33090|Viridiplantae,34PB6@3041|Chlorophyta	3041|Chlorophyta	I	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N_2,AMP-binding,AMP-binding_C,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
k59_1068682_1	314285.KT71_06252	9.38e-31	126.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S876@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_637958_1	56780.SYN_00764	6.26e-47	164.0	29WN3@1|root,30I8X@2|Bacteria,1R4H3@1224|Proteobacteria,42Q38@68525|delta/epsilon subdivisions,2WM8N@28221|Deltaproteobacteria,2MRD3@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_285260_1	1232437.KL662010_gene1572	7.01e-92	285.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2MI74@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
k59_716893_1	61853.ENSNLEP00000017438	1.65e-123	362.0	COG5190@1|root,KOG2832@2759|Eukaryota,38DKE@33154|Opisthokonta,3BF5Q@33208|Metazoa,3CTWY@33213|Bilateria,480RM@7711|Chordata,493MV@7742|Vertebrata,3J82Y@40674|Mammalia,35D0I@314146|Euarchontoglires,4MMWX@9443|Primates	33208|Metazoa	C	Translocase of inner mitochondrial membrane 50	TIMM50	GO:0001836,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0004725,GO:0005102,GO:0005126,GO:0005134,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005744,GO:0006464,GO:0006470,GO:0006605,GO:0006626,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006886,GO:0006915,GO:0006996,GO:0007005,GO:0007006,GO:0007154,GO:0007165,GO:0008104,GO:0008150,GO:0008152,GO:0008219,GO:0008637,GO:0009987,GO:0012501,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016311,GO:0016604,GO:0016607,GO:0016787,GO:0016788,GO:0016791,GO:0017038,GO:0019538,GO:0019866,GO:0023052,GO:0030150,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0035335,GO:0036211,GO:0042578,GO:0042886,GO:0043021,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044451,GO:0044455,GO:0044464,GO:0044743,GO:0044877,GO:0045184,GO:0046907,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055085,GO:0061024,GO:0065002,GO:0065007,GO:0070013,GO:0070585,GO:0070727,GO:0070851,GO:0071702,GO:0071704,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0097190,GO:0098796,GO:0098798,GO:0098800,GO:0140096,GO:1901564,GO:1990542	-	ko:K17496	-	-	-	-	ko00000,ko02000,ko03029	3.A.8.1	-	-	NIF
k59_1186695_1	223926.28808970	1.87e-49	174.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,1SM5A@1236|Gammaproteobacteria,1XVNU@135623|Vibrionales	135623|Vibrionales	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_911787_1	1122194.AUHU01000002_gene2629	6.05e-06	48.5	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,46547@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
k59_911787_2	1265313.HRUBRA_02047	9.24e-07	48.5	COG2991@1|root,COG2991@2|Bacteria	2|Bacteria	H	Protein conserved in bacteria	Z012_07620	-	2.7.1.180	ko:K03734,ko:K05952	-	-	-	-	ko00000,ko01000	-	-	-	NqrM
k59_285304_1	981384.AEYW01000001_gene1602	4.46e-77	248.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_951379_1	1232437.KL662016_gene1041	2.92e-49	169.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,43B11@68525|delta/epsilon subdivisions,2X6F7@28221|Deltaproteobacteria,2MJMV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_1226834_1	1408428.JNJP01000006_gene2581	4.12e-30	122.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,42PEY@68525|delta/epsilon subdivisions,2WJJ3@28221|Deltaproteobacteria,2MAY5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_285315_2	187272.Mlg_2625	9.08e-30	115.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,1SBT1@1236|Gammaproteobacteria,1WYAZ@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
k59_755357_1	640081.Dsui_3260	3.26e-190	550.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,2KV9E@206389|Rhodocyclales	206389|Rhodocyclales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_1226851_1	1177154.Y5S_01704	3.46e-85	287.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_90207_1	631362.Thi970DRAFT_01227	6.75e-16	82.8	COG0834@1|root,COG5002@1|root,COG0834@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1X2TY@135613|Chromatiales	1236|Gammaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,HAMP,HATPase_c,HTH_18,HisKA,Hpt,MASE1,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Phosphonate-bd,Reg_prop,Response_reg,SBP_bac_3,TarH,Y_Y_Y
k59_285342_1	1342302.JASC01000014_gene785	3.27e-38	140.0	COG2353@1|root,COG2885@1|root,COG2353@2|Bacteria,COG2885@2|Bacteria,1MZDI@1224|Proteobacteria,2U1GS@28211|Alphaproteobacteria,3ZWYW@60136|Sulfitobacter	28211|Alphaproteobacteria	M	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,YceI
k59_1226872_1	1328313.DS2_08375	4.52e-54	192.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMSH@1236|Gammaproteobacteria,46579@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Alpha-amylase domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,PUD
k59_794412_1	1121918.ARWE01000001_gene1528	7.4e-52	179.0	2AFPW@1|root,315RN@2|Bacteria,1N1K1@1224|Proteobacteria,42WWK@68525|delta/epsilon subdivisions,2WSXP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1186753_1	63737.Npun_F5467	3.22e-50	181.0	COG2202@1|root,COG3852@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,1HTQ5@1161|Nostocales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_403613_1	511051.CSE_10010	7.14e-68	219.0	COG0017@1|root,COG0017@2|Bacteria	2|Bacteria	J	Asparaginyl-tRNA synthetase	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_206885_1	694431.DESACE_07500	4.12e-75	232.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,42PYG@68525|delta/epsilon subdivisions,2WIRC@28221|Deltaproteobacteria,2M6VM@213113|Desulfurellales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_50292_1	96561.Dole_2296	1.23e-21	92.8	COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,43BRN@68525|delta/epsilon subdivisions,2X72H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
k59_246407_1	1205753.A989_17308	5.71e-84	256.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1X38I@135614|Xanthomonadales	135614|Xanthomonadales	V	Transport permease protein	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k59_481312_1	96561.Dole_2132	2.54e-49	164.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42QN5@68525|delta/epsilon subdivisions,2WMD7@28221|Deltaproteobacteria,2MJC9@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_206898_1	384765.SIAM614_02161	3.12e-181	508.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_755408_1	247633.GP2143_04173	1.22e-66	220.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_90254_1	400682.PAC_15718717	1.8e-83	251.0	COG2036@1|root,KOG1745@2759|Eukaryota,39ZTV@33154|Opisthokonta,3BPC3@33208|Metazoa	33208|Metazoa	B	Histone H3.3-like	-	-	-	ko:K11253	ko05034,ko05202,ko05322,map05034,map05202,map05322	-	-	-	ko00000,ko00001,ko03036,ko04147	-	-	-	Histone
k59_128708_1	675817.VDA_001312	1.29e-62	200.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1XSG2@135623|Vibrionales	135623|Vibrionales	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_128708_2	396588.Tgr7_0849	7.16e-09	53.5	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1WYID@135613|Chromatiales	135613|Chromatiales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
k59_599112_1	1123376.AUIU01000001_gene791	2.49e-66	207.0	COG0378@1|root,COG0378@2|Bacteria,3J128@40117|Nitrospirae	40117|Nitrospirae	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_755420_1	1286093.C266_16875	4.12e-33	129.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,1K2GP@119060|Burkholderiaceae	28216|Betaproteobacteria	I	fatty acid desaturase	ole1	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
k59_90266_1	862908.BMS_2024	8.74e-30	116.0	COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,42QZX@68525|delta/epsilon subdivisions,2WN5T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
k59_1108340_1	670292.JH26_02315	3.68e-10	67.8	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
k59_1031550_1	177437.HRM2_43560	5.31e-50	173.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,42T2F@68525|delta/epsilon subdivisions,2WPGM@28221|Deltaproteobacteria,2MKRM@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
k59_559647_1	1040982.AXAL01000022_gene6413	3.7e-56	188.0	COG0520@1|root,COG0520@2|Bacteria,1PNGA@1224|Proteobacteria,2U1V6@28211|Alphaproteobacteria,43MYF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_1186842_1	1121405.dsmv_3691	4.78e-97	293.0	COG3547@1|root,COG3547@2|Bacteria,1NP2U@1224|Proteobacteria,43A5Q@68525|delta/epsilon subdivisions,2X2AM@28221|Deltaproteobacteria,2MPDW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_833895_1	502347.ESCAB7627_0934	5.99e-31	120.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,3XN1C@561|Escherichia	1236|Gammaproteobacteria	H	Involved in the removal of 5-formyltetrahydrofolate. In vitro, it is a potent inhibitor of various folate-dependent enzymes in the C1 metabolism network and in vivo it might function as a folate storage. 5-formyltetrahydrofolate is also used as an antifolate rescue agent in cancer chemotherapy. Catalyzes the irreversible ATP-dependent transformation of 5- formyltetrahydrofolate (5-CHO-THF) to form 5,10- methenyltetrahydrofolate (5,10-CH THF). The reverse reaction is catalyzed by the serine hydroxymethyltransferase GlyA (SHMT)	ygfA	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298	5-FTHF_cyc-lig
k59_717045_1	981384.AEYW01000004_gene1772	2.45e-93	290.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,4NCZP@97050|Ruegeria	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_1031600_1	314231.FP2506_02515	2.85e-59	192.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,2PKCR@255475|Aurantimonadaceae	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
k59_717056_2	1379281.AVAG01000012_gene1500	3.01e-22	91.7	COG0745@1|root,COG0745@2|Bacteria,1NE8H@1224|Proteobacteria,42NEH@68525|delta/epsilon subdivisions,2WK1M@28221|Deltaproteobacteria,2M7RK@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2,Response_reg
k59_717056_3	1304872.JAGC01000009_gene20	6.64e-24	100.0	COG0730@1|root,COG0730@2|Bacteria,1NJ47@1224|Proteobacteria,42QRS@68525|delta/epsilon subdivisions,2WN5M@28221|Deltaproteobacteria,2MGEZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_833925_1	1122164.JHWF01000024_gene2589	2.19e-15	77.4	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,1SYTB@1236|Gammaproteobacteria,1JC5J@118969|Legionellales	118969|Legionellales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
k59_833925_2	1232410.KI421414_gene2844	2.33e-18	86.3	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,43SZS@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
k59_285483_1	1265313.HRUBRA_01348	1.16e-49	173.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
k59_206992_2	1121373.KB903638_gene915	1.34e-31	111.0	COG1942@1|root,COG1942@2|Bacteria,4NV4Q@976|Bacteroidetes,47SGK@768503|Cytophagia	976|Bacteroidetes	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
k59_324566_1	1121439.dsat_2723	5.8e-32	112.0	COG1773@1|root,COG1773@2|Bacteria,1NES3@1224|Proteobacteria,42VN9@68525|delta/epsilon subdivisions,2WRT2@28221|Deltaproteobacteria,2MCJQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the rubredoxin family	-	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114	-	-	-	-	-	-	-	-	-	-	Rubredoxin
k59_324566_2	1122622.ATWJ01000007_gene1776	3.03e-20	87.4	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4FG64@85021|Intrasporangiaceae	201174|Actinobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,LMWPc
k59_992135_1	472759.Nhal_2009	7.04e-56	189.0	COG4783@1|root,COG4783@2|Bacteria,1RAJB@1224|Proteobacteria,1SA1F@1236|Gammaproteobacteria,1X0C0@135613|Chromatiales	135613|Chromatiales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_911964_1	344747.PM8797T_05430	7.03e-46	164.0	COG2170@1|root,COG2170@2|Bacteria,2IXAU@203682|Planctomycetes	203682|Planctomycetes	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
k59_324571_1	933262.AXAM01000002_gene508	3.08e-41	155.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,2MI01@213118|Desulfobacterales	28221|Deltaproteobacteria	S	metal-dependent phosphohydrolase 7TM intracellular region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_873023_1	330214.NIDE1103	1.39e-75	235.0	COG0115@1|root,COG0115@2|Bacteria,3J0BM@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_911974_1	396588.Tgr7_1911	1.08e-106	318.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1WWWT@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_911974_2	1265503.KB905175_gene3998	4.19e-32	120.0	COG3339@1|root,COG3339@2|Bacteria,1RAN7@1224|Proteobacteria,1S291@1236|Gammaproteobacteria,2Q6RN@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
k59_911974_3	1123073.KB899241_gene3327	4.16e-15	72.8	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,1RMVC@1236|Gammaproteobacteria,1XCI7@135614|Xanthomonadales	135614|Xanthomonadales	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
k59_207026_1	483219.LILAB_32190	5.53e-53	174.0	COG4974@1|root,COG4974@2|Bacteria,1RC0C@1224|Proteobacteria,42W1W@68525|delta/epsilon subdivisions,2WRTZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_364336_1	396588.Tgr7_2316	4.04e-17	74.7	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1WZ6K@135613|Chromatiales	135613|Chromatiales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
k59_364336_2	765913.ThidrDRAFT_1746	2.75e-35	122.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1WZA0@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_364336_3	1122134.KB893651_gene1787	1.31e-70	214.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,1XJIX@135619|Oceanospirillales	135619|Oceanospirillales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_364336_4	1249627.D779_3561	4.08e-15	70.1	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1WYKG@135613|Chromatiales	135613|Chromatiales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
k59_638203_1	29486.NJ56_12275	2.41e-11	60.8	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,41G5B@629|Yersinia	1236|Gammaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006654,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046473,GO:0046474,GO:0046486,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
k59_638203_2	1318628.MARLIPOL_13674	4.63e-38	135.0	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,1SAU1@1236|Gammaproteobacteria,466ER@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	COG0671 Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
k59_1108463_1	207954.MED92_02479	2.04e-73	229.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,1RQN1@1236|Gammaproteobacteria,1XHGV@135619|Oceanospirillales	135619|Oceanospirillales	S	C4-dicarboxylate ABC transporter substrate-binding protein	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_992199_1	1335760.ASTG01000021_gene2840	1.12e-25	111.0	COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,2U296@28211|Alphaproteobacteria,2K5S0@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
k59_364353_1	1286106.MPL1_06467	1.88e-109	323.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,4608I@72273|Thiotrichales	72273|Thiotrichales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_834018_1	247633.GP2143_04420	9.26e-52	177.0	COG5505@1|root,COG5505@2|Bacteria,1RAF4@1224|Proteobacteria,1S8PC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
k59_306166_1	396588.Tgr7_2973	3.56e-60	196.0	COG0258@1|root,COG0258@2|Bacteria,1RAAR@1224|Proteobacteria,1S2FH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG0258 5'-3' exonuclease (including N-terminal domain of PolI)	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
k59_1051306_1	519989.ECTPHS_07326	2.92e-80	259.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1WWI3@135613|Chromatiales	135613|Chromatiales	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_580136_1	1042377.AFPJ01000030_gene464	1.98e-38	139.0	28NHW@1|root,2ZBJG@2|Bacteria,1RBJB@1224|Proteobacteria,1S31B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_775834_1	644968.DFW101_0478	3.51e-88	280.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2M88M@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_148310_1	713586.KB900536_gene2636	4.02e-53	180.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1WWTH@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_306189_1	335283.Neut_1576	2.19e-77	243.0	COG0535@1|root,COG0535@2|Bacteria,1MXM1@1224|Proteobacteria,2VNRX@28216|Betaproteobacteria,371QM@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF3463)	hpnH	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_14,Radical_SAM
k59_1168102_1	1265505.ATUG01000002_gene2614	5.12e-29	106.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MKI6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_1168105_1	941449.dsx2_3189	5.67e-62	196.0	COG2009@1|root,2ZBTX@2|Bacteria,1RB22@1224|Proteobacteria,42NAY@68525|delta/epsilon subdivisions,2WMPM@28221|Deltaproteobacteria,2M7WC@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM fumarate reductase respiratory complex	-	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
k59_31016_1	1265505.ATUG01000002_gene1613	2.49e-61	211.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,1MU0N@1224|Proteobacteria,43CWU@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_775867_1	643562.Daes_0872	2.93e-12	65.9	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42MXZ@68525|delta/epsilon subdivisions,2WJWG@28221|Deltaproteobacteria,2MANP@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_430167_1	1537994.JQFW01000045_gene2320	5.84e-10	59.7	COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,1RS0Q@1236|Gammaproteobacteria,4653N@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_430167_2	1282362.AEAC466_01015	7.66e-34	126.0	COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,2TSG2@28211|Alphaproteobacteria,2KHVD@204458|Caulobacterales	28211|Alphaproteobacteria	S	transcription factor jumonji	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
k59_229902_1	575540.Isop_2879	6.35e-60	203.0	COG1115@1|root,COG1115@2|Bacteria,2IX3I@203682|Planctomycetes	203682|Planctomycetes	U	COG1115 Na alanine symporter	dagA	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
k59_775882_1	177437.HRM2_24470	1.75e-31	120.0	COG2357@1|root,COG2357@2|Bacteria,1RCHE@1224|Proteobacteria,42PPK@68525|delta/epsilon subdivisions,2WJBS@28221|Deltaproteobacteria,2MHSG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
k59_775882_2	865937.Gilli_3121	2.86e-14	72.4	COG2152@1|root,COG2152@2|Bacteria,4PIDW@976|Bacteroidetes,1ICCR@117743|Flavobacteriia,2P7P2@244698|Gillisia	976|Bacteroidetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
k59_813506_2	207954.MED92_08662	1.62e-40	144.0	COG0583@1|root,COG0583@2|Bacteria,1MX2A@1224|Proteobacteria,1RPHN@1236|Gammaproteobacteria,1XIRV@135619|Oceanospirillales	135619|Oceanospirillales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_1088570_1	930169.B5T_01198	3.3e-70	228.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1XING@135619|Oceanospirillales	135619|Oceanospirillales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_619829_1	1496688.ER33_03045	3.57e-28	109.0	COG0500@1|root,COG2226@2|Bacteria,1G60J@1117|Cyanobacteria,22T7D@167375|Cyanobium	1117|Cyanobacteria	Q	SAM (And some other nucleotide) binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_619829_2	391615.ABSJ01000024_gene258	2.21e-24	99.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1J5TZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0501 Zn-dependent protease with chaperone function	Z012_09445	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_1128690_2	338966.Ppro_1151	8.1e-19	87.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,43SX6@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase domain protein	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
k59_385856_1	269799.Gmet_0792	8.22e-47	156.0	COG2945@1|root,COG2945@2|Bacteria,1QY8I@1224|Proteobacteria,43CAB@68525|delta/epsilon subdivisions,2X7KV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1168187_1	338966.Ppro_0400	4.79e-28	114.0	28PW7@1|root,32EDN@2|Bacteria,1N0AP@1224|Proteobacteria,42UF5@68525|delta/epsilon subdivisions,2WQ2P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
k59_187293_1	1121878.AUGL01000002_gene2181	3.05e-29	120.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_1168201_1	566466.NOR53_2235	2.68e-57	197.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,1J7HW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	COG1472 Beta-glucosidase-related glycosidases	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_931733_1	404589.Anae109_3636	1.85e-81	257.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2WJE2@28221|Deltaproteobacteria,2YXXW@29|Myxococcales	28221|Deltaproteobacteria	P	ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_501974_1	1114970.PSF113_1165	4.08e-64	209.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,1S1FB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	yagA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3
k59_1051441_1	1117319.PSPO_00747	5.33e-13	67.4	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,2Q0J9@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Modulates RecA activity	recX	GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
k59_1051441_2	1049564.TevJSym_aa02290	3.04e-76	249.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1J58G@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_306267_1	933262.AXAM01000004_gene2364	2.75e-26	106.0	COG0438@1|root,COG0438@2|Bacteria,1R8YI@1224|Proteobacteria,42N8I@68525|delta/epsilon subdivisions,2WIYJ@28221|Deltaproteobacteria,2MMJB@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_31126_1	1452718.JBOY01000024_gene350	1.96e-52	186.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_931775_1	1205908.AKXW01000108_gene1243	1.98e-26	112.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1XTPW@135623|Vibrionales	135623|Vibrionales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23,HlyD_D4
k59_430308_1	644966.Tmar_1301	8.67e-42	151.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,3WCIT@538999|Clostridiales incertae sedis	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_853952_1	96561.Dole_0609	2.18e-97	295.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2MI9Q@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_657549_1	309801.trd_A0748	5.08e-45	157.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_31151_1	1267005.KB911257_gene858	7.07e-63	208.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria,3N66F@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_893703_1	1121106.JQKB01000027_gene1866	2.75e-90	273.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria,2VF18@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_230076_1	760568.Desku_1693	8.98e-61	201.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,260K4@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_31160_1	583355.Caka_2179	4.04e-72	232.0	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
k59_386000_1	314278.NB231_06950	3.68e-85	265.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1WW5M@135613|Chromatiales	135613|Chromatiales	EH	Anthranilate synthase component I	-	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_1016066_1	941449.dsx2_0270	3.84e-27	112.0	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,42MBI@68525|delta/epsilon subdivisions,2WIZ9@28221|Deltaproteobacteria,2M843@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Cation transporter	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
k59_1249928_1	439235.Dalk_3288	1.18e-98	313.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2MIFX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
k59_462506_1	1096769.Pelub83DRAFT_0983	3.66e-83	256.0	COG3842@1|root,COG3842@2|Bacteria,1QU06@1224|Proteobacteria,2TWIE@28211|Alphaproteobacteria,4BTES@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K17324	ko02010,map02010	M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.35	-	-	ABC_tran,TOBE_2
k59_736720_1	1282876.BAOK01000001_gene2862	5.28e-05	45.8	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2TS0E@28211|Alphaproteobacteria,4BPWQ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_736720_2	1283300.ATXB01000002_gene3088	1.37e-48	165.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,1RMFS@1236|Gammaproteobacteria,1XDJ1@135618|Methylococcales	1236|Gammaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0750,iAPECO1_1312.APECO1_1338,iB21_1397.B21_00692,iBWG_1329.BWG_0602,iECBD_1354.ECBD_2917,iECB_1328.ECB_00703,iECDH10B_1368.ECDH10B_0817,iECDH1ME8569_1439.ECDH1ME8569_0703,iECD_1391.ECD_00703,iECED1_1282.ECED1_0711,iECOK1_1307.ECOK1_0750,iECP_1309.ECP_0761,iECS88_1305.ECS88_0766,iECSP_1301.ECSP_0802,iECs_1301.ECs0778,iETEC_1333.ETEC_0754,iEcDH1_1363.EcDH1_2892,iEcolC_1368.EcolC_2912,iJN746.PP_1231,iJO1366.b0750,iJR904.b0750,iUMN146_1321.UM146_13905,iUTI89_1310.UTI89_C0747,iY75_1357.Y75_RS03905,iZ_1308.Z0919	NadA
k59_854012_1	113395.AXAI01000002_gene5234	2.48e-120	352.0	COG2141@1|root,COG2141@2|Bacteria,1QZQ7@1224|Proteobacteria,2UQHY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_697805_2	986075.CathTA2_2645	2.36e-57	188.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli	91061|Bacilli	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_1088838_1	232346.JHQL01000006_gene3011	1.26e-21	92.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,1XHIU@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
k59_187475_1	1500257.JQNM01000021_gene2618	6.74e-66	214.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,4B8B9@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
k59_931911_2	640081.Dsui_1869	5.72e-36	124.0	2DNV8@1|root,32ZAX@2|Bacteria,1R3MW@1224|Proteobacteria,2VWAR@28216|Betaproteobacteria,2KWYT@206389|Rhodocyclales	206389|Rhodocyclales	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
k59_777925_1	391616.OA238_c42560	5.39e-13	69.3	COG3128@1|root,COG3128@2|Bacteria,1R4AI@1224|Proteobacteria,2U4W7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07336	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3
k59_114368_1	96561.Dole_2273	2.98e-97	295.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2MJ5M@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_71827_2	1265505.ATUG01000001_gene3330	1.36e-15	74.7	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,42TXX@68525|delta/epsilon subdivisions,2WQBC@28221|Deltaproteobacteria,2MK1I@213118|Desulfobacterales	28221|Deltaproteobacteria	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4,Peptidase_S15
k59_855882_1	933262.AXAM01000002_gene546	4.4e-49	174.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,2MIKW@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_189346_1	1121405.dsmv_1655	1.41e-35	138.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42Z0I@68525|delta/epsilon subdivisions,2WUFE@28221|Deltaproteobacteria,2MN2T@213118|Desulfobacterales	28221|Deltaproteobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_308348_1	1238182.C882_4374	4.47e-56	189.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TT26@28211|Alphaproteobacteria,2JPYZ@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k59_308350_1	1109445.AGSX01000064_gene1455	2.94e-38	146.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,1Z0CN@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits	iorA	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
k59_464426_1	1267005.KB911257_gene683	1.15e-68	233.0	COG0433@1|root,COG1484@1|root,COG0433@2|Bacteria,COG1484@2|Bacteria,1P0I3@1224|Proteobacteria,2U0J8@28211|Alphaproteobacteria,3N9D3@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DUF853,DUF87
k59_855958_1	933262.AXAM01000019_gene1127	1.62e-34	118.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2MKYU@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_1209664_1	1452536.JARE01000050_gene2034	2.35e-36	136.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4FK3W@85023|Microbacteriaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_114454_1	1140.Synpcc7942_2531	5.22e-11	62.0	COG0264@1|root,COG0264@2|Bacteria,1G00T@1117|Cyanobacteria,1GYCT@1129|Synechococcus	1117|Cyanobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
k59_114454_2	1121405.dsmv_2175	4.3e-61	194.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2MIR4@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_1053293_1	765912.Thimo_1869	7.12e-50	172.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1WX1C@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_778016_1	109760.SPPG_05282T0	7.68e-64	215.0	COG0133@1|root,COG0159@1|root,KOG1395@2759|Eukaryota,KOG4175@2759|Eukaryota,38GS5@33154|Opisthokonta,3NUJ5@4751|Fungi	4751|Fungi	E	tryptophan synthase	-	-	4.2.1.20	ko:K01694,ko:K10882	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,ko03440,ko03460,map00260,map00400,map01100,map01110,map01130,map01230,map03440,map03460	M00023	R02722	RC00210,RC00700,RC02868	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	PALP,Trp_syntA
k59_347583_1	309807.SRU_1156	6.09e-48	174.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1FIMC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
k59_582358_1	648757.Rvan_2746	5.77e-66	215.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2TRMX@28211|Alphaproteobacteria,3N80X@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Peptidase M16 inactive domain	MA20_05660	-	-	ko:K07263,ko:K07623	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1090642_1	1121935.AQXX01000109_gene480	2.14e-131	404.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1XHSN@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_1053355_1	304371.MCP_2347	8.79e-71	235.0	COG3119@1|root,arCOG02791@2157|Archaea,2Y8G8@28890|Euryarchaeota,2NAEA@224756|Methanomicrobia	224756|Methanomicrobia	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_546705_1	1232410.KI421425_gene1552	1.26e-75	253.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42TDV@68525|delta/epsilon subdivisions,2WP7K@28221|Deltaproteobacteria,43UHJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_388088_1	1479237.JMLY01000001_gene1708	7.42e-64	219.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,464F1@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_659593_1	411467.BACCAP_00223	9.79e-43	149.0	COG2313@1|root,COG2313@2|Bacteria,1TR5J@1239|Firmicutes,247J8@186801|Clostridia,26852@186813|unclassified Clostridiales	186801|Clostridia	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
k59_778082_1	656519.Halsa_1877	7.7e-40	153.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3WA96@53433|Halanaerobiales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
k59_1001539_1	933262.AXAM01000013_gene1295	2.09e-21	85.5	COG1609@1|root,COG1609@2|Bacteria,1QW0S@1224|Proteobacteria,43BQP@68525|delta/epsilon subdivisions,2X71R@28221|Deltaproteobacteria,2MM94@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_97515_1	1117647.M5M_17745	3.68e-21	99.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1J4Z4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	lipoprotein	lpoA	GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
k59_488492_1	1304885.AUEY01000001_gene3189	6.29e-107	318.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42P2Q@68525|delta/epsilon subdivisions,2WKC2@28221|Deltaproteobacteria,2MJCP@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	hmcC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	NrfD
k59_958767_1	1121405.dsmv_3256	1.71e-57	194.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2MHPA@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
k59_449141_1	1121875.KB907546_gene2720	1.79e-74	241.0	28HMZ@1|root,2Z7WD@2|Bacteria,4P095@976|Bacteroidetes,1I89H@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_566735_1	1121405.dsmv_2547	4.41e-62	207.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2MIIC@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
k59_762409_1	261292.Nit79A3_1078	1.46e-37	144.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VHNB@28216|Betaproteobacteria,371VU@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_606470_1	519989.ECTPHS_06512	1.71e-11	63.9	COG1418@1|root,COG1418@2|Bacteria,1RH6M@1224|Proteobacteria,1S81F@1236|Gammaproteobacteria,1X2NE@135613|Chromatiales	135613|Chromatiales	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_606470_2	1304275.C41B8_00745	2.63e-33	125.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_918646_1	933262.AXAM01000016_gene188	6.4e-46	167.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MIKM@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k59_918653_1	384765.SIAM614_22527	1.19e-53	178.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2TU33@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	COG2998 ABC-type tungstate transport system, permease component	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
k59_918653_2	187272.Mlg_2739	6.52e-15	73.6	COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,1S5GB@1236|Gammaproteobacteria,1X0RK@135613|Chromatiales	135613|Chromatiales	P	ABC transporter	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
k59_1193915_1	391615.ABSJ01000022_gene272	2.79e-37	142.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1J4JE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
k59_293051_1	998088.B565_0050	2.35e-43	151.0	COG3329@1|root,COG3329@2|Bacteria,1N85P@1224|Proteobacteria,1RRX7@1236|Gammaproteobacteria,1Y4BX@135624|Aeromonadales	135624|Aeromonadales	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
k59_214678_1	1353531.AZNX01000003_gene2641	4.96e-52	176.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,4BA4C@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1040356_1	1229780.BN381_160029	1.45e-25	100.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
k59_1040356_2	742725.HMPREF9450_00513	5.97e-13	69.7	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,2FNVC@200643|Bacteroidia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_1075547_1	550540.Fbal_1295	1.85e-09	57.8	COG0834@1|root,COG1301@1|root,COG0834@2|Bacteria,COG1301@2|Bacteria,1P22C@1224|Proteobacteria,1RSGY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3,SDF
k59_1115454_1	1120983.KB894570_gene1444	5.11e-21	93.2	COG2230@1|root,COG2230@2|Bacteria,1N038@1224|Proteobacteria,2UDD9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	SAM dependent carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_7
k59_1115454_2	1123247.AUIJ01000025_gene740	8.3e-23	96.3	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
k59_958825_1	106370.Francci3_2318	7.5e-47	166.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
k59_1040379_1	765420.OSCT_1272	2.66e-79	245.0	COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,375RD@32061|Chloroflexia	32061|Chloroflexia	G	TIGRFAM 6-phosphogluconate dehydrogenase, decarboxylating	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
k59_413265_1	9593.ENSGGOP00000003636	1.38e-280	771.0	COG0088@1|root,KOG1475@2759|Eukaryota,38NDR@33154|Opisthokonta,3B9X9@33208|Metazoa,3CRNG@33213|Bilateria,484ZC@7711|Chordata,495JZ@7742|Vertebrata,3JDPT@40674|Mammalia,35H6D@314146|Euarchontoglires,4M6EX@9443|Primates,4N0YJ@9604|Hominidae	33208|Metazoa	J	structural constituent of ribosome	RPL4	GO:0000184,GO:0000956,GO:0001558,GO:0002181,GO:0003360,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005791,GO:0005829,GO:0005840,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007568,GO:0008097,GO:0008104,GO:0008150,GO:0008152,GO:0008340,GO:0008361,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009719,GO:0009892,GO:0009987,GO:0010033,GO:0010243,GO:0010259,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0012505,GO:0015031,GO:0015833,GO:0015934,GO:0016043,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0019843,GO:0022008,GO:0022603,GO:0022604,GO:0022625,GO:0022626,GO:0030016,GO:0030017,GO:0030154,GO:0030307,GO:0030516,GO:0031344,GO:0031346,GO:0031672,GO:0032501,GO:0032502,GO:0032535,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0040008,GO:0042221,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044449,GO:0044464,GO:0045047,GO:0045184,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045773,GO:0045927,GO:0046483,GO:0046700,GO:0046907,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048638,GO:0048639,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050770,GO:0050772,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051716,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0060322,GO:0061387,GO:0065007,GO:0065008,GO:0070727,GO:0070887,GO:0070972,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0090066,GO:0090150,GO:0090304,GO:0097159,GO:0099080,GO:0099081,GO:0099512,GO:0120035,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901698,GO:1901699,GO:1990904,GO:2000026	-	ko:K02930	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribos_L4_asso_C,Ribosomal_L4
k59_488588_1	1033802.SSPSH_002819	8.25e-44	160.0	COG0025@1|root,COG0025@2|Bacteria,1QTUE@1224|Proteobacteria,1T1HJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	nhaP	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,TrkA_N
k59_214751_1	574087.Acear_1266	1.1e-28	121.0	COG0714@1|root,COG1067@1|root,COG0714@2|Bacteria,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,3WAFP@53433|Halanaerobiales	186801|Clostridia	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_18057_1	335543.Sfum_3753	3.71e-12	66.6	COG0826@1|root,COG0826@2|Bacteria,1N4QJ@1224|Proteobacteria,42YJR@68525|delta/epsilon subdivisions,2WUQ1@28221|Deltaproteobacteria,2MR6V@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
k59_18057_2	204536.SULAZ_0587	2.45e-42	149.0	COG0406@1|root,COG0406@2|Bacteria,2G423@200783|Aquificae	200783|Aquificae	G	PFAM Phosphoglycerate mutase	pgmA	-	3.1.3.3	ko:K22305	ko00260,ko00680,ko01100,ko01120,ko01130,map00260,map00680,map01100,map01120,map01130	-	R00582	RC00017	ko00000,ko00001,ko01000	-	-	-	His_Phos_1
k59_1154441_1	1469245.JFBG01000019_gene1106	1.03e-173	504.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1WVYK@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_413315_1	1379270.AUXF01000001_gene2161	5.81e-48	175.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_449248_1	1101191.KI912577_gene3938	3.48e-08	57.4	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,1JS22@119045|Methylobacteriaceae	28211|Alphaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
k59_449248_2	1265503.KB905170_gene110	3.36e-16	77.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,2Q5NU@267889|Colwelliaceae	1236|Gammaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iEC042_1314.EC042_2346,iECUMN_1333.ECUMN_2446	Anticodon_1,tRNA-synt_1g,tRNA_bind
k59_1236157_2	1221537.B807_235	3.29e-10	63.9	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,3F4C6@33958|Lactobacillaceae	91061|Bacilli	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_958897_1	1304885.AUEY01000028_gene2790	1.98e-87	266.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,2MHNK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
k59_413338_1	1121921.KB898712_gene2233	2.03e-33	132.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,2PN33@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	NU	Bacterial type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
k59_214814_1	768706.Desor_0837	4e-07	57.4	COG2006@1|root,COG2006@2|Bacteria,1TRYQ@1239|Firmicutes,24966@186801|Clostridia,262RM@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
k59_1194013_1	9601.ENSPPYP00000023136	1.04e-213	600.0	KOG0749@1|root,KOG0752@1|root,KOG0749@2759|Eukaryota,KOG0752@2759|Eukaryota,38B82@33154|Opisthokonta,3B9K3@33208|Metazoa,3CTAF@33213|Bilateria,482KI@7711|Chordata,48WR1@7742|Vertebrata,3JCY0@40674|Mammalia,35B8V@314146|Euarchontoglires,4M8XF@9443|Primates,4MYUI@9604|Hominidae	33208|Metazoa	C	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	SLC25A5	GO:0000295,GO:0002791,GO:0003674,GO:0005215,GO:0005345,GO:0005346,GO:0005347,GO:0005471,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005819,GO:0005856,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006839,GO:0006855,GO:0006862,GO:0006863,GO:0006996,GO:0007005,GO:0007006,GO:0008150,GO:0008284,GO:0008509,GO:0008514,GO:0009295,GO:0009966,GO:0009968,GO:0009987,GO:0010639,GO:0010646,GO:0010648,GO:0010817,GO:0010821,GO:0010823,GO:0010941,GO:0015075,GO:0015205,GO:0015207,GO:0015215,GO:0015216,GO:0015217,GO:0015238,GO:0015291,GO:0015297,GO:0015301,GO:0015605,GO:0015630,GO:0015711,GO:0015748,GO:0015851,GO:0015853,GO:0015865,GO:0015866,GO:0015867,GO:0015868,GO:0015893,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0016043,GO:0019866,GO:0019899,GO:0022804,GO:0022857,GO:0023051,GO:0023057,GO:0031090,GO:0031224,GO:0031226,GO:0031625,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0034220,GO:0042127,GO:0042221,GO:0042493,GO:0042645,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0046883,GO:0046902,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050708,GO:0050789,GO:0050794,GO:0050796,GO:0050896,GO:0051046,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051179,GO:0051223,GO:0051234,GO:0051503,GO:0055085,GO:0060548,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070201,GO:0071702,GO:0071705,GO:0071817,GO:0071840,GO:0071944,GO:0072530,GO:0090087,GO:0090276,GO:0090559,GO:0098656,GO:0099516,GO:1901028,GO:1901029,GO:1901264,GO:1901505,GO:1901679,GO:1903530,GO:1904823,GO:2001233,GO:2001234	-	ko:K05863	ko04020,ko04022,ko04217,ko04218,ko05012,ko05016,ko05166,map04020,map04022,map04217,map04218,map05012,map05016,map05166	-	-	-	ko00000,ko00001,ko02000,ko03029	2.A.29.1	-	-	Mito_carr
k59_175712_1	56780.SYN_00568	1.48e-70	233.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_293170_1	1229205.BUPH_05535	8.35e-66	210.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VQF1@28216|Betaproteobacteria,1K10X@119060|Burkholderiaceae	28216|Betaproteobacteria	L	transposase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_18105_1	768671.ThimaDRAFT_4320	1.77e-78	249.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,1WXIE@135613|Chromatiales	135613|Chromatiales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
k59_644933_1	1123073.KB899241_gene2341	6.27e-18	87.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,1T1QG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_723937_2	634498.mru_0897	8.2e-20	87.8	COG0500@1|root,arCOG06507@2157|Archaea,2Y4ZZ@28890|Euryarchaeota,23PUV@183925|Methanobacteria	2157|Archaea	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k59_918786_1	1033802.SSPSH_003692	7.07e-88	266.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_413404_1	1408473.JHXO01000009_gene3319	3.45e-49	164.0	COG1489@1|root,COG1489@2|Bacteria,4NKJC@976|Bacteroidetes,2FWK1@200643|Bacteroidia	976|Bacteroidetes	S	Sugar fermentation stimulation protein	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
k59_214899_1	941449.dsx2_0363	1.42e-83	273.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2M9PX@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
k59_723989_1	1348114.OM33_08825	1.24e-17	82.8	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,1RMHS@1236|Gammaproteobacteria,2Q0BM@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2500,iBWG_1329.BWG_2264,iECDH10B_1368.ECDH10B_2666,iECDH1ME8569_1439.ECDH1ME8569_2426,iEcDH1_1363.EcDH1_1169,iJO1366.b2500,iJR904.b2500,iY75_1357.Y75_RS13050	Formyl_trans_N
k59_959008_1	9597.XP_003807008.1	3.8e-129	380.0	KOG2945@1|root,KOG2945@2759|Eukaryota,38FFW@33154|Opisthokonta,3BEJZ@33208|Metazoa,3CXCU@33213|Bilateria,48A62@7711|Chordata,48ZZU@7742|Vertebrata,3J9JB@40674|Mammalia,35HFV@314146|Euarchontoglires,4MG6X@9443|Primates,4MTUU@9604|Hominidae	33208|Metazoa	S	SERPINE1 mRNA binding protein 1	SERBP1	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005700,GO:0005701,GO:0005703,GO:0005737,GO:0005829,GO:0006325,GO:0006355,GO:0006464,GO:0006479,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008213,GO:0009889,GO:0009892,GO:0009894,GO:0009987,GO:0010369,GO:0010468,GO:0010556,GO:0010605,GO:0010608,GO:0010629,GO:0016043,GO:0016246,GO:0016441,GO:0016442,GO:0016458,GO:0016569,GO:0016570,GO:0016571,GO:0018022,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0031047,GO:0031323,GO:0031326,GO:0031329,GO:0031332,GO:0031935,GO:0032259,GO:0032991,GO:0033043,GO:0033044,GO:0034968,GO:0035194,GO:0036211,GO:0040029,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043414,GO:0043487,GO:0043488,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0051276,GO:0051567,GO:0060255,GO:0060968,GO:0061013,GO:0061647,GO:0065007,GO:0065008,GO:0070828,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0098687,GO:1901363,GO:1901564,GO:1902275,GO:1903311,GO:1903506,GO:1990904,GO:2000112,GO:2001141	-	ko:K13199	-	-	-	-	ko00000,ko03041	-	-	-	HABP4_PAI-RBP1,IHABP4_N
k59_293265_1	335543.Sfum_0650	9.5e-46	159.0	COG0589@1|root,COG0589@2|Bacteria,1REA3@1224|Proteobacteria,42RXY@68525|delta/epsilon subdivisions,2WNM6@28221|Deltaproteobacteria,2MSDJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_449369_1	589865.DaAHT2_0736	1.06e-131	399.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MHRD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_488740_1	9606.ENSP00000322439	4.3e-202	567.0	COG0050@1|root,KOG0460@2759|Eukaryota,38BHM@33154|Opisthokonta,3BE5J@33208|Metazoa,3CUKG@33213|Bilateria,487W9@7711|Chordata,48YZ2@7742|Vertebrata,3J4W4@40674|Mammalia,35MQV@314146|Euarchontoglires,4M6FQ@9443|Primates,4MWPX@9604|Hominidae	33208|Metazoa	J	Elongation factor Tu C-terminal domain	TUFM	GO:0000278,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006996,GO:0007030,GO:0007049,GO:0008135,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009059,GO:0009295,GO:0009636,GO:0009987,GO:0010033,GO:0010256,GO:0010467,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0034641,GO:0034645,GO:0042221,GO:0042493,GO:0042645,GO:0043043,GO:0043170,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045471,GO:0046677,GO:0050896,GO:0070013,GO:0071704,GO:0071840,GO:0097159,GO:0097305,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901700	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_253912_1	1121918.ARWE01000001_gene802	1.01e-67	222.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DNA recombination protein RmuC	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
k59_645020_1	1198452.Jab_2c30310	2.2e-17	83.6	COG0642@1|root,COG0715@1|root,COG5002@1|root,COG0715@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,472D0@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
k59_645020_2	869213.JCM21142_93894	4.14e-13	70.5	COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,47JXG@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_175864_1	1499967.BAYZ01000009_gene5391	2.81e-104	325.0	COG2766@1|root,COG2766@2|Bacteria	2|Bacteria	T	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_PrkA,PrkA
k59_531767_1	439481.Aboo_0301	2.55e-07	52.0	COG1013@1|root,arCOG01601@2157|Archaea,2XT3E@28890|Euryarchaeota,3F2JH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	vorB	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_531767_2	1485545.JQLW01000010_gene1673	1.02e-07	53.5	COG0759@1|root,COG0759@2|Bacteria	2|Bacteria	M	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
k59_491383_1	1397666.RS24_00329	7.51e-58	194.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
k59_416980_1	438753.AZC_2869	1.48e-26	107.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U4RM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_1118272_2	177437.HRM2_12680	3.7e-20	92.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2MHYY@213118|Desulfobacterales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
k59_218502_1	1123401.JHYQ01000007_gene542	4.1e-111	345.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria,461JN@72273|Thiotrichales	72273|Thiotrichales	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_687372_1	1397527.Q670_01595	5.88e-48	166.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XIGF@135619|Oceanospirillales	135619|Oceanospirillales	E	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_687372_2	1385935.N836_22495	2.1e-88	270.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_765246_1	1167006.UWK_01323	4.25e-176	502.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1005288_1	335543.Sfum_1936	3.64e-85	265.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2MRBS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_1239594_1	1528106.JRJE01000008_gene1588	3.35e-40	141.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2TUHX@28211|Alphaproteobacteria,2JQKM@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome C1 family	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
k59_531858_1	946483.Cenrod_2573	2.24e-43	154.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,4A9QE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_531858_2	998088.B565_0284	0.000479	42.7	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1Y4G3@135624|Aeromonadales	135624|Aeromonadales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
k59_178105_1	1121423.JONT01000004_gene1669	8.2e-21	97.8	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,260UH@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K10681	ko02020,map02020	M00468	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_218542_1	1332071.L581_3718	1.44e-54	187.0	COG0043@1|root,COG0043@2|Bacteria,1PZMY@1224|Proteobacteria,1S199@1236|Gammaproteobacteria,404PN@613|Serratia	1236|Gammaproteobacteria	H	Catalyzes the reversible decarboxylation of aromatic carboxylic acids	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
k59_961780_1	1968.JOEV01000005_gene6185	3.35e-27	110.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_451972_1	196367.JNFG01000209_gene256	3.16e-32	129.0	COG5421@1|root,COG5421@2|Bacteria,1R25F@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4277
k59_417064_1	1229172.JQFA01000002_gene3055	1.01e-27	106.0	COG2343@1|root,COG2343@2|Bacteria,1G50P@1117|Cyanobacteria,1HAMP@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG2343 conserved	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
k59_417064_2	1118054.CAGW01000062_gene2215	6.22e-07	51.6	COG1986@1|root,COG1986@2|Bacteria,1V6CG@1239|Firmicutes,4HIVY@91061|Bacilli	91061|Bacilli	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	yjjX	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
k59_256658_1	1523503.JPMY01000012_gene3350	3.19e-16	78.2	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A)	lpxL	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iEC042_1314.EC042_2597,iSF_1195.SF1061,iS_1188.S1138,iYL1228.KPN_01068	Lip_A_acyltrans
k59_256658_2	1198232.CYCME_2436	3.71e-10	62.4	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_1042719_1	1301098.PKB_2032	4.89e-31	122.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
k59_875123_1	247633.GP2143_01410	1.95e-47	157.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1J5ZY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_757544_1	1167006.UWK_02738	3.06e-59	192.0	COG1427@1|root,COG1427@2|Bacteria,1RCS0@1224|Proteobacteria,42SPW@68525|delta/epsilon subdivisions,2WP7F@28221|Deltaproteobacteria,2MIFZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_366356_1	768671.ThimaDRAFT_2793	1.11e-109	329.0	COG3039@1|root,COG3039@2|Bacteria,1P2FY@1224|Proteobacteria,1SRZF@1236|Gammaproteobacteria,1X1EC@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_757570_1	159087.Daro_2040	1.53e-09	57.4	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2VSCN@28216|Betaproteobacteria,2KX28@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
k59_757570_2	987059.RBXJA2T_12477	3.26e-29	116.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,1KJ4K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
k59_248600_1	1499967.BAYZ01000048_gene2702	1.04e-83	255.0	COG3752@1|root,COG3752@2|Bacteria,2NR3R@2323|unclassified Bacteria	2|Bacteria	S	3-oxo-5-alpha-steroid 4-dehydrogenase	yfhH	-	1.3.1.22	ko:K12343	ko00140,map00140	-	R02208,R02497,R08954,R10242	RC00145	ko00000,ko00001,ko01000	-	-	-	DUF1295
k59_209147_1	1328313.DS2_03775	3.47e-58	202.0	COG0457@1|root,COG1462@1|root,COG0457@2|Bacteria,COG1462@2|Bacteria,1N4V4@1224|Proteobacteria,1SMDT@1236|Gammaproteobacteria,46AGV@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
k59_719072_1	1120953.AUBH01000006_gene2608	2.58e-35	135.0	COG5309@1|root,COG5309@2|Bacteria,1Q5JR@1224|Proteobacteria,1SJJ9@1236|Gammaproteobacteria	2|Bacteria	G	Glycosyl hydrolases family 17	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_17
k59_836025_1	880072.Desac_2367	1.3e-77	254.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_953679_1	880072.Desac_0850	0.000163	47.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,2MQBM@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1229967_1	1279017.AQYJ01000027_gene1618	3.73e-56	194.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RRN4@1236|Gammaproteobacteria,4674P@72275|Alteromonadaceae	1236|Gammaproteobacteria	EU	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9,Peptidase_S9_N
k59_1229967_2	1163408.UU9_10337	1.82e-20	92.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria,1X4TK@135614|Xanthomonadales	135614|Xanthomonadales	S	2-methylcitrate dehydratase	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
k59_995064_1	1049564.TevJSym_ao00750	2.2e-127	370.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1J52U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	COG1077 Actin-like ATPase involved in cell morphogenesis	mreB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
k59_719115_1	1254432.SCE1572_12045	2.04e-39	140.0	2EQU0@1|root,33IDQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1070903_1	1174504.AJTN02000221_gene1137	6.85e-35	130.0	COG2220@1|root,COG2220@2|Bacteria,1TRRP@1239|Firmicutes,4HDF8@91061|Bacilli,1ZC0M@1386|Bacillus	91061|Bacilli	S	Beta-lactamase superfamily domain	romA	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_248669_1	765912.Thimo_0681	5e-64	207.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1WXGA@135613|Chromatiales	135613|Chromatiales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_248669_2	95619.PM1_0211685	1.26e-13	69.7	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iE2348C_1286.E2348C_4372,iJN746.PP_4187	Pyr_redox_2,Pyr_redox_dim
k59_561901_1	323097.Nham_1921	2.31e-60	197.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,3JSFD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS,STAS_2
k59_561901_2	395964.KE386496_gene1437	1.03e-10	60.8	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,3NAWW@45404|Beijerinckiaceae	28211|Alphaproteobacteria	Q	ATPases associated with a variety of cellular activities	yrbF	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
k59_719150_1	525897.Dbac_2336	1.31e-21	90.5	COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,42MVF@68525|delta/epsilon subdivisions,2WN3G@28221|Deltaproteobacteria,2M8G0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_719150_2	1121413.JMKT01000009_gene2202	1.19e-39	140.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M6H@68525|delta/epsilon subdivisions,2WNDN@28221|Deltaproteobacteria,2M82Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin	-	-	-	ko:K04014,ko:K08358	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Fer4_11,Fer4_3,Fer4_4
k59_836118_2	472759.Nhal_1494	1.26e-41	144.0	COG0224@1|root,COG0224@2|Bacteria,1QUME@1224|Proteobacteria,1S2EG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
k59_875271_1	1380394.JADL01000004_gene5920	2.75e-59	200.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TSME@28211|Alphaproteobacteria,2JQW6@204441|Rhodospirillales	204441|Rhodospirillales	E	Gamma-glutamyltranspeptidase	-	-	-	-	-	-	-	-	-	-	-	-	G_glu_transpept
k59_995153_1	383407.XOC_2903	9.63e-05	44.7	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,1X7PF@135614|Xanthomonadales	135614|Xanthomonadales	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
k59_248700_1	283942.IL2214	8.25e-87	275.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,2QFPW@267893|Idiomarinaceae	1236|Gammaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,iYL1228.KPN_02799,ic_1306.c2990	Transket_pyr,Transketolase_C,Transketolase_N
k59_52373_1	1121405.dsmv_1952	1.7e-47	170.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,2MJ25@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
k59_601490_1	247633.GP2143_04173	1.04e-71	234.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_251603_2	1232437.KL662061_gene4181	1.7e-14	70.1	COG0745@1|root,COG0789@1|root,COG0745@2|Bacteria,COG0789@2|Bacteria,1RD9E@1224|Proteobacteria,42PTZ@68525|delta/epsilon subdivisions,2WKZI@28221|Deltaproteobacteria,2MHNV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
k59_1113398_1	438753.AZC_0338	1.97e-57	200.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,3EYP2@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
k59_329578_1	1300345.LF41_2593	6.57e-30	121.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria,1X903@135614|Xanthomonadales	135614|Xanthomonadales	S	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
k59_212269_1	1267005.KB911255_gene2392	6.84e-80	258.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,3N62W@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1233979_1	1454004.AW11_01609	4.17e-39	138.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,1KPPC@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_1233979_2	305700.B447_05243	8e-05	43.9	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,2KV5P@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
k59_604436_1	105559.Nwat_0402	1.49e-48	168.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1WW2I@135613|Chromatiales	135613|Chromatiales	HL	Thiamine monophosphate synthase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,NUDIX_4,TMP-TENI
k59_956692_1	929556.Solca_1368	1.78e-40	150.0	COG0624@1|root,COG0624@2|Bacteria,4NEHJ@976|Bacteroidetes,1IS2Y@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_329598_1	1173023.KE650771_gene1475	1.23e-07	53.9	COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,1JJWX@1189|Stigonemataceae	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
k59_329598_2	95619.PM1_0220750	5.45e-37	129.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
k59_604453_1	414684.RC1_1262	2.93e-84	277.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,2JPMN@204441|Rhodospirillales	204441|Rhodospirillales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_212289_1	9606.ENSP00000247470	1.15e-130	371.0	2CYBZ@1|root,2S3G5@2759|Eukaryota,3A2SM@33154|Opisthokonta,3BR32@33208|Metazoa,3D4H5@33213|Bilateria,487QF@7711|Chordata,4990A@7742|Vertebrata,3JBGQ@40674|Mammalia,35DDG@314146|Euarchontoglires,4M60K@9443|Primates,4N4PP@9604|Hominidae	33208|Metazoa	K	PAAD/DAPIN/Pyrin domain	PYCARD	GO:0000323,GO:0001773,GO:0001775,GO:0001816,GO:0001817,GO:0001818,GO:0001819,GO:0001932,GO:0001933,GO:0001934,GO:0001959,GO:0002020,GO:0002218,GO:0002230,GO:0002237,GO:0002252,GO:0002253,GO:0002263,GO:0002274,GO:0002275,GO:0002277,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002577,GO:0002579,GO:0002580,GO:0002582,GO:0002583,GO:0002585,GO:0002586,GO:0002588,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002694,GO:0002696,GO:0002697,GO:0002791,GO:0002793,GO:0002819,GO:0002821,GO:0002831,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0005102,GO:0005126,GO:0005138,GO:0005488,GO:0005515,GO:0005523,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005829,GO:0006355,GO:0006469,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006897,GO:0006907,GO:0006915,GO:0006919,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006974,GO:0007154,GO:0007165,GO:0007166,GO:0008047,GO:0008064,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008234,GO:0008284,GO:0008385,GO:0008630,GO:0008656,GO:0009605,GO:0009607,GO:0009615,GO:0009617,GO:0009889,GO:0009892,GO:0009893,GO:0009894,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010506,GO:0010556,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010638,GO:0010646,GO:0010647,GO:0010648,GO:0010803,GO:0010821,GO:0010822,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0012505,GO:0016043,GO:0016192,GO:0016485,GO:0016504,GO:0016505,GO:0016787,GO:0017022,GO:0017024,GO:0019219,GO:0019220,GO:0019221,GO:0019222,GO:0019538,GO:0019899,GO:0019904,GO:0022407,GO:0022409,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030100,GO:0030141,GO:0030155,GO:0030162,GO:0030234,GO:0030334,GO:0030335,GO:0030832,GO:0030833,GO:0030838,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031329,GO:0031334,GO:0031347,GO:0031349,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031638,GO:0031647,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032088,GO:0032090,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032271,GO:0032273,GO:0032479,GO:0032480,GO:0032496,GO:0032501,GO:0032535,GO:0032611,GO:0032612,GO:0032642,GO:0032648,GO:0032649,GO:0032651,GO:0032652,GO:0032653,GO:0032675,GO:0032677,GO:0032680,GO:0032688,GO:0032722,GO:0032729,GO:0032731,GO:0032732,GO:0032733,GO:0032755,GO:0032757,GO:0032760,GO:0032872,GO:0032874,GO:0032879,GO:0032880,GO:0032940,GO:0032944,GO:0032946,GO:0032956,GO:0032970,GO:0032991,GO:0033043,GO:0033209,GO:0033554,GO:0033612,GO:0033673,GO:0033993,GO:0034097,GO:0034612,GO:0034774,GO:0035556,GO:0035578,GO:0036230,GO:0036477,GO:0040012,GO:0040017,GO:0042102,GO:0042104,GO:0042119,GO:0042127,GO:0042129,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042582,GO:0042742,GO:0042771,GO:0042802,GO:0042803,GO:0042981,GO:0043025,GO:0043028,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043086,GO:0043087,GO:0043122,GO:0043124,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043280,GO:0043281,GO:0043299,GO:0043312,GO:0043408,GO:0043410,GO:0043433,GO:0043549,GO:0043900,GO:0044087,GO:0044089,GO:0044092,GO:0044093,GO:0044238,GO:0044297,GO:0044325,GO:0044351,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044437,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045055,GO:0045088,GO:0045089,GO:0045321,GO:0045785,GO:0045807,GO:0045859,GO:0045862,GO:0045936,GO:0045937,GO:0046006,GO:0046328,GO:0046330,GO:0046903,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050670,GO:0050671,GO:0050688,GO:0050691,GO:0050704,GO:0050706,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050716,GO:0050718,GO:0050727,GO:0050764,GO:0050766,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050829,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051090,GO:0051091,GO:0051092,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051251,GO:0051252,GO:0051270,GO:0051272,GO:0051336,GO:0051338,GO:0051345,GO:0051348,GO:0051493,GO:0051495,GO:0051604,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0060627,GO:0060759,GO:0061134,GO:0061695,GO:0061702,GO:0065007,GO:0065008,GO:0065009,GO:0070011,GO:0070013,GO:0070201,GO:0070302,GO:0070304,GO:0070372,GO:0070374,GO:0070555,GO:0070663,GO:0070665,GO:0070696,GO:0070700,GO:0070851,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071345,GO:0071347,GO:0071356,GO:0071396,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0072331,GO:0072332,GO:0072557,GO:0072558,GO:0072559,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0090087,GO:0090196,GO:0090197,GO:0090199,GO:0090200,GO:0097153,GO:0097169,GO:0097190,GO:0097193,GO:0097202,GO:0097458,GO:0097708,GO:0098542,GO:0098657,GO:0098772,GO:0099503,GO:0110053,GO:0140096,GO:1901564,GO:1901700,GO:1901701,GO:1902494,GO:1902531,GO:1902532,GO:1902533,GO:1902554,GO:1902903,GO:1902905,GO:1902911,GO:1903037,GO:1903039,GO:1903506,GO:1903530,GO:1903532,GO:1903555,GO:1903557,GO:1904951,GO:1990234,GO:2000112,GO:2000116,GO:2000145,GO:2000147,GO:2000401,GO:2000403,GO:2000404,GO:2000406,GO:2000482,GO:2000484,GO:2000778,GO:2001056,GO:2001141,GO:2001179,GO:2001181,GO:2001233,GO:2001235,GO:2001236,GO:2001238,GO:2001242	-	ko:K12799	ko04217,ko04621,ko04623,ko05132,ko05133,ko05134,ko05164,map04217,map04621,map04623,map05132,map05133,map05134,map05164	-	-	-	ko00000,ko00001	-	-	-	CARD,PYRIN
k59_916781_1	1123279.ATUS01000003_gene379	3.43e-69	218.0	2BVTQ@1|root,2Z7J9@2|Bacteria,1P01Z@1224|Proteobacteria,1RNNB@1236|Gammaproteobacteria,1J5GW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2797)	LA2027	-	-	-	-	-	-	-	-	-	-	-	DUF2797
k59_290967_1	1382359.JIAL01000001_gene334	1.62e-08	57.0	COG0680@1|root,COG0680@2|Bacteria,3Y9G5@57723|Acidobacteria,2JNUV@204432|Acidobacteriia	204432|Acidobacteriia	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
k59_212314_1	1121935.AQXX01000110_gene5509	9.91e-28	107.0	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,1RMHT@1236|Gammaproteobacteria,1XHGH@135619|Oceanospirillales	135619|Oceanospirillales	M	aspartate racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
k59_133619_1	1123070.KB899252_gene925	1.32e-62	204.0	COG3659@1|root,COG3659@2|Bacteria,46U4Z@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
k59_54978_1	1121918.ARWE01000001_gene211	1.17e-116	355.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WUR2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
k59_916814_1	1260251.SPISAL_02165	4.73e-49	174.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1WWCN@135613|Chromatiales	135613|Chromatiales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
k59_1073766_1	1298593.TOL_2140	1.65e-09	63.2	COG0810@1|root,COG0810@2|Bacteria,1RKRA@1224|Proteobacteria,1S52T@1236|Gammaproteobacteria,1XK9J@135619|Oceanospirillales	135619|Oceanospirillales	M	Tol-Pal system TolA	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
k59_1073766_2	1117318.PRUB_00365	7.13e-14	73.2	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,2Q1NJ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
k59_1234095_1	1385935.N836_33540	3.45e-46	170.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,1G03V@1117|Cyanobacteria,1H7B2@1150|Oscillatoriales	1117|Cyanobacteria	CE	PFAM peptidase M1, membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,HEAT_2,Peptidase_M1
k59_369438_1	1122604.JONR01000006_gene2654	4.12e-84	266.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1X48I@135614|Xanthomonadales	135614|Xanthomonadales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k59_721984_1	1121861.KB899914_gene1998	1.31e-15	77.4	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2TS1C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
k59_721984_2	1502851.FG93_02731	1.63e-20	90.9	COG0747@1|root,COG0747@2|Bacteria,1MWBH@1224|Proteobacteria,2TXJS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_133662_1	472759.Nhal_0455	9.81e-95	298.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1WW1J@135613|Chromatiales	135613|Chromatiales	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_799302_1	933262.AXAM01000094_gene2192	3.18e-101	308.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,42M60@68525|delta/epsilon subdivisions,2WITJ@28221|Deltaproteobacteria,2MHXY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	dsrK	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_329696_1	1121438.JNJA01000002_gene3598	1.04e-82	249.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2WJMH@28221|Deltaproteobacteria,2M84J@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
k59_410716_1	472759.Nhal_1456	7.96e-79	250.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1WWTW@135613|Chromatiales	135613|Chromatiales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_999144_1	391587.KAOT1_14757	7.89e-116	358.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,1HY0G@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase family M3	-	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_839132_1	706587.Desti_4204	1.16e-97	296.0	COG0467@1|root,COG1476@1|root,COG1917@1|root,COG0467@2|Bacteria,COG1476@2|Bacteria,COG1917@2|Bacteria,1PE60@1224|Proteobacteria,42NFD@68525|delta/epsilon subdivisions,2WK1C@28221|Deltaproteobacteria,2MQST@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
k59_1113554_1	1009370.ALO_15747	1.41e-09	64.7	COG4775@1|root,COG4775@2|Bacteria,1UMDS@1239|Firmicutes,4H27F@909932|Negativicutes	909932|Negativicutes	M	Outer membrane protein, OMP85 family	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_447389_1	1121939.L861_19660	4.17e-49	169.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RPVQ@1236|Gammaproteobacteria,1XNWY@135619|Oceanospirillales	135619|Oceanospirillales	I	Poly-beta-hydroxybutyrate polymerase N terminal	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PHBC_N,PhaC_N
k59_956852_1	1192034.CAP_4443	9.61e-51	176.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1PFBF@1224|Proteobacteria,42RAR@68525|delta/epsilon subdivisions,2WN52@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Protein phosphatase 2C domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,SpoIIE
k59_999187_1	880072.Desac_1537	3.09e-47	167.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,2MQ55@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_173024_1	9606.ENSP00000432218	1.52e-135	384.0	2D9GX@1|root,2TEHQ@2759|Eukaryota,3AQRF@33154|Opisthokonta,3C2YA@33208|Metazoa,3DIYW@33213|Bilateria,48GJZ@7711|Chordata,49DDN@7742|Vertebrata,3JIAV@40674|Mammalia,35T8B@314146|Euarchontoglires,4MMX3@9443|Primates,4MZDB@9604|Hominidae	33208|Metazoa	T	Interleukin 32	IL32	GO:0002376,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006952,GO:0006955,GO:0007154,GO:0007155,GO:0007165,GO:0007166,GO:0008150,GO:0009987,GO:0010033,GO:0019221,GO:0022610,GO:0023052,GO:0034097,GO:0042221,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071310,GO:0071345	-	-	-	-	-	-	-	-	-	-	IL32
k59_133729_1	998674.ATTE01000001_gene3275	2.84e-22	98.6	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,1RSF8@1236|Gammaproteobacteria,46155@72273|Thiotrichales	72273|Thiotrichales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1113572_1	391615.ABSJ01000035_gene1009	2.8e-90	294.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1J4ZQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_956870_1	1123360.thalar_02890	4.45e-31	114.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
k59_1152552_1	1123377.AUIV01000002_gene1105	2.31e-31	120.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1X3KJ@135614|Xanthomonadales	135614|Xanthomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_682599_1	338966.Ppro_3708	9.93e-50	171.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_173084_1	247634.GPB2148_1636	1.11e-23	95.5	2DDDN@1|root,32U19@2|Bacteria,1N1UD@1224|Proteobacteria,1SAT8@1236|Gammaproteobacteria,1J9YU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_173084_2	236097.ADG881_601	6.32e-10	58.9	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1XHJP@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
k59_291157_1	1411685.U062_02071	4.35e-43	159.0	COG1948@1|root,COG4880@2|Bacteria,1PQKR@1224|Proteobacteria,1RVSQ@1236|Gammaproteobacteria,1J807@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
k59_212500_1	933262.AXAM01000020_gene26	4.8e-42	158.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2MITA@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
k59_526191_2	1163408.UU9_03577	8.39e-14	73.9	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1X38B@135614|Xanthomonadales	135614|Xanthomonadales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_212515_1	1038860.AXAP01000122_gene3283	1.18e-128	370.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1MW8A@1224|Proteobacteria,2UQQJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32,HTH_33
k59_212516_1	1168034.FH5T_20580	5.94e-16	83.2	COG2207@1|root,COG5616@1|root,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_916989_2	672.VV93_v1c21460	0.000451	43.9	COG5662@1|root,COG5662@2|Bacteria,1RJ4M@1224|Proteobacteria,1S23M@1236|Gammaproteobacteria,1XURI@135623|Vibrionales	135623|Vibrionales	K	Protein of unknown function (DUF3379)	EBIG1770	-	-	-	-	-	-	-	-	-	-	-	DUF3379
k59_1073912_1	236097.ADG881_1304	2.71e-57	197.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1XI2V@135619|Oceanospirillales	135619|Oceanospirillales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_212531_1	267608.RSp1637	6.66e-53	180.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2VJ85@28216|Betaproteobacteria,1K347@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcription regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
k59_16289_1	395964.KE386496_gene759	2.91e-41	150.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2TRCD@28211|Alphaproteobacteria,3NAB6@45404|Beijerinckiaceae	28211|Alphaproteobacteria	F	Phosphohydrolase-associated domain	dgt	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_839249_1	1232410.KI421415_gene3112	1.68e-07	57.8	COG1102@1|root,COG2823@1|root,COG1102@2|Bacteria,COG2823@2|Bacteria,1PKHZ@1224|Proteobacteria,43EGQ@68525|delta/epsilon subdivisions,2X25G@28221|Deltaproteobacteria,43UDU@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	BON,Cytidylate_kin2
k59_410927_1	1121448.DGI_2993	1.79e-25	106.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1PFBF@1224|Proteobacteria,42RAR@68525|delta/epsilon subdivisions,2WN52@28221|Deltaproteobacteria,2MAC7@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,SpoIIE
k59_1123051_1	1121441.AUCX01000036_gene22	1.01e-17	87.4	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria,2M9SF@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_770053_1	493475.GARC_2568	7.85e-24	107.0	COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,465RT@72275|Alteromonadaceae	1236|Gammaproteobacteria	MU	COG1538 Outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_496120_2	680646.RMDY18_07090	7.07e-05	45.1	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,1W8HP@1268|Micrococcaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_1162058_1	335283.Neut_0545	5.16e-32	121.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,2VHCH@28216|Betaproteobacteria,371Q7@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
k59_692059_1	1535422.ND16A_1612	3.27e-86	270.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RPAA@1236|Gammaproteobacteria,2Q7GC@267889|Colwelliaceae	1236|Gammaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_8
k59_423363_1	861299.J421_2666	8.14e-58	193.0	COG0508@1|root,COG0508@2|Bacteria,1ZSYJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_1123108_1	61853.ENSNLEP00000001135	5.02e-118	352.0	KOG1190@1|root,KOG1190@2759|Eukaryota,38H7H@33154|Opisthokonta,3B9RH@33208|Metazoa,3CRKU@33213|Bilateria,483UE@7711|Chordata,48VI4@7742|Vertebrata,3J3SY@40674|Mammalia,35NGR@314146|Euarchontoglires,4MCIA@9443|Primates	33208|Metazoa	A	Polypyrimidine tract binding protein 1	PTBP1	GO:0000003,GO:0000014,GO:0000226,GO:0000375,GO:0000377,GO:0000381,GO:0000398,GO:0000900,GO:0000956,GO:0001067,GO:0001069,GO:0002009,GO:0002165,GO:0002791,GO:0002793,GO:0003006,GO:0003205,GO:0003231,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0003727,GO:0003729,GO:0003730,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0006139,GO:0006259,GO:0006355,GO:0006357,GO:0006396,GO:0006397,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007291,GO:0007292,GO:0007308,GO:0007309,GO:0007319,GO:0007349,GO:0007389,GO:0007399,GO:0007444,GO:0007472,GO:0007476,GO:0007507,GO:0007552,GO:0007560,GO:0008103,GO:0008150,GO:0008152,GO:0008187,GO:0008380,GO:0008543,GO:0008586,GO:0008587,GO:0009056,GO:0009057,GO:0009653,GO:0009719,GO:0009791,GO:0009798,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0009994,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010638,GO:0010646,GO:0010647,GO:0010720,GO:0010817,GO:0010975,GO:0010976,GO:0016032,GO:0016043,GO:0016070,GO:0016071,GO:0016325,GO:0016787,GO:0016788,GO:0017148,GO:0019080,GO:0019081,GO:0019219,GO:0019220,GO:0019222,GO:0019439,GO:0019953,GO:0021700,GO:0022008,GO:0022412,GO:0022414,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030371,GO:0030951,GO:0030952,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032024,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033119,GO:0034248,GO:0034249,GO:0034250,GO:0034641,GO:0034655,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0036002,GO:0042221,GO:0042995,GO:0043005,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043484,GO:0043487,GO:0043488,GO:0043489,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044306,GO:0044344,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044463,GO:0044464,GO:0044703,GO:0045182,GO:0045595,GO:0045596,GO:0045597,GO:0045664,GO:0045666,GO:0045727,GO:0045893,GO:0045934,GO:0045935,GO:0045937,GO:0045944,GO:0046011,GO:0046483,GO:0046700,GO:0046883,GO:0046887,GO:0048024,GO:0048025,GO:0048232,GO:0048255,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048563,GO:0048569,GO:0048583,GO:0048584,GO:0048599,GO:0048609,GO:0048646,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0050684,GO:0050686,GO:0050708,GO:0050714,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050796,GO:0050848,GO:0050850,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051147,GO:0051148,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0051716,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0060429,GO:0060562,GO:0061013,GO:0065007,GO:0065008,GO:0070013,GO:0070201,GO:0070848,GO:0070884,GO:0070886,GO:0070887,GO:0070935,GO:0071310,GO:0071363,GO:0071495,GO:0071704,GO:0071774,GO:0071840,GO:0072359,GO:0075522,GO:0080090,GO:0090079,GO:0090087,GO:0090276,GO:0090277,GO:0090304,GO:0090305,GO:0097159,GO:0097458,GO:0106056,GO:0106058,GO:0120025,GO:0120035,GO:0120038,GO:0140097,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1902531,GO:1902533,GO:1902680,GO:1903311,GO:1903312,GO:1903506,GO:1903508,GO:1903530,GO:1903532,GO:1904409,GO:1904411,GO:1904951,GO:1990904,GO:2000026,GO:2000112,GO:2000113,GO:2001141	-	ko:K08524,ko:K13218,ko:K14948,ko:K17844	ko03320,ko04151,ko04659,ko04919,ko04920,ko04932,ko04976,ko05160,ko05200,ko05202,ko05216,ko05222,ko05223,ko05226,map03320,map04151,map04659,map04919,map04920,map04932,map04976,map05160,map05200,map05202,map05216,map05222,map05223,map05226	-	-	-	ko00000,ko00001,ko03000,ko03019,ko03041,ko03310	-	-	-	RRM_1,RRM_5
k59_379300_1	1415778.JQMM01000001_gene1077	1.61e-49	165.0	COG1309@1|root,COG1309@2|Bacteria,1RE2I@1224|Proteobacteria,1SH5N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_105747_1	644801.Psest_3427	1.27e-101	310.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,1RQVT@1236|Gammaproteobacteria,1Z1TJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_1123128_1	888056.HMPREF9062_1590	5.38e-11	66.2	COG0476@1|root,COG0476@2|Bacteria,2GJB6@201174|Actinobacteria,4D4JQ@85005|Actinomycetales	201174|Actinobacteria	H	ThiF family	thiF	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
k59_303069_1	2340.JV46_26680	2.75e-139	401.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,1RNTJ@1236|Gammaproteobacteria,1JB7M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_1164453_2	1122951.ATUE01000006_gene1184	4.09e-55	179.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,3NM0V@468|Moraxellaceae	1236|Gammaproteobacteria	P	COG4149 ABC-type molybdate transport system, permease component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
k59_810284_1	240292.Ava_0231	1.96e-30	118.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,DDE_Tnp_ISAZ013,DUF3105,HTH_28,HTH_33
k59_426390_1	177437.HRM2_48110	1.39e-55	188.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,2MISV@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_145029_1	933262.AXAM01000018_gene974	8.75e-87	273.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MJE7@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k59_108881_1	1121405.dsmv_2306	3.49e-126	377.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria,2MN0D@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Peptidase family M41	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_226632_1	269799.Gmet_0033	2.5e-113	350.0	COG2766@1|root,COG2766@2|Bacteria,1NG7R@1224|Proteobacteria,42P8B@68525|delta/epsilon subdivisions,2WJIU@28221|Deltaproteobacteria,43S2Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PrkA serine protein kinase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_PrkA,PrkA
k59_108886_1	519441.Smon_0503	4.72e-28	117.0	COG0322@1|root,COG0322@2|Bacteria,378EP@32066|Fusobacteria	32066|Fusobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
k59_576680_1	768066.HELO_2352	2.22e-38	133.0	COG0685@1|root,COG0685@2|Bacteria,1RHDY@1224|Proteobacteria,1T0DC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
k59_576680_2	768066.HELO_2353	1.35e-42	148.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,1S185@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0685 5,10-methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
k59_1012926_1	686340.Metal_2490	2.77e-40	141.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,1XG9F@135618|Methylococcales	135618|Methylococcales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1012926_2	203122.Sde_0010	7.28e-17	75.5	2AGHX@1|root,316QI@2|Bacteria,1RI7I@1224|Proteobacteria,1S8W9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_303110_1	760568.Desku_1681	1.56e-39	144.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,260XG@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
k59_498518_1	161156.JQKW01000006_gene1069	3.43e-115	341.0	COG0172@1|root,COG0172@2|Bacteria,2GGY4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_145081_1	335543.Sfum_0540	1.13e-42	157.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2MQHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_1048410_1	1137799.GZ78_28985	6.09e-33	119.0	COG5331@1|root,COG5331@2|Bacteria,1N0MD@1224|Proteobacteria,1SF8F@1236|Gammaproteobacteria,1XQHI@135619|Oceanospirillales	135619|Oceanospirillales	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
k59_1048410_2	1283300.ATXB01000001_gene1359	1.11e-40	136.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1XF7U@135618|Methylococcales	135618|Methylococcales	K	Belongs to the P(II) protein family	-	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
k59_890346_1	331869.BAL199_01609	1.35e-35	136.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
k59_654359_1	324925.Ppha_0925	3.45e-72	232.0	COG1236@1|root,COG1236@2|Bacteria,1FER3@1090|Chlorobi	1090|Chlorobi	J	PFAM beta-lactamase domain protein	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
k59_576772_1	349521.HCH_03020	2.34e-46	169.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1XHSN@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_1164559_1	1255043.TVNIR_3082	3.62e-08	52.4	2EPYJ@1|root,33HJ5@2|Bacteria,1NGGR@1224|Proteobacteria,1SI73@1236|Gammaproteobacteria,1X1UP@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1164559_2	1122619.KB892280_gene1584	1.56e-18	85.9	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,3T24Z@506|Alcaligenaceae	28216|Betaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
k59_616722_1	1223542.GM1_066_00020	2.56e-05	50.4	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4GECQ@85026|Gordoniaceae	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
k59_616722_2	575588.ACPN01000077_gene1627	2.7e-07	50.4	COG2963@1|root,COG2963@2|Bacteria,1MZ5C@1224|Proteobacteria,1SZ9Z@1236|Gammaproteobacteria,3NTD2@468|Moraxellaceae	1236|Gammaproteobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_1085327_1	9593.ENSGGOP00000016614	1.98e-109	322.0	2A5I7@1|root,2RY9P@2759|Eukaryota,39WY2@33154|Opisthokonta,3BI5T@33208|Metazoa,3CT28@33213|Bilateria,47Z1D@7711|Chordata,4912K@7742|Vertebrata,3J8DQ@40674|Mammalia,35K50@314146|Euarchontoglires,4M6SH@9443|Primates,4N59Z@9604|Hominidae	33208|Metazoa	C	response to leukemia inhibitory factor	LAPTM5	GO:0000323,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0034097,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071345,GO:0071944,GO:1990823,GO:1990830	-	ko:K12387	ko04142,map04142	-	-	-	ko00000,ko00001	-	-	-	Mtp
k59_694503_1	768066.HELO_3559	9.59e-67	232.0	COG0591@1|root,COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1QTSW@1224|Proteobacteria,1T1G2@1236|Gammaproteobacteria,1XH3H@135619|Oceanospirillales	135619|Oceanospirillales	T	COG0591 Na proline symporter	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,SSF
k59_616730_2	948106.AWZT01000010_gene2268	2.62e-14	73.2	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VRN8@28216|Betaproteobacteria,1K4S6@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_541440_2	864051.BurJ1DRAFT_3699	3.25e-08	57.0	COG0845@1|root,COG0845@2|Bacteria,1RC4B@1224|Proteobacteria,2VSI9@28216|Betaproteobacteria,1KNGQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1164574_1	754477.Q7C_2236	1.51e-78	245.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,1RPR6@1236|Gammaproteobacteria,460A9@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH,TusA
k59_303180_1	670292.JH26_20780	4.63e-92	276.0	COG0778@1|root,COG0778@2|Bacteria,1MY39@1224|Proteobacteria,2TTZC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0778 Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_184291_1	1123253.AUBD01000007_gene703	1.78e-09	57.8	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1X3NP@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_184291_2	553385.JEMF01000062_gene1555	6.26e-102	303.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria,1XIGQ@135619|Oceanospirillales	135619|Oceanospirillales	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_145128_1	335543.Sfum_1328	7.59e-77	241.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria,43A0M@68525|delta/epsilon subdivisions,2X9UN@28221|Deltaproteobacteria,2MS7U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
k59_850923_1	272630.MexAM1_META1p2043	2.56e-111	337.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,2TRJG@28211|Alphaproteobacteria,1JR93@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM SpoVR family protein	MA20_00990	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
k59_810408_1	863365.XHC_1600	5.2e-47	167.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria,1X3WH@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_772637_1	1163407.UU7_00817	2e-80	265.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1X527@135614|Xanthomonadales	135614|Xanthomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_541474_1	6087.XP_002157451.2	1.5e-05	52.4	KOG0547@1|root,KOG0547@2759|Eukaryota,38BB8@33154|Opisthokonta,3BE1Z@33208|Metazoa	33208|Metazoa	U	negative regulation of cell growth involved in cardiac muscle cell development	TOMM70A	GO:0001101,GO:0001558,GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005742,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0010243,GO:0010611,GO:0010614,GO:0010721,GO:0014070,GO:0014741,GO:0014743,GO:0015031,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016202,GO:0019867,GO:0022804,GO:0022857,GO:0022884,GO:0030308,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031306,GO:0031307,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032592,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0040008,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0043200,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043502,GO:0044057,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045184,GO:0045595,GO:0045596,GO:0045843,GO:0045926,GO:0046620,GO:0046621,GO:0046907,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048634,GO:0048635,GO:0048638,GO:0048640,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051093,GO:0051128,GO:0051147,GO:0051148,GO:0051153,GO:0051154,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051241,GO:0051641,GO:0051649,GO:0055021,GO:0055022,GO:0055024,GO:0055026,GO:0055085,GO:0060284,GO:0060420,GO:0061050,GO:0061052,GO:0061117,GO:0065007,GO:0070201,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0090087,GO:0090257,GO:0097066,GO:0097068,GO:0098573,GO:0098588,GO:0098796,GO:0098798,GO:0098799,GO:0098805,GO:1901698,GO:1901700,GO:1901861,GO:1901862,GO:1904386,GO:1904589,GO:1904591,GO:1904680,GO:1904951,GO:1905207,GO:1905208,GO:2000026,GO:2000725,GO:2000726	-	ko:K17768	-	-	-	-	ko00000,ko02000,ko03029	3.A.8.1	-	-	TPR_1,TPR_16,TPR_2,TPR_8
k59_1246828_1	1321786.HMPREF1992_00415	4.99e-10	62.4	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4H4TE@909932|Negativicutes	909932|Negativicutes	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
k59_264144_1	429009.Adeg_1078	6.97e-70	231.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1UT78@1239|Firmicutes,24A6H@186801|Clostridia,42FPJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_9,FlpD,Pyr_redox_2
k59_498685_1	715451.ambt_09115	2.2e-12	68.6	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464X3@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran,DUF805
k59_928366_2	768671.ThimaDRAFT_0841	1.34e-28	117.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1WYW3@135613|Chromatiales	135613|Chromatiales	O	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8,Trans_reg_C
k59_850980_1	290317.Cpha266_0017	4.3e-26	108.0	COG5433@1|root,COG5433@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_1204292_1	880072.Desac_0500	7.22e-78	246.0	COG1804@1|root,COG1804@2|Bacteria,1NWFC@1224|Proteobacteria,4300F@68525|delta/epsilon subdivisions,2X2A6@28221|Deltaproteobacteria,2MRS4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_1013069_1	1162668.LFE_0640	6.46e-11	66.2	COG1624@1|root,COG1624@2|Bacteria,3J0XP@40117|Nitrospirae	40117|Nitrospirae	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
k59_303273_2	1007103.AFHW01000001_gene4982	0.00035	42.4	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,26RHB@186822|Paenibacillaceae	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_810477_1	156889.Mmc1_2685	9.59e-43	159.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
k59_303279_1	1385517.N800_07165	3.55e-34	134.0	COG1461@1|root,COG1461@2|Bacteria,1NKAM@1224|Proteobacteria,1SHAC@1236|Gammaproteobacteria,1X3IB@135614|Xanthomonadales	135614|Xanthomonadales	S	Dak2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
k59_694628_1	1117319.PSPO_11296	2.28e-51	182.0	COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria,2Q0ZC@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,ShlB
k59_498778_1	756272.Plabr_3831	3.26e-19	91.7	COG2208@1|root,COG2208@2|Bacteria,2J02Z@203682|Planctomycetes	203682|Planctomycetes	T	COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
k59_459308_1	189753.AXAS01000058_gene148	4.41e-106	323.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSTW@28211|Alphaproteobacteria,3JW5G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_541556_1	1047013.AQSP01000139_gene2342	6.02e-87	276.0	COG1529@1|root,COG1529@2|Bacteria,2NPHP@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_928426_1	485915.Dret_0234	0.000168	44.3	2CDHP@1|root,32RXU@2|Bacteria,1N1BP@1224|Proteobacteria,42TPT@68525|delta/epsilon subdivisions,2WQE6@28221|Deltaproteobacteria,2MB0T@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	RsbT co-antagonist protein rsbRD N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
k59_928426_2	1121405.dsmv_2242	2.76e-56	186.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,42MZU@68525|delta/epsilon subdivisions,2WKKU@28221|Deltaproteobacteria,2MI6J@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
k59_426702_1	883.DvMF_0050	1.47e-22	88.6	COG0724@1|root,COG0724@2|Bacteria,1N0P8@1224|Proteobacteria,43B6G@68525|delta/epsilon subdivisions,2WQ1E@28221|Deltaproteobacteria,2MH3Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_654511_1	221288.JH992901_gene1783	6.99e-07	51.6	2AFHA@1|root,315HT@2|Bacteria,1G5WD@1117|Cyanobacteria,1JMA6@1189|Stigonemataceae	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
k59_1085473_1	1121035.AUCH01000003_gene1255	2.06e-39	144.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria,2KV5T@206389|Rhodocyclales	206389|Rhodocyclales	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_1085473_2	983917.RGE_35750	2.58e-49	169.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,2VK03@28216|Betaproteobacteria,1KJYT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	hoxK	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_1125707_1	292459.STH3262	1.45e-13	76.3	COG0674@1|root,COG1013@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169,ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N,TPP_enzyme_C
k59_928440_1	335543.Sfum_3013	1.16e-69	236.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
k59_810516_1	1232410.KI421419_gene2478	3.42e-98	303.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2WIIV@28221|Deltaproteobacteria,43RYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
k59_303325_1	9606.ENSP00000262947	7.24e-122	347.0	2AR16@1|root,2RZK9@2759|Eukaryota,3A044@33154|Opisthokonta,3BPIN@33208|Metazoa,3D717@33213|Bilateria,48AHR@7711|Chordata,490WN@7742|Vertebrata,3J3Y2@40674|Mammalia,35GIU@314146|Euarchontoglires,4MJGY@9443|Primates,4N6AV@9604|Hominidae	33208|Metazoa	T	Uncharacterised protein family UPF0556	C19orf10	GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006355,GO:0006357,GO:0006950,GO:0006986,GO:0007154,GO:0007165,GO:0008150,GO:0008284,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010941,GO:0012505,GO:0014066,GO:0014068,GO:0019219,GO:0019220,GO:0019222,GO:0022603,GO:0023051,GO:0023052,GO:0023056,GO:0030968,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031401,GO:0031974,GO:0032268,GO:0032270,GO:0033554,GO:0034620,GO:0034976,GO:0035966,GO:0035967,GO:0036498,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043408,GO:0043410,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045765,GO:0045766,GO:0045893,GO:0045935,GO:0045937,GO:0045944,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050678,GO:0050679,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051171,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051716,GO:0051896,GO:0051897,GO:0060255,GO:0060548,GO:0065007,GO:0070013,GO:0070887,GO:0071310,GO:0080090,GO:1901342,GO:1902531,GO:1902533,GO:1902680,GO:1903506,GO:1903508,GO:1904018,GO:2000026,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	UPF0556
k59_969643_1	882.DVU_0285	4.51e-42	145.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2WNKF@28221|Deltaproteobacteria,2MG1V@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
k59_516650_1	1232437.KL662006_gene4387	1.26e-38	131.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	pkn5	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	AAA_16,GAF,HAMP,Pkinase,Response_reg,SpoIIE,dCache_1
k59_9964_1	717785.HYPMC_1121	2.68e-91	281.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,3N676@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	T	response regulator	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
k59_166694_1	566466.NOR53_2419	1.87e-61	206.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,1J8KD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_480135_1	177437.HRM2_22350	1.08e-77	241.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria,2MJ8Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Hydrogenase (NiFe) small subunit HydA	hydA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.12.2.1,1.12.5.1,1.12.7.2,1.12.99.6	ko:K00534,ko:K05927,ko:K06282,ko:K18008	ko00633,ko01120,map00633,map01120	-	R00019,R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
k59_441001_1	335543.Sfum_1666	1.04e-30	117.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2MQGR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
k59_1067701_1	1123276.KB893246_gene854	1.13e-63	211.0	COG3385@1|root,COG3385@2|Bacteria,4P02Y@976|Bacteroidetes,47TUA@768503|Cytophagia	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_1185660_1	1265505.ATUG01000001_gene3177	6.45e-67	218.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,42QTW@68525|delta/epsilon subdivisions,2WMNU@28221|Deltaproteobacteria,2MJYF@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
k59_363059_1	644282.Deba_0404	1.27e-42	147.0	COG2128@1|root,COG2128@2|Bacteria,1RHU7@1224|Proteobacteria,42USP@68525|delta/epsilon subdivisions,2WR2Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1225392_1	862751.SACTE_5357	5.17e-31	119.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_89135_1	1122194.AUHU01000002_gene2491	2.92e-07	51.2	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,467ZU@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_89135_2	1239962.C943_02735	1.72e-09	59.3	2E30A@1|root,32Y0V@2|Bacteria,4NPVG@976|Bacteroidetes,47RZP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_676075_2	1415780.JPOG01000001_gene2845	9.18e-28	108.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1X737@135614|Xanthomonadales	135614|Xanthomonadales	P	Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_676075_3	1123020.AUIE01000001_gene2133	6.89e-27	101.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,1YJY7@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
k59_127646_1	1499967.BAYZ01000073_gene1999	6.72e-40	144.0	COG0624@1|root,COG0624@2|Bacteria,2NPIK@2323|unclassified Bacteria	2|Bacteria	E	Peptidase dimerisation domain	cpg2	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_127646_2	1379698.RBG1_1C00001G0054	3.06e-87	268.0	COG2502@1|root,COG2502@2|Bacteria,2NNKP@2323|unclassified Bacteria	2|Bacteria	E	Aspartate-ammonia ligase	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	AsnA
k59_950355_1	1266925.JHVX01000003_gene596	3.76e-44	164.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,371ZN@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
k59_871800_1	861299.J421_4478	2.74e-77	247.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_363086_2	329726.AM1_6133	4.66e-17	81.6	COG0534@1|root,COG0534@2|Bacteria,1G2M4@1117|Cyanobacteria	1117|Cyanobacteria	V	efflux protein, MATE family	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_1225438_1	592015.HMPREF1705_01721	1e-23	92.4	28XQZ@1|root,2ZJMK@2|Bacteria,3TCGY@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1225438_2	36809.MAB_1165	1.05e-34	131.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,233AZ@1762|Mycobacteriaceae	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_166785_1	335543.Sfum_0020	2.54e-102	321.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2MQ92@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_205818_2	335543.Sfum_3245	5.25e-10	59.3	COG0589@1|root,COG0589@2|Bacteria,1REA3@1224|Proteobacteria,42RXY@68525|delta/epsilon subdivisions,2WNM6@28221|Deltaproteobacteria,2MSDJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_990566_1	401526.TcarDRAFT_1856	2.33e-20	95.1	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4H77H@909932|Negativicutes	909932|Negativicutes	C	L-lactate permease	-	-	-	-	-	-	-	-	-	-	-	-	Lactate_perm
k59_558525_1	1167006.UWK_01328	2.13e-73	231.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42VXX@68525|delta/epsilon subdivisions,2X6CT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_284272_1	269799.Gmet_0413	3.16e-12	67.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,43U76@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_284272_2	536233.CLO_0185	1.74e-09	60.1	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,36DWB@31979|Clostridiaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k59_910845_1	999550.KI421507_gene1978	2.26e-192	541.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2TTH8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32
k59_950392_1	96561.Dole_2741	7.26e-79	238.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2MJTB@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
k59_245333_1	745014.OMB55_00014300	5.94e-32	117.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria,1J698@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
k59_89200_1	228410.NE0866	1.48e-05	46.6	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,3720S@32003|Nitrosomonadales	28216|Betaproteobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_89200_2	1121937.AUHJ01000008_gene2056	5.99e-10	62.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,4673B@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host	djlA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0051087,GO:0071944	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
k59_1067807_1	391615.ABSJ01000039_gene1920	6.18e-74	233.0	COG0803@1|root,COG0803@2|Bacteria,1PQEX@1224|Proteobacteria,1RYA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	periplasmic solute binding protein	znuA	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
k59_10095_2	1123228.AUIH01000001_gene1413	1.4e-30	115.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,1XK5F@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_754428_2	1232410.KI421425_gene1553	1.66e-48	174.0	COG4932@1|root,COG4932@2|Bacteria,1QZFW@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_950413_1	648885.KB316282_gene671	6.53e-64	220.0	COG1429@1|root,COG1429@2|Bacteria,1MU5W@1224|Proteobacteria,2TQVD@28211|Alphaproteobacteria,1JTJ9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	TIGRFAM magnesium chelatase, H subunit	bchH	-	6.6.1.1	ko:K03403	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel,DUF3479
k59_519761_2	1429046.RR21198_4520	8.46e-05	46.2	COG1656@1|root,COG1656@2|Bacteria,2GMQR@201174|Actinobacteria,4FZ3N@85025|Nocardiaceae	201174|Actinobacteria	T	Mut7-C ubiquitin	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
k59_832792_1	930169.B5T_03965	3.8e-106	321.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XIGF@135619|Oceanospirillales	135619|Oceanospirillales	E	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_950418_1	1121456.ATVA01000013_gene1161	7.93e-20	87.4	COG4659@1|root,COG4659@2|Bacteria,1PPK1@1224|Proteobacteria,42TAI@68525|delta/epsilon subdivisions,2WNZU@28221|Deltaproteobacteria,2M9S6@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k59_950418_2	1121918.ARWE01000001_gene21	8.53e-43	150.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,42QE5@68525|delta/epsilon subdivisions,2WM8R@28221|Deltaproteobacteria,43S58@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NQR2, RnfD, RnfE family	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_323457_1	243233.MCA0390	1.5e-104	313.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1XEFA@135618|Methylococcales	135618|Methylococcales	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
k59_715956_1	234831.PSM_A2331	3.22e-23	103.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2PZGG@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	barA	GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg
k59_441151_1	1121440.AUMA01000009_gene695	1.14e-55	185.0	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,42QQ7@68525|delta/epsilon subdivisions,2WN8Z@28221|Deltaproteobacteria,2M8UD@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
k59_1067863_1	1121456.ATVA01000011_gene1345	3.67e-85	273.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1QZPK@1224|Proteobacteria,42NQE@68525|delta/epsilon subdivisions,2WJPH@28221|Deltaproteobacteria,2M8MZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9,Response_reg
k59_49448_1	1089552.KI911559_gene2470	1.67e-38	146.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,2JQBT@204441|Rhodospirillales	204441|Rhodospirillales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_402418_1	56780.SYN_02149	3.85e-66	216.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria,2MQ4C@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_441187_1	485915.Dret_1795	2.9e-70	225.0	COG0475@1|root,COG0475@2|Bacteria,1RFKE@1224|Proteobacteria,43B2P@68525|delta/epsilon subdivisions,2X6GM@28221|Deltaproteobacteria,2M9P0@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_127773_1	360910.BAV0180	7.31e-85	262.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2VJYK@28216|Betaproteobacteria,3T1UZ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	baeB	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_990695_1	472759.Nhal_0103	8.72e-53	181.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1WX09@135613|Chromatiales	135613|Chromatiales	P	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
k59_716024_1	1123261.AXDW01000001_gene1072	1.04e-86	280.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1X31R@135614|Xanthomonadales	135614|Xanthomonadales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_832858_1	67356.KL575585_gene8134	3.33e-69	224.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
k59_284386_1	686340.Metal_2096	5.38e-96	295.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,1XEM6@135618|Methylococcales	135618|Methylococcales	F	Thymidine phosphorylase	-	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
k59_793558_1	1417296.U879_08050	1.09e-101	304.0	COG1856@1|root,COG1856@2|Bacteria,1R6PW@1224|Proteobacteria,2U1YU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Radical SAM	-	-	-	ko:K09711	-	-	-	-	ko00000	-	-	-	Radical_SAM
k59_205933_1	666685.R2APBS1_3947	3.95e-58	202.0	COG1257@1|root,COG1577@1|root,COG1257@2|Bacteria,COG1577@2|Bacteria,1MXVE@1224|Proteobacteria,1RS9R@1236|Gammaproteobacteria,1X8RF@135614|Xanthomonadales	135614|Xanthomonadales	I	Hydroxymethylglutaryl-coenzyme A reductase	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N,HMG-CoA_red
k59_754518_1	77586.LPERR02G28540.1	9.37e-31	128.0	COG1404@1|root,2QZDA@2759|Eukaryota,37QS2@33090|Viridiplantae,3GD1X@35493|Streptophyta,3KNAP@4447|Liliopsida,3IFQJ@38820|Poales	35493|Streptophyta	G	Subtilase family	-	GO:0001763,GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0006508,GO:0006807,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009505,GO:0009653,GO:0010016,GO:0010150,GO:0010223,GO:0010346,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0031090,GO:0032501,GO:0032502,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0048046,GO:0048366,GO:0048367,GO:0048646,GO:0048731,GO:0048827,GO:0048856,GO:0070011,GO:0071704,GO:0071944,GO:0090693,GO:0098588,GO:0098805,GO:0099402,GO:0140096,GO:1901564,GO:1905393	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8
k59_754523_1	234267.Acid_5892	4.33e-66	218.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
k59_754526_1	1123023.JIAI01000004_gene8131	5.57e-56	183.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DZ0W@85010|Pseudonocardiales	201174|Actinobacteria	E	Branched-chain amino acid transport	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_284414_1	3659.XP_004169763.1	2.11e-19	92.0	COG1233@1|root,KOG4254@2759|Eukaryota,37K3E@33090|Viridiplantae,3G9QZ@35493|Streptophyta,4JHCZ@91835|fabids	35493|Streptophyta	H	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,DAO,NAD_binding_8
k59_910963_1	59374.Fisuc_0103	1.3e-05	49.7	COG0265@1|root,COG0526@1|root,COG0265@2|Bacteria,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,PDZ_2,Redoxin,Trypsin_2
k59_1225666_1	56780.SYN_02213	1.27e-86	277.0	COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1R891@1224|Proteobacteria,42P2C@68525|delta/epsilon subdivisions,2WJZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
k59_402470_1	991905.SL003B_1434	3.95e-50	171.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2TQQC@28211|Alphaproteobacteria,4BPRI@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_10213_1	1116472.MGMO_17c00180	2.35e-112	350.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1XDY0@135618|Methylococcales	135618|Methylococcales	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_950526_1	1121405.dsmv_0673	4.44e-45	154.0	COG0619@1|root,COG0619@2|Bacteria,1Q039@1224|Proteobacteria,42RI8@68525|delta/epsilon subdivisions,2WNSV@28221|Deltaproteobacteria,2MK1S@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Cobalt transport protein	-	-	-	ko:K16783,ko:K16785	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
k59_871994_1	391625.PPSIR1_17740	2.88e-68	225.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria,2YU85@29|Myxococcales	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
k59_1185890_1	404589.Anae109_2223	3.01e-20	88.6	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,42R1J@68525|delta/epsilon subdivisions,2WQE8@28221|Deltaproteobacteria,2YVQE@29|Myxococcales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_1185890_2	589865.DaAHT2_1460	0.000121	42.4	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,42SHZ@68525|delta/epsilon subdivisions,2WPFZ@28221|Deltaproteobacteria,2MK53@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_127832_1	880072.Desac_0487	8.66e-41	138.0	2DWSR@1|root,341Q6@2|Bacteria,1Q538@1224|Proteobacteria,430G3@68525|delta/epsilon subdivisions,2WVK2@28221|Deltaproteobacteria,2MRYW@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_89353_1	479434.Sthe_0514	1.09e-72	241.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,27XY6@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_130270_2	1122603.ATVI01000005_gene3112	8.44e-43	150.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1X4AH@135614|Xanthomonadales	135614|Xanthomonadales	E	cystathionine	-	-	4.4.1.1	ko:K01758	ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230	M00338	R00782,R01001,R02408,R04770,R04930,R09366	RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
k59_579732_1	589873.EP13_06315	3.53e-36	136.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,464JB@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_1249282_1	1304885.AUEY01000015_gene2996	1.46e-50	179.0	COG1219@1|root,COG1219@2|Bacteria,1MWIZ@1224|Proteobacteria,42N1Z@68525|delta/epsilon subdivisions,2WJUS@28221|Deltaproteobacteria,2MHMD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the ClpX chaperone family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
k59_1128193_1	1379270.AUXF01000001_gene2163	1.31e-74	238.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,PHP
k59_186840_1	1120970.AUBZ01000007_gene2982	1.12e-81	253.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,465K2@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k59_853422_1	335543.Sfum_2891	2.6e-91	288.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,2MQCA@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like
k59_30631_1	706587.Desti_4373	1.08e-100	310.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2MQRK@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
k59_657019_1	2340.JV46_26900	4.11e-42	158.0	COG0834@1|root,COG0834@2|Bacteria,1N315@1224|Proteobacteria,1T21D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
k59_30666_1	1287276.X752_15825	1.5e-10	57.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,2U95S@28211|Alphaproteobacteria,43KG4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
k59_30666_2	861208.AGROH133_07152	4.75e-83	253.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2TTKD@28211|Alphaproteobacteria,4B9GD@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_657034_1	9601.ENSPPYP00000019467	3.85e-122	358.0	KOG1523@1|root,KOG1523@2759|Eukaryota,38FWT@33154|Opisthokonta,3BD4C@33208|Metazoa,3CSS9@33213|Bilateria,4874V@7711|Chordata,48Y4I@7742|Vertebrata,3JAYS@40674|Mammalia,35NJE@314146|Euarchontoglires,4MD8D@9443|Primates,4MU22@9604|Hominidae	33208|Metazoa	Z	WD domain, G-beta repeat	ARPC1B	GO:0000902,GO:0000904,GO:0001654,GO:0001700,GO:0001745,GO:0002252,GO:0002253,GO:0002376,GO:0002429,GO:0002431,GO:0002433,GO:0002682,GO:0002684,GO:0002757,GO:0002764,GO:0002768,GO:0003674,GO:0003779,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005885,GO:0006810,GO:0006886,GO:0006897,GO:0006909,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007154,GO:0007155,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007399,GO:0007409,GO:0007413,GO:0007423,GO:0008037,GO:0008038,GO:0008064,GO:0008092,GO:0008104,GO:0008150,GO:0008407,GO:0008593,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010638,GO:0010646,GO:0010647,GO:0014070,GO:0015031,GO:0015629,GO:0015833,GO:0016043,GO:0016192,GO:0022008,GO:0022402,GO:0022416,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0030029,GO:0030030,GO:0030036,GO:0030037,GO:0030154,GO:0030182,GO:0030588,GO:0030589,GO:0030832,GO:0030833,GO:0030838,GO:0031175,GO:0031334,GO:0031344,GO:0031346,GO:0031532,GO:0032271,GO:0032273,GO:0032355,GO:0032501,GO:0032502,GO:0032535,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033627,GO:0033993,GO:0034314,GO:0034613,GO:0036284,GO:0038093,GO:0038094,GO:0038096,GO:0042221,GO:0042886,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043627,GO:0044087,GO:0044089,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045010,GO:0045184,GO:0045747,GO:0046907,GO:0048013,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048592,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048749,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051015,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051489,GO:0051491,GO:0051493,GO:0051495,GO:0051641,GO:0051649,GO:0051716,GO:0060491,GO:0061564,GO:0065007,GO:0065008,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0090066,GO:0090527,GO:0090596,GO:0097435,GO:0098657,GO:0106030,GO:0110053,GO:0120032,GO:0120034,GO:0120035,GO:0120036,GO:0120039,GO:1901700,GO:1902903,GO:1902905	-	ko:K05757	ko04144,ko04666,ko04810,ko05100,ko05130,ko05131,ko05132,map04144,map04666,map04810,map05100,map05130,map05131,map05132	-	-	-	ko00000,ko00001,ko04131,ko04812	-	-	-	WD40
k59_579787_1	1027273.GZ77_07045	2.32e-70	229.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,1RNY5@1236|Gammaproteobacteria,1XHVH@135619|Oceanospirillales	135619|Oceanospirillales	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	etf	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8
k59_775433_1	247634.GPB2148_2605	8.69e-65	206.0	COG2273@1|root,COG2273@2|Bacteria,1NSB1@1224|Proteobacteria,1SM0Y@1236|Gammaproteobacteria,1J7UI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_429686_1	1144275.COCOR_00403	2.79e-58	206.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria,2Z33Y@29|Myxococcales	28221|Deltaproteobacteria	M	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
k59_186881_1	1121405.dsmv_0234	4.97e-81	258.0	COG1055@1|root,COG1055@2|Bacteria,1N68M@1224|Proteobacteria,42PD9@68525|delta/epsilon subdivisions,2WKRV@28221|Deltaproteobacteria,2MMQP@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
k59_972420_1	1123261.AXDW01000001_gene1319	2.23e-12	65.9	COG2404@1|root,COG2404@2|Bacteria,1QWB5@1224|Proteobacteria,1T3KS@1236|Gammaproteobacteria,1X9QI@135614|Xanthomonadales	135614|Xanthomonadales	S	COG0608 Single-stranded DNA-specific exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_69487_1	335543.Sfum_3923	1.99e-66	220.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MRU@68525|delta/epsilon subdivisions,2WIQX@28221|Deltaproteobacteria,2MRI6@213462|Syntrophobacterales	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_461933_1	864051.BurJ1DRAFT_4160	3.33e-13	73.2	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2WF5Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1249373_1	1121939.L861_01755	9.31e-56	196.0	COG3629@1|root,COG3629@2|Bacteria,1QU9N@1224|Proteobacteria	1224|Proteobacteria	K	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD
k59_345067_2	390989.JOEG01000002_gene4365	3.44e-18	86.7	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4D92R@85008|Micromonosporales	201174|Actinobacteria	BQ	histone deacetylase	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
k59_305835_1	614083.AWQR01000029_gene2067	3.64e-13	72.4	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria,4AA3N@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	cyc	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_1088208_1	203122.Sde_0855	1.82e-46	162.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,465Y3@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_544145_1	95619.PM1_0200635	1.41e-27	105.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
k59_697264_1	1123373.ATXI01000003_gene1284	3.8e-84	265.0	COG0318@1|root,COG0318@2|Bacteria,2GH7C@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
k59_429816_1	28229.ND2E_0546	2.61e-19	88.2	COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,2Q610@267889|Colwelliaceae	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
k59_1128351_2	396588.Tgr7_1006	6.1e-38	129.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,1S8U6@1236|Gammaproteobacteria,1WYZR@135613|Chromatiales	135613|Chromatiales	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_345138_1	261292.Nit79A3_1992	5.09e-13	68.2	28PU4@1|root,2ZCF6@2|Bacteria,1N6FV@1224|Proteobacteria,2WFI6@28216|Betaproteobacteria,373J1@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_579892_1	314254.OA2633_03741	7.54e-08	53.1	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1QU0Y@1224|Proteobacteria,2TWDU@28211|Alphaproteobacteria,440TK@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_579892_2	1122137.AQXF01000003_gene1871	5.62e-14	73.6	COG0845@1|root,COG0845@2|Bacteria,1MV1T@1224|Proteobacteria,2VFH0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_813219_1	1265505.ATUG01000002_gene1896	2.9e-61	205.0	COG2308@1|root,COG2308@2|Bacteria,1NG4H@1224|Proteobacteria,42WK0@68525|delta/epsilon subdivisions,2WS0X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_345188_2	526222.Desal_0346	2.17e-14	73.2	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1QZPK@1224|Proteobacteria,42NQE@68525|delta/epsilon subdivisions,2WJPH@28221|Deltaproteobacteria,2M8MZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9,Response_reg
k59_931392_1	398767.Glov_0917	3.18e-85	268.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
k59_429861_1	1121374.KB891586_gene2672	5.21e-68	224.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
k59_736308_1	1123360.thalar_00024	8.41e-35	132.0	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2TR3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
k59_736308_2	381666.H16_A1016	4.69e-18	84.7	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,1K0FS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	xdhB	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_69609_1	572477.Alvin_0308	1.07e-22	101.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1PGAZ@1224|Proteobacteria,1RWZ6@1236|Gammaproteobacteria,1X0SN@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
k59_112019_1	335543.Sfum_0458	7.82e-93	287.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2MR53@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_69611_1	1122194.AUHU01000001_gene52	1.05e-17	84.3	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,4640D@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345	SBP_bac_3,SLT
k59_775617_1	335543.Sfum_0185	5.06e-61	199.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2MRVG@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_112043_1	266748.HY04_12635	1.45e-41	143.0	COG1272@1|root,COG1272@2|Bacteria,4NM95@976|Bacteroidetes,1HYZQ@117743|Flavobacteriia,3ZTX6@59732|Chryseobacterium	976|Bacteroidetes	S	Haemolysin-III related	hly-III	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
k59_579976_1	670307.HYPDE_34573	2.67e-110	328.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2TSHK@28211|Alphaproteobacteria,3N61T@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_775634_1	1283300.ATXB01000002_gene3058	1.15e-19	82.8	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
k59_893373_1	909663.KI867150_gene433	7.21e-112	340.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQB7@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
k59_1088381_1	1121875.KB907546_gene2199	2.43e-73	237.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1I2RR@117743|Flavobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_1051184_1	371042.NG99_00715	1.65e-62	214.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,3X65U@551|Erwinia	1236|Gammaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	GO:0000287,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008312,GO:0008995,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0017151,GO:0019222,GO:0019439,GO:0019899,GO:0022607,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043462,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048519,GO:0050789,GO:0050790,GO:0051095,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902280	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	PNPase_C,RNase_E_G,S1
k59_853671_1	1437882.AZRU01000106_gene6585	4.04e-12	63.2	COG1522@1|root,COG1522@2|Bacteria,1RFT6@1224|Proteobacteria,1S6RJ@1236|Gammaproteobacteria,1YDD9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	helix_turn_helix ASNC type	ybaO	-	-	ko:K05800	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
k59_853671_2	488538.SAR116_0663	1.15e-36	135.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,4BQAI@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_544331_2	469378.Ccur_06230	0.00089	42.4	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CV2Q@84998|Coriobacteriia	84998|Coriobacteriia	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k59_775681_2	314285.KT71_08289	1.15e-65	203.0	COG3791@1|root,COG3791@2|Bacteria,1PSHH@1224|Proteobacteria,1SB5F@1236|Gammaproteobacteria,1J9V7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_736398_1	335543.Sfum_1219	7.98e-104	310.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WJ4D@28221|Deltaproteobacteria,2MQW6@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	yfdZ	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_385669_1	940282.CADQ01000005_gene352	6.52e-34	134.0	COG1231@1|root,COG1231@2|Bacteria,1MWPH@1224|Proteobacteria,2U05G@28211|Alphaproteobacteria,2JVI5@204441|Rhodospirillales	204441|Rhodospirillales	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
k59_1251934_1	1121451.DESAM_21269	2.71e-47	169.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2M91R@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
k59_700009_1	335543.Sfum_3207	5.78e-67	214.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42PRS@68525|delta/epsilon subdivisions,2WK0H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	PFAM aminotransferase, class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
k59_659874_1	1453501.JELR01000002_gene166	8.99e-71	229.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,464NX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
k59_1170708_1	1336245.JAGO01000003_gene588	3.36e-88	286.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1XHKH@135619|Oceanospirillales	135619|Oceanospirillales	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_778354_1	1379281.AVAG01000031_gene106	2.07e-131	402.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2WJPV@28221|Deltaproteobacteria,2M8WP@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	iAF987.Gmet_3512	Aldedh,Pro_dh
k59_1018412_1	1045855.DSC_14995	6.71e-42	157.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1X341@135614|Xanthomonadales	135614|Xanthomonadales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k59_114745_1	266264.Rmet_4347	8.57e-22	91.3	COG0599@1|root,COG0599@2|Bacteria,1QW4R@1224|Proteobacteria,2WHAR@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_150806_1	550540.Fbal_1886	1.02e-78	249.0	COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,1RP9M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_464729_1	1235800.C819_02054	5.98e-06	53.9	COG1344@1|root,COG1344@2|Bacteria,1UZ0D@1239|Firmicutes,25DJG@186801|Clostridia,27U9X@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Bacterial flagellin N-terminal helical region	-	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
k59_1018420_1	933262.AXAM01000013_gene1313	1.68e-62	204.0	COG2768@1|root,COG2768@2|Bacteria,1MXMK@1224|Proteobacteria,42M2Z@68525|delta/epsilon subdivisions,2WIN6@28221|Deltaproteobacteria,2MI71@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF362)	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_4,Fer4_6,Fer4_7
k59_114777_1	247639.MGP2080_12048	6.37e-18	88.6	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,1RP6I@1236|Gammaproteobacteria,1J88H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1757 Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
k59_1090999_1	1242864.D187_001096	2.18e-31	123.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,2YVMB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_934123_1	118797.XP_007471489.1	4.39e-137	415.0	KOG0401@1|root,KOG0401@2759|Eukaryota,38C69@33154|Opisthokonta,3BD2F@33208|Metazoa,3CUP3@33213|Bilateria,47Z5N@7711|Chordata,4907H@7742|Vertebrata,3J24Z@40674|Mammalia,4J9X9@91561|Cetartiodactyla	33208|Metazoa	J	Eukaryotic translation initiation factor 4 gamma 2	EIF4G2	GO:0001558,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0007049,GO:0007050,GO:0007275,GO:0007399,GO:0007423,GO:0008135,GO:0008150,GO:0008152,GO:0008219,GO:0008361,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010467,GO:0010468,GO:0010506,GO:0010507,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0016043,GO:0016281,GO:0019222,GO:0019538,GO:0022008,GO:0022402,GO:0022416,GO:0022603,GO:0022604,GO:0030154,GO:0030307,GO:0030424,GO:0030516,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031344,GO:0031346,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032535,GO:0032991,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0040008,GO:0042995,GO:0043005,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045727,GO:0045773,GO:0045786,GO:0045927,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048638,GO:0048639,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050770,GO:0050772,GO:0050773,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051726,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0060998,GO:0060999,GO:0061387,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0080090,GO:0090066,GO:0097159,GO:0097458,GO:0120025,GO:0120035,GO:1900006,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000026,GO:2000112	-	ko:K03260,ko:K17682	ko03013,ko05416,map03013,map05416	M00428	-	-	ko00000,ko00001,ko00002,ko03012,ko03019,ko03029	-	-	-	MA3,MIF4G,W2
k59_347957_1	1293054.HSACCH_01221	1.43e-49	172.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WAIA@53433|Halanaerobiales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_622289_1	9606.ENSP00000307940	0.0	1714.0	COG0480@1|root,KOG0469@2759|Eukaryota,38CUM@33154|Opisthokonta,3BAEX@33208|Metazoa,3CUB5@33213|Bilateria,48038@7711|Chordata,48ZMF@7742|Vertebrata,3JCFE@40674|Mammalia,35NK4@314146|Euarchontoglires,4M987@9443|Primates,4N4CM@9604|Hominidae	33208|Metazoa	J	translation elongation factor activity	EEF2	GO:0000302,GO:0001101,GO:0001775,GO:0002039,GO:0002244,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002520,GO:0002931,GO:0003008,GO:0003009,GO:0003012,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003779,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006412,GO:0006414,GO:0006417,GO:0006518,GO:0006807,GO:0006810,GO:0006887,GO:0006936,GO:0006941,GO:0006950,GO:0006952,GO:0006955,GO:0006979,GO:0007275,GO:0007399,GO:0007517,GO:0007519,GO:0007568,GO:0007584,GO:0008092,GO:0008097,GO:0008135,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009059,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0012505,GO:0014009,GO:0014070,GO:0014706,GO:0016020,GO:0016192,GO:0016234,GO:0016235,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019222,GO:0019538,GO:0019843,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0030097,GO:0030141,GO:0030154,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031410,GO:0031667,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032270,GO:0032355,GO:0032501,GO:0032502,GO:0032940,GO:0032991,GO:0033273,GO:0033554,GO:0033993,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034774,GO:0034976,GO:0035914,GO:0036230,GO:0042063,GO:0042119,GO:0042221,GO:0042493,GO:0042542,GO:0042742,GO:0042788,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045055,GO:0045121,GO:0045321,GO:0045471,GO:0045727,GO:0046677,GO:0046903,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048534,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050829,GO:0050879,GO:0050881,GO:0050896,GO:0051015,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051593,GO:0051704,GO:0051707,GO:0051716,GO:0060205,GO:0060255,GO:0060537,GO:0060538,GO:0061061,GO:0065007,GO:0070013,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:0097305,GO:0097708,GO:0098542,GO:0098589,GO:0098805,GO:0098857,GO:0099503,GO:0101002,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901698,GO:1901700,GO:1904813,GO:1990089,GO:1990090,GO:1990416,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K03234	ko04152,ko04921,map04152,map04921	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_622306_1	648757.Rvan_1735	8.23e-43	158.0	COG1519@1|root,COG2121@1|root,COG1519@2|Bacteria,COG2121@2|Bacteria,1MU9F@1224|Proteobacteria,2TS37@28211|Alphaproteobacteria,3N83H@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	Domain of unknown function (DUF374)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
k59_33618_1	941449.dsx2_1001	3.94e-81	269.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1RCHY@1224|Proteobacteria,42R1G@68525|delta/epsilon subdivisions,2WMR7@28221|Deltaproteobacteria,2M83U@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
k59_504337_1	1121374.KB891586_gene2791	8.43e-17	83.6	COG3182@1|root,COG3182@2|Bacteria,1QVX4@1224|Proteobacteria,1T2MJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
k59_46866_1	1117647.M5M_18065	2.2e-31	122.0	COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,1RPHS@1236|Gammaproteobacteria,1J54J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Fatty acid desaturase	alkB1	GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase
k59_321255_1	1265503.KB905160_gene2871	8.99e-79	262.0	28HKI@1|root,2Z7VC@2|Bacteria,1MW0I@1224|Proteobacteria,1RQ5H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_712913_1	83219.PM02_08380	2.65e-60	200.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria,3ZUV2@60136|Sulfitobacter	28211|Alphaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k59_752270_1	1121396.KB892913_gene116	1.03e-105	319.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42WI2@68525|delta/epsilon subdivisions,2WRPD@28221|Deltaproteobacteria,2MQ18@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_438955_1	1120956.JHZK01000004_gene1349	9.05e-78	255.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2TTAB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Xanthine dehydrogenase	xdhB	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_86997_1	533240.CRC_03464	1.44e-40	139.0	COG2452@1|root,COG2452@2|Bacteria,1G1RP@1117|Cyanobacteria,1HNK4@1161|Nostocales	1117|Cyanobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1,Resolvase
k59_86997_2	402777.KB235904_gene3895	7.65e-74	237.0	COG0675@1|root,COG0675@2|Bacteria,1G4YA@1117|Cyanobacteria,1HAAZ@1150|Oscillatoriales	1117|Cyanobacteria	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_712938_2	85643.Tmz1t_1336	6.3e-19	86.3	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,2VJN1@28216|Betaproteobacteria,2KUIT@206389|Rhodocyclales	206389|Rhodocyclales	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_908915_1	1163617.SCD_n02617	4.35e-72	226.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
k59_556509_1	1265505.ATUG01000002_gene1831	5.28e-200	567.0	COG4799@1|root,COG4799@2|Bacteria,1Q9BU@1224|Proteobacteria,42P34@68525|delta/epsilon subdivisions,2WK9S@28221|Deltaproteobacteria,2MI0B@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	gcdA	-	4.1.1.70	ko:K01615	ko00362,ko00650,ko01120,map00362,map00650,map01120	-	R03028	RC00832	ko00000,ko00001,ko01000,ko02000	3.B.1.1.3	-	-	Carboxyl_trans
k59_282078_1	1089552.KI911559_gene2853	2.53e-81	270.0	COG1429@1|root,COG1429@2|Bacteria,1MU5W@1224|Proteobacteria,2TQVD@28211|Alphaproteobacteria,2JQYC@204441|Rhodospirillales	204441|Rhodospirillales	H	Domain of unknown function (DUF3479)	bchH	-	6.6.1.1	ko:K03403	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel,DUF3479
k59_87007_1	864051.BurJ1DRAFT_4168	8.02e-68	214.0	COG3245@1|root,COG3245@2|Bacteria,1RCEB@1224|Proteobacteria,2VQIB@28216|Betaproteobacteria,1KNAQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_CBB3
k59_752301_1	794846.AJQU01000086_gene4292	5.34e-32	128.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4BAVP@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16
k59_87023_1	880072.Desac_0968	1.01e-50	171.0	COG1082@1|root,COG1082@2|Bacteria,1N8KJ@1224|Proteobacteria,42SR1@68525|delta/epsilon subdivisions,2WP5P@28221|Deltaproteobacteria,2MQKJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_125805_1	743722.Sph21_4117	7.93e-55	189.0	COG3930@1|root,COG3930@2|Bacteria,4NG5D@976|Bacteroidetes,1IUTB@117747|Sphingobacteriia	976|Bacteroidetes	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
k59_987945_1	1158165.KB898871_gene2501	1.83e-33	119.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1WYTK@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_987945_2	935840.JAEQ01000010_gene1492	4.33e-87	273.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TS6B@28211|Alphaproteobacteria,43I0X@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Trypsin-like peptidase domain	-	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
k59_439031_1	754477.Q7C_2661	1.05e-70	221.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,460CS@72273|Thiotrichales	72273|Thiotrichales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
k59_439031_2	1255043.TVNIR_1281	1.56e-11	64.7	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales	135613|Chromatiales	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_948323_1	61853.ENSNLEP00000004845	3.39e-136	385.0	KOG3205@1|root,KOG3205@2759|Eukaryota,38ETA@33154|Opisthokonta,3B9X2@33208|Metazoa,3CUAV@33213|Bilateria,480EM@7711|Chordata,48XTF@7742|Vertebrata,3J3QR@40674|Mammalia,359K9@314146|Euarchontoglires,4MARU@9443|Primates	33208|Metazoa	T	Rho GDP dissociation inhibitor (GDI) beta	ARHGDIB	GO:0003674,GO:0003824,GO:0003924,GO:0005092,GO:0005094,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0007162,GO:0007275,GO:0008150,GO:0009966,GO:0010646,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017016,GO:0017048,GO:0017111,GO:0019899,GO:0023051,GO:0030155,GO:0030234,GO:0030334,GO:0030336,GO:0030695,GO:0031267,GO:0031410,GO:0031982,GO:0032501,GO:0032502,GO:0032879,GO:0032956,GO:0032970,GO:0033043,GO:0035023,GO:0040012,GO:0040013,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043900,GO:0043901,GO:0044424,GO:0044444,GO:0044464,GO:0046578,GO:0048365,GO:0048519,GO:0048523,GO:0048583,GO:0048856,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051020,GO:0051056,GO:0051093,GO:0051128,GO:0051239,GO:0051241,GO:0051270,GO:0051271,GO:0051493,GO:0060589,GO:0065007,GO:0065009,GO:0097708,GO:0098772,GO:1901163,GO:1901164,GO:1902531,GO:2000026,GO:2000145,GO:2000146,GO:2000241,GO:2000242,GO:2000249	-	ko:K12462	ko04722,ko04962,map04722,map04962	-	-	-	ko00000,ko00001,ko04147	-	-	-	Rho_GDI
k59_752338_1	933262.AXAM01000079_gene2205	7.4e-104	304.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2WJ1Z@28221|Deltaproteobacteria,2MHWH@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_361123_2	755732.Fluta_1576	3.95e-16	77.8	COG1981@1|root,COG1981@2|Bacteria,4NEWG@976|Bacteroidetes,1HX86@117743|Flavobacteriia,2PB17@246874|Cryomorphaceae	976|Bacteroidetes	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
k59_1027149_1	376733.IT41_19665	4.06e-72	230.0	COG3547@1|root,COG3547@2|Bacteria,1Q4TE@1224|Proteobacteria,2TT7C@28211|Alphaproteobacteria,2PXXE@265|Paracoccus	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_321357_1	1049564.TevJSym_cb00050	2.16e-14	75.9	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1J6D9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_7
k59_47033_1	265072.Mfla_1111	1.39e-19	87.8	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,2KNIN@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Type II/IV secretion system protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
k59_791669_2	1049564.TevJSym_ad01550	1.53e-05	50.1	COG1463@1|root,COG1463@2|Bacteria,1QWAA@1224|Proteobacteria,1T3JS@1236|Gammaproteobacteria,1JAJH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
k59_243356_1	2340.JV46_03620	6.18e-80	252.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1J4Z9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
k59_1065988_1	1379698.RBG1_1C00001G1790	3.81e-27	112.0	COG0191@1|root,COG0191@2|Bacteria,2NPSG@2323|unclassified Bacteria	2|Bacteria	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase,OprB,SLH
k59_87117_1	1182590.BN5_03739	6.57e-95	295.0	COG2826@1|root,COG3385@1|root,COG2826@2|Bacteria,COG3385@2|Bacteria,1PQZT@1224|Proteobacteria,1TBQQ@1236|Gammaproteobacteria,1YIJZ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_1183786_1	981384.AEYW01000001_gene1602	1.5e-67	224.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_556631_1	998674.ATTE01000001_gene4346	9.35e-40	141.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,45ZTM@72273|Thiotrichales	72273|Thiotrichales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_948401_1	929556.Solca_0252	1.75e-21	96.7	COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,1IPUP@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
k59_1066018_1	259536.Psyc_0259	5.63e-12	65.9	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,3NJ14@468|Moraxellaceae	1236|Gammaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
k59_1066018_2	314287.GB2207_04442	3.36e-14	68.9	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1JAYU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
k59_439177_1	1122603.ATVI01000009_gene2612	6.95e-29	107.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_948420_1	443144.GM21_1061	1.71e-44	157.0	COG1243@1|root,COG1243@2|Bacteria,1MUYS@1224|Proteobacteria,42N2I@68525|delta/epsilon subdivisions,2WKZX@28221|Deltaproteobacteria,43TDM@69541|Desulfuromonadales	28221|Deltaproteobacteria	BK	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_C
k59_713158_1	443144.GM21_2197	1.82e-88	272.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,42N0R@68525|delta/epsilon subdivisions,2WMPF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Fer2_BFD
k59_1183855_1	1232437.KL661965_gene3260	5.71e-37	135.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
k59_713182_1	314285.KT71_03282	2.43e-10	61.2	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,1J643@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k59_206428_1	1397284.AYMN01000040_gene4390	3.08e-63	214.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,1RN40@1236|Gammaproteobacteria,3ZZU6@613|Serratia	1236|Gammaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	xdhA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	iEcHS_1320.EcHS_A3026	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_206431_1	30611.ENSOGAP00000006071	5.4e-148	434.0	COG0443@1|root,KOG0100@2759|Eukaryota,38BPF@33154|Opisthokonta,3B99M@33208|Metazoa,3CZ71@33213|Bilateria,4817Y@7711|Chordata,48WW0@7742|Vertebrata,3JA4R@40674|Mammalia,35HE6@314146|Euarchontoglires,4MA88@9443|Primates	33208|Metazoa	O	Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa)	HSPA5	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005783,GO:0005788,GO:0005789,GO:0005790,GO:0005793,GO:0005886,GO:0006355,GO:0006357,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006810,GO:0006915,GO:0006950,GO:0006983,GO:0006984,GO:0006986,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009057,GO:0009267,GO:0009314,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009719,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010042,GO:0010212,GO:0010243,GO:0010332,GO:0010466,GO:0010468,GO:0010498,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010648,GO:0010720,GO:0010941,GO:0010951,GO:0010975,GO:0010976,GO:0012501,GO:0012505,GO:0014070,GO:0014074,GO:0016020,GO:0016021,GO:0016246,GO:0016441,GO:0016458,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017015,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0019904,GO:0019941,GO:0021549,GO:0021575,GO:0021577,GO:0021587,GO:0021589,GO:0021680,GO:0021695,GO:0022008,GO:0022037,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030162,GO:0030163,GO:0030176,GO:0030182,GO:0030334,GO:0030335,GO:0030431,GO:0030433,GO:0030496,GO:0030512,GO:0030554,GO:0030902,GO:0030968,GO:0031047,GO:0031224,GO:0031227,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031344,GO:0031346,GO:0031396,GO:0031398,GO:0031399,GO:0031401,GO:0031625,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031984,GO:0032091,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032507,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032991,GO:0033036,GO:0033365,GO:0033554,GO:0034097,GO:0034613,GO:0034620,GO:0034663,GO:0034975,GO:0034976,GO:0035194,GO:0035437,GO:0035639,GO:0035690,GO:0035966,GO:0035967,GO:0036003,GO:0036094,GO:0036335,GO:0036498,GO:0036499,GO:0036500,GO:0036503,GO:0040012,GO:0040017,GO:0040019,GO:0040029,GO:0042149,GO:0042175,GO:0042220,GO:0042221,GO:0042493,GO:0042592,GO:0042594,GO:0042981,GO:0043021,GO:0043022,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043154,GO:0043161,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043279,GO:0043281,GO:0043393,GO:0043496,GO:0043618,GO:0043620,GO:0043632,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045185,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045861,GO:0045893,GO:0045935,GO:0045944,GO:0045995,GO:0046677,GO:0046683,GO:0046872,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048532,GO:0048583,GO:0048585,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048872,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051082,GO:0051087,GO:0051094,GO:0051098,GO:0051100,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051270,GO:0051272,GO:0051336,GO:0051346,GO:0051402,GO:0051591,GO:0051592,GO:0051603,GO:0051641,GO:0051651,GO:0051716,GO:0051787,GO:0051960,GO:0051962,GO:0052547,GO:0052548,GO:0060255,GO:0060284,GO:0060322,GO:0060359,GO:0060548,GO:0060904,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070670,GO:0070727,GO:0070848,GO:0070887,GO:0070972,GO:0070997,GO:0071214,GO:0071216,GO:0071236,GO:0071241,GO:0071248,GO:0071277,GO:0071287,GO:0071310,GO:0071320,GO:0071345,GO:0071353,GO:0071363,GO:0071407,GO:0071417,GO:0071478,GO:0071479,GO:0071480,GO:0071495,GO:0071496,GO:0071704,GO:0071944,GO:0072347,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0090074,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0097159,GO:0097367,GO:0097501,GO:0098827,GO:0104004,GO:0120035,GO:1900101,GO:1900102,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998,GO:1902074,GO:1902680,GO:1903320,GO:1903322,GO:1903332,GO:1903506,GO:1903508,GO:1903573,GO:1903844,GO:1903845,GO:1903891,GO:1903894,GO:1903895,GO:1903897,GO:1904313,GO:1905897,GO:1990089,GO:1990090,GO:1990440,GO:2000026,GO:2000112,GO:2000116,GO:2000117,GO:2000145,GO:2000147,GO:2001141	-	ko:K09490	ko03060,ko04141,ko04918,ko05020,map03060,map04141,map04918,map05020	-	-	-	ko00000,ko00001,ko03110,ko04131,ko04147	1.A.33	-	-	HSP70
k59_754952_1	56780.SYN_01481	9.27e-52	182.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MQZ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
k59_167375_1	439235.Dalk_3152	4.85e-51	175.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,42SHG@68525|delta/epsilon subdivisions,2WP1D@28221|Deltaproteobacteria,2MJYI@213118|Desulfobacterales	28221|Deltaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
k59_1030884_1	368407.Memar_1849	9.11e-05	50.8	COG0574@1|root,arCOG01111@2157|Archaea,2XU2T@28890|Euryarchaeota,2NAKX@224756|Methanomicrobia	224756|Methanomicrobia	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_872431_1	398512.JQKC01000019_gene3493	1.4e-30	116.0	COG1216@1|root,COG1216@2|Bacteria,1TS11@1239|Firmicutes,24BQ6@186801|Clostridia,3WIKK@541000|Ruminococcaceae	186801|Clostridia	S	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721,ko:K00786	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k59_598640_2	105559.Nwat_0841	1.25e-32	122.0	COG3637@1|root,COG3637@2|Bacteria,1R3Z1@1224|Proteobacteria,1S22U@1236|Gammaproteobacteria,1X0RX@135613|Chromatiales	135613|Chromatiales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_637623_1	545276.KB898726_gene970	1.55e-84	254.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1WWRQ@135613|Chromatiales	135613|Chromatiales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_1146825_1	865861.AZSU01000002_gene2724	4.96e-119	359.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,36DK8@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
k59_950985_1	717231.Flexsi_0751	1.95e-54	190.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,2GF1M@200930|Deferribacteres	200930|Deferribacteres	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,LUD_dom
k59_128247_1	439235.Dalk_1595	1.07e-64	212.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria,2MIJE@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM MltA	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
k59_872448_1	519989.ECTPHS_13183	1.75e-94	285.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1WWB2@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_833378_1	485918.Cpin_1337	5.97e-08	56.6	COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes,1INUV@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
k59_716580_1	1121937.AUHJ01000008_gene2000	5.57e-90	276.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,4650Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0306 Phosphate sulphate permeases	pitA	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_49930_1	84751.XP_007876972.1	8.88e-31	125.0	COG1506@1|root,KOG2100@2759|Eukaryota,39CYF@33154|Opisthokonta,3NW9P@4751|Fungi,3UZKE@5204|Basidiomycota	4751|Fungi	O	alpha beta-hydrolase	dpp5	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_755000_1	335543.Sfum_3172	5.15e-60	189.0	COG3829@1|root,COG3829@2|Bacteria,1QVJM@1224|Proteobacteria,43CC9@68525|delta/epsilon subdivisions,2X7N5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4
k59_794037_1	1121405.dsmv_1746	3.44e-45	150.0	2CC6V@1|root,3306H@2|Bacteria,1NBPY@1224|Proteobacteria,42V4A@68525|delta/epsilon subdivisions,2WS31@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_794037_2	1121405.dsmv_1747	3.3e-18	76.3	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,2MKX6@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_167425_1	335543.Sfum_0187	7.23e-65	199.0	COG0745@1|root,COG0745@2|Bacteria,1N3R6@1224|Proteobacteria,42TU3@68525|delta/epsilon subdivisions,2WQN0@28221|Deltaproteobacteria,2MRWN@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_167425_2	644282.Deba_1058	2.37e-10	60.1	COG0463@1|root,COG0463@2|Bacteria,1R547@1224|Proteobacteria,42PDC@68525|delta/epsilon subdivisions,2WKYW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
k59_598686_1	1123277.KB893174_gene5927	4.12e-14	75.1	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,Reg_prop,Y_Y_Y
k59_911463_1	439235.Dalk_2926	1.47e-67	211.0	COG1102@1|root,COG1102@2|Bacteria,1RCTZ@1224|Proteobacteria,42R0B@68525|delta/epsilon subdivisions,2WMVD@28221|Deltaproteobacteria,2MJH5@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
k59_598695_1	644966.Tmar_1720	7.86e-67	226.0	COG1139@1|root,COG1556@1|root,COG1139@2|Bacteria,COG1556@2|Bacteria,1TREQ@1239|Firmicutes,24BXS@186801|Clostridia	186801|Clostridia	C	Iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
k59_1030982_1	1121923.GPUN_2616	1.03e-32	127.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,463XX@72275|Alteromonadaceae	1236|Gammaproteobacteria	CE	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
k59_1030982_2	1367847.JCM7686_0573	3.68e-49	173.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2TR3D@28211|Alphaproteobacteria,2PV65@265|Paracoccus	28211|Alphaproteobacteria	E	Serine dehydratase beta chain	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k59_991470_1	1528106.JRJE01000001_gene2068	4.48e-35	137.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2TR1M@28211|Alphaproteobacteria,2JQMA@204441|Rhodospirillales	204441|Rhodospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SSF
k59_716618_1	984892.SPSE_1264	1.25e-08	57.4	COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,4GZ97@90964|Staphylococcaceae	91061|Bacilli	P	Rhodanese Homology Domain	yqhL	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_833425_1	9606.ENSP00000381607	4.07e-152	427.0	KOG1695@1|root,KOG1695@2759|Eukaryota,38FBQ@33154|Opisthokonta,3BDU7@33208|Metazoa,3CYE2@33213|Bilateria,481DI@7711|Chordata,496NK@7742|Vertebrata,3JCX3@40674|Mammalia,35GE3@314146|Euarchontoglires,4MAYZ@9443|Primates,4MY9S@9604|Hominidae	33208|Metazoa	O	glutathione transferase activity	GSTP1	GO:0000302,GO:0001101,GO:0001676,GO:0001775,GO:0001817,GO:0001818,GO:0001932,GO:0001933,GO:0001959,GO:0001960,GO:0002237,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002673,GO:0002674,GO:0003674,GO:0003824,GO:0004364,GO:0004601,GO:0004602,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006469,GO:0006518,GO:0006575,GO:0006629,GO:0006631,GO:0006749,GO:0006790,GO:0006805,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006955,GO:0006979,GO:0007154,GO:0007162,GO:0007275,GO:0007399,GO:0007417,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0008283,GO:0008285,GO:0008432,GO:0009058,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010001,GO:0010033,GO:0010243,GO:0010556,GO:0010558,GO:0010563,GO:0010605,GO:0010646,GO:0010648,GO:0010803,GO:0010804,GO:0010941,GO:0010942,GO:0012505,GO:0014003,GO:0014070,GO:0014910,GO:0014912,GO:0016020,GO:0016192,GO:0016209,GO:0016491,GO:0016684,GO:0016740,GO:0016765,GO:0019207,GO:0019220,GO:0019222,GO:0019752,GO:0019899,GO:0019900,GO:0019901,GO:0021782,GO:0022008,GO:0022407,GO:0022408,GO:0023051,GO:0023057,GO:0030141,GO:0030154,GO:0030155,GO:0030234,GO:0030334,GO:0030336,GO:0031099,GO:0031100,GO:0031323,GO:0031324,GO:0031325,GO:0031347,GO:0031348,GO:0031399,GO:0031400,GO:0031410,GO:0031667,GO:0031668,GO:0031960,GO:0031974,GO:0031982,GO:0031983,GO:0032101,GO:0032102,GO:0032268,GO:0032269,GO:0032355,GO:0032496,GO:0032501,GO:0032502,GO:0032642,GO:0032651,GO:0032652,GO:0032680,GO:0032682,GO:0032691,GO:0032692,GO:0032720,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0032872,GO:0032873,GO:0032879,GO:0032928,GO:0032930,GO:0032940,GO:0032991,GO:0033218,GO:0033273,GO:0033483,GO:0033484,GO:0033559,GO:0033591,GO:0033673,GO:0033993,GO:0034284,GO:0034641,GO:0034774,GO:0035726,GO:0035730,GO:0035731,GO:0035732,GO:0036230,GO:0040012,GO:0040013,GO:0042063,GO:0042119,GO:0042127,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042493,GO:0042592,GO:0042742,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043122,GO:0043124,GO:0043167,GO:0043168,GO:0043200,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043295,GO:0043299,GO:0043312,GO:0043405,GO:0043407,GO:0043408,GO:0043409,GO:0043434,GO:0043436,GO:0043506,GO:0043508,GO:0043549,GO:0043603,GO:0043651,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045087,GO:0045321,GO:0045471,GO:0045859,GO:0045936,GO:0046328,GO:0046329,GO:0046677,GO:0046903,GO:0048037,GO:0048145,GO:0048147,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0048660,GO:0048662,GO:0048709,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050727,GO:0050728,GO:0050789,GO:0050790,GO:0050794,GO:0050829,GO:0050896,GO:0050920,GO:0050922,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051248,GO:0051270,GO:0051271,GO:0051338,GO:0051341,GO:0051348,GO:0051354,GO:0051384,GO:0051704,GO:0051707,GO:0051716,GO:0051769,GO:0051771,GO:0055114,GO:0060205,GO:0060255,GO:0060548,GO:0060759,GO:0060761,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070026,GO:0070302,GO:0070303,GO:0070372,GO:0070373,GO:0070663,GO:0070664,GO:0070848,GO:0070849,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071363,GO:0071364,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071460,GO:0071466,GO:0071495,GO:0071496,GO:0071637,GO:0071638,GO:0071671,GO:0071672,GO:0071704,GO:0071900,GO:0071901,GO:0071944,GO:0072341,GO:0080090,GO:0080134,GO:0080135,GO:0090322,GO:0097057,GO:0097237,GO:0097305,GO:0097708,GO:0098542,GO:0098754,GO:0098772,GO:0098869,GO:0099503,GO:0101002,GO:1900750,GO:1901214,GO:1901215,GO:1901216,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901681,GO:1901685,GO:1901687,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902532,GO:1903037,GO:1903038,GO:1903555,GO:1903556,GO:1904705,GO:1904706,GO:1904813,GO:1905802,GO:1905803,GO:1905804,GO:1990748,GO:2000145,GO:2000146,GO:2000377,GO:2000379,GO:2000428,GO:2000429,GO:2000468,GO:2000469,GO:2001233,GO:2001234,GO:2001236,GO:2001237	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_3,GST_N
k59_403137_1	1121405.dsmv_1353	2.42e-37	135.0	COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WMNG@28221|Deltaproteobacteria,2MPW9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
k59_951054_2	1163389.OOM_0534	3.26e-67	208.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,1RN32@1236|Gammaproteobacteria,460DI@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
k59_1208759_2	399795.CtesDRAFT_PD5090	1.87e-14	73.6	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,4AA59@80864|Comamonadaceae	28216|Betaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_1089728_1	185453.XP_006877391.1	4.94e-142	401.0	COG0049@1|root,KOG3291@2759|Eukaryota,38GCC@33154|Opisthokonta,3BHSW@33208|Metazoa,3CTFG@33213|Bilateria,48074@7711|Chordata,4922F@7742|Vertebrata,3JDMA@40674|Mammalia,3555T@311790|Afrotheria	33208|Metazoa	J	40S ribosomal protein	RPS5	GO:0000028,GO:0000184,GO:0000956,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006450,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031974,GO:0031981,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034655,GO:0042254,GO:0042255,GO:0042274,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0050789,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0070925,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071826,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02989	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_737782_1	1125863.JAFN01000001_gene76	2.16e-57	197.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_1208765_1	395493.BegalDRAFT_0478	8.26e-33	122.0	COG4968@1|root,COG4968@2|Bacteria,1QUZW@1224|Proteobacteria,1T31D@1236|Gammaproteobacteria,463V3@72273|Thiotrichales	72273|Thiotrichales	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
k59_545705_1	1279019.ARQK01000050_gene1285	3.59e-78	256.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales	135613|Chromatiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_32319_1	1112216.JH594425_gene2405	1.42e-08	55.1	COG0317@1|root,COG0317@2|Bacteria,1RKVU@1224|Proteobacteria,2VGQH@28211|Alphaproteobacteria,2K8TF@204457|Sphingomonadales	204457|Sphingomonadales	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
k59_32319_2	90814.KL370891_gene615	2.13e-24	98.6	2C3VI@1|root,33N3E@2|Bacteria,1NESF@1224|Proteobacteria,1STIY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_503128_1	857087.Metme_0076	1.2e-18	79.7	COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,1SC8R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_346751_1	1336235.JAEG01000006_gene914	6.74e-51	174.0	COG0687@1|root,COG0687@2|Bacteria,1PRWU@1224|Proteobacteria,2U2MI@28211|Alphaproteobacteria,4BJ9U@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
k59_1208789_1	1029824.AFID01000004_gene499	3.26e-17	88.6	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,1W8GA@1268|Micrococcaceae	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_658657_1	589865.DaAHT2_0263	1.4e-71	237.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42QM3@68525|delta/epsilon subdivisions,2WKI2@28221|Deltaproteobacteria,2MI4S@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
k59_814849_1	1218076.BAYB01000024_gene4178	2.77e-66	213.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,1JZZI@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
k59_463560_1	472759.Nhal_3328	1.13e-27	108.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1WXFS@135613|Chromatiales	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_463560_2	1408424.JHYI01000004_gene3471	3.43e-09	61.2	COG0438@1|root,COG1543@1|root,COG0438@2|Bacteria,COG1543@2|Bacteria,1TPFX@1239|Firmicutes,4HD14@91061|Bacilli,1ZPVT@1386|Bacillus	91061|Bacilli	M	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_737814_1	765912.Thimo_2522	1.7e-63	208.0	2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,1RSN5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1208808_1	1125863.JAFN01000001_gene583	6.64e-89	270.0	COG1893@1|root,COG1893@2|Bacteria,1R96Z@1224|Proteobacteria,42PU0@68525|delta/epsilon subdivisions,2WK47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_71121_1	1232437.KL662020_gene705	5.46e-108	326.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_658708_1	177439.DP0903	5.92e-46	162.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2MJ7G@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
k59_658708_2	1198114.AciX9_2909	1.09e-22	96.3	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,3Y2I9@57723|Acidobacteria,2JHNT@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_1169511_1	706587.Desti_4208	5.36e-27	114.0	COG3852@1|root,COG5000@1|root,COG3852@2|Bacteria,COG5000@2|Bacteria,1R1JU@1224|Proteobacteria,43DA4@68525|delta/epsilon subdivisions,2X8GR@28221|Deltaproteobacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	regM	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
k59_113653_1	622637.KE124774_gene2177	4.02e-66	206.0	COG3415@1|root,COG3415@2|Bacteria,1RDMQ@1224|Proteobacteria,2U7PU@28211|Alphaproteobacteria,36ZBE@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32,HTH_33
k59_113653_2	348824.LPU83_pLPU83a_0068	1.28e-53	173.0	COG3335@1|root,COG3335@2|Bacteria,1RB1C@1224|Proteobacteria,2U367@28211|Alphaproteobacteria,4BC4T@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	protein y4pE y4sA	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_390051_1	247490.KSU1_D0158	7.11e-64	211.0	COG3666@1|root,COG3666@2|Bacteria,2J1Y1@203682|Planctomycetes	203682|Planctomycetes	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_191389_1	9593.ENSGGOP00000023616	9.78e-89	271.0	2CV1G@1|root,2RQEK@2759|Eukaryota,39XY0@33154|Opisthokonta,3BNS8@33208|Metazoa,3D1TZ@33213|Bilateria,483A8@7711|Chordata,48V6P@7742|Vertebrata,3JD16@40674|Mammalia,35BEG@314146|Euarchontoglires,4MCGE@9443|Primates,4N4XT@9604|Hominidae	33208|Metazoa	W	antigen processing and presentation of peptide antigen via MHC class I	HLA-C	GO:0000139,GO:0001775,GO:0001817,GO:0001910,GO:0001911,GO:0001912,GO:0001914,GO:0001916,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002474,GO:0002478,GO:0002479,GO:0002480,GO:0002483,GO:0002484,GO:0002486,GO:0002643,GO:0002664,GO:0002667,GO:0002682,GO:0002683,GO:0002684,GO:0002697,GO:0002698,GO:0002699,GO:0002703,GO:0002704,GO:0002705,GO:0002706,GO:0002707,GO:0002708,GO:0002709,GO:0002711,GO:0002715,GO:0002716,GO:0002819,GO:0002821,GO:0002822,GO:0002824,GO:0002911,GO:0003674,GO:0003823,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005783,GO:0005789,GO:0005794,GO:0005798,GO:0005886,GO:0005887,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006955,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0009595,GO:0009605,GO:0009607,GO:0009617,GO:0009986,GO:0009987,GO:0010008,GO:0010033,GO:0012505,GO:0012506,GO:0012507,GO:0016020,GO:0016021,GO:0016045,GO:0016192,GO:0019221,GO:0019882,GO:0019883,GO:0019884,GO:0019885,GO:0023052,GO:0030133,GO:0030134,GO:0030135,GO:0030139,GO:0030141,GO:0030176,GO:0030658,GO:0030659,GO:0030660,GO:0030662,GO:0030666,GO:0030667,GO:0030670,GO:0031090,GO:0031224,GO:0031226,GO:0031227,GO:0031341,GO:0031342,GO:0031343,GO:0031347,GO:0031348,GO:0031410,GO:0031901,GO:0031982,GO:0031984,GO:0032655,GO:0032675,GO:0032940,GO:0032991,GO:0033218,GO:0034097,GO:0034340,GO:0034341,GO:0036230,GO:0042119,GO:0042175,GO:0042221,GO:0042269,GO:0042270,GO:0042277,GO:0042590,GO:0042605,GO:0042611,GO:0042612,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043299,GO:0043312,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045055,GO:0045087,GO:0045088,GO:0045321,GO:0045335,GO:0045595,GO:0045824,GO:0045953,GO:0046903,GO:0046977,GO:0048002,GO:0048518,GO:0048519,GO:0048583,GO:0048584,GO:0048585,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051087,GO:0051179,GO:0051234,GO:0051239,GO:0051606,GO:0051704,GO:0051707,GO:0051716,GO:0055037,GO:0055038,GO:0060333,GO:0060337,GO:0065007,GO:0070887,GO:0071310,GO:0071345,GO:0071346,GO:0071357,GO:0071556,GO:0071944,GO:0080134,GO:0097708,GO:0098543,GO:0098552,GO:0098553,GO:0098581,GO:0098588,GO:0098791,GO:0098796,GO:0098797,GO:0098805,GO:0098827,GO:0099503,GO:1902105,GO:1903706,GO:2000026,GO:2001198	2.3.2.27	ko:K06751,ko:K12015	ko04144,ko04145,ko04218,ko04514,ko04612,ko04940,ko05165,ko05166,ko05167,ko05168,ko05169,ko05203,ko05320,ko05330,ko05332,ko05416,map04144,map04145,map04218,map04514,map04612,map04940,map05165,map05166,map05167,map05168,map05169,map05203,map05320,map05330,map05332,map05416	-	-	-	ko00000,ko00001,ko00537,ko01000,ko04121,ko04147,ko04516	-	-	-	C1-set,MHC_I,MHC_I_C
k59_977184_1	519989.ECTPHS_05435	4.1e-74	235.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1WX7U@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
k59_858172_1	1329516.JPST01000015_gene768	1.8e-70	222.0	COG2043@1|root,COG2043@2|Bacteria,1TT5P@1239|Firmicutes,4HFED@91061|Bacilli	91061|Bacilli	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
k59_191435_1	1185766.DL1_02415	4.13e-37	140.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2TR64@28211|Alphaproteobacteria,2XM2R@285107|Thioclava	28211|Alphaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_701801_1	1380391.JIAS01000019_gene1321	1.21e-20	92.8	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria,2JQEE@204441|Rhodospirillales	204441|Rhodospirillales	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
k59_701801_2	1317122.ATO12_06925	6.82e-20	87.4	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1HYIB@117743|Flavobacteriia,2YGXZ@290174|Aquimarina	976|Bacteroidetes	E	Arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_701802_1	1265505.ATUG01000002_gene1612	5e-49	172.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKB1@28221|Deltaproteobacteria,2MIJB@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_191444_1	59538.XP_005960803.1	3.03e-98	286.0	KOG3158@1|root,KOG3158@2759|Eukaryota,3A1J4@33154|Opisthokonta,3BAQK@33208|Metazoa,3CYPV@33213|Bilateria,48365@7711|Chordata,48ZDK@7742|Vertebrata,3JB9I@40674|Mammalia,4J426@91561|Cetartiodactyla	33208|Metazoa	O	Prostaglandin E synthase 3	PTGES3	GO:0000271,GO:0000723,GO:0000781,GO:0001516,GO:0001676,GO:0002039,GO:0003008,GO:0003674,GO:0003720,GO:0003824,GO:0003964,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005697,GO:0005737,GO:0005829,GO:0005856,GO:0005884,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006082,GO:0006091,GO:0006112,GO:0006139,GO:0006259,GO:0006278,GO:0006457,GO:0006458,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0006725,GO:0006805,GO:0006807,GO:0006996,GO:0007004,GO:0007154,GO:0007165,GO:0007275,GO:0007600,GO:0008150,GO:0008152,GO:0008283,GO:0008610,GO:0009058,GO:0009059,GO:0009250,GO:0009410,GO:0009719,GO:0009725,GO:0009755,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010604,GO:0010628,GO:0010833,GO:0010941,GO:0014070,GO:0015629,GO:0015980,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016853,GO:0016860,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019233,GO:0019369,GO:0019371,GO:0019438,GO:0019752,GO:0019899,GO:0022607,GO:0022613,GO:0022618,GO:0023052,GO:0030323,GO:0030324,GO:0030518,GO:0030522,GO:0031072,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031647,GO:0031958,GO:0031974,GO:0031981,GO:0032200,GO:0032501,GO:0032502,GO:0032787,GO:0032870,GO:0032991,GO:0033559,GO:0033692,GO:0033993,GO:0034061,GO:0034622,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0035295,GO:0036477,GO:0042221,GO:0042325,GO:0042327,GO:0042592,GO:0042921,GO:0042995,GO:0043005,GO:0043025,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043401,GO:0043436,GO:0043588,GO:0043933,GO:0044042,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0045935,GO:0045937,GO:0046394,GO:0046456,GO:0046457,GO:0046483,GO:0048286,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048731,GO:0048856,GO:0050220,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050877,GO:0050896,GO:0051052,GO:0051054,GO:0051082,GO:0051084,GO:0051085,GO:0051131,GO:0051171,GO:0051173,GO:0051174,GO:0051276,GO:0051338,GO:0051347,GO:0051716,GO:0051879,GO:0051972,GO:0051973,GO:0055114,GO:0060249,GO:0060255,GO:0060430,GO:0060541,GO:0060548,GO:0061077,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070182,GO:0070887,GO:0071310,GO:0071383,GO:0071396,GO:0071407,GO:0071466,GO:0071495,GO:0071704,GO:0071826,GO:0071840,GO:0071897,GO:0072330,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097458,GO:0098687,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0101031,GO:0120025,GO:0140097,GO:1900034,GO:1901360,GO:1901362,GO:1901568,GO:1901570,GO:1901576,GO:1905323,GO:1990904,GO:2000112,GO:2000278,GO:2000573	5.3.99.3	ko:K15730	ko00590,ko01100,map00590,map01100	-	R02265	RC00672	ko00000,ko00001,ko01000	-	-	-	CS
k59_898048_1	177439.DP1889	2.44e-45	166.0	COG2208@1|root,COG3850@1|root,COG2208@2|Bacteria,COG3850@2|Bacteria,1R7WZ@1224|Proteobacteria,42Q3R@68525|delta/epsilon subdivisions,2WM5A@28221|Deltaproteobacteria,2MIDF@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SSF,SpoIIE
k59_35337_1	648757.Rvan_0651	1.15e-95	304.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,3N67P@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_740822_1	204669.Acid345_0948	4.72e-66	218.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,3Y578@57723|Acidobacteria,2JKKV@204432|Acidobacteriia	204432|Acidobacteriia	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
k59_935810_1	1307759.JOMJ01000003_gene1875	4.15e-51	169.0	COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,42W4J@68525|delta/epsilon subdivisions,2WRJC@28221|Deltaproteobacteria,2MCIS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
k59_1092758_1	1049564.TevJSym_aa00750	1.05e-16	84.3	COG1270@1|root,COG1270@2|Bacteria	2|Bacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
k59_1092758_2	523791.Kkor_0701	5.12e-35	125.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1XJIY@135619|Oceanospirillales	135619|Oceanospirillales	V	Negative regulator of beta-lactamase expression	ampD	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
k59_1092767_1	335543.Sfum_3644	6.49e-110	329.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2WJB8@28221|Deltaproteobacteria,2MQ7D@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_234425_1	1342299.Z947_85	2.31e-90	277.0	COG1638@1|root,COG1638@2|Bacteria,1R7GB@1224|Proteobacteria,2U0ZQ@28211|Alphaproteobacteria,3ZVPE@60136|Sulfitobacter	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_35376_1	880072.Desac_2591	1.3e-66	216.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42P53@68525|delta/epsilon subdivisions,2WJ2U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
k59_584576_1	61853.ENSNLEP00000004858	1.15e-107	336.0	COG1501@1|root,KOG1066@2759|Eukaryota,3AJSB@33154|Opisthokonta,3BDJ3@33208|Metazoa,3CRKP@33213|Bilateria,4800W@7711|Chordata,490EW@7742|Vertebrata,3JERC@40674|Mammalia,35D8I@314146|Euarchontoglires,4M7Z7@9443|Primates	33208|Metazoa	G	Belongs to the glycosyl hydrolase 31 family	GANAB	GO:0000272,GO:0000323,GO:0003674,GO:0003824,GO:0004553,GO:0004558,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005783,GO:0005788,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0006491,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009100,GO:0009251,GO:0009987,GO:0012505,GO:0015926,GO:0015980,GO:0016052,GO:0016787,GO:0016798,GO:0017177,GO:0019538,GO:0031974,GO:0032991,GO:0033919,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0055114,GO:0070013,GO:0071704,GO:0090599,GO:0090600,GO:1901135,GO:1901564,GO:1901575	3.2.1.20,3.2.1.84	ko:K05546,ko:K12317	ko00052,ko00500,ko00510,ko01100,ko04141,map00052,map00500,map00510,map01100,map04141	M00073,M00074	R00028,R00801,R00802,R05980,R05981	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000	-	GH31	-	DUF5110,Gal_mutarotas_2,Glyco_hydro_31
k59_740870_1	1125863.JAFN01000001_gene744	1.81e-56	187.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2WJDQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the HypD family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
k59_661693_2	1121015.N789_09680	1.7e-39	144.0	COG1988@1|root,COG1988@2|Bacteria,1QK5N@1224|Proteobacteria,1S0MU@1236|Gammaproteobacteria,1X507@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
k59_73969_1	69279.BG36_09860	5.99e-45	163.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,43HRF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	ABC-type multidrug transport system ATPase and permease	abcT3	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
k59_977272_1	1118235.CAJH01000044_gene2815	1.27e-05	51.2	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RZA4@1236|Gammaproteobacteria,1X7KS@135614|Xanthomonadales	135614|Xanthomonadales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_390204_1	879212.DespoDRAFT_01391	1.2e-161	466.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2MHPF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k59_977292_1	1192868.CAIU01000006_gene571	5.36e-82	262.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,43IHT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	Methylmalonyl-CoA mutase	bhbA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
k59_624194_1	335543.Sfum_1614	6.07e-81	254.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,42N7R@68525|delta/epsilon subdivisions,2WJBI@28221|Deltaproteobacteria,2MR3A@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k59_858277_1	1028801.RG1141_PA09380	2.36e-18	88.2	COG3713@1|root,COG3713@2|Bacteria,1N0BC@1224|Proteobacteria,2U7QE@28211|Alphaproteobacteria,4B79S@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	MltA-interacting protein MipA	-	-	-	-	-	-	-	-	-	-	-	-	MipA
k59_506149_1	391615.ABSJ01000039_gene1801	4.89e-72	224.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1J4MF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_506149_2	323261.Noc_1633	3.39e-48	163.0	COG2022@1|root,COG2104@1|root,COG2022@2|Bacteria,COG2104@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,1WW65@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
k59_977320_1	697282.Mettu_1619	2.74e-106	318.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,1XEHS@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
k59_152444_2	395964.KE386496_gene2517	2e-57	184.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,3NAZX@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Putative zinc- or iron-chelating domain	MA20_15575	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_152444_3	420324.KI911965_gene734	1.81e-10	60.5	COG0778@1|root,COG0778@2|Bacteria,1MY39@1224|Proteobacteria,2TTZC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0778 Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_898190_1	648885.KB316282_gene75	2.91e-63	214.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2TRCK@28211|Alphaproteobacteria,1JRCG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	dcp	GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_780305_1	1499967.BAYZ01000078_gene985	4.99e-146	425.0	COG1541@1|root,COG1541@2|Bacteria,2NREC@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_817911_1	96561.Dole_2959	5.64e-63	205.0	2CFUQ@1|root,2ZC1I@2|Bacteria,1RBHI@1224|Proteobacteria,42QR4@68525|delta/epsilon subdivisions,2WMXI@28221|Deltaproteobacteria,2MJQJ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1172635_1	335543.Sfum_1697	2.32e-41	142.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WNMC@28221|Deltaproteobacteria,2MQPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
k59_271811_1	105559.Nwat_3012	7.45e-104	331.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WWNH@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_152476_1	27679.XP_010337720.1	7.22e-121	348.0	KOG4387@1|root,KOG4387@2759|Eukaryota,38HH6@33154|Opisthokonta,3BI34@33208|Metazoa,3CSYR@33213|Bilateria,4865F@7711|Chordata,48YXK@7742|Vertebrata,3J8RW@40674|Mammalia,35KVN@314146|Euarchontoglires,4M9GT@9443|Primates	33208|Metazoa	E	Ornithine decarboxylase antizyme	OAZ1	GO:0003674,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006521,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010565,GO:0010604,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0032386,GO:0032388,GO:0032879,GO:0032880,GO:0033157,GO:0033238,GO:0034641,GO:0034762,GO:0034763,GO:0042176,GO:0042401,GO:0042979,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044092,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0046982,GO:0046983,GO:0048518,GO:0048519,GO:0050789,GO:0050790,GO:0050794,GO:0051049,GO:0051050,GO:0051051,GO:0051171,GO:0051173,GO:0051222,GO:0051223,GO:0051246,GO:0051247,GO:0060255,GO:0060341,GO:0062012,GO:0065007,GO:0065009,GO:0070201,GO:0071704,GO:0080090,GO:0090087,GO:0090316,GO:0098772,GO:1901564,GO:1901566,GO:1901576,GO:1902267,GO:1902268,GO:1903827,GO:1903829,GO:1904951	-	ko:K16548,ko:K16613	-	-	-	-	ko00000,ko03036	-	-	-	ODC_AZ
k59_74063_1	1278307.KB906974_gene1806	1.38e-08	59.7	COG0642@1|root,COG0834@1|root,COG4251@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2QIRM@267894|Psychromonadaceae	1236|Gammaproteobacteria	T	ATP-binding region, ATPase domain protein domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	CHASE,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
k59_74063_2	944547.ABLL_1633	3.15e-12	66.2	COG0834@1|root,COG2202@1|root,COG4191@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42R1U@68525|delta/epsilon subdivisions,2YNX6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_9
k59_191643_2	990285.RGCCGE502_15935	2.25e-35	130.0	COG3842@1|root,COG3842@2|Bacteria,1QYZ3@1224|Proteobacteria,2TT89@28211|Alphaproteobacteria,4B9C9@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the ABC transporter superfamily	smoK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
k59_74082_1	158500.BV97_05755	2.47e-42	155.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,2VGSR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_310558_1	266835.14025229	1.4e-79	262.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,43IB9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the GcvT family	Sardh	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k59_661845_1	941449.dsx2_1628	1.16e-65	223.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1QFX3@1224|Proteobacteria,42PIP@68525|delta/epsilon subdivisions,2WKWI@28221|Deltaproteobacteria,2MG9J@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Pyruvate phosphate dikinase, PEP pyruvate-binding	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_271850_1	556268.OFAG_00255	2.75e-06	49.7	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,473P9@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_271850_2	713586.KB900536_gene2891	1.46e-63	202.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,1S2TG@1236|Gammaproteobacteria,1X0P8@135613|Chromatiales	135613|Chromatiales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_1172709_1	396595.TK90_2199	1.18e-75	236.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1WW8T@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k59_1092930_1	1121022.ABENE_21950	5.23e-77	240.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TSGZ@28211|Alphaproteobacteria,2KHQT@204458|Caulobacterales	204458|Caulobacterales	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_116727_1	1232437.KL662006_gene4353	4.94e-38	137.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria,2MITB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_1212006_1	1341151.ASZU01000008_gene1512	4.26e-42	147.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,27B6H@186824|Thermoactinomycetaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_584778_2	396588.Tgr7_2693	8.74e-54	173.0	2AEMZ@1|root,314HW@2|Bacteria,1RHE3@1224|Proteobacteria,1S7P7@1236|Gammaproteobacteria,1WYF1@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_390311_1	621372.ACIH01000008_gene509	1.49e-05	53.1	COG1649@1|root,COG2755@1|root,COG1649@2|Bacteria,COG2755@2|Bacteria,1VSSI@1239|Firmicutes,4HWAN@91061|Bacilli,26V6I@186822|Paenibacillaceae	91061|Bacilli	E	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	DUF4985,GHL10,SLH
k59_271879_1	157072.XP_008863487.1	3.34e-21	96.7	COG1024@1|root,KOG1684@2759|Eukaryota	2759|Eukaryota	I	3-hydroxyisobutyryl-CoA hydrolase activity	-	GO:0003674,GO:0003824,GO:0003860,GO:0016289,GO:0016787,GO:0016788,GO:0016790	3.1.2.4	ko:K05605	ko00280,ko00410,ko00640,ko01100,ko01200,map00280,map00410,map00640,map01100,map01200	M00013	R03158,R05064	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_2
k59_271880_1	511062.GU3_03455	4.81e-28	105.0	COG3474@1|root,COG3474@2|Bacteria,1N0PG@1224|Proteobacteria,1S8YS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_271880_2	1397528.Q671_06795	3.49e-63	205.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,1XICY@135619|Oceanospirillales	135619|Oceanospirillales	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
k59_858429_1	177437.HRM2_44770	1.96e-53	177.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_1092987_1	457421.CBFG_00876	5.18e-15	80.1	COG0491@1|root,COG0491@2|Bacteria,1TX4N@1239|Firmicutes,24A0N@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd,Lactamase_B
k59_1172764_1	1340493.JNIF01000004_gene100	3.21e-26	105.0	COG0061@1|root,COG0061@2|Bacteria,3Y3E6@57723|Acidobacteria	57723|Acidobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_741140_1	314282.PCNPT3_05185	6.57e-22	93.2	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,2QHUI@267894|Psychromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475	TGT
k59_1231110_1	1303518.CCALI_00132	5.63e-23	100.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_1150319_1	1121396.KB892913_gene116	3e-49	173.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42WI2@68525|delta/epsilon subdivisions,2WRPD@28221|Deltaproteobacteria,2MQ18@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_1111353_2	1121935.AQXX01000122_gene5633	6.51e-09	56.2	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XH7Y@135619|Oceanospirillales	135619|Oceanospirillales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_876067_1	883080.HMPREF9697_03877	8.59e-17	83.6	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2TTP3@28211|Alphaproteobacteria,3JR3H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_719922_1	225937.HP15_2647	3.32e-45	163.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,1RQR7@1236|Gammaproteobacteria,4668G@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
k59_1111379_1	653045.Strvi_6765	2.38e-19	87.4	COG1834@1|root,COG1834@2|Bacteria,2GNTN@201174|Actinobacteria	201174|Actinobacteria	E	amidinotransferase	ddaH	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
k59_1189842_1	9986.ENSOCUP00000018598	2.66e-171	480.0	COG0092@1|root,KOG3181@2759|Eukaryota,38CWQ@33154|Opisthokonta,3BI4I@33208|Metazoa,3CRZZ@33213|Bilateria,4840Y@7711|Chordata,48YGW@7742|Vertebrata,3JB98@40674|Mammalia,35GRU@314146|Euarchontoglires	33208|Metazoa	J	positive regulation of DNA N-glycosylase activity	RPS3	GO:0000184,GO:0000226,GO:0000302,GO:0000702,GO:0000956,GO:0001726,GO:0001817,GO:0001819,GO:0001932,GO:0001934,GO:0002181,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003723,GO:0003729,GO:0003735,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005783,GO:0005789,GO:0005791,GO:0005819,GO:0005829,GO:0005840,GO:0005844,GO:0005856,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006282,GO:0006355,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006417,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006950,GO:0006974,GO:0006979,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007059,GO:0008017,GO:0008092,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008284,GO:0008534,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009636,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010638,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012505,GO:0015031,GO:0015630,GO:0015631,GO:0015833,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0016363,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0016829,GO:0016835,GO:0017148,GO:0019104,GO:0019219,GO:0019220,GO:0019222,GO:0019439,GO:0019538,GO:0019843,GO:0019866,GO:0019899,GO:0019900,GO:0019901,GO:0022402,GO:0022407,GO:0022409,GO:0022607,GO:0022626,GO:0022627,GO:0023051,GO:0023056,GO:0030155,GO:0030162,GO:0030425,GO:0030544,GO:0030867,GO:0031072,GO:0031090,GO:0031110,GO:0031112,GO:0031113,GO:0031116,GO:0031252,GO:0031253,GO:0031256,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031334,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0031984,GO:0032069,GO:0032070,GO:0032071,GO:0032075,GO:0032077,GO:0032079,GO:0032268,GO:0032269,GO:0032270,GO:0032271,GO:0032273,GO:0032356,GO:0032357,GO:0032358,GO:0032587,GO:0032663,GO:0032743,GO:0032872,GO:0032874,GO:0032886,GO:0032944,GO:0032946,GO:0032991,GO:0033036,GO:0033043,GO:0033365,GO:0033554,GO:0033674,GO:0034097,GO:0034248,GO:0034249,GO:0034399,GO:0034599,GO:0034612,GO:0034613,GO:0034614,GO:0034641,GO:0034645,GO:0034655,GO:0035690,GO:0036477,GO:0042102,GO:0042104,GO:0042127,GO:0042129,GO:0042175,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042542,GO:0042769,GO:0042886,GO:0042981,GO:0042995,GO:0043005,GO:0043043,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043280,GO:0043281,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043506,GO:0043507,GO:0043523,GO:0043524,GO:0043549,GO:0043603,GO:0043604,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044390,GO:0044391,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044430,GO:0044432,GO:0044444,GO:0044445,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045047,GO:0045184,GO:0045738,GO:0045739,GO:0045785,GO:0045859,GO:0045860,GO:0045862,GO:0045934,GO:0045935,GO:0045937,GO:0046006,GO:0046328,GO:0046330,GO:0046483,GO:0046677,GO:0046700,GO:0046907,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050670,GO:0050671,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050854,GO:0050856,GO:0050857,GO:0050862,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051018,GO:0051052,GO:0051053,GO:0051054,GO:0051090,GO:0051091,GO:0051092,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051225,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051251,GO:0051252,GO:0051336,GO:0051338,GO:0051345,GO:0051347,GO:0051493,GO:0051495,GO:0051536,GO:0051540,GO:0051606,GO:0051641,GO:0051649,GO:0051716,GO:0051879,GO:0052547,GO:0052548,GO:0060255,GO:0060548,GO:0061481,GO:0065007,GO:0065009,GO:0070013,GO:0070181,GO:0070301,GO:0070302,GO:0070304,GO:0070507,GO:0070663,GO:0070665,GO:0070727,GO:0070848,GO:0070887,GO:0070925,GO:0070972,GO:0071159,GO:0071236,GO:0071310,GO:0071345,GO:0071356,GO:0071363,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0072686,GO:0080090,GO:0080134,GO:0080135,GO:0090150,GO:0090304,GO:0090305,GO:0097100,GO:0097159,GO:0097237,GO:0097447,GO:0097458,GO:0098552,GO:0098554,GO:0098556,GO:0098562,GO:0098588,GO:0098590,GO:0098827,GO:0120025,GO:0120038,GO:0140078,GO:0140097,GO:1900117,GO:1900119,GO:1901214,GO:1901215,GO:1901222,GO:1901224,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901700,GO:1901701,GO:1902229,GO:1902231,GO:1902531,GO:1902533,GO:1902544,GO:1902546,GO:1902903,GO:1902905,GO:1903037,GO:1903039,GO:1903320,GO:1903321,GO:1903506,GO:1905051,GO:1905053,GO:1990089,GO:1990090,GO:1990904,GO:2000112,GO:2000113,GO:2000116,GO:2001020,GO:2001021,GO:2001022,GO:2001056,GO:2001141,GO:2001233,GO:2001235,GO:2001242,GO:2001244,GO:2001270,GO:2001272	-	ko:K02985	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
k59_1035652_1	30611.ENSOGAP00000005496	6.12e-124	377.0	COG5215@1|root,KOG1241@2759|Eukaryota,38HCJ@33154|Opisthokonta,3BA50@33208|Metazoa,3CUGE@33213|Bilateria,483E8@7711|Chordata,493P4@7742|Vertebrata,3J9U3@40674|Mammalia,35NZ3@314146|Euarchontoglires,4MAFQ@9443|Primates	33208|Metazoa	UY	Karyopherin (importin) beta 1	KPNB1	GO:0000003,GO:0000060,GO:0000070,GO:0000226,GO:0000278,GO:0000280,GO:0000737,GO:0000819,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005643,GO:0005654,GO:0005737,GO:0005783,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006309,GO:0006606,GO:0006607,GO:0006610,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006887,GO:0006913,GO:0006915,GO:0006921,GO:0006928,GO:0006955,GO:0006996,GO:0007010,GO:0007017,GO:0007018,GO:0007049,GO:0007051,GO:0007052,GO:0007059,GO:0007079,GO:0007080,GO:0007154,GO:0007165,GO:0007264,GO:0007265,GO:0007275,GO:0008092,GO:0008104,GO:0008139,GO:0008150,GO:0008152,GO:0008219,GO:0008270,GO:0008565,GO:0009056,GO:0009057,GO:0009790,GO:0009792,GO:0009889,GO:0009987,GO:0010494,GO:0012501,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016032,GO:0016043,GO:0016192,GO:0017038,GO:0019048,GO:0019054,GO:0019058,GO:0019216,GO:0019218,GO:0019222,GO:0019439,GO:0019894,GO:0019899,GO:0019904,GO:0022402,GO:0022411,GO:0022607,GO:0023052,GO:0030141,GO:0030262,GO:0030953,GO:0031072,GO:0031090,GO:0031122,GO:0031291,GO:0031410,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0031982,GO:0031983,GO:0031984,GO:0032501,GO:0032502,GO:0032940,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034399,GO:0034504,GO:0034613,GO:0034641,GO:0034655,GO:0034774,GO:0035556,GO:0035580,GO:0035770,GO:0035821,GO:0036230,GO:0036464,GO:0040001,GO:0042119,GO:0042277,GO:0042581,GO:0042886,GO:0043167,GO:0043169,GO:0043170,GO:0043186,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0044003,GO:0044068,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0044766,GO:0044877,GO:0045055,GO:0045184,GO:0045321,GO:0045495,GO:0045540,GO:0046483,GO:0046700,GO:0046794,GO:0046872,GO:0046890,GO:0046903,GO:0046907,GO:0046914,GO:0048285,GO:0048856,GO:0050000,GO:0050789,GO:0050794,GO:0050810,GO:0050896,GO:0051169,GO:0051170,GO:0051179,GO:0051225,GO:0051234,GO:0051276,GO:0051293,GO:0051303,GO:0051305,GO:0051310,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0051701,GO:0051704,GO:0051716,GO:0051817,GO:0051879,GO:0060205,GO:0060293,GO:0062012,GO:0065007,GO:0070013,GO:0070727,GO:0070925,GO:0071702,GO:0071704,GO:0071705,GO:0071782,GO:0071840,GO:0072594,GO:0075733,GO:0080090,GO:0090181,GO:0090304,GO:0090305,GO:0090307,GO:0097194,GO:0097435,GO:0097708,GO:0098813,GO:0098827,GO:0099503,GO:0101002,GO:0106118,GO:0140014,GO:1901360,GO:1901361,GO:1901575,GO:1902579,GO:1902850,GO:1902930,GO:1903047,GO:1904813,GO:1990904	-	ko:K14293	ko03013,map03013	-	-	-	ko00000,ko00001,ko03009,ko03036	1.I.1	-	-	HEAT,HEAT_EZ,IBN_N
k59_523947_1	1485545.JQLW01000006_gene437	5.58e-58	193.0	COG0443@1|root,COG0443@2|Bacteria,1P7BK@1224|Proteobacteria	1224|Proteobacteria	O	PRTRC system protein D	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
k59_564469_2	335543.Sfum_1607	1.51e-20	84.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,42WTD@68525|delta/epsilon subdivisions,2WSRU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	atpZ	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
k59_486160_1	710111.FraQA3DRAFT_4543	2.14e-05	50.1	COG0454@1|root,COG0456@2|Bacteria,2IH3K@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
k59_486160_2	429009.Adeg_0325	1.4e-24	101.0	COG1082@1|root,COG1082@2|Bacteria,1V1Y1@1239|Firmicutes,24Y9G@186801|Clostridia,42HWD@68295|Thermoanaerobacterales	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_760074_1	439235.Dalk_4515	7.88e-91	283.0	COG3316@1|root,COG3316@2|Bacteria,1RHKZ@1224|Proteobacteria,43CRI@68525|delta/epsilon subdivisions,2X7Z7@28221|Deltaproteobacteria,2MIWI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
k59_998511_2	570967.JMLV01000009_gene1085	1.15e-30	117.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2JQKF@204441|Rhodospirillales	204441|Rhodospirillales	C	III protein, CoA-transferase family	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
k59_682023_1	309801.trd_1574	1.15e-48	166.0	COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi,27XZ5@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_798884_1	1121405.dsmv_0444	5.24e-77	237.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2WNPX@28221|Deltaproteobacteria,2MJIB@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_998528_1	926561.KB900617_gene1873	4.08e-50	177.0	COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia,3WB2B@53433|Halanaerobiales	186801|Clostridia	S	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_369020_1	243233.MCA3020	2.09e-93	299.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1XDY0@135618|Methylococcales	135618|Methylococcales	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_1113096_1	1407650.BAUB01000012_gene2077	2.1e-12	62.8	COG0184@1|root,COG0184@2|Bacteria,1G7NP@1117|Cyanobacteria,1H0T3@1129|Synechococcus	1117|Cyanobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
k59_1113096_2	187272.Mlg_1944	4.17e-38	141.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1WW27@135613|Chromatiales	135613|Chromatiales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_486192_1	1121405.dsmv_1992	6.65e-55	176.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SED@68525|delta/epsilon subdivisions,2WPP9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE-2	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
k59_410113_1	1279017.AQYJ01000028_gene2268	2.71e-86	281.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWTT@1224|Proteobacteria,1RP0H@1236|Gammaproteobacteria,46CKB@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_172566_1	1085623.GNIT_1972	2.29e-33	125.0	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,1SGXK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1191596_1	360095.BARBAKC583_1038	3.65e-05	45.4	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2TR10@28211|Alphaproteobacteria,48TE9@772|Bartonellaceae	28211|Alphaproteobacteria	C	Electron transfer flavoprotein domain	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k59_1191596_2	744979.R2A130_1848	1.08e-84	256.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2TR4J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
k59_998580_1	1121405.dsmv_2054	1.6e-40	148.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2MJR3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.3	ko:K07306	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_329301_1	748280.NH8B_3720	9e-13	66.2	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,2KRFH@206351|Neisseriales	206351|Neisseriales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
k59_329301_2	243233.MCA0982	1.25e-16	78.2	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1XFEK@135618|Methylococcales	135618|Methylococcales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_1233585_2	1216976.AX27061_4232	1.89e-29	117.0	COG2334@1|root,COG2334@2|Bacteria,1MXTW@1224|Proteobacteria,2VUCA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
k59_682106_1	96561.Dole_0800	9.06e-58	191.0	COG0636@1|root,COG0636@2|Bacteria,1MZ0M@1224|Proteobacteria,42T8K@68525|delta/epsilon subdivisions,2WPRA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_C
k59_369078_1	123899.JPQP01000021_gene3672	4.38e-05	51.2	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,3T2EM@506|Alcaligenaceae	28216|Betaproteobacteria	T	Histidine kinase	narX	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
k59_369078_2	1161401.ASJA01000020_gene580	3.85e-12	66.2	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria,43WVB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	K -dependent Na Ca	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
k59_1038018_1	754436.JCM19237_5134	1.05e-17	86.7	COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,1RRE3@1236|Gammaproteobacteria,1Y2PS@135623|Vibrionales	135623|Vibrionales	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_721636_1	1121405.dsmv_0075	5.3e-41	153.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,42MX2@68525|delta/epsilon subdivisions,2WIUV@28221|Deltaproteobacteria,2MJZI@213118|Desulfobacterales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_838714_1	398720.MED217_06117	1.21e-10	61.6	COG1416@1|root,COG1416@2|Bacteria,4NQQE@976|Bacteroidetes,1I35I@117743|Flavobacteriia,2XK6V@283735|Leeuwenhoekiella	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k59_838714_2	886377.Murru_3297	3.81e-31	121.0	COG4805@1|root,COG4805@2|Bacteria,4NK1Q@976|Bacteroidetes,1I13H@117743|Flavobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1073457_1	717772.THIAE_04785	2.05e-07	52.4	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,461JQ@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the 5'-nucleotidase family	-	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
k59_1073457_2	713586.KB900536_gene1067	3.76e-21	95.1	COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,1RYCQ@1236|Gammaproteobacteria,1WXWT@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
k59_525744_1	879212.DespoDRAFT_00279	2.72e-78	248.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,2MI1E@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k59_1191652_1	936455.KI421499_gene4503	3.47e-80	249.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TRB6@28211|Alphaproteobacteria,3JS4V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	MA20_17255	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
k59_251386_1	998674.ATTE01000001_gene3217	4.07e-66	210.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1S32J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	paaF	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
k59_721661_2	1150621.SMUL_3100	4.92e-11	62.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2YPF4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_998680_1	290397.Adeh_3845	1.79e-54	186.0	COG0312@1|root,COG0312@2|Bacteria,1RBJZ@1224|Proteobacteria,42YBE@68525|delta/epsilon subdivisions,2WUP7@28221|Deltaproteobacteria,2YZ4Y@29|Myxococcales	28221|Deltaproteobacteria	L	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_290686_1	713586.KB900536_gene3049	6.16e-61	213.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1WWAH@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, chain G	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
k59_956460_2	1129794.C427_3860	6.43e-26	104.0	COG1257@1|root,COG1257@2|Bacteria,1Q6M1@1224|Proteobacteria,1RPEP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	hydroxymethylglutaryl-CoA reductase	-	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
k59_486297_1	991.IW20_09670	8.77e-69	225.0	COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1HY0V@117743|Flavobacteriia,2NU4U@237|Flavobacterium	976|Bacteroidetes	I	Methylcrotonoyl-CoA carboxylase	accD5	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
k59_133362_1	1121374.KB891576_gene236	8.44e-30	125.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T1GZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_329387_1	933262.AXAM01000009_gene1485	4.08e-101	300.0	COG0727@1|root,COG0727@2|Bacteria,1Q0JM@1224|Proteobacteria,42N6S@68525|delta/epsilon subdivisions,2WMTR@28221|Deltaproteobacteria,2MIXY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
k59_956480_1	717785.HYPMC_3180	1.27e-54	185.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,3N89M@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	PQQ-like domain	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k59_369147_2	518766.Rmar_0949	8.92e-51	176.0	COG1763@1|root,COG1763@2|Bacteria,4PM6G@976|Bacteroidetes,1FK05@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Mo-molybdopterin cofactor biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_564646_1	485915.Dret_0226	2.82e-104	330.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,43BJY@68525|delta/epsilon subdivisions,2WIWD@28221|Deltaproteobacteria,2M9AS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Formate dehydrogenase, alpha subunit	fdnG-2	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_212082_1	589865.DaAHT2_1374	3.56e-40	147.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria,2MI77@213118|Desulfobacterales	28221|Deltaproteobacteria	S	permease YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_447065_1	264198.Reut_C6071	6.74e-58	194.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2VIE4@28216|Betaproteobacteria,1K2M0@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1_6,DUF772
k59_172714_1	998674.ATTE01000001_gene1575	2.35e-149	431.0	COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1MXER@1224|Proteobacteria,1RRTA@1236|Gammaproteobacteria,463TH@72273|Thiotrichales	72273|Thiotrichales	CF	Dihydroorotate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DHO_dh,Fer4_21
k59_369196_1	631362.Thi970DRAFT_03095	4.97e-16	78.2	28T0P@1|root,2ZF9Z@2|Bacteria,1RAUV@1224|Proteobacteria,1S23D@1236|Gammaproteobacteria,1WY26@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_682230_1	1122207.MUS1_10960	4.11e-58	185.0	COG4635@1|root,COG4635@2|Bacteria,1RAH2@1224|Proteobacteria,1S372@1236|Gammaproteobacteria,1XPRR@135619|Oceanospirillales	135619|Oceanospirillales	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
k59_682230_2	243231.GSU2486	6.44e-06	47.0	COG2403@1|root,COG2403@2|Bacteria,1MV4C@1224|Proteobacteria,42NE0@68525|delta/epsilon subdivisions,2WJ94@28221|Deltaproteobacteria,43TJC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_998782_1	981384.AEYW01000001_gene1490	2.88e-81	254.0	COG1234@1|root,COG1234@2|Bacteria,1RIJP@1224|Proteobacteria	1224|Proteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_4
k59_564688_1	1049564.TevJSym_aw00050	2.1e-50	165.0	2BW2S@1|root,32QYV@2|Bacteria,1RI5M@1224|Proteobacteria,1S614@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_54808_1	909663.KI867150_gene2735	3.86e-99	303.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MRAR@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_1113282_1	880072.Desac_2147	1.44e-122	379.0	COG0458@1|root,COG0458@2|Bacteria,1NPMZ@1224|Proteobacteria,42NF3@68525|delta/epsilon subdivisions,2WM4C@28221|Deltaproteobacteria,2MQ8X@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase large chain, oligomerisation	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0661	CPSase_L_D2,CPSase_L_D3,MGS
k59_1113293_1	1033802.SSPSH_002066	1.75e-76	242.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
k59_251496_1	406817.XNC1_0674	2.9e-08	55.1	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,1RMK8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Branched-chain amino acid transport	livF	GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008144,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:0098655,GO:0098656,GO:1901265,GO:1901363,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	iAPECO1_1312.APECO1_3005,iECs_1301.ECs4301,iSSON_1240.SSON_3692,iUTI89_1310.UTI89_C3961,iYL1228.KPN_03816,iZ_1308.Z4824	ABC_tran,BCA_ABC_TP_C
k59_251496_2	387631.Asulf_01860	1.69e-65	207.0	COG0411@1|root,arCOG00926@2157|Archaea,2XU0T@28890|Euryarchaeota,245P6@183980|Archaeoglobi	183980|Archaeoglobi	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_212145_1	883.DvMF_1967	1.21e-27	114.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2M9BW@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1038221_1	631362.Thi970DRAFT_00922	1.31e-42	151.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1WVUM@135613|Chromatiales	135613|Chromatiales	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1038221_2	768671.ThimaDRAFT_4194	1.61e-48	164.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1WWIU@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_604328_1	1477404.A0A023NGI5_9CAUD	6.65e-18	80.1	4QDMG@10239|Viruses,4QXNE@35237|dsDNA viruses  no RNA stage,4QQ5T@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_410414_1	880073.Calab_2785	6.35e-78	251.0	COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria	2|Bacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_1233849_1	1134912.AJTV01000013_gene609	1.43e-24	106.0	COG5361@1|root,COG5361@2|Bacteria,1MWTW@1224|Proteobacteria,2TUR1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_916683_1	237368.SCABRO_02030	5.23e-35	129.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
k59_329499_1	911045.PSE_3737	4.7e-45	164.0	COG1289@1|root,COG1289@2|Bacteria	2|Bacteria	S	transmembrane transporter activity	VPA1578	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_1073616_1	1265503.KB905161_gene3128	4.76e-35	137.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,2Q6QB@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	ynaI	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_1073618_1	177437.HRM2_39300	4.59e-61	209.0	COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria,42TR8@68525|delta/epsilon subdivisions,2WQC1@28221|Deltaproteobacteria,2MMMU@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
k59_1152283_1	9606.ENSP00000247461	1.89e-168	489.0	KOG0675@1|root,KOG0675@2759|Eukaryota,38HTR@33154|Opisthokonta,3BAHV@33208|Metazoa,3CSIV@33213|Bilateria,482UX@7711|Chordata,48ZNA@7742|Vertebrata,3J96F@40674|Mammalia,35M0D@314146|Euarchontoglires,4M76Q@9443|Primates,4MVV5@9604|Hominidae	33208|Metazoa	U	Calreticulin family	CANX	GO:0000003,GO:0001894,GO:0001895,GO:0002376,GO:0002474,GO:0002478,GO:0002495,GO:0002504,GO:0002790,GO:0003674,GO:0005102,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005789,GO:0005790,GO:0005840,GO:0005886,GO:0006457,GO:0006726,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0006950,GO:0006986,GO:0007154,GO:0007165,GO:0007166,GO:0007338,GO:0007568,GO:0008104,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009306,GO:0009408,GO:0009566,GO:0009628,GO:0009987,GO:0010033,GO:0010522,GO:0010959,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016063,GO:0016192,GO:0019221,GO:0019538,GO:0019882,GO:0019884,GO:0019886,GO:0019953,GO:0022414,GO:0023052,GO:0030176,GO:0030424,GO:0030425,GO:0030968,GO:0031224,GO:0031227,GO:0031647,GO:0031974,GO:0031984,GO:0032501,GO:0032502,GO:0032838,GO:0032839,GO:0032879,GO:0032940,GO:0032991,GO:0033036,GO:0033554,GO:0034097,GO:0034185,GO:0034620,GO:0034975,GO:0034976,GO:0035254,GO:0035255,GO:0035966,GO:0035967,GO:0036465,GO:0036477,GO:0042175,GO:0042221,GO:0042440,GO:0042441,GO:0042592,GO:0042886,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043169,GO:0043170,GO:0043197,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043269,GO:0043324,GO:0043473,GO:0043474,GO:0044232,GO:0044233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044297,GO:0044309,GO:0044322,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0044703,GO:0045184,GO:0045202,GO:0046148,GO:0046154,GO:0046872,GO:0046903,GO:0048002,GO:0048066,GO:0048069,GO:0048471,GO:0048488,GO:0048871,GO:0050789,GO:0050794,GO:0050821,GO:0050896,GO:0051049,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0051924,GO:0060249,GO:0060341,GO:0061077,GO:0065007,GO:0065008,GO:0070013,GO:0070106,GO:0070757,GO:0070887,GO:0071310,GO:0071345,GO:0071556,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072583,GO:0097038,GO:0097447,GO:0097458,GO:0098552,GO:0098553,GO:0098657,GO:0098794,GO:0098827,GO:0099003,GO:0099504,GO:0099568,GO:0120025,GO:0120038,GO:0120111,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K08054,ko:K09551	ko04141,ko04145,ko04612,ko04918,ko05166,map04141,map04145,map04612,map04918,map05166	-	-	-	ko00000,ko00001,ko03110,ko04091,ko04131	-	-	-	Calreticulin
k59_525917_1	1122609.AUGT01000013_gene4134	2.22e-33	122.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria,4DRZ2@85009|Propionibacteriales	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k59_799127_1	335543.Sfum_1724	1.8e-172	495.0	COG0069@1|root,COG1145@1|root,COG0069@2|Bacteria,COG1145@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJ17@28221|Deltaproteobacteria,2MRAB@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S double cluster binding domain	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_16,Glu_synthase
k59_95449_1	9694.XP_007073490.1	1.03e-198	556.0	COG0256@1|root,KOG0875@2759|Eukaryota,38BT6@33154|Opisthokonta,3BDDH@33208|Metazoa,3CXDW@33213|Bilateria,484F8@7711|Chordata,49085@7742|Vertebrata,3J50V@40674|Mammalia,3EH5K@33554|Carnivora	33208|Metazoa	J	ribosomal protein	RPL5	GO:0000027,GO:0000184,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005783,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006417,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0008097,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0010035,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010921,GO:0010922,GO:0012505,GO:0015031,GO:0015833,GO:0015934,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0017101,GO:0019220,GO:0019222,GO:0019439,GO:0019538,GO:0019843,GO:0019899,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0023051,GO:0030162,GO:0030234,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031625,GO:0031647,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0033036,GO:0033365,GO:0034248,GO:0034250,GO:0034470,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0035303,GO:0035306,GO:0042176,GO:0042177,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0042886,GO:0043043,GO:0043085,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044389,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0045727,GO:0045861,GO:0045937,GO:0046483,GO:0046700,GO:0046907,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051336,GO:0051338,GO:0051340,GO:0051345,GO:0051348,GO:0051351,GO:0051438,GO:0051444,GO:0051641,GO:0051649,GO:0051716,GO:0055105,GO:0055106,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070727,GO:0070887,GO:0070925,GO:0070972,GO:0071241,GO:0071702,GO:0071704,GO:0071705,GO:0071826,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0080090,GO:0090150,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901796,GO:1902531,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903630,GO:1903632,GO:1904666,GO:1904667,GO:1905015,GO:1905017,GO:1905018,GO:1905020,GO:1905021,GO:1905023,GO:1990904,GO:1990948,GO:2000058,GO:2000059,GO:2000112,GO:2000434,GO:2000435	-	ko:K02932	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko01009,ko03011	-	-	-	Ribosomal_L18_c,Ribosomal_L5e
k59_133511_1	745718.JADT01000007_gene2776	1.45e-07	57.4	COG3934@1|root,COG3934@2|Bacteria,4NHVX@976|Bacteroidetes,1HY3I@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
k59_760373_1	1185876.BN8_00738	1.11e-55	184.0	COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,47KEY@768503|Cytophagia	976|Bacteroidetes	S	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
k59_1191232_1	335543.Sfum_3459	9.08e-54	180.0	COG1309@1|root,COG1309@2|Bacteria,1Q299@1224|Proteobacteria,42UP4@68525|delta/epsilon subdivisions,2WQF0@28221|Deltaproteobacteria,2MS2K@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_15419_1	1254432.SCE1572_04480	4.62e-29	120.0	COG1716@1|root,COG2203@1|root,COG3829@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YI@28221|Deltaproteobacteria,2YZGR@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
k59_525339_1	237368.SCABRO_02856	2.25e-32	129.0	28NDD@1|root,2ZBG6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_798603_1	1385935.N836_33920	4.58e-51	183.0	COG2905@1|root,COG5001@1|root,COG2905@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,1H9V4@1150|Oscillatoriales	1117|Cyanobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_4,PAS_9
k59_368686_1	1232410.KI421425_gene1553	1.41e-48	172.0	COG4932@1|root,COG4932@2|Bacteria,1QZFW@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_956016_1	314282.PCNPT3_10615	1.79e-25	109.0	COG3528@1|root,COG3528@2|Bacteria,1R601@1224|Proteobacteria,1SWW1@1236|Gammaproteobacteria,2QJ6B@267894|Psychromonadaceae	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
k59_603767_1	1232683.ADIMK_0084	5.71e-45	162.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,464A6@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_15443_1	29581.BW37_04056	7.38e-130	382.0	COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,2W0HG@28216|Betaproteobacteria,4727U@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4478)	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DUF3412,DUF4478,Lysine_decarbox
k59_409685_1	314285.KT71_11064	1.88e-108	325.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1J7ES@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	MFS/sugar transport protein	ynaJ	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
k59_956041_1	235279.HH_1270	2.09e-25	115.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2YMA1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
k59_172257_1	338963.Pcar_2454	4.87e-37	133.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,43UXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
k59_1191297_1	1379698.RBG1_1C00001G1206	1.19e-65	215.0	COG1215@1|root,COG1215@2|Bacteria,2NQN7@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
k59_368734_1	177437.HRM2_41800	2.39e-65	214.0	2DBU2@1|root,2ZB3S@2|Bacteria,1N1MT@1224|Proteobacteria,42VJX@68525|delta/epsilon subdivisions,2WSPP@28221|Deltaproteobacteria,2MNKM@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_681757_1	596151.DesfrDRAFT_3125	1.08e-106	320.0	COG4671@1|root,COG4671@2|Bacteria,1N1PQ@1224|Proteobacteria,42MDW@68525|delta/epsilon subdivisions,2WKQK@28221|Deltaproteobacteria,2M92X@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Glycosyltransferase 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k59_877565_1	1298593.TOL_1702	1.27e-26	111.0	COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,1XHHM@135619|Oceanospirillales	135619|Oceanospirillales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
k59_998171_1	1121013.P873_12090	3.67e-75	243.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1X8AF@135614|Xanthomonadales	135614|Xanthomonadales	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_525396_2	395961.Cyan7425_3862	1.18e-08	55.8	COG2010@1|root,COG2010@2|Bacteria,1G7QR@1117|Cyanobacteria,3KIGW@43988|Cyanothece	1117|Cyanobacteria	C	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis	petJ	-	-	ko:K08906	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Cytochrome_CBB3
k59_409760_1	1280949.HAD_14887	2.84e-16	71.6	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,43YF2@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_1151799_1	138119.DSY4729	1.39e-64	218.0	COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia,260K6@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
k59_1151811_1	331869.BAL199_15663	3.23e-69	224.0	COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,2TU4M@28211|Alphaproteobacteria,4BPY8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator superfamily	ycaD	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_446647_1	396588.Tgr7_0028	2.74e-36	134.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,1RM9K@1236|Gammaproteobacteria,1WWAM@135613|Chromatiales	135613|Chromatiales	H	Uroporphyrinogen III synthase	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
k59_1112838_1	998088.B565_3239	4.28e-30	112.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1Y4EP@135624|Aeromonadales	135624|Aeromonadales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
k59_1112838_2	1124983.PFLCHA0_c06830	2.46e-37	131.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1YPGV@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0560	DHquinase_II
k59_54388_1	870187.Thini_0278	5.64e-67	218.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,4637B@72273|Thiotrichales	72273|Thiotrichales	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_409824_1	1042375.AFPL01000013_gene2447	1.61e-119	357.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RMQB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tripartite tricarboxylate transporter TctA	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
k59_916259_1	414684.RC1_3768	2.15e-79	243.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,2U5PV@28211|Alphaproteobacteria,2JU2N@204441|Rhodospirillales	204441|Rhodospirillales	M	Cytidylyltransferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
k59_172334_1	596154.Alide2_1838	5.65e-92	280.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2VMWG@28216|Betaproteobacteria,4AGCJ@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
k59_1037667_1	439292.Bsel_1392	1.12e-23	105.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,26PB5@186821|Sporolactobacillaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	lcfA	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_446683_1	1123368.AUIS01000014_gene2313	2.01e-06	56.2	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,2NC64@225057|Acidithiobacillales	225057|Acidithiobacillales	S	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
k59_251094_1	349521.HCH_02237	1.51e-67	216.0	COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,1T1TQ@1236|Gammaproteobacteria,1XHUZ@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs	cmoB	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_9
k59_409850_2	388051.AUFE01000004_gene894	8.35e-90	270.0	COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria,2W9V7@28216|Betaproteobacteria,1K54Q@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_95004_1	96561.Dole_1556	7.62e-96	296.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WIJ5@28221|Deltaproteobacteria,2MHSR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_916288_1	9361.ENSDNOP00000011420	3.18e-149	436.0	COG0459@1|root,KOG0358@2759|Eukaryota,39NW1@33154|Opisthokonta,3BCK9@33208|Metazoa,3CVW1@33213|Bilateria,47ZFR@7711|Chordata,4981V@7742|Vertebrata,3J3H0@40674|Mammalia	33208|Metazoa	O	positive regulation of telomerase RNA localization to Cajal body	CCT4	GO:0000003,GO:0002199,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005832,GO:0005856,GO:0005874,GO:0006403,GO:0006457,GO:0006458,GO:0006810,GO:0007275,GO:0007338,GO:0007339,GO:0008037,GO:0008150,GO:0009566,GO:0009653,GO:0009791,GO:0009886,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009988,GO:0010171,GO:0010556,GO:0010557,GO:0010604,GO:0010638,GO:0015630,GO:0019219,GO:0019222,GO:0019953,GO:0022414,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031647,GO:0031974,GO:0031981,GO:0032204,GO:0032206,GO:0032210,GO:0032212,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0035036,GO:0040032,GO:0043085,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044093,GO:0044183,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044703,GO:0045935,GO:0048518,GO:0048522,GO:0048856,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0051052,GO:0051054,GO:0051082,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051338,GO:0051347,GO:0051704,GO:0051972,GO:0051973,GO:0060255,GO:0060341,GO:0061077,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070202,GO:0070203,GO:0080090,GO:0090666,GO:0090670,GO:0090685,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0101031,GO:1901998,GO:1903827,GO:1903829,GO:1904356,GO:1904358,GO:1904814,GO:1904816,GO:1904851,GO:1904872,GO:1904874,GO:1904951,GO:2000112,GO:2000278,GO:2000573,GO:2001252	-	ko:K09496	-	-	-	-	ko00000,ko03036,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_15577_1	945550.VISI1226_16783	3.63e-41	150.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1XTJM@135623|Vibrionales	135623|Vibrionales	M	3-deoxy-D-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
k59_564348_1	1123258.AQXZ01000006_gene163	1.13e-73	243.0	COG1505@1|root,COG1505@2|Bacteria,2IRXB@201174|Actinobacteria,4FWTT@85025|Nocardiaceae	201174|Actinobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
k59_759955_1	177437.HRM2_26760	2.91e-68	233.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,2MI31@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iAF987.Gmet_2474	OstA,OstA_2,OstA_C
k59_290402_1	933262.AXAM01000001_gene333	2.9e-24	102.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2MHP7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_251135_1	1550091.JROE01000004_gene1467	4.52e-12	71.6	COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IX4V@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_1112933_1	9707.XP_004407670.1	6.29e-21	93.2	COG1972@1|root,KOG3747@2759|Eukaryota,38CC4@33154|Opisthokonta,3BEAF@33208|Metazoa,3CZWK@33213|Bilateria,483X3@7711|Chordata,492UH@7742|Vertebrata,3JDYN@40674|Mammalia,3EGFB@33554|Carnivora	33208|Metazoa	FP	Solute carrier family 28	SLC28A3	GO:0001894,GO:0001895,GO:0003674,GO:0005215,GO:0005337,GO:0005345,GO:0005350,GO:0005415,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006863,GO:0008150,GO:0008324,GO:0012505,GO:0015075,GO:0015077,GO:0015081,GO:0015205,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015389,GO:0015390,GO:0015391,GO:0015672,GO:0015851,GO:0015855,GO:0015858,GO:0015860,GO:0015864,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0031984,GO:0032501,GO:0034220,GO:0035725,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0046873,GO:0048871,GO:0051179,GO:0051234,GO:0055085,GO:0060249,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0072531,GO:0098655,GO:0098660,GO:0098662,GO:0098827,GO:1901264,GO:1901505,GO:1901642,GO:1904823	-	ko:K11536	-	-	-	-	ko00000,ko02000	2.A.41.2	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
k59_486047_1	765913.ThidrDRAFT_2034	1.34e-84	250.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria,1WY2D@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM sulfur relay protein TusD DsrE	dsrE	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0019417,GO:0044237,GO:0055114	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
k59_486047_2	1049564.TevJSym_aw00170	1.4e-20	84.3	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,1SD0S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the DsrF TusC family	tusC	GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
k59_486054_1	1265505.ATUG01000002_gene1029	7.23e-72	233.0	COG0438@1|root,COG0438@2|Bacteria,1R7ZD@1224|Proteobacteria,42PZN@68525|delta/epsilon subdivisions,2WKSY@28221|Deltaproteobacteria,2MIJW@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_133125_1	926569.ANT_09880	6.82e-28	112.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi	2|Bacteria	J	PFAM RNA binding S1 domain protein	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
k59_409931_1	768671.ThimaDRAFT_3217	2.32e-103	310.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1WWG6@135613|Chromatiales	135613|Chromatiales	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_838514_1	933262.AXAM01000013_gene1298	6.39e-41	144.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2MJVB@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
k59_798786_2	1267005.KB911266_gene1250	1.27e-178	506.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,3N7U4@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_798786_3	420324.KI912027_gene316	5.86e-35	129.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,1JX9I@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_603972_1	1125863.JAFN01000001_gene166	1.95e-31	122.0	COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,42ND9@68525|delta/epsilon subdivisions,2WK5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_681924_1	1458275.AZ34_07525	1.93e-79	244.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2VIZ9@28216|Betaproteobacteria,4AARP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
k59_133140_1	690850.Desaf_1234	6.9e-103	315.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M915@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_916353_1	1189620.AJXL01000002_gene1838	1.82e-73	230.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1HXRP@117743|Flavobacteriia,2NUGR@237|Flavobacterium	976|Bacteroidetes	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
k59_1191476_1	298386.PBPRA1633	4.95e-19	80.9	COG0073@1|root,COG0073@2|Bacteria,1QRBG@1224|Proteobacteria,1SNZX@1236|Gammaproteobacteria,1XXC4@135623|Vibrionales	135623|Vibrionales	J	Putative tRNA binding domain	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
k59_1191476_2	1304875.JAFZ01000003_gene543	1.4e-55	184.0	COG1915@1|root,COG1915@2|Bacteria,3TAQR@508458|Synergistetes	508458|Synergistetes	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1191480_1	1294273.roselon_02372	6.86e-72	237.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1MWD4@1224|Proteobacteria,2TUPI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CI	phenylacetic acid degradation protein	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,MaoC_dehydratas
k59_329159_1	754477.Q7C_1626	7.23e-16	80.9	COG2885@1|root,COG2885@2|Bacteria,1RGHU@1224|Proteobacteria,1S5H8@1236|Gammaproteobacteria,463ME@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3
k59_525572_1	270374.MELB17_21525	8.96e-107	339.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,1RSEQ@1236|Gammaproteobacteria,465RF@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
k59_54531_1	1232666.JANE01000027_gene1432	2.48e-08	58.2	COG1802@1|root,COG1802@2|Bacteria,1TSJY@1239|Firmicutes,4HBY3@91061|Bacilli,4GY6G@90964|Staphylococcaceae	91061|Bacilli	K	Gluconate operon transcriptional repressor	gntR	-	-	ko:K11476	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
k59_604013_1	1121405.dsmv_3391	7.63e-72	236.0	COG0493@1|root,COG2878@1|root,COG0493@2|Bacteria,COG2878@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2WIVF@28221|Deltaproteobacteria,2MIVJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Fe-S cluster domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fer4,Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
k59_446849_1	1177154.Y5S_01067	1.11e-49	174.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,1XH9D@135619|Oceanospirillales	135619|Oceanospirillales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_525596_1	30611.ENSOGAP00000003418	3.69e-196	547.0	COG0244@1|root,KOG0815@2759|Eukaryota,38BU8@33154|Opisthokonta,3BAZV@33208|Metazoa,3CZPS@33213|Bilateria,4860P@7711|Chordata,48VIY@7742|Vertebrata,3JAAE@40674|Mammalia,35HFK@314146|Euarchontoglires,4MBFC@9443|Primates	33208|Metazoa	J	Ribosomal protein L10	RPLP0	GO:0000184,GO:0000956,GO:0002181,GO:0003674,GO:0003735,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007589,GO:0007595,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009719,GO:0009790,GO:0009792,GO:0009892,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010269,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0012505,GO:0014070,GO:0014074,GO:0015031,GO:0015833,GO:0015934,GO:0016020,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019221,GO:0019222,GO:0019439,GO:0019538,GO:0022625,GO:0022626,GO:0023052,GO:0030425,GO:0030879,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0033993,GO:0034097,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0035690,GO:0035722,GO:0035770,GO:0036464,GO:0036477,GO:0042221,GO:0042277,GO:0042493,GO:0042886,GO:0042995,GO:0043005,GO:0043009,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044463,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046683,GO:0046700,GO:0046903,GO:0046907,GO:0048513,GO:0048519,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0050794,GO:0050878,GO:0050896,GO:0051179,GO:0051234,GO:0051591,GO:0051641,GO:0051649,GO:0051716,GO:0052720,GO:0060255,GO:0065007,GO:0065008,GO:0070670,GO:0070671,GO:0070727,GO:0070887,GO:0070972,GO:0071310,GO:0071320,GO:0071345,GO:0071349,GO:0071353,GO:0071396,GO:0071407,GO:0071417,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0090305,GO:0097305,GO:0097306,GO:0097327,GO:0097447,GO:0097458,GO:0120025,GO:0120038,GO:0140097,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1904400,GO:1904401,GO:1904587,GO:1904588,GO:1904627,GO:1904628,GO:1990904	-	ko:K02941	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s,Ribosomal_L10
k59_1191514_2	1122993.KB898327_gene723	3.69e-32	124.0	COG1397@1|root,COG5579@1|root,COG1397@2|Bacteria,COG5579@2|Bacteria,4NTDS@976|Bacteroidetes,2G0U6@200643|Bacteroidia	976|Bacteroidetes	O	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH,DUF1810
k59_998467_1	927658.AJUM01000037_gene1892	1.08e-32	127.0	COG0577@1|root,COG0577@2|Bacteria,4NFUG@976|Bacteroidetes,2FM5B@200643|Bacteroidia,3XJN1@558415|Marinilabiliaceae	976|Bacteroidetes	V	MacB-like periplasmic core domain	macB_3	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_721523_1	243231.GSU0070	1.25e-83	260.0	COG4881@1|root,COG4881@2|Bacteria,1QXMX@1224|Proteobacteria,43C41@68525|delta/epsilon subdivisions,2WKYD@28221|Deltaproteobacteria,43TBN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Polysulphide reductase, NrfD	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
k59_956301_1	1101195.Meth11DRAFT_1307	2.14e-64	204.0	COG3040@1|root,COG3040@2|Bacteria,1RIKA@1224|Proteobacteria,2VTSY@28216|Betaproteobacteria,2KMTG@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
k59_564469_1	635013.TherJR_1142	5.28e-20	89.4	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,26072@186807|Peptococcaceae	186801|Clostridia	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_919235_1	1121441.AUCX01000021_gene697	4.72e-17	79.7	COG0069@1|root,COG1145@1|root,COG0069@2|Bacteria,COG1145@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJ17@28221|Deltaproteobacteria,2M82G@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the glutamate synthase family	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_16,Glu_synthase
k59_919235_2	1121405.dsmv_2721	2.54e-83	256.0	COG0067@1|root,COG0067@2|Bacteria,1MW6C@1224|Proteobacteria,42MTE@68525|delta/epsilon subdivisions,2WJ9E@28221|Deltaproteobacteria,2MI1S@213118|Desulfobacterales	28221|Deltaproteobacteria	E	glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_801653_1	926550.CLDAP_24510	1.34e-43	163.0	COG2273@1|root,COG2273@2|Bacteria,2G7RY@200795|Chloroflexi	200795|Chloroflexi	G	Glycoside hydrolase family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_1194546_1	426114.THI_0146	6.3e-32	113.0	COG2154@1|root,COG2154@2|Bacteria,1NKCS@1224|Proteobacteria,2VYEM@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Pterin 4 alpha carbinolamine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Pterin_4a
k59_1194546_2	1313172.YM304_20260	1.4e-06	51.6	COG1192@1|root,COG1192@2|Bacteria,2H4UC@201174|Actinobacteria	201174|Actinobacteria	D	chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_136078_1	717231.Flexsi_0440	3.25e-57	191.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1155007_1	95619.PM1_0225735	5.41e-65	211.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	4-amino-4-deoxychorismate lyase	pabC	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_177,iE2348C_1286.E2348C_1188,iECED1_1282.ECED1_1239,iECNA114_1301.ECNA114_1153,iECOK1_1307.ECOK1_1203,iECS88_1305.ECS88_1110,iECSF_1327.ECSF_0995,iECUMN_1333.ECUMN_1273,iJN746.PP_1917,iPC815.YPO1603,iUMN146_1321.UM146_11845,iUTI89_1310.UTI89_C1222,ic_1306.c1366	Aminotran_4
k59_332207_1	194439.CT0862	1.23e-55	187.0	COG2046@1|root,COG2046@2|Bacteria,1FF05@1090|Chlorobi	1090|Chlorobi	F	sulfate assimilation	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
k59_763077_1	1121937.AUHJ01000006_gene2548	0.000414	43.1	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,464EI@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0025,iJN746.PP_0602	FAD_syn,Flavokinase
k59_763077_2	2340.JV46_14590	2.75e-53	186.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1J4ES@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_1155039_1	1265505.ATUG01000002_gene1466	1.65e-42	153.0	2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,42R2G@68525|delta/epsilon subdivisions,2WMQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_372027_2	1041139.KB902683_gene2761	1.32e-41	154.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_176364_2	470145.BACCOP_00980	1.63e-12	65.5	COG4461@1|root,COG4461@2|Bacteria,4NIBZ@976|Bacteroidetes,2FXTJ@200643|Bacteroidia,4ATXC@815|Bacteroidaceae	976|Bacteroidetes	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PliI
k59_841657_1	203122.Sde_0988	9.54e-121	370.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,464CN@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.41,3.2.1.68	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k59_73543_1	483219.LILAB_15970	1.04e-39	145.0	COG1232@1|root,COG1232@2|Bacteria,1R7EY@1224|Proteobacteria	1224|Proteobacteria	H	amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
k59_233955_1	335543.Sfum_3911	3.8e-60	207.0	COG0458@1|root,COG0458@2|Bacteria,1NPMZ@1224|Proteobacteria,42NF3@68525|delta/epsilon subdivisions,2WM4C@28221|Deltaproteobacteria,2MQ8X@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase large chain, oligomerisation	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0661	CPSase_L_D2,CPSase_L_D3,MGS
k59_548474_1	886293.Sinac_5758	1.17e-57	189.0	COG1082@1|root,COG1082@2|Bacteria,2IXXS@203682|Planctomycetes	203682|Planctomycetes	G	PFAM AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
k59_623715_1	1089553.Tph_c10330	4.2e-22	97.8	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia,42FMI@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
k59_310099_1	1121035.AUCH01000016_gene2216	1.93e-46	169.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,2KV1V@206389|Rhodocyclales	206389|Rhodocyclales	P	cation transport ATPase	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_1132535_1	335283.Neut_0806	5.47e-29	116.0	28IUD@1|root,2Z8T4@2|Bacteria,1QZHS@1224|Proteobacteria,2VK06@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Carboxysome shell peptide mid-region	-	-	-	-	-	-	-	-	-	-	-	-	CsoS2_M
k59_1132535_2	426114.THI_0138	3.42e-16	78.2	28K6U@1|root,2Z9V7@2|Bacteria,1MYVN@1224|Proteobacteria,2VNQ9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Carboxysome Shell Carbonic Anhydrase	-	-	-	-	-	-	-	-	-	-	-	-	CsoSCA
k59_349363_1	243233.MCA2477	6.33e-62	212.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1XE8M@135618|Methylococcales	135618|Methylococcales	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	DsbC,Thioredox_DsbH
k59_857882_1	61622.XP_010386983.1	9.11e-116	358.0	KOG1076@1|root,KOG1076@2759|Eukaryota,38EZF@33154|Opisthokonta,3BBRU@33208|Metazoa,3CRH9@33213|Bilateria,4845X@7711|Chordata,48YVK@7742|Vertebrata,3J5TD@40674|Mammalia,35KZ6@314146|Euarchontoglires,4MH0U@9443|Primates,362E6@314294|Cercopithecoidea	33208|Metazoa	J	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2 GTP methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression	EIF3C	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005852,GO:0006412,GO:0006413,GO:0006417,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031369,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065009,GO:0071541,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902415,GO:1902416,GO:1905214,GO:1905216,GO:2000112	-	ko:K03252	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	PCI,eIF-3c_N
k59_505689_1	1205680.CAKO01000008_gene4082	3.45e-73	236.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria,2JQ5F@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_623748_1	439235.Dalk_3749	6.18e-27	107.0	COG0716@1|root,COG1146@1|root,COG0716@2|Bacteria,COG1146@2|Bacteria,1NFA5@1224|Proteobacteria,42WN8@68525|delta/epsilon subdivisions	2|Bacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	fldA	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
k59_310124_1	1163408.UU9_03932	1.79e-72	232.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K12980	-	-	-	-	ko00000,ko01005	-	-	-	OMP_b-brl,Surface_Ag_2
k59_271358_1	316067.Geob_2386	2.66e-59	204.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,43RZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	elongation factor Tu domain 2 protein	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_505692_1	946077.W5A_04828	1.79e-59	206.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia	976|Bacteroidetes	G	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_116174_1	1123059.KB823013_gene607	5.88e-80	259.0	COG2176@1|root,COG2176@2|Bacteria,1QUVW@1224|Proteobacteria,2TSZS@28211|Alphaproteobacteria,43ZJG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	VRR_NUC	polC	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T,VRR_NUC
k59_548536_1	1163408.UU9_01384	5.7e-39	148.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RPRP@1236|Gammaproteobacteria,1X56U@135614|Xanthomonadales	135614|Xanthomonadales	S	Penicillin acylase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
k59_1092440_1	429009.Adeg_0997	2.59e-35	132.0	2BTHK@1|root,32NQ1@2|Bacteria,1VNHU@1239|Firmicutes,24W5Q@186801|Clostridia,42I9P@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_584248_1	42256.RradSPS_0729	2.71e-48	175.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4CPS6@84995|Rubrobacteria	84995|Rubrobacteria	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_191118_1	1232437.KL661965_gene3270	3.37e-105	322.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria,2MJNF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_73661_1	948565.AFFP02000027_gene168	8.98e-102	318.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1Y7TQ@135625|Pasteurellales	135625|Pasteurellales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_466118_1	648757.Rvan_1166	1.12e-42	144.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2TV7J@28211|Alphaproteobacteria,3N6R6@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
k59_466118_2	936455.KI421499_gene6933	2.52e-58	187.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2TSN3@28211|Alphaproteobacteria,3JS3B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
k59_35073_1	589865.DaAHT2_0568	5.64e-11	67.8	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2WIRS@28221|Deltaproteobacteria,2MJ0J@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Amidohydrolase family	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_740547_1	266779.Meso_1527	3.05e-62	204.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2TQMP@28211|Alphaproteobacteria,43HDK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	synthase	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
k59_116244_1	522306.CAP2UW1_2035	4.42e-14	71.6	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJ5E@28216|Betaproteobacteria,1KQBH@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	AMP-binding enzyme	bclA_2	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_116244_2	335541.Swol_1832	2.28e-14	71.6	COG1142@1|root,COG1142@2|Bacteria,1V3XG@1239|Firmicutes,24HK0@186801|Clostridia	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin	-	-	-	ko:K05796	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS08480	Fer4,Fer4_4,Fer4_7,Fer4_9
k59_271441_1	172088.AUGA01000004_gene3962	3.86e-99	305.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,3JRNE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
k59_1092485_1	536019.Mesop_3756	9.99e-17	80.1	2A1VG@1|root,30Q4R@2|Bacteria,1PA9D@1224|Proteobacteria,2UX6E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_349444_2	1094980.Mpsy_0544	3.68e-18	83.6	COG0677@1|root,arCOG00252@2157|Archaea,2Y2DT@28890|Euryarchaeota,2NAMQ@224756|Methanomicrobia	224756|Methanomicrobia	M	UDP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C
k59_1092492_2	1002339.HMPREF9373_2228	1.14e-72	232.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria,3NJ8Y@468|Moraxellaceae	1236|Gammaproteobacteria	C	Ubiquinol Oxidase	cioA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iJN746.PP_4651	Cyt_bd_oxida_I
k59_584323_1	717785.HYPMC_2408	1.62e-54	177.0	COG0583@1|root,COG0583@2|Bacteria,1MXC9@1224|Proteobacteria,2TTTY@28211|Alphaproteobacteria,3N7GR@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_584323_2	113395.AXAI01000009_gene2564	1.04e-18	80.9	COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,2U9A2@28211|Alphaproteobacteria,3JY1C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Fe-S metabolism associated domain	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
k59_35126_1	543526.Htur_1030	2.39e-36	139.0	COG0277@1|root,arCOG00340@2157|Archaea,2Y85H@28890|Euryarchaeota,24157@183963|Halobacteria	183963|Halobacteria	C	COG0277 FAD FMN-containing dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
k59_935608_1	1121396.KB892917_gene99	3.37e-16	74.7	COG2510@1|root,COG2510@2|Bacteria	2|Bacteria	EG	membrane	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
k59_505825_1	384765.SIAM614_19134	9.97e-22	93.6	COG4461@1|root,COG4461@2|Bacteria,1R6Q3@1224|Proteobacteria,2U74M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Membrane-bound lysozyme-inhibitor of c-type lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	LprI,MliC
k59_349479_1	1121405.dsmv_2792	2.58e-57	185.0	COG1102@1|root,COG1102@2|Bacteria,1N69V@1224|Proteobacteria,42UCK@68525|delta/epsilon subdivisions,2WQ7M@28221|Deltaproteobacteria,2MKKM@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
k59_271469_1	933262.AXAM01000023_gene662	1.98e-102	315.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2MI6Q@213118|Desulfobacterales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_191206_1	1122247.C731_4959	5.85e-18	83.6	COG1522@1|root,COG1522@2|Bacteria,2HSQU@201174|Actinobacteria,23DK3@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
k59_779939_1	1121439.dsat_0931	1.77e-42	146.0	COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42VH6@68525|delta/epsilon subdivisions,2WPC4@28221|Deltaproteobacteria,2MBBV@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	PFAM DivIVA family protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
k59_271493_1	1121405.dsmv_3392	6.39e-41	140.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,42MCM@68525|delta/epsilon subdivisions,2WKRE@28221|Deltaproteobacteria,2MJ7J@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_349519_1	566466.NOR53_3608	7.39e-99	309.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1RYC0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Outer membrane receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_505915_1	1230460.C495_02310	9.09e-16	80.1	COG1028@1|root,arCOG01259@2157|Archaea,2XSWX@28890|Euryarchaeota,23TIB@183963|Halobacteria	183963|Halobacteria	I	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_701671_1	298386.PBPRA1860	6.12e-36	135.0	COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,1RP1B@1236|Gammaproteobacteria,1XSFF@135623|Vibrionales	135623|Vibrionales	C	COG2864 Cytochrome b subunit of formate dehydrogenase	fdnI	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_191277_1	314345.SPV1_05467	2.93e-130	385.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria	1224|Proteobacteria	Q	COG1233 Phytoene dehydrogenase and related proteins	-	-	1.3.99.23,5.2.1.13	ko:K09516,ko:K09835	ko00830,ko00906,ko01100,ko01110,map00830,map00906,map01100,map01110	M00097	R07163,R07512	RC01835,RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
k59_35216_1	565045.NOR51B_1970	1.05e-97	288.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1J4HC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
k59_935703_1	626887.J057_23810	4.21e-66	206.0	2DC7W@1|root,2ZD7C@2|Bacteria,1QU8S@1224|Proteobacteria,1S6MA@1236|Gammaproteobacteria,46BPC@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
k59_780055_1	1206743.BAGM01000106_gene3134	7.71e-05	50.1	COG0265@1|root,COG0265@2|Bacteria,2GJJ3@201174|Actinobacteria,4FWGG@85025|Nocardiaceae	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
k59_152268_1	323850.Shew_2125	8.96e-38	144.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,2Q8S4@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM Lytic transglycosylase catalytic	slt	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iETEC_1333.ETEC_4747,iPC815.YPO0452	SLT,SLT_L
k59_817700_1	1232437.KL661988_gene188	4.38e-27	111.0	COG1624@1|root,COG1624@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,2MIQR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
k59_1132772_2	221027.JO40_11085	1.68e-37	137.0	COG1235@1|root,COG1235@2|Bacteria,2J5C5@203691|Spirochaetes	203691|Spirochaetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
k59_1132781_1	60711.ENSCSAP00000014159	4.88e-99	298.0	COG0039@1|root,KOG1494@2759|Eukaryota,38EX2@33154|Opisthokonta,3BHCA@33208|Metazoa,3D186@33213|Bilateria,48648@7711|Chordata,4914A@7742|Vertebrata,3J9KT@40674|Mammalia,35BAZ@314146|Euarchontoglires,4MEVN@9443|Primates,364JN@314294|Cercopithecoidea	33208|Metazoa	C	Malate dehydrogenase	MDH2	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006091,GO:0006094,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006464,GO:0006473,GO:0006475,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019318,GO:0019319,GO:0019362,GO:0019538,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0031974,GO:0034641,GO:0036211,GO:0042802,GO:0042803,GO:0043170,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043621,GO:0043648,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046364,GO:0046483,GO:0046496,GO:0046554,GO:0046983,GO:0051087,GO:0051186,GO:0055086,GO:0055114,GO:0070013,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564,GO:1901576	1.1.1.37	ko:K00026	ko00020,ko00270,ko00620,ko00630,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00710,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00171	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_742261_2	1033802.SSPSH_003183	4.89e-20	91.3	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
k59_703207_1	9555.ENSPANP00000004164	1.24e-315	859.0	COG0148@1|root,KOG2670@2759|Eukaryota,38C66@33154|Opisthokonta,3BE2S@33208|Metazoa,3CU4G@33213|Bilateria,480BN@7711|Chordata,48V1P@7742|Vertebrata,3J1VU@40674|Mammalia,35E0A@314146|Euarchontoglires,4M70G@9443|Primates,366UZ@314294|Cercopithecoidea	33208|Metazoa	G	Enolase, C-terminal TIM barrel domain	ENO1	GO:0000015,GO:0000122,GO:0000165,GO:0000976,GO:0000977,GO:0000981,GO:0000982,GO:0001012,GO:0001067,GO:0001078,GO:0001227,GO:0001558,GO:0001666,GO:0001701,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003723,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0005938,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006937,GO:0006950,GO:0007154,GO:0007165,GO:0007275,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009790,GO:0009792,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010648,GO:0010755,GO:0010756,GO:0010941,GO:0010954,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0019897,GO:0019898,GO:0019899,GO:0022607,GO:0023014,GO:0023051,GO:0023052,GO:0023057,GO:0030162,GO:0030308,GO:0030424,GO:0030426,GO:0030427,GO:0030808,GO:0030810,GO:0031072,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032787,GO:0032991,GO:0033267,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035556,GO:0036211,GO:0036293,GO:0036294,GO:0040008,GO:0042221,GO:0042802,GO:0042803,GO:0042866,GO:0042981,GO:0042995,GO:0043005,GO:0043009,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043207,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0043565,GO:0043933,GO:0044057,GO:0044085,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044425,GO:0044444,GO:0044445,GO:0044448,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045121,GO:0045202,GO:0045862,GO:0045892,GO:0045926,GO:0045933,GO:0045934,GO:0045935,GO:0045937,GO:0045981,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0046982,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051098,GO:0051099,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051186,GO:0051188,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051259,GO:0051262,GO:0051290,GO:0051291,GO:0051704,GO:0051707,GO:0051716,GO:0055086,GO:0055114,GO:0060255,GO:0060548,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0062012,GO:0062013,GO:0065003,GO:0065007,GO:0065009,GO:0070371,GO:0070482,GO:0070613,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0080135,GO:0090257,GO:0090407,GO:0097060,GO:0097159,GO:0097458,GO:0098589,GO:0098590,GO:0098805,GO:0098857,GO:0099568,GO:0099738,GO:0120025,GO:0120038,GO:0140110,GO:0150034,GO:1900037,GO:1900038,GO:1900371,GO:1900373,GO:1900542,GO:1900544,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494,GO:1902531,GO:1902532,GO:1902679,GO:1903297,GO:1903298,GO:1903317,GO:1903319,GO:1903506,GO:1903507,GO:1903578,GO:1903580,GO:1990837,GO:2000112,GO:2000113,GO:2001141,GO:2001169,GO:2001171,GO:2001233,GO:2001234,GO:2001242,GO:2001243	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_781460_1	631362.Thi970DRAFT_04432	2.83e-115	345.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,1T2D1@1236|Gammaproteobacteria,1X28U@135613|Chromatiales	135613|Chromatiales	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger
k59_153603_1	1499967.BAYZ01000013_gene6453	7.14e-28	108.0	2CC7H@1|root,32RJ0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_311685_1	96561.Dole_1428	3.33e-47	159.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42UBZ@68525|delta/epsilon subdivisions,2WNB6@28221|Deltaproteobacteria,2MJXY@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM Sua5 YciO YrdC YwlC family protein	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
k59_1056903_1	870187.Thini_2804	1.01e-75	250.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,45ZUX@72273|Thiotrichales	72273|Thiotrichales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_192695_1	391615.ABSJ01000022_gene293	4.9e-85	277.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1J4YP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB
k59_937263_1	335543.Sfum_0478	3.09e-144	433.0	COG0031@1|root,COG0215@1|root,COG0031@2|Bacteria,COG0215@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria,2MR3Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Pyridoxal-phosphate dependent enzyme	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
k59_36633_1	1247963.JPHU01000002_gene2506	3.59e-48	163.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
k59_36633_2	1210884.HG799466_gene12431	1.76e-38	141.0	COG0119@1|root,COG0119@2|Bacteria,2IX7Z@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_899512_1	1479237.JMLY01000001_gene2032	7.51e-77	247.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,464J7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0405 Gamma-glutamyltransferase	ggt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	iAPECO1_1312.APECO1_3012,iECOK1_1307.ECOK1_3869,iECS88_1305.ECS88_3844,iECW_1372.ECW_m3706,iEKO11_1354.EKO11_0296,iETEC_1333.ETEC_3693,iUMN146_1321.UM146_17325,iUTI89_1310.UTI89_C3954,iWFL_1372.ECW_m3706	G_glu_transpept
k59_819231_1	1121287.AUMU01000017_gene59	1.67e-28	109.0	2CCV8@1|root,2Z7KX@2|Bacteria,4NMFI@976|Bacteroidetes,1I1H9@117743|Flavobacteriia	976|Bacteroidetes	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
k59_351104_1	338963.Pcar_2585	4.89e-53	187.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,43RXX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
k59_391390_1	96561.Dole_0120	3.92e-13	68.2	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,2MIKI@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
k59_391390_2	96561.Dole_0121	3.72e-68	229.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,2MHQD@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase large chain oligomerisation	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
k59_899540_1	1121875.KB907546_gene2208	1e-13	76.3	COG1680@1|root,COG1680@2|Bacteria,4PI69@976|Bacteroidetes,1I0GH@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_859561_1	196367.JNFG01000209_gene256	1.04e-36	141.0	COG5421@1|root,COG5421@2|Bacteria,1R25F@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4277
k59_859564_1	1042377.AFPJ01000051_gene87	4.6e-87	271.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,46DHJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Sulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_507477_1	1249627.D779_4215	2.21e-52	186.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1WWWW@135613|Chromatiales	135613|Chromatiales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_625571_1	455436.DS989810_gene265	1.11e-21	98.2	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,1RR99@1236|Gammaproteobacteria,464X5@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
k59_36689_1	109478.XP_005862397.1	7.84e-213	592.0	KOG0279@1|root,KOG0279@2759|Eukaryota,38BFC@33154|Opisthokonta,3BE2C@33208|Metazoa,3CUEX@33213|Bilateria,485MP@7711|Chordata,48XIE@7742|Vertebrata,3J3CQ@40674|Mammalia,4M0UV@9397|Chiroptera	33208|Metazoa	T	Guanine nucleotide-binding protein subunit beta-2-like 1	GNB2L1	GO:0000003,GO:0000278,GO:0000280,GO:0000281,GO:0000375,GO:0000377,GO:0000398,GO:0000775,GO:0000776,GO:0000902,GO:0000904,GO:0000910,GO:0001525,GO:0001558,GO:0001568,GO:0001678,GO:0001891,GO:0001932,GO:0001933,GO:0001934,GO:0001944,GO:0001959,GO:0002009,GO:0003006,GO:0003254,GO:0003674,GO:0004857,GO:0004860,GO:0005080,GO:0005102,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005773,GO:0005776,GO:0005813,GO:0005815,GO:0005829,GO:0005840,GO:0005856,GO:0005886,GO:0005979,GO:0006109,GO:0006139,GO:0006396,GO:0006397,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006469,GO:0006518,GO:0006725,GO:0006807,GO:0006914,GO:0006915,GO:0006919,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006996,GO:0007033,GO:0007049,GO:0007059,GO:0007143,GO:0007154,GO:0007165,GO:0007186,GO:0007205,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007369,GO:0007399,GO:0007409,GO:0007411,GO:0007444,GO:0007610,GO:0007626,GO:0008045,GO:0008047,GO:0008064,GO:0008104,GO:0008150,GO:0008152,GO:0008200,GO:0008219,GO:0008380,GO:0008656,GO:0009056,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009607,GO:0009620,GO:0009653,GO:0009743,GO:0009746,GO:0009749,GO:0009790,GO:0009792,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0009991,GO:0010033,GO:0010467,GO:0010468,GO:0010470,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0010638,GO:0010646,GO:0010647,GO:0010648,GO:0010675,GO:0010676,GO:0010803,GO:0010906,GO:0010907,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0010962,GO:0012501,GO:0012505,GO:0015630,GO:0015935,GO:0016020,GO:0016032,GO:0016043,GO:0016070,GO:0016071,GO:0016236,GO:0016243,GO:0016247,GO:0016248,GO:0016504,GO:0016505,GO:0016567,GO:0017148,GO:0018991,GO:0019080,GO:0019081,GO:0019098,GO:0019207,GO:0019210,GO:0019216,GO:0019220,GO:0019222,GO:0019538,GO:0019725,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019902,GO:0019903,GO:0019904,GO:0019953,GO:0022008,GO:0022402,GO:0022412,GO:0022414,GO:0022603,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030030,GO:0030100,GO:0030111,GO:0030154,GO:0030162,GO:0030178,GO:0030182,GO:0030234,GO:0030292,GO:0030308,GO:0030332,GO:0030334,GO:0030335,GO:0030424,GO:0030425,GO:0030426,GO:0030427,GO:0030496,GO:0030832,GO:0030833,GO:0030838,GO:0030971,GO:0031175,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031331,GO:0031334,GO:0031399,GO:0031400,GO:0031401,GO:0031667,GO:0031668,GO:0031669,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032268,GO:0032269,GO:0032270,GO:0032271,GO:0032273,GO:0032434,GO:0032436,GO:0032446,GO:0032459,GO:0032461,GO:0032462,GO:0032464,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032878,GO:0032879,GO:0032880,GO:0032881,GO:0032885,GO:0032947,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033135,GO:0033137,GO:0033206,GO:0033267,GO:0033365,GO:0033500,GO:0033554,GO:0033673,GO:0034248,GO:0034249,GO:0034250,GO:0034284,GO:0034613,GO:0034641,GO:0034645,GO:0035220,GO:0035239,GO:0035295,GO:0035556,GO:0035591,GO:0035821,GO:0036211,GO:0036477,GO:0038023,GO:0040008,GO:0040011,GO:0040012,GO:0040017,GO:0040019,GO:0040038,GO:0042169,GO:0042176,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042330,GO:0042335,GO:0042391,GO:0042592,GO:0042593,GO:0042594,GO:0042802,GO:0042803,GO:0042981,GO:0042995,GO:0042996,GO:0042998,GO:0043005,GO:0043021,GO:0043022,GO:0043025,GO:0043028,GO:0043043,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043086,GO:0043087,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043255,GO:0043280,GO:0043281,GO:0043412,GO:0043467,GO:0043473,GO:0043547,GO:0043549,GO:0043603,GO:0043604,GO:0043900,GO:0043902,GO:0043903,GO:0044087,GO:0044089,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044297,GO:0044391,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044788,GO:0044794,GO:0044827,GO:0044829,GO:0044877,GO:0045069,GO:0045070,GO:0045725,GO:0045732,GO:0045806,GO:0045834,GO:0045859,GO:0045862,GO:0045913,GO:0045926,GO:0045936,GO:0045937,GO:0045995,GO:0046483,GO:0046716,GO:0046889,GO:0046890,GO:0046983,GO:0048285,GO:0048468,GO:0048471,GO:0048477,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048729,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050730,GO:0050732,GO:0050764,GO:0050765,GO:0050789,GO:0050790,GO:0050792,GO:0050793,GO:0050794,GO:0050801,GO:0050832,GO:0050896,GO:0051049,GO:0051050,GO:0051051,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051272,GO:0051301,GO:0051302,GO:0051304,GO:0051321,GO:0051336,GO:0051338,GO:0051342,GO:0051343,GO:0051345,GO:0051348,GO:0051493,GO:0051495,GO:0051641,GO:0051702,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0051817,GO:0051851,GO:0051881,GO:0051896,GO:0051898,GO:0051900,GO:0051901,GO:0052547,GO:0052548,GO:0055082,GO:0060026,GO:0060027,GO:0060089,GO:0060090,GO:0060249,GO:0060255,GO:0060341,GO:0060429,GO:0060548,GO:0060627,GO:0060759,GO:0061097,GO:0061099,GO:0061134,GO:0061136,GO:0061564,GO:0061640,GO:0061919,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070647,GO:0070727,GO:0070848,GO:0070873,GO:0070875,GO:0070887,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071363,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0072344,GO:0072358,GO:0072359,GO:0075522,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0090087,GO:0090153,GO:0090154,GO:0090304,GO:0097447,GO:0097458,GO:0097485,GO:0098542,GO:0098687,GO:0098772,GO:0099106,GO:0110053,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0140013,GO:0150034,GO:1900101,GO:1900102,GO:1900407,GO:1900408,GO:1901031,GO:1901032,GO:1901214,GO:1901215,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1901701,GO:1901800,GO:1902531,GO:1902532,GO:1902533,GO:1902882,GO:1902883,GO:1902903,GO:1902905,GO:1903046,GO:1903047,GO:1903050,GO:1903052,GO:1903076,GO:1903078,GO:1903201,GO:1903202,GO:1903203,GO:1903204,GO:1903205,GO:1903206,GO:1903207,GO:1903208,GO:1903362,GO:1903364,GO:1903573,GO:1903827,GO:1903829,GO:1903900,GO:1903902,GO:1904181,GO:1904375,GO:1904377,GO:1904951,GO:1905037,GO:1905038,GO:1905475,GO:1905477,GO:1905897,GO:1990630,GO:1990782,GO:1990904,GO:2000026,GO:2000058,GO:2000060,GO:2000112,GO:2000113,GO:2000114,GO:2000116,GO:2000145,GO:2000147,GO:2000303,GO:2000304,GO:2000543,GO:2001023,GO:2001024,GO:2001038,GO:2001039,GO:2001056,GO:2001233,GO:2001235,GO:2001242,GO:2001244	-	ko:K14753	ko05162,map05162	-	-	-	ko00000,ko00001,ko03019,ko04147	-	-	-	WD40
k59_467881_1	1283076.M1IP93_9CAUD	1.25e-27	115.0	4QAZ6@10239|Viruses,4QUU8@35237|dsDNA viruses  no RNA stage,4QPHV@28883|Caudovirales,4QI4H@10662|Myoviridae	10662|Myoviridae	S	Phage tail sheath protein	-	GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098027	-	-	-	-	-	-	-	-	-	-	-
k59_467887_1	1151061.CAJY01000018_gene3271	1.38e-15	82.4	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD3	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
k59_781653_1	9940.ENSOARP00000013846	9.47e-75	241.0	COG0443@1|root,KOG0100@2759|Eukaryota,38BPF@33154|Opisthokonta,3B99M@33208|Metazoa,3CZ71@33213|Bilateria,4817Y@7711|Chordata,48WW0@7742|Vertebrata,3JA4R@40674|Mammalia,4IXU5@91561|Cetartiodactyla	33208|Metazoa	O	Heat shock protein family A (Hsp70) member 5	HSPA5	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005783,GO:0005788,GO:0005789,GO:0005790,GO:0005793,GO:0005886,GO:0006355,GO:0006357,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006810,GO:0006915,GO:0006950,GO:0006983,GO:0006984,GO:0006986,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009057,GO:0009267,GO:0009314,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009719,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010042,GO:0010212,GO:0010243,GO:0010332,GO:0010466,GO:0010468,GO:0010498,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010648,GO:0010720,GO:0010941,GO:0010951,GO:0010975,GO:0010976,GO:0012501,GO:0012505,GO:0014070,GO:0014074,GO:0016020,GO:0016021,GO:0016246,GO:0016441,GO:0016458,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017015,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0019904,GO:0019941,GO:0021549,GO:0021575,GO:0021577,GO:0021587,GO:0021589,GO:0021680,GO:0021695,GO:0022008,GO:0022037,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030162,GO:0030163,GO:0030176,GO:0030182,GO:0030334,GO:0030335,GO:0030431,GO:0030433,GO:0030496,GO:0030512,GO:0030554,GO:0030902,GO:0030968,GO:0031047,GO:0031224,GO:0031227,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031344,GO:0031346,GO:0031396,GO:0031398,GO:0031399,GO:0031401,GO:0031625,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031984,GO:0032091,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032507,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032991,GO:0033036,GO:0033365,GO:0033554,GO:0034097,GO:0034613,GO:0034620,GO:0034663,GO:0034975,GO:0034976,GO:0035194,GO:0035437,GO:0035639,GO:0035690,GO:0035966,GO:0035967,GO:0036003,GO:0036094,GO:0036335,GO:0036498,GO:0036499,GO:0036500,GO:0036503,GO:0040012,GO:0040017,GO:0040019,GO:0040029,GO:0042149,GO:0042175,GO:0042220,GO:0042221,GO:0042493,GO:0042592,GO:0042594,GO:0042981,GO:0043021,GO:0043022,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043154,GO:0043161,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043279,GO:0043281,GO:0043393,GO:0043496,GO:0043618,GO:0043620,GO:0043632,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045185,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045861,GO:0045893,GO:0045935,GO:0045944,GO:0045995,GO:0046677,GO:0046683,GO:0046872,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048532,GO:0048583,GO:0048585,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048872,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051082,GO:0051087,GO:0051094,GO:0051098,GO:0051100,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051270,GO:0051272,GO:0051336,GO:0051346,GO:0051402,GO:0051591,GO:0051592,GO:0051603,GO:0051641,GO:0051651,GO:0051716,GO:0051787,GO:0051960,GO:0051962,GO:0052547,GO:0052548,GO:0060255,GO:0060284,GO:0060322,GO:0060359,GO:0060548,GO:0060904,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070670,GO:0070727,GO:0070848,GO:0070887,GO:0070972,GO:0070997,GO:0071214,GO:0071216,GO:0071236,GO:0071241,GO:0071248,GO:0071277,GO:0071287,GO:0071310,GO:0071320,GO:0071345,GO:0071353,GO:0071363,GO:0071407,GO:0071417,GO:0071478,GO:0071479,GO:0071480,GO:0071495,GO:0071496,GO:0071704,GO:0071944,GO:0072347,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0090074,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0097159,GO:0097367,GO:0097501,GO:0098827,GO:0104004,GO:0120035,GO:1900101,GO:1900102,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998,GO:1902074,GO:1902680,GO:1903320,GO:1903322,GO:1903332,GO:1903506,GO:1903508,GO:1903573,GO:1903844,GO:1903845,GO:1903891,GO:1903894,GO:1903895,GO:1903897,GO:1904313,GO:1905897,GO:1990089,GO:1990090,GO:1990440,GO:2000026,GO:2000112,GO:2000116,GO:2000117,GO:2000145,GO:2000147,GO:2001141	-	ko:K09490	ko03060,ko04141,ko04918,ko05020,map03060,map04141,map04918,map05020	-	-	-	ko00000,ko00001,ko03110,ko04131,ko04147	1.A.33	-	-	HSP70
k59_703434_1	760568.Desku_0313	5.69e-16	75.9	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
k59_703434_2	706587.Desti_1812	5.03e-72	229.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MQ86@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363	1.3.8.10,1.3.8.11	ko:K19066,ko:K19067	ko00362,ko01120,map00362,map01120	-	R09252,R10601	RC00248,RC02035	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3306	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_742493_1	443143.GM18_4059	1.13e-14	77.4	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,42P70@68525|delta/epsilon subdivisions,2WJGD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_937383_1	1127673.GLIP_1244	1.52e-60	201.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,464HF@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
k59_311875_1	1004785.AMBLS11_15790	1.62e-39	151.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1RGCV@1224|Proteobacteria,1SJP8@1236|Gammaproteobacteria,46D4G@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	PAS sensor diguanylate cyclase and	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,PilZ
k59_1151457_1	335543.Sfum_3600	4.46e-72	221.0	COG4871@1|root,COG4871@2|Bacteria,1RF0E@1224|Proteobacteria,42RKU@68525|delta/epsilon subdivisions,2WNHT@28221|Deltaproteobacteria,2MRPZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS
k59_132657_1	933262.AXAM01000004_gene2360	2.63e-67	215.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2MIMG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein, alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
k59_798337_1	338969.Rfer_1171	5.61e-16	77.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2VWYN@28216|Betaproteobacteria,4AFWS@80864|Comamonadaceae	28216|Betaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_171980_1	584708.Apau_0585	1.07e-35	133.0	COG3039@1|root,COG3039@2|Bacteria,3TBCF@508458|Synergistetes	508458|Synergistetes	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_409323_1	247639.MGP2080_07012	2.52e-42	154.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
k59_409323_2	1408418.JNJH01000027_gene559	1.21e-05	47.4	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2JPRP@204441|Rhodospirillales	204441|Rhodospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1190991_1	794903.OPIT5_11485	5.27e-05	45.4	COG0846@1|root,COG0846@2|Bacteria,46V8Q@74201|Verrucomicrobia,3K838@414999|Opitutae	414999|Opitutae	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k59_1190991_2	177437.HRM2_26890	1.64e-50	171.0	COG0189@1|root,COG0189@2|Bacteria,1MWQA@1224|Proteobacteria,43B1R@68525|delta/epsilon subdivisions,2X6FW@28221|Deltaproteobacteria,2MJ6I@213118|Desulfobacterales	28221|Deltaproteobacteria	HJ	RimK-like ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
k59_1037216_1	247633.GP2143_04173	2.85e-36	138.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_211337_1	61647.LG71_23620	5.69e-19	89.7	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,1RPPC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC-type Fe3 transport system, periplasmic component	HA62_21480	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
k59_1037240_1	1121405.dsmv_0555	1.33e-75	246.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2MINC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
k59_838137_1	1380370.JIBA01000003_gene2760	5.81e-46	168.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4FE2Y@85021|Intrasporangiaceae	201174|Actinobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Inhibitor_I9,PA,PPC,Peptidase_S8
k59_1151540_1	648757.Rvan_1643	1.89e-101	307.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3N6EF@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_603572_1	335543.Sfum_2508	3.05e-43	155.0	2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,42Q4T@68525|delta/epsilon subdivisions,2WK9F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_250764_1	335543.Sfum_3750	2.35e-100	315.0	COG0673@1|root,COG3494@1|root,COG0673@2|Bacteria,COG3494@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,2MR8J@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
k59_997877_1	78245.Xaut_0592	3.83e-182	521.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TTBA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_681535_1	1232437.KL662077_gene1941	2.4e-144	421.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,43BQX@68525|delta/epsilon subdivisions,2X71W@28221|Deltaproteobacteria,2MIFV@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_642140_1	1187848.AJYQ01000003_gene410	4.7e-114	342.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGA@1236|Gammaproteobacteria,1XXNF@135623|Vibrionales	135623|Vibrionales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_94664_1	1454004.AW11_02009	3.94e-135	406.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2VIFW@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Pfam Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_838170_1	314278.NB231_07442	6.35e-16	77.4	2E3RZ@1|root,32YPK@2|Bacteria,1NJYT@1224|Proteobacteria,1SHP1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_838170_2	373994.Riv7116_4828	3.33e-30	117.0	COG0604@1|root,COG0604@2|Bacteria,1G4D5@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_1037315_1	177437.HRM2_18710	4.94e-39	147.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2MHM6@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_290060_1	1205680.CAKO01000002_gene3064	4.5e-57	193.0	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,2JQU6@204441|Rhodospirillales	204441|Rhodospirillales	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
k59_1151605_1	61853.ENSNLEP00000020499	1.68e-120	351.0	KOG3151@1|root,KOG3151@2759|Eukaryota,38EJH@33154|Opisthokonta,3BF0S@33208|Metazoa,3CSPR@33213|Bilateria,4821W@7711|Chordata,48YP1@7742|Vertebrata,3J9UI@40674|Mammalia,35ESG@314146|Euarchontoglires,4MGY4@9443|Primates	33208|Metazoa	O	Proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	PSMD8	GO:0000502,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0008541,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016043,GO:0016579,GO:0019538,GO:0019941,GO:0022607,GO:0022624,GO:0030163,GO:0031974,GO:0031981,GO:0032991,GO:0034622,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043687,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0051603,GO:0065003,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	-	ko:K03031	ko03050,ko05169,map03050,map05169	M00341	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	CSN8_PSD8_EIF3K
k59_642190_1	876044.IMCC3088_1349	3.67e-14	77.4	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1J4N1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1	comC	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,VWA_2
k59_1072958_1	744980.TRICHSKD4_4685	5.34e-47	152.0	COG2963@1|root,COG2963@2|Bacteria,1RGZ5@1224|Proteobacteria,2UAIS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_721167_1	1002340.AFCF01000007_gene2910	3.55e-10	60.5	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,2TRM7@28211|Alphaproteobacteria,34G9N@302485|Phaeobacter	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	soxB2	-	1.5.3.1,1.5.99.5	ko:K00303,ko:K22084	ko00260,ko00680,ko01100,ko01120,map00260,map00680,map01100,map01120	-	R00609,R00610	RC00060,RC00190,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
k59_290091_1	717785.HYPMC_1643	2.3e-14	71.2	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2TT2D@28211|Alphaproteobacteria,3N6CT@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	H	Sulfate adenylyltransferase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_290091_2	1267005.KB911258_gene266	3.08e-71	222.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2U5AP@28211|Alphaproteobacteria,3N74K@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
k59_54211_1	1120948.KB903244_gene2929	6.07e-14	77.8	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DYY0@85010|Pseudonocardiales	201174|Actinobacteria	CK	Acyl-CoA synthetase (NDP forming)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_997969_1	396588.Tgr7_0796	8.59e-27	117.0	COG0457@1|root,COG0457@2|Bacteria,1R50I@1224|Proteobacteria,1S4B5@1236|Gammaproteobacteria,1X26Z@135613|Chromatiales	135613|Chromatiales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_681612_1	391615.ABSJ01000050_gene1141	5.18e-36	132.0	COG3306@1|root,COG3306@2|Bacteria,1RFMG@1224|Proteobacteria,1SGZD@1236|Gammaproteobacteria,1JBB0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase family 25 (LPS biosynthesis protein)	-	-	-	ko:K07270	-	-	-	-	ko00000	-	GT25	-	Glyco_transf_25
k59_759694_2	797304.Natgr_0798	3.7e-06	51.2	COG0601@1|root,arCOG00751@2157|Archaea,2XU2Z@28890|Euryarchaeota,23SGH@183963|Halobacteria	183963|Halobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_527434_1	1121405.dsmv_1663	2.06e-60	200.0	COG5557@1|root,COG5557@2|Bacteria,1QURB@1224|Proteobacteria,43BT1@68525|delta/epsilon subdivisions,2X73S@28221|Deltaproteobacteria,2MMX3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pfam Polysulphide reductase, NrfD	actF	-	-	-	-	-	-	-	-	-	-	-	-
k59_331046_1	1415778.JQMM01000001_gene538	1.27e-84	265.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria,1J4I5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	gtrB	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_448670_1	59538.XP_005955895.1	1.63e-68	217.0	COG0580@1|root,KOG0223@2759|Eukaryota,39WNG@33154|Opisthokonta,3BGGI@33208|Metazoa,3D0UE@33213|Bilateria,48QXA@7711|Chordata,49MH8@7742|Vertebrata,3JPWG@40674|Mammalia	33208|Metazoa	G	Major intrinsic protein	-	-	-	ko:K09866,ko:K09867,ko:K09884	ko04962,ko04970,ko04976,map04962,map04970,map04976	-	-	-	ko00000,ko00001,ko02000	1.A.8	-	-	MIP
k59_412532_1	396588.Tgr7_2026	2.29e-28	120.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1WW7V@135613|Chromatiales	135613|Chromatiales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_448682_1	1333507.AUTQ01000261_gene3824	1.75e-107	325.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	iEcE24377_1341.EcE24377A_1810	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
k59_1153880_1	589865.DaAHT2_0466	8.76e-43	150.0	COG1215@1|root,COG1215@2|Bacteria,1RIJ7@1224|Proteobacteria,42WPQ@68525|delta/epsilon subdivisions,2WV8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1153891_1	1094980.Mpsy_2614	4.4e-29	119.0	COG1331@1|root,arCOG02007@2157|Archaea,2XU5Q@28890|Euryarchaeota,2N91Y@224756|Methanomicrobia	224756|Methanomicrobia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
k59_683931_1	1121456.ATVA01000016_gene2069	8.16e-08	53.1	2AT6X@1|root,31IPI@2|Bacteria,1NNR6@1224|Proteobacteria,42WTE@68525|delta/epsilon subdivisions,2WTHD@28221|Deltaproteobacteria,2MC0J@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_958303_1	376733.IT41_06000	6.98e-26	113.0	COG1289@1|root,COG1289@2|Bacteria	2|Bacteria	S	transmembrane transporter activity	VPA1578	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_879749_1	582899.Hden_2756	2.64e-42	153.0	COG2177@1|root,COG2177@2|Bacteria,1MXKQ@1224|Proteobacteria,2TSNT@28211|Alphaproteobacteria,3N6YI@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	D	Cell division protein	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
k59_723344_1	9606.ENSP00000237530	1.53e-224	632.0	KOG2447@1|root,KOG2447@2759|Eukaryota,38C03@33154|Opisthokonta,3BAZG@33208|Metazoa,3CU2K@33213|Bilateria,4811D@7711|Chordata,49481@7742|Vertebrata,3J4SG@40674|Mammalia,35CMJ@314146|Euarchontoglires,4MA03@9443|Primates,4MS8C@9604|Hominidae	33208|Metazoa	O	protein N-linked glycosylation	RPN2	GO:0000421,GO:0002252,GO:0002376,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005776,GO:0005783,GO:0005789,GO:0005791,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0006996,GO:0007029,GO:0007568,GO:0008150,GO:0008152,GO:0008250,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010256,GO:0012505,GO:0016020,GO:0016043,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0031090,GO:0031984,GO:0032502,GO:0032991,GO:0034645,GO:0035010,GO:0036211,GO:0042175,GO:0042221,GO:0042493,GO:0043021,GO:0043022,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051302,GO:0065007,GO:0070085,GO:0071704,GO:0071840,GO:0098588,GO:0098796,GO:0098805,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990234	-	ko:K12667	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	-	-	ko00000,ko00001,ko00002	-	-	-	Ribophorin_II
k59_17541_1	1123298.KB904121_gene1917	5.73e-09	60.5	COG0582@1|root,COG0582@2|Bacteria,1UMEE@1239|Firmicutes,4ITVG@91061|Bacilli	91061|Bacilli	L	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
k59_1039980_1	318161.Sden_2243	8.66e-10	59.3	2E9KN@1|root,333TE@2|Bacteria,1NCTP@1224|Proteobacteria,1SFMQ@1236|Gammaproteobacteria,2QCVA@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_56404_1	1265505.ATUG01000002_gene2078	1.25e-71	222.0	COG1014@1|root,COG1014@2|Bacteria,1RBZA@1224|Proteobacteria,42QT3@68525|delta/epsilon subdivisions,2X6H9@28221|Deltaproteobacteria,2MJ4W@213118|Desulfobacterales	28221|Deltaproteobacteria	C	indolepyruvate ferredoxin oxidoreductase, beta subunit	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
k59_56404_2	335543.Sfum_4075	1.64e-28	114.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,2MR22@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
k59_1039985_1	697282.Mettu_1351	1.09e-100	301.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,1XDXQ@135618|Methylococcales	135618|Methylococcales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_331114_1	501479.ACNW01000062_gene2740	1.31e-108	330.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_566340_1	395495.Lcho_4123	1.7e-62	216.0	COG3303@1|root,COG3303@2|Bacteria,1PEVM@1224|Proteobacteria,2VMWI@28216|Betaproteobacteria,1KN2G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_253228_1	335543.Sfum_1766	1.05e-27	112.0	COG2896@1|root,COG2896@2|Bacteria,1MXMH@1224|Proteobacteria,42NTM@68525|delta/epsilon subdivisions,2WKIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
k59_918246_1	1333856.L686_12380	1.22e-83	261.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,1RQVT@1236|Gammaproteobacteria,1Z1TJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_448766_1	396588.Tgr7_2336	2.81e-83	249.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,1WWG3@135613|Chromatiales	135613|Chromatiales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
k59_448766_2	743720.Psefu_0627	3.23e-12	64.3	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1YYMR@136845|Pseudomonas putida group	1236|Gammaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
k59_56445_1	998088.B565_2754	4.54e-07	50.8	COG0446@1|root,COG0446@2|Bacteria,1QUQF@1224|Proteobacteria,1RP1H@1236|Gammaproteobacteria,1Y5DM@135624|Aeromonadales	135624|Aeromonadales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1001081_2	429009.Adeg_1595	2.13e-31	120.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,42ESB@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k59_331166_1	269799.Gmet_1174	2.32e-25	118.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,43T01@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_1235573_1	522306.CAP2UW1_3926	1.01e-47	176.0	COG2885@1|root,COG2982@1|root,COG2885@2|Bacteria,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,1KQU2@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
k59_17618_1	335543.Sfum_2328	1.08e-76	239.0	COG0189@1|root,COG0189@2|Bacteria,1QX79@1224|Proteobacteria,42P6H@68525|delta/epsilon subdivisions,2WKP1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HJ	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
k59_1075180_1	1469557.JSWF01000033_gene1646	2.54e-143	417.0	2DV1D@1|root,33THT@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_1075180_2	118161.KB235922_gene387	8.5e-74	241.0	COG5361@1|root,COG5361@2|Bacteria,1GIK1@1117|Cyanobacteria,3VMQJ@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_292667_1	1173022.Cri9333_3081	4.77e-17	85.1	COG0687@1|root,COG0687@2|Bacteria,1G0DM@1117|Cyanobacteria,1H8MN@1150|Oscillatoriales	1117|Cyanobacteria	E	Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
k59_1193532_1	1267005.KB911255_gene2489	2.06e-43	149.0	COG3806@1|root,COG3806@2|Bacteria,1RI6T@1224|Proteobacteria,2TVH9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	anti-sigma factor	chrR	-	-	ko:K07167	-	-	-	-	ko00000	-	-	-	Cupin_7,zf-HC2
k59_1154023_1	1382356.JQMP01000001_gene1147	1.98e-48	170.0	COG0683@1|root,COG0683@2|Bacteria,2G7TX@200795|Chloroflexi,27YY0@189775|Thermomicrobia	189775|Thermomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_412747_1	574966.KB898653_gene1402	1.03e-20	91.7	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,1XHA1@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
k59_412747_2	713586.KB900536_gene2316	8.23e-05	44.3	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_762090_1	1158292.JPOE01000005_gene68	1.98e-09	65.1	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,1KJ24@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Signal transducing histidine kinase, homodimeric domain	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_800758_1	1121396.KB892954_gene3520	4.21e-78	235.0	COG3791@1|root,COG3791@2|Bacteria,1PSHI@1224|Proteobacteria,42WTX@68525|delta/epsilon subdivisions,2WT7S@28221|Deltaproteobacteria,2MNCF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_527634_1	1121405.dsmv_1067	1.45e-73	228.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,2MJHY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_1235636_1	1168289.AJKI01000051_gene820	3.66e-121	359.0	COG4277@1|root,COG4277@2|Bacteria,4NEI2@976|Bacteroidetes,2FNIC@200643|Bacteroidia	976|Bacteroidetes	S	DNA-binding protein with the Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
k59_17662_1	56780.SYN_02850	1.54e-37	135.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2MQCF@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
k59_1235642_1	935261.JAGL01000009_gene1165	2.38e-107	332.0	COG0209@1|root,COG0209@2|Bacteria,1PM78@1224|Proteobacteria,2UZUM@28211|Alphaproteobacteria,43QGW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_371042_1	342113.DM82_818	7.18e-40	147.0	COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,2VMM5@28216|Betaproteobacteria,1K1QB@119060|Burkholderiaceae	28216|Betaproteobacteria	V	MATE efflux family protein	dinF	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_311620_1	999611.KI421504_gene494	3.6e-40	148.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria,282GA@191028|Leisingera	28211|Alphaproteobacteria	L	Integrase core domain	istA	-	-	-	-	-	-	-	-	-	-	-	rve
k59_311630_1	1121374.KB891575_gene1632	1.96e-14	69.7	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S4GX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
k59_311630_2	1085623.GNIT_2803	0.00012	47.4	COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria,464BN@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_350945_1	981384.AEYW01000004_gene1772	2.34e-18	86.7	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,4NCZP@97050|Ruegeria	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_350947_2	243277.VC_A0136	9.66e-56	185.0	COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,1RRBP@1236|Gammaproteobacteria,1XV2F@135623|Vibrionales	135623|Vibrionales	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_585880_1	1121405.dsmv_1693	1.75e-55	181.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,2MMB5@213118|Desulfobacterales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
k59_742261_1	637905.SVI_0305	0.00032	42.7	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,2QAIS@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
k59_159324_1	1121405.dsmv_1660	1.66e-43	149.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,42NZG@68525|delta/epsilon subdivisions,2WNX9@28221|Deltaproteobacteria,2MKZC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	cytochrome C oxidase mono-heme subunit FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixO
k59_903787_1	1298608.JCM18900_11542	5.9e-33	130.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,3NK7J@468|Moraxellaceae	1236|Gammaproteobacteria	I	Phospholipase D	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_41724_1	674977.VMC_01270	2.34e-78	248.0	COG1249@1|root,COG1249@2|Bacteria,1MXQ3@1224|Proteobacteria,1RQ44@1236|Gammaproteobacteria,1XUDY@135623|Vibrionales	135623|Vibrionales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_1217126_1	1131269.AQVV01000005_gene410	4.6e-40	144.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_629551_1	613026.HRAG_00094	7.09e-14	75.9	COG4866@1|root,COG4866@2|Bacteria,1RIUZ@1224|Proteobacteria,42P4H@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	conserved protein	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
k59_512281_2	296591.Bpro_0144	1.08e-67	207.0	COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,2VSJM@28216|Betaproteobacteria,4AEJT@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_2965_1	768671.ThimaDRAFT_4175	5.87e-70	235.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1WXPW@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
k59_1021700_2	1121405.dsmv_1271	1.98e-66	214.0	COG0589@1|root,COG0589@2|Bacteria,1NY54@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_120337_1	314232.SKA53_08201	1.97e-52	174.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,2P8WK@245186|Loktanella	28211|Alphaproteobacteria	C	Cytochrome bd terminal oxidase subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k59_120337_2	1537715.JQFJ01000002_gene2262	5.06e-42	151.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,2TQMA@28211|Alphaproteobacteria,2K0ZR@204457|Sphingomonadales	204457|Sphingomonadales	C	oxidase, subunit	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k59_237712_1	203122.Sde_1632	3.53e-19	89.4	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,467J1@72275|Alteromonadaceae	1236|Gammaproteobacteria	EH	COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	pabC	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_177,iE2348C_1286.E2348C_1188,iECED1_1282.ECED1_1239,iECNA114_1301.ECNA114_1153,iECOK1_1307.ECOK1_1203,iECS88_1305.ECS88_1110,iECSF_1327.ECSF_0995,iECUMN_1333.ECUMN_1273,iJN746.PP_1917,iPC815.YPO1603,iUMN146_1321.UM146_11845,iUTI89_1310.UTI89_C1222,ic_1306.c1366	Aminotran_4
k59_198631_2	207954.MED92_02656	1.21e-32	117.0	COG3450@1|root,COG3450@2|Bacteria,1N0F7@1224|Proteobacteria,1SCE6@1236|Gammaproteobacteria,1XS8B@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF861)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_3
k59_668839_1	1322246.BN4_20230	8.97e-10	58.9	COG4659@1|root,COG4659@2|Bacteria,1PPK1@1224|Proteobacteria,42TAI@68525|delta/epsilon subdivisions,2WNZU@28221|Deltaproteobacteria,2M9S6@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k59_668839_2	96561.Dole_2829	4.77e-55	181.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,42QE5@68525|delta/epsilon subdivisions,2WM8R@28221|Deltaproteobacteria,2MHVT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_2992_1	1134474.O59_003846	3.27e-45	156.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,1FI7A@10|Cellvibrio	1236|Gammaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_903858_1	794903.OPIT5_08990	3.01e-43	152.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	glpQ	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	iECNA114_1301.ECNA114_2331,iECSF_1327.ECSF_2119	GDPD
k59_943209_1	1121405.dsmv_2750	1.18e-84	265.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2MIZ1@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Starch synthase catalytic	-	-	2.4.1.21,3.2.1.1	ko:K00703,ko:K01176	ko00500,ko01100,ko01110,ko02026,ko04973,map00500,map01100,map01110,map02026,map04973	M00565	R02108,R02112,R02421,R11262	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GH13,GT5	-	Glyco_trans_1_4,Glyco_transf_5,Glycos_transf_1
k59_707889_1	1121013.P873_05830	4.16e-32	120.0	COG3339@1|root,COG3339@2|Bacteria,1RAN7@1224|Proteobacteria,1S291@1236|Gammaproteobacteria,1X60S@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
k59_3031_1	1121405.dsmv_3816	3.46e-143	423.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,2MHSF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
k59_198681_1	1304885.AUEY01000036_gene2244	2.23e-74	241.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,2MHSF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
k59_1178378_1	414684.RC1_3798	6.27e-79	253.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2TSHC@28211|Alphaproteobacteria,2JR9C@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
k59_355425_1	349124.Hhal_0884	1.09e-64	221.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1WWDE@135613|Chromatiales	135613|Chromatiales	T	Belongs to the PEP-utilizing enzyme family	-	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_433720_1	1123228.AUIH01000014_gene343	6.94e-38	137.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,1RNSM@1236|Gammaproteobacteria,1XHMJ@135619|Oceanospirillales	135619|Oceanospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_943235_1	96561.Dole_1488	8.84e-84	253.0	COG3640@1|root,COG3640@2|Bacteria,1R819@1224|Proteobacteria,42PQR@68525|delta/epsilon subdivisions,2WKE4@28221|Deltaproteobacteria,2MIKC@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
k59_943244_1	272123.Anacy_1230	2.24e-63	208.0	COG3335@1|root,COG3335@2|Bacteria,1G4FA@1117|Cyanobacteria,1HQ3V@1161|Nostocales	1117|Cyanobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
k59_551434_1	1122604.JONR01000001_gene1738	4.51e-72	231.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1X3ED@135614|Xanthomonadales	135614|Xanthomonadales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_629684_1	335543.Sfum_1067	3.47e-32	127.0	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,42MW1@68525|delta/epsilon subdivisions,2WJBE@28221|Deltaproteobacteria,2MQZ4@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_473000_1	443143.GM18_0341	2.47e-79	257.0	COG2133@1|root,COG2133@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_590697_1	1278309.KB907100_gene1888	6.67e-25	103.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1XHCG@135619|Oceanospirillales	135619|Oceanospirillales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_590697_2	998674.ATTE01000001_gene2133	4.92e-82	263.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,45ZVK@72273|Thiotrichales	72273|Thiotrichales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_943258_3	396588.Tgr7_1272	5.09e-22	87.0	COG0298@1|root,COG0298@2|Bacteria,1QKV6@1224|Proteobacteria,1SE6V@1236|Gammaproteobacteria,1WZDC@135613|Chromatiales	135613|Chromatiales	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
k59_943260_1	96561.Dole_1063	1.52e-59	197.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2MHQF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
k59_1178417_1	27679.XP_010331238.1	1.38e-175	497.0	KOG0118@1|root,KOG0118@2759|Eukaryota,39ST6@33154|Opisthokonta,3BA81@33208|Metazoa,3CRMB@33213|Bilateria,485HG@7711|Chordata,48V1Y@7742|Vertebrata,3J4FY@40674|Mammalia,359NG@314146|Euarchontoglires,4M95K@9443|Primates	33208|Metazoa	A	cellular response to sodium arsenite	HNRNPA1	GO:0000003,GO:0000375,GO:0000377,GO:0000380,GO:0000381,GO:0000398,GO:0000733,GO:0000781,GO:0000785,GO:0000792,GO:0001654,GO:0001745,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0003725,GO:0003727,GO:0003729,GO:0003730,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005694,GO:0005700,GO:0005703,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0006810,GO:0006913,GO:0006950,GO:0006996,GO:0007044,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007423,GO:0007548,GO:0008134,GO:0008150,GO:0008152,GO:0008380,GO:0008406,GO:0008584,GO:0008585,GO:0009266,GO:0009408,GO:0009605,GO:0009628,GO:0009635,GO:0009636,GO:0009653,GO:0009719,GO:0009887,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0014070,GO:0016032,GO:0016043,GO:0016070,GO:0016071,GO:0016462,GO:0016604,GO:0016607,GO:0016787,GO:0016817,GO:0016818,GO:0017085,GO:0017111,GO:0019048,GO:0019087,GO:0019219,GO:0019222,GO:0019827,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0030154,GO:0030323,GO:0030324,GO:0030718,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031581,GO:0031667,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032392,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033119,GO:0033592,GO:0033993,GO:0034248,GO:0034250,GO:0034329,GO:0034330,GO:0034641,GO:0035062,GO:0035198,GO:0035295,GO:0035690,GO:0035821,GO:0035864,GO:0035865,GO:0036099,GO:0036310,GO:0042221,GO:0042391,GO:0042493,GO:0042594,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043484,GO:0043565,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0044703,GO:0045137,GO:0045727,GO:0045760,GO:0045934,GO:0046483,GO:0046545,GO:0046546,GO:0046660,GO:0046661,GO:0046677,GO:0046685,GO:0046907,GO:0048024,GO:0048027,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048592,GO:0048608,GO:0048609,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050684,GO:0050789,GO:0050794,GO:0050896,GO:0051168,GO:0051169,GO:0051170,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051276,GO:0051641,GO:0051649,GO:0051701,GO:0051704,GO:0051716,GO:0051817,GO:0060255,GO:0060541,GO:0061458,GO:0061980,GO:0065007,GO:0065008,GO:0070013,GO:0070848,GO:0070849,GO:0070887,GO:0071103,GO:0071236,GO:0071241,GO:0071243,GO:0071248,GO:0071310,GO:0071363,GO:0071364,GO:0071396,GO:0071407,GO:0071495,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090596,GO:0097159,GO:0097237,GO:0097327,GO:0097617,GO:0098687,GO:0098727,GO:0098900,GO:0140097,GO:1901360,GO:1901363,GO:1901700,GO:1901701,GO:1902074,GO:1902075,GO:1903311,GO:1903935,GO:1903936,GO:1904576,GO:1904577,GO:1904578,GO:1904579,GO:1990825,GO:1990826,GO:1990904,GO:2000112	-	ko:K12741,ko:K13158,ko:K14411	ko03015,ko03040,map03015,map03040	-	-	-	ko00000,ko00001,ko03019,ko03041,ko04147	-	-	-	HnRNPA1,RRM_1
k59_1178419_1	593907.Celgi_1998	4.06e-24	105.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4F0N6@85016|Cellulomonadaceae	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1099993_1	706587.Desti_5090	1.71e-84	265.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,2MQZ3@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.34	ko:K00666,ko:K12508	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1217273_1	335543.Sfum_0020	7.56e-110	341.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2MQ92@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_1021895_1	1123367.C666_14390	5.84e-96	286.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,2VNNF@28216|Betaproteobacteria,2KVHD@206389|Rhodocyclales	206389|Rhodocyclales	I	Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_1178442_1	1004785.AMBLS11_14550	1.38e-26	109.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,1T3TQ@1236|Gammaproteobacteria,464MA@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_903966_1	1121405.dsmv_2245	6.56e-75	249.0	COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,42N23@68525|delta/epsilon subdivisions,2WKW2@28221|Deltaproteobacteria,2MHZB@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
k59_3130_1	565045.NOR51B_699	9.27e-81	247.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1J591@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
k59_943306_1	335543.Sfum_1683	6.72e-99	299.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42NKD@68525|delta/epsilon subdivisions,2WIWV@28221|Deltaproteobacteria,2MR0M@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1825	AMP-binding,AMP-binding_C_2
k59_512492_1	1415779.JOMH01000001_gene3284	2.28e-114	343.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1X34C@135614|Xanthomonadales	135614|Xanthomonadales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
k59_395077_1	1179773.BN6_81150	2.26e-76	244.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4E1SB@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	4CL	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_1178456_1	1120983.KB894570_gene1818	2.55e-89	285.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2TR4E@28211|Alphaproteobacteria,1JNB4@119043|Rhodobiaceae	28211|Alphaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
k59_982686_1	1304874.JAFY01000002_gene661	3.07e-86	266.0	COG0477@1|root,COG2814@2|Bacteria,3TACG@508458|Synergistetes	508458|Synergistetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_943326_1	1260251.SPISAL_03170	2.37e-34	122.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1WY8Z@135613|Chromatiales	135613|Chromatiales	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_551488_1	1312959.KI914697_gene3241	5.49e-63	205.0	COG2801@1|root,COG2801@2|Bacteria,2I8Z0@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_237875_1	1313172.YM304_34520	4.93e-82	271.0	COG2374@1|root,COG2374@2|Bacteria,2I2E0@201174|Actinobacteria	201174|Actinobacteria	M	endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_3_5,Big_5,CW_binding_2,DUF3616,Exo_endo_phos,LTD
k59_277164_1	1121015.N789_09065	2.49e-09	63.2	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X5CR@135614|Xanthomonadales	135614|Xanthomonadales	NT	chemotaxis protein	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
k59_1139019_1	472759.Nhal_1427	6.34e-76	238.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,1S1QN@1236|Gammaproteobacteria,1WZC3@135613|Chromatiales	135613|Chromatiales	U	Type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
k59_159609_1	1353531.AZNX01000005_gene3261	2.23e-21	99.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2U4F6@28211|Alphaproteobacteria,4BCVF@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
k59_551528_1	237368.SCABRO_01651	1.51e-64	208.0	COG3464@1|root,COG3464@2|Bacteria,2J105@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
k59_316251_1	519989.ECTPHS_03784	9.31e-117	338.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria,1WX9I@135613|Chromatiales	135613|Chromatiales	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
k59_864959_1	713587.THITH_07430	4.71e-41	142.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
k59_864959_2	998088.B565_3072	2.13e-45	156.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1Y3GJ@135624|Aeromonadales	135624|Aeromonadales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
k59_3191_2	435908.IDSA_10385	8.64e-12	66.6	COG2182@1|root,COG2182@2|Bacteria,1MU3H@1224|Proteobacteria,1RY48@1236|Gammaproteobacteria,2QFRF@267893|Idiomarinaceae	1236|Gammaproteobacteria	G	Extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_747384_1	631362.Thi970DRAFT_02219	1.48e-59	201.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales	135613|Chromatiales	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_277222_1	1304275.C41B8_15862	4.57e-05	52.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
k59_316265_1	1348114.OM33_00815	1.07e-58	206.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q12B@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_551560_1	335543.Sfum_1550	8.25e-142	438.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MR5Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_825821_1	555088.DealDRAFT_1474	1.57e-34	126.0	COG2386@1|root,COG2386@2|Bacteria,1VDEP@1239|Firmicutes,24NJK@186801|Clostridia	186801|Clostridia	O	cytochrome c-type biogenesis protein CcmB	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
k59_825821_2	324602.Caur_0943	1.67e-10	60.5	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi,375MP@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
k59_747427_1	479434.Sthe_2164	5.44e-18	89.0	COG0243@1|root,COG0243@2|Bacteria,2G844@200795|Chloroflexi,27XFA@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
k59_943405_1	754477.Q7C_1379	6.7e-86	261.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,46018@72273|Thiotrichales	72273|Thiotrichales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
k59_1060728_1	96561.Dole_2374	8.03e-52	171.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2MJ7T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
k59_316294_1	1265505.ATUG01000002_gene1098	1.28e-12	67.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,2MP6C@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
k59_316294_2	706587.Desti_0876	1.77e-38	135.0	COG5012@1|root,COG5012@2|Bacteria,1PXIE@1224|Proteobacteria,42S38@68525|delta/epsilon subdivisions,2WNTX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
k59_457368_1	396588.Tgr7_1275	6.38e-90	274.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,1RRTQ@1236|Gammaproteobacteria,1WWD8@135613|Chromatiales	135613|Chromatiales	O	Belongs to the HypD family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
k59_1245375_1	1121405.dsmv_0971	2.76e-87	271.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2MHS6@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_496820_1	377629.TERTU_3251	9.23e-91	286.0	COG3425@1|root,COG3425@2|Bacteria,1MU4K@1224|Proteobacteria,1S16F@1236|Gammaproteobacteria,2PPKP@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	I	Hydroxymethylglutaryl-coenzyme A synthase N terminal	-	-	2.3.3.10	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
k59_496822_2	1122137.AQXF01000002_gene377	5.57e-52	169.0	COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,2UIQ4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_888643_1	580331.Thit_0129	2.13e-19	86.7	COG0394@1|root,COG0698@1|root,COG0394@2|Bacteria,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,42GC5@68295|Thermoanaerobacterales	186801|Clostridia	G	ribose 5-phosphate isomerase B	ywlF	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LMWPc,LacAB_rpiB
k59_888643_2	1123075.AUDP01000007_gene2771	4.15e-47	159.0	COG0491@1|root,COG0491@2|Bacteria,1TRED@1239|Firmicutes,24P8Q@186801|Clostridia,3WP4A@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_496828_1	639283.Snov_2450	5.48e-05	50.8	COG0030@1|root,COG0030@2|Bacteria,1R4E5@1224|Proteobacteria,2U55D@28211|Alphaproteobacteria,3EZ7M@335928|Xanthobacteraceae	28211|Alphaproteobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
k59_424286_1	395493.BegalDRAFT_1742	4.41e-12	67.8	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,460C6@72273|Thiotrichales	72273|Thiotrichales	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k59_301514_1	1027292.HMPREF9372_1181	2.08e-24	106.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,26F0S@186818|Planococcaceae	91061|Bacilli	M	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHB_HEX_C_1,FlgD_ig,Peptidase_S8,SLH
k59_539332_1	523791.Kkor_0701	2.18e-37	131.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1XJIY@135619|Oceanospirillales	135619|Oceanospirillales	V	Negative regulator of beta-lactamase expression	ampD	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
k59_888663_1	311424.DhcVS_935	1.57e-22	102.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8KS@200795|Chloroflexi,34CTW@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_9
k59_1011538_1	272942.RCAP_rcc02885	3.55e-102	318.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,1FCHB@1060|Rhodobacter	28211|Alphaproteobacteria	C	FAD dependent oxidoreductase central domain	sardh	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k59_770834_1	439235.Dalk_1765	7.4e-41	145.0	COG0287@1|root,COG0287@2|Bacteria,1MVUT@1224|Proteobacteria,42Q2P@68525|delta/epsilon subdivisions,2WMC9@28221|Deltaproteobacteria,2MJU2@213118|Desulfobacterales	28221|Deltaproteobacteria	E	prephenate dehydrogenase	tyrA	-	1.3.1.12,5.4.99.5	ko:K04517,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R01715,R01728	RC00125,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH,PDT
k59_1047118_1	335543.Sfum_1048	1.21e-70	231.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,42PSJ@68525|delta/epsilon subdivisions,2WJDD@28221|Deltaproteobacteria,2MQTR@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
k59_808796_1	1123073.KB899242_gene1468	3.61e-12	72.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,1RZBM@1236|Gammaproteobacteria,1X4YD@135614|Xanthomonadales	135614|Xanthomonadales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_808804_1	1348657.M622_02945	6.28e-63	197.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,2VQZE@28216|Betaproteobacteria,2KW2S@206389|Rhodocyclales	206389|Rhodocyclales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
k59_496873_2	1408418.JNJH01000010_gene3467	8.86e-29	116.0	COG0402@1|root,COG0402@2|Bacteria,1MUFE@1224|Proteobacteria,2TR3A@28211|Alphaproteobacteria,2JPEJ@204441|Rhodospirillales	204441|Rhodospirillales	F	Amidohydrolase family	-	-	3.5.3.13	ko:K05603	ko00340,map00340	-	R02286	RC00682	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_26079_1	9593.ENSGGOP00000017359	2.15e-271	795.0	KOG1833@1|root,KOG1833@2759|Eukaryota,38B5G@33154|Opisthokonta,3BC0G@33208|Metazoa,3CT3Z@33213|Bilateria,48BBW@7711|Chordata,48W6D@7742|Vertebrata,3JFI5@40674|Mammalia,35EMK@314146|Euarchontoglires,4MCU8@9443|Primates,4MXJJ@9604|Hominidae	33208|Metazoa	UY	Bacterial Ig-like domain 2	NUP210	GO:0003674,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005643,GO:0005737,GO:0005783,GO:0005789,GO:0006403,GO:0006405,GO:0006406,GO:0006611,GO:0006810,GO:0006886,GO:0006913,GO:0008104,GO:0008150,GO:0008152,GO:0010467,GO:0012505,GO:0015031,GO:0015833,GO:0015931,GO:0016020,GO:0016032,GO:0017056,GO:0031090,GO:0031503,GO:0031965,GO:0031967,GO:0031975,GO:0031984,GO:0032991,GO:0033036,GO:0034613,GO:0042175,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0046983,GO:0050657,GO:0050658,GO:0051028,GO:0051168,GO:0051169,GO:0051179,GO:0051234,GO:0051236,GO:0051641,GO:0051649,GO:0051704,GO:0070727,GO:0071166,GO:0071426,GO:0071427,GO:0071702,GO:0071704,GO:0071705,GO:0098827	-	ko:K14314	ko03013,map03013	M00427	-	-	ko00000,ko00001,ko00002,ko03019	1.l.1	-	-	Big_2
k59_1245425_1	1121405.dsmv_2935	7.18e-125	364.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,42Q6T@68525|delta/epsilon subdivisions,2WJ4M@28221|Deltaproteobacteria,2MIVF@213118|Desulfobacterales	28221|Deltaproteobacteria	E	HMGL-like	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like
k59_888691_1	443152.MDG893_08050	2.43e-104	312.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,464KF@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed	fadA	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2612,iECNA114_1301.ECNA114_4154,iECOK1_1307.ECOK1_4314,iECP_1309.ECP_4058,iECS88_1305.ECS88_4293,iECSF_1327.ECSF_3702,iEcE24377_1341.EcE24377A_4364,iLF82_1304.LF82_0613,iNRG857_1313.NRG857_19195,iPC815.YPO3767	Thiolase_C,Thiolase_N
k59_340245_1	768671.ThimaDRAFT_1747	1.03e-61	208.0	COG0651@1|root,COG0651@2|Bacteria,1RBAF@1224|Proteobacteria,1S3IZ@1236|Gammaproteobacteria,1X24Y@135613|Chromatiales	135613|Chromatiales	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
k59_182893_1	768066.HELO_3721	6.57e-15	79.3	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1XH98@135619|Oceanospirillales	135619|Oceanospirillales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_539405_1	9606.ENSP00000268379	8.52e-121	355.0	COG0612@1|root,KOG2583@2759|Eukaryota,38EQU@33154|Opisthokonta,3BJNG@33208|Metazoa,3CT6X@33213|Bilateria,48152@7711|Chordata,4971W@7742|Vertebrata,3JB6N@40674|Mammalia,35BJV@314146|Euarchontoglires,4MGM5@9443|Primates,4MVIH@9604|Hominidae	33208|Metazoa	C	Insulinase (Peptidase family M16)	UQCRC2	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005751,GO:0006091,GO:0006119,GO:0006122,GO:0006139,GO:0006163,GO:0006508,GO:0006605,GO:0006626,GO:0006627,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008121,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016485,GO:0016491,GO:0016679,GO:0016681,GO:0016787,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034982,GO:0042773,GO:0042775,GO:0042886,GO:0043167,GO:0043169,GO:0043170,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044877,GO:0045184,GO:0045275,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046907,GO:0046914,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051649,GO:0055086,GO:0055114,GO:0070011,GO:0070013,GO:0070069,GO:0070469,GO:0070585,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072521,GO:0072594,GO:0072655,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0140096,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	-	ko:K00415,ko:K16830	ko00190,ko01100,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04260,map04714,map04932,map05010,map05012,map05016	M00152	-	-	ko00000,ko00001,ko00002,ko01002,ko03036	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_225167_1	713586.KB900536_gene447	5.47e-33	128.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1WWQT@135613|Chromatiales	135613|Chromatiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
k59_967508_2	1117647.M5M_04610	5.11e-49	163.0	COG0811@1|root,COG0811@2|Bacteria,1NXZ9@1224|Proteobacteria,1S154@1236|Gammaproteobacteria,1J4YC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0811 Biopolymer transport proteins	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_967510_1	1415779.JOMH01000001_gene3276	9.86e-18	81.6	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,1X3GV@135614|Xanthomonadales	135614|Xanthomonadales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	cyoE	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
k59_967510_2	1042209.HK44_001785	1.48e-06	51.6	COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SC88@1236|Gammaproteobacteria,1YPG5@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_496923_1	1499967.BAYZ01000048_gene2702	6.73e-93	279.0	COG3752@1|root,COG3752@2|Bacteria,2NR3R@2323|unclassified Bacteria	2|Bacteria	S	3-oxo-5-alpha-steroid 4-dehydrogenase	yfhH	-	1.3.1.22	ko:K12343	ko00140,map00140	-	R02208,R02497,R08954,R10242	RC00145	ko00000,ko00001,ko01000	-	-	-	DUF1295
k59_926681_1	1234364.AMSF01000025_gene3648	1.68e-34	129.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1X3F0@135614|Xanthomonadales	135614|Xanthomonadales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_496944_1	667121.ET1_05_00610	4.24e-77	241.0	COG2204@1|root,COG2204@2|Bacteria,1MWW5@1224|Proteobacteria,1RND4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional activator	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
k59_1123902_1	1196322.A370_04875	0.000487	43.5	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,36E70@31979|Clostridiaceae	186801|Clostridia	C	flavodoxin nitric oxide synthase	norV	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
k59_143579_1	187272.Mlg_1481	2.87e-134	411.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_808915_1	868864.Dester_0394	1.59e-15	86.3	COG1305@1|root,COG1305@2|Bacteria,2G4Q8@200783|Aquificae	200783|Aquificae	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
k59_225223_1	1131730.BAVI_09741	1.22e-71	227.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,1ZB55@1386|Bacillus	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.20	ko:K00270	ko00350,ko00360,ko00400,ko01100,ko01110,ko01130,map00350,map00360,map00400,map01100,map01110,map01130	-	R00688,R09830	RC00006	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_225223_2	903814.ELI_0288	2.71e-27	111.0	COG2006@1|root,COG2006@2|Bacteria,1TRYQ@1239|Firmicutes,24966@186801|Clostridia,25X3Z@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
k59_457539_1	768671.ThimaDRAFT_2039	5.74e-54	187.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1WWQS@135613|Chromatiales	135613|Chromatiales	Q	PFAM Mammalian cell entry related	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_1202520_1	1232437.KL661976_gene4970	1.51e-102	312.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MJ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
k59_225228_1	102129.Lepto7375DRAFT_0663	1.7e-31	126.0	COG3547@1|root,COG3547@2|Bacteria,1G077@1117|Cyanobacteria,1H97S@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_692959_1	1121035.AUCH01000001_gene1785	4.91e-05	48.1	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KUCK@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CZB,EAL,GAF_2,GGDEF,PAS_4,PAS_9
k59_692959_2	1121405.dsmv_1161	3.57e-09	58.2	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,2MIN7@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_808930_1	1294143.H681_09200	8.22e-46	166.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
k59_967557_1	1265505.ATUG01000001_gene4044	4.15e-06	45.1	291H0@1|root,2ZP3M@2|Bacteria,1P8IE@1224|Proteobacteria,432V6@68525|delta/epsilon subdivisions,2WXWA@28221|Deltaproteobacteria,2MP3S@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_496972_1	1267005.KB911258_gene541	1e-106	317.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTI9@28211|Alphaproteobacteria,3N9FJ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
k59_1083841_1	879212.DespoDRAFT_03519	2.16e-21	97.8	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2MIEU@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
k59_808969_1	1410625.JHWK01000004_gene665	1.72e-36	132.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia,27ITP@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	dltR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1123965_1	104623.Ser39006_03755	3.23e-17	82.8	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,1RQ9W@1236|Gammaproteobacteria,402D2@613|Serratia	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,HTH_7,rve
k59_380507_1	1150626.PHAMO_220008	5.09e-16	82.4	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2TS8U@28211|Alphaproteobacteria,2JPQ0@204441|Rhodospirillales	204441|Rhodospirillales	I	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
k59_652895_1	158500.BV97_03648	1.56e-63	207.0	COG3547@1|root,COG3547@2|Bacteria,1Q4TE@1224|Proteobacteria,2TT7C@28211|Alphaproteobacteria,2K2T8@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_888854_1	96561.Dole_2738	1.6e-57	199.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2MHZN@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
k59_262518_1	393595.ABO_2078	2.95e-74	250.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1XHH3@135619|Oceanospirillales	135619|Oceanospirillales	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
k59_967618_1	207559.Dde_0318	2.2e-90	280.0	COG3829@1|root,COG3829@2|Bacteria,1N1WB@1224|Proteobacteria,42P76@68525|delta/epsilon subdivisions,2WIU6@28221|Deltaproteobacteria,2M9BJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
k59_26248_1	330214.NIDE1146	5.88e-82	258.0	COG1249@1|root,COG1249@2|Bacteria,3J0IM@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
k59_183020_1	582744.Msip34_2635	8.99e-59	200.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,2KKSN@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
k59_771049_1	1121405.dsmv_0406	7.61e-65	206.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2MIAE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
k59_771049_2	1121438.JNJA01000004_gene570	8.23e-13	67.4	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2M92B@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_107016_1	177437.HRM2_35890	5e-48	168.0	COG1639@1|root,COG1871@1|root,COG1639@2|Bacteria,COG1871@2|Bacteria,1R5J4@1224|Proteobacteria,42M75@68525|delta/epsilon subdivisions,2WMEB@28221|Deltaproteobacteria,2MISI@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	-	-	-	-	-	-	-	-	-	-	-	-	CheD,HDOD
k59_26286_1	706587.Desti_1833	2.34e-57	193.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42QI1@68525|delta/epsilon subdivisions,2WMJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_26286_2	706587.Desti_1834	1.14e-07	53.1	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,2MQZU@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_1126130_1	439235.Dalk_2721	2.77e-59	194.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2MJ0P@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
k59_1204880_1	593750.Metfor_2059	8.32e-55	181.0	COG0384@1|root,arCOG02256@2157|Archaea,2XUVT@28890|Euryarchaeota	28890|Euryarchaeota	S	Phenazine biosynthesis protein phzf family	phzF	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
k59_577684_1	1121405.dsmv_2231	3.19e-32	115.0	2DNPA@1|root,32YE5@2|Bacteria,1NFYV@1224|Proteobacteria,43C5B@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
k59_577684_2	1401078.HMPREF2140_04470	1.28e-13	71.6	COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,2FMP9@200643|Bacteroidia	976|Bacteroidetes	L	hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
k59_67576_1	1049564.TevJSym_aj00380	1.92e-77	237.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,1J4C3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_970192_1	1121405.dsmv_0889	7.72e-92	274.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NRE@68525|delta/epsilon subdivisions,2WM0E@28221|Deltaproteobacteria,2MJFH@213118|Desulfobacterales	28221|Deltaproteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_970195_1	76869.PputGB1_0627	1.01e-81	257.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,1YVSJ@136845|Pseudomonas putida group	1236|Gammaproteobacteria	I	Belongs to the thiolase family	fadI	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_67597_1	998088.B565_0935	5.52e-40	143.0	COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,1S2HE@1236|Gammaproteobacteria,1Y5BZ@135624|Aeromonadales	135624|Aeromonadales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_773344_1	2340.JV46_05690	1.3e-99	299.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria,1JBRQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG2826 Transposase and inactivated derivatives, IS30 family	insI	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k59_28462_1	1166018.FAES_2975	5.26e-78	249.0	COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,47JJR@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	pcd	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_28462_2	1384056.N787_02590	4.27e-52	175.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1XAD0@135614|Xanthomonadales	135614|Xanthomonadales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
k59_383263_1	1209072.ALBT01000034_gene1783	6.25e-83	259.0	COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1FGKN@10|Cellvibrio	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4478)	ygdH	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464,GO:0047405	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DUF3412,DUF4478,Lysine_decarbox
k59_851492_2	525897.Dbac_0567	8.45e-14	69.3	2E17X@1|root,32WNJ@2|Bacteria,1N3GY@1224|Proteobacteria,42TVS@68525|delta/epsilon subdivisions,2WQQD@28221|Deltaproteobacteria,2MCN4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM cytochrome c class III	tmcA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
k59_342895_1	207954.MED92_05753	1.38e-08	62.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,1XIPZ@135619|Oceanospirillales	135619|Oceanospirillales	S	protein containing LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
k59_1126210_1	1122603.ATVI01000005_gene3516	2.3e-49	176.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,1X3BD@135614|Xanthomonadales	135614|Xanthomonadales	E	Transglutaminase/protease-like homologues	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
k59_303845_1	1408224.SAMCCGM7_c0543	3.23e-48	165.0	COG0717@1|root,COG0717@2|Bacteria,1MVDH@1224|Proteobacteria,2TR5U@28211|Alphaproteobacteria,4B72H@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	2-deoxycytidine 5-triphosphate deaminase	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
k59_67658_1	717785.HYPMC_0548	4.27e-71	228.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2TR64@28211|Alphaproteobacteria,3N6CW@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
k59_459978_1	243233.MCA2191	1.18e-21	98.6	COG1729@1|root,COG1729@2|Bacteria,1MZ7N@1224|Proteobacteria,1T3FY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_145851_1	933262.AXAM01000034_gene1567	5.97e-41	147.0	COG1082@1|root,COG1082@2|Bacteria,1RB9A@1224|Proteobacteria,42QVE@68525|delta/epsilon subdivisions,2WMSP@28221|Deltaproteobacteria,2MJQN@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Xylose	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_1126246_1	391595.RLO149_c011080	9.16e-16	80.9	COG0729@1|root,COG0729@2|Bacteria,1PFDU@1224|Proteobacteria,2VBDR@28211|Alphaproteobacteria,2P4MU@2433|Roseobacter	28211|Alphaproteobacteria	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_521406_2	1121456.ATVA01000014_gene635	2.51e-29	119.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1N4K5@1224|Proteobacteria,42RTP@68525|delta/epsilon subdivisions,2WN9M@28221|Deltaproteobacteria,2M9XH@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_8,Response_reg,SpoIIE
k59_717540_1	666686.B1NLA3E_01380	2.16e-36	132.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,4HD97@91061|Bacilli,1ZC66@1386|Bacillus	91061|Bacilli	G	COG3959 Transketolase, N-terminal subunit	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_717540_2	246194.CHY_0166	2.24e-07	53.5	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,42ET8@68295|Thermoanaerobacterales	186801|Clostridia	G	Transketolase, central region	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_1069346_1	5507.FOXG_08703P0	1.68e-07	60.1	COG1960@1|root,KOG0140@2759|Eukaryota,39TMR@33154|Opisthokonta,3NVT1@4751|Fungi,3QQUV@4890|Ascomycota,217MN@147550|Sordariomycetes,3TKT2@5125|Hypocreales,1FQIE@110618|Nectriaceae	4751|Fungi	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	1.7.3.1	ko:K19823	ko00910,map00910	-	R10388,R10389	RC03154	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N,DASH_Spc34
k59_246993_1	635013.TherJR_2365	5.12e-23	97.1	COG4012@1|root,COG4012@2|Bacteria,1TPF3@1239|Firmicutes,24E9V@186801|Clostridia,260P3@186807|Peptococcaceae	186801|Clostridia	S	pyruvate format-lyase activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
k59_246993_2	177437.HRM2_28110	8.81e-20	87.8	COG2820@1|root,COG2820@2|Bacteria,1QW1B@1224|Proteobacteria,42R3X@68525|delta/epsilon subdivisions,2WP50@28221|Deltaproteobacteria,2MKA8@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM purine or other phosphorylase family 1	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
k59_129282_1	1117318.PRUB_01684	6.77e-72	237.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,2PZF0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_4,DNA_pol3_tau_5
k59_952033_1	153948.NAL212_1923	3.66e-78	237.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2WG5G@28216|Betaproteobacteria,373HV@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
k59_207493_1	670292.JH26_10910	2.49e-62	206.0	COG0160@1|root,COG0160@2|Bacteria,1MX0Y@1224|Proteobacteria,2TRAZ@28211|Alphaproteobacteria,1JWYK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k59_1187394_1	317025.Tcr_2197	1.61e-61	206.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,45ZXV@72273|Thiotrichales	72273|Thiotrichales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
k59_481933_1	1279017.AQYJ01000026_gene57	9.75e-44	163.0	COG1360@1|root,COG2885@1|root,COG1360@2|Bacteria,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,1T4AK@1236|Gammaproteobacteria,46ACU@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA
k59_50855_1	1167006.UWK_02970	2.93e-22	95.9	2AG2Y@1|root,3167D@2|Bacteria,1NN09@1224|Proteobacteria,43EY5@68525|delta/epsilon subdivisions,2X2JQ@28221|Deltaproteobacteria,2MP8Q@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_717593_1	640081.Dsui_0241	5.01e-58	196.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,2KVHS@206389|Rhodocyclales	206389|Rhodocyclales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_912445_1	1163617.SCD_n02382	2.83e-29	114.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2VJNI@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cobyrinic acid ac-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_638681_1	335543.Sfum_2527	3.13e-91	291.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2MQ85@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
k59_1147940_1	686578.AFFX01000006_gene3248	3.75e-75	234.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSSON_1240.SSON_3886,iYL1228.KPN_04138	ATP-synt
k59_11686_3	1121878.AUGL01000007_gene1090	4.12e-247	696.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,1RMHR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2015 Alkyl sulfatase and related hydrolases	BDS1	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
k59_168493_1	1396418.BATQ01000127_gene2553	4.9e-19	91.3	COG0659@1|root,COG2066@1|root,COG0659@2|Bacteria,COG2066@2|Bacteria,46USD@74201|Verrucomicrobia,2ITM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	ET	Glutaminase	-	-	-	-	-	-	-	-	-	-	-	-	Glutaminase,cNMP_binding
k59_325119_1	1122947.FR7_2579	1.53e-07	54.3	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4H1W3@909932|Negativicutes	909932|Negativicutes	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
k59_952140_1	1415779.JOMH01000001_gene657	3.71e-56	188.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,1X31G@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
k59_756094_1	189426.PODO_04895	7.13e-35	134.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,26QT8@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls1	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_1227892_1	572477.Alvin_2090	7.41e-08	57.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1WY2X@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
k59_90946_2	1453501.JELR01000001_gene3098	2.31e-43	153.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RRRW@1236|Gammaproteobacteria,46CEY@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Glutamine synthetase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Gln-synt_C
k59_1109026_1	566466.NOR53_551	1.19e-17	83.6	COG1409@1|root,COG1409@2|Bacteria,1NI34@1224|Proteobacteria,1S397@1236|Gammaproteobacteria,1J9DF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_952170_1	717785.HYPMC_4112	8.89e-34	129.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TR1W@28211|Alphaproteobacteria,3N6IU@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
k59_90965_1	487521.OCU_12400	2.38e-33	129.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,2346K@1762|Mycobacteriaceae	201174|Actinobacteria	L	PFAM Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k59_364920_1	10042.XP_006976141.1	5.95e-146	442.0	KOG0082@1|root,KOG0099@2759|Eukaryota,38C3N@33154|Opisthokonta,3B9MU@33208|Metazoa,3CWC5@33213|Bilateria,485FY@7711|Chordata,48WJQ@7742|Vertebrata,3JC1N@40674|Mammalia,35KMH@314146|Euarchontoglires,4PUYE@9989|Rodentia	33208|Metazoa	T	Guanine nucleotide-binding protein G(s) subunit alpha	GNAS	GO:0000003,GO:0000139,GO:0000166,GO:0001101,GO:0001501,GO:0001503,GO:0001556,GO:0001664,GO:0001726,GO:0001775,GO:0001882,GO:0001883,GO:0001894,GO:0001932,GO:0001934,GO:0001942,GO:0001958,GO:0001965,GO:0002009,GO:0002028,GO:0002165,GO:0002682,GO:0002684,GO:0002761,GO:0002763,GO:0002790,GO:0002791,GO:0003006,GO:0003008,GO:0003013,GO:0003014,GO:0003091,GO:0003674,GO:0003824,GO:0003924,GO:0005102,GO:0005159,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005576,GO:0005604,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005768,GO:0005794,GO:0005802,GO:0005829,GO:0005834,GO:0005886,GO:0006091,GO:0006112,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006355,GO:0006357,GO:0006725,GO:0006807,GO:0006810,GO:0006950,GO:0007154,GO:0007155,GO:0007165,GO:0007186,GO:0007187,GO:0007188,GO:0007189,GO:0007190,GO:0007191,GO:0007212,GO:0007267,GO:0007268,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007444,GO:0007472,GO:0007476,GO:0007528,GO:0007552,GO:0007560,GO:0007565,GO:0007596,GO:0007599,GO:0007600,GO:0007606,GO:0007608,GO:0007610,GO:0007611,GO:0007632,GO:0008015,GO:0008081,GO:0008092,GO:0008104,GO:0008150,GO:0008152,GO:0008217,GO:0008284,GO:0008544,GO:0009306,GO:0009314,GO:0009410,GO:0009416,GO:0009611,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009893,GO:0009898,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0009994,GO:0010033,GO:0010171,GO:0010243,GO:0010353,GO:0010468,GO:0010556,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010648,GO:0010720,GO:0010765,GO:0010817,GO:0010959,GO:0012505,GO:0014070,GO:0015031,GO:0015631,GO:0015833,GO:0015980,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019219,GO:0019220,GO:0019222,GO:0019897,GO:0019898,GO:0019904,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0021700,GO:0022404,GO:0022405,GO:0022412,GO:0022414,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030104,GO:0030154,GO:0030168,GO:0030278,GO:0030326,GO:0030425,GO:0030534,GO:0031012,GO:0031090,GO:0031224,GO:0031234,GO:0031252,GO:0031323,GO:0031325,GO:0031326,GO:0031399,GO:0031401,GO:0031410,GO:0031628,GO:0031681,GO:0031683,GO:0031690,GO:0031698,GO:0031748,GO:0031852,GO:0031982,GO:0031984,GO:0032259,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032588,GO:0032870,GO:0032878,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033036,GO:0033762,GO:0033993,GO:0034109,GO:0034285,GO:0034641,GO:0034694,GO:0034695,GO:0035107,GO:0035108,GO:0035113,GO:0035114,GO:0035116,GO:0035120,GO:0035137,GO:0035220,GO:0035239,GO:0035254,GO:0035255,GO:0035264,GO:0035295,GO:0035556,GO:0035639,GO:0035813,GO:0035814,GO:0036075,GO:0036094,GO:0036477,GO:0040007,GO:0040008,GO:0040014,GO:0040015,GO:0040032,GO:0042060,GO:0042127,GO:0042220,GO:0042221,GO:0042303,GO:0042325,GO:0042327,GO:0042493,GO:0042578,GO:0042592,GO:0042633,GO:0042886,GO:0042995,GO:0043005,GO:0043009,GO:0043014,GO:0043025,GO:0043085,GO:0043087,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043269,GO:0043270,GO:0043279,GO:0043412,GO:0043414,GO:0043434,GO:0043547,GO:0043588,GO:0043900,GO:0043902,GO:0043949,GO:0043950,GO:0044057,GO:0044060,GO:0044062,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044297,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044706,GO:0044728,GO:0044877,GO:0045121,GO:0045184,GO:0045595,GO:0045597,GO:0045637,GO:0045639,GO:0045667,GO:0045669,GO:0045670,GO:0045672,GO:0045776,GO:0045778,GO:0045926,GO:0045937,GO:0046483,GO:0046883,GO:0046903,GO:0046907,GO:0047391,GO:0048148,GO:0048468,GO:0048469,GO:0048471,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048520,GO:0048522,GO:0048523,GO:0048562,GO:0048563,GO:0048568,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048598,GO:0048599,GO:0048609,GO:0048638,GO:0048640,GO:0048646,GO:0048701,GO:0048704,GO:0048705,GO:0048706,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0048871,GO:0048878,GO:0050708,GO:0050780,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050796,GO:0050801,GO:0050808,GO:0050817,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0050909,GO:0050916,GO:0051046,GO:0051048,GO:0051049,GO:0051050,GO:0051051,GO:0051093,GO:0051094,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051336,GO:0051345,GO:0051427,GO:0051428,GO:0051429,GO:0051430,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0055037,GO:0055065,GO:0055074,GO:0055080,GO:0055114,GO:0060173,GO:0060249,GO:0060255,GO:0060259,GO:0060281,GO:0060282,GO:0060284,GO:0060348,GO:0060349,GO:0060350,GO:0060359,GO:0060429,GO:0060562,GO:0060788,GO:0060789,GO:0061448,GO:0062023,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070527,GO:0070542,GO:0070887,GO:0071107,GO:0071229,GO:0071310,GO:0071375,GO:0071377,GO:0071379,GO:0071380,GO:0071396,GO:0071398,GO:0071407,GO:0071417,GO:0071495,GO:0071514,GO:0071695,GO:0071696,GO:0071697,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071855,GO:0071867,GO:0071868,GO:0071869,GO:0071870,GO:0071875,GO:0071880,GO:0071944,GO:0072347,GO:0072507,GO:0080090,GO:0090036,GO:0090038,GO:0090087,GO:0090276,GO:0090304,GO:0097159,GO:0097305,GO:0097306,GO:0097367,GO:0097447,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098589,GO:0098609,GO:0098771,GO:0098773,GO:0098791,GO:0098796,GO:0098797,GO:0098801,GO:0098805,GO:0098857,GO:0098916,GO:0099536,GO:0099537,GO:0120025,GO:0120038,GO:1900193,GO:1900195,GO:1901265,GO:1901360,GO:1901363,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902105,GO:1902107,GO:1902494,GO:1902531,GO:1902532,GO:1902533,GO:1903429,GO:1903431,GO:1903506,GO:1903530,GO:1903706,GO:1903708,GO:1904888,GO:1905360,GO:1905879,GO:1905881,GO:2000026,GO:2000112,GO:2000114,GO:2000241,GO:2000243,GO:2000253,GO:2000292,GO:2000828,GO:2001141	-	ko:K04632	ko01522,ko04015,ko04020,ko04024,ko04072,ko04261,ko04270,ko04540,ko04611,ko04713,ko04714,ko04724,ko04726,ko04728,ko04730,ko04750,ko04911,ko04912,ko04913,ko04915,ko04916,ko04918,ko04921,ko04922,ko04923,ko04924,ko04925,ko04926,ko04927,ko04934,ko04961,ko04962,ko04970,ko04971,ko04972,ko04976,ko05030,ko05031,ko05032,ko05034,ko05110,ko05142,ko05146,ko05165,ko05200,ko05414,map01522,map04015,map04020,map04024,map04072,map04261,map04270,map04540,map04611,map04713,map04714,map04724,map04726,map04728,map04730,map04750,map04911,map04912,map04913,map04915,map04916,map04918,map04921,map04922,map04923,map04924,map04925,map04926,map04927,map04934,map04961,map04962,map04970,map04971,map04972,map04976,map05030,map05031,map05032,map05034,map05110,map05142,map05146,map05165,map05200,map05414	M00695	-	-	ko00000,ko00001,ko00002,ko04031,ko04147	-	-	-	G-alpha
k59_1069487_1	1123247.AUIJ01000003_gene1986	4.37e-148	434.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1148011_1	298655.KI912266_gene2677	1.06e-13	75.1	COG0599@1|root,COG0599@2|Bacteria,2HCR9@201174|Actinobacteria,4EU0P@85013|Frankiales	201174|Actinobacteria	S	PFAM Carboxymuconolactone decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
k59_834565_1	517418.Ctha_1507	7.57e-15	73.6	COG0031@1|root,COG0031@2|Bacteria,1FD8M@1090|Chlorobi	1090|Chlorobi	H	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_442864_1	1331060.RLDS_11275	7.34e-40	138.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,2KCX1@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the GST superfamily	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_N,GST_N_3
k59_404629_1	1506583.JQJY01000006_gene4408	8.04e-65	223.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1HX2H@117743|Flavobacteriia,2NTDQ@237|Flavobacterium	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_993035_2	1453501.JELR01000002_gene992	6.78e-24	101.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,4644I@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
k59_1032514_1	662479.C440_07312	6.33e-10	65.5	COG0471@1|root,arCOG00237@2157|Archaea,2XSW7@28890|Euryarchaeota,23SDG@183963|Halobacteria	183963|Halobacteria	P	COG0471 Di- and tricarboxylate transporters	arsB	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_404647_2	1209984.BN978_02620	3.82e-18	88.6	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,2370G@1762|Mycobacteriaceae	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_560348_1	84531.JMTZ01000022_gene4194	1.86e-73	233.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1X4R7@135614|Xanthomonadales	135614|Xanthomonadales	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
k59_404670_1	1122603.ATVI01000005_gene3501	3.84e-35	140.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SZ6C@1236|Gammaproteobacteria,1XCCV@135614|Xanthomonadales	1236|Gammaproteobacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_19,TPR_2,TPR_8
k59_677988_1	1121440.AUMA01000001_gene88	2.32e-58	201.0	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,42NWX@68525|delta/epsilon subdivisions,2WIZY@28221|Deltaproteobacteria,2M9QV@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
k59_129475_2	1071679.BG57_24865	1.6e-93	282.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,1JZVF@119060|Burkholderiaceae	28216|Betaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_1032560_1	9593.ENSGGOP00000004850	6.91e-106	310.0	COG1100@1|root,KOG0075@2759|Eukaryota,38F0Z@33154|Opisthokonta,3BGPU@33208|Metazoa,3CSE4@33213|Bilateria,47ZTY@7711|Chordata,48VJX@7742|Vertebrata,3JCW5@40674|Mammalia,35CX5@314146|Euarchontoglires,4MM2K@9443|Primates,4MV49@9604|Hominidae	33208|Metazoa	U	May play a role in lysosome motility. May play a role in chromosome segregation	ARL8B	GO:0000166,GO:0000306,GO:0000323,GO:0000819,GO:0001666,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005765,GO:0005773,GO:0005774,GO:0005819,GO:0005856,GO:0006810,GO:0006928,GO:0006950,GO:0006996,GO:0007017,GO:0007018,GO:0007034,GO:0007041,GO:0007049,GO:0007059,GO:0008088,GO:0008092,GO:0008150,GO:0008333,GO:0009628,GO:0009987,GO:0010970,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016192,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019898,GO:0022402,GO:0030496,GO:0030705,GO:0031090,GO:0031312,GO:0032418,GO:0032419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036293,GO:0043014,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044437,GO:0044444,GO:0044446,GO:0044456,GO:0044464,GO:0045202,GO:0046907,GO:0048487,GO:0048786,GO:0050896,GO:0051179,GO:0051233,GO:0051234,GO:0051276,GO:0051640,GO:0051641,GO:0051649,GO:0070482,GO:0071840,GO:0097159,GO:0097367,GO:0097458,GO:0098588,GO:0098793,GO:0098805,GO:0098813,GO:0098852,GO:0099111,GO:1901265,GO:1901363	-	ko:K07955	-	-	-	-	ko00000,ko04031,ko04131	-	-	-	Arf
k59_717755_2	1150626.PHAMO_80060	8.87e-25	114.0	COG1061@1|root,COG1061@2|Bacteria	2|Bacteria	L	Type III restriction enzyme res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k59_51009_1	160488.PP_0741	3.62e-41	146.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,1RNMF@1236|Gammaproteobacteria,1YV9E@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1722)	ybgA	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
k59_51009_2	493475.GARC_2258	0.000179	43.5	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RPDW@1236|Gammaproteobacteria,466J8@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2200 FOG EAL domain	ycgF	-	-	ko:K21973	-	-	-	-	ko00000	-	-	-	EAL
k59_404698_1	396588.Tgr7_2759	3.28e-108	323.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1WWZ0@135613|Chromatiales	135613|Chromatiales	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_51019_1	380358.XALC_1971	3.75e-15	77.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0C@1236|Gammaproteobacteria,1X3N0@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k59_51019_2	1217703.F904_01562	1.73e-18	85.5	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,3NIFA@468|Moraxellaceae	1236|Gammaproteobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_952263_1	1158292.JPOE01000002_gene2953	5.11e-90	286.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_91055_1	566466.NOR53_696	2e-55	194.0	COG3544@1|root,COG3544@2|Bacteria,1N0KY@1224|Proteobacteria,1SBTF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
k59_1148100_1	30611.ENSOGAP00000008041	1.12e-64	211.0	COG0459@1|root,KOG0364@2759|Eukaryota,38GPW@33154|Opisthokonta,3BFX2@33208|Metazoa,3CYB8@33213|Bilateria,47ZAK@7711|Chordata,48XID@7742|Vertebrata,3JCEM@40674|Mammalia,35IMN@314146|Euarchontoglires,4MFBM@9443|Primates	33208|Metazoa	O	unfolded protein binding	CCT3	GO:0000003,GO:0002199,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005832,GO:0005856,GO:0005874,GO:0005886,GO:0006457,GO:0006458,GO:0006810,GO:0007338,GO:0007339,GO:0008037,GO:0008150,GO:0009566,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009988,GO:0010556,GO:0010557,GO:0010604,GO:0010638,GO:0015630,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019953,GO:0022414,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031647,GO:0032204,GO:0032206,GO:0032210,GO:0032212,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033044,GO:0035036,GO:0042623,GO:0043209,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044183,GO:0044297,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044703,GO:0045935,GO:0046931,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050821,GO:0051052,GO:0051054,GO:0051082,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051704,GO:0060255,GO:0060341,GO:0061077,GO:0065003,GO:0065007,GO:0065008,GO:0070201,GO:0070202,GO:0070203,GO:0071840,GO:0071944,GO:0080090,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0101031,GO:1901998,GO:1903827,GO:1903829,GO:1904356,GO:1904358,GO:1904814,GO:1904816,GO:1904851,GO:1904951,GO:2000112,GO:2000278,GO:2000573,GO:2001252	-	ko:K09495	-	-	-	-	ko00000,ko03036,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_1109138_1	882.DVU_0681	3.39e-07	59.3	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg
k59_404746_1	1357275.AVEL02000151_gene1536	7.76e-62	203.0	COG0863@1|root,COG0863@2|Bacteria,1MY4G@1224|Proteobacteria,1RQHA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
k59_795246_2	795359.TOPB45_0621	1.77e-18	84.3	COG0499@1|root,COG0499@2|Bacteria,2GGXJ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_756224_1	1163408.UU9_06169	7.52e-32	125.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,1X5V3@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1228096_1	880072.Desac_0948	7.34e-32	124.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,43AFG@68525|delta/epsilon subdivisions,2WKA9@28221|Deltaproteobacteria,2MQMK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PFAM glycosyl transferase, family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_1150355_1	745411.B3C1_12579	1.96e-24	97.4	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1J50E@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_93427_1	1510531.JQJJ01000010_gene2444	9.83e-17	79.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,3JU27@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	ABC transporter	hndI	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_93427_2	420662.Mpe_A0977	1.75e-113	332.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2VJMJ@28216|Betaproteobacteria,1KJZY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	ABC-2 type transporter	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
k59_876110_1	477974.Daud_1180	0.00098	42.7	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,261QH@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k59_876110_2	762983.HMPREF9444_00563	9.17e-13	68.6	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1Y3HM@135624|Aeromonadales	135624|Aeromonadales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_93451_1	9402.XP_006923313.1	2.51e-72	231.0	KOG4211@1|root,KOG4211@2759|Eukaryota,38B9D@33154|Opisthokonta,3BBKX@33208|Metazoa,3CRF2@33213|Bilateria,47ZD1@7711|Chordata,48WB3@7742|Vertebrata,3J4ZW@40674|Mammalia,4M3SS@9397|Chiroptera	33208|Metazoa	A	RNPHF zinc finger	HNRNPH1	GO:0000003,GO:0000375,GO:0000377,GO:0000398,GO:0000578,GO:0003002,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003729,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006397,GO:0006403,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0007028,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007310,GO:0007311,GO:0007314,GO:0007315,GO:0007316,GO:0007350,GO:0007351,GO:0007389,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0008298,GO:0008358,GO:0008380,GO:0008543,GO:0008595,GO:0009611,GO:0009719,GO:0009790,GO:0009798,GO:0009880,GO:0009889,GO:0009948,GO:0009950,GO:0009952,GO:0009953,GO:0009987,GO:0009994,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016070,GO:0016071,GO:0019094,GO:0019219,GO:0019222,GO:0019899,GO:0019953,GO:0021700,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030154,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033036,GO:0034248,GO:0034641,GO:0035282,GO:0042060,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043484,GO:0044085,GO:0044237,GO:0044238,GO:0044344,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045451,GO:0046483,GO:0048468,GO:0048469,GO:0048477,GO:0048599,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051179,GO:0051246,GO:0051252,GO:0051276,GO:0051641,GO:0051704,GO:0051716,GO:0060255,GO:0060810,GO:0060811,GO:0065007,GO:0070013,GO:0070727,GO:0070848,GO:0070887,GO:0071013,GO:0071310,GO:0071363,GO:0071417,GO:0071495,GO:0071704,GO:0071774,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1990904,GO:2000112	-	ko:K12898	-	-	-	-	ko00000,ko03041	-	-	-	RRM_1,zf-RNPHF
k59_249544_1	28737.XP_006883122.1	3.89e-120	343.0	KOG3318@1|root,KOG3318@2759|Eukaryota,3A6CP@33154|Opisthokonta,3BHEG@33208|Metazoa,3D3W5@33213|Bilateria,48AFC@7711|Chordata,48XT9@7742|Vertebrata,3J9TN@40674|Mammalia,34U7Z@311790|Afrotheria	33208|Metazoa	S	ER membrane protein complex subunit 4	EMC4	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006457,GO:0008150,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0032991,GO:0034975,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0072546,GO:0098796,GO:0098827	-	-	-	-	-	-	-	-	-	-	DUF1077
k59_170900_1	439235.Dalk_3619	7.07e-130	379.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42PRI@68525|delta/epsilon subdivisions,2X5GA@28221|Deltaproteobacteria,2MHVA@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_1150382_1	863365.XHC_4346	7.01e-100	294.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1X3YF@135614|Xanthomonadales	135614|Xanthomonadales	F	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k59_1150382_2	342610.Patl_3429	7.72e-14	72.4	COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,1RMQK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	gluconolactonase	-	-	-	-	-	-	-	-	-	-	-	-	SGL,Str_synth
k59_93458_1	768671.ThimaDRAFT_3441	5.07e-71	224.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,1S2GK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
k59_1231208_2	990285.RGCCGE502_22320	7.03e-46	166.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TTBA@28211|Alphaproteobacteria,4BAZE@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_996317_1	1123354.AUDR01000015_gene434	1.02e-37	137.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria,1KS39@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
k59_1189915_1	266835.14027537	1.01e-63	211.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,43HY4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_14164_1	96561.Dole_0627	1.49e-40	143.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,2MKD4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
k59_249622_1	1208323.B30_14029	9.06e-28	117.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	poly-beta-hydroxybutyrate polymerase	-	-	-	-	-	-	-	-	-	-	-	-	PHBC_N,PhaC_N
k59_954714_1	34506.g743	4.67e-37	138.0	2BXVV@1|root,2S2FZ@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP,GSH-S_N,Lactamase_B
k59_693912_1	465817.ETA_27950	2.12e-31	120.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMMZ@1236|Gammaproteobacteria,3X63F@551|Erwinia	1236|Gammaproteobacteria	IQ	KR domain	ygfF	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_1012448_1	311402.Avi_2710	3.21e-05	48.5	COG3383@1|root,COG3383@2|Bacteria,1QUPZ@1224|Proteobacteria,2TWJY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4
k59_1012448_2	243231.GSU2792	1.68e-82	254.0	COG0500@1|root,COG0500@2|Bacteria,1QW0F@1224|Proteobacteria,43C56@68525|delta/epsilon subdivisions,2X7FJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_616075_1	1415778.JQMM01000001_gene1140	3.99e-86	277.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVS@1236|Gammaproteobacteria,1J55S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA
k59_381696_1	883080.HMPREF9697_01326	1.04e-37	135.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TU4V@28211|Alphaproteobacteria,3JRS0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.1.1.41,4.2.1.17	ko:K01692,ko:K11264	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R00923,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00097,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_1124909_1	292415.Tbd_0253	3.02e-48	170.0	COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,2WGXV@28216|Betaproteobacteria,1KSDH@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
k59_302587_1	716928.AJQT01000037_gene735	4.5e-10	63.2	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,1Q823@1224|Proteobacteria,2TV64@28211|Alphaproteobacteria,4B7EE@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
k59_302587_2	1121106.JQKB01000016_gene5325	4.17e-07	51.2	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_927644_1	1122970.AUHC01000013_gene1074	7.78e-45	149.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,2U78G@28211|Alphaproteobacteria,2K4FM@204457|Sphingomonadales	204457|Sphingomonadales	S	dioxygenase of extradiol dioxygenase family	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
k59_927644_2	1336233.JAEH01000038_gene4200	3.44e-10	59.7	COG3788@1|root,COG3788@2|Bacteria,1RDHP@1224|Proteobacteria,1S3PN@1236|Gammaproteobacteria,2QC72@267890|Shewanellaceae	1236|Gammaproteobacteria	S	MAPEG family	-	-	-	ko:K07136	-	-	-	-	ko00000	-	-	-	MAPEG
k59_66154_1	717605.Theco_2526	7.68e-31	120.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli,26TK1@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_927646_1	933262.AXAM01000001_gene347	1.22e-44	159.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2MHZW@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
k59_927646_2	335543.Sfum_4045	2.44e-39	132.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,42SN5@68525|delta/epsilon subdivisions,2WP28@28221|Deltaproteobacteria,2MS1Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	DsrC like protein	dsrC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
k59_1124929_1	338963.Pcar_1181	9.12e-41	153.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1PFBZ@1224|Proteobacteria,439XJ@68525|delta/epsilon subdivisions,2X1UU@28221|Deltaproteobacteria,43VBR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
k59_1084754_1	272123.Anacy_1360	3e-61	208.0	COG2304@1|root,COG2304@2|Bacteria,1G3PE@1117|Cyanobacteria,1HKB6@1161|Nostocales	1117|Cyanobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
k59_183752_1	667014.Thein_0251	1.18e-80	251.0	COG0683@1|root,COG0683@2|Bacteria,2GI8J@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_497940_1	930169.B5T_03494	6.95e-99	308.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1XHBX@135619|Oceanospirillales	135619|Oceanospirillales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
k59_576070_1	314285.KT71_12625	1.45e-20	90.9	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RY52@1236|Gammaproteobacteria,1J7GW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_497956_1	1267535.KB906767_gene2749	7.25e-50	167.0	COG3620@1|root,COG3620@2|Bacteria,3Y6X6@57723|Acidobacteria	57723|Acidobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
k59_1012496_1	1120792.JAFV01000001_gene233	1.14e-06	51.6	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2TQRE@28211|Alphaproteobacteria,371J0@31993|Methylocystaceae	28211|Alphaproteobacteria	T	HAMP domain	envZ	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_1012496_2	670307.HYPDE_36098	6.62e-44	149.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TSQF@28211|Alphaproteobacteria,3N7ZT@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	Two component transcriptional regulator	petR	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_693975_1	1532557.JL37_24525	3.08e-21	90.1	2C852@1|root,32YB2@2|Bacteria,1RH28@1224|Proteobacteria,2VSQ3@28216|Betaproteobacteria,3T6ZC@506|Alcaligenaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
k59_108198_1	1479235.KK366039_gene445	3.87e-72	239.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1XN4U@135619|Oceanospirillales	135619|Oceanospirillales	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	-	-	-	ko:K05565	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,Proton_antipo_M,Proton_antipo_N
k59_226175_1	1121405.dsmv_1716	3.08e-34	119.0	2EEQW@1|root,338IK@2|Bacteria,1NCXT@1224|Proteobacteria,42VG4@68525|delta/epsilon subdivisions,2WR9K@28221|Deltaproteobacteria,2MKU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
k59_576079_1	504728.K649_13075	1.22e-40	144.0	COG1028@1|root,COG1028@2|Bacteria,1WJW2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_771989_2	1265505.ATUG01000003_gene517	4.74e-54	172.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria,2MN9A@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_771989_3	1232437.KL662050_gene5292	3.75e-21	86.7	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
k59_302637_1	316056.RPC_4749	2.98e-51	171.0	COG3916@1|root,COG3916@2|Bacteria,1R6MX@1224|Proteobacteria,2TR6Y@28211|Alphaproteobacteria,3JT6K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	QT	Acyl-homoserine-lactone synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1163984_1	1159870.KB907784_gene751	1.78e-34	127.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2VI3W@28216|Betaproteobacteria,3T1Z2@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_381791_1	1265505.ATUG01000001_gene4189	8.98e-87	269.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,42PC8@68525|delta/epsilon subdivisions,2X5FY@28221|Deltaproteobacteria,2MQ3C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_381804_1	317655.Sala_0533	3.27e-46	164.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2TRZV@28211|Alphaproteobacteria,2K46G@204457|Sphingomonadales	204457|Sphingomonadales	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
k59_1203618_1	1089550.ATTH01000001_gene2120	2.39e-23	106.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1FIWT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Pyruvate:ferredoxin oxidoreductase core domain II	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_497993_1	1429851.X548_07230	4.09e-138	405.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1X2YI@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
k59_889843_1	1232437.KL662010_gene1605	1.49e-89	278.0	COG0034@1|root,COG0034@2|Bacteria,1R7JX@1224|Proteobacteria,42MAC@68525|delta/epsilon subdivisions,2WKFD@28221|Deltaproteobacteria,2MIUW@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Glutamine amidotransferase domain	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
k59_616214_1	335543.Sfum_0687	2.78e-11	68.9	COG1413@1|root,COG1413@2|Bacteria,1P1H4@1224|Proteobacteria,431VX@68525|delta/epsilon subdivisions,2WWU3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1012534_1	1121405.dsmv_0342	4.55e-84	263.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_381837_1	543913.D521_1232	8.13e-10	58.5	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2VHD7@28216|Betaproteobacteria,1KQ6F@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	PFAM 20S proteasome, A and B subunits	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
k59_341447_1	644282.Deba_2226	2.38e-81	271.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
k59_183821_1	626887.J057_03185	5.36e-69	219.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,464IK@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_968891_1	883080.HMPREF9697_03471	2.83e-48	160.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,2U5BS@28211|Alphaproteobacteria,3JREZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	DJ-1/PfpI family	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
k59_1248424_1	153948.NAL212_2601	2.75e-39	137.0	COG1943@1|root,COG1943@2|Bacteria,1QKQ2@1224|Proteobacteria,2WC8F@28216|Betaproteobacteria,374G1@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
k59_618473_2	1122611.KB904018_gene7053	4.15e-08	55.1	COG0520@1|root,COG0520@2|Bacteria,2GKAF@201174|Actinobacteria,4EGB0@85012|Streptosporangiales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_930347_1	1283300.ATXB01000001_gene660	5.43e-141	408.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1XDX9@135618|Methylococcales	135618|Methylococcales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
k59_852618_1	441768.ACL_0821	6.01e-13	67.4	COG2131@1|root,COG2131@2|Bacteria,3WTJG@544448|Tenericutes	544448|Tenericutes	F	Deoxycytidylate deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k59_428709_1	661367.LLO_0290	8.48e-19	87.8	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,1JCBH@118969|Legionellales	118969|Legionellales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_656252_1	247633.GP2143_15446	2.86e-07	52.4	COG3312@1|root,COG3312@2|Bacteria,1QJ6N@1224|Proteobacteria,1TH49@1236|Gammaproteobacteria,1J72W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG3312 F0F1-type ATP synthase, subunit I	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
k59_656252_2	1117315.AHCA01000021_gene4284	4.14e-09	57.8	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,2Q1CH@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
k59_774604_1	399739.Pmen_3490	2.05e-12	67.4	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1YDXF@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
k59_774604_2	1116472.MGMO_83c00160	5.88e-62	206.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1XESH@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
k59_892281_1	1125863.JAFN01000001_gene673	2.53e-65	213.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_852685_1	933262.AXAM01000022_gene3228	1.82e-94	292.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2MHVD@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
k59_186007_1	1232437.KL662011_gene1449	1.93e-63	199.0	COG0484@1|root,COG0484@2|Bacteria,1RHHJ@1224|Proteobacteria,42SMN@68525|delta/epsilon subdivisions,2WPJN@28221|Deltaproteobacteria,2MNCE@213118|Desulfobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
k59_111088_1	331869.BAL199_24884	3.01e-52	179.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRGU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	BQ	Including yeast histone deacetylase and acetoin utilization protein	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
k59_1014732_1	313606.M23134_02646	6.13e-19	90.1	COG0501@1|root,COG0501@2|Bacteria,4PKND@976|Bacteroidetes,47XXF@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the peptidase M48B family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_930459_1	643562.Daes_0583	1.03e-10	70.1	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PTW@68525|delta/epsilon subdivisions,2WK32@28221|Deltaproteobacteria,2MHHJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
k59_892319_1	1121875.KB907550_gene638	2.89e-24	102.0	COG5361@1|root,COG5361@2|Bacteria,4NKSK@976|Bacteroidetes,1IARY@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_1206225_2	706587.Desti_3137	3.25e-26	111.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2MQ5N@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
k59_1248556_2	537970.HCAN_0994	8.09e-19	89.7	COG1145@1|root,COG1145@2|Bacteria,1MWHY@1224|Proteobacteria,42MHE@68525|delta/epsilon subdivisions,2YMW8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_7,Fer4_9
k59_111128_1	1121405.dsmv_1099	5.21e-120	350.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2WK5N@28221|Deltaproteobacteria,2MMZ0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K00167	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
k59_618675_1	756272.Plabr_3458	9.95e-41	154.0	COG0370@1|root,COG0370@2|Bacteria,2IYCI@203682|Planctomycetes	203682|Planctomycetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
k59_305031_1	1453501.JELR01000002_gene1024	4.69e-103	307.0	COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,1RNYV@1236|Gammaproteobacteria,465V2@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	uptA	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
k59_971662_1	998674.ATTE01000001_gene1573	4.16e-94	288.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,1RPPD@1236|Gammaproteobacteria,461TK@72273|Thiotrichales	72273|Thiotrichales	E	Peptidase family M28	-	-	3.5.3.9	ko:K02083	ko00230,ko01120,map00230,map01120	-	R02423	RC00064	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_696458_2	314265.R2601_18608	7.72e-08	54.7	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TUKX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
k59_579094_1	643562.Daes_0684	9.56e-49	174.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PDY@68525|delta/epsilon subdivisions,2WMD0@28221|Deltaproteobacteria,2M7R7@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
k59_971666_1	933262.AXAM01000013_gene1292	2.44e-106	317.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2MHV9@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_696463_1	1033802.SSPSH_002108	4.56e-38	141.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	acetolactate synthase	ilvI	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_696463_2	626887.J057_05581	1.12e-43	150.0	COG4221@1|root,COG4221@2|Bacteria,1QWIS@1224|Proteobacteria,1T38Y@1236|Gammaproteobacteria,467A0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_819831_2	870187.Thini_3341	1.35e-21	92.8	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,4604K@72273|Thiotrichales	72273|Thiotrichales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
k59_900151_1	1265505.ATUG01000002_gene1666	2.26e-63	213.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,1MU0N@1224|Proteobacteria,43BK2@68525|delta/epsilon subdivisions,2X6XX@28221|Deltaproteobacteria,2MPNK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Response regulator receiver domain	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,PAS_4,PAS_9,Response_reg,Sigma54_activat
k59_312434_1	391587.KAOT1_05747	2.37e-07	54.7	COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,MAM,Peptidase_M14,Peptidase_M43,Reprolysin_4,fn3
k59_508100_1	335283.Neut_2145	4.36e-08	57.4	COG1397@1|root,COG1397@2|Bacteria,1MXJP@1224|Proteobacteria,2VNAC@28216|Betaproteobacteria,371QQ@32003|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
k59_508100_3	526224.Bmur_1332	6.4e-07	50.8	2C2JW@1|root,3316C@2|Bacteria	2|Bacteria	S	Domain of Unknown Function (DUF1599)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1599
k59_508100_4	509635.N824_21220	9.65e-18	84.0	COG0338@1|root,COG0338@2|Bacteria,4NFZ2@976|Bacteroidetes,1IUQP@117747|Sphingobacteriia	976|Bacteroidetes	L	D12 class N6 adenine-specific DNA methyltransferase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
k59_819850_1	1232437.KL662010_gene1616	1.36e-85	261.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,42QQQ@68525|delta/epsilon subdivisions,2WMBP@28221|Deltaproteobacteria,2MIM7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
k59_819854_1	482537.XP_008589814.1	6.81e-133	379.0	COG2092@1|root,KOG1668@2759|Eukaryota,38BNW@33154|Opisthokonta,3BGBS@33208|Metazoa,3CXWZ@33213|Bilateria,480S8@7711|Chordata,48XBK@7742|Vertebrata,3J5RS@40674|Mammalia,35J7W@314146|Euarchontoglires	33208|Metazoa	J	translation elongation factor activity	EEF1B2	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005853,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009636,GO:0009987,GO:0010033,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042221,GO:0042493,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045471,GO:0046677,GO:0050896,GO:0071704,GO:0097159,GO:0097305,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901700	-	ko:K03232,ko:K15410	ko05168,map05168	-	-	-	ko00000,ko00001,ko03012	-	-	-	EF-1_beta_acid,EF1_GNE
k59_75820_1	159087.Daro_1171	5.05e-06	54.3	COG3713@1|root,COG3713@2|Bacteria,1MWQN@1224|Proteobacteria,2VX3J@28216|Betaproteobacteria,2KZGI@206389|Rhodocyclales	206389|Rhodocyclales	M	MltA-interacting protein MipA	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	MipA
k59_979485_2	379066.GAU_0394	4.17e-07	51.2	COG0591@1|root,COG0591@2|Bacteria,1ZT93@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_351768_1	1550091.JROE01000002_gene1062	5.5e-38	145.0	COG0587@1|root,COG0587@2|Bacteria,4NGTT@976|Bacteroidetes,1IQQT@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_979503_1	9598.ENSPTRP00000022905	1.74e-60	204.0	28P45@1|root,2QVQS@2759|Eukaryota,38E0C@33154|Opisthokonta,3BF83@33208|Metazoa,3D056@33213|Bilateria,4856R@7711|Chordata,4944D@7742|Vertebrata,3JAVD@40674|Mammalia,35MTS@314146|Euarchontoglires,4MB7Y@9443|Primates,4MTJR@9604|Hominidae	33208|Metazoa	Z	importin-alpha family protein binding	TPX2	GO:0000166,GO:0000226,GO:0000278,GO:0000280,GO:0001882,GO:0001883,GO:0001932,GO:0001934,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005815,GO:0005818,GO:0005819,GO:0005829,GO:0005856,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007346,GO:0008144,GO:0008150,GO:0008283,GO:0009893,GO:0009966,GO:0009987,GO:0010389,GO:0010562,GO:0010564,GO:0010604,GO:0010646,GO:0015630,GO:0016043,GO:0017076,GO:0019001,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022402,GO:0022607,GO:0023051,GO:0030424,GO:0030554,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032147,GO:0032268,GO:0032270,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032886,GO:0033043,GO:0033267,GO:0033674,GO:0035639,GO:0036094,GO:0036477,GO:0042325,GO:0042327,GO:0042995,GO:0043005,GO:0043025,GO:0043085,GO:0043167,GO:0043168,GO:0043203,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0044085,GO:0044093,GO:0044297,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0045171,GO:0045859,GO:0045860,GO:0045937,GO:0048285,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051171,GO:0051173,GO:0051174,GO:0051225,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0051493,GO:0051726,GO:0060236,GO:0060255,GO:0061676,GO:0065007,GO:0065009,GO:0070013,GO:0070507,GO:0070925,GO:0071840,GO:0072686,GO:0080090,GO:0090224,GO:0090307,GO:0097159,GO:0097367,GO:0097458,GO:0099080,GO:0120025,GO:0120038,GO:0140014,GO:1901265,GO:1901363,GO:1901796,GO:1901987,GO:1901990,GO:1902531,GO:1902749,GO:1902850,GO:1903047	-	ko:K16812	-	-	-	-	ko00000,ko03036	-	-	-	Aurora-A_bind,TPX2,TPX2_importin
k59_273629_1	1453501.JELR01000002_gene1229	1.3e-43	155.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,464N0@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
k59_937947_1	1304885.AUEY01000041_gene3681	7.93e-12	67.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2WIWY@28221|Deltaproteobacteria,2MHR1@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_273659_2	696281.Desru_0556	4.61e-29	115.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,2611T@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gluD	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_1213832_1	1255043.TVNIR_2583	1.92e-33	120.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1WXDE@135613|Chromatiales	135613|Chromatiales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_37336_1	640510.BC1001_0191	1.09e-106	322.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1JZW5@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_1095033_1	1317124.DW2_09441	9.89e-20	83.2	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2U71N@28211|Alphaproteobacteria,2XN9M@285107|Thioclava	28211|Alphaproteobacteria	S	EVE domain	MA20_25125	-	-	-	-	-	-	-	-	-	-	-	EVE
k59_1095033_2	639283.Snov_2811	2.7e-40	140.0	COG3897@1|root,COG3897@2|Bacteria,1N9VC@1224|Proteobacteria,2TV6N@28211|Alphaproteobacteria,3EYVW@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Lysine methyltransferase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736	-	-	-	-	-	-	-	-	-	-	PrmA
k59_154423_1	323848.Nmul_A1444	2.96e-24	106.0	291GM@1|root,2ZP3A@2|Bacteria,1RD1E@1224|Proteobacteria,2VRS0@28216|Betaproteobacteria,372PP@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_75952_1	335543.Sfum_0122	1.13e-126	388.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2MQ7V@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_1134903_1	701347.Entcl_2514	1.32e-12	72.8	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,3X1BN@547|Enterobacter	1236|Gammaproteobacteria	K	Transcriptional regulator	cysB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_37385_1	439235.Dalk_0385	2.93e-46	161.0	COG1148@1|root,COG1148@2|Bacteria,1R9EV@1224|Proteobacteria,42PIR@68525|delta/epsilon subdivisions,2WK4U@28221|Deltaproteobacteria	2|Bacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885,ko:K16886	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
k59_154477_1	744979.R2A130_1742	7.15e-19	91.3	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,2TXWU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	COG2771 DNA-binding HTH domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GerE
k59_1174637_1	1286171.EAL2_c10400	8.04e-48	171.0	COG0275@1|root,COG0682@1|root,COG0275@2|Bacteria,COG0682@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,25UQQ@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_351900_1	1415779.JOMH01000001_gene181	2.27e-09	63.5	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA
k59_508259_2	28258.KP05_06805	2.18e-27	114.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1XIR3@135619|Oceanospirillales	135619|Oceanospirillales	H	biosynthesis protein HemY	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_7
k59_743164_1	745411.B3C1_07726	1.88e-31	129.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J5MB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CZB,DUF4118,EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Protoglobin
k59_273783_1	1499967.BAYZ01000041_gene2386	6.9e-85	263.0	COG1593@1|root,COG1593@2|Bacteria,2NQTB@2323|unclassified Bacteria	2|Bacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_1134970_1	566466.NOR53_491	3.68e-33	132.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_8,Trans_reg_C
k59_273803_1	296591.Bpro_3024	0.000372	42.4	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VM40@28216|Betaproteobacteria,4AC98@80864|Comamonadaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
k59_273803_2	1122614.JHZF01000011_gene1667	1.96e-58	193.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2PDV4@252301|Oceanicola	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_273806_1	1132855.KB913035_gene2513	4.45e-68	215.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,2KM0P@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
k59_273806_2	203122.Sde_3161	1.53e-24	103.0	COG1290@1|root,COG2857@1|root,COG1290@2|Bacteria,COG2857@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,465NG@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
k59_1213980_1	309803.CTN_1933	0.000259	48.1	COG4796@1|root,COG4796@2|Bacteria,2GDBK@200918|Thermotogae	200918|Thermotogae	U	Belongs to the GSP D family	-	-	-	-	-	-	-	-	-	-	-	-	STN,Secretin
k59_351976_1	1121405.dsmv_2117	5.86e-51	169.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,42QDS@68525|delta/epsilon subdivisions,2WMQ3@28221|Deltaproteobacteria,2MJQ8@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
k59_704245_1	911239.CF149_04086	7.52e-56	191.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,1RZBX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_76080_1	883.DvMF_2659	1.07e-51	174.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2M92B@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_76080_2	177437.HRM2_31360	1.9e-09	56.6	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria,2MIJ1@213118|Desulfobacterales	28221|Deltaproteobacteria	KO	TIGRFAM hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
k59_588986_1	405948.SACE_3101	3.07e-72	239.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4DXAF@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_863194_1	935567.JAES01000004_gene125	5.19e-21	93.2	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,1X30A@135614|Xanthomonadales	135614|Xanthomonadales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
k59_706457_1	296591.Bpro_2539	4.86e-112	338.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,2VNBZ@28216|Betaproteobacteria,4AD8C@80864|Comamonadaceae	28216|Betaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_549832_1	391038.Bphy_3993	6.08e-46	166.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,1K38N@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_941703_1	765911.Thivi_4139	1.19e-48	171.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales	1224|Proteobacteria	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_902390_1	1094184.KWO_0106000	1.72e-56	179.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1X643@135614|Xanthomonadales	135614|Xanthomonadales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_236358_1	439235.Dalk_1928	1.06e-144	416.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MHTQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_471469_5	61622.XP_010375453.1	7.22e-09	55.5	28P2N@1|root,2QVP2@2759|Eukaryota,39RFA@33154|Opisthokonta,3BAK2@33208|Metazoa,3CX0D@33213|Bilateria,480Z4@7711|Chordata,494U9@7742|Vertebrata,3J40U@40674|Mammalia,35EST@314146|Euarchontoglires,4MC7M@9443|Primates,36AD6@314294|Cercopithecoidea	33208|Metazoa	U	Raftlin, lipid raft linker 1	RFTN1	GO:0001765,GO:0001816,GO:0002218,GO:0002221,GO:0002224,GO:0002250,GO:0002252,GO:0002253,GO:0002376,GO:0002429,GO:0002443,GO:0002449,GO:0002456,GO:0002457,GO:0002460,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005886,GO:0006403,GO:0006810,GO:0006886,GO:0006955,GO:0007154,GO:0007165,GO:0007166,GO:0008104,GO:0008150,GO:0009987,GO:0010033,GO:0012505,GO:0014070,GO:0015031,GO:0015833,GO:0015931,GO:0016020,GO:0016043,GO:0019882,GO:0022607,GO:0023052,GO:0031347,GO:0031349,GO:0031410,GO:0031579,GO:0031982,GO:0032501,GO:0032594,GO:0032596,GO:0032620,GO:0032991,GO:0033036,GO:0033227,GO:0034138,GO:0034613,GO:0040007,GO:0040008,GO:0040009,GO:0040010,GO:0042221,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043330,GO:0043331,GO:0044085,GO:0044091,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0045088,GO:0045089,GO:0045121,GO:0045184,GO:0045927,GO:0046907,GO:0048518,GO:0048583,GO:0048584,GO:0050657,GO:0050658,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050851,GO:0050852,GO:0050853,GO:0050896,GO:0051179,GO:0051234,GO:0051236,GO:0051641,GO:0051649,GO:0051668,GO:0051716,GO:0061024,GO:0065007,GO:0070727,GO:0071702,GO:0071705,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0080134,GO:0090150,GO:0097159,GO:0097708,GO:0098589,GO:0098805,GO:0098857,GO:1901363,GO:1901698,GO:1903044	-	-	-	-	-	-	-	-	-	-	Raftlin
k59_157936_1	316067.Geob_1241	4.92e-62	206.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43TM0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_471484_1	1117315.AHCA01000004_gene652	7.88e-50	181.0	COG1629@1|root,COG1629@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,2Q0I6@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_432314_1	1266925.JHVX01000001_gene2679	5.74e-61	213.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,372V5@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_9
k59_980868_1	565045.NOR51B_1765	5.26e-12	64.7	COG0526@1|root,COG0526@2|Bacteria,1R3WA@1224|Proteobacteria	1224|Proteobacteria	CO	methylamine dehydrogenase accessory protein MauD	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
k59_980868_2	1522072.IL54_1392	3.83e-09	60.1	COG2259@1|root,COG2259@2|Bacteria,1NAMA@1224|Proteobacteria,2TX24@28211|Alphaproteobacteria,2K76Y@204457|Sphingomonadales	204457|Sphingomonadales	S	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	MauE
k59_1493_2	196162.Noca_4311	7.48e-24	104.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4DQST@85009|Propionibacteriales	201174|Actinobacteria	T	ATP-binding region, ATPase domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_628240_1	9593.ENSGGOP00000016614	2.12e-22	92.4	2A5I7@1|root,2RY9P@2759|Eukaryota,39WY2@33154|Opisthokonta,3BI5T@33208|Metazoa,3CT28@33213|Bilateria,47Z1D@7711|Chordata,4912K@7742|Vertebrata,3J8DQ@40674|Mammalia,35K50@314146|Euarchontoglires,4M6SH@9443|Primates,4N59Z@9604|Hominidae	33208|Metazoa	C	response to leukemia inhibitory factor	LAPTM5	GO:0000323,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0034097,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071345,GO:0071944,GO:1990823,GO:1990830	-	ko:K12387	ko04142,map04142	-	-	-	ko00000,ko00001	-	-	-	Mtp
k59_706589_1	290397.Adeh_2572	7.22e-40	136.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WNNV@28221|Deltaproteobacteria,2Z08H@29|Myxococcales	28221|Deltaproteobacteria	C	Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_510621_1	1499967.BAYZ01000105_gene3482	4.07e-62	211.0	COG0243@1|root,COG0243@2|Bacteria,2NPRJ@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	dmsA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0033797,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494	1.8.5.3,1.8.5.5,1.97.1.9	ko:K07306,ko:K07309,ko:K07310,ko:K08352	ko00450,ko00920,ko01120,map00450,map00920,map01120	-	R07229,R09501,R10149	RC02420,RC02555,RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.3,5.A.3.5	-	iE2348C_1286.E2348C_1672,iECSE_1348.ECSE_0952,iNRG857_1313.NRG857_07945,iSFV_1184.SFV_1557,iZ_1308.Z1240	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_863360_1	1121106.JQKB01000006_gene1318	2.24e-59	199.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria,2JSIF@204441|Rhodospirillales	204441|Rhodospirillales	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2,Pyr_redox_3
k59_863360_2	565045.NOR51B_1645	2.38e-42	153.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_902471_1	1209072.ALBT01000033_gene1609	4.27e-20	96.7	COG4774@1|root,COG4774@2|Bacteria,1R6E9@1224|Proteobacteria,1RSF6@1236|Gammaproteobacteria,1FFV3@10|Cellvibrio	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_197259_1	1224746.B932_0671	9.82e-61	201.0	COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,2TRPW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_784925_1	123214.PERMA_0273	5.39e-08	57.4	COG0071@1|root,COG0071@2|Bacteria,2G4AZ@200783|Aquificae	200783|Aquificae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_275584_1	756272.Plabr_2966	3.36e-07	57.8	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_980907_1	1380394.JADL01000002_gene1232	7.24e-09	61.6	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRQD@28211|Alphaproteobacteria,2JZMC@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Sugar (and other) transporter	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
k59_158038_1	1123269.NX02_10930	1.29e-108	328.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2TS24@28211|Alphaproteobacteria,2K39V@204457|Sphingomonadales	204457|Sphingomonadales	F	Thymidine phosphorylase	-	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
k59_158038_2	1380391.JIAS01000014_gene2237	1.49e-43	151.0	COG5285@1|root,COG5285@2|Bacteria,1Q78R@1224|Proteobacteria,2TSX3@28211|Alphaproteobacteria,2JVRS@204441|Rhodospirillales	204441|Rhodospirillales	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
k59_706652_1	270374.MELB17_15212	8.08e-45	161.0	COG3203@1|root,COG3203@2|Bacteria,1RIIY@1224|Proteobacteria	1224|Proteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
k59_275656_1	1232437.KL662020_gene705	2.43e-97	298.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_980954_1	1125863.JAFN01000001_gene164	3.91e-103	308.0	COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,42PNV@68525|delta/epsilon subdivisions,2WJVJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1096474_1	1232437.KL661961_gene2966	6.46e-57	199.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2MIIB@213118|Desulfobacterales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1096502_1	123899.JPQP01000023_gene3148	2.85e-37	136.0	COG0160@1|root,COG0160@2|Bacteria,1MX0Y@1224|Proteobacteria,2VMYT@28216|Betaproteobacteria,3T5PX@506|Alcaligenaceae	28216|Betaproteobacteria	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k59_155864_1	1499967.BAYZ01000076_gene842	4.33e-20	96.3	COG0457@1|root,COG0457@2|Bacteria,2NQJ6@2323|unclassified Bacteria	2|Bacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
k59_665322_1	1144319.PMI16_04621	1.08e-13	70.9	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,47263@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_665322_2	1279015.KB908454_gene700	7.15e-76	233.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1Y493@135624|Aeromonadales	135624|Aeromonadales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
k59_470081_1	477974.Daud_1279	2.15e-110	327.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,260XK@186807|Peptococcaceae	186801|Clostridia	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	-	-	1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73	ko:K00052,ko:K07246	ko00290,ko00630,ko00650,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00630,map00650,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00215,R00994,R01751,R02545,R04426,R06180,R10052	RC00084,RC00105,RC00417,RC00594,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_470100_1	292415.Tbd_0872	6.32e-92	287.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,2VHJ5@28216|Betaproteobacteria,1KS3F@119069|Hydrogenophilales	119069|Hydrogenophilales	C	FAD binding domain	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
k59_155973_1	1380355.JNIJ01000009_gene1825	1.87e-31	117.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2TT14@28211|Alphaproteobacteria,3JR2J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
k59_77486_1	414684.RC1_0905	7.72e-87	268.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2TS5P@28211|Alphaproteobacteria,2JQTH@204441|Rhodospirillales	204441|Rhodospirillales	S	protein conserved in bacteria	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k59_746308_1	85643.Tmz1t_0645	2e-29	120.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,2KYC7@206389|Rhodocyclales	206389|Rhodocyclales	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
k59_628812_2	472759.Nhal_2152	3.63e-71	226.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria,1X25G@135613|Chromatiales	135613|Chromatiales	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
k59_158537_1	1249627.D779_3901	7.04e-109	322.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1WX0B@135613|Chromatiales	135613|Chromatiales	O	heat shock protein DnaJ	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
k59_511268_1	1168067.JAGP01000001_gene289	2.2e-16	79.7	COG2207@1|root,COG2207@2|Bacteria,1Q3UX@1224|Proteobacteria,1RS88@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_903075_1	246200.SPO1209	7.33e-103	314.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2TS1C@28211|Alphaproteobacteria,4NBNW@97050|Ruegeria	28211|Alphaproteobacteria	S	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
k59_628841_1	335543.Sfum_0268	5.81e-90	278.0	COG0034@1|root,COG0034@2|Bacteria,1R7JX@1224|Proteobacteria,42MAC@68525|delta/epsilon subdivisions,2WKFD@28221|Deltaproteobacteria,2MQ6P@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Glutamine amidotransferase domain	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
k59_981556_1	484022.Fphi_0338	6.2e-82	256.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,1RPGZ@1236|Gammaproteobacteria,4604C@72273|Thiotrichales	72273|Thiotrichales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
k59_589747_1	472759.Nhal_0562	1.41e-41	139.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,1WYZ3@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
k59_589747_2	545276.KB898732_gene2462	9.63e-14	64.3	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1WZA6@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
k59_746384_1	945550.VISI1226_19509	8.57e-32	119.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1XVZI@135623|Vibrionales	135623|Vibrionales	D	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_158590_1	261292.Nit79A3_2730	4.01e-173	501.0	COG3039@1|root,COG3039@2|Bacteria,1Q9GN@1224|Proteobacteria,2WCRD@28216|Betaproteobacteria,373TB@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
k59_354599_1	1047013.AQSP01000114_gene705	1.32e-87	269.0	COG3385@1|root,COG3385@2|Bacteria,2NQNF@2323|unclassified Bacteria	2|Bacteria	L	Domain of unknown function (DUF4372)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_197902_1	1131269.AQVV01000020_gene2194	4.53e-33	124.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	oppB	-	-	ko:K02033,ko:K13894	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
k59_197902_2	1469245.JFBG01000011_gene839	8.27e-66	223.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria	1224|Proteobacteria	E	ABC-Type Dipeptide Transport System Periplasmic Component	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_276255_1	1249627.D779_3250	6.64e-92	280.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1WX6G@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
k59_1099166_1	384765.SIAM614_26548	2.75e-83	274.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,2TQXU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
k59_824878_1	879212.DespoDRAFT_03401	2.71e-25	103.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,2MI7M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM phosphoesterase RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
k59_824908_1	316275.VSAL_I0238	2.47e-21	95.1	COG0438@1|root,COG0438@2|Bacteria,1R7VT@1224|Proteobacteria,1SYK1@1236|Gammaproteobacteria,1Y2U5@135623|Vibrionales	135623|Vibrionales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_197947_1	264732.Moth_1605	1.47e-21	87.0	arCOG10385@1|root,32SEM@2|Bacteria,1VD5W@1239|Firmicutes,2523F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_197947_2	335543.Sfum_1149	1.35e-40	142.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria,2MQSD@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
k59_472227_2	243365.CV_1639	8.87e-23	94.0	COG3791@1|root,COG3791@2|Bacteria,1N6S5@1224|Proteobacteria,2VWNN@28216|Betaproteobacteria,2KS8F@206351|Neisseriales	206351|Neisseriales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
k59_2290_1	870187.Thini_2685	4.39e-51	172.0	COG2878@1|root,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Fe-S cluster	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
k59_864154_1	395493.BegalDRAFT_0992	2.1e-09	61.2	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1T24Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	2.7.7.65	ko:K20954	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
k59_1059908_1	1121405.dsmv_3644	4.4e-55	195.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MIYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_1020904_1	713586.KB900536_gene533	8.95e-52	177.0	COG2367@1|root,COG2367@2|Bacteria,1R4Y9@1224|Proteobacteria	1224|Proteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
k59_394078_1	509191.AEDB02000093_gene3425	4.92e-13	68.2	COG2122@1|root,COG2122@2|Bacteria,1TQ6A@1239|Firmicutes,249KT@186801|Clostridia,3WNIH@541000|Ruminococcaceae	186801|Clostridia	S	PFAM ApbE family	-	-	-	ko:K09740	-	-	-	-	ko00000	-	-	-	-
k59_394078_2	335543.Sfum_2126	5.57e-17	75.9	COG0537@1|root,COG0537@2|Bacteria,1RHYQ@1224|Proteobacteria,42SEG@68525|delta/epsilon subdivisions,2WPFW@28221|Deltaproteobacteria,2MRQA@213462|Syntrophobacterales	28221|Deltaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	CwfJ_C_1,HIT
k59_1177531_1	1041147.AUFB01000001_gene4554	1.06e-31	121.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,4B8YJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	threonine dehydratase	eutB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_864161_1	435908.IDSA_01335	1.26e-102	324.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,2QFP3@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_511524_1	203122.Sde_2150	1.2e-86	261.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,464RA@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_2376	Methyltransf_23
k59_1020933_1	519989.ECTPHS_14004	5.23e-57	190.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1WVZP@135613|Chromatiales	135613|Chromatiales	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
k59_942551_1	641491.DND132_1936	3.73e-80	265.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,43EBY@68525|delta/epsilon subdivisions,2X7W0@28221|Deltaproteobacteria,2MHDJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
k59_511534_2	314285.KT71_07359	3.53e-78	237.0	COG2930@1|root,COG2930@2|Bacteria,1RCYH@1224|Proteobacteria,1SMPZ@1236|Gammaproteobacteria,1J82I@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
k59_433109_1	9913.ENSBTAP00000042255	6.53e-49	165.0	KOG1003@1|root,KOG1003@2759|Eukaryota,38BKJ@33154|Opisthokonta,3B9ZX@33208|Metazoa,3CREJ@33213|Bilateria,4810G@7711|Chordata,48VNR@7742|Vertebrata	33208|Metazoa	Z	Belongs to the tropomyosin family	TPM1	GO:0000302,GO:0001701,GO:0001725,GO:0001726,GO:0001993,GO:0001996,GO:0002027,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003044,GO:0003062,GO:0003065,GO:0003073,GO:0003205,GO:0003206,GO:0003208,GO:0003229,GO:0003231,GO:0003321,GO:0003674,GO:0003779,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005862,GO:0005865,GO:0005884,GO:0005886,GO:0006928,GO:0006936,GO:0006937,GO:0006941,GO:0006950,GO:0006979,GO:0006996,GO:0007010,GO:0007015,GO:0007275,GO:0007507,GO:0007517,GO:0008015,GO:0008016,GO:0008064,GO:0008092,GO:0008150,GO:0008217,GO:0008285,GO:0008307,GO:0008360,GO:0009611,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009987,GO:0010460,GO:0010638,GO:0010639,GO:0010927,GO:0014706,GO:0014910,GO:0014912,GO:0015629,GO:0016020,GO:0016043,GO:0019904,GO:0022603,GO:0022604,GO:0022607,GO:0030016,GO:0030017,GO:0030029,GO:0030030,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030155,GO:0030239,GO:0030334,GO:0030336,GO:0030832,GO:0030833,GO:0030834,GO:0030835,GO:0030837,GO:0031032,GO:0031252,GO:0031253,GO:0031256,GO:0031333,GO:0031529,GO:0032059,GO:0032231,GO:0032233,GO:0032271,GO:0032272,GO:0032432,GO:0032501,GO:0032502,GO:0032535,GO:0032587,GO:0032781,GO:0032879,GO:0032956,GO:0032970,GO:0032989,GO:0032991,GO:0033043,GO:0033275,GO:0033554,GO:0034599,GO:0034614,GO:0036379,GO:0040012,GO:0040013,GO:0042060,GO:0042127,GO:0042221,GO:0042641,GO:0042692,GO:0042802,GO:0042803,GO:0042995,GO:0043009,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043242,GO:0043244,GO:0043254,GO:0043292,GO:0043462,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045214,GO:0045777,GO:0045785,GO:0045823,GO:0046982,GO:0046983,GO:0047485,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048644,GO:0048646,GO:0048660,GO:0048662,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051015,GO:0051128,GO:0051129,GO:0051130,GO:0051146,GO:0051239,GO:0051240,GO:0051270,GO:0051271,GO:0051336,GO:0051345,GO:0051492,GO:0051493,GO:0051494,GO:0051495,GO:0051496,GO:0051693,GO:0051716,GO:0055001,GO:0055002,GO:0055008,GO:0055010,GO:0060047,GO:0060048,GO:0060415,GO:0060537,GO:0061061,GO:0065007,GO:0065008,GO:0065009,GO:0070252,GO:0070887,GO:0070925,GO:0071840,GO:0071944,GO:0072359,GO:0090066,GO:0090257,GO:0097435,GO:0097517,GO:0097718,GO:0098590,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0110020,GO:0110053,GO:0120025,GO:0120036,GO:0120038,GO:1901700,GO:1901701,GO:1901879,GO:1901880,GO:1902903,GO:1902904,GO:1902905,GO:1903522,GO:1903524,GO:1904705,GO:1904706,GO:1904752,GO:1904753,GO:2000145,GO:2000146	-	ko:K09290,ko:K10373,ko:K10374,ko:K10375	ko04260,ko04261,ko05200,ko05206,ko05216,ko05410,ko05414,map04260,map04261,map05200,map05206,map05216,map05410,map05414	-	-	-	ko00000,ko00001,ko04147,ko04812	-	-	-	Tropomyosin,Tropomyosin_1
k59_511543_1	990285.RGCCGE502_18085	1.33e-37	134.0	COG3741@1|root,COG3741@2|Bacteria,1RG2S@1224|Proteobacteria,2U8RG@28211|Alphaproteobacteria,4BB3K@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
k59_785782_1	1042377.AFPJ01000036_gene1233	8.64e-104	315.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_1059941_1	886293.Sinac_3502	2.33e-68	218.0	COG0500@1|root,COG2226@2|Bacteria,2IXEP@203682|Planctomycetes	203682|Planctomycetes	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
k59_2361_1	331869.BAL199_07173	1.11e-117	345.0	COG1638@1|root,COG1638@2|Bacteria,1QV73@1224|Proteobacteria,2TWBZ@28211|Alphaproteobacteria,4BRYQ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	TRAP-type mannitol chloroaromatic compound transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1177579_1	1397527.Q670_01820	1.86e-55	181.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,1XHAN@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
k59_472318_1	1479235.KK366039_gene1914	1.45e-106	314.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales	135619|Oceanospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_1020964_1	521098.Aaci_0499	4.19e-44	157.0	COG2801@1|root,COG2801@2|Bacteria,1TT8V@1239|Firmicutes,4HCE5@91061|Bacilli,279CZ@186823|Alicyclobacillaceae	91061|Bacilli	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28,HTH_29,rve
k59_354793_1	2340.JV46_27570	6.43e-12	62.4	COG2905@1|root,COG2905@2|Bacteria,1MZGY@1224|Proteobacteria,1S86K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_354793_2	642492.Clole_1977	2.81e-05	49.3	COG0347@1|root,COG0347@2|Bacteria,1V20Y@1239|Firmicutes,24G40@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
k59_354793_3	1049564.TevJSym_ai00540	1.66e-26	103.0	arCOG03638@1|root,2Z8W3@2|Bacteria,1N2PH@1224|Proteobacteria,1RMI8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
k59_864209_1	935836.JAEL01000014_gene2071	6.9e-13	73.9	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,1ZBG8@1386|Bacillus	91061|Bacilli	E	COG0747 ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_864212_1	933262.AXAM01000019_gene1134	7.63e-25	96.3	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,2MKA4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
k59_550775_1	311403.Arad_9023	9.32e-137	398.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2U28T@28211|Alphaproteobacteria,4BE1X@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
k59_433145_1	933262.AXAM01000052_gene2016	6.48e-79	248.0	COG2199@1|root,COG3706@2|Bacteria,1R8F2@1224|Proteobacteria,42QMA@68525|delta/epsilon subdivisions,2WKC1@28221|Deltaproteobacteria,2MHN4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DUF484,GGDEF
k59_2403_1	335543.Sfum_0294	2.12e-54	193.0	COG0591@1|root,COG1842@1|root,COG3852@1|root,COG0591@2|Bacteria,COG1842@2|Bacteria,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43CEX@68525|delta/epsilon subdivisions,2X7PW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,PAS
k59_981883_1	1449353.JQMQ01000005_gene2633	3.11e-16	82.8	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,2NGG5@228398|Streptacidiphilus	201174|Actinobacteria	H	MoeA N-terminal region (domain I and II)	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
k59_433168_1	76636.JOEC01000002_gene2217	2.55e-06	49.7	COG5361@1|root,COG5361@2|Bacteria,2GKTA@201174|Actinobacteria,4FMDK@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_433168_2	196367.JNFG01000065_gene931	1.53e-57	194.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria	1224|Proteobacteria	S	s cog5361	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_1059991_1	1229780.BN381_240014	1.79e-80	261.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,3UWFI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_511628_1	177437.HRM2_23440	2.32e-125	382.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2MHNT@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
k59_80632_1	1197706.AKKK01000038_gene1343	5.47e-27	112.0	COG2182@1|root,COG2182@2|Bacteria,2HST8@201174|Actinobacteria,1W7NN@1268|Micrococcaceae	201174|Actinobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
k59_158875_1	78245.Xaut_2834	3.89e-19	85.5	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,3EYBT@335928|Xanthobacteraceae	28211|Alphaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
k59_158875_2	394.NGR_c08980	1.37e-45	156.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2TRD9@28211|Alphaproteobacteria,4B900@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_2457_1	574966.KB898651_gene2140	3.37e-23	100.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_315630_1	933262.AXAM01000101_gene2553	7.64e-76	233.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42NZS@68525|delta/epsilon subdivisions,2WINI@28221|Deltaproteobacteria,2MI5U@213118|Desulfobacterales	28221|Deltaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_80675_1	1182553.XP_007748299.1	4.73e-24	105.0	291XQ@1|root,2R8TZ@2759|Eukaryota,397WV@33154|Opisthokonta,3NVPG@4751|Fungi,3QRJC@4890|Ascomycota,20G1G@147545|Eurotiomycetes	4751|Fungi	S	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
k59_691516_2	502025.Hoch_2005	7.8e-09	56.6	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2WJMT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169	PEPCK_ATP
k59_1161524_1	335543.Sfum_0208	3.87e-78	248.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2MRBS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_1200976_2	1265505.ATUG01000001_gene4786	3.09e-18	83.2	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,42MIS@68525|delta/epsilon subdivisions,2WMK7@28221|Deltaproteobacteria,2MJNM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_1046108_1	553385.JEMF01000017_gene1138	0.000528	45.4	COG0845@1|root,COG0845@2|Bacteria,1R4JA@1224|Proteobacteria,1RPS5@1236|Gammaproteobacteria,1XJG3@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1046108_2	1541065.JRFE01000057_gene6337	2.09e-08	57.8	COG0845@1|root,COG0845@2|Bacteria,1G1I8@1117|Cyanobacteria,3VJDC@52604|Pleurocapsales	1117|Cyanobacteria	M	YtkA-like	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23,YtkA
k59_925386_1	880072.Desac_2364	5.5e-41	146.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,2MQIS@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_338859_1	857087.Metme_0620	1.02e-34	126.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1XEWE@135618|Methylococcales	135618|Methylococcales	H	riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_925402_1	485915.Dret_1799	2.27e-55	179.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,42RE2@68525|delta/epsilon subdivisions,2WNEN@28221|Deltaproteobacteria,2MB2K@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
k59_338879_1	1265505.ATUG01000002_gene1615	1.88e-36	137.0	COG0247@1|root,COG1150@1|root,COG0247@2|Bacteria,COG1150@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria,2MJHX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_422677_1	172088.AUGA01000026_gene274	9.43e-50	176.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_19,TPR_2
k59_338885_1	1123060.JONP01000028_gene3708	2.11e-12	72.4	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2UQ0A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
k59_966184_1	1121405.dsmv_3288	6.58e-33	118.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MMAC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_966184_2	177437.HRM2_28220	1.61e-34	126.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42R8Z@68525|delta/epsilon subdivisions,2WMXX@28221|Deltaproteobacteria,2MKJX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_537739_1	933262.AXAM01000016_gene165	4.23e-57	186.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,2MI2P@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_495677_1	511062.GU3_01905	5.05e-97	299.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1Y3Y3@135624|Aeromonadales	135624|Aeromonadales	E	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_1082488_1	42099.EPrPV00000020805	1.22e-42	160.0	COG0265@1|root,KOG1421@2759|Eukaryota,1MA90@121069|Pythiales	121069|Pythiales	O	Pro-apoptotic serine protease nma111. Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,Trypsin_2
k59_613384_1	1379698.RBG1_1C00001G0427	6.8e-44	157.0	COG2256@1|root,COG2256@2|Bacteria,2NNTG@2323|unclassified Bacteria	2|Bacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_1244001_1	335543.Sfum_3971	1.39e-104	316.0	COG2308@1|root,COG2308@2|Bacteria,1NG4H@1224|Proteobacteria,42WK0@68525|delta/epsilon subdivisions,2WS0X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_142282_1	748449.Halha_2011	3.48e-32	127.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WAC6@53433|Halanaerobiales	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,RnfC_N,SLBB
k59_730486_1	573370.DMR_17610	3.3e-72	218.0	COG2033@1|root,COG2033@2|Bacteria,1RHE0@1224|Proteobacteria,42SB9@68525|delta/epsilon subdivisions,2WP2D@28221|Deltaproteobacteria,2MBEZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Desulfoferrodoxin ferrous iron-binding region	dfx	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
k59_142293_1	580332.Slit_0818	2.56e-64	206.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,2VWPY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
k59_887485_1	298386.PBPRA3351	2.09e-22	97.1	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria,1XSXN@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_691613_1	1123366.TH3_02775	1.53e-42	151.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,2TVBG@28211|Alphaproteobacteria,2JSA7@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_966246_2	926569.ANT_04650	4.19e-54	183.0	COG0031@1|root,COG0031@2|Bacteria,2G8GE@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
k59_378683_1	96561.Dole_1861	1.74e-82	253.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_537818_1	933262.AXAM01000004_gene2364	1.81e-27	110.0	COG0438@1|root,COG0438@2|Bacteria,1R8YI@1224|Proteobacteria,42N8I@68525|delta/epsilon subdivisions,2WIYJ@28221|Deltaproteobacteria,2MMJB@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_925488_1	56780.SYN_00544	3.96e-91	280.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,2MQ73@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_769664_1	1298867.AUES01000001_gene1663	1.87e-78	245.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,2TR29@28211|Alphaproteobacteria,3K2MT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class I and II	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1122657_1	644107.SL1157_A0272	6.57e-09	58.2	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,4ND9S@97050|Ruegeria	28211|Alphaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
k59_1122657_2	95619.PM1_0201870	1.86e-69	213.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
k59_1122657_3	2340.JV46_11900	6.13e-91	275.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,1J5J9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the dihydroorotate dehydrogenase family	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,NAD_binding_1
k59_422794_1	9601.ENSPPYP00000014307	8.89e-187	540.0	COG1241@1|root,KOG0480@2759|Eukaryota,38C40@33154|Opisthokonta,3B955@33208|Metazoa,3D0KM@33213|Bilateria,480N7@7711|Chordata,48ZJB@7742|Vertebrata,3J46S@40674|Mammalia,35KVM@314146|Euarchontoglires,4MBBH@9443|Primates,4MZ15@9604|Hominidae	33208|Metazoa	L	Minichromosome maintenance complex component 6	MCM6	GO:0000003,GO:0000082,GO:0000166,GO:0000278,GO:0000785,GO:0002064,GO:0002065,GO:0002066,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006275,GO:0006277,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007276,GO:0007281,GO:0007292,GO:0007304,GO:0007306,GO:0007307,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009653,GO:0009888,GO:0009889,GO:0009987,GO:0010556,GO:0010927,GO:0016043,GO:0017076,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0022607,GO:0030154,GO:0030174,GO:0030554,GO:0030703,GO:0030707,GO:0030855,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032392,GO:0032501,GO:0032502,GO:0032504,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032989,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042555,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044843,GO:0046483,GO:0048468,GO:0048477,GO:0048609,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0051276,GO:0051704,GO:0060255,GO:0060429,GO:0065007,GO:0070013,GO:0071103,GO:0071704,GO:0071840,GO:0071897,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903047,GO:2000112	3.6.4.12	ko:K02542	ko03030,ko04110,ko04111,ko04113,map03030,map04110,map04111,map04113	M00285	-	-	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	MCM,MCM_N,MCM_OB
k59_691645_1	1089550.ATTH01000001_gene1046	1.92e-16	81.6	COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,1FIPV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Cytochrome c-type biogenesis protein CcmF C-terminal	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_691645_2	880073.Calab_2350	2.88e-16	74.3	COG2332@1|root,COG2332@2|Bacteria,2NQ2A@2323|unclassified Bacteria	2|Bacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
k59_24951_1	675635.Psed_0515	2.95e-13	68.9	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,4DYUC@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
k59_24951_2	1123355.JHYO01000008_gene2679	1.37e-19	88.2	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,36ZEK@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
k59_807748_1	105559.Nwat_3075	3.16e-79	264.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
k59_422825_1	565045.NOR51B_699	8.29e-66	207.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,1RMFX@1236|Gammaproteobacteria,1J591@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
k59_422825_2	998088.B565_3072	1.35e-24	99.4	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1Y3GJ@135624|Aeromonadales	135624|Aeromonadales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
k59_300394_1	1479239.JQMU01000001_gene2123	6.86e-23	101.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,2K29X@204457|Sphingomonadales	204457|Sphingomonadales	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_537891_1	478801.Ksed_05530	4.58e-28	117.0	COG1404@1|root,COG2247@1|root,COG1404@2|Bacteria,COG2247@2|Bacteria,2HF5P@201174|Actinobacteria,1ZWEY@145357|Dermacoccaceae	2|Bacteria	M	Belongs to the peptidase S8 family	vpr	GO:0005575,GO:0005576	-	ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	CW_binding_2,FlgD_ig,Inhibitor_I9,PA,Peptidase_S8,SLH,fn3_5
k59_887562_1	879212.DespoDRAFT_01333	1.04e-101	309.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1201163_1	748247.AZKH_0434	5.08e-103	311.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKRZ@28216|Betaproteobacteria,2KZSM@206389|Rhodocyclales	206389|Rhodocyclales	H	Aminotransferase class-III	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k59_181925_1	591157.SSLG_00072	4.43e-08	56.2	COG3293@1|root,COG3293@2|Bacteria,2IHX5@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_769735_1	1121405.dsmv_3291	2.18e-56	183.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,42WT2@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_24993_1	1167006.UWK_00886	1.84e-27	107.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,2MIMW@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_24993_2	1041146.ATZB01000011_gene1020	9.14e-22	89.4	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2U98B@28211|Alphaproteobacteria,4BFMH@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the ArsC family	MA20_27840	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
k59_1244149_1	118168.MC7420_5670	2.54e-63	207.0	COG3875@1|root,COG3875@2|Bacteria,1G82E@1117|Cyanobacteria,1HDBH@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
k59_224075_1	1042375.AFPL01000030_gene474	1.31e-16	77.8	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,466TU@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
k59_224075_2	314278.NB231_14188	3.2e-41	137.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,1X0ZV@135613|Chromatiales	135613|Chromatiales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
k59_769749_1	1085623.GNIT_1254	3.26e-61	197.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,467TG@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_769749_2	1267005.KB911266_gene1250	1.61e-17	81.3	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,3N7U4@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_25009_1	756067.MicvaDRAFT_4025	1.26e-30	126.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1H7GA@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal Transduction Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
k59_848247_1	1265505.ATUG01000001_gene4625	4.44e-58	189.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,42N5K@68525|delta/epsilon subdivisions,2WK1G@28221|Deltaproteobacteria,2MHYP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	bamA	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_1082635_1	666685.R2APBS1_3946	1.5e-36	138.0	COG1577@1|root,COG1577@2|Bacteria,1N400@1224|Proteobacteria,1SC29@1236|Gammaproteobacteria,1XAB2@135614|Xanthomonadales	135614|Xanthomonadales	I	GHMP kinases N terminal domain	-	-	2.7.4.2	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R03245	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
k59_1201200_1	187272.Mlg_1870	4.47e-114	349.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1WXQF@135613|Chromatiales	135613|Chromatiales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
k59_1122768_1	1234595.C725_2704	1.56e-10	64.3	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_925598_1	1121405.dsmv_0457	1.17e-71	233.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MHPE@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_105283_1	1356854.N007_18165	1.92e-17	84.3	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,2798R@186823|Alicyclobacillaceae	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS_4
k59_769784_1	545276.KB898729_gene1659	4.04e-50	166.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1WWSM@135613|Chromatiales	135613|Chromatiales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_730646_2	1434929.X946_3157	1.02e-58	193.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VIY2@28216|Betaproteobacteria,1KBXW@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	yfdH	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
k59_378893_1	382464.ABSI01000011_gene2419	3.84e-68	229.0	COG1472@1|root,COG1472@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_300496_1	1123508.JH636443_gene4639	8.14e-10	60.8	COG1005@1|root,COG1005@2|Bacteria,2IXH1@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
k59_27285_1	314285.KT71_12795	2.39e-111	333.0	COG0624@1|root,COG0624@2|Bacteria,1R96A@1224|Proteobacteria,1RSD6@1236|Gammaproteobacteria,1J8ZH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_968896_1	933262.AXAM01000048_gene2590	2.06e-69	221.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2MIEV@213118|Desulfobacterales	28221|Deltaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
k59_809902_1	1469245.JFBG01000019_gene1125	2.08e-32	125.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1WXI8@135613|Chromatiales	135613|Chromatiales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_458653_1	1333998.M2A_1564	1.08e-85	277.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria,4BPKQ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_1048063_1	1397528.Q671_02270	9.24e-50	165.0	COG0813@1|root,COG0813@2|Bacteria,1MUW6@1224|Proteobacteria,1RMMA@1236|Gammaproteobacteria,1XI9S@135619|Oceanospirillales	135619|Oceanospirillales	F	Catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_381924_1	1090320.KB900605_gene2038	1.25e-56	199.0	COG1629@1|root,COG1629@2|Bacteria,1N7IE@1224|Proteobacteria,2TVJS@28211|Alphaproteobacteria,2KCZ8@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_616308_1	398767.Glov_1062	8.23e-10	60.8	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
k59_341510_1	555779.Dthio_PD2895	5.49e-62	199.0	COG0582@1|root,COG0582@2|Bacteria,1RCN8@1224|Proteobacteria,42RD9@68525|delta/epsilon subdivisions,2WMVF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	viral genome integration into host DNA	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
k59_772112_1	444862.E3SM97_9CAUD	1.51e-73	223.0	4QAUK@10239|Viruses,4QWEQ@35237|dsDNA viruses  no RNA stage,4QQ1Z@28883|Caudovirales,4QIGD@10662|Myoviridae	10662|Myoviridae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_341520_1	1007104.SUS17_1739	1.24e-40	155.0	COG3203@1|root,COG3203@2|Bacteria,1MX4Q@1224|Proteobacteria,2TUSU@28211|Alphaproteobacteria,2K1P5@204457|Sphingomonadales	204457|Sphingomonadales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_2
k59_733005_1	99598.Cal7507_1431	5.57e-47	168.0	COG1070@1|root,COG1070@2|Bacteria,1G0G6@1117|Cyanobacteria,1HIBN@1161|Nostocales	1117|Cyanobacteria	G	PFAM FGGY family of carbohydrate kinases, N-terminal domain	xylB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019150,GO:0019200,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
k59_576237_1	936455.KI421499_gene3413	1.47e-89	279.0	COG2303@1|root,COG2303@2|Bacteria,1N0NP@1224|Proteobacteria,2TQSK@28211|Alphaproteobacteria,3JVQR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	GMC oxidoreductase	MA20_00585	-	1.1.3.47	ko:K16873	ko00365,ko01120,map00365,map01120	-	R10212,R10216,R10858	RC00075,RC03291	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
k59_317974_2	488538.SAR116_0663	5.11e-45	155.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,4BQAI@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
k59_670755_1	879212.DespoDRAFT_02066	9.28e-99	297.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2WJD7@28221|Deltaproteobacteria,2MIY0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM sodium ion-translocating decarboxylase, beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
k59_592441_1	522306.CAP2UW1_3280	7.64e-16	82.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VIMP@28216|Betaproteobacteria	28216|Betaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
k59_788359_1	371042.NG99_13265	4.82e-28	115.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,1RPSI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_709678_1	1267533.KB906741_gene430	1.41e-27	115.0	COG0210@1|root,COG0210@2|Bacteria,3Y2W8@57723|Acidobacteria,2JIDH@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_984648_1	61622.XP_010354745.1	0.0	889.0	KOG4295@1|root,KOG3540@2759|Eukaryota,38CIE@33154|Opisthokonta,3BBR8@33208|Metazoa,3CUJD@33213|Bilateria,483EW@7711|Chordata,48VZ1@7742|Vertebrata,3J8QG@40674|Mammalia,35AXW@314146|Euarchontoglires,4M8AT@9443|Primates,35XCC@314294|Cercopithecoidea	33208|Metazoa	S	Amyloid beta	APLP2	GO:0000003,GO:0000902,GO:0001932,GO:0001967,GO:0002119,GO:0002164,GO:0002576,GO:0003008,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005788,GO:0005886,GO:0006066,GO:0006464,GO:0006629,GO:0006807,GO:0006810,GO:0006873,GO:0006875,GO:0006878,GO:0006887,GO:0006950,GO:0007154,GO:0007165,GO:0007176,GO:0007186,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007422,GO:0007610,GO:0007611,GO:0007613,GO:0007614,GO:0007616,GO:0007617,GO:0007618,GO:0007626,GO:0007631,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009611,GO:0009628,GO:0009653,GO:0009791,GO:0009966,GO:0009987,GO:0010171,GO:0010469,GO:0010646,GO:0010941,GO:0012505,GO:0012506,GO:0016020,GO:0016021,GO:0016043,GO:0016125,GO:0016192,GO:0016319,GO:0018996,GO:0019098,GO:0019220,GO:0019222,GO:0019538,GO:0019725,GO:0019953,GO:0022008,GO:0022404,GO:0022414,GO:0023051,GO:0023052,GO:0030003,GO:0030030,GO:0030141,GO:0030154,GO:0030182,GO:0030198,GO:0030659,GO:0030667,GO:0030900,GO:0030901,GO:0031090,GO:0031091,GO:0031092,GO:0031175,GO:0031224,GO:0031323,GO:0031399,GO:0031410,GO:0031974,GO:0031982,GO:0032268,GO:0032501,GO:0032502,GO:0032504,GO:0032940,GO:0032989,GO:0032990,GO:0036211,GO:0036477,GO:0042058,GO:0042303,GO:0042325,GO:0042395,GO:0042592,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043062,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0043412,GO:0043549,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045055,GO:0045859,GO:0046903,GO:0046916,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048609,GO:0048666,GO:0048678,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050730,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050808,GO:0050877,GO:0050885,GO:0050890,GO:0050896,GO:0050905,GO:0051098,GO:0051171,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051338,GO:0051602,GO:0051704,GO:0051705,GO:0051716,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0060322,GO:0060548,GO:0061097,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097458,GO:0097708,GO:0098588,GO:0098771,GO:0098805,GO:0099503,GO:0120025,GO:0120036,GO:0120039,GO:1901184,GO:1901214,GO:1901215,GO:1901360,GO:1901363,GO:1901564,GO:1901615,GO:1902652	-	ko:K04520,ko:K08117	ko04726,ko05010,map04726,map05010	-	-	-	ko00000,ko00001,ko00535,ko00536	-	-	-	APP_Cu_bd,APP_E2,APP_N,APP_amyloid,Kunitz_BPTI
k59_984655_1	933262.AXAM01000013_gene1317	1.29e-73	224.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,42SJS@68525|delta/epsilon subdivisions,2WP7N@28221|Deltaproteobacteria,2MK9P@213118|Desulfobacterales	28221|Deltaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
k59_1101791_1	335543.Sfum_3191	3.32e-26	99.4	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
k59_945114_1	187272.Mlg_2774	6.48e-78	253.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1WVYV@135613|Chromatiales	135613|Chromatiales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_1062596_1	9785.ENSLAFP00000011996	1.02e-117	344.0	KOG3296@1|root,KOG3296@2759|Eukaryota,38FFD@33154|Opisthokonta,3B974@33208|Metazoa,3CT7X@33213|Bilateria,47ZUM@7711|Chordata,48W8D@7742|Vertebrata,3JD80@40674|Mammalia,34ZRT@311790|Afrotheria	33208|Metazoa	U	Mitochondrial import receptor subunit TOM40 homolog	TOMM40	GO:0001666,GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005742,GO:0005743,GO:0005758,GO:0005829,GO:0006605,GO:0006626,GO:0006810,GO:0006811,GO:0006812,GO:0006839,GO:0006886,GO:0006950,GO:0006996,GO:0007005,GO:0007006,GO:0008104,GO:0008150,GO:0008320,GO:0008324,GO:0008565,GO:0009628,GO:0009987,GO:0010941,GO:0010942,GO:0015031,GO:0015075,GO:0015267,GO:0015318,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0017038,GO:0019866,GO:0019867,GO:0022803,GO:0022804,GO:0022838,GO:0022857,GO:0022884,GO:0022890,GO:0030150,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031306,GO:0031307,GO:0031966,GO:0031967,GO:0031968,GO:0031970,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0033036,GO:0033365,GO:0033554,GO:0034220,GO:0034613,GO:0036293,GO:0036294,GO:0042221,GO:0042719,GO:0042886,GO:0042887,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044743,GO:0045184,GO:0046907,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051204,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055085,GO:0061024,GO:0065002,GO:0065007,GO:0070013,GO:0070482,GO:0070585,GO:0070678,GO:0070727,GO:0070887,GO:0071453,GO:0071456,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0072657,GO:0090150,GO:0098573,GO:0098588,GO:0098655,GO:0098796,GO:0098798,GO:0098799,GO:0098805,GO:1904680,GO:1990351,GO:1990542	-	ko:K11518	ko05014,map05014	-	-	-	ko00000,ko00001,ko02000,ko03029	3.A.8.1	-	-	Porin_3
k59_122535_1	335543.Sfum_0195	1.6e-41	139.0	COG4392@1|root,COG4392@2|Bacteria,1NEQP@1224|Proteobacteria,42VHX@68525|delta/epsilon subdivisions,2WRER@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
k59_122535_2	335543.Sfum_0194	1.47e-11	64.3	COG1296@1|root,COG1296@2|Bacteria,1P6U3@1224|Proteobacteria,42QVQ@68525|delta/epsilon subdivisions,2WMW1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM AzlC family protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
k59_239728_1	314278.NB231_06076	2.33e-89	285.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales	135613|Chromatiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_553227_1	720555.BATR1942_09685	1.13e-18	92.8	COG0749@1|root,COG0749@2|Bacteria,1V02Y@1239|Firmicutes,4HD34@91061|Bacilli,1ZM2A@1386|Bacillus	91061|Bacilli	L	3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A,DNA_pol_A_exo1
k59_396922_1	391615.ABSJ01000041_gene2	3.75e-61	199.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1J587@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0025,iJN746.PP_0602	FAD_syn,Flavokinase
k59_1101829_1	485913.Krac_5105	6.74e-10	64.7	COG5659@1|root,COG5659@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
k59_827571_1	391009.Tmel_0803	5.64e-09	60.8	COG1449@1|root,COG4945@1|root,COG1449@2|Bacteria,COG4945@2|Bacteria,2GC51@200918|Thermotogae	200918|Thermotogae	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Glucodextran_C,Glyco_hydro_57
k59_474890_1	441620.Mpop_3793	2.74e-47	159.0	COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,2TUQI@28211|Alphaproteobacteria,1JV6H@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_318055_1	227086.JGI_V11_90065	7.09e-18	85.9	COG0545@1|root,KOG0544@2759|Eukaryota	2759|Eukaryota	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K09568	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_239789_1	1336233.JAEH01000053_gene4112	1.8e-09	63.9	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,2QAD9@267890|Shewanellaceae	1236|Gammaproteobacteria	D	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids	xerC	GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_788446_1	1411123.JQNH01000001_gene1631	1.28e-78	254.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2TR9G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_396982_1	247490.KSU1_C1445	5.59e-27	110.0	COG2015@1|root,COG3119@1|root,COG2015@2|Bacteria,COG3119@2|Bacteria,2IX0Y@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_200602_1	247490.KSU1_B0424	6.73e-68	219.0	COG0758@1|root,COG0758@2|Bacteria,2IX3D@203682|Planctomycetes	203682|Planctomycetes	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
k59_161645_1	326442.PSHAa1356	1.35e-37	137.0	COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,1RRNW@1236|Gammaproteobacteria,2PZYA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	G	COG0477 Permeases of the major facilitator superfamily	malT	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
k59_161645_2	283699.D172_1359	1.01e-59	202.0	COG1082@1|root,COG1082@2|Bacteria,1NNTS@1224|Proteobacteria,1RP3I@1236|Gammaproteobacteria,2PZK9@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	G	Glycosyl-hydrolase 97 N-terminal	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
k59_788456_1	889378.Spiaf_1183	7.62e-26	109.0	COG3735@1|root,COG3735@2|Bacteria,2J73F@203691|Spirochaetes	203691|Spirochaetes	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
k59_1219486_1	765913.ThidrDRAFT_1243	1.06e-72	234.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,1RPDV@1236|Gammaproteobacteria,1WXSP@135613|Chromatiales	135613|Chromatiales	G	alpha beta alpha domain I	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_318070_1	556268.OFAG_01538	1.57e-15	75.5	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria,47246@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	pfkB family carbohydrate kinase	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_670878_1	713587.THITH_02750	2.77e-66	218.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1WW9V@135613|Chromatiales	135613|Chromatiales	J	TIGRFAM ribonuclease, Rne Rng family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_1023872_2	1148.1652026	2.39e-53	182.0	COG0004@1|root,COG0004@2|Bacteria,1G0S8@1117|Cyanobacteria,1H6F7@1142|Synechocystis	1117|Cyanobacteria	U	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	iJN678.amt2	Ammonium_transp
k59_83618_1	582899.Hden_0691	6.31e-47	160.0	COG1148@1|root,COG1148@2|Bacteria,1R882@1224|Proteobacteria,2U526@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_oxidored,Pyr_redox_2
k59_1101921_1	1121405.dsmv_2740	4.84e-33	123.0	COG0726@1|root,COG0726@2|Bacteria,1R5QW@1224|Proteobacteria,42R0U@68525|delta/epsilon subdivisions,2WN0F@28221|Deltaproteobacteria,2MJIM@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334,Polysacc_deac_1
k59_1140840_1	404380.Gbem_0895	4.34e-36	137.0	COG1624@1|root,COG1624@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
k59_709795_1	1510531.JQJJ01000010_gene2093	1.6e-53	174.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2TVKC@28211|Alphaproteobacteria,3JTB7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	MA20_22745	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_161684_1	243090.RB4580	7.71e-72	244.0	COG1480@1|root,COG1480@2|Bacteria,2IYP7@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
k59_866703_1	1167006.UWK_02861	2.03e-128	377.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,42MQV@68525|delta/epsilon subdivisions,2WIZC@28221|Deltaproteobacteria,2MIQG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
k59_161690_1	414684.RC1_0412	2.4e-121	367.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2JPYX@204441|Rhodospirillales	204441|Rhodospirillales	I	COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_357722_3	118161.KB235922_gene3862	7.78e-14	70.5	COG0637@1|root,COG0637@2|Bacteria,1G328@1117|Cyanobacteria	1117|Cyanobacteria	S	HAD-superfamily hydrolase subfamily IA, variant 3	-	-	3.1.3.96,5.4.2.6	ko:K01838,ko:K17623	ko00500,map00500	-	R02728,R11180,R11310	RC00017,RC00408	ko00000,ko00001,ko01000,ko01009	-	-	-	HAD_2
k59_1101949_2	399795.CtesDRAFT_PD1608	6.92e-31	119.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2VI0E@28216|Betaproteobacteria,4ABVU@80864|Comamonadaceae	28216|Betaproteobacteria	L	Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k59_788494_1	395493.BegalDRAFT_3086	4.26e-89	290.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,1RMRH@1236|Gammaproteobacteria,45ZTB@72273|Thiotrichales	72273|Thiotrichales	C	Domain of unknown function (DUF3400)	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
k59_709816_1	96561.Dole_2382	6.55e-54	189.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,42P08@68525|delta/epsilon subdivisions,2WJXV@28221|Deltaproteobacteria,2MI0F@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
k59_1062776_1	926569.ANT_08850	2.51e-89	273.0	COG1173@1|root,COG1173@2|Bacteria,2G7U9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_788531_1	1304888.ATWF01000001_gene1077	1.93e-76	237.0	COG0559@1|root,COG0559@2|Bacteria,2GEK5@200930|Deferribacteres	200930|Deferribacteres	P	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_673886_2	190650.CC_3720	1.18e-61	192.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,2TV8S@28211|Alphaproteobacteria,2KF8H@204458|Caulobacterales	204458|Caulobacterales	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	-	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
k59_987685_1	1442599.JAAN01000020_gene2534	5.57e-76	244.0	COG0624@1|root,COG0624@2|Bacteria,1R96A@1224|Proteobacteria,1RSD6@1236|Gammaproteobacteria,1X5K9@135614|Xanthomonadales	135614|Xanthomonadales	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
k59_7962_1	1397528.Q671_06095	3.14e-82	257.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1XR29@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_46683_1	627192.SLG_27150	1.8e-66	218.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2KCJR@204457|Sphingomonadales	204457|Sphingomonadales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_360910_1	9541.XP_005560018.1	0.0	1046.0	COG0469@1|root,KOG2323@2759|Eukaryota,38BPM@33154|Opisthokonta,3BD41@33208|Metazoa,3CV2P@33213|Bilateria,482Z2@7711|Chordata,48X1U@7742|Vertebrata,3J21U@40674|Mammalia,35NZD@314146|Euarchontoglires,4M9IN@9443|Primates,361KP@314294|Cercopithecoidea	33208|Metazoa	G	Pyruvate kinase	PKM	GO:0000166,GO:0000768,GO:0001666,GO:0001889,GO:0001917,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0005929,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006949,GO:0006950,GO:0007275,GO:0007520,GO:0007525,GO:0007584,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009605,GO:0009611,GO:0009628,GO:0009629,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009744,GO:0009888,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0012501,GO:0014854,GO:0014870,GO:0014902,GO:0016020,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019318,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0030154,GO:0030554,GO:0031099,GO:0031100,GO:0031667,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0032991,GO:0033500,GO:0034285,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035770,GO:0036094,GO:0036293,GO:0036464,GO:0040007,GO:0042060,GO:0042221,GO:0042246,GO:0042562,GO:0042592,GO:0042593,GO:0042692,GO:0042802,GO:0042866,GO:0042995,GO:0043167,GO:0043168,GO:0043186,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043403,GO:0043434,GO:0043436,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048513,GO:0048589,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0048878,GO:0050896,GO:0051146,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055086,GO:0060293,GO:0061008,GO:0061061,GO:0061695,GO:0065003,GO:0065007,GO:0065008,GO:0070324,GO:0070482,GO:0070887,GO:0071310,GO:0071375,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0120025,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902912,GO:1990234,GO:1990904	2.7.1.40	ko:K00873,ko:K12406	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04910,ko04922,ko04930,ko04932,ko04950,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04910,map04922,map04930,map04932,map04950,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
k59_908777_1	1123401.JHYQ01000007_gene537	2.76e-83	259.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,45ZTS@72273|Thiotrichales	72273|Thiotrichales	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1026847_1	765913.ThidrDRAFT_0477	2.3e-42	155.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1WXED@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_321128_4	751994.AGIG01000002_gene896	1.4e-07	51.2	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1J5PI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
k59_86853_1	572546.Arcpr_1848	2.03e-63	202.0	COG0410@1|root,arCOG00924@2157|Archaea,2XT1R@28890|Euryarchaeota,245VS@183980|Archaeoglobi	183980|Archaeoglobi	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_1143978_1	536019.Mesop_1153	3.06e-15	75.1	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2TS1C@28211|Alphaproteobacteria,43J9G@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
k59_1143978_2	666509.RCA23_c11780	8.05e-35	128.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2TSQ3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	amino acid aldolase or racemase	MA20_27460	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
k59_869542_1	1158292.JPOE01000005_gene421	5.89e-24	97.8	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,1KJYP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_869542_2	925775.XVE_1302	1.1e-61	202.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1X56M@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
k59_595694_1	868864.Dester_0415	1.84e-78	252.0	COG1894@1|root,COG1894@2|Bacteria,2G3VA@200783|Aquificae	200783|Aquificae	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00124,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
k59_1026904_2	96561.Dole_2251	1.27e-33	126.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M97@68525|delta/epsilon subdivisions,2WJB4@28221|Deltaproteobacteria,2MJB7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	hmcB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,Fer4_7
k59_595704_1	1123355.JHYO01000006_gene2215	1.09e-66	215.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,36XYA@31993|Methylocystaceae	28211|Alphaproteobacteria	I	Thiolase, C-terminal domain	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_830505_2	795359.TOPB45_0645	3.76e-10	63.5	COG1541@1|root,COG1541@2|Bacteria,2GGUS@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_830516_1	1396858.Q666_07955	1.34e-22	100.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,464US@72275|Alteromonadaceae	1236|Gammaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	ubiF	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008682,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0016705,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663	-	ko:K03184	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R06146,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0662,iBWG_1329.BWG_0533,iE2348C_1286.E2348C_0555,iECDH10B_1368.ECDH10B_0731,iECDH1ME8569_1439.ECDH1ME8569_0631,iETEC_1333.ETEC_0690,iEcDH1_1363.EcDH1_2964,iEcHS_1320.EcHS_A0709,iJO1366.b0662,iJR904.b0662,iSBO_1134.SBO_0526,iSbBS512_1146.SbBS512_E0585,iUMNK88_1353.UMNK88_700,iY75_1357.Y75_RS03450	FAD_binding_3,SE
k59_46797_1	9778.XP_004389369.1	8.63e-118	356.0	KOG0289@1|root,KOG0289@2759|Eukaryota,38CRU@33154|Opisthokonta,3BF9F@33208|Metazoa,3CV5N@33213|Bilateria,486KA@7711|Chordata,48X7K@7742|Vertebrata,3JEMM@40674|Mammalia,34UD7@311790|Afrotheria	33208|Metazoa	S	pre-mRNA-processing factor 19	PRPF19	GO:0000075,GO:0000077,GO:0000209,GO:0000244,GO:0000245,GO:0000349,GO:0000375,GO:0000377,GO:0000381,GO:0000387,GO:0000393,GO:0000398,GO:0000726,GO:0000974,GO:0001701,GO:0001824,GO:0001832,GO:0001833,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005684,GO:0005694,GO:0005737,GO:0005811,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006302,GO:0006303,GO:0006325,GO:0006396,GO:0006397,GO:0006464,GO:0006508,GO:0006629,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0008104,GO:0008150,GO:0008152,GO:0008283,GO:0008380,GO:0008610,GO:0009056,GO:0009057,GO:0009058,GO:0009790,GO:0009792,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010498,GO:0010604,GO:0010628,GO:0010720,GO:0010721,GO:0014013,GO:0014015,GO:0016043,GO:0016070,GO:0016071,GO:0016567,GO:0016604,GO:0016607,GO:0016740,GO:0019219,GO:0019222,GO:0019538,GO:0019787,GO:0022008,GO:0022607,GO:0022613,GO:0022618,GO:0023052,GO:0030154,GO:0030163,GO:0031323,GO:0031325,GO:0031570,GO:0031974,GO:0031981,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033120,GO:0033554,GO:0034450,GO:0034613,GO:0034622,GO:0034641,GO:0035556,GO:0035861,GO:0036211,GO:0040007,GO:0042770,GO:0042802,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043484,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0045595,GO:0045596,GO:0045597,GO:0045664,GO:0045665,GO:0045666,GO:0045685,GO:0045687,GO:0045786,GO:0045935,GO:0046483,GO:0048024,GO:0048026,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048589,GO:0048699,GO:0048710,GO:0048711,GO:0048731,GO:0048856,GO:0048869,GO:0050684,GO:0050685,GO:0050767,GO:0050768,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051093,GO:0051094,GO:0051171,GO:0051173,GO:0051179,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051254,GO:0051276,GO:0051603,GO:0051641,GO:0051716,GO:0051726,GO:0051960,GO:0051961,GO:0051962,GO:0060255,GO:0060284,GO:0061630,GO:0061659,GO:0065003,GO:0065007,GO:0070013,GO:0070534,GO:0070647,GO:0070727,GO:0071006,GO:0071007,GO:0071012,GO:0071013,GO:0071704,GO:0071826,GO:0071840,GO:0072395,GO:0072401,GO:0072422,GO:0080090,GO:0090304,GO:0090734,GO:0140096,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1902494,GO:1903311,GO:1903313,GO:1990904,GO:2000026	2.3.2.27	ko:K10599	ko03040,ko04120,map03040,map04120	M00353,M00355	-	-	ko00000,ko00001,ko00002,ko01000,ko03041,ko03400,ko04121	-	-	-	Prp19,U-box,WD40
k59_752213_1	1185652.USDA257_c37770	9.84e-111	331.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2TQUE@28211|Alphaproteobacteria,4BA9J@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
k59_908842_1	1144275.COCOR_01063	2.4e-54	184.0	COG0596@1|root,COG0596@2|Bacteria,1QVBQ@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_791499_1	1129794.C427_0212	1.03e-191	546.0	COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,1RQK5@1236|Gammaproteobacteria,464XB@72275|Alteromonadaceae	1236|Gammaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
k59_1065830_1	404380.Gbem_3979	4.14e-20	87.8	COG0599@1|root,COG0599@2|Bacteria,1QTZH@1224|Proteobacteria,42TJW@68525|delta/epsilon subdivisions,2X5P7@28221|Deltaproteobacteria,43UQ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_1065830_2	338963.Pcar_1080	2.88e-82	246.0	COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,42SSF@68525|delta/epsilon subdivisions,2WPME@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_46837_1	1382359.JIAL01000001_gene2776	5.18e-68	215.0	COG3467@1|root,COG3467@2|Bacteria,3Y4HI@57723|Acidobacteria,2JMS6@204432|Acidobacteriia	204432|Acidobacteriia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
k59_243228_1	177437.HRM2_30650	5.23e-48	165.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2MIPC@213118|Desulfobacterales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
k59_438921_2	1198232.CYCME_2291	1.87e-37	137.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria,4603X@72273|Thiotrichales	72273|Thiotrichales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
k59_712908_1	1187848.AJYQ01000003_gene410	2.85e-92	284.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGA@1236|Gammaproteobacteria,1XXNF@135623|Vibrionales	135623|Vibrionales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_40166_1	754252.PFREUD_15260	8.34e-37	142.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4DN4J@85009|Propionibacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_980627_1	96561.Dole_1861	1.07e-109	326.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_79463_1	1149133.ppKF707_1120	1.08e-06	54.3	COG0760@1|root,COG0760@2|Bacteria,1QEVH@1224|Proteobacteria,1TBSA@1236|Gammaproteobacteria,1YIT7@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	SurA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3
k59_1286_1	1121875.KB907546_gene2199	2.35e-63	210.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1I2RR@117743|Flavobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_902278_2	1122137.AQXF01000007_gene3497	9.41e-12	67.0	COG0845@1|root,COG0845@2|Bacteria,1NGI2@1224|Proteobacteria,2U1S9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_510417_1	429009.Adeg_2043	1.88e-42	152.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia,42EQ3@68295|Thermoanaerobacterales	186801|Clostridia	N	PFAM Flagellar motor switch protein FliG	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
k59_1098253_1	1266925.JHVX01000013_gene1653	5.46e-48	164.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2VHF0@28216|Betaproteobacteria,373YA@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
k59_1098253_2	368407.Memar_2035	1.9e-48	162.0	COG0778@1|root,arCOG00288@2157|Archaea,2XXW2@28890|Euryarchaeota,2N9TG@224756|Methanomicrobia	224756|Methanomicrobia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
k59_784749_1	1121405.dsmv_1591	9.18e-31	117.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2MIF1@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
k59_784749_2	96561.Dole_2076	8.95e-32	115.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2WNCZ@28221|Deltaproteobacteria,2MJXP@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
k59_157837_1	439235.Dalk_1786	8.02e-32	117.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2MIR6@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
k59_863180_1	1424334.W822_18500	2.14e-59	208.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,3T558@506|Alcaligenaceae	28216|Betaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_1058999_1	247490.KSU1_D0121	1.09e-81	255.0	COG0538@1|root,COG0538@2|Bacteria,2J51C@203682|Planctomycetes	203682|Planctomycetes	C	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
k59_1019849_1	1120792.JAFV01000001_gene187	1.1e-44	152.0	COG1802@1|root,COG1802@2|Bacteria,1MXNF@1224|Proteobacteria,2U1PK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_1137460_1	1161401.ASJA01000004_gene2307	4.68e-77	244.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2TRD1@28211|Alphaproteobacteria,43XDX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Membrane bound O-acyl transferase family	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
k59_82832_2	1458275.AZ34_10180	1.02e-06	50.4	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,4AABT@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
k59_1140279_1	1232437.KL662020_gene705	2.57e-58	194.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_43288_1	1002340.AFCF01000052_gene1570	9.66e-24	104.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	N-methylhydantoinase B acetone carboxylase alpha subunit	MA20_04180	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
k59_944650_1	1122604.JONR01000007_gene2905	9.26e-42	145.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,1S92R@1236|Gammaproteobacteria,1XC0I@135614|Xanthomonadales	135614|Xanthomonadales	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
k59_552749_1	1198232.CYCME_0743	3.69e-148	425.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,45ZSW@72273|Thiotrichales	72273|Thiotrichales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_121903_1	933262.AXAM01000023_gene663	1.65e-47	168.0	COG0079@1|root,COG0283@1|root,COG0079@2|Bacteria,COG0283@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2MIX3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_670337_1	1134474.O59_000465	2.03e-35	134.0	28P4Q@1|root,2ZBZV@2|Bacteria,1RA48@1224|Proteobacteria,1S347@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_709247_1	391587.KAOT1_17583	2.14e-09	61.2	COG1595@1|root,COG1595@2|Bacteria,4NNWH@976|Bacteroidetes,1I2FC@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_121925_1	1479239.JQMU01000001_gene1105	3.65e-18	82.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U59A@28211|Alphaproteobacteria,2K0G8@204457|Sphingomonadales	204457|Sphingomonadales	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_121925_2	1121920.AUAU01000023_gene2400	2.62e-45	161.0	COG0471@1|root,COG0471@2|Bacteria,3Y6TC@57723|Acidobacteria	57723|Acidobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
k59_278467_1	56780.SYN_01404	3.75e-51	184.0	COG2203@1|root,COG2804@1|root,COG2203@2|Bacteria,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,T2SSE,T2SSE_N
k59_1180005_1	694427.Palpr_2637	2.83e-19	91.3	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,4NKE3@976|Bacteroidetes,2FNTG@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA
k59_905330_1	94624.Bpet2232	2.17e-37	143.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2VJN4@28216|Betaproteobacteria,3T30K@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_905335_1	335543.Sfum_1278	4.02e-65	217.0	COG0427@1|root,COG0454@1|root,COG0427@2|Bacteria,COG0456@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MR2F@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	acetyl-CoA	-	-	-	ko:K18122,ko:K18288	ko00650,ko00660,ko01100,ko01200,map00650,map00660,map01100,map01200	-	R02407,R05336,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2142,iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
k59_709290_1	1121405.dsmv_1537	1.02e-52	182.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,42M2C@68525|delta/epsilon subdivisions,2WIVE@28221|Deltaproteobacteria,2MJD6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
k59_4459_1	765911.Thivi_3691	6.67e-32	127.0	COG0642@1|root,COG1225@1|root,COG1225@2|Bacteria,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria,1WXM4@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_709297_1	1394178.AWOO02000001_gene1278	9.53e-25	107.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4EID2@85012|Streptosporangiales	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_161153_1	350688.Clos_0569	8.5e-56	184.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia,36HJU@31979|Clostridiaceae	186801|Clostridia	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
k59_1218833_1	1121405.dsmv_0270	3.69e-66	210.0	COG3385@1|root,COG3385@2|Bacteria,1NBHF@1224|Proteobacteria,43BBP@68525|delta/epsilon subdivisions,2WRX0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_1101408_1	435908.IDSA_11790	2.53e-12	72.4	COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,1RR5H@1236|Gammaproteobacteria,2QFX8@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	PDZ,PDZ_2,Peptidase_S41
k59_82959_2	1535422.ND16A_1372	1e-36	135.0	2DNBN@1|root,32WN2@2|Bacteria,1N5BF@1224|Proteobacteria,1S7CH@1236|Gammaproteobacteria,2Q7BI@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
k59_513925_1	384765.SIAM614_20725	1.83e-20	93.6	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_122021_1	1129794.C427_0217	4.33e-33	124.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,1RR3K@1236|Gammaproteobacteria,469GM@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Domain related to MnhB subunit of Na+/H+ antiporter	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB
k59_122021_2	876044.IMCC3088_2038	1.84e-08	53.5	COG1320@1|root,COG1320@2|Bacteria	2|Bacteria	P	monovalent cation:proton antiporter activity	mnhG	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
k59_1140367_1	768671.ThimaDRAFT_3082	6.46e-91	281.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1WVX9@135613|Chromatiales	135613|Chromatiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
k59_1140367_2	1035195.HMPREF9997_00163	5.4e-06	51.2	COG1826@1|root,COG1826@2|Bacteria,2HJ5I@201174|Actinobacteria,22NI9@1653|Corynebacteriaceae	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_1140367_3	697282.Mettu_1669	5.62e-11	59.7	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1XFSS@135618|Methylococcales	135618|Methylococcales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
k59_1180081_2	160492.XF_0028	3.83e-05	49.7	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,1X7IT@135614|Xanthomonadales	135614|Xanthomonadales	NU	Prepilin	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
k59_709325_1	519989.ECTPHS_00230	5.11e-86	258.0	COG0209@1|root,COG0209@2|Bacteria,1P4EH@1224|Proteobacteria,1RP1A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	COG0209 Ribonucleotide reductase, alpha subunit	nrdJb	-	-	-	-	-	-	-	-	-	-	-	-
k59_788004_1	565045.NOR51B_114	3.19e-21	95.1	COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,TPR_16,TPR_8
k59_788004_2	1122603.ATVI01000008_gene2274	0.000208	42.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,1SA21@1236|Gammaproteobacteria,1XB6R@135614|Xanthomonadales	135614|Xanthomonadales	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
k59_43408_1	1385517.N800_10640	1.34e-16	88.2	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S5TW@1236|Gammaproteobacteria,1X5PU@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,Trans_reg_C
k59_200196_1	177437.HRM2_20940	1.25e-93	293.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,42MEV@68525|delta/epsilon subdivisions,2WK2S@28221|Deltaproteobacteria,2MIMQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
k59_278558_1	386456.JQKN01000008_gene1541	3.32e-49	170.0	COG1808@1|root,arCOG02264@2157|Archaea,2XTS3@28890|Euryarchaeota,23PVE@183925|Methanobacteria	28890|Euryarchaeota	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
k59_748685_1	128390.XP_009465593.1	9.82e-63	192.0	KOG0114@1|root,KOG0114@2759|Eukaryota,3A2RK@33154|Opisthokonta,3BQBW@33208|Metazoa,3D79E@33213|Bilateria,48EAA@7711|Chordata,49B4Z@7742|Vertebrata,4GUQZ@8782|Aves	33208|Metazoa	A	Splicing factor 3B subunit 6	SF3B6	GO:0000375,GO:0000377,GO:0000398,GO:0001701,GO:0001824,GO:0001825,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005684,GO:0005686,GO:0005689,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008380,GO:0009653,GO:0009790,GO:0009792,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0030532,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0034641,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0048646,GO:0048856,GO:0070013,GO:0071011,GO:0071013,GO:0071704,GO:0090304,GO:0097159,GO:0097525,GO:0120114,GO:1901360,GO:1901363,GO:1902494,GO:1990904	-	ko:K12833	ko03040,map03040	M00352	-	-	ko00000,ko00001,ko00002,ko03041	-	-	-	RRM_1
k59_200204_1	1499967.BAYZ01000074_gene2123	4.07e-101	307.0	COG0438@1|root,COG0438@2|Bacteria,2NQHY@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Glycos_transf_2
k59_4522_4	9541.XP_005595130.1	4.6e-07	53.1	2C1NJ@1|root,2S2Q2@2759|Eukaryota,3A3DS@33154|Opisthokonta,3BS83@33208|Metazoa,3D7UJ@33213|Bilateria,48ESN@7711|Chordata,49BMT@7742|Vertebrata,3JH1Y@40674|Mammalia,35QT2@314146|Euarchontoglires,4MRFY@9443|Primates,36AN1@314294|Cercopithecoidea	33208|Metazoa	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	ND6	GO:0000302,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008150,GO:0009410,GO:0009636,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010257,GO:0014070,GO:0016020,GO:0016043,GO:0019866,GO:0022607,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032981,GO:0033108,GO:0034622,GO:0035094,GO:0042220,GO:0042221,GO:0042493,GO:0042542,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043279,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0060359,GO:0065003,GO:0071840,GO:0072347,GO:1901698,GO:1901700	1.6.5.3	ko:K03884	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q3
k59_1218915_1	1123401.JHYQ01000002_gene2709	3.58e-88	270.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,460SY@72273|Thiotrichales	72273|Thiotrichales	J	PFAM tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
k59_357177_1	1335757.SPICUR_08955	1.25e-75	256.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WX5S@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
k59_239380_1	1190603.AJYD01000067_gene3134	5.4e-29	117.0	COG1988@1|root,COG1988@2|Bacteria,1QK5N@1224|Proteobacteria,1S0MU@1236|Gammaproteobacteria,1XSC2@135623|Vibrionales	135623|Vibrionales	S	membrane-bound metal-dependent hydrolases	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
k59_122093_1	342610.Patl_2993	9.93e-47	171.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,2Q0XA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1101477_1	706587.Desti_1914	2.4e-108	322.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria,2MR3T@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	bamD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k59_905431_1	30611.ENSOGAP00000017004	6.92e-174	486.0	COG0592@1|root,KOG1636@2759|Eukaryota,38MVP@33154|Opisthokonta,3BGUR@33208|Metazoa,3CTAW@33213|Bilateria,4800U@7711|Chordata,48Z1K@7742|Vertebrata,3JFI2@40674|Mammalia,35BGU@314146|Euarchontoglires,4MF3Y@9443|Primates	33208|Metazoa	L	auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand	PCNA	GO:0000003,GO:0000075,GO:0000077,GO:0000082,GO:0000083,GO:0000122,GO:0000226,GO:0000228,GO:0000278,GO:0000302,GO:0000307,GO:0000700,GO:0000701,GO:0000723,GO:0000731,GO:0001101,GO:0001889,GO:0002064,GO:0002065,GO:0002066,GO:0002376,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003690,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005652,GO:0005654,GO:0005657,GO:0005663,GO:0005694,GO:0005813,GO:0005815,GO:0005856,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006275,GO:0006277,GO:0006281,GO:0006282,GO:0006283,GO:0006284,GO:0006287,GO:0006289,GO:0006296,GO:0006297,GO:0006298,GO:0006301,GO:0006355,GO:0006357,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006955,GO:0006959,GO:0006974,GO:0006977,GO:0006979,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007093,GO:0007154,GO:0007165,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007304,GO:0007306,GO:0007307,GO:0007346,GO:0007507,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009059,GO:0009314,GO:0009410,GO:0009411,GO:0009416,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010629,GO:0010927,GO:0010948,GO:0014070,GO:0014823,GO:0015630,GO:0016043,GO:0016070,GO:0016567,GO:0016604,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019104,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0019985,GO:0022402,GO:0022412,GO:0022414,GO:0022607,GO:0022616,GO:0023052,GO:0030154,GO:0030234,GO:0030330,GO:0030331,GO:0030337,GO:0030703,GO:0030707,GO:0030855,GO:0030894,GO:0030971,GO:0030983,GO:0031099,GO:0031100,GO:0031297,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031570,GO:0031571,GO:0031667,GO:0031960,GO:0031974,GO:0031981,GO:0032069,GO:0032070,GO:0032075,GO:0032077,GO:0032135,GO:0032139,GO:0032200,GO:0032201,GO:0032355,GO:0032404,GO:0032405,GO:0032446,GO:0032501,GO:0032502,GO:0032504,GO:0032989,GO:0032991,GO:0032993,GO:0033260,GO:0033554,GO:0033683,GO:0033993,GO:0034399,GO:0034599,GO:0034614,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0035035,GO:0035257,GO:0035258,GO:0035556,GO:0035690,GO:0036211,GO:0042221,GO:0042276,GO:0042493,GO:0042542,GO:0042592,GO:0042698,GO:0042769,GO:0042770,GO:0042802,GO:0043085,GO:0043170,GO:0043200,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043596,GO:0043626,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044773,GO:0044774,GO:0044783,GO:0044786,GO:0044796,GO:0044819,GO:0044843,GO:0044849,GO:0044877,GO:0045005,GO:0045739,GO:0045740,GO:0045786,GO:0045787,GO:0045892,GO:0045930,GO:0045934,GO:0045935,GO:0046483,GO:0046677,GO:0046686,GO:0048468,GO:0048477,GO:0048511,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051276,GO:0051336,GO:0051345,GO:0051384,GO:0051427,GO:0051606,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0060249,GO:0060255,GO:0060429,GO:0061008,GO:0061695,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070182,GO:0070206,GO:0070207,GO:0070301,GO:0070557,GO:0070647,GO:0070887,GO:0070987,GO:0071156,GO:0071158,GO:0071214,GO:0071236,GO:0071466,GO:0071478,GO:0071482,GO:0071548,GO:0071704,GO:0071840,GO:0071897,GO:0072331,GO:0072359,GO:0072395,GO:0072401,GO:0072413,GO:0072422,GO:0072431,GO:0080090,GO:0080134,GO:0080135,GO:0090068,GO:0090304,GO:0090305,GO:0097159,GO:0097237,GO:0097327,GO:0097421,GO:0098772,GO:0104004,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901654,GO:1901698,GO:1901700,GO:1901701,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902065,GO:1902400,GO:1902402,GO:1902403,GO:1902494,GO:1902554,GO:1902679,GO:1902806,GO:1902807,GO:1902850,GO:1902911,GO:1902990,GO:1903047,GO:1903506,GO:1903507,GO:1990234,GO:1990782,GO:2000045,GO:2000112,GO:2000113,GO:2000134,GO:2001020,GO:2001022,GO:2001141	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
k59_513988_1	331869.BAL199_10310	2.71e-60	196.0	COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,2TU3Y@28211|Alphaproteobacteria,4BQ6H@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
k59_357210_1	706587.Desti_5255	8.15e-106	339.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2MR5Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_905443_1	1265313.HRUBRA_02214	3.78e-57	181.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1J67K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
k59_905443_2	314282.PCNPT3_09180	3.41e-37	125.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,2QJ6G@267894|Psychromonadaceae	1236|Gammaproteobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_161269_1	648996.Theam_1116	7.94e-39	149.0	COG0068@1|root,COG0068@2|Bacteria,2G3JK@200783|Aquificae	200783|Aquificae	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_514005_1	1232437.KL661966_gene3140	9.35e-71	236.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MHW3@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1023459_1	330214.NIDE4145	2.6e-54	182.0	COG1004@1|root,COG1004@2|Bacteria,3J0EJ@40117|Nitrospirae	40117|Nitrospirae	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
k59_161279_1	768066.HELO_4445	4.3e-81	250.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1XHVC@135619|Oceanospirillales	135619|Oceanospirillales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_984304_1	1454004.AW11_00535	1.54e-62	209.0	COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,2VKTF@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
k59_827280_1	1123504.JQKD01000042_gene4683	5.04e-09	55.5	COG3126@1|root,COG3126@2|Bacteria,1N8AF@1224|Proteobacteria,2VXB0@28216|Betaproteobacteria,4AFNN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	MliC,YscW
k59_827280_2	1232437.KL661986_gene3644	1.24e-48	161.0	COG5608@1|root,COG5608@2|Bacteria,1MZF0@1224|Proteobacteria,42UYQ@68525|delta/epsilon subdivisions,2WQH5@28221|Deltaproteobacteria,2MKS6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Water Stress and Hypersensitive response	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
k59_200286_1	118797.XP_007454293.1	1.88e-117	339.0	COG5040@1|root,KOG0841@2759|Eukaryota,38CKG@33154|Opisthokonta,3BCFK@33208|Metazoa,3CT6T@33213|Bilateria,486HK@7711|Chordata,496RR@7742|Vertebrata,3J7UW@40674|Mammalia,4IY18@91561|Cetartiodactyla	33208|Metazoa	O	Tyrosine 3-monooxygenase tryptophan 5-monooxygenase activation protein epsilon	YWHAE	GO:0000003,GO:0000075,GO:0000077,GO:0000086,GO:0000165,GO:0000226,GO:0000278,GO:0000902,GO:0000904,GO:0001508,GO:0001709,GO:0001764,GO:0001932,GO:0001933,GO:0002027,GO:0003002,GO:0003006,GO:0003062,GO:0003064,GO:0003674,GO:0004857,GO:0004860,GO:0005085,GO:0005088,GO:0005246,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005871,GO:0005875,GO:0006464,GO:0006468,GO:0006469,GO:0006605,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006839,GO:0006873,GO:0006874,GO:0006875,GO:0006886,GO:0006928,GO:0006935,GO:0006950,GO:0006974,GO:0006996,GO:0007005,GO:0007006,GO:0007010,GO:0007017,GO:0007049,GO:0007088,GO:0007093,GO:0007154,GO:0007163,GO:0007165,GO:0007275,GO:0007276,GO:0007280,GO:0007281,GO:0007292,GO:0007293,GO:0007294,GO:0007308,GO:0007309,GO:0007346,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007417,GO:0007420,GO:0007444,GO:0007447,GO:0007450,GO:0007568,GO:0008016,GO:0008103,GO:0008104,GO:0008150,GO:0008152,GO:0008340,GO:0008354,GO:0008426,GO:0009266,GO:0009314,GO:0009408,GO:0009411,GO:0009416,GO:0009605,GO:0009628,GO:0009653,GO:0009798,GO:0009888,GO:0009892,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0009994,GO:0010259,GO:0010389,GO:0010466,GO:0010563,GO:0010564,GO:0010605,GO:0010638,GO:0010646,GO:0010647,GO:0010821,GO:0010822,GO:0010941,GO:0010942,GO:0010951,GO:0010959,GO:0015031,GO:0015459,GO:0015630,GO:0015833,GO:0016043,GO:0016247,GO:0016310,GO:0016325,GO:0016477,GO:0017016,GO:0017112,GO:0017137,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019538,GO:0019725,GO:0019887,GO:0019899,GO:0019904,GO:0019953,GO:0021537,GO:0021543,GO:0021700,GO:0021761,GO:0021766,GO:0021987,GO:0022008,GO:0022402,GO:0022406,GO:0022412,GO:0022414,GO:0022607,GO:0022898,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0030003,GO:0030030,GO:0030031,GO:0030154,GO:0030162,GO:0030182,GO:0030234,GO:0030291,GO:0030424,GO:0030426,GO:0030427,GO:0030706,GO:0030716,GO:0030900,GO:0030951,GO:0030952,GO:0031175,GO:0031267,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031570,GO:0031625,GO:0032268,GO:0032269,GO:0032386,GO:0032388,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032880,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033157,GO:0033267,GO:0033554,GO:0033673,GO:0034220,GO:0034605,GO:0034613,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0035220,GO:0035222,GO:0035295,GO:0035303,GO:0035304,GO:0035305,GO:0035308,GO:0035329,GO:0035556,GO:0035637,GO:0036211,GO:0040008,GO:0040011,GO:0042221,GO:0042325,GO:0042326,GO:0042330,GO:0042391,GO:0042592,GO:0042802,GO:0042826,GO:0042886,GO:0042981,GO:0042995,GO:0043005,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043086,GO:0043154,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043266,GO:0043269,GO:0043271,GO:0043281,GO:0043412,GO:0043549,GO:0044057,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044325,GO:0044389,GO:0044421,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0044877,GO:0045165,GO:0045171,GO:0045172,GO:0045184,GO:0045309,GO:0045786,GO:0045859,GO:0045861,GO:0045927,GO:0045930,GO:0045936,GO:0046822,GO:0046824,GO:0046825,GO:0046827,GO:0046902,GO:0046907,GO:0046982,GO:0046983,GO:0048190,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048599,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050815,GO:0050896,GO:0051020,GO:0051049,GO:0051050,GO:0051051,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051219,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051248,GO:0051336,GO:0051338,GO:0051346,GO:0051348,GO:0051480,GO:0051640,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051924,GO:0051926,GO:0052547,GO:0052548,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0060255,GO:0060271,GO:0060306,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061024,GO:0061337,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070727,GO:0070925,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071900,GO:0071901,GO:0072503,GO:0072507,GO:0080090,GO:0080134,GO:0080135,GO:0086001,GO:0086009,GO:0086011,GO:0086013,GO:0086091,GO:0090087,GO:0090316,GO:0090559,GO:0090723,GO:0090724,GO:0097110,GO:0097458,GO:0097485,GO:0097711,GO:0098771,GO:0098772,GO:0099106,GO:0099622,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0120039,GO:0140056,GO:0150034,GO:1900034,GO:1900739,GO:1900740,GO:1901016,GO:1901019,GO:1901020,GO:1901028,GO:1901030,GO:1901379,GO:1901564,GO:1901987,GO:1901990,GO:1902308,GO:1902309,GO:1902749,GO:1903047,GO:1903169,GO:1903170,GO:1903522,GO:1903747,GO:1903749,GO:1903827,GO:1903829,GO:1904062,GO:1904063,GO:1904951,GO:1905475,GO:1905477,GO:1905912,GO:1905913,GO:2000116,GO:2000117,GO:2001233,GO:2001235	-	ko:K06630	ko04011,ko04110,ko04114,ko04151,ko04390,ko04391,ko04722,ko05169,ko05203,map04011,map04110,map04114,map04151,map04390,map04391,map04722,map05169,map05203	-	-	-	ko00000,ko00001,ko03400,ko04147	-	-	-	14-3-3
k59_421637_2	1121405.dsmv_1427	3.51e-13	68.2	COG2836@1|root,COG2836@2|Bacteria,1PJER@1224|Proteobacteria,43EBU@68525|delta/epsilon subdivisions,2X2D4@28221|Deltaproteobacteria,2MMFS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_1123128_2	857087.Metme_2089	1.09e-08	57.8	COG3637@1|root,COG3637@2|Bacteria,1R64D@1224|Proteobacteria,1S325@1236|Gammaproteobacteria,1XDN4@135618|Methylococcales	135618|Methylococcales	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
k59_105753_1	909663.KI867149_gene3450	8.65e-08	56.2	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2MQC3@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_105753_2	452637.Oter_3626	3.78e-21	91.7	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,46SM2@74201|Verrucomicrobia,3K9SZ@414999|Opitutae	414999|Opitutae	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_379324_1	768671.ThimaDRAFT_0623	1.14e-14	73.2	2AE9B@1|root,3143E@2|Bacteria,1QXVV@1224|Proteobacteria,1TK9T@1236|Gammaproteobacteria,1X0TV@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_379324_2	246200.SPO0301	4.85e-20	90.5	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2UDP0@28211|Alphaproteobacteria,4NBKE@97050|Ruegeria	28211|Alphaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
k59_538453_1	998674.ATTE01000001_gene3554	1.6e-65	214.0	COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,1RYAY@1236|Gammaproteobacteria,4602F@72273|Thiotrichales	72273|Thiotrichales	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
k59_300830_1	251221.35210611	1.61e-27	113.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	iYO844.BSU02760	ABC2_membrane_2,ABC2_membrane_3
k59_224464_1	1129794.C427_2463	2.28e-52	175.0	COG4123@1|root,COG4123@2|Bacteria,1QZ7Z@1224|Proteobacteria,1T419@1236|Gammaproteobacteria,46D8Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
k59_887989_1	565045.NOR51B_122	1.47e-102	308.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RQ0P@1236|Gammaproteobacteria,1JA4R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
k59_887989_2	1121374.KB891575_gene797	1.81e-35	132.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RSGI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1233 Phytoene dehydrogenase and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
k59_339483_1	1397528.Q671_16165	2.85e-161	474.0	COG3243@1|root,COG3243@2|Bacteria,1MUNE@1224|Proteobacteria,1RNZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Protein of unknown function (DUF3141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3141
k59_1123154_1	443152.MDG893_08190	7.73e-46	167.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,464S3@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_496196_1	266265.Bxe_C0490	1.67e-72	235.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2VWYN@28216|Betaproteobacteria,1K8UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	Transposase_20
k59_1010984_1	1122603.ATVI01000005_gene3498	4.32e-21	100.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SZ6C@1236|Gammaproteobacteria,1XCCV@135614|Xanthomonadales	1236|Gammaproteobacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_19,TPR_2,TPR_8
k59_730999_1	768671.ThimaDRAFT_2229	3.91e-86	283.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG4770@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,COG4770@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1WX8J@135613|Chromatiales	135613|Chromatiales	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
k59_1123157_1	713586.KB900536_gene292	2.14e-51	172.0	COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,1RQ41@1236|Gammaproteobacteria,1WXEC@135613|Chromatiales	135613|Chromatiales	S	subfamily IA, variant 1	-	-	3.1.3.102,3.1.3.104	ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
k59_1083011_1	1150626.PHAMO_80087	4.13e-14	79.7	COG3941@1|root,COG3941@2|Bacteria,1PHQP@1224|Proteobacteria,2V9RW@28211|Alphaproteobacteria,2JWSI@204441|Rhodospirillales	204441|Rhodospirillales	S	Lambda phage tail tape-measure protein (Tape_meas_lam_C)	-	-	-	-	-	-	-	-	-	-	-	-	Tape_meas_lam_C
k59_1046598_1	228405.HNE_2123	1.21e-32	124.0	COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,2TS7P@28211|Alphaproteobacteria,43XPB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Allophanate hydrolase subunit 2	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	CT_A_B
k59_1046598_2	1123284.KB899046_gene2291	9.89e-16	75.9	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,4HHJJ@91061|Bacilli,26PRE@186821|Sporolactobacillaceae	91061|Bacilli	E	Allophanate hydrolase subunit 1	kipI	-	-	ko:K06351	-	-	-	-	ko00000	-	-	-	CT_C_D
k59_888019_1	742817.HMPREF9449_01268	9.47e-69	213.0	COG2110@1|root,COG2110@2|Bacteria,4NNRH@976|Bacteroidetes,2FMVR@200643|Bacteroidia,22Y29@171551|Porphyromonadaceae	976|Bacteroidetes	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
k59_574340_1	595460.RRSWK_04192	9.43e-101	313.0	COG0296@1|root,COG0296@2|Bacteria,2IXS1@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_925965_1	296591.Bpro_4364	3.05e-20	94.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VP9T@28216|Betaproteobacteria,4ACDH@80864|Comamonadaceae	28216|Betaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_925965_2	1211115.ALIQ01000171_gene4105	7.62e-08	52.0	COG2164@1|root,COG2164@2|Bacteria,1RCY5@1224|Proteobacteria,2U5NN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3830)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3830
k59_25422_1	61853.ENSNLEP00000006906	2.72e-81	241.0	2C82A@1|root,2S8GM@2759|Eukaryota,3A5Z9@33154|Opisthokonta,3BSHW@33208|Metazoa,3D8P4@33213|Bilateria,48F73@7711|Chordata,49C8W@7742|Vertebrata,3JHEH@40674|Mammalia,35QM6@314146|Euarchontoglires,4MJSS@9443|Primates	33208|Metazoa	T	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	B2M	GO:0000041,GO:0000139,GO:0001775,GO:0001817,GO:0001819,GO:0001910,GO:0001912,GO:0001914,GO:0001916,GO:0002237,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002428,GO:0002443,GO:0002444,GO:0002446,GO:0002474,GO:0002475,GO:0002477,GO:0002478,GO:0002479,GO:0002480,GO:0002481,GO:0002483,GO:0002520,GO:0002521,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002703,GO:0002705,GO:0002706,GO:0002708,GO:0002709,GO:0002711,GO:0002718,GO:0002720,GO:0002724,GO:0002726,GO:0002819,GO:0002821,GO:0002822,GO:0002824,GO:0003254,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005783,GO:0005788,GO:0005794,GO:0005798,GO:0005829,GO:0005886,GO:0006457,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006887,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006968,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007399,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009897,GO:0009986,GO:0009987,GO:0010008,GO:0010033,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0010721,GO:0010959,GO:0010975,GO:0010977,GO:0012505,GO:0012506,GO:0012507,GO:0015682,GO:0016020,GO:0016032,GO:0016192,GO:0019221,GO:0019538,GO:0019730,GO:0019731,GO:0019882,GO:0019883,GO:0019884,GO:0019885,GO:0022008,GO:0023052,GO:0030001,GO:0030097,GO:0030098,GO:0030100,GO:0030133,GO:0030134,GO:0030135,GO:0030139,GO:0030141,GO:0030154,GO:0030217,GO:0030658,GO:0030659,GO:0030660,GO:0030662,GO:0030666,GO:0030670,GO:0031090,GO:0031341,GO:0031343,GO:0031344,GO:0031345,GO:0031410,GO:0031901,GO:0031904,GO:0031905,GO:0031974,GO:0031982,GO:0031983,GO:0031984,GO:0032091,GO:0032092,GO:0032496,GO:0032501,GO:0032502,GO:0032879,GO:0032940,GO:0032991,GO:0033077,GO:0033216,GO:0033993,GO:0034097,GO:0034341,GO:0034756,GO:0034774,GO:0035580,GO:0036230,GO:0042026,GO:0042110,GO:0042119,GO:0042221,GO:0042391,GO:0042493,GO:0042581,GO:0042590,GO:0042592,GO:0042742,GO:0042802,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043235,GO:0043269,GO:0043299,GO:0043312,GO:0043393,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045055,GO:0045087,GO:0045321,GO:0045335,GO:0045595,GO:0045596,GO:0045637,GO:0045646,GO:0045664,GO:0045665,GO:0045807,GO:0046649,GO:0046686,GO:0046903,GO:0048002,GO:0048259,GO:0048260,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050690,GO:0050767,GO:0050768,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050829,GO:0050830,GO:0050896,GO:0051049,GO:0051050,GO:0051093,GO:0051098,GO:0051099,GO:0051100,GO:0051128,GO:0051129,GO:0051130,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051704,GO:0051707,GO:0051716,GO:0051960,GO:0051961,GO:0055037,GO:0055038,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0060205,GO:0060284,GO:0060333,GO:0060627,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070820,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071241,GO:0071248,GO:0071281,GO:0071283,GO:0071310,GO:0071345,GO:0071346,GO:0071396,GO:0071704,GO:0071944,GO:0072512,GO:0097286,GO:0097708,GO:0098542,GO:0098552,GO:0098588,GO:0098771,GO:0098791,GO:0098796,GO:0098797,GO:0098802,GO:0098805,GO:0099503,GO:0120035,GO:1900120,GO:1900121,GO:1900122,GO:1900390,GO:1901564,GO:1901700,GO:1901701,GO:1903706,GO:1904432,GO:1904434,GO:1904435,GO:1904437,GO:1904724,GO:1990712,GO:2000026	-	ko:K08055	ko04612,map04612	-	-	-	ko00000,ko00001,ko04147	-	-	-	C1-set
k59_224494_1	69328.PVLB_19730	0.000118	44.7	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	ydcT	-	-	ko:K02052,ko:K11076	ko02010,ko02024,map02010,map02024	M00193,M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.2	-	-	ABC_tran,TOBE_2
k59_224494_2	1097668.BYI23_C007430	1.17e-13	72.8	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,1K3GD@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1046607_1	1118235.CAJH01000047_gene2964	1.14e-74	230.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1X2XT@135614|Xanthomonadales	135614|Xanthomonadales	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07660	ko01503,ko02020,map01503,map02020	M00444,M00709,M00721,M00723,M00724,M00744	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_808189_1	641491.DND132_3451	9.07e-50	177.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2M8U3@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
k59_379409_1	314285.KT71_16791	9.5e-153	443.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria,1J7W3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_848672_1	1033730.CAHG01000016_gene350	6.01e-07	55.1	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4DT31@85009|Propionibacteriales	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
k59_1123198_1	247634.GPB2148_827	5.95e-34	128.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria,1JAB2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG3202 ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
k59_1123198_2	1231392.OCGS_2671	1.39e-28	112.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.174,2.3.1.9	ko:K00626,ko:K00632,ko:K07823	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_261658_2	882378.RBRH_01758	2.83e-05	49.7	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,1K38N@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_614026_1	991905.SL003B_4285	3.26e-83	264.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,4BPE4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	yejF	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
k59_538560_1	1145276.T479_13475	6.49e-18	87.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HBB2@91061|Bacilli,3IX2N@400634|Lysinibacillus	91061|Bacilli	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	iYO844.BSU14520	Adenine_deam_C,Amidohydro_1
k59_538560_2	1265505.ATUG01000001_gene4051	4.11e-30	112.0	COG0745@1|root,COG0745@2|Bacteria,1NRN6@1224|Proteobacteria,42YX2@68525|delta/epsilon subdivisions,2WUBG@28221|Deltaproteobacteria,2MMZJ@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_423535_1	1230343.CANP01000040_gene3049	3.41e-11	64.7	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1JC6X@118969|Legionellales	118969|Legionellales	L	Arm DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
k59_496272_1	317936.Nos7107_0867	2.81e-07	52.0	COG1054@1|root,COG1054@2|Bacteria,1G0HW@1117|Cyanobacteria,1HIEY@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the UPF0176 family	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
k59_496272_2	1323663.AROI01000003_gene2180	1.55e-21	97.1	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iECs_1301.ECs5024,iG2583_1286.G2583_4866	Acyltransferase
k59_1011056_2	1120956.JHZK01000007_gene2921	5.69e-45	149.0	COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,2U9DZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	rhodanese-related sulfurtransferase	MA20_01310	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_339588_1	243233.MCA2063	1.51e-11	64.3	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1XDQR@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_339588_2	1134474.O59_002035	6.07e-71	219.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,1FFTC@10|Cellvibrio	1236|Gammaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_339602_1	706587.Desti_1016	2.87e-19	85.9	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WMSH@28221|Deltaproteobacteria,2MQBV@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_339602_2	1306406.ASHX01000001_gene823	7.01e-32	122.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria	201174|Actinobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
k59_538619_1	1500890.JQNL01000001_gene189	5.65e-47	165.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,1XAMK@135614|Xanthomonadales	135614|Xanthomonadales	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
k59_1244826_1	926564.KI911615_gene4435	1.87e-15	70.5	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4F4VY@85017|Promicromonosporaceae	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
k59_1244826_2	768710.DesyoDRAFT_0915	2.29e-15	78.6	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_9
k59_64402_1	313606.M23134_04333	6.62e-10	60.1	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_1046701_1	565045.NOR51B_2264	1.51e-33	125.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	von willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
k59_1046701_2	1472418.BBJC01000001_gene265	0.000172	45.8	COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,2U3H3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_11,TPR_2,VWA_2
k59_770294_1	1008457.BAEX01000030_gene2389	6.13e-18	84.7	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,1HYA6@117743|Flavobacteriia,47H0K@76831|Myroides	976|Bacteroidetes	S	Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
k59_692281_1	1123377.AUIV01000003_gene1763	5.91e-67	229.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1X36U@135614|Xanthomonadales	135614|Xanthomonadales	CE	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
k59_1162284_1	411474.COPEUT_02951	4.16e-06	52.8	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
k59_182412_1	1121405.dsmv_2866	2.76e-100	307.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42N16@68525|delta/epsilon subdivisions,2X73Y@28221|Deltaproteobacteria,2MJEF@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	dppA	-	-	ko:K02035,ko:K12368	ko02010,ko02024,ko02030,map02010,map02024,map02030	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_1201825_1	1286093.C266_04989	3.39e-73	227.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2VHEK@28216|Betaproteobacteria,1K21Q@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
k59_848790_1	653733.Selin_2168	4.81e-108	319.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
k59_456908_1	1267005.KB911255_gene3031	3.65e-70	222.0	28W98@1|root,2ZI9R@2|Bacteria,1NQ3G@1224|Proteobacteria,2TT2E@28211|Alphaproteobacteria,3N8E5@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1083163_1	96561.Dole_3185	1.12e-10	61.6	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MHKH@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_423664_1	631362.Thi970DRAFT_03746	1.46e-21	93.2	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria	1224|Proteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_966921_1	1042377.AFPJ01000010_gene1427	4.95e-18	78.6	COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,1SD0G@1236|Gammaproteobacteria,468PW@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
k59_966921_2	506534.Rhein_0884	8.99e-24	95.1	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1S65I@1236|Gammaproteobacteria,1X15T@135613|Chromatiales	135613|Chromatiales	S	MgtC family	-	-	-	-	-	-	-	-	-	-	-	-	MgtC
k59_106031_1	2340.JV46_20400	2.89e-107	325.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1J5MF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NADH ubiquinone oxidoreductase subunit	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
k59_456919_1	1304872.JAGC01000009_gene1025	2.05e-06	51.2	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,42NI3@68525|delta/epsilon subdivisions,2WJ6P@28221|Deltaproteobacteria,2M856@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_456919_2	1068978.AMETH_0144	5.49e-18	81.3	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4E1TV@85010|Pseudonocardiales	201174|Actinobacteria	E	pfam abc	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_1083173_1	1230476.C207_05092	8.44e-98	302.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2TT05@28211|Alphaproteobacteria,3JS8N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
k59_692315_1	1210884.HG799470_gene14561	5.86e-69	226.0	COG3385@1|root,COG3385@2|Bacteria,2J32V@203682|Planctomycetes	203682|Planctomycetes	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_106054_1	1532558.JL39_06540	3.65e-89	276.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,4B6ZF@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_142988_1	9940.ENSOARP00000006790	1.64e-167	473.0	COG1889@1|root,KOG1596@2759|Eukaryota,38EYU@33154|Opisthokonta,3BCKB@33208|Metazoa,3CXRH@33213|Bilateria,480X2@7711|Chordata,48VH0@7742|Vertebrata,3JDNQ@40674|Mammalia,4J72R@91561|Cetartiodactyla	33208|Metazoa	A	Fibrillarin	FBL	GO:0000154,GO:0000494,GO:0001085,GO:0001091,GO:0001094,GO:0001098,GO:0001099,GO:0001510,GO:0001650,GO:0001651,GO:0001652,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005732,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006403,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008134,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0015030,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016604,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0019899,GO:0022613,GO:0030532,GO:0030684,GO:0031123,GO:0031126,GO:0031167,GO:0031428,GO:0031974,GO:0031981,GO:0032040,GO:0032259,GO:0032991,GO:0033036,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044452,GO:0044464,GO:0046483,GO:0048254,GO:0051117,GO:0051179,GO:0051276,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0120114,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259,GO:1990904	-	ko:K14563	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009	-	-	-	Fibrillarin
k59_1011154_1	1122135.KB893167_gene2384	6.08e-23	100.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,2TQXU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
k59_1011154_2	488538.SAR116_0305	3.23e-83	256.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,2U0W7@28211|Alphaproteobacteria,4BR7X@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal domain	-	GO:0000287,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0016597,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043200,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046872,GO:0050896,GO:0051716,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:1901564,GO:1901605,GO:1901698,GO:1901699,GO:1901700,GO:1901701	4.2.1.171	ko:K21624	ko00330,map00330	-	R11625	-	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
k59_1046761_1	9606.ENSP00000421922	5.5e-70	220.0	KOG3956@1|root,KOG3956@2759|Eukaryota,38D63@33154|Opisthokonta,3BG2D@33208|Metazoa,3CT3X@33213|Bilateria,48AMZ@7711|Chordata,4976W@7742|Vertebrata,3J5IZ@40674|Mammalia,35I93@314146|Euarchontoglires,4ME4R@9443|Primates,4N1FB@9604|Hominidae	33208|Metazoa	IOTUV	Alpha-2-macroglobulin RAP, N-terminal domain	LRPAP1	GO:0001540,GO:0002090,GO:0002091,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005783,GO:0005788,GO:0005791,GO:0005793,GO:0005794,GO:0005801,GO:0005886,GO:0006810,GO:0008150,GO:0009892,GO:0009966,GO:0009968,GO:0010469,GO:0010605,GO:0010646,GO:0010648,GO:0010915,GO:0010916,GO:0010941,GO:0010984,GO:0010985,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0019899,GO:0023051,GO:0023057,GO:0030100,GO:0030545,GO:0030547,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0032091,GO:0032879,GO:0033218,GO:0035473,GO:0042277,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0044092,GO:0044422,GO:0044424,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045056,GO:0045806,GO:0048019,GO:0048237,GO:0048259,GO:0048261,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050750,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051098,GO:0051100,GO:0051128,GO:0051129,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0060255,GO:0060548,GO:0060627,GO:0065007,GO:0065009,GO:0070013,GO:0070325,GO:0070326,GO:0071944,GO:0097708,GO:0098772,GO:1900115,GO:1900116,GO:1900221,GO:1900222,GO:1900223,GO:2000272	-	ko:K22290	ko04979,map04979	-	-	-	ko00000,ko00001	-	-	-	Alpha-2-MRAP_C,Alpha-2-MRAP_N
k59_379648_1	1232410.KI421425_gene1544	1.04e-44	150.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,42X3K@68525|delta/epsilon subdivisions,2WT0T@28221|Deltaproteobacteria,43V5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	aglS	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_496398_1	1049564.TevJSym_ab01870	5.93e-35	134.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1J4SM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Permease	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_888224_1	1123073.KB899241_gene1933	1.02e-40	145.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1X3P1@135614|Xanthomonadales	135614|Xanthomonadales	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
k59_1046777_1	1111732.AZOD01000007_gene451	7.66e-98	291.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,1X4J2@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_1123385_1	1121405.dsmv_3389	1.42e-85	256.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,42RXS@68525|delta/epsilon subdivisions,2WNA0@28221|Deltaproteobacteria,2MJTK@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM transcription factor CarD	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
k59_848862_1	406124.ACPC01000019_gene2939	2.53e-13	69.3	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus	91061|Bacilli	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_8,PAS,PAS_9,Sigma54_activat
k59_808392_1	999541.bgla_1g30080	5.83e-15	74.3	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,1K10V@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_808392_2	1454004.AW11_01010	4.22e-27	107.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,1KQYN@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
k59_223303_1	626887.J057_20380	1.92e-62	204.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,464VM@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
k59_1081789_1	1121878.AUGL01000021_gene2815	5.19e-109	332.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_886738_1	583355.Caka_1597	2.76e-52	177.0	COG0668@1|root,COG0668@2|Bacteria,46UFI@74201|Verrucomicrobia,3K8BZ@414999|Opitutae	414999|Opitutae	M	mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_729800_1	1123228.AUIH01000010_gene4002	2.23e-105	317.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,1XPHQ@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_924771_1	697282.Mettu_3552	9.92e-75	231.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1XDV4@135618|Methylococcales	135618|Methylococcales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_63012_1	335543.Sfum_0552	8.72e-38	140.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WKTU@28221|Deltaproteobacteria,2MQRV@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_141596_1	555779.Dthio_PD0652	4.74e-30	125.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJTY@28221|Deltaproteobacteria,2MG38@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
k59_536886_1	233894.Q19CM1_9CAUD	6.25e-16	79.3	4QAZ6@10239|Viruses,4QUU8@35237|dsDNA viruses  no RNA stage,4QPHV@28883|Caudovirales,4QI4H@10662|Myoviridae	10662|Myoviridae	S	Phage tail sheath protein	-	GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098027	-	-	-	-	-	-	-	-	-	-	-
k59_536886_2	444861.E3SPK1_9CAUD	4e-41	152.0	4QHDM@10239|Viruses,4QYV6@35237|dsDNA viruses  no RNA stage,4QRD0@28883|Caudovirales	28883|Caudovirales	S	Terminase-like family	-	GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016032,GO:0016043,GO:0016787,GO:0016788,GO:0019058,GO:0019068,GO:0019069,GO:0019072,GO:0019075,GO:0022607,GO:0032991,GO:0034641,GO:0043170,GO:0043493,GO:0044085,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0046483,GO:0046797,GO:0051704,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0098009,GO:1901360,GO:1902494,GO:1904949	-	-	-	-	-	-	-	-	-	-	-
k59_299653_1	1286171.EAL2_808p03750	3.16e-55	186.0	COG0025@1|root,COG0025@2|Bacteria,1UHUI@1239|Firmicutes,25E2Y@186801|Clostridia	186801|Clostridia	P	Transporter, CPA2 family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_24191_1	639283.Snov_1081	1.16e-17	87.0	28MUE@1|root,2ZB2B@2|Bacteria,1N3YU@1224|Proteobacteria,2TUD9@28211|Alphaproteobacteria,3EZEQ@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
k59_24191_2	1267005.KB911258_gene593	5.29e-76	232.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2TSC9@28211|Alphaproteobacteria,3N6ZA@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
k59_181257_1	9597.XP_003820222.2	6.64e-118	345.0	KOG4005@1|root,KOG4005@2759|Eukaryota,39V81@33154|Opisthokonta,3BHDV@33208|Metazoa,3D2EV@33213|Bilateria,486F9@7711|Chordata,496QI@7742|Vertebrata,3J7BV@40674|Mammalia,35KW6@314146|Euarchontoglires,4MDNA@9443|Primates,4N305@9604|Hominidae	33208|Metazoa	K	basic region leucin zipper	XBP1	GO:0000976,GO:0000977,GO:0001012,GO:0001067,GO:0002119,GO:0002164,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006355,GO:0006357,GO:0006950,GO:0006986,GO:0006990,GO:0007154,GO:0007165,GO:0007275,GO:0008150,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0030968,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032501,GO:0032502,GO:0033554,GO:0034620,GO:0034976,GO:0035966,GO:0035967,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0045944,GO:0046677,GO:0048518,GO:0048522,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0080090,GO:0097159,GO:1901363,GO:1901522,GO:1902680,GO:1903506,GO:1903508,GO:1904576,GO:1990837,GO:2000112,GO:2001141	-	ko:K09027	ko04141,ko04932,ko05166,map04141,map04932,map05166	-	-	-	ko00000,ko00001,ko03000	-	-	-	bZIP_1,bZIP_2
k59_63058_1	706587.Desti_1827	2.46e-132	385.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,42QAD@68525|delta/epsilon subdivisions,2WK5V@28221|Deltaproteobacteria,2MRQ8@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_104217_1	118173.KB235914_gene3293	8.03e-60	201.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1G3MK@1117|Cyanobacteria,1H9X2@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Sporulation stage II, protein E C-terminal	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HAMP,SpoIIE
k59_924829_1	589865.DaAHT2_2294	2.9e-54	180.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WQQK@28221|Deltaproteobacteria,2MPXV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
k59_299680_1	335543.Sfum_2599	5.14e-69	224.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2WIWY@28221|Deltaproteobacteria,2MQAK@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_63074_1	1278078.G419_22149	4.36e-17	78.2	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4G0U1@85025|Nocardiaceae	201174|Actinobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
k59_63074_2	329726.AM1_5362	6.97e-11	65.9	COG0619@1|root,COG0619@2|Bacteria,1G0ZQ@1117|Cyanobacteria	1117|Cyanobacteria	P	ABC-type cobalt transport system permease component CbiQ	cbiQ	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
k59_338259_2	398525.KB900701_gene6821	8.03e-63	202.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2TR4R@28211|Alphaproteobacteria,3JTAE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	MA20_01040	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
k59_63079_1	933262.AXAM01000017_gene3127	2.31e-38	137.0	COG0546@1|root,COG0546@2|Bacteria,1MY9Y@1224|Proteobacteria,42SSC@68525|delta/epsilon subdivisions,2WN7Q@28221|Deltaproteobacteria,2MKDC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
k59_260393_1	1453501.JELR01000001_gene2133	4.34e-47	172.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,463XX@72275|Alteromonadaceae	1236|Gammaproteobacteria	CE	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
k59_1200431_1	880072.Desac_1177	3.75e-40	141.0	COG0794@1|root,COG0794@2|Bacteria,1RAT6@1224|Proteobacteria,4310K@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	COGs COG0794 sugar phosphate isomerase involved in capsule formation	-	-	5.3.1.27	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05339,R09780	RC00377	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS
k59_1200431_2	247490.KSU1_C0309	2.67e-09	57.4	COG0269@1|root,COG0684@1|root,COG0269@2|Bacteria,COG0684@2|Bacteria,2J0G2@203682|Planctomycetes	203682|Planctomycetes	G	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.2.43	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338	RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,RraA-like
k59_1121969_1	1267005.KB911256_gene1967	1.28e-25	109.0	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,2TQZ1@28211|Alphaproteobacteria,3N6UQ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	NU	Bacterial protein of unknown function (DUF882)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
k59_24279_1	1041147.AUFB01000022_gene5339	0.000369	48.1	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_16,TPR_19,TPR_2,TPR_8
k59_651033_1	706587.Desti_2669	2.55e-115	342.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2MQS4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	dsrP	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_181337_1	1038862.KB893806_gene3004	1.22e-45	161.0	COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3JVEX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
k59_651047_1	56780.SYN_01723	3.29e-85	277.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2MQAI@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_1161042_1	9597.XP_003813751.1	1.69e-111	340.0	KOG0575@1|root,KOG0575@2759|Eukaryota,38G8G@33154|Opisthokonta,3BBT5@33208|Metazoa,3D04F@33213|Bilateria,483MI@7711|Chordata,4927Q@7742|Vertebrata,3J83W@40674|Mammalia,35A9C@314146|Euarchontoglires,4MA8I@9443|Primates,4N1QA@9604|Hominidae	33208|Metazoa	D	Protein kinase domain	PLK1	GO:0000003,GO:0000070,GO:0000075,GO:0000077,GO:0000079,GO:0000086,GO:0000122,GO:0000166,GO:0000212,GO:0000226,GO:0000228,GO:0000278,GO:0000280,GO:0000281,GO:0000287,GO:0000741,GO:0000775,GO:0000776,GO:0000777,GO:0000778,GO:0000779,GO:0000780,GO:0000785,GO:0000793,GO:0000794,GO:0000795,GO:0000819,GO:0000910,GO:0000912,GO:0000915,GO:0000922,GO:0000940,GO:0000942,GO:0001578,GO:0001932,GO:0001933,GO:0001934,GO:0003006,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005694,GO:0005737,GO:0005813,GO:0005814,GO:0005815,GO:0005819,GO:0005828,GO:0005829,GO:0005856,GO:0005874,GO:0005876,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006469,GO:0006508,GO:0006511,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006950,GO:0006974,GO:0006996,GO:0006997,GO:0006998,GO:0007010,GO:0007017,GO:0007020,GO:0007049,GO:0007051,GO:0007056,GO:0007058,GO:0007059,GO:0007062,GO:0007077,GO:0007080,GO:0007088,GO:0007093,GO:0007094,GO:0007097,GO:0007098,GO:0007112,GO:0007127,GO:0007135,GO:0007140,GO:0007143,GO:0007147,GO:0007154,GO:0007165,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007292,GO:0007338,GO:0007344,GO:0007346,GO:0007399,GO:0007406,GO:0007507,GO:0008017,GO:0008092,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008283,GO:0008285,GO:0008608,GO:0009056,GO:0009057,GO:0009566,GO:0009790,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0009994,GO:0010256,GO:0010389,GO:0010468,GO:0010498,GO:0010556,GO:0010558,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010629,GO:0010639,GO:0010721,GO:0010799,GO:0010800,GO:0010941,GO:0010948,GO:0010965,GO:0010997,GO:0012505,GO:0015630,GO:0015631,GO:0016043,GO:0016301,GO:0016310,GO:0016321,GO:0016567,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0019941,GO:0019953,GO:0022008,GO:0022402,GO:0022406,GO:0022411,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030029,GO:0030030,GO:0030031,GO:0030036,GO:0030071,GO:0030154,GO:0030162,GO:0030163,GO:0030397,GO:0030496,GO:0030554,GO:0030725,GO:0030726,GO:0030865,GO:0030866,GO:0030953,GO:0030954,GO:0031023,GO:0031032,GO:0031109,GO:0031122,GO:0031145,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031329,GO:0031331,GO:0031396,GO:0031398,GO:0031399,GO:0031400,GO:0031401,GO:0031570,GO:0031572,GO:0031577,GO:0031647,GO:0031648,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032268,GO:0032269,GO:0032270,GO:0032434,GO:0032436,GO:0032446,GO:0032465,GO:0032501,GO:0032502,GO:0032504,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032886,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033046,GO:0033047,GO:0033048,GO:0033206,GO:0033365,GO:0033554,GO:0033673,GO:0034451,GO:0034502,GO:0034504,GO:0034613,GO:0034622,GO:0035044,GO:0035046,GO:0035050,GO:0035295,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0040038,GO:0042127,GO:0042176,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042770,GO:0042802,GO:0042981,GO:0043062,GO:0043063,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043086,GO:0043161,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043393,GO:0043412,GO:0043549,GO:0043632,GO:0043933,GO:0044085,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044454,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044782,GO:0044837,GO:0044839,GO:0044877,GO:0045132,GO:0045143,GO:0045165,GO:0045184,GO:0045595,GO:0045596,GO:0045732,GO:0045736,GO:0045786,GO:0045839,GO:0045841,GO:0045859,GO:0045862,GO:0045892,GO:0045930,GO:0045934,GO:0045936,GO:0045937,GO:0046677,GO:0046785,GO:0046872,GO:0046907,GO:0048232,GO:0048284,GO:0048285,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048568,GO:0048600,GO:0048609,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050000,GO:0050767,GO:0050768,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051081,GO:0051093,GO:0051098,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051225,GO:0051233,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0051255,GO:0051257,GO:0051258,GO:0051276,GO:0051301,GO:0051302,GO:0051303,GO:0051310,GO:0051315,GO:0051321,GO:0051338,GO:0051347,GO:0051348,GO:0051418,GO:0051438,GO:0051443,GO:0051493,GO:0051603,GO:0051640,GO:0051641,GO:0051647,GO:0051649,GO:0051656,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0051960,GO:0051961,GO:0051983,GO:0051985,GO:0060236,GO:0060255,GO:0060271,GO:0060284,GO:0060341,GO:0060429,GO:0060548,GO:0061024,GO:0061136,GO:0061640,GO:0061982,GO:0061983,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070193,GO:0070194,GO:0070507,GO:0070647,GO:0070727,GO:0070925,GO:0071168,GO:0071173,GO:0071174,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0072091,GO:0072359,GO:0072395,GO:0072401,GO:0072422,GO:0072425,GO:0072686,GO:0080090,GO:0090169,GO:0090224,GO:0090306,GO:0090435,GO:0097159,GO:0097367,GO:0097435,GO:0097711,GO:0098687,GO:0098813,GO:0099080,GO:0099081,GO:0099086,GO:0099512,GO:0099513,GO:0120031,GO:0120036,GO:0140013,GO:0140014,GO:0140056,GO:0140096,GO:1900180,GO:1900182,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901673,GO:1901800,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902099,GO:1902100,GO:1902115,GO:1902679,GO:1902692,GO:1902749,GO:1902750,GO:1903046,GO:1903047,GO:1903050,GO:1903052,GO:1903320,GO:1903322,GO:1903362,GO:1903364,GO:1903506,GO:1903507,GO:1903827,GO:1903829,GO:1904029,GO:1904030,GO:1904666,GO:1904668,GO:1905818,GO:1905819,GO:1990023,GO:2000026,GO:2000058,GO:2000060,GO:2000112,GO:2000113,GO:2000177,GO:2000178,GO:2000647,GO:2000816,GO:2001141,GO:2001251	2.7.11.21	ko:K06631	ko04068,ko04110,ko04114,ko04914,map04068,map04110,map04114,map04914	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03036	-	-	-	POLO_box,Pkinase
k59_924932_2	187272.Mlg_0930	2.3e-68	214.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,1WXNU@135613|Chromatiales	135613|Chromatiales	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
k59_886930_1	314278.NB231_08650	6.36e-87	283.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1SYTD@1236|Gammaproteobacteria,1X2IM@135613|Chromatiales	135613|Chromatiales	EO	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M1,Peptidase_M28
k59_573212_1	754476.Q7A_505	3.74e-37	134.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,45ZR2@72273|Thiotrichales	72273|Thiotrichales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
k59_573212_2	765911.Thivi_4179	5.79e-16	75.1	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1WYEN@135613|Chromatiales	135613|Chromatiales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
k59_455632_1	335543.Sfum_3302	2.3e-124	373.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2MR5T@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
k59_377961_1	76114.ebA4061	3.43e-84	254.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJBY@28216|Betaproteobacteria,2KVSB@206389|Rhodocyclales	206389|Rhodocyclales	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_924973_1	1196324.A374_08274	8.65e-68	215.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	yngF	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_807209_1	1121422.AUMW01000025_gene326	4.07e-20	93.2	COG1960@1|root,COG1960@2|Bacteria,1VSGE@1239|Firmicutes,24Y78@186801|Clostridia,264P7@186807|Peptococcaceae	186801|Clostridia	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_537137_1	1122182.KB903813_gene2380	3.99e-21	92.8	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4DBD7@85008|Micromonosporales	201174|Actinobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
k59_1243456_1	29581.BW37_01577	1.21e-71	217.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,473FT@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
k59_1243456_2	396588.Tgr7_0988	8.96e-25	100.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria,1WWDD@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
k59_924989_1	857087.Metme_3027	9.56e-94	281.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1XDTQ@135618|Methylococcales	135618|Methylococcales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1010099_1	670307.HYPDE_32978	2.38e-15	74.3	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2UBQA@28211|Alphaproteobacteria,3N72C@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k59_1010099_2	717785.HYPMC_2769	2.7e-14	69.7	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2U9IZ@28211|Alphaproteobacteria,3N75M@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
k59_1161111_1	880072.Desac_0388	4.19e-51	178.0	COG2203@1|root,COG2206@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2WKJ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
k59_104441_1	985054.JQEZ01000006_gene99	7.63e-50	179.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2UDP0@28211|Alphaproteobacteria,4NBKE@97050|Ruegeria	28211|Alphaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
k59_422101_1	1123518.ARWI01000001_gene154	4.3e-33	121.0	COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,1RPT7@1236|Gammaproteobacteria,460JP@72273|Thiotrichales	72273|Thiotrichales	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
k59_651123_1	1123401.JHYQ01000021_gene1056	2.65e-94	283.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,1RNGA@1236|Gammaproteobacteria,460B1@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
k59_1200567_1	1504981.KO116_2486	7.2e-13	66.2	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1XJW7@135619|Oceanospirillales	135619|Oceanospirillales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_1200567_2	472759.Nhal_0175	6.48e-66	208.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1WX1Y@135613|Chromatiales	135613|Chromatiales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_497426_1	314278.NB231_08127	2.8e-109	349.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_1163411_1	641491.DND132_2843	1.49e-28	115.0	COG2911@1|root,COG2911@2|Bacteria,1R9JC@1224|Proteobacteria,42PED@68525|delta/epsilon subdivisions,2WMBZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Dicarboxylate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctA-YdbH
k59_1163411_2	879212.DespoDRAFT_02042	3.71e-18	77.8	2EIZA@1|root,33CQH@2|Bacteria,1NJDM@1224|Proteobacteria,42WT9@68525|delta/epsilon subdivisions,2WT1N@28221|Deltaproteobacteria,2MMAE@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_19
k59_1163411_3	247490.KSU1_D0305	1.81e-15	72.4	COG3784@1|root,COG3784@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1318)	ydbL	-	-	ko:K09978	-	-	-	-	ko00000	-	-	-	DUF1318
k59_144057_1	1122963.AUHB01000010_gene1589	1.32e-49	178.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,36XPJ@31993|Methylocystaceae	28211|Alphaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_575581_1	349521.HCH_02398	1.82e-29	122.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1XJG7@135619|Oceanospirillales	135619|Oceanospirillales	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
k59_540145_1	517418.Ctha_1151	1.09e-60	209.0	COG0068@1|root,COG0068@2|Bacteria,1FDST@1090|Chlorobi	1090|Chlorobi	O	Belongs to the carbamoyltransferase HypF family	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_693493_2	95619.PM1_0204980	1.24e-38	140.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	dna polymerase III delta subunit	holA	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
k59_809378_1	880072.Desac_0060	1.35e-78	248.0	COG1061@1|root,COG1061@2|Bacteria,1QWMJ@1224|Proteobacteria,42NXF@68525|delta/epsilon subdivisions,2WJWA@28221|Deltaproteobacteria,2MRP4@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
k59_732306_2	1232437.KL662039_gene2081	5.85e-36	124.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,42VDU@68525|delta/epsilon subdivisions,2WQZ5@28221|Deltaproteobacteria,2MKK3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_927190_1	760192.Halhy_4273	4.84e-19	88.2	COG3214@1|root,COG3214@2|Bacteria,4NGF2@976|Bacteroidetes,1ISPP@117747|Sphingobacteriia	976|Bacteroidetes	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
k59_183372_1	326297.Sama_0755	4.9e-101	314.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RYFT@1236|Gammaproteobacteria,2QACK@267890|Shewanellaceae	1236|Gammaproteobacteria	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_615524_1	1123503.KB908056_gene1856	3.46e-19	83.2	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2U95Q@28211|Alphaproteobacteria,2KGVF@204458|Caulobacterales	204458|Caulobacterales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
k59_615524_2	549.BW31_02030	0.000161	44.3	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,3VYH1@53335|Pantoea	1236|Gammaproteobacteria	D	overexpression in Bacillus subtilis inhibits septation in the dividing cell	yceF	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
k59_575618_1	316067.Geob_3124	9.38e-48	164.0	COG3547@1|root,COG3547@2|Bacteria,1QYJU@1224|Proteobacteria	1224|Proteobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_302162_1	1287276.X752_00825	5.58e-37	139.0	COG0404@1|root,COG0404@2|Bacteria,1R3WG@1224|Proteobacteria,2U0M4@28211|Alphaproteobacteria,43HEW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
k59_1012098_1	59463.ENSMLUP00000013894	2.3e-107	313.0	COG0450@1|root,KOG0854@2759|Eukaryota,38CN4@33154|Opisthokonta,3BBQ4@33208|Metazoa,3CW2U@33213|Bilateria,484YP@7711|Chordata,48ZKW@7742|Vertebrata,3J4RN@40674|Mammalia,4KPE1@9397|Chiroptera	33208|Metazoa	O	C-terminal domain of 1-Cys peroxiredoxin	PRDX6	GO:0000302,GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004601,GO:0004602,GO:0004620,GO:0004623,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009636,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0012505,GO:0016042,GO:0016043,GO:0016192,GO:0016209,GO:0016298,GO:0016491,GO:0016684,GO:0016787,GO:0016788,GO:0016999,GO:0017001,GO:0017144,GO:0019219,GO:0019222,GO:0019637,GO:0019899,GO:0022607,GO:0030030,GO:0030031,GO:0030141,GO:0031323,GO:0031325,GO:0031410,GO:0031625,GO:0031974,GO:0031982,GO:0031983,GO:0032060,GO:0032940,GO:0033120,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042221,GO:0042582,GO:0042737,GO:0042743,GO:0042744,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043484,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044389,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045935,GO:0046434,GO:0046475,GO:0046486,GO:0046503,GO:0046903,GO:0046983,GO:0047499,GO:0048024,GO:0048026,GO:0048471,GO:0048518,GO:0048522,GO:0050684,GO:0050685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051179,GO:0051186,GO:0051187,GO:0051234,GO:0051252,GO:0051254,GO:0051716,GO:0052689,GO:0055114,GO:0060205,GO:0060255,GO:0065007,GO:0070013,GO:0070887,GO:0071704,GO:0071840,GO:0072593,GO:0080090,GO:0097237,GO:0097708,GO:0098754,GO:0098869,GO:0099503,GO:0120031,GO:0120036,GO:1901575,GO:1901700,GO:1903311,GO:1903313,GO:1990748	1.11.1.15,1.11.1.7	ko:K11188	ko00940,ko01100,ko01110,map00940,map01100,map01110	-	R00602,R02596,R03919,R04007,R07443	RC00034	ko00000,ko00001,ko01000	-	-	-	1-cysPrx_C,AhpC-TSA
k59_1163461_1	61853.ENSNLEP00000004467	9.29e-128	376.0	COG0114@1|root,KOG1317@2759|Eukaryota,38GHX@33154|Opisthokonta,3BB3C@33208|Metazoa,3CUSS@33213|Bilateria,487GR@7711|Chordata,490UB@7742|Vertebrata,3J6FA@40674|Mammalia,35AVC@314146|Euarchontoglires,4M76F@9443|Primates	33208|Metazoa	C	Fumarate hydratase	FH	GO:0001894,GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0031974,GO:0032501,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0048871,GO:0048872,GO:0048873,GO:0055114,GO:0060249,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_1047605_1	153948.NAL212_3119	9.05e-95	286.0	COG3677@1|root,COG3677@2|Bacteria,1R3ZS@1224|Proteobacteria,2WFCR@28216|Betaproteobacteria	1224|Proteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_1245931_1	384765.SIAM614_18869	1.26e-56	191.0	COG1940@1|root,COG1940@2|Bacteria,1MVGQ@1224|Proteobacteria,2TRFX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,ROK
k59_183387_1	1094184.KWO_0113475	3.03e-05	45.4	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,1X32Q@135614|Xanthomonadales	135614|Xanthomonadales	S	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
k59_183387_2	265072.Mfla_1237	1.86e-35	125.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,2VU39@28216|Betaproteobacteria,2KMX2@206350|Nitrosomonadales	206350|Nitrosomonadales	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
k59_575637_1	96561.Dole_3264	7.46e-31	127.0	COG0784@1|root,COG4191@1|root,COG5000@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MI5F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SBP_bac_3
k59_1063985_2	999141.GME_04387	1.16e-142	421.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1XIU0@135619|Oceanospirillales	135619|Oceanospirillales	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_476253_1	580332.Slit_0924	1.05e-49	176.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2VJK5@28216|Betaproteobacteria	28216|Betaproteobacteria	G	pyruvate phosphate dikinase	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_476253_2	388413.ALPR1_15439	1.01e-12	68.6	COG0725@1|root,COG2273@1|root,COG0725@2|Bacteria,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,47NAB@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
k59_319368_1	880072.Desac_0553	1.25e-104	315.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2MQ97@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
k59_515699_1	1001585.MDS_0637	9.73e-09	62.8	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1YCQW@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Mechanosensitive ion channel inner membrane domain 1	kefA	GO:0005575,GO:0005623,GO:0005886,GO:0006884,GO:0008150,GO:0008361,GO:0009987,GO:0009992,GO:0016020,GO:0016043,GO:0019725,GO:0030104,GO:0032535,GO:0042592,GO:0044464,GO:0048878,GO:0055082,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K05802,ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.1.2,1.A.23.1.3	-	-	MS_channel,MscS_TM,MscS_porin
k59_6346_1	1232437.KL662016_gene1045	1.74e-117	350.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42QI1@68525|delta/epsilon subdivisions,2WMJR@28221|Deltaproteobacteria,2MMRG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_946397_1	765912.Thimo_1933	3.83e-82	263.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,1RMJS@1236|Gammaproteobacteria,1WW9Q@135613|Chromatiales	135613|Chromatiales	C	belongs to the CobB CobQ family	-	-	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
k59_750476_1	1038859.AXAU01000002_gene255	7.6e-115	347.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2TYCG@28211|Alphaproteobacteria,3JTS9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_554622_1	690850.Desaf_0419	4.49e-32	120.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42Q3D@68525|delta/epsilon subdivisions,2WM24@28221|Deltaproteobacteria,2MGKS@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11
k59_398308_1	1304885.AUEY01000040_gene1606	9.53e-74	235.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria,2MJDX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_280371_1	1167006.UWK_00417	4.2e-87	264.0	COG0705@1|root,COG0705@2|Bacteria,1PRTP@1224|Proteobacteria,42M6N@68525|delta/epsilon subdivisions,2WJW4@28221|Deltaproteobacteria,2MJR6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
k59_593908_1	748247.AZKH_2197	7.86e-30	121.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1MZV7@1224|Proteobacteria,2WI0C@28216|Betaproteobacteria,2KZVF@206389|Rhodocyclales	206389|Rhodocyclales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,PAS
k59_633339_1	545264.KB898747_gene581	2.93e-107	324.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1WVXY@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
k59_633345_1	290512.Paes_0605	2.09e-43	159.0	COG3930@1|root,COG3930@2|Bacteria,1FECR@1090|Chlorobi	1090|Chlorobi	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
k59_986091_2	945543.VIBR0546_07652	1.76e-47	160.0	COG1595@1|root,COG1595@2|Bacteria,1R9ZN@1224|Proteobacteria,1S27W@1236|Gammaproteobacteria,1Y2D5@135623|Vibrionales	135623|Vibrionales	K	Belongs to the sigma-70 factor family. ECF subfamily	sigV	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_986091_3	696748.ASU2_07285	1.37e-28	112.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1Y7AR@135625|Pasteurellales	135625|Pasteurellales	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_867926_2	1123054.KB907713_gene537	5.26e-59	200.0	COG0366@1|root,COG0366@2|Bacteria,1Q8Y2@1224|Proteobacteria,1RQV0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG0366 Glycosidases	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Malt_amylase_C
k59_319450_1	717785.HYPMC_3257	5.63e-226	632.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,3N8ZI@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
k59_828869_1	9913.ENSBTAP00000054889	3.1e-208	587.0	KOG1190@1|root,KOG1190@2759|Eukaryota,38H7H@33154|Opisthokonta,3B9RH@33208|Metazoa,3CRKU@33213|Bilateria,483UE@7711|Chordata,48VI4@7742|Vertebrata,3J3SY@40674|Mammalia,4IYJU@91561|Cetartiodactyla	33208|Metazoa	A	Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT Tau exon 10 (By similarity)	PTBP1	GO:0000003,GO:0000014,GO:0000226,GO:0000375,GO:0000377,GO:0000381,GO:0000398,GO:0000900,GO:0000956,GO:0001067,GO:0001069,GO:0002009,GO:0002165,GO:0002791,GO:0002793,GO:0003006,GO:0003205,GO:0003231,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006259,GO:0006355,GO:0006357,GO:0006396,GO:0006397,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007163,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007291,GO:0007292,GO:0007308,GO:0007309,GO:0007319,GO:0007349,GO:0007389,GO:0007399,GO:0007444,GO:0007472,GO:0007476,GO:0007507,GO:0007552,GO:0007560,GO:0008103,GO:0008150,GO:0008152,GO:0008380,GO:0008586,GO:0008587,GO:0009056,GO:0009057,GO:0009653,GO:0009791,GO:0009798,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0009994,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010638,GO:0010646,GO:0010647,GO:0010720,GO:0010817,GO:0010975,GO:0010976,GO:0016032,GO:0016043,GO:0016070,GO:0016071,GO:0016325,GO:0016787,GO:0016788,GO:0017148,GO:0019080,GO:0019081,GO:0019219,GO:0019220,GO:0019222,GO:0019439,GO:0019953,GO:0021700,GO:0022008,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030154,GO:0030371,GO:0030951,GO:0030952,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0032024,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032880,GO:0032991,GO:0033043,GO:0033119,GO:0034248,GO:0034249,GO:0034250,GO:0034641,GO:0034655,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0036002,GO:0042995,GO:0043005,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043484,GO:0043487,GO:0043488,GO:0043489,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044306,GO:0044403,GO:0044419,GO:0044424,GO:0044463,GO:0044464,GO:0044703,GO:0045182,GO:0045595,GO:0045596,GO:0045597,GO:0045664,GO:0045666,GO:0045727,GO:0045893,GO:0045934,GO:0045935,GO:0045937,GO:0045944,GO:0046011,GO:0046483,GO:0046700,GO:0046883,GO:0046887,GO:0048024,GO:0048025,GO:0048232,GO:0048255,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048563,GO:0048569,GO:0048583,GO:0048584,GO:0048599,GO:0048609,GO:0048646,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0050684,GO:0050686,GO:0050708,GO:0050714,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050796,GO:0050848,GO:0050850,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051147,GO:0051148,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0060429,GO:0060562,GO:0061013,GO:0065007,GO:0065008,GO:0070201,GO:0070884,GO:0070886,GO:0070935,GO:0071704,GO:0071840,GO:0072359,GO:0075522,GO:0080090,GO:0090079,GO:0090087,GO:0090276,GO:0090277,GO:0090304,GO:0090305,GO:0097159,GO:0097458,GO:0106056,GO:0106058,GO:0120025,GO:0120035,GO:0120038,GO:0140097,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1902531,GO:1902533,GO:1902680,GO:1903311,GO:1903312,GO:1903506,GO:1903508,GO:1903530,GO:1903532,GO:1904409,GO:1904411,GO:1904951,GO:1990904,GO:2000026,GO:2000112,GO:2000113,GO:2001141	-	ko:K08524,ko:K13218,ko:K14948,ko:K17844	ko03320,ko04151,ko04659,ko04919,ko04920,ko04932,ko04976,ko05160,ko05200,ko05202,ko05216,ko05222,ko05223,ko05226,map03320,map04151,map04659,map04919,map04920,map04932,map04976,map05160,map05200,map05202,map05216,map05222,map05223,map05226	-	-	-	ko00000,ko00001,ko03000,ko03019,ko03041,ko03310	-	-	-	RRM_1,RRM_5
k59_633389_1	443144.GM21_2868	2.37e-66	210.0	COG1924@1|root,COG1924@2|Bacteria,1RDZA@1224|Proteobacteria,42RYS@68525|delta/epsilon subdivisions,2WNJX@28221|Deltaproteobacteria,43T2B@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k59_672324_1	338966.Ppro_2672	2.66e-07	50.8	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,43US0@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_672324_2	1089553.Tph_c18120	9.66e-12	64.7	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,42EPZ@68295|Thermoanaerobacterales	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
k59_946514_1	1268635.Loa_02782	1.45e-123	361.0	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,1RPZY@1236|Gammaproteobacteria,1JDUY@118969|Legionellales	118969|Legionellales	F	IMP dehydrogenase / GMP reductase domain	guaC	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
k59_1103414_2	1037409.BJ6T_03170	1.14e-09	61.6	COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,1QW6N@1224|Proteobacteria,2TWQ3@28211|Alphaproteobacteria,3JU8D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,GAF_2,Guanylate_cyc,HAMP,dCache_1
k59_85226_1	314278.NB231_05801	3.24e-30	110.0	2CECF@1|root,32RZM@2|Bacteria,1N130@1224|Proteobacteria,1S98I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	pilin assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_85226_2	123899.JPQP01000023_gene2818	2.09e-50	165.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2VPZU@28216|Betaproteobacteria,3T3GD@506|Alcaligenaceae	28216|Betaproteobacteria	S	nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
k59_515802_1	391612.CY0110_25486	8.44e-37	144.0	COG0642@1|root,COG2202@1|root,COG3899@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,COG5002@2|Bacteria,1GD97@1117|Cyanobacteria,3KHHW@43988|Cyanothece	1117|Cyanobacteria	T	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_9,Response_reg
k59_1025173_1	1169143.KB911055_gene2513	2.77e-120	353.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2VJ5H@28216|Betaproteobacteria,1K2CZ@119060|Burkholderiaceae	28216|Betaproteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_789887_1	1179778.PMM47T1_17015	6.49e-30	123.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1182016_2	96561.Dole_0431	2.02e-62	204.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42MPR@68525|delta/epsilon subdivisions,2WNM3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Multicopper	cumA	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
k59_319497_1	1265505.ATUG01000001_gene4623	1.97e-47	164.0	COG0477@1|root,COG2814@2|Bacteria,1R518@1224|Proteobacteria,43B4F@68525|delta/epsilon subdivisions,2WIQ4@28221|Deltaproteobacteria,2MIEM@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1064202_1	1234364.AMSF01000085_gene2930	6.72e-37	142.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1X3R5@135614|Xanthomonadales	135614|Xanthomonadales	JKL	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C,RhlB
k59_1025216_1	511145.b4053	2.1e-35	131.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,3XMIC@561|Escherichia	1236|Gammaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine	alr	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019842,GO:0030170,GO:0030203,GO:0034645,GO:0036094,GO:0036361,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	iEC55989_1330.EC55989_1285,iECIAI39_1322.ECIAI39_1880,iECO103_1326.ECO103_1292,iECO26_1355.ECO26_1703,iECSE_1348.ECSE_1238,iECUMN_1333.ECUMN_1479,iECW_1372.ECW_m1275,iEKO11_1354.EKO11_2666,iEcE24377_1341.EcE24377A_1335,iPC815.YPO0321,iSBO_1134.SBO_4064,iSbBS512_1146.SbBS512_E4542,iWFL_1372.ECW_m1275,iYL1228.KPN_04440	Ala_racemase_C,Ala_racemase_N
k59_1025216_2	391615.ABSJ01000026_gene114	2.41e-61	198.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,1S50X@1236|Gammaproteobacteria,1J761@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
k59_437112_1	697281.Mahau_0242	2.14e-66	214.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,42FEW@68295|Thermoanaerobacterales	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_515841_1	1207063.P24_08759	1.12e-24	106.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,2JPTB@204441|Rhodospirillales	204441|Rhodospirillales	MU	Secretion system type I outer membrane efflux pump lipoprotein NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
k59_437135_1	1349767.GJA_1708	8.57e-36	139.0	COG1231@1|root,COG1231@2|Bacteria,1MWPH@1224|Proteobacteria,2VIS4@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
k59_1106375_1	96561.Dole_0426	5.28e-98	301.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,2MHU3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,sCache_3_2
k59_792661_1	159450.NH14_11955	1.12e-48	173.0	COG2985@1|root,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,2VIHY@28216|Betaproteobacteria,1K26P@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
k59_244446_1	1121918.ARWE01000001_gene2296	1.05e-30	122.0	COG0389@1|root,COG0389@2|Bacteria,1RBTJ@1224|Proteobacteria,42QY9@68525|delta/epsilon subdivisions,2WMTI@28221|Deltaproteobacteria,43S6H@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	impB/mucB/samB family	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
k59_831859_1	335543.Sfum_2417	3.74e-22	95.1	COG3009@1|root,COG3009@2|Bacteria,1N8BW@1224|Proteobacteria,42UW2@68525|delta/epsilon subdivisions,2WQFD@28221|Deltaproteobacteria,2MS52@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
k59_322519_1	1121405.dsmv_0154	4.82e-107	321.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N9U@68525|delta/epsilon subdivisions,2WINY@28221|Deltaproteobacteria,2MHR0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	tmcB	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
k59_244460_1	1121405.dsmv_1599	2.63e-76	248.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,2MIKW@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_792674_1	748247.AZKH_1715	8.61e-21	93.2	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,2VS6R@28216|Betaproteobacteria,2KWFR@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_714651_1	13616.ENSMODP00000002157	1.3e-102	300.0	KOG2240@1|root,KOG2240@2759|Eukaryota,39KNZ@33154|Opisthokonta,3BH53@33208|Metazoa,3CV24@33213|Bilateria,488DT@7711|Chordata,495ZJ@7742|Vertebrata,3J1RJ@40674|Mammalia,4K87J@9263|Metatheria	33208|Metazoa	K	Belongs to the NAC-beta family	BTF3	GO:0001701,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006366,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009790,GO:0009792,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032501,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048856,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K01527	ko04214,map04214	-	-	-	ko00000,ko00001	-	-	-	NAC
k59_597119_1	1298867.AUES01000051_gene4506	1.11e-28	119.0	COG1994@1|root,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,2U0H8@28211|Alphaproteobacteria,3K33G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Peptidase, M50 family	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Biotin_lipoyl_2,HlyD_3,PqqD
k59_949489_1	1121033.AUCF01000018_gene5842	5.92e-84	265.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,2JP99@204441|Rhodospirillales	204441|Rhodospirillales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_244479_1	566466.NOR53_3686	5.15e-169	482.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,1JA8Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	COG1541 Coenzyme F390 synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C_2
k59_126900_1	96561.Dole_0148	3.62e-37	144.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2MJNR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_48604_1	765914.ThisiDRAFT_1474	4.21e-65	221.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1WVXH@135613|Chromatiales	135613|Chromatiales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
k59_322567_1	1415780.JPOG01000001_gene2148	2.14e-77	235.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1X5KF@135614|Xanthomonadales	135614|Xanthomonadales	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_322571_1	1121405.dsmv_3138	2.22e-77	256.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MIBK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_283405_1	555779.Dthio_PD0351	2.19e-53	186.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MAFI@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	pfam abc1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
k59_1067052_1	1122605.KB893627_gene2960	6.69e-10	57.4	COG0662@1|root,COG0662@2|Bacteria,4NV84@976|Bacteroidetes,1IYKN@117747|Sphingobacteriia	976|Bacteroidetes	G	SPTR Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_1067052_2	984262.SGRA_2394	4.94e-19	82.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1ISJH@117747|Sphingobacteriia	976|Bacteroidetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
k59_126927_1	1120949.KB903313_gene494	3.98e-54	175.0	COG0251@1|root,COG0251@2|Bacteria,2GQ40@201174|Actinobacteria	201174|Actinobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
k59_675360_1	1026970.XP_008850394.1	6.97e-114	351.0	COG5069@1|root,KOG0035@2759|Eukaryota,38C3U@33154|Opisthokonta,3BB7X@33208|Metazoa,3CV9K@33213|Bilateria,48697@7711|Chordata,48VA4@7742|Vertebrata,3J2Q9@40674|Mammalia,35B7V@314146|Euarchontoglires,4PW7I@9989|Rodentia	33208|Metazoa	Z	Alpha-actinin-1	ACTN1	GO:0000902,GO:0000904,GO:0001505,GO:0001725,GO:0001726,GO:0002376,GO:0002520,GO:0002576,GO:0003674,GO:0003676,GO:0003712,GO:0003713,GO:0003723,GO:0003725,GO:0003779,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005523,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005856,GO:0005886,GO:0005903,GO:0005911,GO:0005912,GO:0005913,GO:0005915,GO:0005916,GO:0005923,GO:0005924,GO:0005925,GO:0005938,GO:0006810,GO:0006887,GO:0006996,GO:0007010,GO:0007015,GO:0007044,GO:0007045,GO:0007155,GO:0007160,GO:0007275,GO:0007517,GO:0007519,GO:0008092,GO:0008150,GO:0009653,GO:0009888,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010556,GO:0010557,GO:0010604,GO:0010646,GO:0010927,GO:0010941,GO:0012505,GO:0012506,GO:0014704,GO:0014706,GO:0014902,GO:0014904,GO:0015629,GO:0016020,GO:0016043,GO:0016192,GO:0016328,GO:0017166,GO:0019219,GO:0019222,GO:0019904,GO:0022607,GO:0022610,GO:0023051,GO:0030016,GO:0030017,GO:0030018,GO:0030027,GO:0030029,GO:0030036,GO:0030054,GO:0030055,GO:0030057,GO:0030097,GO:0030099,GO:0030141,GO:0030154,GO:0030220,GO:0030239,GO:0030274,GO:0030374,GO:0030425,GO:0030485,GO:0030486,GO:0030659,GO:0030667,GO:0030863,GO:0030864,GO:0030865,GO:0031032,GO:0031045,GO:0031090,GO:0031091,GO:0031093,GO:0031143,GO:0031252,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031410,GO:0031589,GO:0031674,GO:0031974,GO:0031982,GO:0031983,GO:0032127,GO:0032432,GO:0032501,GO:0032502,GO:0032879,GO:0032940,GO:0032989,GO:0034329,GO:0034330,GO:0034332,GO:0034333,GO:0034774,GO:0036344,GO:0036477,GO:0042383,GO:0042641,GO:0042692,GO:0042802,GO:0042803,GO:0042805,GO:0042981,GO:0042995,GO:0043005,GO:0043067,GO:0043197,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043296,GO:0043462,GO:0043495,GO:0044085,GO:0044291,GO:0044309,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044433,GO:0044444,GO:0044446,GO:0044448,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045055,GO:0045202,GO:0045214,GO:0045216,GO:0045935,GO:0046903,GO:0046928,GO:0046983,GO:0048041,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048646,GO:0048731,GO:0048741,GO:0048747,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050804,GO:0050839,GO:0051015,GO:0051017,GO:0051046,GO:0051049,GO:0051146,GO:0051171,GO:0051173,GO:0051179,GO:0051219,GO:0051234,GO:0051252,GO:0051254,GO:0051270,GO:0051271,GO:0051336,GO:0051393,GO:0051588,GO:0051639,GO:0055001,GO:0055002,GO:0060205,GO:0060255,GO:0060341,GO:0060537,GO:0060538,GO:0061061,GO:0061572,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070160,GO:0070161,GO:0070925,GO:0071840,GO:0071944,GO:0080090,GO:0090636,GO:0090637,GO:0097159,GO:0097433,GO:0097435,GO:0097447,GO:0097458,GO:0097517,GO:0097708,GO:0098588,GO:0098794,GO:0098805,GO:0098862,GO:0099080,GO:0099081,GO:0099177,GO:0099503,GO:0099512,GO:0099568,GO:0120025,GO:0120038,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:1990357,GO:2001141	-	ko:K05699	ko04510,ko04520,ko04530,ko04670,ko04810,ko05146,ko05203,ko05322,map04510,map04520,map04530,map04670,map04810,map05146,map05203,map05322	-	-	-	ko00000,ko00001,ko04131,ko04147,ko04812	-	-	-	CH,EF-hand_6,EF-hand_8,EFhand_Ca_insen,Spectrin
k59_597203_1	314345.SPV1_05208	8.32e-12	70.5	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_8,PAS_9,Response_reg
k59_557779_1	96561.Dole_1876	4.28e-79	258.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2MHN2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
k59_557789_1	1232410.KI421426_gene1466	1.15e-71	236.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,43UJP@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8,PAS_3,PAS_4,Sigma54_activat
k59_9365_1	323848.Nmul_A0210	1.05e-54	185.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,37240@32003|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
k59_9365_2	765910.MARPU_00860	2.51e-60	190.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,1S263@1236|Gammaproteobacteria,1WX7S@135613|Chromatiales	135613|Chromatiales	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
k59_88433_1	9606.ENSP00000336790	1.76e-88	268.0	KOG4571@1|root,KOG4571@2759|Eukaryota,38BSX@33154|Opisthokonta,3BJ5H@33208|Metazoa,3D1EH@33213|Bilateria,489PP@7711|Chordata,490RQ@7742|Vertebrata,3JAA7@40674|Mammalia,35GF3@314146|Euarchontoglires,4MDVQ@9443|Primates,4MV30@9604|Hominidae	33208|Metazoa	K	Activating transcription factor 4	ATF4	GO:0000976,GO:0000977,GO:0000978,GO:0000980,GO:0000981,GO:0000982,GO:0000987,GO:0000988,GO:0000989,GO:0001012,GO:0001067,GO:0001076,GO:0001077,GO:0001085,GO:0001102,GO:0001158,GO:0001228,GO:0001817,GO:0001819,GO:0001932,GO:0001934,GO:0002165,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003712,GO:0003713,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005667,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005996,GO:0006006,GO:0006082,GO:0006094,GO:0006139,GO:0006351,GO:0006355,GO:0006356,GO:0006357,GO:0006366,GO:0006417,GO:0006446,GO:0006464,GO:0006486,GO:0006487,GO:0006520,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006725,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006915,GO:0006950,GO:0006979,GO:0006984,GO:0006986,GO:0007154,GO:0007165,GO:0007186,GO:0007214,GO:0007275,GO:0007399,GO:0007552,GO:0007591,GO:0007623,GO:0008022,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009267,GO:0009299,GO:0009311,GO:0009314,GO:0009411,GO:0009416,GO:0009605,GO:0009628,GO:0009636,GO:0009719,GO:0009791,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010042,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010574,GO:0010575,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010660,GO:0010661,GO:0010941,GO:0010942,GO:0010959,GO:0010966,GO:0012501,GO:0012505,GO:0014070,GO:0016020,GO:0016021,GO:0016051,GO:0016070,GO:0016071,GO:0016234,GO:0017148,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019438,GO:0019538,GO:0019725,GO:0019752,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022008,GO:0023051,GO:0023052,GO:0023056,GO:0030003,GO:0030154,GO:0030176,GO:0030182,GO:0030275,GO:0030425,GO:0030968,GO:0031224,GO:0031227,GO:0031252,GO:0031253,GO:0031256,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031399,GO:0031401,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0031984,GO:0032055,GO:0032057,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032589,GO:0032590,GO:0032774,GO:0032872,GO:0032874,GO:0032879,GO:0032922,GO:0032991,GO:0033554,GO:0033613,GO:0034198,GO:0034248,GO:0034249,GO:0034391,GO:0034393,GO:0034399,GO:0034599,GO:0034620,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034976,GO:0035073,GO:0035074,GO:0035209,GO:0035210,GO:0035326,GO:0035556,GO:0035690,GO:0035966,GO:0035967,GO:0036003,GO:0036091,GO:0036211,GO:0036293,GO:0036294,GO:0036477,GO:0036499,GO:0042149,GO:0042175,GO:0042221,GO:0042303,GO:0042325,GO:0042327,GO:0042493,GO:0042592,GO:0042594,GO:0042789,GO:0042981,GO:0042995,GO:0043005,GO:0043065,GO:0043067,GO:0043068,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043266,GO:0043267,GO:0043269,GO:0043270,GO:0043271,GO:0043408,GO:0043410,GO:0043412,GO:0043413,GO:0043436,GO:0043522,GO:0043523,GO:0043525,GO:0043555,GO:0043558,GO:0043565,GO:0043618,GO:0043619,GO:0043620,GO:0044070,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044798,GO:0045893,GO:0045935,GO:0045937,GO:0045943,GO:0045944,GO:0045947,GO:0046328,GO:0046330,GO:0046364,GO:0046483,GO:0046486,GO:0046685,GO:0046982,GO:0046983,GO:0048511,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051050,GO:0051051,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0060255,GO:0060359,GO:0060548,GO:0061394,GO:0061395,GO:0065007,GO:0065008,GO:0070013,GO:0070059,GO:0070085,GO:0070167,GO:0070169,GO:0070302,GO:0070304,GO:0070482,GO:0070887,GO:0071214,GO:0071241,GO:0071242,GO:0071243,GO:0071248,GO:0071287,GO:0071310,GO:0071407,GO:0071417,GO:0071453,GO:0071478,GO:0071482,GO:0071495,GO:0071496,GO:0071704,GO:0071867,GO:0071868,GO:0071869,GO:0071870,GO:0071944,GO:0072503,GO:0072507,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090575,GO:0090649,GO:0090650,GO:0097159,GO:0097190,GO:0097193,GO:0097413,GO:0097447,GO:0097458,GO:0097659,GO:0098590,GO:0098771,GO:0098827,GO:0104004,GO:0120025,GO:0120038,GO:0140110,GO:1900407,GO:1900408,GO:1901135,GO:1901137,GO:1901214,GO:1901215,GO:1901216,GO:1901360,GO:1901362,GO:1901363,GO:1901522,GO:1901564,GO:1901566,GO:1901576,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902235,GO:1902237,GO:1902531,GO:1902533,GO:1902680,GO:1902882,GO:1902883,GO:1903201,GO:1903202,GO:1903203,GO:1903204,GO:1903350,GO:1903351,GO:1903506,GO:1903508,GO:1903793,GO:1905459,GO:1905461,GO:1905897,GO:1905898,GO:1990037,GO:1990440,GO:1990589,GO:1990590,GO:1990617,GO:1990737,GO:1990837,GO:1990928,GO:2000026,GO:2000112,GO:2000113,GO:2000118,GO:2000120,GO:2001141,GO:2001233,GO:2001235,GO:2001242,GO:2001244	-	ko:K04374	ko04010,ko04022,ko04137,ko04141,ko04151,ko04210,ko04211,ko04212,ko04214,ko04261,ko04668,ko04720,ko04722,ko04725,ko04728,ko04911,ko04912,ko04915,ko04918,ko04922,ko04925,ko04926,ko04927,ko04932,ko04934,ko05030,ko05031,ko05034,ko05161,ko05166,ko05203,ko05215,map04010,map04022,map04137,map04141,map04151,map04210,map04211,map04212,map04214,map04261,map04668,map04720,map04722,map04725,map04728,map04911,map04912,map04915,map04918,map04922,map04925,map04926,map04927,map04932,map04934,map05030,map05031,map05034,map05161,map05166,map05203,map05215	-	-	-	ko00000,ko00001,ko03000	-	-	-	bZIP_1
k59_440375_1	83406.HDN1F_27800	5.33e-35	130.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,1RPNI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_440390_1	1121405.dsmv_1736	3.89e-79	245.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2MMXX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_1224523_1	234267.Acid_2464	2.63e-46	169.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
k59_322679_1	27679.XP_010347573.1	8.2e-262	721.0	KOG2758@1|root,KOG2758@2759|Eukaryota,38C5H@33154|Opisthokonta,3BAPV@33208|Metazoa,3CZ3T@33213|Bilateria,48252@7711|Chordata,4903Q@7742|Vertebrata,3J5SI@40674|Mammalia,35D4B@314146|Euarchontoglires,4M89E@9443|Primates	33208|Metazoa	J	positive regulation of mRNA binding	EIF3E	GO:0000184,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005852,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016070,GO:0016071,GO:0016604,GO:0016605,GO:0017148,GO:0019222,GO:0019439,GO:0019538,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034641,GO:0034645,GO:0034655,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043603,GO:0043604,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045727,GO:0045947,GO:0046483,GO:0046700,GO:0047485,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902415,GO:1902416,GO:1905214,GO:1905216,GO:2000112,GO:2000113	-	ko:K03250	ko03013,ko05160,map03013,map05160	-	-	-	ko00000,ko00001,ko03012,ko03051,ko04147	-	-	-	PCI,eIF3_N
k59_989621_1	880072.Desac_1024	3.3e-63	207.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WKTU@28221|Deltaproteobacteria,2MQRV@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_832062_2	307480.IW16_14580	2.48e-22	94.7	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1HXC4@117743|Flavobacteriia,3ZPG7@59732|Chryseobacterium	976|Bacteroidetes	E	Asparaginase	-	-	3.4.19.5,3.5.1.1	ko:K01424,ko:K13051	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
k59_1224564_1	580332.Slit_0118	1.18e-18	91.3	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,44UY9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_792850_2	406124.ACPC01000017_gene645	5.99e-23	93.2	COG0454@1|root,COG0454@2|Bacteria,1V4EA@1239|Firmicutes,4HHBF@91061|Bacilli,1ZGG7@1386|Bacillus	91061|Bacilli	K	acetyltransferase	ysnE	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
k59_88519_1	1121403.AUCV01000005_gene216	2.98e-112	343.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria,2MHWI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_461003_1	1121405.dsmv_0777	1.06e-96	300.0	COG0309@1|root,COG0546@1|root,COG0309@2|Bacteria,COG0546@2|Bacteria,1N04A@1224|Proteobacteria,437IA@68525|delta/epsilon subdivisions,2WYKF@28221|Deltaproteobacteria,2MP0D@213118|Desulfobacterales	28221|Deltaproteobacteria	O	AIR synthase related protein, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
k59_543168_1	1307759.JOMJ01000003_gene1714	2.23e-79	263.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_228550_1	1307759.JOMJ01000003_gene1755	2.21e-70	232.0	COG4191@1|root,COG4191@2|Bacteria,1R7KQ@1224|Proteobacteria,42PAP@68525|delta/epsilon subdivisions,2WITB@28221|Deltaproteobacteria,2M8JR@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
k59_618430_2	986075.CathTA2_0037	2.89e-31	118.0	2AHMV@1|root,317ZT@2|Bacteria,1VPFH@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_774511_1	1267005.KB911260_gene3448	3.35e-44	151.0	COG5317@1|root,COG5317@2|Bacteria,1RJIA@1224|Proteobacteria,2U9ID@28211|Alphaproteobacteria,3N766@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1465)	MA20_18080	-	-	ko:K13592	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF1465
k59_1248394_1	572479.Hprae_0206	6.35e-16	80.5	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WBJB@53433|Halanaerobiales	186801|Clostridia	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_461028_1	932677.PAJ_0221	1.76e-15	80.5	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,1RR4Y@1236|Gammaproteobacteria,3W1FW@53335|Pantoea	1236|Gammaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	ocd2	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	iJN746.PP_4431	OCD_Mu_crystall
k59_228561_1	452637.Oter_3293	4.05e-98	304.0	COG0281@1|root,COG0281@2|Bacteria,46UI4@74201|Verrucomicrobia,3K7KY@414999|Opitutae	414999|Opitutae	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
k59_1050017_1	1395571.TMS3_0112790	3e-98	296.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	per	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_428601_1	1124780.ANNU01000062_gene557	3.91e-79	241.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,47KMI@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_344081_1	1158318.ATXC01000001_gene1083	1.44e-64	214.0	COG3303@1|root,COG3303@2|Bacteria,2G4ZH@200783|Aquificae	200783|Aquificae	P	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
k59_304875_1	472759.Nhal_1528	5.15e-16	76.6	2EBH3@1|root,335HM@2|Bacteria,1NDXE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_696308_1	332101.JIBU02000045_gene3293	3.94e-09	63.2	COG4191@1|root,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes	1239|Firmicutes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HATPase_c,HisKA,PAS,PAS_9,dCache_1
k59_110969_1	1120983.KB894570_gene1607	8.69e-40	144.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2TRA4@28211|Alphaproteobacteria,1JNK0@119043|Rhodobiaceae	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	MA20_42180	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_854092_1	1265503.KB905160_gene2501	1.18e-60	211.0	COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_813765_1	1265505.ATUG01000001_gene3102	3.43e-111	334.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2MHPU@213118|Desulfobacterales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
k59_1051586_1	1122919.KB905633_gene462	3.02e-18	98.2	COG0747@1|root,COG2133@1|root,COG3210@1|root,COG4733@1|root,COG4932@1|root,COG0747@2|Bacteria,COG2133@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,CHB_HEX_C_1,Cadherin-like,Cohesin,Flg_new,SLH,fn3
k59_1249998_1	688269.Theth_0842	0.000282	44.7	COG0639@1|root,COG0639@2|Bacteria,2GCVZ@200918|Thermotogae	200918|Thermotogae	T	PFAM metallophosphoesterase	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
k59_1249998_2	215803.DB30_7174	2.84e-75	229.0	COG0662@1|root,COG0662@2|Bacteria,1R4UW@1224|Proteobacteria,43C28@68525|delta/epsilon subdivisions,2X7CT@28221|Deltaproteobacteria,2Z3FI@29|Myxococcales	28221|Deltaproteobacteria	G	3-hydroxyanthranilic acid dioxygenase	-	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
k59_1249998_3	1123276.KB893268_gene5018	1.94e-18	85.5	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,47KPP@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
k59_187489_1	880072.Desac_0912	1.31e-14	78.6	COG5421@1|root,COG5421@2|Bacteria,1Q09S@1224|Proteobacteria,42WX8@68525|delta/epsilon subdivisions,2WTG9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1051594_1	247633.GP2143_07394	1.2e-34	130.0	29IES@1|root,305BZ@2|Bacteria,1RF1J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_854114_1	566466.NOR53_2723	2.41e-18	85.1	2DR4R@1|root,33A5Q@2|Bacteria,1NJDG@1224|Proteobacteria,1SH8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_973068_1	1121405.dsmv_2068	7.36e-74	244.0	COG0433@1|root,COG0433@2|Bacteria,1R7B1@1224|Proteobacteria,42NW4@68525|delta/epsilon subdivisions,2X6WX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1250021_1	1304885.AUEY01000002_gene374	5.1e-60	192.0	COG0735@1|root,COG1918@1|root,COG0735@2|Bacteria,COG1918@2|Bacteria,1RDWJ@1224|Proteobacteria,42P61@68525|delta/epsilon subdivisions,2X5PQ@28221|Deltaproteobacteria,2MJ7H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR,FeoA
k59_620122_1	1089553.Tph_c17700	3.99e-49	178.0	COG0425@1|root,COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0425@2|Bacteria,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,42EW6@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
k59_148678_1	1205683.CAKR01000030_gene4135	2.82e-81	253.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,41D9Z@629|Yersinia	1236|Gammaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
k59_112661_1	290397.Adeh_1659	3.96e-100	307.0	COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
k59_813819_1	1348114.OM33_17415	4.18e-23	104.0	COG3713@1|root,COG3713@2|Bacteria,1MWQN@1224|Proteobacteria,1TBEV@1236|Gammaproteobacteria,2Q3FW@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	MltA-interacting protein MipA	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	MipA
k59_345743_1	1088721.NSU_4947	1.29e-109	324.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2TRX0@28211|Alphaproteobacteria,2K3CJ@204457|Sphingomonadales	204457|Sphingomonadales	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_657697_1	1267534.KB906756_gene140	5.83e-14	77.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y2YM@57723|Acidobacteria,2JKAC@204432|Acidobacteriia	204432|Acidobacteriia	K	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_17
k59_1168450_1	1424334.W822_18500	8.88e-69	229.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,3T558@506|Alcaligenaceae	28216|Betaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_70165_1	933262.AXAM01000019_gene1100	4.15e-48	165.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2WIP2@28221|Deltaproteobacteria,2MIE9@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1624	RibD_C,dCMP_cyt_deam_1
k59_70165_2	96561.Dole_2078	1.76e-09	57.4	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,2MJM4@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_1168475_1	1122137.AQXF01000007_gene3497	9e-69	222.0	COG0845@1|root,COG0845@2|Bacteria,1NGI2@1224|Proteobacteria,2U1S9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
k59_973103_1	1227360.C176_12478	7.46e-22	88.6	2EI5I@1|root,33BWX@2|Bacteria,1W0I2@1239|Firmicutes,4HYE0@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_854159_1	631362.Thi970DRAFT_04444	1.22e-136	402.0	COG3464@1|root,COG3464@2|Bacteria,1N5CJ@1224|Proteobacteria,1T4WB@1236|Gammaproteobacteria,1WZSX@135613|Chromatiales	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_230268_1	196367.JNFG01000207_gene32	3.24e-17	86.7	COG0457@1|root,COG0745@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2VHBT@28216|Betaproteobacteria,1K4NQ@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_8,Trans_reg_C
k59_267715_1	1510531.JQJJ01000010_gene2058	1.96e-06	52.8	COG0457@1|root,COG0457@2|Bacteria,1N0DE@1224|Proteobacteria,2UCGA@28211|Alphaproteobacteria,3JTSW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	MA20_05980	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
k59_306580_1	159087.Daro_3988	9.39e-187	535.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2VJ52@28216|Betaproteobacteria,2KV5T@206389|Rhodocyclales	206389|Rhodocyclales	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_112722_1	933262.AXAM01000069_gene2687	6.45e-48	173.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MIBK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
k59_973128_1	530564.Psta_4511	4.18e-21	95.9	COG0399@1|root,COG0399@2|Bacteria,2IXAP@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
k59_112728_1	268747.Q58LA1_BPPRS	3.17e-25	101.0	4QCHF@10239|Viruses,4QW57@35237|dsDNA viruses  no RNA stage,4QPIH@28883|Caudovirales,4QHVS@10662|Myoviridae	10662|Myoviridae	S	PhoH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_70231_1	1089544.KB912942_gene625	2.09e-09	63.5	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4DXQN@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE34	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_345809_2	1121935.AQXX01000122_gene5683	3.98e-33	125.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1XH4R@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
k59_736910_1	1089552.KI911559_gene2275	1.94e-05	46.2	COG0559@1|root,COG0559@2|Bacteria,1R23K@1224|Proteobacteria,2TV24@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
k59_736910_2	1366050.N234_01090	9.58e-44	154.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2WEZH@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_813895_1	1046724.KB889877_gene1529	2.17e-24	108.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,4643B@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	peptidylprolyl isomerase	ppiD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
k59_31433_1	1267005.KB911258_gene363	6.35e-102	320.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,3N61H@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	penicillin-binding protein	pbp	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
k59_657792_1	1121405.dsmv_0087	4.29e-78	249.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2MI2W@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_657803_1	243233.MCA1545	3.76e-77	257.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1XE0B@135618|Methylococcales	135618|Methylococcales	H	Vitamin B12 dependent methionine synthase, activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_1168567_1	1121403.AUCV01000031_gene2857	3.27e-44	162.0	29GCA@1|root,303A5@2|Bacteria,1NC46@1224|Proteobacteria,431AV@68525|delta/epsilon subdivisions,2WWN5@28221|Deltaproteobacteria,2MNY5@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1129135_1	1105367.CG50_00515	1.55e-69	230.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_580646_1	278957.ABEA03000176_gene2841	1.03e-07	56.2	COG1999@1|root,COG1999@2|Bacteria,46W2T@74201|Verrucomicrobia,3K80B@414999|Opitutae	414999|Opitutae	S	Copper binding periplasmic protein CusF	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
k59_580646_2	1123518.ARWI01000001_gene1635	2.23e-32	126.0	COG2010@1|root,COG2010@2|Bacteria,1R4K1@1224|Proteobacteria,1T01Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Peripla_BP_6
k59_31465_1	765912.Thimo_1012	3.93e-49	164.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1WXZW@135613|Chromatiales	135613|Chromatiales	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
k59_31465_2	1535422.ND16A_2092	8.5e-37	126.0	COG2963@1|root,COG2963@2|Bacteria,1N4WN@1224|Proteobacteria,1SAJE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2963 Transposase and inactivated derivatives	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_893972_1	9555.ENSPANP00000014797	1.64e-235	649.0	COG0039@1|root,KOG1495@2759|Eukaryota,38G9C@33154|Opisthokonta,3BGT7@33208|Metazoa,3CW73@33213|Bilateria,484IM@7711|Chordata,493KD@7742|Vertebrata,3J7F8@40674|Mammalia,35J8C@314146|Euarchontoglires,4MBN3@9443|Primates,36445@314294|Cercopithecoidea	33208|Metazoa	C	L-lactate dehydrogenase	LDHB	GO:0000166,GO:0000768,GO:0003674,GO:0003824,GO:0004457,GO:0004459,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006089,GO:0006090,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006949,GO:0007520,GO:0007525,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009653,GO:0009987,GO:0014902,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019244,GO:0019249,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0019899,GO:0019900,GO:0030154,GO:0032502,GO:0032787,GO:0034641,GO:0036094,GO:0042692,GO:0042802,GO:0043209,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0045121,GO:0046394,GO:0046483,GO:0046496,GO:0048037,GO:0048646,GO:0048856,GO:0048869,GO:0050662,GO:0051146,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0061061,GO:0071704,GO:0072330,GO:0072524,GO:0097159,GO:0098589,GO:0098805,GO:0098857,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901615,GO:1901617	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
k59_657857_1	589865.DaAHT2_2339	7.09e-105	319.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,42M2C@68525|delta/epsilon subdivisions,2WIVE@28221|Deltaproteobacteria,2MJD6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
k59_112789_1	335543.Sfum_1590	1.32e-09	60.1	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2MR5R@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
k59_1129167_1	1232410.KI421421_gene3632	5.6e-24	98.2	COG0656@1|root,COG0656@2|Bacteria	2|Bacteria	S	aldo-keto reductase (NADP) activity	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
k59_1129167_2	1121374.KB891585_gene1909	4.76e-27	105.0	COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane protein domain	VP2641	-	-	-	-	-	-	-	-	-	-	-	RDD
k59_854292_1	666681.M301_0096	3.35e-23	93.6	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,2KN3W@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
k59_1016376_1	89187.ISM_16440	1.3e-05	46.6	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2TRCD@28211|Alphaproteobacteria,46QAI@74030|Roseovarius	28211|Alphaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_1016376_2	243233.MCA1094	3.96e-104	308.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1XEBB@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
k59_1089054_1	667014.Thein_1152	2.08e-62	202.0	COG0492@1|root,COG0492@2|Bacteria,2GHK3@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
k59_213470_2	365044.Pnap_0051	3.65e-11	60.5	COG2104@1|root,COG2104@2|Bacteria,1N9VX@1224|Proteobacteria,2VVYE@28216|Betaproteobacteria,4AFRB@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM thiamineS protein	-	-	-	-	-	-	-	-	-	-	-	-	ThiS,Ub-Mut7C
k59_448314_1	76114.ebA5132	7.37e-12	64.3	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,2KVRX@206389|Rhodocyclales	206389|Rhodocyclales	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
k59_174297_1	1232437.KL661965_gene3264	1.24e-44	157.0	COG4819@1|root,COG4819@2|Bacteria,1PPGT@1224|Proteobacteria,42WP6@68525|delta/epsilon subdivisions,2WSCA@28221|Deltaproteobacteria,2MNZT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Ethanolamine utilisation protein EutA	-	-	-	-	-	-	-	-	-	-	-	-	EutA
k59_17131_1	713586.KB900536_gene154	2.26e-55	178.0	COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,1WZIV@135613|Chromatiales	135613|Chromatiales	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
k59_840120_1	3055.EDP09766	2.99e-50	170.0	COG1028@1|root,KOG0725@2759|Eukaryota,37YA7@33090|Viridiplantae,34JFV@3041|Chlorophyta	3041|Chlorophyta	Q	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_174307_1	1307759.JOMJ01000003_gene217	2.73e-26	102.0	2A45A@1|root,30SQC@2|Bacteria,1Q8WU@1224|Proteobacteria,4361I@68525|delta/epsilon subdivisions,2X0J4@28221|Deltaproteobacteria,2MCHU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM UspA	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_174310_1	552811.Dehly_1516	2.63e-63	216.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi	200795|Chloroflexi	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
k59_487674_2	1379281.AVAG01000016_gene969	1.9e-47	158.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WQFN@28221|Deltaproteobacteria,2M92T@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,POR
k59_1000479_1	96561.Dole_2392	1.01e-91	288.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1P0U1@1224|Proteobacteria,42PTP@68525|delta/epsilon subdivisions,2WJ8U@28221|Deltaproteobacteria,2MIQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_174311_1	317936.Nos7107_2202	1.21e-65	216.0	COG0402@1|root,COG0402@2|Bacteria,1GCK3@1117|Cyanobacteria,1HS6K@1161|Nostocales	1117|Cyanobacteria	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_683551_1	335543.Sfum_2961	8.43e-86	268.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria,2MQBT@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_134668_1	1535422.ND16A_0740	2.44e-97	296.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,2Q7EB@267889|Colwelliaceae	1236|Gammaproteobacteria	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
k59_330727_1	1121405.dsmv_0409	8.41e-24	92.4	2EDKE@1|root,337G8@2|Bacteria,1NDN5@1224|Proteobacteria,42WHK@68525|delta/epsilon subdivisions,2WS4A@28221|Deltaproteobacteria,2MKUW@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_292156_1	1111732.AZOD01000004_gene990	3.23e-21	92.4	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,1X3G9@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_487715_1	335543.Sfum_0771	1.06e-30	112.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,42SJ8@68525|delta/epsilon subdivisions,2WP5B@28221|Deltaproteobacteria,2MQHT@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
k59_487715_2	56780.SYN_01729	7.39e-19	87.4	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2MQYK@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_1000532_1	118797.XP_007446258.1	1.85e-138	392.0	COG1100@1|root,KOG0393@2759|Eukaryota,38B7E@33154|Opisthokonta,3BG87@33208|Metazoa,3CUE7@33213|Bilateria,487IV@7711|Chordata,48ZSV@7742|Vertebrata,3J7I7@40674|Mammalia,4IZNZ@91561|Cetartiodactyla	33208|Metazoa	U	ras homolog family member A	RHOA	GO:0000003,GO:0000166,GO:0000226,GO:0000278,GO:0000280,GO:0000281,GO:0000902,GO:0000904,GO:0000910,GO:0000912,GO:0000915,GO:0001501,GO:0001503,GO:0001505,GO:0001654,GO:0001655,GO:0001667,GO:0001700,GO:0001703,GO:0001736,GO:0001738,GO:0001745,GO:0001775,GO:0001882,GO:0001883,GO:0001932,GO:0001934,GO:0001952,GO:0001956,GO:0002009,GO:0002011,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0002237,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002520,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0003006,GO:0003158,GO:0003159,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005783,GO:0005789,GO:0005829,GO:0005886,GO:0005911,GO:0005938,GO:0006464,GO:0006508,GO:0006582,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006897,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007043,GO:0007049,GO:0007051,GO:0007052,GO:0007154,GO:0007162,GO:0007163,GO:0007164,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007173,GO:0007178,GO:0007179,GO:0007186,GO:0007264,GO:0007265,GO:0007266,GO:0007267,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007349,GO:0007368,GO:0007369,GO:0007370,GO:0007374,GO:0007377,GO:0007389,GO:0007391,GO:0007392,GO:0007395,GO:0007399,GO:0007405,GO:0007409,GO:0007411,GO:0007422,GO:0007423,GO:0007424,GO:0007431,GO:0007435,GO:0007442,GO:0007443,GO:0007444,GO:0007472,GO:0007476,GO:0007478,GO:0007480,GO:0007552,GO:0007560,GO:0008037,GO:0008038,GO:0008045,GO:0008092,GO:0008104,GO:0008150,GO:0008152,GO:0008283,GO:0008347,GO:0008360,GO:0008361,GO:0008544,GO:0009605,GO:0009607,GO:0009611,GO:0009617,GO:0009653,GO:0009719,GO:0009790,GO:0009791,GO:0009792,GO:0009799,GO:0009826,GO:0009855,GO:0009886,GO:0009887,GO:0009888,GO:0009893,GO:0009898,GO:0009913,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010004,GO:0010033,GO:0010324,GO:0010562,GO:0010564,GO:0010594,GO:0010596,GO:0010604,GO:0010631,GO:0010632,GO:0010633,GO:0010638,GO:0010646,GO:0010647,GO:0010648,GO:0010720,GO:0010721,GO:0010769,GO:0010770,GO:0010771,GO:0010810,GO:0010812,GO:0010817,GO:0010830,GO:0010927,GO:0010941,GO:0010975,GO:0010976,GO:0010977,GO:0012505,GO:0012506,GO:0014056,GO:0014057,GO:0014866,GO:0016020,GO:0016043,GO:0016049,GO:0016055,GO:0016192,GO:0016197,GO:0016331,GO:0016358,GO:0016462,GO:0016476,GO:0016477,GO:0016525,GO:0016579,GO:0016787,GO:0016817,GO:0016818,GO:0017022,GO:0017076,GO:0017111,GO:0018958,GO:0019001,GO:0019220,GO:0019222,GO:0019538,GO:0019748,GO:0019897,GO:0019898,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0021700,GO:0022008,GO:0022402,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022612,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030010,GO:0030011,GO:0030027,GO:0030029,GO:0030030,GO:0030036,GO:0030038,GO:0030048,GO:0030054,GO:0030097,GO:0030111,GO:0030141,GO:0030154,GO:0030155,GO:0030178,GO:0030182,GO:0030239,GO:0030241,GO:0030334,GO:0030335,GO:0030336,GO:0030425,GO:0030588,GO:0030589,GO:0030659,GO:0030667,GO:0030707,GO:0030855,GO:0030859,GO:0030865,GO:0030866,GO:0030950,GO:0030952,GO:0031032,GO:0031033,GO:0031034,GO:0031090,GO:0031175,GO:0031234,GO:0031252,GO:0031323,GO:0031325,GO:0031344,GO:0031345,GO:0031346,GO:0031399,GO:0031401,GO:0031410,GO:0031532,GO:0031982,GO:0031984,GO:0032153,GO:0032154,GO:0032155,GO:0032222,GO:0032224,GO:0032231,GO:0032233,GO:0032268,GO:0032270,GO:0032456,GO:0032465,GO:0032467,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032506,GO:0032535,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0032879,GO:0032940,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0033036,GO:0033043,GO:0033674,GO:0033688,GO:0033993,GO:0034097,GO:0034329,GO:0034330,GO:0034331,GO:0034332,GO:0034334,GO:0034613,GO:0034622,GO:0035006,GO:0035023,GO:0035026,GO:0035088,GO:0035089,GO:0035090,GO:0035099,GO:0035107,GO:0035114,GO:0035120,GO:0035148,GO:0035149,GO:0035150,GO:0035151,GO:0035152,GO:0035159,GO:0035162,GO:0035218,GO:0035220,GO:0035239,GO:0035272,GO:0035277,GO:0035295,GO:0035298,GO:0035315,GO:0035316,GO:0035317,GO:0035385,GO:0035556,GO:0035567,GO:0035639,GO:0036089,GO:0036094,GO:0036211,GO:0036230,GO:0036342,GO:0036477,GO:0038027,GO:0038127,GO:0040001,GO:0040007,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0042060,GO:0042063,GO:0042074,GO:0042119,GO:0042127,GO:0042175,GO:0042221,GO:0042249,GO:0042325,GO:0042327,GO:0042330,GO:0042440,GO:0042692,GO:0042752,GO:0042981,GO:0042995,GO:0043005,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043122,GO:0043123,GO:0043149,GO:0043167,GO:0043168,GO:0043170,GO:0043197,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043269,GO:0043270,GO:0043296,GO:0043297,GO:0043299,GO:0043312,GO:0043412,GO:0043535,GO:0043537,GO:0043542,GO:0043549,GO:0043583,GO:0043931,GO:0043933,GO:0043954,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044291,GO:0044309,GO:0044319,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044448,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044837,GO:0045055,GO:0045087,GO:0045177,GO:0045179,GO:0045184,GO:0045197,GO:0045198,GO:0045199,GO:0045202,GO:0045216,GO:0045321,GO:0045595,GO:0045596,GO:0045597,GO:0045664,GO:0045665,GO:0045666,GO:0045765,GO:0045787,GO:0045792,GO:0045859,GO:0045860,GO:0045937,GO:0045995,GO:0046578,GO:0046663,GO:0046883,GO:0046887,GO:0046903,GO:0046907,GO:0046928,GO:0048010,GO:0048013,GO:0048015,GO:0048017,GO:0048285,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048546,GO:0048563,GO:0048565,GO:0048568,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048592,GO:0048598,GO:0048609,GO:0048619,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048749,GO:0048799,GO:0048812,GO:0048813,GO:0048839,GO:0048840,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050767,GO:0050768,GO:0050769,GO:0050770,GO:0050771,GO:0050772,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050804,GO:0050806,GO:0050896,GO:0050919,GO:0051017,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051056,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051146,GO:0051147,GO:0051153,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051225,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051270,GO:0051271,GO:0051272,GO:0051293,GO:0051301,GO:0051302,GO:0051336,GO:0051338,GO:0051345,GO:0051347,GO:0051489,GO:0051492,GO:0051493,GO:0051495,GO:0051496,GO:0051588,GO:0051590,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0051781,GO:0051893,GO:0051952,GO:0051954,GO:0051960,GO:0051961,GO:0051962,GO:0055001,GO:0055002,GO:0055123,GO:0060071,GO:0060142,GO:0060191,GO:0060193,GO:0060255,GO:0060284,GO:0060341,GO:0060348,GO:0060429,GO:0060491,GO:0060541,GO:0060548,GO:0060560,GO:0060562,GO:0060571,GO:0060828,GO:0061024,GO:0061041,GO:0061061,GO:0061154,GO:0061162,GO:0061245,GO:0061326,GO:0061333,GO:0061339,GO:0061351,GO:0061383,GO:0061525,GO:0061564,GO:0061572,GO:0061640,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070252,GO:0070451,GO:0070593,GO:0070646,GO:0070647,GO:0070727,GO:0070820,GO:0070848,GO:0070887,GO:0070925,GO:0070977,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071345,GO:0071363,GO:0071396,GO:0071495,GO:0071559,GO:0071560,GO:0071688,GO:0071695,GO:0071704,GO:0071840,GO:0071896,GO:0071900,GO:0071902,GO:0071944,GO:0072001,GO:0072002,GO:0072089,GO:0080090,GO:0080134,GO:0090049,GO:0090051,GO:0090066,GO:0090068,GO:0090090,GO:0090109,GO:0090130,GO:0090132,GO:0090162,GO:0090175,GO:0090251,GO:0090254,GO:0090303,GO:0090307,GO:0090504,GO:0090505,GO:0090596,GO:0097159,GO:0097367,GO:0097435,GO:0097447,GO:0097458,GO:0097485,GO:0097498,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098590,GO:0098657,GO:0098794,GO:0098805,GO:0098827,GO:0099024,GO:0099177,GO:0099503,GO:0099568,GO:0099738,GO:0101002,GO:0101003,GO:0110020,GO:0110053,GO:0120025,GO:0120032,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0140014,GO:0198738,GO:1901222,GO:1901224,GO:1901265,GO:1901342,GO:1901343,GO:1901360,GO:1901363,GO:1901564,GO:1901615,GO:1901700,GO:1901701,GO:1901739,GO:1901888,GO:1902407,GO:1902410,GO:1902414,GO:1902531,GO:1902533,GO:1902766,GO:1902850,GO:1902903,GO:1902905,GO:1903034,GO:1903036,GO:1903047,GO:1903391,GO:1903475,GO:1903530,GO:1903532,GO:1903670,GO:1903671,GO:1903673,GO:1904059,GO:1905114,GO:1905330,GO:1990868,GO:1990869,GO:2000026,GO:2000027,GO:2000145,GO:2000146,GO:2000147,GO:2000181,GO:2000401,GO:2000403,GO:2000404,GO:2000406,GO:2001023,GO:2001025	-	ko:K04513,ko:K07857	ko04011,ko04014,ko04015,ko04022,ko04024,ko04062,ko04071,ko04072,ko04144,ko04150,ko04270,ko04310,ko04350,ko04360,ko04510,ko04520,ko04530,ko04611,ko04621,ko04660,ko04670,ko04722,ko04810,ko04921,ko04972,ko05100,ko05130,ko05133,ko05152,ko05200,ko05203,ko05205,ko05206,ko05210,ko05418,map04011,map04014,map04015,map04022,map04024,map04062,map04071,map04072,map04144,map04150,map04270,map04310,map04350,map04360,map04510,map04520,map04530,map04611,map04621,map04660,map04670,map04722,map04810,map04921,map04972,map05100,map05130,map05133,map05152,map05200,map05203,map05205,map05206,map05210,map05418	-	-	-	ko00000,ko00001,ko04031,ko04131,ko04147	-	-	-	Ras
k59_412117_2	1114922.CIFAM_17_02100	3.17e-103	312.0	COG3547@1|root,COG3547@2|Bacteria,1QYJU@1224|Proteobacteria,1RN0A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_723013_1	1007096.BAGW01000016_gene987	3.22e-35	130.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,2N8CS@216572|Oscillospiraceae	186801|Clostridia	M	GDP-mannose 4,6 dehydratase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_605634_1	1461694.ATO9_10665	2.77e-58	191.0	28KEA@1|root,2ZA0J@2|Bacteria,1R5TS@1224|Proteobacteria,2U48U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Sulfotransferase domain	-	-	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
k59_487736_1	1123372.AUIT01000024_gene1097	1e-18	90.9	COG0685@1|root,COG2069@1|root,COG0685@2|Bacteria,COG2069@2|Bacteria,2GHER@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	CE	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
k59_292193_1	1265505.ATUG01000002_gene1098	1.1e-60	200.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,2MP6C@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
k59_1193081_1	265072.Mfla_0734	1.34e-53	183.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,2KKDQ@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_487760_1	1121468.AUBR01000005_gene53	5.53e-49	168.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,42EX3@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
k59_448414_1	555779.Dthio_PD2105	2.74e-53	181.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,43B03@68525|delta/epsilon subdivisions,2X6E6@28221|Deltaproteobacteria,2MH1Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_252880_1	366394.Smed_6258	4.66e-107	318.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,4BC2J@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase and inactivated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
k59_917925_1	384765.SIAM614_02596	5.66e-91	285.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_134747_1	1121448.DGI_2643	6.29e-108	325.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,43EAS@68525|delta/epsilon subdivisions,2X7TI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_292236_1	1322246.BN4_20215	8.45e-75	231.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,435K3@68525|delta/epsilon subdivisions,2X9AV@28221|Deltaproteobacteria,2M8KU@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
k59_174461_2	472759.Nhal_1619	5.96e-22	96.3	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria,1X01G@135613|Chromatiales	135613|Chromatiales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1235152_1	1121121.KB894319_gene3833	4.28e-08	58.5	COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,4H9RC@91061|Bacilli,274Y8@186822|Paenibacillaceae	91061|Bacilli	K	YsiA-like protein, C-terminal region	fadR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
k59_761657_1	2045.KR76_09290	3.53e-48	163.0	COG2816@1|root,COG2816@2|Bacteria,2GJZY@201174|Actinobacteria,4DN72@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
k59_761657_2	866536.Belba_1625	5.15e-45	155.0	COG3332@1|root,COG3332@2|Bacteria,4NMX4@976|Bacteroidetes,47P76@768503|Cytophagia	976|Bacteroidetes	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
k59_840240_1	247490.KSU1_A0020	2.99e-36	140.0	COG0761@1|root,COG0761@2|Bacteria,2IXK4@203682|Planctomycetes	203682|Planctomycetes	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB,UbiA
k59_448451_2	647113.Metok_0603	2.56e-07	55.8	COG1397@1|root,arCOG04448@2157|Archaea,2XV15@28890|Euryarchaeota,23QAK@183939|Methanococci	183939|Methanococci	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
k59_292262_1	469383.Cwoe_4939	3.99e-64	212.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C,ECH_1
k59_566071_1	504832.OCAR_4230	9.4e-106	315.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2TSVJ@28211|Alphaproteobacteria,3JSKB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
k59_1000673_1	760192.Halhy_4258	0.000217	50.1	COG0501@1|root,COG0501@2|Bacteria,4PP1T@976|Bacteroidetes,1J0XG@117747|Sphingobacteriia	976|Bacteroidetes	O	Zn-dependent protease contains TPR repeats	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_252954_1	1335757.SPICUR_03195	3.21e-66	218.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1WW1H@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_330875_1	1123057.P872_04760	2.25e-40	152.0	COG3291@1|root,COG5498@1|root,COG3291@2|Bacteria,COG5498@2|Bacteria,4PPR2@976|Bacteroidetes,47YQN@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1000704_1	3694.POPTR_0015s09810.1	6.6e-14	72.0	KOG0118@1|root,KOG0118@2759|Eukaryota,37MBR@33090|Viridiplantae,3GC3A@35493|Streptophyta,4JJA9@91835|fabids	35493|Streptophyta	A	kDa ribonucleoprotein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K11294	ko05130,map05130	-	-	-	ko00000,ko00001,ko03009,ko03036	-	-	-	RRM_1
k59_840313_1	1121405.dsmv_1433	5.01e-49	166.0	COG0382@1|root,COG0382@2|Bacteria,1RA0E@1224|Proteobacteria,42QUB@68525|delta/epsilon subdivisions,2WMY2@28221|Deltaproteobacteria,2MJY3@213118|Desulfobacterales	28221|Deltaproteobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
k59_1074900_1	1111069.TCCBUS3UF1_17120	9.72e-08	56.6	COG0664@1|root,COG0664@2|Bacteria,1WJXH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
k59_1074900_2	1121405.dsmv_0565	5.42e-27	108.0	COG0057@1|root,COG0057@2|Bacteria,1R8ZT@1224|Proteobacteria,42PY6@68525|delta/epsilon subdivisions,2WKEI@28221|Deltaproteobacteria,2MII4@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_761734_1	1298867.AUES01000001_gene1663	5.97e-60	196.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,2TR29@28211|Alphaproteobacteria,3K2MT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class I and II	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_412308_1	1265313.HRUBRA_00627	1.19e-175	506.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,1RMGS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	alkK	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
k59_56205_1	1232437.KL661978_gene3774	2.32e-56	187.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2MIAD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_1074912_2	1026882.MAMP_01646	1.06e-35	136.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,4604W@72273|Thiotrichales	72273|Thiotrichales	D	cell division protein	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_918047_1	177437.HRM2_41690	3.87e-42	151.0	COG4671@1|root,COG4671@2|Bacteria,1NE6T@1224|Proteobacteria,42M07@68525|delta/epsilon subdivisions,2WJA3@28221|Deltaproteobacteria,2MHTF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k59_370732_1	27679.XP_010347480.1	2.14e-110	340.0	KOG1995@1|root,KOG1995@2759|Eukaryota,38XGM@33154|Opisthokonta,3BFW0@33208|Metazoa,3D2IB@33213|Bilateria,47ZR0@7711|Chordata,491FS@7742|Vertebrata,3J93P@40674|Mammalia,35HPU@314146|Euarchontoglires,4M70T@9443|Primates	33208|Metazoa	A	Zn-finger in Ran binding protein and others	EWSR1	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0031974,GO:0031981,GO:0042802,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0070013	-	ko:K13098,ko:K13209	ko05202,map05202	-	-	-	ko00000,ko00001,ko03041	-	-	-	RRM_1,zf-RanBP
k59_605830_1	61853.ENSNLEP00000022555	5.94e-141	403.0	COG2163@1|root,KOG1694@2759|Eukaryota,39HUD@33154|Opisthokonta,3BGDM@33208|Metazoa,3D11N@33213|Bilateria,482HA@7711|Chordata,48YX0@7742|Vertebrata,3J226@40674|Mammalia,35FEF@314146|Euarchontoglires,4MCNG@9443|Primates	33208|Metazoa	J	Belongs to the eukaryotic ribosomal protein eL6 family	RPL6	GO:0000027,GO:0000049,GO:0000184,GO:0000956,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005783,GO:0005789,GO:0005791,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006355,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007275,GO:0007568,GO:0008104,GO:0008150,GO:0008152,GO:0008340,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009889,GO:0009892,GO:0009987,GO:0010259,GO:0010467,GO:0010468,GO:0010556,GO:0010605,GO:0010629,GO:0012505,GO:0015031,GO:0015833,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019219,GO:0019222,GO:0019439,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030016,GO:0030017,GO:0030867,GO:0031090,GO:0031323,GO:0031326,GO:0031672,GO:0031974,GO:0031981,GO:0031984,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034655,GO:0035770,GO:0036464,GO:0042175,GO:0042254,GO:0042255,GO:0042273,GO:0042788,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044445,GO:0044446,GO:0044449,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0048856,GO:0050789,GO:0050794,GO:0051171,GO:0051179,GO:0051234,GO:0051252,GO:0051641,GO:0051649,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0070727,GO:0070925,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071826,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0080090,GO:0090150,GO:0090304,GO:0097159,GO:0098552,GO:0098554,GO:0098556,GO:0098562,GO:0098588,GO:0098827,GO:0099080,GO:0099081,GO:0099512,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903506,GO:1990904,GO:1990932,GO:2000112,GO:2001141	-	ko:K02934	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6e,Ribosomal_L6e_N
k59_566171_1	1211115.ALIQ01000118_gene4577	3.93e-90	274.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TRA8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	coxM	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
k59_1000796_1	1348657.M622_14795	9.1e-69	220.0	COG0075@1|root,COG0075@2|Bacteria,1PM38@1224|Proteobacteria,2VHNM@28216|Betaproteobacteria,2KVAR@206389|Rhodocyclales	206389|Rhodocyclales	E	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_1000796_2	1127673.GLIP_0983	4.84e-08	52.8	COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,1RZZS@1236|Gammaproteobacteria,4666H@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_C_2,GST_N_3
k59_1039864_1	335543.Sfum_1977	1.67e-147	446.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_644234_1	706587.Desti_0416	1.01e-85	276.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.5	ko:K20447	ko00760,ko01120,map00760,map01120	-	R01720	RC00589	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_56280_1	880072.Desac_1453	7.56e-78	239.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,2MR4Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_253074_1	118163.Ple7327_3451	1.61e-33	117.0	COG3450@1|root,COG3450@2|Bacteria,1G7YR@1117|Cyanobacteria,3VMXP@52604|Pleurocapsales	1117|Cyanobacteria	S	enzyme of the cupin superfamily	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
k59_253074_2	243231.GSU2792	1.65e-43	150.0	COG0500@1|root,COG0500@2|Bacteria,1QW0F@1224|Proteobacteria,43C56@68525|delta/epsilon subdivisions,2X7FJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_683828_1	686340.Metal_1558	1.89e-166	476.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1XEUJ@135618|Methylococcales	135618|Methylococcales	C	Isocitrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
k59_918108_1	146922.JOFU01000010_gene1484	4.23e-08	57.0	COG3447@1|root,COG3447@2|Bacteria,2GJB0@201174|Actinobacteria	201174|Actinobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MASE1,SpoIIE
k59_56305_1	194439.CT0946	1.51e-12	67.4	COG2038@1|root,COG2038@2|Bacteria,1FD5I@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
k59_56305_2	1304284.L21TH_1560	3.79e-20	87.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,36KXJ@31979|Clostridiaceae	186801|Clostridia	H	cobinamide kinase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
k59_412468_1	1120956.JHZK01000006_gene697	2.34e-50	172.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TSCR@28211|Alphaproteobacteria,1JNN1@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_412468_2	1282876.BAOK01000001_gene2274	2.58e-61	191.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,4BQ9M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the P(II) protein family	glnB	GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_761871_1	9555.ENSPANP00000014320	1.82e-173	484.0	COG0638@1|root,KOG0178@2759|Eukaryota,38HA3@33154|Opisthokonta,3BAA5@33208|Metazoa,3CSJU@33213|Bilateria,47ZIS@7711|Chordata,48ZUT@7742|Vertebrata,3JD6Z@40674|Mammalia,3591A@314146|Euarchontoglires,4MEJ5@9443|Primates,35W4Q@314294|Cercopithecoidea	33208|Metazoa	O	subunit alpha	PSMA4	GO:0000502,GO:0000932,GO:0001673,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005839,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016579,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0031974,GO:0031981,GO:0032991,GO:0035770,GO:0036211,GO:0036464,GO:0043073,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0051603,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369,GO:1990904	3.4.25.1	ko:K02728	ko03050,map03050	M00337,M00340	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
k59_1114881_1	754436.JCM19237_6148	7.82e-32	129.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1N17V@1224|Proteobacteria,1RNG1@1236|Gammaproteobacteria,1XV2R@135623|Vibrionales	135623|Vibrionales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HK_sensor,HisKA
k59_97017_1	506534.Rhein_1775	1.73e-16	85.9	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales	135613|Chromatiales	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_840457_1	1403819.BATR01000137_gene4864	1.69e-42	153.0	2ECB1@1|root,3369C@2|Bacteria,46WPZ@74201|Verrucomicrobia,2IW2Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_174759_1	1415778.JQMM01000001_gene1034	1.69e-60	196.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,1J600@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	metal-dependent phosphoesterases (PHP family)	trpH	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
k59_1196029_4	1121441.AUCX01000008_gene2276	8.29e-09	60.5	COG4388@1|root,COG4388@2|Bacteria,1R5B8@1224|Proteobacteria,43B2G@68525|delta/epsilon subdivisions,2X6GH@28221|Deltaproteobacteria,2MC8J@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1042096_1	1384054.N790_09220	9.59e-139	407.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,1RNGQ@1236|Gammaproteobacteria,1X482@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
k59_416049_1	177437.HRM2_04890	5.62e-69	222.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,42NTX@68525|delta/epsilon subdivisions,2WMFG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	sarcosine oxidase	soxB	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
k59_451234_1	1415778.JQMM01000001_gene792	3.8e-92	298.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1J8QV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_530778_1	59374.Fisuc_2493	2.51e-69	228.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_217542_1	1158756.AQXQ01000009_gene1216	1.92e-53	179.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1WW93@135613|Chromatiales	135613|Chromatiales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_327667_2	1279017.AQYJ01000011_gene3050	6.95e-32	124.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,467TT@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
k59_602448_1	519989.ECTPHS_14156	2.98e-42	144.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,1RSJY@1236|Gammaproteobacteria,1WY4B@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
k59_837096_2	1122611.KB904018_gene6879	3.62e-07	59.3	2DRUH@1|root,33D46@2|Bacteria,2GKXS@201174|Actinobacteria,4EFNM@85012|Streptosporangiales	201174|Actinobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
k59_53203_1	926692.AZYG01000085_gene856	1.2e-82	259.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,249HN@186801|Clostridia,3WA8E@53433|Halanaerobiales	186801|Clostridia	L	Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_1111555_1	414684.RC1_1820	1.02e-13	75.1	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TUXY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EU	peptidase S9	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
k59_602476_1	1121878.AUGL01000009_gene3301	4.48e-53	179.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_954772_1	9555.ENSPANP00000015165	8.78e-134	384.0	COG5040@1|root,KOG0841@2759|Eukaryota,38CKG@33154|Opisthokonta,3BCFK@33208|Metazoa,3CT6T@33213|Bilateria,486HK@7711|Chordata,48VRN@7742|Vertebrata,3J1VR@40674|Mammalia,35KPZ@314146|Euarchontoglires,4MA1G@9443|Primates,35XXE@314294|Cercopithecoidea	33208|Metazoa	O	Belongs to the 14-3-3 family	YWHAZ	GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0031410,GO:0031982,GO:0042470,GO:0043226,GO:0043227,GO:0043229,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0048770,GO:0097708	-	ko:K16197	ko04013,ko04110,ko04114,ko04151,ko04212,ko04390,ko04391,ko05161,ko05169,ko05203,map04013,map04110,map04114,map04151,map04212,map04390,map04391,map05161,map05169,map05203	-	-	-	ko00000,ko00001,ko03400,ko04147	-	-	-	14-3-3
k59_1231409_1	1340493.JNIF01000004_gene1118	4.33e-78	243.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_288949_1	743721.Psesu_1674	3.7e-54	178.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria,1X4JP@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA
k59_210331_1	1121456.ATVA01000011_gene1357	5.98e-56	195.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WJKV@28221|Deltaproteobacteria,2M7VM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_14299_1	633149.Bresu_2687	8.28e-11	66.6	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1N7IE@1224|Proteobacteria,2TVJS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_641207_1	1304885.AUEY01000036_gene2247	7.34e-101	309.0	COG0591@1|root,COG0591@2|Bacteria,1PNHU@1224|Proteobacteria,43AQ2@68525|delta/epsilon subdivisions,2X63U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_249742_1	483219.LILAB_32190	2.48e-55	182.0	COG4974@1|root,COG4974@2|Bacteria,1RC0C@1224|Proteobacteria,42W1W@68525|delta/epsilon subdivisions,2WRTZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
k59_720161_1	1234595.C725_2575	1.24e-32	125.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2TSM0@28211|Alphaproteobacteria,4BPSI@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
k59_14349_1	1232683.ADIMK_0488	3.63e-78	248.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,1RZBX@1236|Gammaproteobacteria,469JC@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_210396_1	1121405.dsmv_0564	2.39e-64	221.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MXBU@1224|Proteobacteria,42M59@68525|delta/epsilon subdivisions,2WIUK@28221|Deltaproteobacteria,2MICN@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_171142_1	1394178.AWOO02000015_gene7052	1.74e-28	114.0	COG1028@1|root,COG1028@2|Bacteria,2GYE3@201174|Actinobacteria,4EMEX@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_367540_1	933262.AXAM01000003_gene2802	1.2e-60	209.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2WJBN@28221|Deltaproteobacteria,2MI4C@213118|Desulfobacterales	28221|Deltaproteobacteria	J	CBS domain	ccaA	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
k59_131903_1	1232410.KI421422_gene2071	3.74e-90	288.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,43S73@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_367543_1	1116375.VEJY3_00545	1.4e-05	48.1	2E42P@1|root,32YZ5@2|Bacteria,1N868@1224|Proteobacteria,1TAFS@1236|Gammaproteobacteria,1XUT4@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF4124)	VP0120	-	-	-	-	-	-	-	-	-	-	-	DUF4124
k59_367543_2	314278.NB231_10959	1.05e-62	205.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1WVZ2@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_14379_2	1121935.AQXX01000095_gene2582	6.47e-28	112.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria	1224|Proteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483,ko:K11183	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
k59_954917_1	1123242.JH636435_gene1115	4.46e-91	276.0	COG1082@1|root,COG1082@2|Bacteria,2IXXS@203682|Planctomycetes	203682|Planctomycetes	G	PFAM AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
k59_996661_1	1121405.dsmv_1991	4.23e-99	299.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
k59_720224_2	1123073.KB899241_gene3507	8.07e-12	67.8	COG1524@1|root,COG1524@2|Bacteria,1PR75@1224|Proteobacteria,1RZUP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
k59_93766_1	1123371.ATXH01000017_gene670	9.46e-69	227.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,2GGWQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,dCache_1
k59_996699_1	290317.Cpha266_2139	1.71e-69	222.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_33
k59_93783_2	935261.JAGL01000006_gene2214	1.24e-44	151.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TT8N@28211|Alphaproteobacteria,43HK8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	branched-chain amino acid	livF1	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_758773_1	85643.Tmz1t_2786	2.25e-25	107.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,2KVN9@206389|Rhodocyclales	206389|Rhodocyclales	S	Permease YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_876451_1	1121935.AQXX01000117_gene5083	7.42e-10	62.0	COG1139@1|root,COG1139@2|Bacteria,1MV6J@1224|Proteobacteria,1RQEA@1236|Gammaproteobacteria,1XHUV@135619|Oceanospirillales	135619|Oceanospirillales	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_7,Fer4_8,LUD_dom
k59_93818_1	1379281.AVAG01000032_gene119	6.46e-59	195.0	COG0438@1|root,COG0438@2|Bacteria,1R8YI@1224|Proteobacteria,42N8I@68525|delta/epsilon subdivisions,2WIYJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
k59_797668_1	485915.Dret_0857	6.96e-25	100.0	COG1418@1|root,COG1418@2|Bacteria,1RGCM@1224|Proteobacteria,42RC5@68525|delta/epsilon subdivisions,2WNBA@28221|Deltaproteobacteria,2MBBU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_797668_2	1232437.KL661978_gene3783	1.45e-31	122.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria,2MI8R@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_14455_1	977880.RALTA_A1227	2.09e-71	235.0	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,2VJ4I@28216|Betaproteobacteria,1K1BW@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Glycerol acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	Acyltransferase,MFS_1
k59_641342_1	1121875.KB907546_gene2199	2.05e-76	245.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1I2RR@117743|Flavobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_93832_1	10141.ENSCPOP00000014150	4.43e-121	353.0	COG0445@1|root,KOG2667@2759|Eukaryota,38C7Q@33154|Opisthokonta,3BIPU@33208|Metazoa,3CY2Q@33213|Bilateria,48842@7711|Chordata,49486@7742|Vertebrata,3J2TX@40674|Mammalia,35P2A@314146|Euarchontoglires,4Q6U4@9989|Rodentia	33208|Metazoa	U	Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)	ERGIC3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005793,GO:0006810,GO:0006888,GO:0008150,GO:0016192,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046907,GO:0048193,GO:0051179,GO:0051234,GO:0051641,GO:0051649	-	ko:K20367	-	-	-	-	ko00000,ko04131	-	-	-	COPIIcoated_ERV,ERGIC_N
k59_327948_1	7918.ENSLOCP00000013220	3.78e-54	189.0	COG0318@1|root,KOG1177@2759|Eukaryota,38ES8@33154|Opisthokonta,3BHR0@33208|Metazoa,3CTUM@33213|Bilateria,48AEJ@7711|Chordata,48ZGR@7742|Vertebrata,49SX8@7898|Actinopterygii	33208|Metazoa	I	acyl-CoA synthetase family member 2	ACSF2	GO:0003674,GO:0003824,GO:0003996,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_720313_1	521674.Plim_2585	9.8e-05	51.2	COG0189@1|root,COG0189@2|Bacteria,2IWYK@203682|Planctomycetes	203682|Planctomycetes	HJ	Belongs to the RimK family	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GSH-S_N,RimK
k59_408329_1	1116369.KB890024_gene1	1.43e-39	150.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2U1YP@28211|Alphaproteobacteria,43JUP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,HemolysinCabind,VWA_2
k59_955018_1	880072.Desac_2886	4.87e-30	111.0	COG0636@1|root,COG0636@2|Bacteria,1NAIE@1224|Proteobacteria,42VAI@68525|delta/epsilon subdivisions,2WRI4@28221|Deltaproteobacteria,2MQNG@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
k59_876505_1	880072.Desac_0657	8.94e-72	231.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,2MQ5B@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
k59_955025_1	1386089.N865_07860	3.52e-25	106.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4FFKZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Carboxylate--amine ligase	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
k59_837357_1	1123368.AUIS01000003_gene1821	2.23e-53	178.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,1RPZ3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
k59_445615_1	1122917.KB899672_gene753	6.93e-33	122.0	COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4HDYS@91061|Bacilli,26XVE@186822|Paenibacillaceae	91061|Bacilli	O	Peptide methionine sulfoxide reductase	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
k59_327996_1	1123371.ATXH01000043_gene808	1.12e-56	191.0	COG0612@1|root,COG0612@2|Bacteria,2GICG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_93889_1	1123368.AUIS01000009_gene2503	1.25e-18	84.7	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RN76@1236|Gammaproteobacteria,2NBW1@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_93889_2	1123392.AQWL01000001_gene1353	2.49e-63	202.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,2WH34@28216|Betaproteobacteria,1KSTU@119069|Hydrogenophilales	119069|Hydrogenophilales	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	6PGD,NAD_binding_2
k59_249987_1	523791.Kkor_0959	1.89e-55	193.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1XH3Z@135619|Oceanospirillales	135619|Oceanospirillales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
k59_408406_1	1120705.FG95_02544	1.82e-50	181.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,2TUDX@28211|Alphaproteobacteria,2K1E2@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_14545_2	1205680.CAKO01000002_gene2495	1.07e-30	121.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TU8Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,CTP_transf_3
k59_488365_2	1168065.DOK_07554	5.62e-11	68.9	COG2207@1|root,COG2207@2|Bacteria,1R7JV@1224|Proteobacteria,1S13H@1236|Gammaproteobacteria,1J5N7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k59_606321_1	243233.MCA0198	2.15e-84	259.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria,1XFSP@135618|Methylococcales	135618|Methylococcales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
k59_762281_1	1232410.KI421428_gene1227	4.9e-83	267.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,43S77@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Elongation factor G, domain IV	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_644677_1	765912.Thimo_2365	1.14e-84	278.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales	135613|Chromatiales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_1001435_1	1121439.dsat_0639	1.58e-101	318.0	COG0243@1|root,COG0243@2|Bacteria,1R5ZE@1224|Proteobacteria,42QK1@68525|delta/epsilon subdivisions,2WPX8@28221|Deltaproteobacteria,2MEF8@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_684282_1	479437.Elen_3015	1.98e-40	142.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4CUUM@84998|Coriobacteriia	84998|Coriobacteriia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_684282_2	335543.Sfum_2753	1.8e-30	117.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,42QZK@68525|delta/epsilon subdivisions,2WPP6@28221|Deltaproteobacteria,2MRV5@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_97427_2	391937.NA2_06363	5.53e-101	303.0	COG0005@1|root,COG0005@2|Bacteria,1R7BS@1224|Proteobacteria,2U4B1@28211|Alphaproteobacteria,43MN1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
k59_413045_1	1121438.JNJA01000005_gene1173	5.91e-05	46.2	COG4972@1|root,COG4972@2|Bacteria,1Q92S@1224|Proteobacteria,4362J@68525|delta/epsilon subdivisions,2X0K9@28221|Deltaproteobacteria,2MCPZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Pilus assembly protein	-	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PilN
k59_413045_2	96561.Dole_1038	2.03e-09	59.7	COG3149@1|root,COG3149@2|Bacteria,1NEZ3@1224|Proteobacteria,42WMP@68525|delta/epsilon subdivisions,2WR67@28221|Deltaproteobacteria,2MKKX@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein M	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
k59_606353_1	96561.Dole_0383	1.68e-29	121.0	COG0382@1|root,COG0761@1|root,COG0382@2|Bacteria,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,42MJK@68525|delta/epsilon subdivisions,2WJ8V@28221|Deltaproteobacteria,2MI49@213118|Desulfobacterales	28221|Deltaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,UbiA
k59_214528_1	765914.ThisiDRAFT_2796	3.7e-35	137.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,1WXIK@135613|Chromatiales	135613|Chromatiales	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
k59_135371_2	1267005.KB911257_gene991	1.63e-18	85.9	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA,Mrr_cat
k59_97501_1	582515.KR51_00033940	7.41e-30	119.0	COG0296@1|root,COG0296@2|Bacteria,1G1IW@1117|Cyanobacteria	1117|Cyanobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	iJN678.glgB	Alpha-amylase,Alpha-amylase_C,CBM_48
k59_1170115_1	748247.AZKH_2641	7.07e-43	160.0	COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,2VHM3@28216|Betaproteobacteria,2KVYH@206389|Rhodocyclales	206389|Rhodocyclales	I	Phospholipase D Active site motif	-	-	3.1.4.4	ko:K01115	ko00564,ko00565,ko01100,ko01110,ko04014,ko04024,ko04071,ko04072,ko04144,ko04666,ko04724,ko04912,ko05231,map00564,map00565,map01100,map01110,map04014,map04024,map04071,map04072,map04144,map04666,map04724,map04912,map05231	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000,ko04131	-	-	-	PLDc,SNARE_assoc
k59_659255_1	9986.ENSOCUP00000020661	1.47e-129	380.0	COG1222@1|root,KOG0727@2759|Eukaryota,39J9B@33154|Opisthokonta,3BCZC@33208|Metazoa,3CVBN@33213|Bilateria,4815Z@7711|Chordata,49222@7742|Vertebrata,3JCB5@40674|Mammalia,35GG7@314146|Euarchontoglires	33208|Metazoa	O	proteasome-activating ATPase activity	PSMC4	GO:0000502,GO:0001673,GO:0001701,GO:0001824,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005838,GO:0006355,GO:0006357,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0007275,GO:0008134,GO:0008150,GO:0008152,GO:0008540,GO:0009056,GO:0009057,GO:0009790,GO:0009792,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010498,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016234,GO:0016462,GO:0016579,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017025,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0019941,GO:0022624,GO:0030162,GO:0030163,GO:0030433,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031334,GO:0031595,GO:0031597,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032991,GO:0033554,GO:0034976,GO:0036211,GO:0036402,GO:0036503,GO:0042176,GO:0042221,GO:0042623,GO:0043009,GO:0043073,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043254,GO:0043412,GO:0043632,GO:0043687,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045202,GO:0045732,GO:0045862,GO:0045893,GO:0045898,GO:0045899,GO:0045935,GO:0045944,GO:0048518,GO:0048522,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051603,GO:0051716,GO:0060255,GO:0060260,GO:0060261,GO:0061136,GO:0065007,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0080090,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901800,GO:1902494,GO:1902680,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1903506,GO:1903508,GO:1905368,GO:1905369,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K03063	ko03050,ko05169,map03050,map05169	M00341	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA
k59_189167_1	153948.NAL212_1200	2.56e-36	140.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2VP0G@28216|Betaproteobacteria	28216|Betaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_699554_2	335543.Sfum_0614	8.64e-53	174.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
k59_699559_1	879212.DespoDRAFT_03309	2.5e-24	93.2	2DPW4@1|root,333N7@2|Bacteria	2|Bacteria	S	TIGRFAM YgiT-type zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_933558_1	706587.Desti_1062	4.88e-69	219.0	COG0524@1|root,COG0524@2|Bacteria,1QMIR@1224|Proteobacteria,42NDK@68525|delta/epsilon subdivisions,2WK15@28221|Deltaproteobacteria,2MR2Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PFAM PfkB	-	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_738476_1	981384.AEYW01000001_gene1490	2.8e-68	220.0	COG1234@1|root,COG1234@2|Bacteria,1RIJP@1224|Proteobacteria	1224|Proteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_4
k59_71740_1	349521.HCH_04166	4.61e-16	82.0	2BSEF@1|root,32MGE@2|Bacteria,1N9VN@1224|Proteobacteria,1SG8G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_855742_1	522306.CAP2UW1_2122	2.58e-27	115.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2VIKH@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	imuB	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
k59_1209492_1	1265503.KB905166_gene652	2.78e-56	196.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_231865_1	933262.AXAM01000025_gene3415	1.21e-95	293.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,2MHNX@213118|Desulfobacterales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_347383_1	185453.XP_006874764.1	4.04e-13	70.5	KOG1695@1|root,KOG1695@2759|Eukaryota,39R3B@33154|Opisthokonta,3BJH6@33208|Metazoa,3D3HE@33213|Bilateria,482XR@7711|Chordata,48YR3@7742|Vertebrata,3J8I2@40674|Mammalia,351BM@311790|Afrotheria	33208|Metazoa	O	Glutathione S-transferase, C-terminal domain	HPGDS	GO:0000287,GO:0001516,GO:0003674,GO:0003824,GO:0004364,GO:0004601,GO:0004602,GO:0004667,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006518,GO:0006575,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0006749,GO:0006790,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008285,GO:0008610,GO:0009058,GO:0009636,GO:0009987,GO:0016053,GO:0016209,GO:0016491,GO:0016684,GO:0016740,GO:0016765,GO:0016853,GO:0016860,GO:0019752,GO:0032787,GO:0033559,GO:0034641,GO:0042127,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043900,GO:0043901,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046456,GO:0046457,GO:0046872,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051239,GO:0051241,GO:0051716,GO:0055114,GO:0065007,GO:0070887,GO:0071704,GO:0072330,GO:0097237,GO:0098754,GO:0098869,GO:1901564,GO:1901568,GO:1901570,GO:1901576,GO:1905936,GO:1905937,GO:1990748,GO:2000241,GO:2000242,GO:2000254,GO:2000255	2.5.1.18,5.3.99.2	ko:K04097	ko00480,ko00590,ko00980,ko00982,ko01100,ko05204,map00480,map00590,map00980,map00982,map01100,map05204	-	R02266,R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409	RC00004,RC00069,RC00672,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000	-	-	-	GST_C_3,GST_N
k59_33036_1	1121396.KB893053_gene2383	9.53e-08	53.5	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,2MISV@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
k59_33036_2	177437.HRM2_48100	1.28e-38	139.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,2MJ27@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
k59_738500_1	999141.GME_08339	3.86e-14	72.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1XI3H@135619|Oceanospirillales	135619|Oceanospirillales	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.113	ko:K12256	ko00330,ko01100,map00330,map01100	-	R08714	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
k59_738500_2	1027273.GZ77_15080	2.24e-50	174.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,1RPNZ@1236|Gammaproteobacteria,1XHHJ@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the glutamine synthetase family	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
k59_738517_1	1121403.AUCV01000054_gene2598	1.62e-114	331.0	COG2220@1|root,COG2220@2|Bacteria,1PFZZ@1224|Proteobacteria,42SXY@68525|delta/epsilon subdivisions,2WPFM@28221|Deltaproteobacteria,2MMG4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
k59_150269_1	697282.Mettu_3067	4.27e-15	79.0	COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,1RMJV@1236|Gammaproteobacteria,1XFY9@135618|Methylococcales	135618|Methylococcales	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
k59_1130634_1	455436.DS989811_gene1624	2.69e-08	62.0	COG0642@1|root,COG0642@2|Bacteria,1QU3Z@1224|Proteobacteria,1T311@1236|Gammaproteobacteria,46D2F@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,HATPase_c,HisKA
k59_114281_1	76114.ebA6677	8.29e-37	136.0	COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,2VISX@28216|Betaproteobacteria,2KU66@206389|Rhodocyclales	206389|Rhodocyclales	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1090450_2	95619.PM1_0221865	2.19e-74	236.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
k59_738533_1	525897.Dbac_2315	5.55e-88	276.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,2M9D1@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179,ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR,POR_N,TPP_enzyme_C
k59_347420_1	713586.KB900536_gene308	1.38e-49	164.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1WYXK@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
k59_347429_1	565045.NOR51B_1884	1.3e-47	157.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,1RPA1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
k59_815586_2	313628.LNTAR_14782	1.05e-21	95.1	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	alaA	GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0040007,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.2,2.6.1.66	ko:K00814,ko:K14260	ko00220,ko00250,ko00290,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00220,map00250,map00290,map00710,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00171	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv0337c	Aminotran_1_2
k59_621818_1	1050202.KB913024_gene3640	4e-10	63.9	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,409WS@622450|Actinopolysporales	201174|Actinobacteria	S	Reductase C-terminal	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
k59_503843_1	526222.Desal_0431	7.99e-21	95.9	COG3517@1|root,COG3517@2|Bacteria,1QDFB@1224|Proteobacteria,435P2@68525|delta/epsilon subdivisions,2X02H@28221|Deltaproteobacteria,2MA18@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Type VI secretion protein, EvpB/VC_A0108, tail sheath	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA,VipB
k59_582186_2	926556.Echvi_1839	2.09e-40	149.0	COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,47K8A@768503|Cytophagia	976|Bacteroidetes	C	Monomeric isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
k59_503864_1	583345.Mmol_0661	6.52e-19	89.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,2VNXD@28216|Betaproteobacteria,2KMHI@206350|Nitrosomonadales	206350|Nitrosomonadales	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
k59_1053157_1	506534.Rhein_2236	6.09e-17	79.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1WWB2@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
k59_1053157_2	1123073.KB899242_gene1686	4.09e-49	162.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1X3DJ@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_1209559_1	1137799.GZ78_14690	3.15e-50	174.0	COG3633@1|root,COG3633@2|Bacteria,1MXE1@1224|Proteobacteria,1RP9B@1236|Gammaproteobacteria,1XIYT@135619|Oceanospirillales	135619|Oceanospirillales	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
k59_1053168_1	156889.Mmc1_0229	1.51e-70	226.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2TSYI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Phosphate	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_933682_1	445972.ANACOL_01845	1.63e-65	209.0	2CGZW@1|root,2Z7Z5@2|Bacteria,1UVRJ@1239|Firmicutes,24AW4@186801|Clostridia,3WSER@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_582220_1	207559.Dde_3104	2.14e-45	157.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42N28@68525|delta/epsilon subdivisions,2WJVR@28221|Deltaproteobacteria,2M825@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	hemU	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_582220_2	1220582.RRU01S_23_00060	1.39e-07	54.7	COG1129@1|root,COG1129@2|Bacteria,1NXEZ@1224|Proteobacteria,2U0IG@28211|Alphaproteobacteria,4B8GP@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	ABC-type sugar transport system, ATPase component	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
k59_738590_1	78245.Xaut_2828	1.07e-16	80.5	COG3247@1|root,COG3247@2|Bacteria,1RFIH@1224|Proteobacteria,2U84T@28211|Alphaproteobacteria,3EZR4@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
k59_1209574_1	519989.ECTPHS_01134	5.8e-50	176.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales	135613|Chromatiales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_933701_1	713586.KB900536_gene124	7.9e-89	289.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
k59_193137_1	391595.RLO149_c037010	1.18e-118	354.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	MA20_04810	-	3.5.1.82	ko:K01461	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_3
k59_468308_1	445683.E3SK21_9CAUD	1.3e-84	266.0	4QBAK@10239|Viruses,4QY34@35237|dsDNA viruses  no RNA stage,4QQBQ@28883|Caudovirales,4QIQI@10662|Myoviridae	10662|Myoviridae	S	Bacteriophage T4-like capsid assembly protein (Gp20)	-	GO:0005575,GO:0019012	-	-	-	-	-	-	-	-	-	-	-
k59_312230_1	159087.Daro_1191	2.43e-24	97.1	COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,2VTGX@28216|Betaproteobacteria,2KW8E@206389|Rhodocyclales	206389|Rhodocyclales	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k59_1174345_1	565045.NOR51B_1530	2.74e-94	286.0	COG0620@1|root,COG0620@2|Bacteria,1QJ82@1224|Proteobacteria,1TH64@1236|Gammaproteobacteria,1J9IH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	E COG0620 Methionine synthase II (cobalamin-independent)	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
k59_312265_1	1046627.BZARG_1530	6.54e-21	97.1	COG2202@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,4NFC3@976|Bacteroidetes,1HWUK@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_3,PAS_4,PAS_9
k59_819718_1	1206741.BAFX01000095_gene4598	8.1e-14	70.5	COG1047@1|root,COG1047@2|Bacteria,2HJI8@201174|Actinobacteria,4G6V7@85025|Nocardiaceae	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
k59_663517_1	439235.Dalk_1463	1.3e-101	304.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1RJT0@1224|Proteobacteria,43CRQ@68525|delta/epsilon subdivisions,2X7ZB@28221|Deltaproteobacteria,2MPB2@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_1057526_1	767434.Fraau_2882	4.16e-26	101.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,1X86G@135614|Xanthomonadales	135614|Xanthomonadales	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
k59_1057526_2	243365.CV_3741	3.39e-05	47.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,2KQ9Z@206351|Neisseriales	206351|Neisseriales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
k59_742881_1	335543.Sfum_1328	2.5e-87	269.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria,43A0M@68525|delta/epsilon subdivisions,2X9UN@28221|Deltaproteobacteria,2MS7U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
k59_782076_1	1163617.SCD_n02990	1.26e-06	53.1	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,2VIZD@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c
k59_37130_1	9597.XP_003821130.1	4.36e-120	344.0	KOG3317@1|root,KOG3317@2759|Eukaryota,38HIF@33154|Opisthokonta,3BCMD@33208|Metazoa,3CU8J@33213|Bilateria,47YUR@7711|Chordata,48WFT@7742|Vertebrata,3J33U@40674|Mammalia,35DSS@314146|Euarchontoglires,4MC1H@9443|Primates,4N3T1@9604|Hominidae	33208|Metazoa	U	Translocon-associated protein beta (TRAPB)	SSR2	GO:0003674,GO:0005048,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005786,GO:0005789,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031984,GO:0032991,GO:0033036,GO:0033218,GO:0034613,GO:0042175,GO:0042277,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0098827,GO:1990904	-	ko:K13250	ko04141,map04141	M00402	-	-	ko00000,ko00001,ko00002	-	-	-	TRAP_beta
k59_860108_1	443143.GM18_4037	3.66e-68	232.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,42T0V@68525|delta/epsilon subdivisions,2WPRT@28221|Deltaproteobacteria,43TPS@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_1174389_1	521003.COLINT_03280	9.03e-53	184.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CUHN@84998|Coriobacteriia	84998|Coriobacteriia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_703852_1	991905.SL003B_0781	1.68e-60	198.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TTJV@28211|Alphaproteobacteria,4BP8F@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	gyaR2	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_626098_1	1297570.MESS4_120089	8.47e-23	90.9	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,43KHX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_626098_2	1461693.ATO10_01930	3e-21	89.0	COG0454@1|root,COG0454@2|Bacteria,1RDGT@1224|Proteobacteria,2TRF5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
k59_273505_1	314287.GB2207_00645	6.31e-43	161.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_75729_1	644282.Deba_2842	4.37e-78	253.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42M9D@68525|delta/epsilon subdivisions,2WJ43@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_193201_1	404589.Anae109_3037	7.11e-24	103.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,42M3J@68525|delta/epsilon subdivisions,2WJZA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
k59_508002_1	335543.Sfum_1361	1.81e-100	309.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,2MQ6G@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
k59_1134688_1	1121918.ARWE01000001_gene3172	1.34e-74	241.0	COG0025@1|root,COG0025@2|Bacteria,1QTUE@1224|Proteobacteria,43BRM@68525|delta/epsilon subdivisions,2WM4A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,TrkA_N
k59_586567_1	1239962.C943_02828	1.34e-79	258.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
k59_1134689_1	794903.OPIT5_15125	1.04e-06	50.4	COG0745@1|root,COG0745@2|Bacteria,46VWY@74201|Verrucomicrobia,3K7WH@414999|Opitutae	414999|Opitutae	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
k59_1134689_2	1121087.AUCK01000010_gene3106	1.08e-24	106.0	COG5000@1|root,COG5000@2|Bacteria,1VS6X@1239|Firmicutes,4HV7W@91061|Bacilli,1ZS6R@1386|Bacillus	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
k59_1174439_1	1415754.JQMK01000002_gene3377	5.21e-75	248.0	COG0745@1|root,COG2909@1|root,COG0745@2|Bacteria,COG2909@2|Bacteria,1N5KV@1224|Proteobacteria,1SMMI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Trans_reg_C
k59_979410_1	1026882.MAMP_00065	5.15e-61	190.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,460PC@72273|Thiotrichales	72273|Thiotrichales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
k59_742971_1	472759.Nhal_3769	3.36e-88	280.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1WWI3@135613|Chromatiales	135613|Chromatiales	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_369637_1	395493.BegalDRAFT_2575	2.18e-51	176.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,1RP5V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	With LivFGHM is involved in the high affinity leucine transport	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_486805_1	1265505.ATUG01000002_gene1007	2.03e-42	148.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2WKU0@28221|Deltaproteobacteria,2MJ58@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_173204_1	1216007.AOPM01000074_gene1297	2.31e-15	80.9	COG2133@1|root,COG2335@1|root,COG2931@1|root,COG2133@2|Bacteria,COG2335@2|Bacteria,COG2931@2|Bacteria,1R269@1224|Proteobacteria,1S1GT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
k59_643197_1	1432056.X781_15090	7.83e-12	70.1	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1Y8IT@135625|Pasteurellales	135625|Pasteurellales	T	MucB/RseB C-terminal domain	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
k59_329871_1	1183438.GKIL_4246	4.11e-30	120.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1G23H@1117|Cyanobacteria	1117|Cyanobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2,5.3.1.9	ko:K00616,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	PGI,TAL_FSA
k59_291263_1	883080.HMPREF9697_00152	3.27e-18	84.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2TRMH@28211|Alphaproteobacteria,3JRIF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Histidine-specific methyltransferase, SAM-dependent	MA20_09135	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
k59_291263_2	756272.Plabr_3587	1.69e-32	124.0	COG1262@1|root,COG1262@2|Bacteria,2IXRC@203682|Planctomycetes	203682|Planctomycetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
k59_643208_1	525146.Ddes_0546	8.2e-28	109.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42PM0@68525|delta/epsilon subdivisions,2WJRP@28221|Deltaproteobacteria,2M7U4@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM ATPase, BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
k59_643208_2	177437.HRM2_43030	1.06e-06	49.7	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria,2MJN6@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
k59_486828_1	745014.OMB55_00019630	1.55e-46	162.0	COG2374@1|root,COG2374@2|Bacteria,1N5TK@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_643219_1	56780.SYN_03249	1.38e-60	199.0	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,42TEG@68525|delta/epsilon subdivisions,2WPXW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Helix-turn-helix domain of transposase family ISL3	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
k59_1038805_1	1265507.KB899636_gene2357	2.37e-20	89.4	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1Y3FI@135624|Aeromonadales	135624|Aeromonadales	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_1038805_2	156889.Mmc1_1405	2.22e-28	112.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_212610_1	876044.IMCC3088_1278	1.54e-11	65.5	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,1RNMP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008194,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	iSFV_1184.SFV_3438	Glyco_transf_5,Glycos_transf_1
k59_212610_2	323848.Nmul_A0718	5.01e-58	193.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,372V3@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
k59_682741_1	132908.ENSPVAP00000002610	1.32e-137	390.0	COG0081@1|root,KOG1570@2759|Eukaryota,38FV6@33154|Opisthokonta,3BBPG@33208|Metazoa,3CVNG@33213|Bilateria,482MK@7711|Chordata,48W3Y@7742|Vertebrata,3J9NB@40674|Mammalia,4M2CC@9397|Chiroptera	33208|Metazoa	J	Belongs to the universal ribosomal protein uL1 family	RPL10A	GO:0000184,GO:0000470,GO:0000956,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009636,GO:0009892,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015934,GO:0016070,GO:0016071,GO:0016072,GO:0019222,GO:0019439,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0033036,GO:0033365,GO:0034470,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0042221,GO:0042254,GO:0042273,GO:0042493,GO:0042788,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0045471,GO:0046483,GO:0046677,GO:0046700,GO:0046907,GO:0048519,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060255,GO:0065007,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:0097305,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901700,GO:1990904	-	ko:K02865,ko:K04532	ko03010,ko05010,map03010,map05010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04121	-	-	-	Ribosomal_L1
k59_173269_1	1144275.COCOR_05413	2.88e-77	248.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria	1224|Proteobacteria	U	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
k59_1192231_1	1033802.SSPSH_000418	3.27e-76	243.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	glnG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_1113754_1	1173022.Cri9333_3498	6.43e-102	305.0	COG0451@1|root,COG0451@2|Bacteria,1G0GJ@1117|Cyanobacteria,1H9Q3@1150|Oscillatoriales	1117|Cyanobacteria	M	NAD dependent epimerase dehydratase family	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
k59_369713_1	305700.B447_20091	1.15e-12	70.5	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	DUF3318,Peptidase_M48
k59_486881_1	1049564.TevJSym_ca00050	1.04e-68	232.0	COG1033@1|root,COG2834@1|root,COG1033@2|Bacteria,COG2834@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1J96Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	MMPL family	VP1286	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_1152751_2	876044.IMCC3088_2027	2.01e-31	122.0	COG0477@1|root,COG2814@2|Bacteria,1MWKH@1224|Proteobacteria,1RNW6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	yjhB	GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
k59_760790_1	472759.Nhal_2573	1.95e-60	204.0	COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,1WZYU@135613|Chromatiales	135613|Chromatiales	S	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16
k59_1152757_1	207559.Dde_2122	5.3e-15	80.5	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,2M953@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1238	Peptidase_M48,TPR_14,TPR_16,TPR_19
k59_643273_1	1232437.KL662042_gene2012	6.59e-51	175.0	COG2801@1|root,COG2801@2|Bacteria,1R6TH@1224|Proteobacteria,42VCD@68525|delta/epsilon subdivisions,2WRUC@28221|Deltaproteobacteria,2MMEZ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
k59_98898_1	543913.D521_0580	3.11e-79	250.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VHJB@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM D-galactarate dehydratase Altronate hydrolase domain protein	-	-	4.2.1.7,4.4.1.24	ko:K01685,ko:K16846	ko00040,ko00270,ko01100,map00040,map00270,map01100	M00631	R01540,R07633	RC00543,RC01785	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
k59_98898_2	1380367.JIBC01000005_gene2989	3.54e-47	160.0	COG0500@1|root,COG2226@2|Bacteria,1RHJG@1224|Proteobacteria,2U9N0@28211|Alphaproteobacteria,3ZZHG@60136|Sulfitobacter	28211|Alphaproteobacteria	Q	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
k59_1076792_1	290317.Cpha266_1218	1.1e-81	254.0	COG3328@1|root,COG3328@2|Bacteria,1FFEE@1090|Chlorobi	1090|Chlorobi	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
k59_332893_1	933262.AXAM01000020_gene23	5.1e-52	181.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MHS8@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_1155697_2	640132.Srot_0188	1.04e-25	99.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
k59_489884_1	118166.JH976537_gene4798	4.98e-12	69.7	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,1G041@1117|Cyanobacteria,1H9N4@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA_3,PAS_4,PAS_9
k59_19247_1	96561.Dole_1667	2.04e-98	300.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,2MIN7@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
k59_607908_1	1500257.JQNM01000008_gene1271	9.27e-51	176.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,2TUW4@28211|Alphaproteobacteria,4BD00@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function DUF111	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
k59_98916_1	644282.Deba_0626	1.59e-46	163.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,42NUH@68525|delta/epsilon subdivisions,2WISE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal	-	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
k59_802323_1	706587.Desti_1650	7.12e-33	122.0	COG1309@1|root,COG1309@2|Bacteria,1RFVK@1224|Proteobacteria,42RPX@68525|delta/epsilon subdivisions,2WNDJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_450489_1	644282.Deba_2974	1.39e-96	292.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,42S8U@68525|delta/epsilon subdivisions,2WND3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_1237745_1	1123373.ATXI01000032_gene1526	2.8e-88	278.0	COG0369@1|root,COG1151@2|Bacteria,2GHI8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Prismane/CO dehydrogenase family	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_58172_1	9606.ENSP00000365402	4.94e-114	335.0	2CV1G@1|root,2RQEK@2759|Eukaryota,39XY0@33154|Opisthokonta,3BNS8@33208|Metazoa,3D1TZ@33213|Bilateria,483A8@7711|Chordata,48V6P@7742|Vertebrata,3JD16@40674|Mammalia,35BEG@314146|Euarchontoglires,4MQ0X@9443|Primates,4N8BW@9604|Hominidae	33208|Metazoa	U	MHC_I C-terminus	HLA-C	GO:0000139,GO:0001775,GO:0001817,GO:0001819,GO:0001910,GO:0001911,GO:0001912,GO:0001914,GO:0001916,GO:0002250,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002428,GO:0002443,GO:0002444,GO:0002446,GO:0002474,GO:0002475,GO:0002476,GO:0002478,GO:0002479,GO:0002480,GO:0002483,GO:0002484,GO:0002486,GO:0002637,GO:0002639,GO:0002643,GO:0002645,GO:0002664,GO:0002666,GO:0002667,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002695,GO:0002696,GO:0002697,GO:0002698,GO:0002699,GO:0002700,GO:0002702,GO:0002703,GO:0002704,GO:0002705,GO:0002706,GO:0002707,GO:0002708,GO:0002709,GO:0002711,GO:0002715,GO:0002716,GO:0002717,GO:0002718,GO:0002720,GO:0002724,GO:0002726,GO:0002764,GO:0002765,GO:0002767,GO:0002768,GO:0002791,GO:0002793,GO:0002819,GO:0002821,GO:0002822,GO:0002824,GO:0002911,GO:0003674,GO:0003823,GO:0004888,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005783,GO:0005789,GO:0005794,GO:0005795,GO:0005797,GO:0005798,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006968,GO:0007154,GO:0007162,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0008284,GO:0008285,GO:0009595,GO:0009605,GO:0009607,GO:0009617,GO:0009986,GO:0009987,GO:0010008,GO:0010033,GO:0012505,GO:0012506,GO:0012507,GO:0016020,GO:0016021,GO:0016032,GO:0016043,GO:0016045,GO:0016192,GO:0016567,GO:0019221,GO:0019538,GO:0019730,GO:0019731,GO:0019882,GO:0019883,GO:0019884,GO:0019885,GO:0022407,GO:0022408,GO:0022409,GO:0022607,GO:0023052,GO:0030133,GO:0030134,GO:0030135,GO:0030139,GO:0030141,GO:0030155,GO:0030176,GO:0030658,GO:0030659,GO:0030660,GO:0030662,GO:0030666,GO:0030667,GO:0030670,GO:0030881,GO:0031090,GO:0031224,GO:0031226,GO:0031227,GO:0031341,GO:0031342,GO:0031343,GO:0031347,GO:0031348,GO:0031349,GO:0031410,GO:0031901,GO:0031982,GO:0031984,GO:0031985,GO:0032393,GO:0032398,GO:0032446,GO:0032649,GO:0032655,GO:0032656,GO:0032673,GO:0032675,GO:0032679,GO:0032680,GO:0032729,GO:0032735,GO:0032736,GO:0032753,GO:0032759,GO:0032760,GO:0032879,GO:0032880,GO:0032940,GO:0032944,GO:0032945,GO:0032946,GO:0032991,GO:0033218,GO:0034097,GO:0034340,GO:0034341,GO:0036037,GO:0036211,GO:0036230,GO:0038023,GO:0042102,GO:0042110,GO:0042119,GO:0042127,GO:0042129,GO:0042130,GO:0042175,GO:0042221,GO:0042269,GO:0042270,GO:0042277,GO:0042287,GO:0042288,GO:0042590,GO:0042605,GO:0042608,GO:0042611,GO:0042612,GO:0042742,GO:0042802,GO:0042803,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043299,GO:0043312,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045087,GO:0045088,GO:0045089,GO:0045321,GO:0045335,GO:0045580,GO:0045582,GO:0045589,GO:0045591,GO:0045595,GO:0045596,GO:0045597,GO:0045619,GO:0045621,GO:0045785,GO:0045824,GO:0045953,GO:0046631,GO:0046634,GO:0046635,GO:0046640,GO:0046641,GO:0046649,GO:0046703,GO:0046903,GO:0046977,GO:0046978,GO:0046979,GO:0046983,GO:0048002,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050670,GO:0050671,GO:0050672,GO:0050690,GO:0050708,GO:0050714,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050830,GO:0050863,GO:0050865,GO:0050866,GO:0050867,GO:0050868,GO:0050870,GO:0050896,GO:0051023,GO:0051024,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051087,GO:0051093,GO:0051094,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051249,GO:0051250,GO:0051251,GO:0051259,GO:0051262,GO:0051290,GO:0051291,GO:0051606,GO:0051704,GO:0051707,GO:0051716,GO:0055037,GO:0055038,GO:0060089,GO:0060333,GO:0060337,GO:0065003,GO:0065007,GO:0070201,GO:0070647,GO:0070663,GO:0070664,GO:0070665,GO:0070887,GO:0070971,GO:0071310,GO:0071345,GO:0071346,GO:0071357,GO:0071556,GO:0071704,GO:0071840,GO:0071944,GO:0080134,GO:0090087,GO:0097708,GO:0098542,GO:0098543,GO:0098552,GO:0098553,GO:0098581,GO:0098588,GO:0098791,GO:0098796,GO:0098797,GO:0098805,GO:0098827,GO:0099503,GO:1901564,GO:1902105,GO:1902106,GO:1902107,GO:1903037,GO:1903038,GO:1903039,GO:1903530,GO:1903532,GO:1903555,GO:1903557,GO:1903706,GO:1903707,GO:1903708,GO:1904951,GO:2000026,GO:2000564,GO:2000566,GO:2000567,GO:2000568,GO:2001185,GO:2001187,GO:2001198,GO:2001199	2.3.2.27	ko:K06751,ko:K12015	ko04144,ko04145,ko04218,ko04514,ko04612,ko04940,ko05165,ko05166,ko05167,ko05168,ko05169,ko05203,ko05320,ko05330,ko05332,ko05416,map04144,map04145,map04218,map04514,map04612,map04940,map05165,map05166,map05167,map05168,map05169,map05203,map05320,map05330,map05332,map05416	-	-	-	ko00000,ko00001,ko00537,ko01000,ko04121,ko04147,ko04516	-	-	-	C1-set,MHC_I,MHC_I_C
k59_415049_1	639030.JHVA01000001_gene2186	2.44e-18	84.7	COG1048@1|root,COG1048@2|Bacteria,3Y34Q@57723|Acidobacteria,2JHMV@204432|Acidobacteriia	204432|Acidobacteriia	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
k59_415049_2	1094508.Tsac_2473	2.83e-13	71.2	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,42F6N@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_58181_1	883126.HMPREF9710_01109	3.13e-36	142.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria	1224|Proteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_1237786_1	1123360.thalar_03016	6.91e-129	372.0	COG4927@1|root,COG4927@2|Bacteria,1MY0W@1224|Proteobacteria,2TTM1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	choloylglycine hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
k59_332961_1	713586.KB900536_gene1690	2.94e-55	195.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_489939_1	1121403.AUCV01000002_gene563	1.36e-112	352.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,42MVK@68525|delta/epsilon subdivisions,2WKEN@28221|Deltaproteobacteria,2MIWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_920026_2	1247649.D560_0745	4.71e-21	90.9	COG0637@1|root,COG0637@2|Bacteria,1NSPA@1224|Proteobacteria,2WF2A@28216|Betaproteobacteria,3T8TM@506|Alcaligenaceae	28216|Betaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
k59_1195331_1	1131553.JIBI01000055_gene187	7.85e-87	264.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,2VX5Z@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
k59_646163_1	1121405.dsmv_1588	1.5e-44	147.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,2MJT3@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
k59_646163_2	933262.AXAM01000019_gene1098	2.13e-53	171.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,2MJGN@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM CMP dCMP deaminase zinc-binding	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
k59_1003456_1	323261.Noc_0044	2.95e-25	109.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1WX02@135613|Chromatiales	135613|Chromatiales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_415095_1	566466.NOR53_2266	5.46e-80	249.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1J4WY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_98988_1	335543.Sfum_0700	1.97e-89	269.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WNCJ@28221|Deltaproteobacteria,2MQJC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
k59_58221_1	314278.NB231_12264	2.86e-35	133.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,1WX1C@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_294556_1	439235.Dalk_0268	1.66e-80	256.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_529796_1	96561.Dole_0426	2.19e-63	212.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,2MHU3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,sCache_3_2
k59_920078_1	1121403.AUCV01000042_gene141	9.54e-35	136.0	COG3204@1|root,COG3419@1|root,COG3204@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions,2WJYB@28221|Deltaproteobacteria,2MPX7@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_1237851_1	716928.AJQT01000202_gene1884	5.7e-59	184.0	COG3335@1|root,COG3335@2|Bacteria,1RB1C@1224|Proteobacteria,2U367@28211|Alphaproteobacteria,4BC4T@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	protein y4pE y4sA	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_608016_1	1121434.AULY01000014_gene2699	6.13e-31	125.0	COG4412@1|root,COG4932@1|root,COG4412@2|Bacteria,COG4932@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2MEAM@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M36,REJ
k59_920088_1	391612.CY0110_00505	6.1e-33	125.0	COG3367@1|root,COG3367@2|Bacteria,1GBZ5@1117|Cyanobacteria,3KKRZ@43988|Cyanothece	1117|Cyanobacteria	S	COGs COG3367 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_920088_2	1033736.CAHK01000055_gene2866	7.89e-17	83.6	COG0624@1|root,COG0624@2|Bacteria,2GMH2@201174|Actinobacteria,4F9H2@85019|Brevibacteriaceae	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
k59_19373_1	439235.Dalk_4214	4.32e-105	322.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2WJ2N@28221|Deltaproteobacteria,2MI0Z@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_1003544_1	1121405.dsmv_2859	9.53e-52	171.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria,2MJWM@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
k59_1003544_2	96561.Dole_2758	6.29e-19	84.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,2MKHT@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
k59_136873_1	1122194.AUHU01000015_gene3042	1.47e-59	204.0	COG1629@1|root,COG4771@2|Bacteria,1MXSN@1224|Proteobacteria,1RZC0@1236|Gammaproteobacteria,469HA@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_372820_1	933262.AXAM01000109_gene2063	3.48e-85	277.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria,2MI1M@213118|Desulfobacterales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_685980_1	933262.AXAM01000016_gene188	5.42e-64	218.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MIKM@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
k59_1116943_1	1121861.KB899939_gene3779	4.95e-08	59.3	COG0747@1|root,COG0747@2|Bacteria,1MWBH@1224|Proteobacteria,2TTF4@28211|Alphaproteobacteria,2JRC2@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
k59_490031_1	1455608.JDTH01000001_gene3259	1.19e-39	147.0	COG0402@1|root,arCOG00695@2157|Archaea,2XTJS@28890|Euryarchaeota,23TT8@183963|Halobacteria	183963|Halobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_333056_1	1385517.N800_15070	1.49e-62	216.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X41A@135614|Xanthomonadales	135614|Xanthomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1195413_1	1266925.JHVX01000003_gene381	3.7e-75	242.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,372AV@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_1076941_1	187272.Mlg_1311	4.58e-28	109.0	COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,1S2XY@1236|Gammaproteobacteria,1WYES@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_1076941_2	1207076.ALAT01000036_gene4152	6.24e-24	98.2	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,1S9I3@1236|Gammaproteobacteria,1Z2RY@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	COG1525 Micrococcal nuclease (thermonuclease) homologs	Z012_04225	GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Excalibur,SNase
k59_216672_2	96561.Dole_2401	1.39e-21	95.1	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJKZ@28221|Deltaproteobacteria,2MI48@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_450619_1	1123388.AQWU01000064_gene1938	1.13e-08	57.4	COG4177@1|root,COG4177@2|Bacteria,1WJ7X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	branched-chain amino acid transport system, permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_450619_2	585531.HMPREF0063_10398	5.14e-17	83.6	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4DRHN@85009|Propionibacteriales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
k59_802485_1	9606.ENSP00000370125	7.28e-46	152.0	2E0DZ@1|root,2S7UM@2759|Eukaryota,3A599@33154|Opisthokonta,3BRWH@33208|Metazoa,3D8AH@33213|Bilateria,48FHG@7711|Chordata,49C7J@7742|Vertebrata,3JHC9@40674|Mammalia,35QJ2@314146|Euarchontoglires,4MJUD@9443|Primates,4N7GG@9604|Hominidae	33208|Metazoa	K	High mobility group nucleosome binding domain 1	HMGN1	GO:0000720,GO:0000785,GO:0001654,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006290,GO:0006325,GO:0006355,GO:0006357,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007275,GO:0007423,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010224,GO:0010225,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0019219,GO:0019222,GO:0031077,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032784,GO:0032786,GO:0033554,GO:0034641,GO:0040034,GO:0042127,GO:0043010,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048050,GO:0048513,GO:0048518,GO:0048522,GO:0048563,GO:0048569,GO:0048592,GO:0048593,GO:0048597,GO:0048731,GO:0048856,GO:0050678,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051276,GO:0051338,GO:0051347,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090596,GO:0097159,GO:1901360,GO:1901363,GO:1901664,GO:1901666,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K11299	ko05168,map05168	-	-	-	ko00000,ko00001,ko03036	-	-	-	HMG14_17
k59_255296_1	643562.Daes_1255	6.03e-91	287.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2M88M@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
k59_136941_1	1232683.ADIMK_1381	1.57e-45	164.0	COG0834@1|root,COG4191@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RS4V@1236|Gammaproteobacteria,46A0K@72275|Alteromonadaceae	1236|Gammaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SBP_bac_3
k59_1076995_1	1336233.JAEH01000053_gene4112	1.19e-09	63.9	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,2QAD9@267890|Shewanellaceae	1236|Gammaproteobacteria	D	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids	xerC	GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_920176_1	1027273.GZ77_25365	5.33e-64	218.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
k59_842507_1	1410632.JHWW01000002_gene2073	2.38e-05	52.8	COG0463@1|root,COG1887@1|root,COG0463@2|Bacteria,COG1887@2|Bacteria,1TP75@1239|Firmicutes,24ED0@186801|Clostridia,27N95@186928|unclassified Lachnospiraceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
k59_881798_1	1121935.AQXX01000121_gene5585	1.07e-30	117.0	COG1309@1|root,COG1309@2|Bacteria,1MUJ5@1224|Proteobacteria,1RN9W@1236|Gammaproteobacteria,1XPEN@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulator	-	-	-	ko:K22105	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
k59_763952_2	326297.Sama_0084	3.77e-135	403.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,2QA8F@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_608131_1	1333998.M2A_0922	2.06e-54	186.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TQWP@28211|Alphaproteobacteria,4BPPR@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ywrD	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_1116446_2	1280946.HY29_05255	6.59e-45	170.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U3ES@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_724781_1	392499.Swit_4781	2.17e-08	60.8	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U6BM@28211|Alphaproteobacteria,2K23B@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_802000_1	156889.Mmc1_1986	4.68e-05	47.4	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2U1Z0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986,ko:K15342	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	Cas_Cas1,GIIM,RVT_1
k59_607554_1	479433.Caci_6390	0.000707	47.0	COG0726@1|root,COG0726@2|Bacteria,2H6C7@201174|Actinobacteria	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
k59_607562_1	396588.Tgr7_0840	7.29e-41	141.0	COG3193@1|root,COG3193@2|Bacteria,1REF5@1224|Proteobacteria,1T03G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
k59_607562_2	1317124.DW2_03019	1.69e-27	108.0	COG0725@1|root,COG0725@2|Bacteria,1NACV@1224|Proteobacteria,2U20P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
k59_414561_1	501479.ACNW01000062_gene2740	1.18e-103	321.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_881263_1	398578.Daci_4809	5.53e-36	134.0	COG0590@1|root,COG0596@1|root,COG0590@2|Bacteria,COG0596@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,4A9VR@80864|Comamonadaceae	28216|Betaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
k59_881263_2	1307437.J139_14679	1.63e-33	128.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,2Q0PU@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345	SBP_bac_3,SLT
k59_959850_1	1123354.AUDR01000014_gene906	4.62e-34	134.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,1KS9E@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_4
k59_607597_1	159087.Daro_4115	1.27e-31	115.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,2KWEP@206389|Rhodocyclales	206389|Rhodocyclales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
k59_607597_2	1205753.A989_02460	1.59e-20	90.9	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1X2YF@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
k59_1002988_1	1123360.thalar_02729	9.22e-07	54.3	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2TV0E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	fnrL	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
k59_685539_2	887062.HGR_16435	1.29e-33	130.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VHHZ@28216|Betaproteobacteria,4ABUP@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K08351	ko00780,ko01100,map00780,map01100	-	R10127	RC03056	ko00000,ko00001,ko01000,ko02000	5.A.3.4	-	-	Molybdopterin,Molydop_binding
k59_763477_1	1049564.TevJSym_aj00780	1.78e-78	245.0	COG1075@1|root,COG1075@2|Bacteria,1NXDT@1224|Proteobacteria,1SQ0B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
k59_414644_1	1519464.HY22_07645	2.93e-67	231.0	COG2352@1|root,COG2352@2|Bacteria,1FECZ@1090|Chlorobi	1090|Chlorobi	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
k59_959903_1	472759.Nhal_1236	3.03e-56	196.0	COG1033@1|root,COG1033@2|Bacteria,1QW3H@1224|Proteobacteria,1RZA3@1236|Gammaproteobacteria,1X2NT@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_19022_1	10141.ENSCPOP00000015635	7.19e-150	424.0	KOG0118@1|root,KOG0118@2759|Eukaryota,38THR@33154|Opisthokonta,3BCZ7@33208|Metazoa,3CY97@33213|Bilateria,483JQ@7711|Chordata,492KS@7742|Vertebrata,3J2EB@40674|Mammalia,35JEV@314146|Euarchontoglires,4Q2HM@9989|Rodentia	33208|Metazoa	A	eukaryotic translation initiation factor	EIF4H	GO:0000003,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003727,GO:0003729,GO:0003743,GO:0003824,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005844,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019222,GO:0019538,GO:0019953,GO:0022414,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031326,GO:0032268,GO:0032502,GO:0032991,GO:0033592,GO:0034057,GO:0034248,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044877,GO:0048471,GO:0048589,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051704,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097010,GO:0097159,GO:0097617,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_842076_1	1282362.AEAC466_12410	8.93e-16	81.3	COG3660@1|root,COG3660@2|Bacteria,1R70U@1224|Proteobacteria,2TQWV@28211|Alphaproteobacteria,2KF7S@204458|Caulobacterales	204458|Caulobacterales	M	Mitochondrial fission ELM1	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
k59_254874_1	1026882.MAMP_00721	2.21e-29	107.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,4618D@72273|Thiotrichales	72273|Thiotrichales	H	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
k59_254874_2	1395571.TMS3_0119610	1.11e-16	80.5	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_567872_1	1267005.KB911255_gene2506	6.3e-64	216.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,2TR3Z@28211|Alphaproteobacteria,3N6EH@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
k59_136546_1	572477.Alvin_0342	7.32e-19	89.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1WWQS@135613|Chromatiales	135613|Chromatiales	Q	PFAM Mammalian cell entry related	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_136546_2	933262.AXAM01000106_gene2629	1.09e-34	124.0	COG3009@1|root,COG3009@2|Bacteria,1N8BW@1224|Proteobacteria,42UW2@68525|delta/epsilon subdivisions,2WQFD@28221|Deltaproteobacteria,2MNYG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
k59_1237457_1	1121438.JNJA01000016_gene1463	1.2e-20	85.9	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria,42RK0@68525|delta/epsilon subdivisions,2WNZZ@28221|Deltaproteobacteria,2MGM3@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD
k59_1237457_2	335543.Sfum_0822	1.47e-175	500.0	COG1035@1|root,COG1152@1|root,COG1035@2|Bacteria,COG1152@2|Bacteria,1R4GN@1224|Proteobacteria,42P9J@68525|delta/epsilon subdivisions,2WJ9S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.17.1.9	ko:K00125	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_17,FrhB_FdhB_C
k59_1003105_1	177437.HRM2_41870	1.72e-25	101.0	COG2204@1|root,COG2204@2|Bacteria,1RIBG@1224|Proteobacteria,42SAZ@68525|delta/epsilon subdivisions,2WPQ5@28221|Deltaproteobacteria,2MKD6@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
k59_1155502_1	89462.XP_006060735.1	1.34e-147	428.0	KOG2443@1|root,KOG2443@2759|Eukaryota,38G30@33154|Opisthokonta,3BHTS@33208|Metazoa,3CUXM@33213|Bilateria,487MM@7711|Chordata,4957I@7742|Vertebrata,3JCCZ@40674|Mammalia,4JA28@91561|Cetartiodactyla	33208|Metazoa	S	Minor histocompatibility antigen H13 isoform	HM13	GO:0000323,GO:0003674,GO:0003824,GO:0004175,GO:0004190,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005765,GO:0005773,GO:0005774,GO:0005783,GO:0005789,GO:0005791,GO:0005798,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0006810,GO:0006886,GO:0006950,GO:0006986,GO:0008104,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009986,GO:0009987,GO:0010033,GO:0010243,GO:0010467,GO:0010498,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016485,GO:0016787,GO:0019538,GO:0019899,GO:0022607,GO:0030163,GO:0030176,GO:0030660,GO:0030970,GO:0031090,GO:0031224,GO:0031227,GO:0031410,GO:0031625,GO:0031982,GO:0031984,GO:0032527,GO:0032991,GO:0033036,GO:0033554,GO:0033619,GO:0034613,GO:0034620,GO:0034641,GO:0034976,GO:0035966,GO:0035967,GO:0036503,GO:0036513,GO:0042175,GO:0042221,GO:0042500,GO:0042802,GO:0042803,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0046983,GO:0050896,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051603,GO:0051604,GO:0051641,GO:0051649,GO:0051716,GO:0065003,GO:0070001,GO:0070011,GO:0070727,GO:0070887,GO:0071310,GO:0071458,GO:0071556,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0097708,GO:0098552,GO:0098553,GO:0098554,GO:0098562,GO:0098588,GO:0098796,GO:0098805,GO:0098827,GO:0098852,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1903513,GO:1904211	-	ko:K09595	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A22B
k59_1003116_1	1245471.PCA10_10770	7.67e-16	79.3	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1YD4T@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Peptidoglycan polymerase that is essential for cell division	ftsW	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_1003116_2	257313.BP3025	3.64e-11	64.3	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,3T1TK@506|Alcaligenaceae	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_763557_1	1304275.C41B8_11985	2.62e-86	263.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0185,iBWG_1329.BWG_0177,iEC55989_1330.EC55989_0179,iECDH10B_1368.ECDH10B_0165,iECDH1ME8569_1439.ECDH1ME8569_0178,iECED1_1282.ECED1_0191,iECH74115_1262.ECH74115_0195,iECIAI1_1343.ECIAI1_0185,iECNA114_1301.ECNA114_0175,iECO111_1330.ECO111_0186,iECO26_1355.ECO26_0187,iECP_1309.ECP_0193,iECSE_1348.ECSE_0184,iECSF_1327.ECSF_0200,iECSP_1301.ECSP_0184,iECW_1372.ECW_m0181,iECs_1301.ECs0187,iEKO11_1354.EKO11_3733,iEcDH1_1363.EcDH1_3418,iEcE24377_1341.EcE24377A_0189,iEcHS_1320.EcHS_A0187,iG2583_1286.G2583_0188,iJN746.PP_1607,iJO1366.b0185,iJR904.b0185,iLF82_1304.LF82_0008,iNRG857_1313.NRG857_00945,iSDY_1059.SDY_0201,iSFV_1184.SFV_0168,iSF_1195.SF0175,iSFxv_1172.SFxv_0185,iS_1188.S0178,iUMNK88_1353.UMNK88_190,iWFL_1372.ECW_m0181,iY75_1357.Y75_RS00935,iZ_1308.Z0197	ACCA
k59_414741_1	28229.ND2E_1171	4.44e-61	205.0	COG0402@1|root,COG0402@2|Bacteria,1MUFE@1224|Proteobacteria,1RMZR@1236|Gammaproteobacteria,2Q6EY@267889|Colwelliaceae	1236|Gammaproteobacteria	F	Amidohydrolase family	hutF	-	3.5.3.13	ko:K05603	ko00340,map00340	-	R02286	RC00682	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_802165_2	765912.Thimo_2263	2.71e-64	211.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,1RQ6N@1236|Gammaproteobacteria,1WX18@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_1003166_1	190650.CC_2740	1.26e-70	226.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,2KFYE@204458|Caulobacterales	204458|Caulobacterales	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_332742_1	243233.MCA1330	9.75e-36	138.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1XE26@135618|Methylococcales	135618|Methylococcales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19,TPR_6
k59_1195109_1	247156.NFA_31940	7.91e-21	94.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4FW8M@85025|Nocardiaceae	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
k59_763595_1	1121439.dsat_0986	1.42e-74	230.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2WJMH@28221|Deltaproteobacteria,2M84J@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
k59_294300_1	246197.MXAN_5548	8.7e-42	149.0	COG4757@1|root,COG4757@2|Bacteria,1Q1V6@1224|Proteobacteria,435IS@68525|delta/epsilon subdivisions,2WZWF@28221|Deltaproteobacteria,2Z0UC@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
k59_881427_1	871968.DESME_06995	1.71e-29	117.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
k59_685688_1	644282.Deba_1011	3.08e-112	329.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NI5@68525|delta/epsilon subdivisions,2WIN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_1155565_1	1449335.JQLG01000004_gene787	0.000165	45.1	2ENWS@1|root,33GHQ@2|Bacteria,1VQNU@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_294322_1	765911.Thivi_0266	1.97e-38	140.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,1S03J@1236|Gammaproteobacteria,1WYH5@135613|Chromatiales	135613|Chromatiales	S	Major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k59_685701_1	1158165.KB898873_gene590	6.82e-71	236.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1WVYX@135613|Chromatiales	135613|Chromatiales	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_529486_1	1128912.GMES_1315	5.64e-34	127.0	COG0665@1|root,COG0665@2|Bacteria,1Q9VR@1224|Proteobacteria,1S0R4@1236|Gammaproteobacteria,46A05@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
k59_842178_1	523791.Kkor_1405	9.54e-19	85.5	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,1RRK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_842178_2	1122613.ATUP01000001_gene204	2.49e-11	66.6	COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,2U1V8@28211|Alphaproteobacteria,43W9D@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_881468_1	335543.Sfum_2075	2.69e-81	257.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2MQ5R@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
k59_98804_1	998088.B565_3218	5.55e-76	241.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1Y3US@135624|Aeromonadales	135624|Aeromonadales	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_372592_1	984262.SGRA_2631	1.3e-52	188.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,1IR6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_725024_1	226899.F0XSU8	4.73e-15	82.0	COG2272@1|root,KOG4389@2759|Eukaryota,38EC4@33154|Opisthokonta,3Q3UK@4751|Fungi,3RKXH@4890|Ascomycota,21RDI@147550|Sordariomycetes,3UUK1@5151|Ophiostomatales	4751|Fungi	G	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	COesterase
k59_332808_1	566466.NOR53_465	3.26e-72	236.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
k59_372603_1	94122.Shewana3_1188	8.83e-75	237.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria,2Q9BB@267890|Shewanellaceae	1236|Gammaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	yggW	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
k59_646011_1	9606.ENSP00000263574	1.12e-104	323.0	KOG4295@1|root,KOG3540@2759|Eukaryota,38CIE@33154|Opisthokonta,3BBR8@33208|Metazoa,3CUJD@33213|Bilateria,483EW@7711|Chordata,48VZ1@7742|Vertebrata,3J8QG@40674|Mammalia,35AXW@314146|Euarchontoglires,4M8AT@9443|Primates,4MVSP@9604|Hominidae	33208|Metazoa	S	amyloid A4	APLP2	GO:0000003,GO:0000122,GO:0000139,GO:0000185,GO:0000187,GO:0000902,GO:0000904,GO:0001505,GO:0001664,GO:0001774,GO:0001775,GO:0001816,GO:0001878,GO:0001932,GO:0001934,GO:0001967,GO:0002090,GO:0002092,GO:0002119,GO:0002164,GO:0002252,GO:0002263,GO:0002265,GO:0002274,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0002576,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0002694,GO:0002696,GO:0003008,GO:0003674,GO:0003676,GO:0003677,GO:0004857,GO:0004866,GO:0004867,GO:0005102,GO:0005109,GO:0005158,GO:0005178,GO:0005488,GO:0005515,GO:0005539,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005641,GO:0005737,GO:0005768,GO:0005769,GO:0005783,GO:0005788,GO:0005794,GO:0005796,GO:0005802,GO:0005829,GO:0005886,GO:0005887,GO:0005905,GO:0006066,GO:0006139,GO:0006355,GO:0006357,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006464,GO:0006468,GO:0006629,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006873,GO:0006874,GO:0006875,GO:0006878,GO:0006887,GO:0006897,GO:0006915,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0007017,GO:0007018,GO:0007154,GO:0007165,GO:0007166,GO:0007176,GO:0007186,GO:0007187,GO:0007188,GO:0007193,GO:0007204,GO:0007215,GO:0007275,GO:0007346,GO:0007399,GO:0007409,GO:0007411,GO:0007417,GO:0007420,GO:0007422,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007614,GO:0007616,GO:0007617,GO:0007618,GO:0007626,GO:0007631,GO:0007632,GO:0008037,GO:0008038,GO:0008088,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008219,GO:0008277,GO:0008285,GO:0008306,GO:0008344,GO:0008542,GO:0009314,GO:0009416,GO:0009605,GO:0009607,GO:0009611,GO:0009617,GO:0009620,GO:0009628,GO:0009653,GO:0009719,GO:0009791,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010001,GO:0010033,GO:0010171,GO:0010243,GO:0010466,GO:0010467,GO:0010468,GO:0010469,GO:0010511,GO:0010513,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0010720,GO:0010738,GO:0010739,GO:0010799,GO:0010800,GO:0010821,GO:0010823,GO:0010941,GO:0010942,GO:0010950,GO:0010951,GO:0010952,GO:0010970,GO:0012501,GO:0012505,GO:0012506,GO:0014002,GO:0014004,GO:0014005,GO:0014013,GO:0014015,GO:0016020,GO:0016021,GO:0016043,GO:0016049,GO:0016070,GO:0016071,GO:0016125,GO:0016192,GO:0016198,GO:0016199,GO:0016310,GO:0016319,GO:0016322,GO:0016358,GO:0017046,GO:0018996,GO:0019098,GO:0019216,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019722,GO:0019725,GO:0019730,GO:0019731,GO:0019732,GO:0019899,GO:0019904,GO:0019932,GO:0019953,GO:0021700,GO:0021782,GO:0022008,GO:0022404,GO:0022414,GO:0022607,GO:0022898,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030003,GO:0030030,GO:0030097,GO:0030099,GO:0030100,GO:0030111,GO:0030133,GO:0030141,GO:0030154,GO:0030162,GO:0030178,GO:0030182,GO:0030198,GO:0030225,GO:0030234,GO:0030334,GO:0030335,GO:0030414,GO:0030424,GO:0030425,GO:0030534,GO:0030545,GO:0030546,GO:0030548,GO:0030549,GO:0030659,GO:0030667,GO:0030705,GO:0030900,GO:0030901,GO:0031090,GO:0031091,GO:0031092,GO:0031093,GO:0031123,GO:0031124,GO:0031175,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031331,GO:0031344,GO:0031347,GO:0031399,GO:0031401,GO:0031410,GO:0031644,GO:0031646,GO:0031904,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031982,GO:0031983,GO:0031984,GO:0032092,GO:0032101,GO:0032103,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032409,GO:0032412,GO:0032501,GO:0032502,GO:0032504,GO:0032588,GO:0032640,GO:0032872,GO:0032874,GO:0032879,GO:0032880,GO:0032928,GO:0032930,GO:0032940,GO:0032989,GO:0032990,GO:0032991,GO:0032994,GO:0033043,GO:0033130,GO:0033135,GO:0033138,GO:0033218,GO:0033674,GO:0034121,GO:0034185,GO:0034248,GO:0034250,GO:0034358,GO:0034363,GO:0034364,GO:0034385,GO:0034641,GO:0034762,GO:0034765,GO:0034774,GO:0035235,GO:0035556,GO:0036211,GO:0036477,GO:0040007,GO:0040008,GO:0040011,GO:0040012,GO:0040014,GO:0040017,GO:0042056,GO:0042058,GO:0042063,GO:0042116,GO:0042127,GO:0042157,GO:0042176,GO:0042221,GO:0042277,GO:0042303,GO:0042325,GO:0042327,GO:0042330,GO:0042391,GO:0042395,GO:0042551,GO:0042562,GO:0042592,GO:0042742,GO:0042802,GO:0042803,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043030,GO:0043032,GO:0043062,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043197,GO:0043198,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043235,GO:0043269,GO:0043280,GO:0043281,GO:0043393,GO:0043394,GO:0043395,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043549,GO:0043550,GO:0043551,GO:0043552,GO:0043631,GO:0043687,GO:0043933,GO:0044057,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044297,GO:0044309,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044432,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044877,GO:0045055,GO:0045087,GO:0045088,GO:0045121,GO:0045202,GO:0045321,GO:0045428,GO:0045429,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045685,GO:0045687,GO:0045732,GO:0045745,GO:0045787,GO:0045807,GO:0045834,GO:0045859,GO:0045860,GO:0045861,GO:0045862,GO:0045892,GO:0045893,GO:0045931,GO:0045934,GO:0045935,GO:0045937,GO:0045944,GO:0046328,GO:0046330,GO:0046483,GO:0046875,GO:0046889,GO:0046890,GO:0046903,GO:0046907,GO:0046916,GO:0046982,GO:0046983,GO:0048018,GO:0048143,GO:0048167,GO:0048168,GO:0048169,GO:0048259,GO:0048260,GO:0048468,GO:0048469,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048585,GO:0048588,GO:0048589,GO:0048609,GO:0048638,GO:0048666,GO:0048667,GO:0048668,GO:0048669,GO:0048678,GO:0048699,GO:0048708,GO:0048710,GO:0048711,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050730,GO:0050731,GO:0050750,GO:0050767,GO:0050769,GO:0050776,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050803,GO:0050804,GO:0050806,GO:0050807,GO:0050808,GO:0050829,GO:0050830,GO:0050832,GO:0050839,GO:0050865,GO:0050867,GO:0050877,GO:0050885,GO:0050890,GO:0050896,GO:0050905,GO:0050918,GO:0050920,GO:0050921,GO:0051043,GO:0051044,GO:0051049,GO:0051050,GO:0051087,GO:0051090,GO:0051091,GO:0051092,GO:0051094,GO:0051098,GO:0051099,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051270,GO:0051272,GO:0051336,GO:0051338,GO:0051345,GO:0051346,GO:0051347,GO:0051402,GO:0051425,GO:0051480,GO:0051602,GO:0051641,GO:0051649,GO:0051704,GO:0051705,GO:0051707,GO:0051716,GO:0051726,GO:0051896,GO:0051897,GO:0051960,GO:0051962,GO:0052547,GO:0052548,GO:0055065,GO:0055070,GO:0055074,GO:0055076,GO:0055080,GO:0055082,GO:0060205,GO:0060255,GO:0060284,GO:0060322,GO:0060341,GO:0060548,GO:0060560,GO:0060627,GO:0060828,GO:0061097,GO:0061098,GO:0061134,GO:0061135,GO:0061515,GO:0061564,GO:0061844,GO:0061888,GO:0061890,GO:0061900,GO:0061901,GO:0061903,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070206,GO:0070302,GO:0070304,GO:0070325,GO:0070372,GO:0070374,GO:0070381,GO:0070382,GO:0070887,GO:0070997,GO:0071071,GO:0071073,GO:0071310,GO:0071417,GO:0071495,GO:0071675,GO:0071677,GO:0071695,GO:0071704,GO:0071706,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072503,GO:0072507,GO:0080090,GO:0080134,GO:0080135,GO:0090025,GO:0090026,GO:0090087,GO:0090090,GO:0090218,GO:0090304,GO:0090322,GO:0090647,GO:0097159,GO:0097367,GO:0097435,GO:0097447,GO:0097458,GO:0097485,GO:0097644,GO:0097645,GO:0097708,GO:0098542,GO:0098588,GO:0098589,GO:0098657,GO:0098771,GO:0098772,GO:0098791,GO:0098794,GO:0098805,GO:0098815,GO:0098857,GO:0098962,GO:0099111,GO:0099175,GO:0099177,GO:0099503,GO:0099601,GO:0099602,GO:0106003,GO:0106027,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0150003,GO:1900120,GO:1900122,GO:1900180,GO:1900181,GO:1900271,GO:1900272,GO:1900273,GO:1900407,GO:1900409,GO:1900449,GO:1901184,GO:1901214,GO:1901215,GO:1901216,GO:1901222,GO:1901224,GO:1901360,GO:1901363,GO:1901564,GO:1901615,GO:1901652,GO:1901653,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902003,GO:1902004,GO:1902531,GO:1902533,GO:1902652,GO:1902679,GO:1902680,GO:1902882,GO:1902884,GO:1902903,GO:1902905,GO:1902947,GO:1902949,GO:1902950,GO:1902991,GO:1902993,GO:1903048,GO:1903201,GO:1903203,GO:1903209,GO:1903223,GO:1903426,GO:1903428,GO:1903506,GO:1903507,GO:1903508,GO:1903725,GO:1903727,GO:1903827,GO:1903828,GO:1903978,GO:1903980,GO:1904020,GO:1904022,GO:1904062,GO:1904399,GO:1904407,GO:1904589,GO:1904591,GO:1904645,GO:1904646,GO:1904951,GO:1905891,GO:1905893,GO:1905894,GO:1905896,GO:1905897,GO:1905898,GO:1905906,GO:1905908,GO:1905945,GO:1990000,GO:1990535,GO:1990777,GO:2000026,GO:2000112,GO:2000113,GO:2000116,GO:2000145,GO:2000147,GO:2000273,GO:2000310,GO:2000377,GO:2000379,GO:2000401,GO:2000403,GO:2000404,GO:2000406,GO:2000463,GO:2001056,GO:2001141,GO:2001257	-	ko:K04520,ko:K08117	ko04726,ko05010,map04726,map05010	-	-	-	ko00000,ko00001,ko00535,ko00536	-	-	-	APP_Cu_bd,APP_E2,APP_N,APP_amyloid,Kunitz_BPTI
k59_725036_1	403833.Pmob_1143	4.53e-20	94.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.270	ko:K21369	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
k59_763656_1	1122614.JHZF01000013_gene3462	1.33e-43	152.0	COG0385@1|root,COG0385@2|Bacteria	2|Bacteria	S	bile acid:sodium symporter activity	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
k59_529551_1	96561.Dole_0756	1.58e-81	253.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2MHW4@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
k59_372632_1	238854.Q5GQN1_BPSYP	3.66e-36	138.0	4QFP9@10239|Viruses,4QWU0@35237|dsDNA viruses  no RNA stage,4QSRT@28883|Caudovirales,4QJW5@10662|Myoviridae	10662|Myoviridae	-	-	-	GO:0005575,GO:0019012	-	-	-	-	-	-	-	-	-	-	-
k59_529601_1	991905.SL003B_2515	1.31e-73	233.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TS1R@28211|Alphaproteobacteria,4BRRG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_685796_1	644282.Deba_2183	2.24e-84	277.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_568054_1	105559.Nwat_2116	8.38e-31	111.0	COG1993@1|root,COG1993@2|Bacteria,1N0EM@1224|Proteobacteria,1SH3G@1236|Gammaproteobacteria,1X26G@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
k59_568054_2	1232437.KL661988_gene214	3.9e-27	102.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,2MKW0@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
k59_1116770_1	686340.Metal_1349	6.1e-29	113.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,1RR0T@1236|Gammaproteobacteria,1XG8N@135618|Methylococcales	135618|Methylococcales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_19229_1	9606.ENSP00000434515	3.28e-154	444.0	2CMU1@1|root,2QRYG@2759|Eukaryota,38H22@33154|Opisthokonta,3BHKN@33208|Metazoa,3CWTX@33213|Bilateria,47ZXI@7711|Chordata,48ZPM@7742|Vertebrata,3J4AZ@40674|Mammalia,35F8X@314146|Euarchontoglires,4M7HF@9443|Primates,4N3QW@9604|Hominidae	33208|Metazoa	S	Major Facilitator Superfamily	SLC43A3	-	-	ko:K08230	-	-	-	-	ko00000,ko02000	-	-	-	MFS_1
k59_1116775_1	1049564.TevJSym_bn00120	5.78e-57	183.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1JAMF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphoribosyl transferase domain	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
k59_610427_1	236097.ADG881_588	1.13e-52	176.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1XHIV@135619|Oceanospirillales	135619|Oceanospirillales	T	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_375208_1	357804.Ping_0228	1.93e-31	125.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,2QIWG@267894|Psychromonadaceae	1236|Gammaproteobacteria	E	Semialdehyde dehydrogenase, NAD binding domain	argC	GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iSSON_1240.SSON_4131	Semialdhyde_dh,Semialdhyde_dhC
k59_219954_1	926554.KI912647_gene1814	1.67e-19	94.4	COG1529@1|root,COG1529@2|Bacteria,1WKY4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
k59_101595_1	251221.35212378	1.83e-18	89.7	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667,HlyD_3
k59_922454_2	114615.BRADO0919	4e-08	54.3	COG0625@1|root,COG0625@2|Bacteria,1Q9ND@1224|Proteobacteria,2TT22@28211|Alphaproteobacteria,3JX9Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
k59_570634_1	1267005.KB911257_gene955	3.29e-101	325.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2TR7N@28211|Alphaproteobacteria,3N66S@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	helicase superfamily c-terminal domain	mgpS	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C
k59_156828_2	111781.Lepto7376_3541	9.66e-07	53.9	COG3210@1|root,COG3210@2|Bacteria,1G0EK@1117|Cyanobacteria	1117|Cyanobacteria	U	TIGRFAM filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
k59_1057979_1	439235.Dalk_3266	1.48e-119	382.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_1057979_2	589865.DaAHT2_2650	2.8e-15	75.9	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase	bamE	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,NAD_binding_8,Pyr_redox_2
k59_196021_1	257310.BB2814	0.00019	43.1	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,2VKYM@28216|Betaproteobacteria,3T8RR@506|Alcaligenaceae	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_822907_1	1380394.JADL01000012_gene823	9.16e-46	166.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,2TS48@28211|Alphaproteobacteria,2JRFE@204441|Rhodospirillales	204441|Rhodospirillales	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_862154_1	1265313.HRUBRA_01487	5.97e-50	167.0	COG3751@1|root,COG3751@2|Bacteria,1R4BC@1224|Proteobacteria,1T1C3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
k59_470313_1	596151.DesfrDRAFT_2501	7.86e-69	219.0	COG1566@1|root,COG1566@2|Bacteria,1MWG0@1224|Proteobacteria,42NAT@68525|delta/epsilon subdivisions,2WPPB@28221|Deltaproteobacteria,2MBTW@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_705425_1	1385935.N836_12705	3.57e-46	171.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria,1HDU6@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
k59_156874_1	1218074.BAXZ01000006_gene1572	1.25e-26	107.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2W2VR@28216|Betaproteobacteria,1K5JP@119060|Burkholderiaceae	28216|Betaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_1136408_2	246194.CHY_1766	1.82e-43	159.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,42EP2@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k59_1058021_1	511062.GU3_14165	5.43e-26	112.0	COG1638@1|root,COG1638@2|Bacteria,1QWNV@1224|Proteobacteria,1RQXG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG4663 TRAP-type mannitol chloroaromatic compound transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_744599_1	1232437.KL661954_gene2354	2.48e-50	170.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,42M2F@68525|delta/epsilon subdivisions,2WKUG@28221|Deltaproteobacteria,2MM3S@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
k59_197_1	56780.SYN_01040	3.93e-26	109.0	COG1038@1|root,COG1038@2|Bacteria,1R7P1@1224|Proteobacteria,42PQ3@68525|delta/epsilon subdivisions,2WJK5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Conserved carboxylase domain	-	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
k59_783814_1	1262915.BN574_00819	1.57e-06	55.1	COG0477@1|root,COG2814@2|Bacteria,1UY3M@1239|Firmicutes,4H6U2@909932|Negativicutes	909932|Negativicutes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_822970_1	1249627.D779_0542	4.13e-64	213.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1WW0B@135613|Chromatiales	135613|Chromatiales	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_548791_1	331869.BAL199_08718	1.53e-23	104.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2TS41@28211|Alphaproteobacteria,4BPC5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
k59_313680_1	9606.ENSP00000358866	9.53e-205	627.0	COG5069@1|root,KOG0518@2759|Eukaryota,38DME@33154|Opisthokonta,3B9WI@33208|Metazoa,3CS2N@33213|Bilateria,480F7@7711|Chordata,49204@7742|Vertebrata,3JD57@40674|Mammalia,35H1Q@314146|Euarchontoglires,4ME6N@9443|Primates,4N2S4@9604|Hominidae	33208|Metazoa	Z	Filamin-type immunoglobulin domains	FLNA	GO:0000003,GO:0000226,GO:0000278,GO:0000280,GO:0000902,GO:0000904,GO:0001525,GO:0001568,GO:0001664,GO:0001775,GO:0001837,GO:0001944,GO:0001974,GO:0002009,GO:0002011,GO:0002064,GO:0002576,GO:0003006,GO:0003007,GO:0003674,GO:0003779,GO:0005080,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005730,GO:0005737,GO:0005794,GO:0005802,GO:0005829,GO:0005856,GO:0005884,GO:0005886,GO:0005903,GO:0005911,GO:0005938,GO:0006139,GO:0006351,GO:0006355,GO:0006356,GO:0006366,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006935,GO:0006937,GO:0006942,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007016,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007154,GO:0007165,GO:0007166,GO:0007186,GO:0007187,GO:0007188,GO:0007193,GO:0007195,GO:0007212,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007413,GO:0007417,GO:0007420,GO:0007507,GO:0007548,GO:0007596,GO:0007599,GO:0008016,GO:0008037,GO:0008038,GO:0008092,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008284,GO:0008406,GO:0008584,GO:0009058,GO:0009059,GO:0009299,GO:0009605,GO:0009611,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010638,GO:0010646,GO:0010647,GO:0010720,GO:0010721,GO:0010769,GO:0010770,GO:0010810,GO:0010811,GO:0010941,GO:0010959,GO:0010975,GO:0010977,GO:0012505,GO:0015459,GO:0015629,GO:0016020,GO:0016021,GO:0016043,GO:0016070,GO:0016071,GO:0016192,GO:0016247,GO:0016477,GO:0016479,GO:0016482,GO:0017016,GO:0017048,GO:0017160,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019900,GO:0019901,GO:0021535,GO:0021932,GO:0021943,GO:0022008,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030030,GO:0030031,GO:0030036,GO:0030054,GO:0030154,GO:0030155,GO:0030168,GO:0030182,GO:0030334,GO:0030335,GO:0030424,GO:0030425,GO:0030426,GO:0030427,GO:0030506,GO:0030855,GO:0030863,GO:0030902,GO:0031175,GO:0031224,GO:0031267,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031344,GO:0031345,GO:0031523,GO:0031532,GO:0031628,GO:0031647,GO:0031674,GO:0031852,GO:0031974,GO:0031981,GO:0031984,GO:0032231,GO:0032233,GO:0032432,GO:0032501,GO:0032502,GO:0032507,GO:0032774,GO:0032879,GO:0032940,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033267,GO:0034329,GO:0034330,GO:0034394,GO:0034613,GO:0034641,GO:0034645,GO:0034654,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0034987,GO:0034988,GO:0035239,GO:0035295,GO:0036477,GO:0040011,GO:0040012,GO:0040017,GO:0042060,GO:0042127,GO:0042176,GO:0042177,GO:0042221,GO:0042330,GO:0042383,GO:0042391,GO:0042789,GO:0042802,GO:0042803,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043034,GO:0043066,GO:0043067,GO:0043069,GO:0043113,GO:0043122,GO:0043123,GO:0043170,GO:0043198,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043266,GO:0043268,GO:0043269,GO:0043270,GO:0043292,GO:0043433,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044297,GO:0044319,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044427,GO:0044428,GO:0044430,GO:0044431,GO:0044444,GO:0044446,GO:0044448,GO:0044449,GO:0044463,GO:0044464,GO:0044782,GO:0044877,GO:0045022,GO:0045055,GO:0045137,GO:0045184,GO:0045185,GO:0045216,GO:0045595,GO:0045596,GO:0045597,GO:0045664,GO:0045665,GO:0045785,GO:0045892,GO:0045934,GO:0046332,GO:0046483,GO:0046546,GO:0046661,GO:0046903,GO:0046907,GO:0046983,GO:0048285,GO:0048365,GO:0048468,GO:0048471,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048608,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048729,GO:0048731,GO:0048762,GO:0048771,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050767,GO:0050768,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050817,GO:0050821,GO:0050878,GO:0050896,GO:0051015,GO:0051020,GO:0051049,GO:0051050,GO:0051090,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051179,GO:0051220,GO:0051225,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051270,GO:0051272,GO:0051493,GO:0051495,GO:0051641,GO:0051649,GO:0051651,GO:0051668,GO:0051674,GO:0051716,GO:0051764,GO:0051960,GO:0051961,GO:0051962,GO:0055117,GO:0060008,GO:0060009,GO:0060065,GO:0060255,GO:0060271,GO:0060284,GO:0060306,GO:0060322,GO:0060372,GO:0060429,GO:0060485,GO:0060548,GO:0061038,GO:0061458,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070727,GO:0070925,GO:0071526,GO:0071704,GO:0071840,GO:0071944,GO:0072358,GO:0072359,GO:0072657,GO:0072659,GO:0080090,GO:0086004,GO:0090257,GO:0090304,GO:0090307,GO:0090504,GO:0090505,GO:0097368,GO:0097435,GO:0097440,GO:0097447,GO:0097458,GO:0097485,GO:0097659,GO:0098772,GO:0098791,GO:0098862,GO:0098900,GO:0098901,GO:0098903,GO:0098910,GO:0098927,GO:0099080,GO:0099081,GO:0099106,GO:0099512,GO:0099513,GO:0099568,GO:0099623,GO:0106030,GO:0110053,GO:0120025,GO:0120031,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0140014,GO:0150034,GO:1900024,GO:1900026,GO:1901360,GO:1901362,GO:1901379,GO:1901381,GO:1901576,GO:1902396,GO:1902414,GO:1902531,GO:1902533,GO:1902679,GO:1902850,GO:1902903,GO:1902905,GO:1903047,GO:1903115,GO:1903506,GO:1903507,GO:1903522,GO:1903779,GO:1904062,GO:1904064,GO:1905000,GO:1905031,GO:1990778,GO:2000026,GO:2000112,GO:2000113,GO:2000145,GO:2000147,GO:2000177,GO:2000179,GO:2001044,GO:2001046,GO:2001141,GO:2001222,GO:2001224	-	ko:K04437	ko04010,ko04510,ko05132,ko05205,map04010,map04510,map05132,map05205	-	-	-	ko00000,ko00001,ko04147,ko04812	-	-	-	CH,Filamin
k59_470395_1	1384049.CD29_09435	4.72e-33	126.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HJ21@91061|Bacilli,3IXKC@400634|Lysinibacillus	91061|Bacilli	S	Cysteine-rich secretory protein family	ykwD	-	-	-	-	-	-	-	-	-	-	-	CAP
k59_862252_2	298386.PBPRA1265	8.37e-72	237.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,1RMHR@1236|Gammaproteobacteria,1XUC7@135623|Vibrionales	135623|Vibrionales	Q	COG2015 Alkyl sulfatase and related hydrolases	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
k59_470396_1	76114.p2A146	5.43e-90	278.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2VK6J@28216|Betaproteobacteria,2KX2N@206389|Rhodocyclales	206389|Rhodocyclales	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_117774_1	439235.Dalk_4875	3.01e-12	68.2	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,42QQX@68525|delta/epsilon subdivisions,2WWFF@28221|Deltaproteobacteria,2MPFI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
k59_548802_1	1269813.ATUL01000017_gene2555	1.02e-14	78.2	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1WWK8@135613|Chromatiales	135613|Chromatiales	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
k59_548814_1	105559.Nwat_0242	6.88e-144	417.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1WWG7@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k59_39377_1	331869.BAL199_16213	3.11e-62	202.0	COG2175@1|root,COG2175@2|Bacteria,1Q0C7@1224|Proteobacteria,2TRGF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA	-	-	-	-	-	-	-	-	-	-	-	-	TauD
k59_783871_1	1493511.A0A0E3HH58_9CAUD	3.45e-91	275.0	4QAR1@10239|Viruses,4QPJE@28883|Caudovirales,4QI9Y@10662|Myoviridae	10662|Myoviridae	S	ATPase family associated with various cellular activities (AAA)	-	GO:0008150,GO:0016032,GO:0019058,GO:0019079,GO:0039686,GO:0039693,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	-
k59_39378_1	1238182.C882_0535	9.96e-127	369.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2TSAD@28211|Alphaproteobacteria,2JQ1D@204441|Rhodospirillales	204441|Rhodospirillales	G	Fructose-bisphosphate aldolase class-II	cbbA	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
k59_823064_1	1121405.dsmv_3645	1.16e-114	362.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MI5C@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_470436_2	631454.N177_3090	2.99e-19	87.4	COG3333@1|root,COG3333@2|Bacteria	2|Bacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
k59_431287_1	1123514.KB905899_gene918	7.45e-36	128.0	COG0664@1|root,COG0664@2|Bacteria,1NPK3@1224|Proteobacteria	1224|Proteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_431287_2	1121935.AQXX01000119_gene4803	1.26e-62	211.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,1RYCE@1236|Gammaproteobacteria,1XMXM@135619|Oceanospirillales	135619|Oceanospirillales	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
k59_336_2	1499967.BAYZ01000013_gene6453	4.39e-31	119.0	2CC7H@1|root,32RJ0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1018963_1	665571.STHERM_c12890	1.5e-84	261.0	COG2873@1|root,COG2873@2|Bacteria,2J5MU@203691|Spirochaetes	203691|Spirochaetes	E	PFAM Cys Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_156984_1	1121413.JMKT01000016_gene52	3.27e-29	105.0	2EBU9@1|root,335TV@2|Bacteria,1NEIU@1224|Proteobacteria,42V7Y@68525|delta/epsilon subdivisions,2WRJ1@28221|Deltaproteobacteria,2MDRW@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_156984_2	1121405.dsmv_0263	4.27e-48	167.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2MNJX@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
k59_1018989_1	479434.Sthe_1742	7.21e-89	295.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi,27YSS@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_744768_1	1121878.AUGL01000021_gene2815	5.33e-93	290.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_548885_1	933262.AXAM01000066_gene1683	2.33e-75	232.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2WJM8@28221|Deltaproteobacteria,2MI5W@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_1019018_1	565045.NOR51B_1830	7.02e-66	211.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1J54C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECS88_1305.ECS88_0100	LpxC
k59_548887_1	1397527.Q670_05755	4.87e-100	309.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1XNMY@135619|Oceanospirillales	135619|Oceanospirillales	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_117864_1	349124.Hhal_0865	1.56e-91	298.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_705628_1	388051.AUFE01000099_gene3773	2.44e-116	339.0	COG3384@1|root,COG3384@2|Bacteria,1MWNC@1224|Proteobacteria,2VVDD@28216|Betaproteobacteria,1KH1E@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	LigB
k59_509658_1	525368.HMPREF0591_5392	6.5e-41	147.0	COG0688@1|root,COG0688@2|Bacteria,2IBDY@201174|Actinobacteria,236VW@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the phosphatidylserine decarboxylase family	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PSDC,PS_Dcarbxylase
k59_463_1	439235.Dalk_0950	1.69e-26	98.6	COG3360@1|root,COG3360@2|Bacteria,1Q2I5@1224|Proteobacteria,42VRR@68525|delta/epsilon subdivisions,2WRD2@28221|Deltaproteobacteria,2MM5C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
k59_463_2	880072.Desac_0487	7.36e-50	162.0	2DWSR@1|root,341Q6@2|Bacteria,1Q538@1224|Proteobacteria,430G3@68525|delta/epsilon subdivisions,2WVK2@28221|Deltaproteobacteria,2MRYW@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_589388_3	1392487.JIAD01000001_gene593	2.49e-23	105.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,25UTF@186806|Eubacteriaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
k59_667698_1	156889.Mmc1_2685	2.44e-07	55.8	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
k59_1098699_1	1005995.GTPT_2346	4.23e-44	154.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,4BUV2@82986|Tatumella	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfD	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_1137856_1	1499967.BAYZ01000048_gene2713	1.04e-51	180.0	COG2103@1|root,COG2103@2|Bacteria,2NP6Y@2323|unclassified Bacteria	2|Bacteria	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
k59_393412_1	1123366.TH3_02775	1.04e-38	141.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,2TVBG@28211|Alphaproteobacteria,2JSA7@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_40660_1	1121448.DGI_2225	8.18e-41	156.0	COG0577@1|root,COG2234@1|root,COG0577@2|Bacteria,COG2234@2|Bacteria,1MVYE@1224|Proteobacteria,42PKN@68525|delta/epsilon subdivisions,2WIWP@28221|Deltaproteobacteria,2M8ZJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,PA,Peptidase_M28
k59_119202_1	387093.SUN_0903	6.74e-43	157.0	COG2985@1|root,COG3273@1|root,COG2985@2|Bacteria,COG3273@2|Bacteria,1MUVM@1224|Proteobacteria,42P36@68525|delta/epsilon subdivisions,2YPIH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	YidE YbjL	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
k59_119203_2	63737.Npun_F3457	2.38e-09	61.2	COG0457@1|root,COG4122@1|root,COG0457@2|Bacteria,COG4122@2|Bacteria,1G5B0@1117|Cyanobacteria,1HRTI@1161|Nostocales	1117|Cyanobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,TPR_2
k59_79937_1	1232437.KL662036_gene2711	6.93e-64	218.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2WKWS@28221|Deltaproteobacteria,2MKJJ@213118|Desulfobacterales	28221|Deltaproteobacteria	GT	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
k59_197537_1	3067.XP_002951684.1	1.32e-26	109.0	KOG1610@1|root,KOG1610@2759|Eukaryota,388MC@33090|Viridiplantae,34P25@3041|Chlorophyta	3041|Chlorophyta	Q	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_589428_1	394.NGR_c08340	4.18e-86	266.0	COG3547@1|root,COG3547@2|Bacteria,1QYJU@1224|Proteobacteria,2U1TU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_902749_1	69042.WH5701_04825	4.84e-07	51.2	COG0561@1|root,COG0561@2|Bacteria,1G5N9@1117|Cyanobacteria,1H2K4@1129|Synechococcus	1117|Cyanobacteria	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	S6PP
k59_902749_2	1265505.ATUG01000002_gene2289	1.93e-38	138.0	COG0524@1|root,COG0524@2|Bacteria,1Q1GY@1224|Proteobacteria,42REZ@68525|delta/epsilon subdivisions,2WNHE@28221|Deltaproteobacteria,2MJYD@213118|Desulfobacterales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_902756_1	694430.Natoc_0740	1.34e-20	91.7	COG0365@1|root,arCOG04201@2157|Archaea,2XSTQ@28890|Euryarchaeota,23TRN@183963|Halobacteria	183963|Halobacteria	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
k59_1862_1	1127673.GLIP_3822	2.21e-91	274.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,4686H@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_1216257_1	990285.RGCCGE502_16365	7.28e-61	199.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria,4BA0J@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k59_785249_1	686340.Metal_1796	9.29e-62	200.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,1XDS5@135618|Methylococcales	135618|Methylococcales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
k59_785249_2	936573.HMPREF1147_0772	1.6e-08	55.1	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,4H2HM@909932|Negativicutes	909932|Negativicutes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_393472_1	1123373.ATXI01000014_gene24	8.04e-30	116.0	COG0374@1|root,COG0374@2|Bacteria,2GH4N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_393472_2	439235.Dalk_2276	1.18e-100	307.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria,2MI12@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hynA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.12.2.1,1.12.5.1,1.12.7.2,1.12.99.6	ko:K00437,ko:K00533,ko:K05922,ko:K06281	ko00633,ko01120,map00633,map01120	-	R00019,R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
k59_236709_1	56780.SYN_01263	3.46e-109	326.0	COG1127@1|root,COG2199@1|root,COG1127@2|Bacteria,COG2199@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MQX9@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
k59_79990_1	1423743.JCM14108_3078	9.52e-29	114.0	COG1028@1|root,COG1028@2|Bacteria,1TRQC@1239|Firmicutes,4HD7P@91061|Bacilli,3F4FH@33958|Lactobacillaceae	91061|Bacilli	IQ	reductase	butA	-	1.1.1.304,1.1.1.76	ko:K03366	ko00650,map00650	-	R02855,R02946,R03707,R09078,R10505	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
k59_1020357_1	236097.ADG881_3011	7.93e-125	368.0	COG3457@1|root,COG3457@2|Bacteria,1MW9K@1224|Proteobacteria,1S1TM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
k59_981241_1	7994.ENSAMXP00000014076	7.79e-44	167.0	COG5022@1|root,KOG0161@2759|Eukaryota,38CVC@33154|Opisthokonta,3BBPR@33208|Metazoa,3CSM1@33213|Bilateria,480QG@7711|Chordata,490K5@7742|Vertebrata,49WAH@7898|Actinopterygii	33208|Metazoa	Z	Myosin, heavy chain	MYH1	GO:0000146,GO:0000166,GO:0003008,GO:0003009,GO:0003012,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003774,GO:0003779,GO:0003824,GO:0004721,GO:0004722,GO:0005198,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005911,GO:0006139,GO:0006163,GO:0006464,GO:0006470,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006936,GO:0006941,GO:0008092,GO:0008144,GO:0008150,GO:0008152,GO:0008307,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009605,GO:0009612,GO:0009628,GO:0009629,GO:0009987,GO:0014704,GO:0014823,GO:0014850,GO:0015629,GO:0016311,GO:0016459,GO:0016460,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0016887,GO:0017018,GO:0017022,GO:0017076,GO:0017111,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0030016,GO:0030017,GO:0030029,GO:0030048,GO:0030049,GO:0030054,GO:0030554,GO:0031672,GO:0032027,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032982,GO:0032991,GO:0033275,GO:0034641,GO:0035639,GO:0035770,GO:0035994,GO:0036094,GO:0036211,GO:0036464,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044291,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0046034,GO:0046483,GO:0048856,GO:0050879,GO:0050881,GO:0050896,GO:0051015,GO:0055086,GO:0061061,GO:0070252,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:0099080,GO:0099081,GO:0099512,GO:0140096,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1990904	-	ko:K10352,ko:K17751	ko04260,ko04261,ko04530,ko05416,map04260,map04261,map04530,map05416	-	-	-	ko00000,ko00001,ko04147,ko04812	-	-	-	Myosin_N,Myosin_head,Myosin_tail_1
k59_197577_1	439235.Dalk_1330	1.94e-56	188.0	COG3464@1|root,COG3464@2|Bacteria,1PFY7@1224|Proteobacteria,4377W@68525|delta/epsilon subdivisions,2X29U@28221|Deltaproteobacteria,2MP93@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Helix-turn-helix domain of transposase family ISL3	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3
k59_420811_1	999611.KI421504_gene2533	9.24e-111	325.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TRGY@28211|Alphaproteobacteria,281XJ@191028|Leisingera	28211|Alphaproteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_420811_2	13689.BV96_04745	2.51e-187	535.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria,2K2UN@204457|Sphingomonadales	204457|Sphingomonadales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_885997_1	1121374.KB891575_gene1092	4.49e-10	65.5	COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0823 Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
k59_1242568_2	96561.Dole_1179	1.18e-46	157.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2MJ9P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
k59_535825_1	439235.Dalk_0578	1.27e-40	146.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,42M7Q@68525|delta/epsilon subdivisions,2WJ9Z@28221|Deltaproteobacteria,2MIK8@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_806371_1	349106.PsycPRwf_1623	1.18e-16	76.3	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,3NSJK@468|Moraxellaceae	1236|Gammaproteobacteria	K	Bacterial regulatory protein, Fis family	fis	GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
k59_806371_2	1042377.AFPJ01000032_gene2713	0.000471	42.4	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,4646Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	purH	GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEcHS_1320.EcHS_A4240,iPC815.YPO3728	AICARFT_IMPCHas,MGS
k59_768170_1	1510531.JQJJ01000012_gene1690	3.46e-40	147.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2TTBH@28211|Alphaproteobacteria,3JXA3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
k59_1242589_1	9597.XP_003806351.1	5.95e-125	370.0	COG0111@1|root,KOG0068@2759|Eukaryota,38GJA@33154|Opisthokonta,3BEWZ@33208|Metazoa,3CTJ7@33213|Bilateria,484RB@7711|Chordata,494HT@7742|Vertebrata,3J3US@40674|Mammalia,35GH2@314146|Euarchontoglires,4MBF9@9443|Primates,4N5W9@9604|Hominidae	33208|Metazoa	E	Catalyzes the reversible oxidation of 3-phospho-D- glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate	PHGDH	GO:0001505,GO:0003674,GO:0003824,GO:0004617,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006541,GO:0006544,GO:0006563,GO:0006564,GO:0006566,GO:0006790,GO:0006805,GO:0006807,GO:0007049,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0008652,GO:0009055,GO:0009058,GO:0009064,GO:0009066,GO:0009069,GO:0009070,GO:0009410,GO:0009448,GO:0009790,GO:0009792,GO:0009888,GO:0009987,GO:0010001,GO:0010468,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019222,GO:0019530,GO:0019694,GO:0019752,GO:0021510,GO:0021782,GO:0021915,GO:0022008,GO:0022402,GO:0022900,GO:0030030,GO:0030154,GO:0030182,GO:0031175,GO:0032501,GO:0032502,GO:0032787,GO:0035295,GO:0042063,GO:0042133,GO:0042221,GO:0043009,GO:0043209,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048468,GO:0048513,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050896,GO:0051716,GO:0055114,GO:0060255,GO:0060322,GO:0060429,GO:0065007,GO:0065008,GO:0070314,GO:0070887,GO:0071466,GO:0071704,GO:0071840,GO:0120036,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1008947_1	9606.ENSP00000433999	2.8e-233	647.0	KOG4308@1|root,KOG4308@2759|Eukaryota,39SPJ@33154|Opisthokonta,3BGVK@33208|Metazoa,3CXUK@33213|Bilateria,485F1@7711|Chordata,490KC@7742|Vertebrata,3J3E6@40674|Mammalia,35BT1@314146|Euarchontoglires,4MHED@9443|Primates,4MUIY@9604|Hominidae	33208|Metazoa	S	ribonuclease inhibitor activity	RNH1	GO:0003674,GO:0004857,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008428,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0022603,GO:0030234,GO:0031974,GO:0031981,GO:0032311,GO:0032991,GO:0034641,GO:0034655,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045765,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050790,GO:0050793,GO:0051239,GO:0060255,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0090304,GO:0098772,GO:1901342,GO:1901360,GO:1901361,GO:1901575,GO:2000026	-	ko:K16634	-	-	-	-	ko00000	-	-	-	LRR_6
k59_62314_1	1038860.AXAP01000051_gene5413	4.65e-38	134.0	COG0625@1|root,COG0625@2|Bacteria,1MW27@1224|Proteobacteria,2TUK1@28211|Alphaproteobacteria,3JTJI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	MA20_42385	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
k59_768174_1	744980.TRICHSKD4_2206	1.95e-87	269.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the thiolase family	phbA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_1199585_2	933262.AXAM01000010_gene1391	6.82e-39	138.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2WIMV@28221|Deltaproteobacteria,2MK32@213118|Desulfobacterales	28221|Deltaproteobacteria	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
k59_1081092_1	123899.JPQP01000020_gene1902	1.46e-75	247.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,3T1RJ@506|Alcaligenaceae	28216|Betaproteobacteria	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_420880_2	1121374.KB891586_gene2632	1.05e-27	105.0	COG0776@1|root,COG0776@2|Bacteria,1RFWH@1224|Proteobacteria,1S5GE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the bacterial histone-like protein family	VL23_14575	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
k59_806413_1	903814.ELI_0521	3.25e-42	155.0	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,24AYI@186801|Clostridia,25VXP@186806|Eubacteriaceae	186801|Clostridia	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k59_222433_1	1121405.dsmv_0621	2.3e-74	230.0	COG1028@1|root,COG1028@2|Bacteria,1R7KW@1224|Proteobacteria,42NF5@68525|delta/epsilon subdivisions,2WM4D@28221|Deltaproteobacteria,2MIF5@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
k59_768215_1	177437.HRM2_10900	2.22e-29	114.0	COG2159@1|root,COG2159@2|Bacteria,1Q0A4@1224|Proteobacteria,42Q9N@68525|delta/epsilon subdivisions,2WJTE@28221|Deltaproteobacteria,2MI7C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
k59_298979_1	713587.THITH_02445	1.35e-33	125.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	opsX	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02841,ko:K02849,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
k59_612097_1	1165096.ARWF01000001_gene1813	1.3e-81	253.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,2KKU8@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
k59_1009046_1	9606.ENSP00000346550	7.79e-114	344.0	KOG0819@1|root,KOG0819@2759|Eukaryota,38FEE@33154|Opisthokonta,3BCMH@33208|Metazoa,3CXS1@33213|Bilateria,486J4@7711|Chordata,494WX@7742|Vertebrata,3J803@40674|Mammalia,359XB@314146|Euarchontoglires,4M5VZ@9443|Primates,4N23G@9604|Hominidae	33208|Metazoa	U	Annexin repeats	ANXA6	GO:0000166,GO:0000323,GO:0000910,GO:0001501,GO:0001667,GO:0001725,GO:0001755,GO:0001786,GO:0001882,GO:0001883,GO:0002062,GO:0003413,GO:0003416,GO:0003417,GO:0003418,GO:0003674,GO:0003779,GO:0005215,GO:0005216,GO:0005261,GO:0005262,GO:0005488,GO:0005496,GO:0005515,GO:0005525,GO:0005539,GO:0005543,GO:0005544,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005764,GO:0005765,GO:0005766,GO:0005768,GO:0005770,GO:0005773,GO:0005774,GO:0005819,GO:0005829,GO:0005856,GO:0005886,GO:0005911,GO:0005912,GO:0005924,GO:0005925,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006897,GO:0006909,GO:0006915,GO:0006928,GO:0006937,GO:0007049,GO:0007154,GO:0007165,GO:0007275,GO:0008092,GO:0008150,GO:0008201,GO:0008219,GO:0008289,GO:0008324,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010008,GO:0010035,GO:0010038,GO:0012501,GO:0012505,GO:0012506,GO:0014031,GO:0014032,GO:0014033,GO:0014704,GO:0015075,GO:0015085,GO:0015267,GO:0015276,GO:0015318,GO:0015485,GO:0015629,GO:0015630,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0016324,GO:0016477,GO:0017076,GO:0019001,GO:0019725,GO:0019866,GO:0019899,GO:0022402,GO:0022607,GO:0022803,GO:0022834,GO:0022836,GO:0022838,GO:0022839,GO:0022857,GO:0022890,GO:0023052,GO:0030001,GO:0030003,GO:0030054,GO:0030055,GO:0030061,GO:0030139,GO:0030141,GO:0030154,GO:0030496,GO:0030659,GO:0030667,GO:0031090,GO:0031214,GO:0031224,GO:0031410,GO:0031902,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0031982,GO:0032432,GO:0032501,GO:0032502,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032879,GO:0032934,GO:0032991,GO:0034220,GO:0034702,GO:0034703,GO:0034704,GO:0035265,GO:0035374,GO:0035639,GO:0036094,GO:0038023,GO:0040007,GO:0040011,GO:0042221,GO:0042383,GO:0042470,GO:0042581,GO:0042582,GO:0042583,GO:0042584,GO:0042592,GO:0042641,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043178,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044057,GO:0044085,GO:0044291,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044430,GO:0044433,GO:0044437,GO:0044440,GO:0044444,GO:0044446,GO:0044455,GO:0044459,GO:0044464,GO:0044548,GO:0044877,GO:0045177,GO:0045335,GO:0046873,GO:0046903,GO:0046983,GO:0048306,GO:0048468,GO:0048471,GO:0048513,GO:0048519,GO:0048523,GO:0048589,GO:0048705,GO:0048731,GO:0048762,GO:0048770,GO:0048856,GO:0048863,GO:0048864,GO:0048869,GO:0048870,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051015,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051259,GO:0051260,GO:0051282,GO:0051283,GO:0051301,GO:0051560,GO:0051592,GO:0051674,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0060089,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060485,GO:0061448,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070161,GO:0070509,GO:0070588,GO:0070838,GO:0071840,GO:0071944,GO:0072341,GO:0072503,GO:0072507,GO:0072511,GO:0090257,GO:0097159,GO:0097190,GO:0097367,GO:0097517,GO:0097708,GO:0098588,GO:0098590,GO:0098655,GO:0098657,GO:0098660,GO:0098662,GO:0098771,GO:0098796,GO:0098805,GO:0098852,GO:0098868,GO:0099503,GO:1901265,GO:1901363,GO:1901681,GO:1902495,GO:1990351	-	ko:K17094,ko:K17095	-	-	-	-	ko00000,ko04131,ko04147	1.A.31.1.1,1.A.31.1.2,1.A.31.1.6	-	-	Annexin
k59_337558_1	1267005.KB911257_gene1130	2.91e-125	373.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,2U1NZ@28211|Alphaproteobacteria,3N9J7@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.28,1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058,ko:K03778	ko00260,ko00620,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00620,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00704,R00717,R01388,R01513	RC00031,RC00042,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
k59_924203_1	551275.KB899544_gene916	5.17e-94	299.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2TWVC@28211|Alphaproteobacteria,440R8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_535990_1	553385.JEMF01000016_gene507	1.16e-27	106.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,1XK4R@135619|Oceanospirillales	135619|Oceanospirillales	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
k59_535990_2	1448139.AI20_02735	7.89e-26	105.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1Y3US@135624|Aeromonadales	135624|Aeromonadales	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_180658_1	1120949.KB903328_gene8815	9.06e-92	285.0	COG0366@1|root,COG0366@2|Bacteria,2GN52@201174|Actinobacteria	201174|Actinobacteria	G	Alpha amylase catalytic	amyA	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
k59_1009075_1	1041139.KB902683_gene2761	2.12e-92	290.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_62418_1	713586.KB900536_gene2148	1.94e-53	176.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
k59_964848_1	391038.Bphy_0801	4.32e-72	238.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VM2H@28216|Betaproteobacteria,1K0UN@119060|Burkholderiaceae	28216|Betaproteobacteria	L	helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_1123398_1	109478.XP_005859830.1	1.07e-109	317.0	COG0186@1|root,KOG1728@2759|Eukaryota,39ZXQ@33154|Opisthokonta,3BPBG@33208|Metazoa,3D6CJ@33213|Bilateria,4898G@7711|Chordata,495UN@7742|Vertebrata,3JB4B@40674|Mammalia	33208|Metazoa	J	rRNA binding	RPS11	GO:0000184,GO:0000956,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007275,GO:0007568,GO:0008104,GO:0008150,GO:0008152,GO:0008340,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010259,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015935,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0022626,GO:0022627,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0048856,GO:0050789,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060255,GO:0065007,GO:0070013,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02949	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17,Ribosomal_S17_N
k59_652336_1	61853.ENSNLEP00000013974	9.25e-299	829.0	COG1241@1|root,KOG0482@2759|Eukaryota,38CBW@33154|Opisthokonta,3BDRW@33208|Metazoa,3CUYV@33213|Bilateria,484UH@7711|Chordata,4967C@7742|Vertebrata,3JB2A@40674|Mammalia,35KUZ@314146|Euarchontoglires,4MGFZ@9443|Primates	33208|Metazoa	L	MCM OB domain	MCM7	GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003697,GO:0003824,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009059,GO:0009410,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019220,GO:0019222,GO:0022607,GO:0031323,GO:0031974,GO:0031981,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042325,GO:0042555,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051174,GO:0051276,GO:0051716,GO:0065003,GO:0065007,GO:0070013,GO:0070887,GO:0071103,GO:0071466,GO:0071704,GO:0071840,GO:0072689,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901576	3.6.4.12	ko:K02210	ko03030,ko04110,ko04111,ko04113,map03030,map04110,map04111,map04113	M00285	-	-	ko00000,ko00001,ko00002,ko01000,ko01009,ko03032	-	-	-	MCM,MCM_N,MCM_OB
k59_692407_1	521674.Plim_2712	1.5e-59	199.0	COG0665@1|root,COG0665@2|Bacteria,2IX78@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
k59_64570_1	96561.Dole_2483	4.53e-49	174.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2MIJD@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_1046817_2	1232410.KI421425_gene1551	1.32e-16	76.6	2B4XH@1|root,32REP@2|Bacteria,1PXEZ@1224|Proteobacteria,4305C@68525|delta/epsilon subdivisions,2WVH5@28221|Deltaproteobacteria,43UUP@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_496475_1	243365.CV_3507	2.55e-50	166.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,2KQ1A@206351|Neisseriales	206351|Neisseriales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
k59_496475_2	882378.RBRH_02247	8.86e-30	112.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,1JZY9@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
k59_457032_1	391037.Sare_1890	7.81e-29	112.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4DD25@85008|Micromonosporales	201174|Actinobacteria	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
k59_106201_1	1122947.FR7_2959	2.41e-19	85.5	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	cmoA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
k59_224774_1	177437.HRM2_40980	2.58e-98	313.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,43BJY@68525|delta/epsilon subdivisions,2WIWD@28221|Deltaproteobacteria,2MIG4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdnG-2	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_692454_1	1121405.dsmv_1727	7.78e-55	177.0	COG0461@1|root,COG0461@2|Bacteria,1PI8N@1224|Proteobacteria,42QSR@68525|delta/epsilon subdivisions,2WMT5@28221|Deltaproteobacteria,2MJH0@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
k59_692454_2	1121405.dsmv_1726	1.5e-25	98.2	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,42TJ5@68525|delta/epsilon subdivisions,2WQ2Z@28221|Deltaproteobacteria,2MJT6@213118|Desulfobacterales	28221|Deltaproteobacteria	H	PFAM 6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
k59_457067_1	113395.AXAI01000001_gene3365	2.06e-76	238.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,3JVES@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Malate/L-lactate dehydrogenase	MA20_06110	-	1.1.1.350	ko:K00073,ko:K13574	ko00230,ko01120,map00230,map01120	-	R02935,R02936	RC00169	ko00000,ko00001,ko01000	-	-	-	Ldh_2
k59_301192_1	314278.NB231_01574	1.01e-75	247.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_731339_1	1123504.JQKD01000007_gene3285	8.46e-06	50.4	COG1028@1|root,COG1028@2|Bacteria,1MVKN@1224|Proteobacteria,2VJCW@28216|Betaproteobacteria,4AEES@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
k59_731339_2	861299.J421_5668	8.52e-37	130.0	COG0302@1|root,COG0302@2|Bacteria,1ZT6I@142182|Gemmatimonadetes	2|Bacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659	2.7.6.3,3.5.4.16	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R03503,R04639,R05046,R05048	RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.folE,iIT341.HP0928,iJN678.folE,iNJ661.Rv3609c	GTP_cyclohydroI
k59_25736_1	105559.Nwat_0443	7.59e-70	218.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1WX5A@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_25751_1	1125863.JAFN01000001_gene2707	1.33e-81	257.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_808495_1	207559.Dde_3040	1.74e-59	199.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42ME4@68525|delta/epsilon subdivisions,2WJA5@28221|Deltaproteobacteria,2MA0T@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_496548_1	998674.ATTE01000001_gene1952	3e-66	223.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,462CG@72273|Thiotrichales	72273|Thiotrichales	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel,MscS_TM
k59_1011292_1	557598.LHK_00527	0.000842	40.4	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,2KR3H@206351|Neisseriales	206351|Neisseriales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
k59_379851_1	384765.SIAM614_02541	2.14e-16	78.6	COG1289@1|root,COG1289@2|Bacteria	2|Bacteria	S	transmembrane transporter activity	VPA1578	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_888380_2	414684.RC1_0412	3.09e-25	104.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2JPYX@204441|Rhodospirillales	204441|Rhodospirillales	I	COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
k59_1123496_1	118797.XP_007448859.1	1.03e-154	460.0	COG1643@1|root,KOG0925@2759|Eukaryota,3API8@33154|Opisthokonta,3CNW1@33208|Metazoa,3E522@33213|Bilateria,487F6@7711|Chordata,48UU9@7742|Vertebrata,3J57K@40674|Mammalia,4J7TU@91561|Cetartiodactyla	33208|Metazoa	A	helicase 15	DHX15	GO:0000375,GO:0000377,GO:0000398,GO:0001932,GO:0001934,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005689,GO:0005730,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0008380,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010467,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0016070,GO:0016071,GO:0016072,GO:0016462,GO:0016604,GO:0016607,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019220,GO:0019222,GO:0022613,GO:0023051,GO:0023056,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032872,GO:0032874,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042325,GO:0042327,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043408,GO:0043410,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0045937,GO:0046483,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051174,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070013,GO:0070035,GO:0070302,GO:0070304,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0140098,GO:1900744,GO:1900745,GO:1901360,GO:1901363,GO:1902531,GO:1902533,GO:1990904	3.6.4.13	ko:K12820,ko:K14305	ko03013,ko03040,map03013,map03040	M00427	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019,ko03036,ko03041	1.l.1	-	-	DEAD,HA2,Helicase_C,OB_NTP_bind
k59_25782_2	1121937.AUHJ01000021_gene1432	8.37e-73	228.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,1RR0T@1236|Gammaproteobacteria,46BKC@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
k59_692533_1	997296.PB1_12774	9.99e-15	76.3	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HJ7Y@91061|Bacilli,1ZGH8@1386|Bacillus	91061|Bacilli	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_770544_1	317936.Nos7107_2202	2.67e-74	240.0	COG0402@1|root,COG0402@2|Bacteria,1GCK3@1117|Cyanobacteria,1HS6K@1161|Nostocales	1117|Cyanobacteria	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
k59_1083392_1	1304872.JAGC01000009_gene342	2.21e-61	202.0	COG4671@1|root,COG4671@2|Bacteria,1N1PQ@1224|Proteobacteria,42MDW@68525|delta/epsilon subdivisions,2WKQK@28221|Deltaproteobacteria,2M92X@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Glycosyltransferase 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k59_106365_1	1123360.thalar_00290	8.09e-54	182.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
k59_143223_1	379731.PST_0561	1.57e-68	233.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1Z0JD@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	COG0067 Glutamate synthase domain 1	gltB	GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1123536_2	269799.Gmet_1181	5.61e-44	151.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
k59_1245224_1	460265.Mnod_2841	1.57e-52	185.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,1JTFA@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase type 2 domain	mmgC	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249,ko:K20035	ko00071,ko00280,ko00410,ko00640,ko00650,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map00920,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R11130	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246,RC03363	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_457172_1	402881.Plav_1428	1.24e-13	72.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,1JNJH@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	citE	-	3.1.2.30,4.1.3.34	ko:K01644,ko:K14451	ko00630,ko01120,ko01200,ko02020,map00630,map01120,map01200,map02020	M00373	R00362,R10612	RC00004,RC00014,RC00067,RC01118	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
k59_457172_2	1231185.BAMP01000033_gene824	4.21e-30	111.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2U7FW@28211|Alphaproteobacteria,43JJT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k59_143237_1	1040989.AWZU01000040_gene6008	8.69e-47	156.0	COG0454@1|root,COG0456@2|Bacteria,1RIAQ@1224|Proteobacteria,2UEAD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
k59_614420_1	1168065.DOK_13889	7.96e-75	237.0	COG2270@1|root,COG2270@2|Bacteria,1QUVA@1224|Proteobacteria,1T226@1236|Gammaproteobacteria,1J5K8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0477 Permeases of the major facilitator superfamily	Z012_03780	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
k59_379951_1	1279017.AQYJ01000028_gene2269	3.59e-176	506.0	COG0654@1|root,COG0654@2|Bacteria,1NSGN@1224|Proteobacteria,1T22A@1236|Gammaproteobacteria,46505@72275|Alteromonadaceae	1236|Gammaproteobacteria	CH	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
k59_849057_1	28229.ND2E_2630	1.7e-33	129.0	COG2204@1|root,COG2204@2|Bacteria,1MWW5@1224|Proteobacteria,1RND4@1236|Gammaproteobacteria,2Q5MH@267889|Colwelliaceae	1236|Gammaproteobacteria	T	Bacterial regulatory protein, Fis family	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
k59_539064_1	335543.Sfum_1181	1.45e-66	218.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_539064_2	335543.Sfum_1182	0.000616	41.2	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
k59_496640_1	42565.FP66_15280	1.12e-28	112.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,1XHIT@135619|Oceanospirillales	135619|Oceanospirillales	EP	(ABC) transporter, permease	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_496640_2	1379281.AVAG01000041_gene849	1.2e-76	237.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,42P18@68525|delta/epsilon subdivisions,2WJNV@28221|Deltaproteobacteria,2M9JP@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_1229097_2	1122197.ATWI01000011_gene287	9.84e-22	97.8	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,4658B@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
k59_248031_1	710111.FraQA3DRAFT_5943	7.52e-17	81.6	COG2310@1|root,COG2340@1|root,COG2310@2|Bacteria,COG2340@2|Bacteria,2GNN0@201174|Actinobacteria	201174|Actinobacteria	T	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,TerD
k59_248031_2	211165.AJLN01000116_gene3146	2.79e-05	51.2	COG2931@1|root,COG3266@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,1G5GU@1117|Cyanobacteria,1JKDH@1189|Stigonemataceae	1117|Cyanobacteria	Q	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_12619_1	30611.ENSOGAP00000014549	3.86e-150	424.0	COG2125@1|root,KOG1646@2759|Eukaryota,38HEM@33154|Opisthokonta,3BD3X@33208|Metazoa,3CUHH@33213|Bilateria,47ZXA@7711|Chordata,48XNW@7742|Vertebrata,3J7XU@40674|Mammalia,35JHG@314146|Euarchontoglires,4MGH1@9443|Primates	33208|Metazoa	J	Belongs to the eukaryotic ribosomal protein eS6 family	RPS6	GO:0000003,GO:0000028,GO:0000075,GO:0000082,GO:0000184,GO:0000278,GO:0000956,GO:0001775,GO:0001776,GO:0001890,GO:0002181,GO:0002252,GO:0002260,GO:0002262,GO:0002263,GO:0002285,GO:0002286,GO:0002309,GO:0002366,GO:0002376,GO:0002520,GO:0002521,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005783,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006915,GO:0006924,GO:0006955,GO:0006996,GO:0007049,GO:0007093,GO:0007154,GO:0007165,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007346,GO:0007369,GO:0007568,GO:0008104,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008340,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009892,GO:0009987,GO:0010033,GO:0010243,GO:0010259,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0010941,GO:0010942,GO:0012501,GO:0012505,GO:0015031,GO:0015833,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0019222,GO:0019439,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0022605,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0023052,GO:0030097,GO:0030098,GO:0030099,GO:0030154,GO:0030217,GO:0030218,GO:0030425,GO:0031929,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032868,GO:0032943,GO:0032991,GO:0033036,GO:0033077,GO:0033365,GO:0033500,GO:0034101,GO:0034470,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0035556,GO:0035690,GO:0035770,GO:0036464,GO:0036477,GO:0042098,GO:0042110,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0042493,GO:0042592,GO:0042593,GO:0042886,GO:0042981,GO:0042995,GO:0043005,GO:0043029,GO:0043043,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043434,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044297,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044463,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044843,GO:0045047,GO:0045184,GO:0045321,GO:0045471,GO:0045786,GO:0045930,GO:0046483,GO:0046649,GO:0046651,GO:0046677,GO:0046700,GO:0046907,GO:0048468,GO:0048471,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048598,GO:0048608,GO:0048609,GO:0048731,GO:0048821,GO:0048856,GO:0048869,GO:0048872,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0051726,GO:0060255,GO:0060548,GO:0061458,GO:0061515,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070227,GO:0070231,GO:0070661,GO:0070727,GO:0070887,GO:0070925,GO:0070972,GO:0071236,GO:0071310,GO:0071361,GO:0071702,GO:0071704,GO:0071705,GO:0071826,GO:0071840,GO:0071887,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097447,GO:0097458,GO:0120025,GO:0120038,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901652,GO:1901698,GO:1901700,GO:1901701,GO:1901888,GO:1901889,GO:1903047,GO:1903347,GO:1990904,GO:2000810	-	ko:K02991	ko01521,ko03010,ko04066,ko04150,ko04151,ko04371,ko04714,ko04910,ko05205,map01521,map03010,map04066,map04150,map04151,map04371,map04714,map04910,map05205	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S6e
k59_208508_1	1408445.JHXP01000028_gene3096	4.87e-06	55.8	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1JDD0@118969|Legionellales	118969|Legionellales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_7,PAS_8,Response_reg
k59_639597_1	335543.Sfum_0108	3.78e-117	354.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria,2MSIT@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	AMP-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
k59_994211_1	1232437.KL662057_gene3906	2.11e-74	233.0	COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,42NTF@68525|delta/epsilon subdivisions,2X75Q@28221|Deltaproteobacteria,2MITK@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
k59_326059_1	335283.Neut_0816	5.92e-42	152.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria,372N4@32003|Nitrosomonadales	28216|Betaproteobacteria	P	von Willebrand factor, type A	cbbO	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
k59_326059_2	323098.Nwi_1974	9.77e-98	288.0	COG4577@1|root,COG4577@2|Bacteria,1QG1Y@1224|Proteobacteria,2UBI7@28211|Alphaproteobacteria,3K477@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
k59_1070307_1	468059.AUHA01000002_gene563	1.26e-05	52.4	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
k59_130270_1	536019.Mesop_0888	1.46e-15	77.8	COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,1MUBE@1224|Proteobacteria,2TT3E@28211|Alphaproteobacteria,43NW9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
k59_13689_1	1417296.U879_08090	2.99e-47	160.0	COG1150@1|root,COG1150@2|Bacteria,1R874@1224|Proteobacteria,2U3QM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_9
k59_13689_2	1417296.U879_08095	1.49e-08	54.7	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2U4AQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
k59_836540_2	207954.MED92_01159	1.13e-65	208.0	COG1192@1|root,COG1192@2|Bacteria,1MVEZ@1224|Proteobacteria,1RPWA@1236|Gammaproteobacteria,1XI4F@135619|Oceanospirillales	135619|Oceanospirillales	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_914419_1	565045.NOR51B_912	1.01e-08	55.5	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_914419_2	545276.KB898730_gene1390	1.27e-46	160.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1WX0P@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_444814_1	288000.BBta_4127	4.68e-108	318.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2TRCB@28211|Alphaproteobacteria,3JR3N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source	acdS	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
k59_1111002_1	314230.DSM3645_20592	1.2e-32	130.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2IY1G@203682|Planctomycetes	203682|Planctomycetes	P	COG0038 Chloride channel protein EriC	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
k59_1035147_1	1279038.KB907343_gene2391	4.72e-56	187.0	COG4111@1|root,COG4111@2|Bacteria,1MXHA@1224|Proteobacteria,2TQQU@28211|Alphaproteobacteria,2JQV4@204441|Rhodospirillales	204441|Rhodospirillales	F	belongs to the nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_758063_1	1449049.JONW01000005_gene1812	2.82e-07	56.2	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2U26R@28211|Alphaproteobacteria,2KEYV@204458|Caulobacterales	204458|Caulobacterales	M	AsmA family	-	-	-	ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA
k59_1230618_1	160492.XF_0868	1.14e-57	197.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1X3MV@135614|Xanthomonadales	135614|Xanthomonadales	C	dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
k59_407294_1	580332.Slit_2403	8.5e-21	86.7	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,44VPP@713636|Nitrosomonadales	28216|Betaproteobacteria	E	ACT domain	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
k59_407294_2	666685.R2APBS1_3658	5.74e-27	108.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1X45G@135614|Xanthomonadales	135614|Xanthomonadales	E	Acetolactate synthase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_1035183_1	1244869.H261_07618	7.68e-18	88.2	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWEB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07716	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_7
k59_836573_1	96561.Dole_2078	4.21e-79	242.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,2MJM4@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
k59_797005_1	384765.SIAM614_02596	9.83e-81	256.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_1230653_1	1232437.KL662040_gene2136	8.61e-80	251.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_523595_2	1056820.KB900630_gene1413	3.71e-86	257.0	COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria,1RMWV@1236|Gammaproteobacteria,2PN0D@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	C	Rnf-Nqr subunit, membrane protein	nqrE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
k59_875748_1	1122951.ATUE01000006_gene1498	1.21e-86	277.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,3NIPR@468|Moraxellaceae	1236|Gammaproteobacteria	I	Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate	fadB	GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8	ko:K01782,ko:K01825	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_0614,iNRG857_1313.NRG857_19200	3HCDH,3HCDH_N,ECH_1
k59_444868_1	501479.ACNW01000081_gene4633	5.67e-86	270.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_995779_1	358681.BBR47_15580	2.55e-56	186.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,26QZ3@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439,M00566	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.2,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k59_995779_2	797302.Halru_2335	9.75e-12	63.9	COG1173@1|root,arCOG00748@2157|Archaea,2XUIX@28890|Euryarchaeota,23T5H@183963|Halobacteria	183963|Halobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	nikC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_1189517_1	439235.Dalk_2552	1.4e-27	115.0	COG5421@1|root,COG5421@2|Bacteria,1R6MI@1224|Proteobacteria,42U8I@68525|delta/epsilon subdivisions,2WQCY@28221|Deltaproteobacteria,2MNWM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_52783_1	1280953.HOC_07188	1.56e-26	114.0	COG3710@1|root,COG5616@1|root,COG3710@2|Bacteria,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,2TWZ1@28211|Alphaproteobacteria,44159@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Trans_reg_C
k59_131357_1	644282.Deba_1073	1.32e-42	153.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_131357_2	335543.Sfum_1238	1.54e-42	151.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2MQS8@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
k59_1035261_1	387631.Asulf_02173	1.58e-11	71.2	COG0582@1|root,arCOG01241@2157|Archaea,2XUBA@28890|Euryarchaeota	28890|Euryarchaeota	L	integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_1035283_1	1535422.ND16A_3185	6.82e-57	199.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q7E9@267889|Colwelliaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_484184_1	1354722.JQLS01000008_gene3720	2.92e-50	176.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2TRQ2@28211|Alphaproteobacteria,46PTC@74030|Roseovarius	28211|Alphaproteobacteria	CP	COG0651 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	phaD	-	-	ko:K05561	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Proton_antipo_M
k59_875819_2	751994.AGIG01000017_gene55	1.12e-38	135.0	COG0457@1|root,COG0457@2|Bacteria,1QZ3D@1224|Proteobacteria	1224|Proteobacteria	S	Putative 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5
k59_1111116_1	1453501.JELR01000002_gene1535	2.57e-11	65.5	2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,467DY@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1071441_1	1379270.AUXF01000006_gene71	3.61e-29	119.0	COG0608@1|root,COG0608@2|Bacteria,1ZTGC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_562459_1	342113.DM82_4060	6.26e-63	209.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VKC1@28216|Betaproteobacteria,1K4WV@119060|Burkholderiaceae	28216|Betaproteobacteria	C	e3 binding domain	bkdB	-	2.3.1.168	ko:K09699	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R02662,R03174,R04097,R10998	RC00004,RC02727,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
k59_640774_2	1218352.B597_015915	4.11e-08	56.2	COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1SX1M@1236|Gammaproteobacteria,1Z3JE@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	NU	Type IV Pilus-assembly protein W	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
k59_1035342_1	1469245.JFBG01000077_gene319	1.36e-17	76.3	COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,1S8SI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	IV02_17390	-	-	ko:K09948	-	-	-	-	ko00000	-	-	-	DUF1244
k59_562498_1	439235.Dalk_4262	2.26e-34	135.0	COG0664@1|root,COG1033@1|root,COG2199@1|root,COG0664@2|Bacteria,COG1033@2|Bacteria,COG3706@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2MJQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	K	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	GGDEF,LolA_like,MMPL,cNMP_binding
k59_1150146_1	525246.HMPREF0058_1167	8.82e-18	87.0	COG1397@1|root,COG1397@2|Bacteria,2GMYG@201174|Actinobacteria	201174|Actinobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
k59_797129_1	9606.ENSP00000252593	6.11e-97	285.0	2D8PF@1|root,2TB0V@2759|Eukaryota,3ANPM@33154|Opisthokonta,3C1N9@33208|Metazoa,3D9SK@33213|Bilateria,48G1S@7711|Chordata,49CTA@7742|Vertebrata,3JHZN@40674|Mammalia,35QVE@314146|Euarchontoglires,4MMXS@9443|Primates,4N400@9604|Hominidae	33208|Metazoa	U	Bone marrow stromal antigen 2	BST2	GO:0000323,GO:0001558,GO:0001775,GO:0001817,GO:0001818,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002683,GO:0002697,GO:0002698,GO:0002700,GO:0002701,GO:0002703,GO:0002704,GO:0002718,GO:0002719,GO:0002730,GO:0002731,GO:0002736,GO:0002737,GO:0003674,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005765,GO:0005766,GO:0005768,GO:0005770,GO:0005771,GO:0005773,GO:0005774,GO:0005794,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0008150,GO:0008191,GO:0008283,GO:0009605,GO:0009607,GO:0009615,GO:0009892,GO:0009986,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0012506,GO:0016020,GO:0016021,GO:0016192,GO:0016324,GO:0019221,GO:0019222,GO:0023052,GO:0030141,GO:0030162,GO:0030234,GO:0030308,GO:0030334,GO:0030336,GO:0030414,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031410,GO:0031982,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032879,GO:0032940,GO:0032956,GO:0032970,GO:0033043,GO:0034097,GO:0034340,GO:0034341,GO:0035455,GO:0035456,GO:0035577,GO:0036230,GO:0040008,GO:0040012,GO:0040013,GO:0042119,GO:0042221,GO:0042582,GO:0042802,GO:0042803,GO:0043086,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043299,GO:0043312,GO:0043900,GO:0043901,GO:0043903,GO:0044092,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045055,GO:0045069,GO:0045071,GO:0045087,GO:0045177,GO:0045321,GO:0045861,GO:0045926,GO:0046903,GO:0046983,GO:0048519,GO:0048523,GO:0048525,GO:0048583,GO:0048585,GO:0048856,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050792,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051248,GO:0051270,GO:0051271,GO:0051336,GO:0051346,GO:0051493,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0052547,GO:0052548,GO:0060255,GO:0060337,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070887,GO:0071310,GO:0071345,GO:0071357,GO:0071944,GO:0080090,GO:0097708,GO:0098542,GO:0098588,GO:0098590,GO:0098772,GO:0098805,GO:0098852,GO:0099503,GO:1901252,GO:1901253,GO:1903900,GO:1903901,GO:2000145,GO:2000146	-	ko:K06731	-	-	-	-	ko00000,ko04090	-	-	-	BST2
k59_995946_1	56780.SYN_02874	5.21e-46	157.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,42M1U@68525|delta/epsilon subdivisions,2WKK5@28221|Deltaproteobacteria,2MRYB@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	pfkB family carbohydrate kinase	-	-	2.7.1.15,2.7.1.4	ko:K00847,ko:K00852	ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100	-	R00760,R00867,R01051,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
k59_995946_2	1121445.ATUZ01000015_gene1755	1.26e-13	67.4	2C9KR@1|root,32RPF@2|Bacteria,1MZXP@1224|Proteobacteria,42UJQ@68525|delta/epsilon subdivisions,2WQ5C@28221|Deltaproteobacteria,2MBEN@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_680082_1	335543.Sfum_3097	6.42e-122	376.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MR0U@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_875889_1	717785.HYPMC_0768	2.61e-07	51.2	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,3N6KQ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	T	Sigma-54 interaction domain	tacA	GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat
k59_995962_1	670292.JH26_13535	7.59e-54	182.0	COG2223@1|root,COG2223@2|Bacteria,1MXAA@1224|Proteobacteria,2TS5Z@28211|Alphaproteobacteria,1JSM6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Major Facilitator Superfamily	fsr	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
k59_680111_1	439235.Dalk_0567	2.55e-71	227.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MXG@68525|delta/epsilon subdivisions,2WJ6G@28221|Deltaproteobacteria,2MJ69@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_758271_1	1121405.dsmv_2273	4.29e-46	156.0	COG2823@1|root,COG2823@2|Bacteria,1Q1QW@1224|Proteobacteria,42U7A@68525|delta/epsilon subdivisions,2X5PY@28221|Deltaproteobacteria,2MKM2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	BON domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
k59_914634_1	1278309.KB907100_gene1849	2.25e-19	84.0	COG3152@1|root,COG3152@2|Bacteria,1QECQ@1224|Proteobacteria,1SHDJ@1236|Gammaproteobacteria,1XPWC@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
k59_367080_2	69395.JQLZ01000009_gene1941	5.71e-36	130.0	COG3832@1|root,COG3832@2|Bacteria,1N2PR@1224|Proteobacteria,2VGJB@28211|Alphaproteobacteria,2KJ19@204458|Caulobacterales	204458|Caulobacterales	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
k59_1189674_1	1120956.JHZK01000001_gene3417	1.7e-38	144.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,2TUSJ@28211|Alphaproteobacteria,1JNHH@119043|Rhodobiaceae	28211|Alphaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
k59_1230925_1	1040989.AWZU01000018_gene2759	4.31e-29	114.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2TRTW@28211|Alphaproteobacteria,3JTYP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
k59_93274_1	1552758.NC00_03995	1.56e-45	165.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1X39Z@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_249358_1	1232437.KL662006_gene4387	1.93e-46	152.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	pkn5	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	AAA_16,GAF,HAMP,Pkinase,Response_reg,SpoIIE,dCache_1
k59_209972_1	225937.HP15_802	2.31e-16	82.4	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,1RM7K@1236|Gammaproteobacteria,464AD@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iECs_1301.ECs5024,iG2583_1286.G2583_4866	Acyltransferase
k59_407595_1	290400.Jann_3121	2.73e-10	60.5	COG0069@1|root,COG4638@1|root,COG0069@2|Bacteria,COG4638@2|Bacteria,1MU7B@1224|Proteobacteria,2TRWC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rieske,zf-CDGSH
k59_1189726_1	1254432.SCE1572_17685	1.74e-57	201.0	COG0515@1|root,COG2203@1|root,COG3829@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YI@28221|Deltaproteobacteria,2YTVN@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Pkinase,PocR,Sigma54_activat
k59_249386_1	999549.KI421513_gene745	1.8e-21	93.2	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2808W@191028|Leisingera	28211|Alphaproteobacteria	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k59_249386_2	1453505.JASY01000019_gene4765	5.38e-10	62.8	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia,2NSP5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1150239_1	755731.Clo1100_2782	1.14e-128	436.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	ko:K13611	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
k59_996088_1	335543.Sfum_1184	2.26e-56	195.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1PFB9@1224|Proteobacteria,437WC@68525|delta/epsilon subdivisions,2X35Z@28221|Deltaproteobacteria,2MS2F@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_445093_1	411902.CLOBOL_06481	3.61e-14	77.0	COG5441@1|root,COG5441@2|Bacteria,1TQ3W@1239|Firmicutes,24A9D@186801|Clostridia,21YQY@1506553|Lachnoclostridium	186801|Clostridia	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
k59_1231013_1	671143.DAMO_2574	1.3e-28	114.0	COG1427@1|root,COG1427@2|Bacteria,2NRPR@2323|unclassified Bacteria	2|Bacteria	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	1.21.98.1,4.2.1.151	ko:K07081,ko:K11782,ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588,R10666	RC02329,RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
k59_1189770_1	1121405.dsmv_2971	2.98e-111	334.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42N1X@68525|delta/epsilon subdivisions,2WKMS@28221|Deltaproteobacteria,2MIZN@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase MttB (TMA methyltransferase)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
k59_758373_1	713586.KB900536_gene2604	5.11e-57	191.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1WXB2@135613|Chromatiales	135613|Chromatiales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
k59_249439_1	1511.CLOST_1951	2.26e-26	112.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,25R50@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
k59_1035576_1	379731.PST_0562	4.22e-25	105.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1YZYR@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iEC042_1314.EC042_3503,iYL1228.KPN_03625	Fer4_11,Fer4_20,Pyr_redox_2
k59_996154_1	1123371.ATXH01000008_gene262	2.91e-75	239.0	COG0337@1|root,COG0337@2|Bacteria,2GGYX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
k59_719894_2	1198114.AciX9_2245	1.8e-13	68.6	COG2963@1|root,COG2963@2|Bacteria,3Y86J@57723|Acidobacteria,2JN6K@204432|Acidobacteriia	204432|Acidobacteriia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
k59_719894_3	478801.Ksed_22000	1.75e-10	61.6	COG2801@1|root,COG2801@2|Bacteria,2HBU8@201174|Actinobacteria	201174|Actinobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_719895_1	1121405.dsmv_3708	9.76e-97	295.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,2MI1E@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
k59_88726_1	1294273.roselon_03311	2.96e-92	286.0	COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,2TRQ9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA ligase	lig	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
k59_636619_1	335543.Sfum_2378	3.83e-95	292.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2WKAN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
k59_283810_1	292459.STH3148	3.31e-16	78.2	COG1290@1|root,COG1290@2|Bacteria,1TP6M@1239|Firmicutes,24K8U@186801|Clostridia	186801|Clostridia	C	Cytochrome b subunit of the bc	-	-	-	ko:K00412,ko:K02635	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrome_B
k59_519299_2	1121085.AUCI01000002_gene4021	6.03e-18	76.6	29SGJ@1|root,30DMJ@2|Bacteria,1UBFB@1239|Firmicutes,4IMU0@91061|Bacilli,1ZKUH@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_519299_3	644282.Deba_3157	1.54e-41	142.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,42V63@68525|delta/epsilon subdivisions,2WQCH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	TIGRFAM transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
k59_715290_1	61622.XP_010350986.1	1.24e-133	390.0	COG5188@1|root,KOG2636@2759|Eukaryota,38G63@33154|Opisthokonta,3B98V@33208|Metazoa,3D1IF@33213|Bilateria,48545@7711|Chordata,48XXV@7742|Vertebrata,3J8NH@40674|Mammalia,35HG9@314146|Euarchontoglires,4M5YB@9443|Primates,364GF@314294|Cercopithecoidea	33208|Metazoa	A	Splicing factor 3A subunit 3	SF3A3	GO:0000003,GO:0000245,GO:0000375,GO:0000377,GO:0000389,GO:0000398,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005686,GO:0006139,GO:0006376,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009566,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016071,GO:0016604,GO:0016607,GO:0019953,GO:0022414,GO:0022607,GO:0022613,GO:0022618,GO:0030532,GO:0031974,GO:0031981,GO:0032991,GO:0034622,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044703,GO:0046483,GO:0051704,GO:0065003,GO:0070013,GO:0071013,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097525,GO:0120114,GO:1901360,GO:1901363,GO:1902494,GO:1990904	-	ko:K12827	ko03040,map03040	M00352	-	-	ko00000,ko00001,ko00002,ko03041	-	-	-	DUF3449,SF3A3,SF3a60_bindingd,Telomere_Sde2_2
k59_323005_1	323261.Noc_0180	2.12e-87	273.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1WVVK@135613|Chromatiales	135613|Chromatiales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
k59_871409_2	572477.Alvin_1026	2.84e-09	58.5	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1WWAI@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
k59_1029489_1	318167.Sfri_1866	3.47e-42	154.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,1RQJ9@1236|Gammaproteobacteria,2QA8V@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
k59_323012_1	1265505.ATUG01000002_gene1024	1.79e-33	129.0	COG4671@1|root,COG4671@2|Bacteria,1NE6T@1224|Proteobacteria,42M07@68525|delta/epsilon subdivisions,2WJA3@28221|Deltaproteobacteria,2MHTF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
k59_558139_1	589873.EP13_00780	6.32e-109	335.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,1RMH5@1236|Gammaproteobacteria,46A0S@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Arginase family	speB	-	3.5.3.1,3.5.3.11,3.5.3.8	ko:K01476,ko:K01479,ko:K01480	ko00220,ko00330,ko00340,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map00340,map01100,map01110,map01130,map01230,map05146	M00029,M00045,M00133,M00134	R00551,R01157,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
k59_88784_1	1121405.dsmv_2105	1.76e-99	307.0	COG0427@1|root,COG0454@1|root,COG0427@2|Bacteria,COG0456@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
k59_401914_1	1453501.JELR01000002_gene346	1.59e-67	213.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,1RRWP@1236|Gammaproteobacteria,465RQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	COG0811 Biopolymer transport proteins	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
k59_205427_1	557599.MKAN_22705	2.11e-06	50.4	COG2124@1|root,COG2124@2|Bacteria,2GJ3T@201174|Actinobacteria,23402@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
k59_205427_2	907348.TresaDRAFT_1594	7.69e-47	158.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
k59_362741_1	504832.OCAR_6063	1.78e-11	70.5	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2TSB6@28211|Alphaproteobacteria,3JR4W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA	-	-	ko:K07799,ko:K18990	ko02020,map02020	M00648,M00720	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2.30,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_49022_1	335543.Sfum_2756	4.85e-59	202.0	COG0707@1|root,COG1413@1|root,COG0707@2|Bacteria,COG1413@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2MRPC@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
k59_88794_1	768671.ThimaDRAFT_4614	6.98e-88	288.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1WX8F@135613|Chromatiales	135613|Chromatiales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
k59_871458_1	1384054.N790_01925	1.19e-41	153.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1X48I@135614|Xanthomonadales	135614|Xanthomonadales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k59_244970_1	977880.RALTA_B1651	0.000114	48.9	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2VKTZ@28216|Betaproteobacteria,1K02I@119060|Burkholderiaceae	28216|Betaproteobacteria	P	transporter	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
k59_1029553_1	1158292.JPOE01000005_gene815	2.77e-12	70.5	COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,2VTMV@28216|Betaproteobacteria,1KNC3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
k59_558185_1	1232437.KL662001_gene4624	2.21e-88	279.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MHKH@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_9756_1	751994.AGIG01000009_gene1058	5.08e-13	64.7	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1JATU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
k59_9756_2	545276.KB898725_gene724	1.56e-46	166.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_166496_1	1037409.BJ6T_21760	2.01e-32	123.0	2C2X7@1|root,31WBU@2|Bacteria,1P2EC@1224|Proteobacteria,2UV16@28211|Alphaproteobacteria,3JWR5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF4239)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
k59_49060_3	1232437.KL662040_gene2136	5.15e-81	256.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_401972_1	279714.FuraDRAFT_3273	2.53e-23	99.4	COG3318@1|root,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,2VSZR@28216|Betaproteobacteria,2KSX6@206351|Neisseriales	206351|Neisseriales	S	Uncharacterised protein family (UPF0149)	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	UPF0149
k59_9769_1	1121875.KB907549_gene1715	3.13e-11	64.7	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,TPR_8
k59_9769_2	382464.ABSI01000012_gene2201	5.34e-08	53.9	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C
k59_715434_1	9606.ENSP00000353720	1.2e-105	320.0	COG2272@1|root,KOG1516@2759|Eukaryota,38D2A@33154|Opisthokonta,3BDJX@33208|Metazoa,3CTBY@33213|Bilateria,485ZR@7711|Chordata,48Y85@7742|Vertebrata,3J3G7@40674|Mammalia,35D4R@314146|Euarchontoglires,4M8P6@9443|Primates,4MTE2@9604|Hominidae	33208|Metazoa	I	Carboxylesterase family	CES1	GO:0000003,GO:0000902,GO:0000904,GO:0001941,GO:0003674,GO:0003824,GO:0004771,GO:0004806,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005811,GO:0005829,GO:0005886,GO:0005887,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006638,GO:0006639,GO:0006690,GO:0006692,GO:0006693,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006805,GO:0006807,GO:0006810,GO:0006869,GO:0006897,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0007155,GO:0007158,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007416,GO:0007610,GO:0007617,GO:0007618,GO:0008037,GO:0008038,GO:0008039,GO:0008045,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009410,GO:0009605,GO:0009607,GO:0009636,GO:0009653,GO:0009888,GO:0009986,GO:0009987,GO:0010468,GO:0010646,GO:0010876,GO:0010984,GO:0012505,GO:0015850,GO:0015918,GO:0016020,GO:0016021,GO:0016042,GO:0016043,GO:0016054,GO:0016125,GO:0016126,GO:0016192,GO:0016201,GO:0016289,GO:0016290,GO:0016298,GO:0016482,GO:0016787,GO:0016788,GO:0016790,GO:0019098,GO:0019216,GO:0019222,GO:0019626,GO:0019637,GO:0019693,GO:0019752,GO:0019953,GO:0022008,GO:0022414,GO:0022607,GO:0022610,GO:0023051,GO:0030030,GO:0030154,GO:0030182,GO:0030301,GO:0030431,GO:0030855,GO:0031012,GO:0031175,GO:0031224,GO:0031226,GO:0031323,GO:0031974,GO:0032365,GO:0032366,GO:0032367,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032989,GO:0032990,GO:0033036,GO:0033559,GO:0033865,GO:0033875,GO:0034032,GO:0034377,GO:0034378,GO:0034379,GO:0034641,GO:0035383,GO:0036465,GO:0040011,GO:0042043,GO:0042221,GO:0042330,GO:0043062,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0045202,GO:0046165,GO:0046395,GO:0046459,GO:0046461,GO:0046464,GO:0046483,GO:0046486,GO:0046503,GO:0046907,GO:0047617,GO:0048468,GO:0048488,GO:0048609,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050794,GO:0050804,GO:0050808,GO:0050896,GO:0050919,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051641,GO:0051649,GO:0051704,GO:0051707,GO:0051716,GO:0051791,GO:0052689,GO:0055086,GO:0060179,GO:0060255,GO:0060429,GO:0061024,GO:0061564,GO:0062023,GO:0065003,GO:0065005,GO:0065007,GO:0070013,GO:0070887,GO:0071466,GO:0071702,GO:0071704,GO:0071709,GO:0071825,GO:0071827,GO:0071840,GO:0071944,GO:0072329,GO:0072521,GO:0080090,GO:0090119,GO:0090122,GO:0090207,GO:0090320,GO:0097006,GO:0097090,GO:0097104,GO:0097105,GO:0097485,GO:0098542,GO:0098609,GO:0098657,GO:0099003,GO:0099054,GO:0099068,GO:0099172,GO:0099173,GO:0099177,GO:0099504,GO:0120036,GO:0120039,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901568,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653	3.1.1.1,3.1.1.56,3.1.1.59,3.1.1.7,3.1.1.8,3.1.1.84	ko:K01044,ko:K01049,ko:K01050,ko:K01063,ko:K03927,ko:K07378,ko:K14999,ko:K15743	ko00564,ko00981,ko00983,ko01100,ko04514,ko04725,map00564,map00981,map00983,map01100,map04514,map04725	-	R01026,R06728,R08149,R08150,R08220,R08249,R08251,R08255,R08258	RC00020,RC00041,RC00055,RC00162,RC00460,RC00461,RC00475,RC00476,RC00523,RC00962,RC02264	ko00000,ko00001,ko00199,ko00537,ko01000,ko04131,ko04516	-	CE10	-	COesterase
k59_1145937_1	1026970.XP_008823581.1	1.5e-110	324.0	COG0330@1|root,KOG3090@2759|Eukaryota,38CCG@33154|Opisthokonta,3B9IP@33208|Metazoa,3CRDP@33213|Bilateria,489QQ@7711|Chordata,48Z03@7742|Vertebrata,3J64U@40674|Mammalia,35H2V@314146|Euarchontoglires,4PV2H@9989|Rodentia	33208|Metazoa	K	Prohibitin-2	PHB2	GO:0000003,GO:0000060,GO:0000819,GO:0001101,GO:0001666,GO:0001763,GO:0001932,GO:0001934,GO:0002009,GO:0002082,GO:0003006,GO:0003008,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005743,GO:0006140,GO:0006355,GO:0006606,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006851,GO:0006886,GO:0006913,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0007049,GO:0007059,GO:0007062,GO:0007088,GO:0007096,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007292,GO:0007346,GO:0007548,GO:0007588,GO:0008022,GO:0008104,GO:0008134,GO:0008150,GO:0008285,GO:0008406,GO:0009611,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010558,GO:0010562,GO:0010564,GO:0010604,GO:0010605,GO:0010629,GO:0010638,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016363,GO:0017038,GO:0019219,GO:0019220,GO:0019222,GO:0019866,GO:0019867,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0022603,GO:0022612,GO:0023051,GO:0023056,GO:0023057,GO:0030001,GO:0030154,GO:0030331,GO:0030421,GO:0030879,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031399,GO:0031401,GO:0031536,GO:0031647,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032526,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033143,GO:0033144,GO:0033146,GO:0033147,GO:0033218,GO:0033365,GO:0033554,GO:0033599,GO:0033600,GO:0033993,GO:0034220,GO:0034399,GO:0034504,GO:0034613,GO:0035239,GO:0035257,GO:0035258,GO:0035295,GO:0035632,GO:0036293,GO:0036294,GO:0040008,GO:0040014,GO:0040018,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042695,GO:0042886,GO:0042981,GO:0043051,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043408,GO:0043410,GO:0043433,GO:0043467,GO:0044092,GO:0044093,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044703,GO:0045136,GO:0045137,GO:0045184,GO:0045787,GO:0045840,GO:0045892,GO:0045927,GO:0045931,GO:0045934,GO:0045937,GO:0046543,GO:0046907,GO:0047485,GO:0048232,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048608,GO:0048609,GO:0048638,GO:0048639,GO:0048729,GO:0048731,GO:0048732,GO:0048754,GO:0048856,GO:0048869,GO:0050678,GO:0050680,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050821,GO:0050896,GO:0051090,GO:0051091,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051169,GO:0051170,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051276,GO:0051427,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051785,GO:0055085,GO:0060255,GO:0060259,GO:0060429,GO:0060443,GO:0060444,GO:0060548,GO:0060562,GO:0060603,GO:0060688,GO:0060744,GO:0060749,GO:0060762,GO:0061138,GO:0061180,GO:0061377,GO:0061458,GO:0062012,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070372,GO:0070374,GO:0070482,GO:0070584,GO:0070588,GO:0070727,GO:0070838,GO:0070887,GO:0071229,GO:0071300,GO:0071310,GO:0071396,GO:0071453,GO:0071456,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072511,GO:0072594,GO:0080090,GO:0090068,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098805,GO:0098813,GO:1900542,GO:1901700,GO:1901701,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902531,GO:1902533,GO:1902679,GO:1902806,GO:1902808,GO:1903506,GO:1903507,GO:1903578,GO:1903998,GO:1905330,GO:2000026,GO:2000027,GO:2000112,GO:2000113,GO:2001141	-	ko:K17081	-	-	-	-	ko00000,ko03029,ko04147	-	-	-	Band_7
k59_283920_1	768671.ThimaDRAFT_0535	6.62e-68	221.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,1WXT8@135613|Chromatiales	135613|Chromatiales	S	PFAM Uncharacterised protein family UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_283920_2	1380394.JADL01000009_gene3208	7.64e-61	202.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,2JPKF@204441|Rhodospirillales	204441|Rhodospirillales	M	COG3264 Small-conductance mechanosensitive channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	DUF3772,MS_channel
k59_793176_2	1121374.KB891588_gene3320	4.09e-05	51.2	COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	pilus assembly protein PilW	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
k59_1225031_1	1232410.KI421413_gene828	7.83e-82	252.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RDM@68525|delta/epsilon subdivisions,2WMYM@28221|Deltaproteobacteria,43SX2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Bac_DnaA_C,Y1_Tnp
k59_1106936_1	266779.Meso_3326	7.19e-83	251.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,43HMP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
k59_88863_1	1121439.dsat_0641	3.29e-42	157.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43BK2@68525|delta/epsilon subdivisions,2X6XX@28221|Deltaproteobacteria,2MH87@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07712,ko:K07713	ko02020,map02020	M00497,M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,PAS_4,Response_reg,Sigma54_activat
k59_402003_1	29073.XP_008699634.1	1.66e-132	376.0	COG0097@1|root,KOG3255@2759|Eukaryota,39ZYK@33154|Opisthokonta,3BBJV@33208|Metazoa,3CSBG@33213|Bilateria,480A3@7711|Chordata,48X49@7742|Vertebrata,3J3Y0@40674|Mammalia,3EMCJ@33554|Carnivora	33208|Metazoa	J	ribosomal protein	RPL9	GO:0000184,GO:0000956,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009719,GO:0009892,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015934,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0042221,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0070727,GO:0070848,GO:0070887,GO:0070972,GO:0071310,GO:0071363,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990089,GO:1990090,GO:1990904	-	ko:K02940	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_9801_1	56780.SYN_01534	2.69e-55	194.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_558233_1	525897.Dbac_1891	1.61e-51	176.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,42QZK@68525|delta/epsilon subdivisions,2WMZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
k59_715488_1	545693.BMQ_2892	1.24e-05	47.0	COG0745@1|root,COG0745@2|Bacteria,1V18V@1239|Firmicutes,4HE9Y@91061|Bacilli,1ZMTB@1386|Bacillus	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_715488_2	525904.Tter_1031	1.58e-29	121.0	COG0642@1|root,COG2205@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
k59_479955_1	9541.XP_005544119.1	2.27e-160	451.0	COG0563@1|root,KOG3078@2759|Eukaryota,38FS5@33154|Opisthokonta,3B9GS@33208|Metazoa,3CY1W@33213|Bilateria,487E5@7711|Chordata,492RM@7742|Vertebrata,3J8CA@40674|Mammalia,35D5S@314146|Euarchontoglires,4M8QA@9443|Primates,35ZP8@314294|Cercopithecoidea	33208|Metazoa	F	Adenylate kinase 2	AK2	GO:0001889,GO:0002244,GO:0002376,GO:0002520,GO:0002521,GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005758,GO:0005829,GO:0005929,GO:0006091,GO:0006119,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006172,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009141,GO:0009144,GO:0009150,GO:0009151,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009199,GO:0009200,GO:0009205,GO:0009215,GO:0009259,GO:0009260,GO:0009262,GO:0009394,GO:0009719,GO:0009725,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010646,GO:0010648,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0019866,GO:0023051,GO:0023057,GO:0030097,GO:0030154,GO:0031090,GO:0031514,GO:0031966,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032501,GO:0032502,GO:0032878,GO:0034641,GO:0034654,GO:0036126,GO:0042221,GO:0042995,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044441,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0046031,GO:0046033,GO:0046034,GO:0046060,GO:0046083,GO:0046390,GO:0046483,GO:0046940,GO:0048513,GO:0048519,GO:0048523,GO:0048534,GO:0048583,GO:0048585,GO:0048731,GO:0048732,GO:0048856,GO:0048863,GO:0048869,GO:0050145,GO:0050789,GO:0050794,GO:0050896,GO:0055086,GO:0060218,GO:0060322,GO:0061008,GO:0065007,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0090036,GO:0090038,GO:0090407,GO:0097066,GO:0097223,GO:0097226,GO:0097729,GO:0120025,GO:0120038,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902531,GO:1902532,GO:2000114	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
k59_1225094_1	670307.HYPDE_35498	1.83e-107	328.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2TS0S@28211|Alphaproteobacteria,3N7Z1@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
k59_832492_1	1121918.ARWE01000001_gene3051	2.22e-71	226.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,42NEN@68525|delta/epsilon subdivisions,2WK9G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_1029693_1	1207063.P24_01680	7.89e-58	183.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2U72E@28211|Alphaproteobacteria,2JTAQ@204441|Rhodospirillales	204441|Rhodospirillales	S	sulfur oxidation protein (SoxY)	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
k59_1029693_2	1207063.P24_01675	6.57e-16	72.4	COG5501@1|root,COG5501@2|Bacteria,1N03V@1224|Proteobacteria,2TWQY@28211|Alphaproteobacteria,2JUCR@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulphur oxidation protein SoxZ	-	-	-	-	-	-	-	-	-	-	-	-	SoxZ
k59_675873_1	1453501.JELR01000002_gene116	3.13e-157	471.0	COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,464ZY@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
k59_715537_1	9606.ENSP00000358866	6.29e-116	369.0	COG5069@1|root,KOG0518@2759|Eukaryota,38DME@33154|Opisthokonta,3B9WI@33208|Metazoa,3CS2N@33213|Bilateria,480F7@7711|Chordata,49204@7742|Vertebrata,3JD57@40674|Mammalia,35H1Q@314146|Euarchontoglires,4ME6N@9443|Primates,4N2S4@9604|Hominidae	33208|Metazoa	Z	Filamin-type immunoglobulin domains	FLNA	GO:0000003,GO:0000226,GO:0000278,GO:0000280,GO:0000902,GO:0000904,GO:0001525,GO:0001568,GO:0001664,GO:0001775,GO:0001837,GO:0001944,GO:0001974,GO:0002009,GO:0002011,GO:0002064,GO:0002576,GO:0003006,GO:0003007,GO:0003674,GO:0003779,GO:0005080,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005730,GO:0005737,GO:0005794,GO:0005802,GO:0005829,GO:0005856,GO:0005884,GO:0005886,GO:0005903,GO:0005911,GO:0005938,GO:0006139,GO:0006351,GO:0006355,GO:0006356,GO:0006366,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006935,GO:0006937,GO:0006942,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007016,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007154,GO:0007165,GO:0007166,GO:0007186,GO:0007187,GO:0007188,GO:0007193,GO:0007195,GO:0007212,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007413,GO:0007417,GO:0007420,GO:0007507,GO:0007548,GO:0007596,GO:0007599,GO:0008016,GO:0008037,GO:0008038,GO:0008092,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008284,GO:0008406,GO:0008584,GO:0009058,GO:0009059,GO:0009299,GO:0009605,GO:0009611,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010638,GO:0010646,GO:0010647,GO:0010720,GO:0010721,GO:0010769,GO:0010770,GO:0010810,GO:0010811,GO:0010941,GO:0010959,GO:0010975,GO:0010977,GO:0012505,GO:0015459,GO:0015629,GO:0016020,GO:0016021,GO:0016043,GO:0016070,GO:0016071,GO:0016192,GO:0016247,GO:0016477,GO:0016479,GO:0016482,GO:0017016,GO:0017048,GO:0017160,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019900,GO:0019901,GO:0021535,GO:0021932,GO:0021943,GO:0022008,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030030,GO:0030031,GO:0030036,GO:0030054,GO:0030154,GO:0030155,GO:0030168,GO:0030182,GO:0030334,GO:0030335,GO:0030424,GO:0030425,GO:0030426,GO:0030427,GO:0030506,GO:0030855,GO:0030863,GO:0030902,GO:0031175,GO:0031224,GO:0031267,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031344,GO:0031345,GO:0031523,GO:0031532,GO:0031628,GO:0031647,GO:0031674,GO:0031852,GO:0031974,GO:0031981,GO:0031984,GO:0032231,GO:0032233,GO:0032432,GO:0032501,GO:0032502,GO:0032507,GO:0032774,GO:0032879,GO:0032940,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033267,GO:0034329,GO:0034330,GO:0034394,GO:0034613,GO:0034641,GO:0034645,GO:0034654,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0034987,GO:0034988,GO:0035239,GO:0035295,GO:0036477,GO:0040011,GO:0040012,GO:0040017,GO:0042060,GO:0042127,GO:0042176,GO:0042177,GO:0042221,GO:0042330,GO:0042383,GO:0042391,GO:0042789,GO:0042802,GO:0042803,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043034,GO:0043066,GO:0043067,GO:0043069,GO:0043113,GO:0043122,GO:0043123,GO:0043170,GO:0043198,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043266,GO:0043268,GO:0043269,GO:0043270,GO:0043292,GO:0043433,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044297,GO:0044319,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044427,GO:0044428,GO:0044430,GO:0044431,GO:0044444,GO:0044446,GO:0044448,GO:0044449,GO:0044463,GO:0044464,GO:0044782,GO:0044877,GO:0045022,GO:0045055,GO:0045137,GO:0045184,GO:0045185,GO:0045216,GO:0045595,GO:0045596,GO:0045597,GO:0045664,GO:0045665,GO:0045785,GO:0045892,GO:0045934,GO:0046332,GO:0046483,GO:0046546,GO:0046661,GO:0046903,GO:0046907,GO:0046983,GO:0048285,GO:0048365,GO:0048468,GO:0048471,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048608,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048729,GO:0048731,GO:0048762,GO:0048771,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050767,GO:0050768,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050817,GO:0050821,GO:0050878,GO:0050896,GO:0051015,GO:0051020,GO:0051049,GO:0051050,GO:0051090,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051179,GO:0051220,GO:0051225,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051270,GO:0051272,GO:0051493,GO:0051495,GO:0051641,GO:0051649,GO:0051651,GO:0051668,GO:0051674,GO:0051716,GO:0051764,GO:0051960,GO:0051961,GO:0051962,GO:0055117,GO:0060008,GO:0060009,GO:0060065,GO:0060255,GO:0060271,GO:0060284,GO:0060306,GO:0060322,GO:0060372,GO:0060429,GO:0060485,GO:0060548,GO:0061038,GO:0061458,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070727,GO:0070925,GO:0071526,GO:0071704,GO:0071840,GO:0071944,GO:0072358,GO:0072359,GO:0072657,GO:0072659,GO:0080090,GO:0086004,GO:0090257,GO:0090304,GO:0090307,GO:0090504,GO:0090505,GO:0097368,GO:0097435,GO:0097440,GO:0097447,GO:0097458,GO:0097485,GO:0097659,GO:0098772,GO:0098791,GO:0098862,GO:0098900,GO:0098901,GO:0098903,GO:0098910,GO:0098927,GO:0099080,GO:0099081,GO:0099106,GO:0099512,GO:0099513,GO:0099568,GO:0099623,GO:0106030,GO:0110053,GO:0120025,GO:0120031,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0140014,GO:0150034,GO:1900024,GO:1900026,GO:1901360,GO:1901362,GO:1901379,GO:1901381,GO:1901576,GO:1902396,GO:1902414,GO:1902531,GO:1902533,GO:1902679,GO:1902850,GO:1902903,GO:1902905,GO:1903047,GO:1903115,GO:1903506,GO:1903507,GO:1903522,GO:1903779,GO:1904062,GO:1904064,GO:1905000,GO:1905031,GO:1990778,GO:2000026,GO:2000112,GO:2000113,GO:2000145,GO:2000147,GO:2000177,GO:2000179,GO:2001044,GO:2001046,GO:2001141,GO:2001222,GO:2001224	-	ko:K04437	ko04010,ko04510,ko05132,ko05205,map04010,map04510,map05132,map05205	-	-	-	ko00000,ko00001,ko04147,ko04812	-	-	-	CH,Filamin
k59_166571_1	335543.Sfum_4014	1.16e-41	147.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2WJDQ@28221|Deltaproteobacteria,2MR11@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	TIGRFAM hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
k59_9850_1	83406.HDN1F_01240	1.59e-115	345.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1J4KM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
k59_1185495_2	1156919.QWC_25097	5.33e-22	97.4	COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,2VKXV@28216|Betaproteobacteria,3T30U@506|Alcaligenaceae	28216|Betaproteobacteria	G	xylanase chitin deacetylase	pgaB	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
k59_950155_1	243233.MCA2737	2.15e-13	68.2	2E600@1|root,330PC@2|Bacteria,1N9V9@1224|Proteobacteria,1SHAU@1236|Gammaproteobacteria,1XFBV@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_950155_2	1266914.ATUK01000011_gene2279	6.31e-07	51.6	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1WY2P@135613|Chromatiales	135613|Chromatiales	J	catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_950160_1	883078.HMPREF9695_04340	8.06e-27	109.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TTAY@28211|Alphaproteobacteria,3JSTW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	MA20_38000	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_950160_2	1353531.AZNX01000008_gene790	8.21e-24	99.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TUWV@28211|Alphaproteobacteria,4BC2C@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_558309_2	1121921.KB898706_gene3345	5.81e-21	89.4	COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,2PNR1@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Ribonuclease P	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k59_793260_1	1134474.O59_002021	3.83e-128	387.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1FGXV@10|Cellvibrio	1236|Gammaproteobacteria	O	Hsp90 protein	htpG	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
k59_1029796_1	1121405.dsmv_3002	1.04e-64	207.0	COG1737@1|root,COG1737@2|Bacteria,1PKMI@1224|Proteobacteria,42QMV@68525|delta/epsilon subdivisions,2WKNY@28221|Deltaproteobacteria,2MITX@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
k59_1067649_1	293826.Amet_1343	1.36e-30	122.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_558374_1	1163408.UU9_10412	9.17e-47	170.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1MXH9@1224|Proteobacteria,1RPQ6@1236|Gammaproteobacteria,1X52G@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156,LPG_synthase_TM
k59_675983_1	10036.XP_005073611.1	4.68e-120	359.0	COG0631@1|root,KOG0699@2759|Eukaryota,38CQG@33154|Opisthokonta,3B9BA@33208|Metazoa,3CY5N@33213|Bilateria,481MX@7711|Chordata,492M6@7742|Vertebrata,3J7K3@40674|Mammalia,35HGY@314146|Euarchontoglires,4Q2SF@9989|Rodentia	33208|Metazoa	T	protein serine/threonine phosphatase activity	PPM1G	GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007049,GO:0007050,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0022402,GO:0031974,GO:0031981,GO:0035970,GO:0036211,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045786,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051726,GO:0065007,GO:0070013,GO:0071704,GO:0140096,GO:1901564	3.1.3.16	ko:K17499	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C
k59_1029860_1	102129.Lepto7375DRAFT_7801	3.71e-56	189.0	COG3547@1|root,COG3547@2|Bacteria,1G077@1117|Cyanobacteria,1H97S@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_910717_1	716928.AJQT01000176_gene1361	1.55e-23	102.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2TUGE@28211|Alphaproteobacteria,4B7UY@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_482168_1	644282.Deba_1483	1.53e-19	85.9	29HYV@1|root,304VW@2|Bacteria,1RDPY@1224|Proteobacteria,42RXW@68525|delta/epsilon subdivisions,2WNTT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_482168_2	1232410.KI421416_gene2675	1.35e-37	129.0	COG0599@1|root,COG0599@2|Bacteria,1N2ZQ@1224|Proteobacteria,42VDR@68525|delta/epsilon subdivisions,2WRKS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
k59_756246_1	1123274.KB899407_gene284	1.74e-65	216.0	COG0696@1|root,COG0696@2|Bacteria,2J5QJ@203691|Spirochaetes	203691|Spirochaetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,iPGM_N
k59_1069614_2	686578.AFFX01000002_gene898	4.69e-108	318.0	COG0265@1|root,COG0265@2|Bacteria,1R40X@1224|Proteobacteria,1S2ZM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
k59_834699_1	1265505.ATUG01000002_gene2681	3.43e-88	269.0	COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,42SGW@68525|delta/epsilon subdivisions,2WPC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_1187661_1	1499967.BAYZ01000111_gene2946	4.85e-17	85.9	COG0642@1|root,COG2205@2|Bacteria,2NS4W@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_1228146_1	335543.Sfum_3299	7.52e-14	73.2	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2WJGT@28221|Deltaproteobacteria,2MQCY@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_11916_1	1144275.COCOR_04347	9.16e-44	155.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,42SUF@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	ornithine cyclodeaminase mu-crystallin	arcB	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
k59_1069636_1	1121405.dsmv_0639	5.87e-44	157.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
k59_503397_1	589865.DaAHT2_0484	1.48e-44	159.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria,2MMU3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_1090028_1	1042377.AFPJ01000020_gene2062	7.68e-104	317.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_1017567_1	382245.ASA_2732	6.42e-43	159.0	COG2267@1|root,COG2267@2|Bacteria,1QTZP@1224|Proteobacteria,1RPB9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
k59_463829_1	574087.Acear_0687	9.78e-37	135.0	COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,249PW@186801|Clostridia,3WBEN@53433|Halanaerobiales	186801|Clostridia	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
k59_71369_1	28152.DJ57_2482	9.67e-14	68.9	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1S5WH@1236|Gammaproteobacteria,41DNG@629|Yersinia	1236|Gammaproteobacteria	S	Belongs to the CinA family	ygaD	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
k59_71369_2	10228.TriadP18543	9.92e-22	95.1	COG1028@1|root,KOG1208@2759|Eukaryota,38CZD@33154|Opisthokonta,3BACQ@33208|Metazoa	33154|Opisthokonta	Q	NADP-retinol dehydrogenase activity	RDH13	GO:0001523,GO:0001654,GO:0001754,GO:0003407,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0007275,GO:0007399,GO:0007423,GO:0008106,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009628,GO:0009642,GO:0009644,GO:0009653,GO:0009887,GO:0009987,GO:0010817,GO:0010842,GO:0016020,GO:0016101,GO:0016491,GO:0016614,GO:0016616,GO:0019866,GO:0022008,GO:0030154,GO:0030182,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0034308,GO:0034754,GO:0042445,GO:0042461,GO:0042462,GO:0042572,GO:0043010,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046530,GO:0048468,GO:0048513,GO:0048592,GO:0048593,GO:0048646,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0052650,GO:0055114,GO:0060041,GO:0060042,GO:0065007,GO:0065008,GO:0071704,GO:0090596,GO:1901615	1.1.1.300,2.3.2.27	ko:K04506,ko:K11153,ko:K11161	ko00830,ko01100,ko04013,ko04115,ko04120,ko04310,map00830,map01100,map04013,map04115,map04120,map04310	-	R08379,R08383	RC00649	ko00000,ko00001,ko01000,ko04121	-	-	-	adh_short
k59_347044_1	9606.ENSP00000229270	5.27e-183	510.0	COG0149@1|root,KOG1643@2759|Eukaryota,38ETQ@33154|Opisthokonta,3B9YV@33208|Metazoa,3CW21@33213|Bilateria,487QC@7711|Chordata,491QM@7742|Vertebrata,3J30V@40674|Mammalia,35EPB@314146|Euarchontoglires,4M9ZK@9443|Primates,4N2DP@9604|Hominidae	33208|Metazoa	G	Belongs to the triosephosphate isomerase family	TPI1	GO:0000768,GO:0003008,GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006949,GO:0007275,GO:0007520,GO:0007525,GO:0007568,GO:0008150,GO:0008152,GO:0008340,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009987,GO:0010259,GO:0014902,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019674,GO:0019682,GO:0019693,GO:0019725,GO:0019751,GO:0019752,GO:0019899,GO:0030016,GO:0030017,GO:0030018,GO:0030154,GO:0031430,GO:0031625,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032787,GO:0033500,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042592,GO:0042593,GO:0042692,GO:0042802,GO:0042803,GO:0042866,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044389,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0045454,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0046983,GO:0048646,GO:0048856,GO:0048869,GO:0048878,GO:0050789,GO:0050794,GO:0050877,GO:0050896,GO:0051146,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061061,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0099080,GO:0099081,GO:0099512,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
k59_463851_1	1047013.AQSP01000123_gene1542	1.32e-19	92.4	COG2204@1|root,COG2204@2|Bacteria,2NP3X@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_32610_1	335543.Sfum_2649	4.89e-132	387.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2MQ96@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_738140_1	321332.CYB_0686	1.48e-95	301.0	COG1215@1|root,COG1215@2|Bacteria,1GBTF@1117|Cyanobacteria,1H3Z4@1129|Synechococcus	1117|Cyanobacteria	M	Glycosyl transferase, group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,T2SSE_N
k59_815187_1	1322246.BN4_12339	2.51e-52	184.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WKC0@28221|Deltaproteobacteria,2M7TX@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,HisKA,PAS_8,PAS_9,sCache_3_2
k59_113920_1	457421.CBFG_02129	1.52e-16	77.8	COG1802@1|root,COG1802@2|Bacteria,1V6ZD@1239|Firmicutes,24CBW@186801|Clostridia,26BEJ@186813|unclassified Clostridiales	186801|Clostridia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
k59_699225_1	717785.HYPMC_0932	1.54e-87	266.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,3N64F@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
k59_658965_1	566466.NOR53_3680	2.26e-35	128.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1J889@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
k59_268993_1	1287116.X734_00600	4.08e-20	84.0	COG3415@1|root,COG3415@2|Bacteria,1RJ69@1224|Proteobacteria,2UCXQ@28211|Alphaproteobacteria,43REE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	'Paired box' domain	-	-	-	ko:K07499	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_28,HTH_32,HTH_Tnp_IS630,HTH_Tnp_Tc3_2
k59_268993_2	698761.RTCIAT899_CH14505	3.72e-75	234.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,4BC2J@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase and inactivated	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
k59_738164_1	61853.ENSNLEP00000000400	2.31e-148	429.0	KOG0488@1|root,KOG0488@2759|Eukaryota,38BWG@33154|Opisthokonta,3BE75@33208|Metazoa,3CWG8@33213|Bilateria,482GY@7711|Chordata,490GU@7742|Vertebrata,3J4MH@40674|Mammalia,35AD3@314146|Euarchontoglires,4MIB4@9443|Primates	33208|Metazoa	K	Nucleophosmin (nucleolar phosphoprotein B23, numatrin)	NPM1	GO:0000054,GO:0000055,GO:0000056,GO:0000166,GO:0000226,GO:0000448,GO:0000460,GO:0000463,GO:0000466,GO:0000469,GO:0000470,GO:0000478,GO:0000479,GO:0000922,GO:0001047,GO:0001067,GO:0001558,GO:0001652,GO:0001666,GO:0001889,GO:0001932,GO:0001933,GO:0001934,GO:0002039,GO:0003008,GO:0003012,GO:0003300,GO:0003674,GO:0003676,GO:0003677,GO:0003712,GO:0003713,GO:0003723,GO:0004857,GO:0004860,GO:0005488,GO:0005515,GO:0005524,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005840,GO:0005856,GO:0006139,GO:0006259,GO:0006275,GO:0006281,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006336,GO:0006338,GO:0006351,GO:0006355,GO:0006357,GO:0006364,GO:0006396,GO:0006403,GO:0006405,GO:0006407,GO:0006417,GO:0006446,GO:0006469,GO:0006611,GO:0006725,GO:0006807,GO:0006810,GO:0006884,GO:0006886,GO:0006913,GO:0006950,GO:0006974,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007098,GO:0007154,GO:0007165,GO:0007275,GO:0007568,GO:0007569,GO:0008104,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008285,GO:0008289,GO:0008361,GO:0009058,GO:0009059,GO:0009303,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009719,GO:0009725,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009966,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010638,GO:0010639,GO:0010646,GO:0010656,GO:0010660,GO:0010662,GO:0010664,GO:0010665,GO:0010667,GO:0010824,GO:0010825,GO:0010826,GO:0010941,GO:0010948,GO:0014070,GO:0014896,GO:0014897,GO:0015031,GO:0015630,GO:0015833,GO:0015931,GO:0015934,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0016363,GO:0016604,GO:0016607,GO:0017076,GO:0018130,GO:0019207,GO:0019210,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019725,GO:0019843,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0022402,GO:0022607,GO:0022613,GO:0022618,GO:0023051,GO:0023052,GO:0030234,GO:0030554,GO:0030957,GO:0031023,GO:0031055,GO:0031099,GO:0031100,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031396,GO:0031398,GO:0031399,GO:0031400,GO:0031401,GO:0031497,GO:0031503,GO:0031616,GO:0031647,GO:0031974,GO:0031981,GO:0032069,GO:0032070,GO:0032071,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032535,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032870,GO:0032879,GO:0032880,GO:0032886,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033119,GO:0033554,GO:0033574,GO:0033613,GO:0033673,GO:0033674,GO:0033750,GO:0033993,GO:0034080,GO:0034248,GO:0034250,GO:0034399,GO:0034470,GO:0034508,GO:0034613,GO:0034622,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034660,GO:0034724,GO:0034728,GO:0035091,GO:0035639,GO:0036094,GO:0036293,GO:0036294,GO:0040008,GO:0042127,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0042325,GO:0042326,GO:0042327,GO:0042393,GO:0042592,GO:0042802,GO:0042803,GO:0042886,GO:0042981,GO:0043021,GO:0043023,GO:0043024,GO:0043044,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043331,GO:0043422,GO:0043484,GO:0043486,GO:0043487,GO:0043488,GO:0043516,GO:0043523,GO:0043524,GO:0043549,GO:0043933,GO:0044085,GO:0044087,GO:0044092,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044387,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044451,GO:0044452,GO:0044464,GO:0044877,GO:0045184,GO:0045727,GO:0045740,GO:0045786,GO:0045787,GO:0045859,GO:0045860,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046483,GO:0046599,GO:0046605,GO:0046606,GO:0046607,GO:0046907,GO:0046982,GO:0046983,GO:0047485,GO:0048024,GO:0048025,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050657,GO:0050658,GO:0050678,GO:0050680,GO:0050684,GO:0050686,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050896,GO:0051029,GO:0051052,GO:0051054,GO:0051059,GO:0051082,GO:0051090,GO:0051091,GO:0051092,GO:0051128,GO:0051129,GO:0051130,GO:0051168,GO:0051169,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051236,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051336,GO:0051338,GO:0051347,GO:0051348,GO:0051493,GO:0051494,GO:0051495,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0051716,GO:0051726,GO:0060255,GO:0060341,GO:0060548,GO:0060699,GO:0060700,GO:0060735,GO:0061008,GO:0061013,GO:0061641,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070482,GO:0070507,GO:0070727,GO:0070887,GO:0070925,GO:0071103,GO:0071166,GO:0071214,GO:0071310,GO:0071359,GO:0071394,GO:0071396,GO:0071407,GO:0071426,GO:0071428,GO:0071453,GO:0071456,GO:0071478,GO:0071482,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0071824,GO:0071826,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0090068,GO:0090304,GO:0090305,GO:0090329,GO:0090501,GO:0090502,GO:0097064,GO:0097159,GO:0097367,GO:0097421,GO:0097659,GO:0098772,GO:0098781,GO:0104004,GO:0140110,GO:1900180,GO:1900182,GO:1900262,GO:1900264,GO:1901214,GO:1901215,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901796,GO:1901981,GO:1901987,GO:1901989,GO:1902115,GO:1902531,GO:1902629,GO:1902680,GO:1902749,GO:1902751,GO:1903311,GO:1903312,GO:1903320,GO:1903322,GO:1903506,GO:1903508,GO:1903827,GO:1903829,GO:1904749,GO:1904751,GO:1990904,GO:2000112,GO:2000278,GO:2000573,GO:2001020,GO:2001141	-	ko:K11276	-	-	-	-	ko00000,ko03036	-	-	-	NPM1-C,Nucleoplasmin
k59_463890_1	999611.KI421504_gene854	1.6e-56	183.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,2814J@191028|Leisingera	28211|Alphaproteobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_1017619_2	396588.Tgr7_2744	1.08e-87	277.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales	135613|Chromatiales	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
k59_738190_1	566466.NOR53_1720	5.46e-33	120.0	2AGHX@1|root,316QI@2|Bacteria,1RI7I@1224|Proteobacteria,1S8W9@1236|Gammaproteobacteria,1J9ZI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_546164_1	99598.Cal7507_3676	7.55e-95	301.0	COG1452@1|root,COG1452@2|Bacteria,1G0TW@1117|Cyanobacteria,1HKTW@1161|Nostocales	1117|Cyanobacteria	M	PFAM Mannosyl oligosaccharide glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
k59_581792_1	998674.ATTE01000001_gene4226	9.81e-87	263.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,4607J@72273|Thiotrichales	72273|Thiotrichales	F	phosphoribosylaminoimidazole-succinocarboxamide synthase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
k59_113972_1	391626.OAN307_c45020	8.07e-32	127.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2TRXG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_113973_1	1100721.ALKO01000020_gene895	1.96e-52	178.0	COG2866@1|root,COG2866@2|Bacteria,1N6CX@1224|Proteobacteria,2VHWB@28216|Betaproteobacteria,4AAF4@80864|Comamonadaceae	28216|Betaproteobacteria	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2817
k59_815222_1	472759.Nhal_1189	3.61e-73	248.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1WX32@135613|Chromatiales	135613|Chromatiales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
k59_387570_1	342113.DM82_4547	3.61e-28	115.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,1K4RW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA polymerase	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
k59_1130308_1	1328313.DS2_15644	9.52e-11	70.1	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RSN6@1236|Gammaproteobacteria,4662Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1251246_1	1304872.JAGC01000003_gene3765	1.14e-08	56.2	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria,2M9HB@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_1130309_1	95619.PM1_0204975	2.07e-35	139.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1RS29@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14,6.4.1.6	ko:K01474,ko:K10854	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
k59_463942_1	1046724.KB889908_gene924	7.24e-13	73.9	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,4669Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
k59_895344_1	1380394.JADL01000012_gene1044	2.22e-73	232.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2TS4G@28211|Alphaproteobacteria,2JPEW@204441|Rhodospirillales	204441|Rhodospirillales	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
k59_659057_1	318167.Sfri_3579	2.19e-16	80.1	COG0823@1|root,COG0823@2|Bacteria,1QYUC@1224|Proteobacteria,1S70B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_463948_1	1121957.ATVL01000009_gene1038	2.17e-21	94.4	COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,47NAQ@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
k59_347144_1	391626.OAN307_c03800	9.9e-145	417.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k59_699321_1	439235.Dalk_1934	3.19e-111	331.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2MI0G@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
k59_347155_1	1282360.ABAC460_14340	3.42e-13	69.7	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2KIP9@204458|Caulobacterales	204458|Caulobacterales	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_347155_2	1267005.KB911261_gene2216	2.64e-33	118.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,3N6TQ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
k59_188905_1	1121406.JAEX01000003_gene1537	4.74e-59	203.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WJKV@28221|Deltaproteobacteria,2M7VM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K02482,ko:K10819	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9
k59_815272_1	1479237.JMLY01000001_gene3022	1.18e-64	211.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,46522@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_463960_1	717606.PaecuDRAFT_3780	3.15e-13	72.8	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HG4Y@91061|Bacilli,274IB@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_659074_1	207559.Dde_3406	1.85e-80	246.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NRE@68525|delta/epsilon subdivisions,2WM0E@28221|Deltaproteobacteria,2MAQ7@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_1090180_1	385682.AFSL01000040_gene227	3.03e-33	131.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	2.7.7.4	ko:K00957,ko:K07497	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_23,HTH_29,PAPS_reduct,rve,rve_3
k59_307941_1	52644.XP_010583838.1	2.13e-119	343.0	COG2147@1|root,KOG1696@2759|Eukaryota,38E34@33154|Opisthokonta,3BA8R@33208|Metazoa,3CUCZ@33213|Bilateria,481EY@7711|Chordata,48YQI@7742|Vertebrata,4GSRA@8782|Aves	33208|Metazoa	J	ribosomal protein L19	RPL19	GO:0000184,GO:0000956,GO:0001889,GO:0002181,GO:0002376,GO:0002520,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007275,GO:0007568,GO:0008104,GO:0008150,GO:0008152,GO:0008340,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010259,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015934,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030097,GO:0031099,GO:0031100,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0042788,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048513,GO:0048519,GO:0048534,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060255,GO:0061008,GO:0065007,GO:0070180,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:0097421,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904,GO:1990932	-	ko:K02885	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19e
k59_463975_1	1232410.KI421425_gene1552	1.4e-132	423.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42TDV@68525|delta/epsilon subdivisions,2WP7K@28221|Deltaproteobacteria,43UHJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
k59_895410_1	1167006.UWK_03288	1.11e-93	295.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2WKKT@28221|Deltaproteobacteria,2MPSR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_581881_1	335543.Sfum_2329	5.52e-102	301.0	COG2819@1|root,COG2819@2|Bacteria,1RAB4@1224|Proteobacteria,42WZ1@68525|delta/epsilon subdivisions,2WTDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
k59_1052910_1	1121939.L861_18145	7.62e-18	82.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1XIJ6@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
k59_1052910_2	1125718.HMPREF1318_0183	4.77e-36	133.0	COG0111@1|root,COG0111@2|Bacteria,2IC47@201174|Actinobacteria,4D7XW@85005|Actinomycetales	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_34723_1	1137799.GZ78_22295	4.4e-94	283.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1XH68@135619|Oceanospirillales	135619|Oceanospirillales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_817201_1	933262.AXAM01000004_gene2397	3.93e-91	285.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42QBN@68525|delta/epsilon subdivisions,2WK9R@28221|Deltaproteobacteria,2MJF9@213118|Desulfobacterales	1224|Proteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_660954_1	344747.PM8797T_10544	8.84e-56	189.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
k59_271126_2	511062.GU3_06960	1.31e-41	145.0	COG0780@1|root,COG2904@1|root,COG0780@2|Bacteria,COG2904@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,1Y3GJ@135624|Aeromonadales	135624|Aeromonadales	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
k59_817222_1	517418.Ctha_0617	2.93e-83	270.0	COG1138@1|root,COG1138@2|Bacteria,1FEUA@1090|Chlorobi	1090|Chlorobi	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
k59_271135_1	1265505.ATUG01000001_gene3573	4.15e-65	216.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2MIU8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_151797_1	1312959.KI914647_gene194	3.26e-32	123.0	COG3677@1|root,COG3677@2|Bacteria,2IF2C@201174|Actinobacteria	201174|Actinobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_779527_1	349124.Hhal_1696	1.62e-73	239.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1WX1G@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
k59_740191_1	631454.N177_4000	1.32e-119	368.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2TTPX@28211|Alphaproteobacteria,1JQMG@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	fdhF	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_271159_2	1521187.JPIM01000050_gene3444	5.3e-06	52.4	COG1555@1|root,COG1555@2|Bacteria,2G771@200795|Chloroflexi,377EV@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM competence protein ComEA helix-hairpin-helix repeat protein	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
k59_548300_1	595537.Varpa_4952	1.2e-90	282.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VJHP@28216|Betaproteobacteria,4AD6J@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
k59_935258_1	1123023.JIAI01000002_gene4974	1.11e-43	152.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
k59_935258_2	591158.SSMG_04683	1.53e-06	49.3	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
k59_1171941_1	1267005.KB911266_gene1251	1.91e-126	367.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2TTXT@28211|Alphaproteobacteria,3N82Q@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_34803_1	404589.Anae109_4061	1.28e-92	293.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,42P3R@68525|delta/epsilon subdivisions,2X349@28221|Deltaproteobacteria,2YU6W@29|Myxococcales	28221|Deltaproteobacteria	H	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
k59_34809_1	1121396.KB893133_gene658	2.42e-91	276.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42NUE@68525|delta/epsilon subdivisions,2WJYH@28221|Deltaproteobacteria,2MI0A@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_190898_1	511062.GU3_10905	4.57e-18	90.1	COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,1RMXK@1236|Gammaproteobacteria,1Y54G@135624|Aeromonadales	135624|Aeromonadales	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K05776	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	ABC_tran
k59_465911_1	765420.OSCT_0363	1.97e-84	264.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi,374Y9@32061|Chloroflexia	32061|Chloroflexia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_73462_1	879212.DespoDRAFT_02406	3.15e-56	196.0	COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	OmpA,VWA,VWA_2
k59_1171981_1	118797.XP_007453473.1	3.47e-83	254.0	KOG2190@1|root,KOG2190@2759|Eukaryota,38G1X@33154|Opisthokonta,3BX98@33208|Metazoa,3CY62@33213|Bilateria,480AI@7711|Chordata,49KZT@7742|Vertebrata,3J68M@40674|Mammalia,4J785@91561|Cetartiodactyla	33208|Metazoa	A	KH domain	PCBP1	GO:0000375,GO:0000377,GO:0000398,GO:0000981,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003700,GO:0003723,GO:0003729,GO:0003730,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008494,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016032,GO:0016070,GO:0016071,GO:0016604,GO:0016607,GO:0019058,GO:0019079,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0034641,GO:0035770,GO:0036464,GO:0039694,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045182,GO:0045727,GO:0045893,GO:0045935,GO:0045944,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0098847,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990904,GO:2000112,GO:2001141	-	ko:K12889	ko03040,ko04216,map03040,map04216	-	-	-	ko00000,ko00001,ko03019,ko03041	-	-	-	KH_1
k59_34879_1	1395571.TMS3_0100965	1.33e-37	129.0	COG3070@1|root,COG3070@2|Bacteria,1NAYG@1224|Proteobacteria,1SDXZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
k59_34879_2	414684.RC1_2452	2.78e-11	65.9	COG3258@1|root,COG3258@2|Bacteria,1MZJW@1224|Proteobacteria,2UCKE@28211|Alphaproteobacteria,2JX7A@204441|Rhodospirillales	204441|Rhodospirillales	C	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
k59_976665_1	483219.LILAB_19540	1.13e-27	118.0	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,42PS5@68525|delta/epsilon subdivisions,2X77E@28221|Deltaproteobacteria,2YYG0@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
k59_897502_1	1122134.KB893651_gene1986	4.51e-97	295.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1XIJG@135619|Oceanospirillales	135619|Oceanospirillales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
k59_779678_1	926692.AZYG01000085_gene856	2.37e-70	226.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,249HN@186801|Clostridia,3WA8E@53433|Halanaerobiales	186801|Clostridia	L	Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_1132473_1	1121396.KB893100_gene4319	2.19e-86	285.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
k59_151941_1	1265505.ATUG01000002_gene1455	9.82e-152	443.0	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,42QHA@68525|delta/epsilon subdivisions,2WMFT@28221|Deltaproteobacteria,2MHYN@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_1092309_1	556268.OFAG_01329	3.95e-70	216.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,472UP@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
k59_1092309_2	59538.XP_005979544.1	4.04e-19	85.9	COG0065@1|root,KOG0454@2759|Eukaryota,39N7J@33154|Opisthokonta,3BN86@33208|Metazoa,3DDPN@33213|Bilateria,48SQ4@7711|Chordata,49P7V@7742|Vertebrata,3JQF1@40674|Mammalia,4JCCF@91561|Cetartiodactyla	33208|Metazoa	E	3-isopropylmalate dehydratase-like	-	-	-	-	-	-	-	-	-	-	-	-	Aconitase,Aconitase_C
k59_843657_1	667014.Thein_0214	8.55e-43	146.0	COG0779@1|root,COG0779@2|Bacteria,2GH5M@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
k59_843659_1	1415780.JPOG01000001_gene3152	6.23e-149	432.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,1RNDU@1236|Gammaproteobacteria,1XABV@135614|Xanthomonadales	135614|Xanthomonadales	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
k59_218309_1	497964.CfE428DRAFT_2658	1.02e-58	192.0	COG0714@1|root,COG0714@2|Bacteria,46S8X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1005109_1	765912.Thimo_2267	1.32e-27	103.0	COG0636@1|root,COG0636@2|Bacteria,1N5D3@1224|Proteobacteria,1SBV1@1236|Gammaproteobacteria,1WZ48@135613|Chromatiales	135613|Chromatiales	U	Belongs to the V-ATPase proteolipid subunit family	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
k59_765115_1	1232683.ADIMK_0681	6.05e-46	162.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,4641I@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	Glutaredoxin,PALP
k59_765115_2	408672.NBCG_01187	1.98e-14	70.5	COG2030@1|root,COG2030@2|Bacteria,2IJVW@201174|Actinobacteria,4DUKT@85009|Propionibacteriales	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k59_374048_1	589865.DaAHT2_0825	9.13e-28	113.0	COG1614@1|root,COG1614@2|Bacteria,1MVI5@1224|Proteobacteria,42N9A@68525|delta/epsilon subdivisions,2WK4H@28221|Deltaproteobacteria,2MIRV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit	-	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
k59_374048_2	335543.Sfum_2566	6.42e-24	100.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MQ8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_334336_1	335543.Sfum_1970	6.74e-96	286.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,42MVW@68525|delta/epsilon subdivisions,2WKKC@28221|Deltaproteobacteria,2MQGV@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Oxidoreductase NAD-binding domain	hdrF	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
k59_491302_1	314285.KT71_12215	1.49e-20	97.8	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_3,Plug,TonB_dep_Rec
k59_1196646_1	61622.XP_010352886.1	3.12e-287	811.0	KOG0123@1|root,KOG0123@2759|Eukaryota,3AAPF@33154|Opisthokonta,3BK6B@33208|Metazoa,3CX0S@33213|Bilateria,482M1@7711|Chordata,48V4N@7742|Vertebrata,3JAYT@40674|Mammalia,359VV@314146|Euarchontoglires,4MFNY@9443|Primates,3697Q@314294|Cercopithecoidea	33208|Metazoa	A	Nucleolin	NCL	GO:0000003,GO:0001525,GO:0001568,GO:0001650,GO:0001651,GO:0001817,GO:0001819,GO:0001889,GO:0001944,GO:0002237,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0003729,GO:0005102,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005938,GO:0006355,GO:0006356,GO:0006357,GO:0006417,GO:0006810,GO:0006897,GO:0007275,GO:0007276,GO:0007283,GO:0008022,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009719,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009986,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010941,GO:0016192,GO:0017148,GO:0019219,GO:0019222,GO:0019843,GO:0019899,GO:0019953,GO:0022414,GO:0031099,GO:0031100,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032675,GO:0032680,GO:0032755,GO:0032760,GO:0032879,GO:0032880,GO:0032991,GO:0033993,GO:0034097,GO:0034248,GO:0034249,GO:0035239,GO:0035295,GO:0035368,GO:0035770,GO:0036464,GO:0042134,GO:0042162,GO:0042221,GO:0042393,GO:0042802,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043236,GO:0043565,GO:0044087,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044452,GO:0044464,GO:0044547,GO:0044703,GO:0045893,GO:0045935,GO:0045943,GO:0045944,GO:0046872,GO:0048027,GO:0048232,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050840,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0060548,GO:0061008,GO:0065007,GO:0070013,GO:0070201,GO:0070848,GO:0070849,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071345,GO:0071363,GO:0071364,GO:0071396,GO:0071495,GO:0071944,GO:0072358,GO:0072359,GO:0080090,GO:0090069,GO:0090087,GO:0097159,GO:0097421,GO:0098657,GO:0099568,GO:1901363,GO:1901700,GO:1901701,GO:1901836,GO:1901838,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:1903532,GO:1903555,GO:1903557,GO:1904951,GO:1990631,GO:1990823,GO:1990830,GO:1990904,GO:2000112,GO:2000113,GO:2000232,GO:2000778,GO:2001141	-	ko:K11294	ko05130,map05130	-	-	-	ko00000,ko00001,ko03009,ko03036	-	-	-	RRM_1,Treacle
k59_374067_2	981384.AEYW01000014_gene162	1.3e-15	74.7	2E46N@1|root,32Z2M@2|Bacteria,1N6SH@1224|Proteobacteria,2UHDJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_843690_1	1121456.ATVA01000011_gene1507	1.58e-43	152.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WJ0U@28221|Deltaproteobacteria,2M88V@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
k59_843690_2	589865.DaAHT2_1355	8.57e-38	134.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WIY9@28221|Deltaproteobacteria,2MHVV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
k59_100357_1	318167.Sfri_0290	3.27e-78	258.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,2QAFC@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_1157129_1	1174684.EBMC1_01280	1.3e-89	277.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,2K05E@204457|Sphingomonadales	204457|Sphingomonadales	KL	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
k59_1157129_2	331869.BAL199_00070	1.92e-12	64.3	2E8HV@1|root,332VX@2|Bacteria,1NB2K@1224|Proteobacteria,2UFU2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1078122_1	1121405.dsmv_2827	3.52e-60	198.0	COG1522@1|root,COG1522@2|Bacteria,1R534@1224|Proteobacteria,42N0K@68525|delta/epsilon subdivisions,2WKX8@28221|Deltaproteobacteria,2MIJ2@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,ParBc
k59_138101_1	880072.Desac_0138	1.36e-65	211.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2MQBD@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_1005173_1	1500893.JQNB01000001_gene488	4.27e-109	328.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1X3US@135614|Xanthomonadales	135614|Xanthomonadales	NU	Pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_218396_1	314345.SPV1_05919	7.62e-100	300.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria	1224|Proteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSbBS512_1146.SbBS512_E3351	PGK
k59_726555_1	1047013.AQSP01000076_gene1475	1.12e-43	149.0	COG0190@1|root,COG0190@2|Bacteria,2NNY1@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_1042636_1	279238.Saro_2627	3.42e-37	143.0	COG0591@1|root,COG4251@1|root,COG0591@2|Bacteria,COG4251@2|Bacteria,1QTSW@1224|Proteobacteria,2TW0C@28211|Alphaproteobacteria,2K0PA@204457|Sphingomonadales	204457|Sphingomonadales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
k59_803671_1	439235.Dalk_1508	8.98e-87	264.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,42NJR@68525|delta/epsilon subdivisions,2WKAM@28221|Deltaproteobacteria,2MJHK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
k59_531749_1	1122603.ATVI01000007_gene1437	8.43e-09	60.1	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,1X6XU@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane protein, required for colicin V production	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
k59_419967_1	584708.Apau_1863	2.68e-17	83.2	COG4907@1|root,COG4907@2|Bacteria,3TA8F@508458|Synergistetes	508458|Synergistetes	S	membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
k59_419967_2	1114922.CIFAM_12_00280	7.01e-18	80.1	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
k59_419968_1	933262.AXAM01000040_gene1226	7.63e-68	229.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2MI1W@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
k59_1080414_1	1121439.dsat_0719	1.78e-11	69.7	COG4191@1|root,COG4191@2|Bacteria,1R6YZ@1224|Proteobacteria,42MXA@68525|delta/epsilon subdivisions,2WKQY@28221|Deltaproteobacteria,2M7WX@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS_4
k59_419987_1	935863.AWZR01000007_gene128	4.16e-32	116.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1X6EJ@135614|Xanthomonadales	135614|Xanthomonadales	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
k59_419987_2	1121015.N789_09260	7.14e-70	225.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1X453@135614|Xanthomonadales	135614|Xanthomonadales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_1242012_1	2340.JV46_26680	3.69e-107	319.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,1RNTJ@1236|Gammaproteobacteria,1JB7M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
k59_611467_1	765912.Thimo_2320	2.21e-78	248.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1WW8I@135613|Chromatiales	135613|Chromatiales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
k59_571745_2	1121405.dsmv_3642	9.35e-78	234.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2MJJG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
k59_180039_1	454957.IA64_03705	8.21e-76	247.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1X3IX@135614|Xanthomonadales	135614|Xanthomonadales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_336857_1	384765.SIAM614_29211	0.000212	43.5	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2U4DX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_454159_1	991905.SL003B_3550	1.4e-74	239.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,4BPZN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	fcS	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1159555_1	555079.Toce_1930	1.66e-59	201.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,42FCP@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilB	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
k59_571780_1	1163408.UU9_10779	1.09e-78	248.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1X55Q@135614|Xanthomonadales	135614|Xanthomonadales	EH	component I	pabB	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
k59_1198995_1	1282876.BAOK01000002_gene46	8.32e-49	164.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,4BQ29@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
k59_1198995_2	1304876.AZVC01000016_gene280	2.19e-08	54.7	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,1W859@1268|Micrococcaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA8	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_611506_1	1234364.AMSF01000086_gene2826	3.58e-08	53.5	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,1SA30@1236|Gammaproteobacteria,1X3FW@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_964119_1	1173029.JH980292_gene1123	1.48e-31	126.0	COG0318@1|root,COG0318@2|Bacteria,1G4CE@1117|Cyanobacteria,1H8QS@1150|Oscillatoriales	1117|Cyanobacteria	IQ	Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C,PP-binding
k59_728703_1	1229204.AMYY01000040_gene1707	4.75e-26	108.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2TSJK@28211|Alphaproteobacteria,4BPZP@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
k59_611529_1	420324.KI911992_gene7685	1.84e-10	63.5	COG1752@1|root,COG1752@2|Bacteria,1NT1Q@1224|Proteobacteria,2TRM3@28211|Alphaproteobacteria,1JQQY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Patatin	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
k59_923603_1	1396141.BATP01000047_gene3900	1.28e-55	194.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,46TPA@74201|Verrucomicrobia,2IU1D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
k59_611535_1	990285.RGCCGE502_04042	4.87e-13	71.2	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TTXX@28211|Alphaproteobacteria,4BC6Z@82115|Rhizobiaceae	28211|Alphaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030,ko:K10001	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	SBP_bac_3
k59_1008261_1	27679.XP_003925742.1	2.07e-66	217.0	COG0459@1|root,KOG0356@2759|Eukaryota,38BJH@33154|Opisthokonta,3BE0G@33208|Metazoa,3CX9K@33213|Bilateria,4804Y@7711|Chordata,49073@7742|Vertebrata,3JDS5@40674|Mammalia,35DDH@314146|Euarchontoglires,4MF6R@9443|Primates	33208|Metazoa	O	protein refolding	HSPD1	GO:0000302,GO:0001530,GO:0001666,GO:0001775,GO:0001816,GO:0001817,GO:0001819,GO:0002020,GO:0002039,GO:0002119,GO:0002164,GO:0002200,GO:0002204,GO:0002208,GO:0002218,GO:0002221,GO:0002224,GO:0002237,GO:0002250,GO:0002252,GO:0002253,GO:0002263,GO:0002285,GO:0002312,GO:0002366,GO:0002367,GO:0002368,GO:0002376,GO:0002377,GO:0002381,GO:0002440,GO:0002443,GO:0002449,GO:0002460,GO:0002520,GO:0002562,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0002697,GO:0002699,GO:0002703,GO:0002705,GO:0002706,GO:0002708,GO:0002709,GO:0002711,GO:0002755,GO:0002757,GO:0002758,GO:0002764,GO:0002791,GO:0002793,GO:0002819,GO:0002821,GO:0002822,GO:0002824,GO:0002831,GO:0002833,GO:0002834,GO:0002836,GO:0002837,GO:0002839,GO:0002840,GO:0002842,GO:0002931,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003697,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005768,GO:0005769,GO:0005777,GO:0005782,GO:0005783,GO:0005791,GO:0005794,GO:0005829,GO:0005886,GO:0005905,GO:0006139,GO:0006259,GO:0006310,GO:0006355,GO:0006357,GO:0006457,GO:0006458,GO:0006605,GO:0006626,GO:0006725,GO:0006807,GO:0006810,GO:0006839,GO:0006886,GO:0006915,GO:0006919,GO:0006950,GO:0006955,GO:0006979,GO:0006986,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007584,GO:0008035,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008289,GO:0008637,GO:0009266,GO:0009408,GO:0009409,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009719,GO:0009725,GO:0009790,GO:0009791,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009986,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010604,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0012505,GO:0014070,GO:0014074,GO:0014823,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016064,GO:0016444,GO:0016445,GO:0016447,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017038,GO:0017046,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0019724,GO:0019866,GO:0019899,GO:0022407,GO:0022409,GO:0022607,GO:0023052,GO:0030061,GO:0030135,GO:0030141,GO:0030155,GO:0030162,GO:0031090,GO:0031224,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031347,GO:0031349,GO:0031410,GO:0031625,GO:0031647,GO:0031667,GO:0031907,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031982,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032479,GO:0032481,GO:0032496,GO:0032501,GO:0032502,GO:0032647,GO:0032649,GO:0032653,GO:0032655,GO:0032675,GO:0032680,GO:0032727,GO:0032729,GO:0032733,GO:0032735,GO:0032755,GO:0032760,GO:0032879,GO:0032880,GO:0032943,GO:0032991,GO:0033036,GO:0033198,GO:0033218,GO:0033365,GO:0033554,GO:0033993,GO:0034185,GO:0034186,GO:0034514,GO:0034605,GO:0034613,GO:0034620,GO:0034622,GO:0034641,GO:0035966,GO:0035967,GO:0036293,GO:0036477,GO:0042026,GO:0042100,GO:0042110,GO:0042113,GO:0042220,GO:0042221,GO:0042277,GO:0042493,GO:0042542,GO:0042562,GO:0042579,GO:0042588,GO:0042886,GO:0042981,GO:0043025,GO:0043030,GO:0043032,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043170,GO:0043207,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0043231,GO:0043233,GO:0043235,GO:0043279,GO:0043280,GO:0043281,GO:0043523,GO:0043524,GO:0043559,GO:0043565,GO:0043627,GO:0043933,GO:0044085,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044297,GO:0044389,GO:0044403,GO:0044419,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044743,GO:0044877,GO:0045041,GO:0045088,GO:0045089,GO:0045121,GO:0045184,GO:0045190,GO:0045321,GO:0045785,GO:0045862,GO:0046483,GO:0046649,GO:0046651,GO:0046677,GO:0046683,GO:0046696,GO:0046907,GO:0046982,GO:0046983,GO:0048291,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050727,GO:0050729,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051087,GO:0051131,GO:0051171,GO:0051173,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051249,GO:0051251,GO:0051252,GO:0051336,GO:0051345,GO:0051384,GO:0051604,GO:0051641,GO:0051649,GO:0051702,GO:0051704,GO:0051707,GO:0051716,GO:0052547,GO:0052548,GO:0055085,GO:0060255,GO:0060359,GO:0060548,GO:0061077,GO:0065002,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070062,GO:0070201,GO:0070482,GO:0070585,GO:0070661,GO:0070727,GO:0070887,GO:0071310,GO:0071702,GO:0071704,GO:0071705,GO:0071806,GO:0071813,GO:0071814,GO:0071840,GO:0071865,GO:0071866,GO:0071944,GO:0072347,GO:0072594,GO:0072655,GO:0080090,GO:0080134,GO:0090087,GO:0090304,GO:0097159,GO:0097367,GO:0097458,GO:0097708,GO:0098589,GO:0098796,GO:0098805,GO:0098857,GO:0099503,GO:0140030,GO:1901214,GO:1901215,GO:1901360,GO:1901363,GO:1901564,GO:1901698,GO:1901700,GO:1903037,GO:1903039,GO:1903426,GO:1903427,GO:1903506,GO:1903530,GO:1903532,GO:1903555,GO:1903557,GO:1903561,GO:1904467,GO:1904469,GO:1904951,GO:1990542,GO:1990837,GO:2000112,GO:2000116,GO:2000377,GO:2000378,GO:2000778,GO:2001056,GO:2001141	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_885496_1	665571.STHERM_c02830	1.63e-89	276.0	COG0174@1|root,COG0174@2|Bacteria,2J6JS@203691|Spirochaetes	203691|Spirochaetes	E	PFAM Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_336934_1	933262.AXAM01000002_gene561	1.72e-60	195.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2MI66@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_846196_1	187272.Mlg_2774	5.25e-35	135.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1WVYV@135613|Chromatiales	135613|Chromatiales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
k59_846196_2	247633.GP2143_12566	1.53e-13	73.2	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1J4R4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
k59_649776_1	671143.DAMO_2373	5.61e-67	216.0	COG1012@1|root,COG1012@2|Bacteria,2NNW6@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_180148_1	880072.Desac_1431	3.94e-52	166.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,42RE3@68525|delta/epsilon subdivisions,2WPD5@28221|Deltaproteobacteria,2MRU2@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
k59_767682_1	877421.AUJT01000002_gene1156	6.04e-12	70.5	28IN0@1|root,2Z8NG@2|Bacteria,1VKBU@1239|Firmicutes,24WSS@186801|Clostridia,27J39@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Glycosyltransferase family 10 (fucosyltransferase) C-term	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_10
k59_298419_1	926549.KI421517_gene3817	4.7e-84	270.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,47MEE@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
k59_885548_1	933262.AXAM01000056_gene3171	2.71e-63	203.0	2ADFT@1|root,3135W@2|Bacteria,1MY8W@1224|Proteobacteria,42SW3@68525|delta/epsilon subdivisions,2WPYE@28221|Deltaproteobacteria,2MK86@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1199108_1	1121405.dsmv_3102	4.81e-20	95.9	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2MHSK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_221717_1	1347086.CCBA010000019_gene1133	7.54e-52	176.0	COG3239@1|root,COG3239@2|Bacteria,1TP3B@1239|Firmicutes,4H9TS@91061|Bacilli,1ZAYJ@1386|Bacillus	91061|Bacilli	I	fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
k59_767692_1	1384054.N790_11500	2.15e-26	109.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,1S8IP@1236|Gammaproteobacteria,1X7A0@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_923688_1	551275.KB899544_gene916	4.17e-68	228.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2TWVC@28211|Alphaproteobacteria,440R8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_649827_1	61622.XP_010372165.1	5.63e-106	333.0	KOG3637@1|root,KOG3637@2759|Eukaryota,38CFX@33154|Opisthokonta,3B96W@33208|Metazoa,3CUDX@33213|Bilateria,486UU@7711|Chordata,495EQ@7742|Vertebrata,3JB22@40674|Mammalia,35GU8@314146|Euarchontoglires,4MASQ@9443|Primates,35XMI@314294|Cercopithecoidea	33208|Metazoa	W	Integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	ITGA5	GO:0000003,GO:0000902,GO:0000904,GO:0001525,GO:0001568,GO:0001667,GO:0001704,GO:0001706,GO:0001708,GO:0001726,GO:0001894,GO:0001932,GO:0001934,GO:0001944,GO:0002009,GO:0002011,GO:0002064,GO:0002065,GO:0002066,GO:0002119,GO:0002164,GO:0002165,GO:0002376,GO:0002520,GO:0003006,GO:0003008,GO:0003674,GO:0004888,GO:0005102,GO:0005126,GO:0005154,GO:0005161,GO:0005172,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005794,GO:0005886,GO:0005887,GO:0005912,GO:0005924,GO:0005925,GO:0006928,GO:0006935,GO:0006950,GO:0006996,GO:0007010,GO:0007044,GO:0007154,GO:0007155,GO:0007157,GO:0007159,GO:0007160,GO:0007165,GO:0007166,GO:0007229,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007369,GO:0007399,GO:0007409,GO:0007411,GO:0007414,GO:0007417,GO:0007419,GO:0007424,GO:0007426,GO:0007427,GO:0007431,GO:0007435,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007492,GO:0007494,GO:0007517,GO:0007552,GO:0007560,GO:0007600,GO:0007606,GO:0007608,GO:0007610,GO:0007611,GO:0007613,GO:0008037,GO:0008038,GO:0008104,GO:0008150,GO:0008305,GO:0008587,GO:0009605,GO:0009611,GO:0009653,GO:0009790,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009893,GO:0009897,GO:0009925,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010562,GO:0010604,GO:0010631,GO:0010646,GO:0010647,GO:0010648,GO:0010669,GO:0010810,GO:0010811,GO:0010927,GO:0010941,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016203,GO:0016323,GO:0016477,GO:0019220,GO:0019222,GO:0019953,GO:0021551,GO:0022008,GO:0022412,GO:0022414,GO:0022603,GO:0022607,GO:0022610,GO:0022612,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030016,GO:0030017,GO:0030029,GO:0030030,GO:0030036,GO:0030054,GO:0030055,GO:0030097,GO:0030100,GO:0030154,GO:0030155,GO:0030182,GO:0030198,GO:0030239,GO:0030334,GO:0030335,GO:0030707,GO:0030855,GO:0030947,GO:0030949,GO:0031032,GO:0031175,GO:0031224,GO:0031226,GO:0031252,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031410,GO:0031430,GO:0031589,GO:0031672,GO:0031982,GO:0032231,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032956,GO:0032970,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033043,GO:0033627,GO:0033631,GO:0034113,GO:0034329,GO:0034330,GO:0034446,GO:0035099,GO:0035107,GO:0035114,GO:0035120,GO:0035152,GO:0035160,GO:0035162,GO:0035220,GO:0035239,GO:0035272,GO:0035295,GO:0035313,GO:0035987,GO:0038023,GO:0040011,GO:0040012,GO:0040017,GO:0040025,GO:0040028,GO:0042058,GO:0042059,GO:0042060,GO:0042221,GO:0042325,GO:0042327,GO:0042330,GO:0042383,GO:0042592,GO:0042692,GO:0042981,GO:0042995,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043184,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043235,GO:0043292,GO:0044085,GO:0044087,GO:0044319,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044449,GO:0044459,GO:0044464,GO:0044703,GO:0044877,GO:0045165,GO:0045178,GO:0045185,GO:0045202,GO:0045214,GO:0045765,GO:0045766,GO:0045785,GO:0045807,GO:0045937,GO:0046982,GO:0046983,GO:0048468,GO:0048477,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048563,GO:0048565,GO:0048568,GO:0048569,GO:0048580,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0048871,GO:0050730,GO:0050731,GO:0050764,GO:0050766,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050877,GO:0050890,GO:0050896,GO:0050900,GO:0051049,GO:0051050,GO:0051094,GO:0051128,GO:0051130,GO:0051146,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051235,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051270,GO:0051272,GO:0051492,GO:0051493,GO:0051674,GO:0051704,GO:0051716,GO:0055001,GO:0055002,GO:0055120,GO:0055123,GO:0060089,GO:0060099,GO:0060100,GO:0060249,GO:0060255,GO:0060429,GO:0060538,GO:0060541,GO:0060548,GO:0060562,GO:0060627,GO:0061061,GO:0061062,GO:0061564,GO:0065007,GO:0065008,GO:0070161,GO:0070851,GO:0070925,GO:0071062,GO:0071840,GO:0071944,GO:0072325,GO:0072327,GO:0072358,GO:0072359,GO:0080090,GO:0090130,GO:0090132,GO:0090287,GO:0090504,GO:0090505,GO:0097435,GO:0097485,GO:0097708,GO:0098552,GO:0098590,GO:0098609,GO:0098636,GO:0098742,GO:0098796,GO:0098797,GO:0098802,GO:0099080,GO:0099081,GO:0099512,GO:0110020,GO:0110053,GO:0120025,GO:0120036,GO:0120039,GO:1901074,GO:1901076,GO:1901184,GO:1901185,GO:1901342,GO:1902903,GO:1903670,GO:1903672,GO:1904018,GO:1905153,GO:1905155,GO:2000026,GO:2000145,GO:2000147,GO:2000209,GO:2000425,GO:2000427,GO:2000811	-	ko:K06484,ko:K06487,ko:K06584	ko04145,ko04151,ko04510,ko04512,ko04514,ko04640,ko04810,ko04919,ko05100,ko05131,ko05133,ko05165,ko05200,ko05205,ko05206,ko05222,ko05410,ko05412,ko05414,ko05418,map04145,map04151,map04510,map04512,map04514,map04640,map04810,map04919,map05100,map05131,map05133,map05165,map05200,map05205,map05206,map05222,map05410,map05412,map05414,map05418	-	-	-	ko00000,ko00001,ko04090,ko04131,ko04147,ko04516	-	-	-	FG-GAP,Integrin_alpha,Integrin_alpha2
k59_61872_1	880072.Desac_0096	2.83e-35	139.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_8,PAS_9,Response_reg,SBP_bac_3
k59_885571_1	715451.ambt_20910	7.96e-37	142.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D1@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_571917_1	2340.JV46_05520	2.34e-122	360.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,1RQ01@1236|Gammaproteobacteria,1J4TK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	norB	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
k59_923693_1	1121413.JMKT01000011_gene2432	5.08e-111	329.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2M88A@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_805961_1	1247726.MIM_c37210	1.64e-08	60.1	COG1028@1|root,COG1028@2|Bacteria,1MXQR@1224|Proteobacteria,2VIQY@28216|Betaproteobacteria,3T5S5@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_1242220_1	9940.ENSOARP00000009687	1.86e-124	365.0	KOG2754@1|root,KOG2754@2759|Eukaryota,38ERA@33154|Opisthokonta,3BD6H@33208|Metazoa,3CRRP@33213|Bilateria,481JI@7711|Chordata,4977N@7742|Vertebrata,3JA8Z@40674|Mammalia,4J3EB@91561|Cetartiodactyla	33208|Metazoa	O	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit	DDOST	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005765,GO:0005766,GO:0005773,GO:0005774,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0006996,GO:0007030,GO:0008150,GO:0008152,GO:0008250,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010033,GO:0010256,GO:0012505,GO:0012506,GO:0016020,GO:0016043,GO:0016192,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0030141,GO:0030659,GO:0030667,GO:0031090,GO:0031410,GO:0031982,GO:0031984,GO:0032940,GO:0032991,GO:0034097,GO:0034389,GO:0034645,GO:0035577,GO:0036211,GO:0036230,GO:0042110,GO:0042119,GO:0042175,GO:0042221,GO:0042582,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043299,GO:0043312,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046649,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0070085,GO:0071704,GO:0071840,GO:0071944,GO:0097708,GO:0098588,GO:0098796,GO:0098805,GO:0098827,GO:0098852,GO:0099503,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990234	-	ko:K12670	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	-	-	ko00000,ko00001,ko00002	-	-	-	DDOST_48kD
k59_649870_1	340177.Cag_1058	8.91e-64	207.0	COG2038@1|root,COG2038@2|Bacteria,1FD5I@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
k59_337064_1	991905.SL003B_3515	1.95e-87	276.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TSTS@28211|Alphaproteobacteria,4BPXA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	sfuB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
k59_102993_1	391735.Veis_0428	1.66e-10	62.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VKGS@28216|Betaproteobacteria,4ACHA@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_102993_2	330084.JNYZ01000004_gene609	2.17e-39	142.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DXFX@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_1181702_1	1128427.KB904821_gene1848	4.11e-18	89.4	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
k59_593637_1	1286171.EAL2_c16130	6.32e-13	70.1	COG0589@1|root,COG0589@2|Bacteria,1VZCK@1239|Firmicutes,253YG@186801|Clostridia,25Z3J@186806|Eubacteriaceae	2|Bacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_985824_1	631362.Thi970DRAFT_02956	6.43e-55	195.0	COG0457@1|root,COG2319@1|root,COG0457@2|Bacteria,COG2319@2|Bacteria,1N06S@1224|Proteobacteria,1S516@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MTH538 TIR-like domain (DUF1863)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1863,WD40
k59_828609_1	177437.HRM2_06650	3.08e-48	170.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2WIWY@28221|Deltaproteobacteria,2MHR1@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_554396_1	1047013.AQSP01000115_gene354	4.5e-97	291.0	COG0451@1|root,COG0451@2|Bacteria,2NP15@2323|unclassified Bacteria	2|Bacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	uxs	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
k59_162789_1	96561.Dole_0148	3.7e-34	133.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2MJNR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_1220664_1	335543.Sfum_1830	2.18e-67	219.0	COG3581@1|root,COG3581@2|Bacteria,1N1N8@1224|Proteobacteria,42UB7@68525|delta/epsilon subdivisions,2WQ9V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1028298_1	395495.Lcho_3889	2.69e-67	225.0	COG0683@1|root,COG2010@1|root,COG0683@2|Bacteria,COG2010@2|Bacteria,1R9N0@1224|Proteobacteria,2VZFH@28216|Betaproteobacteria,1KNA7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Peripla_BP_6
k59_244110_1	298386.PBPRA0056	1.98e-96	288.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1XT6R@135623|Vibrionales	135623|Vibrionales	J	glycyl-trna synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
k59_126550_1	404380.Gbem_3760	1.66e-11	62.4	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,42MJW@68525|delta/epsilon subdivisions,2WMYI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
k59_126550_2	933262.AXAM01000005_gene2494	9.24e-95	288.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,42MAU@68525|delta/epsilon subdivisions,2WK22@28221|Deltaproteobacteria,2MI2Y@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
k59_1066680_2	1127673.GLIP_3649	1.02e-25	101.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,1RN1A@1236|Gammaproteobacteria,46A7S@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_165668_1	1479237.JMLY01000001_gene844	3.7e-105	312.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RN4D@1236|Gammaproteobacteria,465KQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG1064 Zn-dependent alcohol dehydrogenases	yahK	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_989014_1	96561.Dole_2586	4.13e-43	163.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2MI69@213118|Desulfobacterales	28221|Deltaproteobacteria	D	DNA segregation ATPase, FtsK SpoIIIE family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
k59_322187_1	90814.KL370891_gene1367	8.78e-48	166.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,45ZPH@72273|Thiotrichales	72273|Thiotrichales	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
k59_322187_2	1120963.KB894492_gene1651	4.56e-09	57.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization activation	ymdB	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231	-	-	-	-	-	-	-	-	-	-	Macro
k59_753182_1	1056512.D515_01964	5.31e-18	80.1	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1S6G7@1236|Gammaproteobacteria,1XV3H@135623|Vibrionales	135623|Vibrionales	S	membrane	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
k59_753182_2	1123401.JHYQ01000009_gene2282	1.82e-33	124.0	COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,1SB70@1236|Gammaproteobacteria	1236|Gammaproteobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	dcsG	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP,RimK
k59_439950_1	1499967.BAYZ01000006_gene5461	6.9e-67	213.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
k59_870616_2	593907.Celgi_2468	3.27e-15	76.3	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4F0IJ@85016|Cellulomonadaceae	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
k59_1223875_2	1121405.dsmv_3225	1.05e-34	134.0	COG0031@1|root,COG0215@1|root,COG0031@2|Bacteria,COG0215@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria,2MIN1@213118|Desulfobacterales	28221|Deltaproteobacteria	J	cysteinyl-tRNA synthetase	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
k59_909763_1	335543.Sfum_3313	1.71e-57	189.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,2MQEZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
k59_204592_1	335543.Sfum_2565	3.47e-106	327.0	COG1614@1|root,COG1614@2|Bacteria,1MVI5@1224|Proteobacteria,42N9A@68525|delta/epsilon subdivisions,2WK4H@28221|Deltaproteobacteria,2MQWJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit	-	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
k59_753211_1	1112214.AHIS01000101_gene1685	4.47e-19	84.0	COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,2U773@28211|Alphaproteobacteria,2K1IN@204457|Sphingomonadales	204457|Sphingomonadales	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	1.14.11.2	ko:K00472	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
k59_714243_2	580332.Slit_2219	5.99e-52	178.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,44V1P@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_557438_1	314285.KT71_14674	1.15e-71	239.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1J8BZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Patched family	IV02_10640	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_439996_1	329726.AM1_2477	2.36e-80	247.0	COG2801@1|root,COG2801@2|Bacteria,1G5GD@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
k59_1223935_1	1232410.KI421416_gene2600	2.3e-45	161.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42NTB@68525|delta/epsilon subdivisions,2WKNX@28221|Deltaproteobacteria,43U98@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
k59_165757_1	177437.HRM2_41830	5.65e-29	118.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_596853_1	439235.Dalk_1820	2.05e-60	204.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,42NZH@68525|delta/epsilon subdivisions,2WKHB@28221|Deltaproteobacteria,2MISZ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Cytochrome c, bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C554,Cytochrome_cB
k59_1106153_1	929712.KI912613_gene62	7.31e-56	189.0	COG2141@1|root,COG2141@2|Bacteria,2GJAN@201174|Actinobacteria,4CRJX@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
k59_675003_1	177437.HRM2_16520	2e-37	130.0	COG3411@1|root,COG3411@2|Bacteria,1N1N9@1224|Proteobacteria,42U7G@68525|delta/epsilon subdivisions,2WQFG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Ferredoxin	-	-	1.12.1.3	ko:K17992	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_283102_1	1279017.AQYJ01000026_gene65	2.85e-67	231.0	COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,1RSIG@1236|Gammaproteobacteria,46DC5@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
k59_792468_1	391615.ABSJ01000017_gene1678	5.59e-35	134.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_9028_1	1177154.Y5S_00946	2.26e-53	176.0	COG3897@1|root,COG3897@2|Bacteria,1RJUI@1224|Proteobacteria,1S6V9@1236|Gammaproteobacteria,1XKCT@135619|Oceanospirillales	135619|Oceanospirillales	S	COG2230 Cyclopropane fatty acid synthase and related methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16,Methyltransf_25
k59_126670_1	9606.ENSP00000290541	3.06e-191	530.0	KOG0185@1|root,KOG0185@2759|Eukaryota,38G4U@33154|Opisthokonta,3B964@33208|Metazoa,3CZ27@33213|Bilateria,47ZUD@7711|Chordata,497I3@7742|Vertebrata,3JCJQ@40674|Mammalia,35CIA@314146|Euarchontoglires,4MGNG@9443|Primates,4MTTS@9604|Hominidae	33208|Metazoa	O	Proteasome subunit	PSMB4	GO:0000226,GO:0000502,GO:0001530,GO:0002682,GO:0002683,GO:0002861,GO:0002862,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005839,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007098,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016043,GO:0016579,GO:0019538,GO:0019774,GO:0019941,GO:0022402,GO:0030163,GO:0031023,GO:0031347,GO:0031348,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032991,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0048519,GO:0048583,GO:0048585,GO:0050727,GO:0050728,GO:0050776,GO:0050777,GO:0050789,GO:0051603,GO:0065007,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0080134,GO:0097367,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K02736	ko03050,map03050	M00337,M00340	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
k59_792472_1	27679.XP_003942212.1	5.15e-244	670.0	COG0057@1|root,KOG0657@2759|Eukaryota,38DPH@33154|Opisthokonta,3BA6Z@33208|Metazoa,3CRFX@33213|Bilateria,4830I@7711|Chordata,48V9Y@7742|Vertebrata,3J1GB@40674|Mammalia,35GGT@314146|Euarchontoglires,4MKNQ@9443|Primates	33208|Metazoa	G	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain	GAPDH	GO:0000226,GO:0000740,GO:0000768,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006949,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0007275,GO:0007520,GO:0007525,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009605,GO:0009607,GO:0009620,GO:0009653,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0014902,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019899,GO:0019904,GO:0030016,GO:0030017,GO:0030018,GO:0030154,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031341,GO:0031343,GO:0031430,GO:0031640,GO:0031647,GO:0031672,GO:0031674,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0033500,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036211,GO:0042221,GO:0042592,GO:0042593,GO:0042692,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043086,GO:0043170,GO:0043207,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048284,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048646,GO:0048856,GO:0048869,GO:0048878,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0060359,GO:0060548,GO:0061024,GO:0061025,GO:0061061,GO:0061134,GO:0061135,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090174,GO:0090407,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0099080,GO:0099081,GO:0099512,GO:0140096,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901698,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113	1.2.1.12	ko:K00134,ko:K10705	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_440038_1	1123073.KB899241_gene2784	6.04e-24	105.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1X44R@135614|Xanthomonadales	135614|Xanthomonadales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_909836_1	439235.Dalk_1090	1.25e-53	179.0	COG2197@1|root,COG2197@2|Bacteria,1R4BK@1224|Proteobacteria,42NQ2@68525|delta/epsilon subdivisions,2WJ35@28221|Deltaproteobacteria,2MJ46@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_126685_1	1120985.AUMI01000004_gene1324	9.86e-25	107.0	COG0577@1|root,COG0577@2|Bacteria,1U388@1239|Firmicutes,4H32X@909932|Negativicutes	909932|Negativicutes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_9054_1	745014.OMB55_00002830	1.56e-51	170.0	COG2236@1|root,COG2236@2|Bacteria,1RAZS@1224|Proteobacteria,1S2IG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
k59_48296_2	68194.JNXR01000002_gene7162	2.05e-38	137.0	COG1064@1|root,COG1064@2|Bacteria,2GNNY@201174|Actinobacteria	201174|Actinobacteria	S	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_88103_1	29908.U7PSY7	1.14e-05	48.9	COG1225@1|root,2SC9F@2759|Eukaryota,3A2X5@33154|Opisthokonta,3P3J2@4751|Fungi,3QVZP@4890|Ascomycota,21A95@147550|Sordariomycetes	4751|Fungi	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_322334_1	880072.Desac_2166	5.42e-83	264.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2MRG4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
k59_518698_1	765910.MARPU_14500	3.59e-61	208.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1WWTA@135613|Chromatiales	135613|Chromatiales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_675073_1	589865.DaAHT2_0176	6.15e-92	276.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,42NZG@68525|delta/epsilon subdivisions,2WNX9@28221|Deltaproteobacteria,2MKZC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	cytochrome C oxidase mono-heme subunit FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixO
k59_636056_1	243159.AFE_2614	3.59e-27	113.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,2NC72@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
k59_362091_1	631362.Thi970DRAFT_03746	1.95e-22	95.1	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria	1224|Proteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1028564_1	1095769.CAHF01000010_gene1148	3.84e-27	110.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria,472TR@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_753332_1	935567.JAES01000009_gene1664	1.68e-22	98.2	COG0451@1|root,COG0451@2|Bacteria,1RB7F@1224|Proteobacteria,1S6UB@1236|Gammaproteobacteria,1X5HR@135614|Xanthomonadales	135614|Xanthomonadales	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
k59_126726_1	1380391.JIAS01000001_gene2815	7.22e-91	287.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,2TUJB@28211|Alphaproteobacteria,2JQGJ@204441|Rhodospirillales	204441|Rhodospirillales	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
k59_557533_1	9541.XP_005552913.1	0.0	1318.0	COG0326@1|root,KOG0019@2759|Eukaryota,38B7K@33154|Opisthokonta,3BFAG@33208|Metazoa,3CVM1@33213|Bilateria,4807Q@7711|Chordata,49154@7742|Vertebrata,3JAF8@40674|Mammalia,35M7B@314146|Euarchontoglires,4M923@9443|Primates,35ZDI@314294|Cercopithecoidea	33208|Metazoa	O	Heat shock protein	HSP90AB1	GO:0000003,GO:0000166,GO:0000226,GO:0000323,GO:0000578,GO:0000723,GO:0000902,GO:0000904,GO:0001505,GO:0001568,GO:0001654,GO:0001745,GO:0001751,GO:0001752,GO:0001754,GO:0001775,GO:0001817,GO:0001818,GO:0001882,GO:0001883,GO:0001884,GO:0001890,GO:0001932,GO:0001934,GO:0001944,GO:0001959,GO:0002134,GO:0002135,GO:0002252,GO:0002253,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002429,GO:0002431,GO:0002433,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002684,GO:0002757,GO:0002764,GO:0002768,GO:0003002,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005667,GO:0005694,GO:0005700,GO:0005705,GO:0005737,GO:0005739,GO:0005764,GO:0005765,GO:0005773,GO:0005774,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005903,GO:0006139,GO:0006259,GO:0006278,GO:0006355,GO:0006357,GO:0006403,GO:0006457,GO:0006518,GO:0006606,GO:0006607,GO:0006725,GO:0006805,GO:0006807,GO:0006810,GO:0006886,GO:0006887,GO:0006897,GO:0006909,GO:0006913,GO:0006914,GO:0006928,GO:0006950,GO:0006955,GO:0006970,GO:0006986,GO:0006996,GO:0007004,GO:0007010,GO:0007017,GO:0007028,GO:0007049,GO:0007098,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007314,GO:0007315,GO:0007316,GO:0007350,GO:0007351,GO:0007389,GO:0007399,GO:0007409,GO:0007417,GO:0007423,GO:0007465,GO:0008092,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008285,GO:0008293,GO:0008298,GO:0008358,GO:0008361,GO:0008595,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009409,GO:0009410,GO:0009628,GO:0009631,GO:0009651,GO:0009653,GO:0009790,GO:0009798,GO:0009880,GO:0009887,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009948,GO:0009952,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0009994,GO:0010033,GO:0010243,GO:0010468,GO:0010528,GO:0010529,GO:0010556,GO:0010557,GO:0010562,GO:0010564,GO:0010604,GO:0010605,GO:0010646,GO:0010647,GO:0010833,GO:0010921,GO:0010922,GO:0010941,GO:0010948,GO:0012505,GO:0014070,GO:0015031,GO:0015630,GO:0015833,GO:0016020,GO:0016032,GO:0016043,GO:0016049,GO:0016192,GO:0016234,GO:0016323,GO:0016324,GO:0016462,GO:0016477,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017015,GO:0017038,GO:0017076,GO:0017098,GO:0017111,GO:0018130,GO:0019001,GO:0019058,GO:0019062,GO:0019094,GO:0019103,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0019953,GO:0021700,GO:0021953,GO:0021954,GO:0021955,GO:0022008,GO:0022402,GO:0022412,GO:0022414,GO:0022607,GO:0022610,GO:0022613,GO:0022618,GO:0023051,GO:0023052,GO:0023056,GO:0030010,GO:0030030,GO:0030141,GO:0030154,GO:0030162,GO:0030163,GO:0030182,GO:0030234,GO:0030235,GO:0030424,GO:0030425,GO:0030426,GO:0030427,GO:0030511,GO:0030554,GO:0030911,GO:0031023,GO:0031072,GO:0031090,GO:0031175,GO:0031253,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031341,GO:0031342,GO:0031347,GO:0031396,GO:0031399,GO:0031401,GO:0031410,GO:0031526,GO:0031625,GO:0031647,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032092,GO:0032200,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032388,GO:0032434,GO:0032435,GO:0032501,GO:0032502,GO:0032504,GO:0032516,GO:0032535,GO:0032549,GO:0032550,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032557,GO:0032558,GO:0032559,GO:0032561,GO:0032564,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033135,GO:0033138,GO:0033157,GO:0033158,GO:0033160,GO:0033218,GO:0033267,GO:0033365,GO:0033554,GO:0033674,GO:0034097,GO:0034504,GO:0034605,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034654,GO:0034751,GO:0034774,GO:0035282,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035639,GO:0035690,GO:0035966,GO:0036094,GO:0036230,GO:0036477,GO:0038093,GO:0038094,GO:0038096,GO:0040007,GO:0040011,GO:0042119,GO:0042127,GO:0042176,GO:0042177,GO:0042220,GO:0042221,GO:0042277,GO:0042306,GO:0042307,GO:0042325,GO:0042327,GO:0042493,GO:0042592,GO:0042623,GO:0042706,GO:0042749,GO:0042752,GO:0042802,GO:0042803,GO:0042826,GO:0042886,GO:0042981,GO:0042995,GO:0043005,GO:0043008,GO:0043025,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043235,GO:0043248,GO:0043279,GO:0043299,GO:0043312,GO:0043393,GO:0043523,GO:0043524,GO:0043549,GO:0043603,GO:0043627,GO:0043666,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044292,GO:0044294,GO:0044295,GO:0044297,GO:0044325,GO:0044389,GO:0044403,GO:0044406,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044427,GO:0044428,GO:0044430,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044650,GO:0044703,GO:0045055,GO:0045088,GO:0045165,GO:0045177,GO:0045184,GO:0045187,GO:0045321,GO:0045428,GO:0045429,GO:0045466,GO:0045595,GO:0045597,GO:0045786,GO:0045787,GO:0045793,GO:0045859,GO:0045860,GO:0045861,GO:0045935,GO:0045937,GO:0046483,GO:0046530,GO:0046552,GO:0046677,GO:0046822,GO:0046824,GO:0046903,GO:0046907,GO:0046983,GO:0048156,GO:0048468,GO:0048469,GO:0048471,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048588,GO:0048589,GO:0048592,GO:0048599,GO:0048608,GO:0048609,GO:0048663,GO:0048666,GO:0048667,GO:0048675,GO:0048699,GO:0048731,GO:0048749,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050821,GO:0050896,GO:0050900,GO:0051049,GO:0051050,GO:0051052,GO:0051054,GO:0051082,GO:0051094,GO:0051098,GO:0051099,GO:0051131,GO:0051169,GO:0051170,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051276,GO:0051336,GO:0051338,GO:0051345,GO:0051347,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051716,GO:0051726,GO:0051896,GO:0051897,GO:0051972,GO:0051973,GO:0055085,GO:0060205,GO:0060249,GO:0060255,GO:0060330,GO:0060334,GO:0060338,GO:0060341,GO:0060359,GO:0060548,GO:0060560,GO:0060759,GO:0060810,GO:0060811,GO:0061136,GO:0061458,GO:0061564,GO:0061635,GO:0061684,GO:0061741,GO:0061827,GO:0061919,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070182,GO:0070201,GO:0070670,GO:0070727,GO:0070887,GO:0071156,GO:0071157,GO:0071310,GO:0071345,GO:0071353,GO:0071407,GO:0071466,GO:0071634,GO:0071635,GO:0071702,GO:0071704,GO:0071705,GO:0071806,GO:0071826,GO:0071840,GO:0071897,GO:0071900,GO:0071902,GO:0071944,GO:0072321,GO:0072347,GO:0072358,GO:0072359,GO:0072594,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0090087,GO:0090092,GO:0090100,GO:0090287,GO:0090304,GO:0090316,GO:0090596,GO:0097159,GO:0097223,GO:0097367,GO:0097435,GO:0097447,GO:0097458,GO:0097524,GO:0097708,GO:0097718,GO:0098588,GO:0098590,GO:0098657,GO:0098687,GO:0098772,GO:0098805,GO:0098852,GO:0098862,GO:0099503,GO:0101002,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:1900034,GO:1900180,GO:1900182,GO:1901214,GO:1901215,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901388,GO:1901389,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901698,GO:1901700,GO:1901799,GO:1902531,GO:1902533,GO:1902947,GO:1902949,GO:1903050,GO:1903051,GO:1903320,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903659,GO:1903660,GO:1903827,GO:1903829,GO:1903844,GO:1903846,GO:1904029,GO:1904031,GO:1904407,GO:1904589,GO:1904591,GO:1904813,GO:1904951,GO:1905323,GO:1990138,GO:1990226,GO:1990913,GO:1990917,GO:2000008,GO:2000010,GO:2000058,GO:2000059,GO:2000112,GO:2000278,GO:2000377,GO:2000379,GO:2000573,GO:2001141	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HSP90
k59_88156_1	443152.MDG893_12199	2.71e-56	197.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RNWM@1236|Gammaproteobacteria,465X0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_636089_1	314278.NB231_01359	3.22e-70	237.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
k59_440120_1	745411.B3C1_16004	1.61e-100	311.0	COG4805@1|root,COG4805@2|Bacteria,1PIM6@1224|Proteobacteria,1RRW7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_1184752_1	96561.Dole_2419	4.14e-25	107.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,2MJFK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
k59_440145_1	1382306.JNIM01000001_gene3512	1.85e-34	134.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
k59_949377_1	1042209.HK44_021600	1.64e-59	196.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,1RRMU@1236|Gammaproteobacteria,1YU3Y@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	L	Endonuclease DDE	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_32
k59_165922_1	713586.KB900536_gene571	3.53e-07	50.4	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,1RNH2@1236|Gammaproteobacteria,1WWM8@135613|Chromatiales	135613|Chromatiales	IQ	TIGRFAM acetoacetyl-CoA reductase	-	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
k59_165922_2	190486.XAC2402	2.2e-41	144.0	COG5394@1|root,COG5394@2|Bacteria,1RFY3@1224|Proteobacteria,1S3W3@1236|Gammaproteobacteria,1X66E@135614|Xanthomonadales	135614|Xanthomonadales	S	synthesis repressor, PhaR	phaR	-	-	-	-	-	-	-	-	-	-	-	PHB_acc,PHB_acc_N
k59_518795_1	224914.BMEII0228	1.31e-86	264.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2U0FG@28211|Alphaproteobacteria,1J33W@118882|Brucellaceae	28211|Alphaproteobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_518795_2	1007104.SUS17_4081	6.27e-21	86.7	COG2963@1|root,COG2963@2|Bacteria,1N0AJ@1224|Proteobacteria,2UDRV@28211|Alphaproteobacteria,2K7MF@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_949389_1	51337.XP_004661700.1	1.5e-81	242.0	COG5262@1|root,KOG1757@2759|Eukaryota,39ZW3@33154|Opisthokonta,3BPC4@33208|Metazoa,3D68R@33213|Bilateria,48E2D@7711|Chordata,49ATP@7742|Vertebrata,3JGJM@40674|Mammalia,35PXB@314146|Euarchontoglires,4Q5BA@9989|Rodentia	33208|Metazoa	B	Histone H2A.Z-like	H2AFZ	GO:0000228,GO:0000785,GO:0000786,GO:0000790,GO:0000791,GO:0000792,GO:0000793,GO:0000976,GO:0000977,GO:0000978,GO:0000979,GO:0000980,GO:0000987,GO:0001012,GO:0001046,GO:0001047,GO:0001067,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005700,GO:0005701,GO:0005719,GO:0005720,GO:0006325,GO:0006342,GO:0006355,GO:0006357,GO:0006996,GO:0008104,GO:0008150,GO:0009719,GO:0009725,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009996,GO:0010033,GO:0010243,GO:0010369,GO:0010453,GO:0010454,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0014070,GO:0016043,GO:0016458,GO:0019219,GO:0019222,GO:0019827,GO:0030718,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031490,GO:0031491,GO:0031492,GO:0031974,GO:0031981,GO:0032355,GO:0032501,GO:0032502,GO:0032868,GO:0032869,GO:0032870,GO:0032991,GO:0032993,GO:0033036,GO:0033365,GO:0033993,GO:0034502,GO:0034613,GO:0035019,GO:0035326,GO:0035861,GO:0036098,GO:0040029,GO:0042221,GO:0042659,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043434,GO:0043565,GO:0044212,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044815,GO:0044877,GO:0045595,GO:0045596,GO:0045814,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051093,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051641,GO:0051716,GO:0060255,GO:0065007,GO:0070013,GO:0070727,GO:0070887,GO:0071168,GO:0071310,GO:0071375,GO:0071392,GO:0071396,GO:0071407,GO:0071417,GO:0071495,GO:0071840,GO:0080090,GO:0090734,GO:0097159,GO:0098687,GO:0098727,GO:1901363,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K11251	ko04217,ko05034,ko05322,map04217,map05034,map05322	-	-	-	ko00000,ko00001,ko03036,ko04147	-	-	-	Histone,Histone_H2A_C
k59_88211_1	706587.Desti_3731	4.57e-35	125.0	COG0745@1|root,COG0745@2|Bacteria,1MZPD@1224|Proteobacteria,42U2Y@68525|delta/epsilon subdivisions,2WQ1I@28221|Deltaproteobacteria,2MRWP@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Usp
k59_1106321_1	86106.I862_02625	7.04e-19	90.5	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,47F0K@766|Rickettsiales	766|Rickettsiales	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	pleD	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
k59_636143_1	977880.RALTA_A0488	4.74e-70	227.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1K3N3@119060|Burkholderiaceae	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_9181_1	1265505.ATUG01000001_gene4389	4.05e-21	89.4	COG1595@1|root,COG1595@2|Bacteria,1PEU8@1224|Proteobacteria,42T76@68525|delta/epsilon subdivisions,2WPVH@28221|Deltaproteobacteria,2MM35@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_597041_1	1120972.AUMH01000004_gene1385	1.01e-89	271.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,279A5@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK5	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_714572_1	266835.14024743	4.79e-45	164.0	COG4178@1|root,COG4178@2|Bacteria,1MW09@1224|Proteobacteria,2TS9Q@28211|Alphaproteobacteria,43GTX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	transport system, permease and ATPase	MA20_43525	-	-	ko:K02471	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.203.11,3.A.1.203.4	-	-	ABC_membrane_2,ABC_tran
k59_165951_1	411902.CLOBOL_01808	5.86e-07	51.6	COG1063@1|root,COG1063@2|Bacteria,1UI0K@1239|Firmicutes,24ATX@186801|Clostridia,220EH@1506553|Lachnoclostridium	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k59_165951_2	264732.Moth_2268	1.31e-08	55.1	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,42FBE@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
k59_675224_1	933262.AXAM01000034_gene1563	1.63e-20	90.1	COG2885@1|root,COG3267@1|root,COG2885@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42PJ3@68525|delta/epsilon subdivisions,2WJF6@28221|Deltaproteobacteria,2MJ4S@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	AAA domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,OmpA
k59_189488_1	1123073.KB899241_gene2771	1.64e-20	92.8	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,1S612@1236|Gammaproteobacteria,1X69I@135614|Xanthomonadales	135614|Xanthomonadales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
k59_72014_1	590998.Celf_1186	1.41e-25	104.0	COG0366@1|root,COG0366@2|Bacteria,2GNEC@201174|Actinobacteria	201174|Actinobacteria	G	Alpha amylase, catalytic domain	gtfA	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF1964
k59_72014_2	314285.KT71_11054	3.41e-105	328.0	COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,1MXVP@1224|Proteobacteria,1RS4C@1236|Gammaproteobacteria,1J8VP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	TonB dependent receptor	suxA	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1209788_1	857087.Metme_0486	1.09e-43	154.0	COG1638@1|root,COG1638@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
k59_582467_1	536232.CLM_1465	4.26e-21	94.7	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,36EIR@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
k59_1018244_1	96561.Dole_2809	2.86e-14	73.2	COG3678@1|root,COG3678@2|Bacteria,1N8UD@1224|Proteobacteria,42WAR@68525|delta/epsilon subdivisions,2WRQX@28221|Deltaproteobacteria,2MM0V@213118|Desulfobacterales	28221|Deltaproteobacteria	NPTU	Heavy-metal resistance	-	-	-	ko:K07803	ko02020,map02020	-	-	-	ko00000,ko00001,ko03110	-	-	-	Metal_resist
k59_464558_1	246195.DNO_1178	5.46e-48	160.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_1209814_2	316056.RPC_0689	4.56e-71	224.0	COG3396@1|root,COG3396@2|Bacteria,1MVYQ@1224|Proteobacteria,2TRYF@28211|Alphaproteobacteria,3JUK9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Phenylacetic acid catabolic protein	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
k59_189544_1	395494.Galf_0345	4.03e-14	74.7	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,44V1H@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_189544_2	1224318.DT73_07415	1.16e-33	121.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	belongs to the nudix hydrolase family	mutT	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	iE2348C_1286.E2348C_0104,iSDY_1059.SDY_0129	NUDIX,NUDIX_4,TMP-TENI
k59_189544_3	246195.DNO_0301	1.48e-05	47.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044424,GO:0044444,GO:0044464,GO:0051301	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
k59_464572_1	1118153.MOY_09815	1.92e-24	105.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,1XHSC@135619|Oceanospirillales	135619|Oceanospirillales	P	Iron deficiency-induced protein A	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
k59_738828_1	1957.JODX01000007_gene2278	7.47e-20	90.1	COG2519@1|root,COG2519@2|Bacteria,2GMKZ@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
k59_1251781_1	404589.Anae109_3891	5.31e-56	196.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42QJP@68525|delta/epsilon subdivisions,2WMET@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2
k59_388160_1	1397527.Q670_02785	9.55e-52	184.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,1XHC0@135619|Oceanospirillales	135619|Oceanospirillales	E	Oligopeptidase	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_347753_2	1267005.KB911255_gene2565	2.66e-51	177.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2TQU6@28211|Alphaproteobacteria,3N6CH@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	Mg chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
k59_1090808_1	247634.GPB2148_2617	3.15e-76	241.0	COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,1RRPK@1236|Gammaproteobacteria,1J8VU@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Beta-glucanase Beta-glucan synthetase	bglA	-	-	-	-	-	-	-	-	-	-	-	CBM_2,DUF5011,Glyco_hydro_16,Malectin,RicinB_lectin_2
k59_1018289_1	946483.Cenrod_1715	5.01e-36	139.0	COG1729@1|root,COG5617@1|root,COG1729@2|Bacteria,COG5617@2|Bacteria,1RBCY@1224|Proteobacteria	1224|Proteobacteria	S	6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
k59_1090826_1	298386.PBPRA1265	8.37e-73	239.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,1RMHR@1236|Gammaproteobacteria,1XUC7@135623|Vibrionales	135623|Vibrionales	Q	COG2015 Alkyl sulfatase and related hydrolases	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
k59_546907_1	391937.NA2_02674	2.39e-96	295.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSG6@28211|Alphaproteobacteria,43GWF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Glycolate oxidase subunit GlcD	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_659731_1	563040.Saut_0384	2.06e-62	206.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2YTNK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Phospholipase D Active site motif	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_659731_2	398578.Daci_1518	1.66e-13	72.4	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2VJ3B@28216|Betaproteobacteria,4AAQE@80864|Comamonadaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
k59_388193_1	941449.dsx2_3330	6.34e-40	142.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NS4@68525|delta/epsilon subdivisions,2WJT9@28221|Deltaproteobacteria,2MGEK@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
k59_738853_1	395961.Cyan7425_3878	8.96e-87	272.0	COG0438@1|root,COG0438@2|Bacteria,1G271@1117|Cyanobacteria,3KH3R@43988|Cyanothece	1117|Cyanobacteria	H	Glycosyl transferase 4-like domain	icsA	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
k59_778188_1	1049564.TevJSym_bb00030	6.92e-21	94.7	COG1013@1|root,COG1013@2|Bacteria,1R28U@1224|Proteobacteria	1224|Proteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
k59_1018305_1	1089552.KI911559_gene2278	1.7e-19	93.2	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TRIR@28211|Alphaproteobacteria,2JQ76@204441|Rhodospirillales	204441|Rhodospirillales	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	-	-	-	ko:K05559,ko:K05565	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
k59_933938_1	118797.XP_007468251.1	1.47e-90	296.0	COG0085@1|root,KOG0214@2759|Eukaryota	2759|Eukaryota	K	DNA-directed 5'-3' RNA polymerase activity	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_308577_1	1517416.IDAT_06025	1.25e-65	223.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,2QFUY@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_1090854_1	1328313.DS2_08605	8.74e-12	67.8	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,465AJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1090876_1	761193.Runsl_2787	8.03e-09	61.6	COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47QEI@768503|Cytophagia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
k59_699963_1	399739.Pmen_0662	1.1e-53	179.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,1S3SX@1236|Gammaproteobacteria,1YHMZ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
k59_546944_1	1267533.KB906733_gene3170	1.51e-102	323.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
k59_1251879_1	214092.YPO1590	2.46e-31	127.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,41F3S@629|Yersinia	1236|Gammaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	GO:0000287,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008312,GO:0008995,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0017151,GO:0019222,GO:0019439,GO:0019899,GO:0022607,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043462,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048519,GO:0050789,GO:0050790,GO:0051095,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902280	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	PNPase_C,RNase_E_G,S1
k59_816003_1	96561.Dole_1382	1.15e-95	285.0	COG1600@1|root,COG1600@2|Bacteria,1NW4X@1224|Proteobacteria,4300M@68525|delta/epsilon subdivisions,2WVFS@28221|Deltaproteobacteria,2MNF3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_33426_1	1122185.N792_11485	2.81e-17	92.4	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RQM3@1236|Gammaproteobacteria,1X4AK@135614|Xanthomonadales	135614|Xanthomonadales	I	Cardiolipin synthase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
k59_1170634_1	1122132.AQYH01000006_gene3468	7.99e-38	144.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,4B8TA@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and or methyl galactoside import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
k59_504224_1	1333523.L593_02030	1.75e-33	135.0	COG0613@1|root,arCOG00302@2157|Archaea,2Y3UJ@28890|Euryarchaeota,23ZRF@183963|Halobacteria	183963|Halobacteria	S	metal-dependent phosphoesterases (PHP family)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_150754_2	525903.Taci_1702	2.25e-31	120.0	COG0075@1|root,COG0075@2|Bacteria,3TA05@508458|Synergistetes	508458|Synergistetes	E	PFAM Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_1131115_2	756272.Plabr_3569	1.65e-41	147.0	COG0515@1|root,COG0515@2|Bacteria,2IZFV@203682|Planctomycetes	203682|Planctomycetes	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_622204_1	83406.HDN1F_23210	2.32e-93	286.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1J4DE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0006457,GO:0008150,GO:0009987	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_464693_1	179408.Osc7112_1555	7.01e-06	54.3	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG2770@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
k59_1056052_1	1082933.MEA186_10801	2.79e-32	119.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,2U5JH@28211|Alphaproteobacteria,43P9Z@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
k59_1056052_2	698761.RTCIAT899_CH09425	5.67e-06	49.3	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TRCV@28211|Alphaproteobacteria,4B9ZR@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the peptidase S11 family	dac	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Peptidase_S11,SPOR
k59_74265_1	1121943.KB899999_gene1346	3.34e-32	123.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1XI3G@135619|Oceanospirillales	135619|Oceanospirillales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_662064_1	9606.ENSP00000391481	7.42e-205	582.0	COG0021@1|root,KOG0523@2759|Eukaryota,38B8B@33154|Opisthokonta,3BG4D@33208|Metazoa,3CXK5@33213|Bilateria,484SM@7711|Chordata,48VMD@7742|Vertebrata,3J4DW@40674|Mammalia,35JEY@314146|Euarchontoglires,4MHHT@9443|Primates,4MZ86@9604|Hominidae	33208|Metazoa	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	TKT	GO:0000287,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005777,GO:0005783,GO:0005789,GO:0005829,GO:0005975,GO:0005996,GO:0005997,GO:0005999,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009058,GO:0009117,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0012505,GO:0016020,GO:0016051,GO:0016604,GO:0016607,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019321,GO:0019322,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030246,GO:0030976,GO:0031323,GO:0031326,GO:0031935,GO:0031974,GO:0031981,GO:0031984,GO:0033043,GO:0033044,GO:0034641,GO:0036094,GO:0040008,GO:0042175,GO:0042579,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046166,GO:0046184,GO:0046364,GO:0046390,GO:0046483,GO:0046496,GO:0046872,GO:0046983,GO:0048029,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0051128,GO:0051156,GO:0051171,GO:0051186,GO:0051252,GO:0055086,GO:0060255,GO:0060968,GO:0065007,GO:0070013,GO:0071704,GO:0072524,GO:0080090,GO:0090407,GO:0097159,GO:0098827,GO:1901135,GO:1901137,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901681,GO:1902275,GO:1903506,GO:2000112,GO:2001141	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_780609_1	1056820.KB900643_gene851	9.82e-133	385.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1RUI0@1236|Gammaproteobacteria,2PN0P@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
k59_858596_2	1121422.AUMW01000010_gene1036	7.13e-36	130.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,26121@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17,4.2.1.18	ko:K01715,ko:K13766	ko00280,ko00650,ko01100,ko01200,map00280,map00650,map01100,map01200	M00036	R02085,R03026	RC00831,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_152782_1	933262.AXAM01000024_gene741	1.42e-80	248.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,42M16@68525|delta/epsilon subdivisions,2WM0V@28221|Deltaproteobacteria,2MKMA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Amino acid kinase family	cpkA	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_702283_1	1131814.JAFO01000001_gene1814	2.66e-11	65.1	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,3EZZS@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Patatin-like phospholipase	rssA	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
k59_741378_1	443143.GM18_3590	8.38e-24	107.0	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,42Z3A@68525|delta/epsilon subdivisions,2WUES@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
k59_741391_1	1232410.KI421428_gene1022	3.8e-54	179.0	COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,42W88@68525|delta/epsilon subdivisions,2WRBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
k59_191942_1	1454004.AW11_03981	1.58e-42	151.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2VIN1@28216|Betaproteobacteria,1KR64@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	ET	PFAM extracellular solute-binding protein family 3	aapJ	-	-	ko:K02030,ko:K09969,ko:K10001	ko02010,ko02020,map02010,map02020	M00230,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.18,3.A.1.3.19,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
k59_191943_1	933262.AXAM01000036_gene2181	2.41e-90	294.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2MI3P@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_74362_1	765912.Thimo_1722	1.87e-82	267.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k59_1133341_1	1122929.KB908215_gene1060	6.33e-56	185.0	COG0647@1|root,COG0647@2|Bacteria,1MU9Y@1224|Proteobacteria,2TUH0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	sugar phosphatases of the HAD superfamily	MA20_05625	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
k59_702328_1	977880.RALTA_A2392	1.61e-35	132.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria,1K2JJ@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
k59_1093231_1	477974.Daud_1926	1.72e-54	190.0	COG0574@1|root,COG3605@1|root,COG0574@2|Bacteria,COG3605@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia	186801|Clostridia	GT	pyruvate phosphate dikinase, PEP	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_310896_1	1304885.AUEY01000047_gene77	5.05e-82	255.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2MHV9@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_624655_1	1278307.KB906970_gene1102	8.54e-33	127.0	COG5361@1|root,COG5361@2|Bacteria	1278307.KB906970_gene1102|-	P	Conserved Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_152852_1	164757.Mjls_3329	3.88e-15	81.3	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,2370G@1762|Mycobacteriaceae	201174|Actinobacteria	S	amidohydrolase	nfdA_1	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_585105_1	765912.Thimo_3336	4.33e-37	137.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1T2DW@1236|Gammaproteobacteria,1X2PB@135613|Chromatiales	135613|Chromatiales	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
k59_390557_1	1126627.BAWE01000006_gene6551	1.31e-65	223.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,3JXXJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	sardh	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
k59_152869_1	27679.XP_003930339.1	6.65e-104	327.0	KOG1037@1|root,KOG1037@2759|Eukaryota,38B7U@33154|Opisthokonta,3BBUM@33208|Metazoa,3CT5Y@33213|Bilateria,4833Y@7711|Chordata,494V3@7742|Vertebrata,3J385@40674|Mammalia,35DHV@314146|Euarchontoglires,4MIVI@9443|Primates	33208|Metazoa	KLO	Poly (ADP-ribose) polymerase 1	PARP1	GO:0000002,GO:0000003,GO:0000122,GO:0000166,GO:0000228,GO:0000302,GO:0000303,GO:0000305,GO:0000715,GO:0000723,GO:0000724,GO:0000725,GO:0000785,GO:0000790,GO:0000791,GO:0000976,GO:0000977,GO:0000981,GO:0001012,GO:0001067,GO:0001228,GO:0001817,GO:0001818,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002225,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002791,GO:0002792,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003002,GO:0003006,GO:0003254,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0003824,GO:0003909,GO:0003910,GO:0003950,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005667,GO:0005694,GO:0005700,GO:0005703,GO:0005719,GO:0005730,GO:0005737,GO:0005739,GO:0006139,GO:0006140,GO:0006163,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006293,GO:0006294,GO:0006296,GO:0006302,GO:0006310,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006464,GO:0006471,GO:0006508,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006963,GO:0006974,GO:0006979,GO:0006996,GO:0006997,GO:0007000,GO:0007005,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007389,GO:0007552,GO:0007610,GO:0008069,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009303,GO:0009314,GO:0009408,GO:0009410,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009798,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009950,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010043,GO:0010212,GO:0010243,GO:0010332,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010611,GO:0010613,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010990,GO:0012501,GO:0012505,GO:0014070,GO:0014742,GO:0014743,GO:0015030,GO:0016043,GO:0016070,GO:0016072,GO:0016333,GO:0016334,GO:0016485,GO:0016540,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016886,GO:0017144,GO:0018130,GO:0018193,GO:0018209,GO:0018312,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0022616,GO:0023019,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030099,GO:0030154,GO:0030225,GO:0030331,GO:0030534,GO:0030575,GO:0030576,GO:0030707,GO:0030808,GO:0030809,GO:0030855,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031334,GO:0031347,GO:0031349,GO:0031960,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032042,GO:0032101,GO:0032103,GO:0032200,GO:0032204,GO:0032205,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032660,GO:0032700,GO:0032774,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033044,GO:0033143,GO:0033145,GO:0033146,GO:0033148,GO:0033365,GO:0033554,GO:0033683,GO:0033993,GO:0034248,GO:0034250,GO:0034504,GO:0034599,GO:0034605,GO:0034613,GO:0034614,GO:0034622,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034660,GO:0035079,GO:0035080,GO:0035257,GO:0035258,GO:0035363,GO:0036094,GO:0036211,GO:0040008,GO:0040009,GO:0042220,GO:0042221,GO:0042391,GO:0042393,GO:0042493,GO:0042592,GO:0042769,GO:0042802,GO:0042826,GO:0042981,GO:0043067,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043279,GO:0043388,GO:0043412,GO:0043434,GO:0043484,GO:0043502,GO:0043504,GO:0043523,GO:0043565,GO:0043900,GO:0043902,GO:0043933,GO:0044030,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0045087,GO:0045185,GO:0045595,GO:0045597,GO:0045739,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0045980,GO:0046034,GO:0046332,GO:0046483,GO:0047485,GO:0048037,GO:0048148,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048545,GO:0048583,GO:0048584,GO:0048609,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050707,GO:0050708,GO:0050709,GO:0050710,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050879,GO:0050881,GO:0050882,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051052,GO:0051053,GO:0051054,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051103,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051287,GO:0051385,GO:0051427,GO:0051457,GO:0051604,GO:0051606,GO:0051641,GO:0051651,GO:0051704,GO:0051716,GO:0051881,GO:0051900,GO:0051901,GO:0055086,GO:0060249,GO:0060255,GO:0060341,GO:0060359,GO:0060390,GO:0060391,GO:0060429,GO:0062012,GO:0062014,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070212,GO:0070412,GO:0070727,GO:0070848,GO:0070887,GO:0070911,GO:0071214,GO:0071241,GO:0071248,GO:0071294,GO:0071310,GO:0071363,GO:0071375,GO:0071417,GO:0071450,GO:0071451,GO:0071478,GO:0071482,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071824,GO:0071840,GO:0072347,GO:0072521,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090092,GO:0090100,GO:0090257,GO:0090304,GO:0090305,GO:0097159,GO:0097305,GO:0097659,GO:0098687,GO:0098781,GO:0104004,GO:0140096,GO:0140097,GO:0140110,GO:1900180,GO:1900182,GO:1900371,GO:1900372,GO:1900407,GO:1900424,GO:1900426,GO:1900542,GO:1900543,GO:1901135,GO:1901214,GO:1901216,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901652,GO:1901653,GO:1901654,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902175,GO:1902531,GO:1902679,GO:1902680,GO:1902882,GO:1903201,GO:1903203,GO:1903376,GO:1903506,GO:1903507,GO:1903508,GO:1903516,GO:1903518,GO:1903530,GO:1903531,GO:1903578,GO:1903579,GO:1903827,GO:1903829,GO:1904044,GO:1904181,GO:1904356,GO:1904357,GO:1904645,GO:1904646,GO:1904760,GO:1904762,GO:1904950,GO:1905076,GO:1905077,GO:1990404,GO:1990837,GO:1990966,GO:2000112,GO:2000113,GO:2000677,GO:2000679,GO:2001020,GO:2001022,GO:2001141,GO:2001169,GO:2001170,GO:2001233,GO:2001242,GO:2001251	2.4.2.30	ko:K10798	ko03410,ko04210,ko04212,ko04214,ko04217,map03410,map04210,map04212,map04214,map04217	M00296	-	-	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400	-	-	-	BRCT,PADR1,PARP,PARP_reg,WGR,zf-PARP
k59_1212305_1	1279017.AQYJ01000029_gene3711	1.41e-92	300.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4643G@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_898681_1	444861.E3SPM2_9CAUD	3.12e-110	337.0	4QAR1@10239|Viruses,4QUNA@35237|dsDNA viruses  no RNA stage,4QPJE@28883|Caudovirales	28883|Caudovirales	S	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_977906_1	1232410.KI421421_gene3858	1.3e-32	129.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TBV@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PASTA domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
k59_977906_2	56780.SYN_01738	7e-09	55.8	COG3116@1|root,COG3116@2|Bacteria	2|Bacteria	D	cell division	ftsL	GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
k59_585172_1	1121405.dsmv_3781	3.98e-113	335.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
k59_35911_1	765912.Thimo_1465	2.44e-30	115.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,1RY2B@1236|Gammaproteobacteria,1WY1Q@135613|Chromatiales	135613|Chromatiales	S	PFAM transport-associated	-	-	-	-	-	-	-	-	-	-	-	-	BON
k59_1133447_2	292415.Tbd_2479	1.82e-55	180.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
k59_1042719_2	247634.GPB2148_3743	9.72e-34	121.0	COG4764@1|root,COG4764@2|Bacteria,1MVRK@1224|Proteobacteria,1RQ79@1236|Gammaproteobacteria,1J5V9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SLT
k59_569597_1	314285.KT71_08620	3.86e-106	317.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1J9WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
k59_883147_1	10029.XP_007637920.1	1.66e-117	347.0	COG5648@1|root,KOG0381@2759|Eukaryota,39V7D@33154|Opisthokonta,3BI6Q@33208|Metazoa,3D06X@33213|Bilateria,48QDJ@7711|Chordata,49KZS@7742|Vertebrata,3J2AM@40674|Mammalia,35EJ8@314146|Euarchontoglires,4PWF7@9989|Rodentia	33208|Metazoa	K	non-sequence-specific DNA binding, bending	HMGB2	GO:0000003,GO:0000217,GO:0000228,GO:0000400,GO:0000737,GO:0000785,GO:0000790,GO:0000793,GO:0000976,GO:0001067,GO:0001158,GO:0001708,GO:0001936,GO:0001938,GO:0002119,GO:0002164,GO:0002200,GO:0002237,GO:0002376,GO:0002437,GO:0002520,GO:0002562,GO:0002682,GO:0002684,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003690,GO:0003697,GO:0003700,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0006139,GO:0006259,GO:0006265,GO:0006266,GO:0006281,GO:0006308,GO:0006309,GO:0006310,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006338,GO:0006355,GO:0006357,GO:0006725,GO:0006807,GO:0006915,GO:0006921,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006974,GO:0006996,GO:0006997,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007289,GO:0007399,GO:0007548,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008289,GO:0008301,GO:0008406,GO:0008584,GO:0009056,GO:0009057,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010469,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010648,GO:0010941,GO:0012501,GO:0014070,GO:0016043,GO:0016055,GO:0016444,GO:0016477,GO:0019219,GO:0019222,GO:0019439,GO:0019904,GO:0019953,GO:0022008,GO:0022411,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030262,GO:0030545,GO:0031099,GO:0031100,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031491,GO:0031493,GO:0031497,GO:0031974,GO:0031981,GO:0032069,GO:0032075,GO:0032392,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033151,GO:0033554,GO:0033993,GO:0034622,GO:0034641,GO:0034655,GO:0034728,GO:0035326,GO:0040011,GO:0040025,GO:0042056,GO:0042127,GO:0042221,GO:0042330,GO:0042393,GO:0042493,GO:0042742,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043388,GO:0043565,GO:0043933,GO:0044085,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044378,GO:0044421,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044703,GO:0044877,GO:0045137,GO:0045165,GO:0045595,GO:0045597,GO:0045637,GO:0045639,GO:0045646,GO:0045648,GO:0045652,GO:0045654,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046546,GO:0046661,GO:0046700,GO:0048018,GO:0048232,GO:0048468,GO:0048471,GO:0048513,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048569,GO:0048583,GO:0048585,GO:0048608,GO:0048609,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050767,GO:0050786,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050829,GO:0050830,GO:0050896,GO:0050918,GO:0051052,GO:0051054,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051103,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051239,GO:0051240,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051336,GO:0051345,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051960,GO:0060255,GO:0060284,GO:0060326,GO:0060548,GO:0061458,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070887,GO:0071103,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071396,GO:0071704,GO:0071824,GO:0071840,GO:0072091,GO:0080090,GO:0090304,GO:0090305,GO:0097100,GO:0097159,GO:0097194,GO:0098542,GO:0098772,GO:0140110,GO:0198738,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901700,GO:1901701,GO:1902041,GO:1902042,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1903706,GO:1903708,GO:1905114,GO:1990837,GO:2000026,GO:2000112,GO:2000113,GO:2001141,GO:2001233,GO:2001234,GO:2001236,GO:2001237	-	ko:K10802,ko:K11295	ko03410,ko04140,ko04217,map03410,map04140,map04217	-	-	-	ko00000,ko00001,ko03036,ko03400,ko04147	-	-	-	HMG_box,HMG_box_2
k59_1239642_1	706587.Desti_1825	7.44e-94	284.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2WJQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
k59_531911_1	87626.PTD2_05295	1.97e-22	99.0	COG2207@1|root,COG2207@2|Bacteria,1P4M5@1224|Proteobacteria,1SB0I@1236|Gammaproteobacteria,2Q5D8@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
k59_374253_1	717606.PaecuDRAFT_1764	1e-08	63.9	COG3210@1|root,COG3210@2|Bacteria,1V182@1239|Firmicutes,4HDU4@91061|Bacilli,26VIJ@186822|Paenibacillaceae	91061|Bacilli	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_20785_1	335543.Sfum_0862	3.69e-58	192.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria,2MQYJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_20785_2	1304885.AUEY01000002_gene369	1.38e-26	107.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42PEN@68525|delta/epsilon subdivisions,2WJ9F@28221|Deltaproteobacteria,2MIQU@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_1239678_1	1122604.JONR01000037_gene4267	9.38e-28	114.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1X3S1@135614|Xanthomonadales	135614|Xanthomonadales	H	receptor	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_1078294_1	911045.PSE_4811	1.79e-42	146.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2U75U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_1078294_2	1282876.BAOK01000001_gene1876	3.13e-18	84.7	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,4BPV8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	TRAP-type mannitol chloroaromatic compound transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
k59_218661_1	1288298.rosmuc_04063	2.35e-54	182.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,46P06@74030|Roseovarius	28211|Alphaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_961878_1	1304885.AUEY01000032_gene2011	9.45e-135	389.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2MI9R@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
k59_726750_1	1121405.dsmv_0049	1.96e-70	225.0	COG4191@1|root,COG4191@2|Bacteria,1MY12@1224|Proteobacteria,42PID@68525|delta/epsilon subdivisions,2WJVW@28221|Deltaproteobacteria,2MI1P@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
k59_1239737_1	1123367.C666_05845	1.14e-32	126.0	COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,2VJ40@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_803858_1	1120956.JHZK01000001_gene3368	2.41e-69	226.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TTBA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
k59_883232_1	1112214.AHIS01000083_gene3612	4.82e-33	130.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2TRVJ@28211|Alphaproteobacteria,2JZUZ@204457|Sphingomonadales	204457|Sphingomonadales	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
k59_138308_1	1232410.KI421428_gene1232	2.38e-42	140.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria,43SQ7@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein L23	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
k59_138308_2	1232410.KI421428_gene1233	1.29e-37	133.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,43TPD@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal Proteins L2, C-terminal domain	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
k59_1118433_1	44056.XP_009036948.1	1.32e-08	63.2	29QRV@1|root,2RX97@2759|Eukaryota	2759|Eukaryota	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	REJ,VCBS
k59_1078340_1	933262.AXAM01000017_gene3132	2.33e-10	66.2	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,2MI3T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
k59_803876_1	876044.IMCC3088_2595	1e-54	187.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNNJ@1236|Gammaproteobacteria,1J5CY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_803876_2	261292.Nit79A3_3262	1.4e-71	222.0	COG2738@1|root,COG2738@2|Bacteria,1RDJH@1224|Proteobacteria,2W832@28216|Betaproteobacteria,372AS@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
k59_374356_1	497965.Cyan7822_5247	1.94e-15	80.9	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3KGDE@43988|Cyanothece	1117|Cyanobacteria	T	PAS fold-4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_334655_1	518766.Rmar_1625	3.51e-48	170.0	COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,1FJSI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
k59_100633_1	1528106.JRJE01000006_gene996	5.12e-20	88.2	COG3806@1|root,COG3806@2|Bacteria,1RI6T@1224|Proteobacteria,2TVH9@28211|Alphaproteobacteria,2JSRN@204441|Rhodospirillales	204441|Rhodospirillales	T	ChrR Cupin-like domain	-	-	-	ko:K07167	-	-	-	-	ko00000	-	-	-	Cupin_7
k59_100633_2	1267005.KB911258_gene631	6.92e-26	101.0	COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,2U9G0@28211|Alphaproteobacteria,3N8TK@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	Sigma-70, region 4	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_569739_1	887062.HGR_05419	4.5e-54	181.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,2VI5F@28216|Betaproteobacteria,4ACT9@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
k59_726813_1	765910.MARPU_15835	1.22e-09	64.7	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
k59_374371_1	706587.Desti_1834	4e-118	359.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,2MQZU@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_491632_1	1121405.dsmv_3745	8.97e-83	260.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2WISS@28221|Deltaproteobacteria,2MHQH@213118|Desulfobacterales	28221|Deltaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
k59_883318_1	1121439.dsat_2182	3.49e-22	98.2	COG1150@1|root,COG2181@1|root,COG1150@2|Bacteria,COG2181@2|Bacteria,1R44N@1224|Proteobacteria,42NTE@68525|delta/epsilon subdivisions,2WJN8@28221|Deltaproteobacteria,2M8U1@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,Nitrate_red_gam
k59_647761_1	65497.JODV01000003_gene4807	1.82e-78	263.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4DXXG@85010|Pseudonocardiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_961984_1	338963.Pcar_3052	7.86e-85	272.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_803975_1	558884.JRGM01000136_gene1041	2.41e-16	79.3	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1Y3GM@135624|Aeromonadales	135624|Aeromonadales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
k59_491692_2	1286632.P278_03710	1.91e-47	155.0	COG2044@1|root,COG2044@2|Bacteria,4P2I4@976|Bacteroidetes,1I8SH@117743|Flavobacteriia	976|Bacteroidetes	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
k59_569816_1	1121878.AUGL01000002_gene2174	1.21e-27	115.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	iJN746.PP_4935	ABC_membrane,ABC_tran
k59_765519_1	640081.Dsui_0794	2.87e-98	306.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2VH5R@28216|Betaproteobacteria,2KUU7@206389|Rhodocyclales	206389|Rhodocyclales	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_844075_1	483219.LILAB_05630	3.93e-09	62.4	COG4784@1|root,COG4784@2|Bacteria,1QXTD@1224|Proteobacteria,42QR9@68525|delta/epsilon subdivisions,2WMY6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
k59_417403_1	765911.Thivi_0661	1.97e-98	301.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1WWXH@135613|Chromatiales	135613|Chromatiales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_687661_1	335543.Sfum_1278	2.65e-64	216.0	COG0427@1|root,COG0454@1|root,COG0427@2|Bacteria,COG0456@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MR2F@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	acetyl-CoA	-	-	-	ko:K18122,ko:K18288	ko00650,ko00660,ko01100,ko01200,map00650,map00660,map01100,map01200	-	R02407,R05336,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2142,iAF987.Gmet_3304	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
k59_218896_1	1286632.P278_08630	1.05e-06	53.1	COG1629@1|root,COG1629@2|Bacteria,4PM06@976|Bacteroidetes,1IJK3@117743|Flavobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
k59_452246_1	583355.Caka_1879	5.54e-97	301.0	28HMZ@1|root,2Z7WD@2|Bacteria,46TFX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_1197037_1	1121396.KB892913_gene117	1.1e-14	73.6	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,42N7M@68525|delta/epsilon subdivisions,2X5JU@28221|Deltaproteobacteria,2MPFA@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_374456_1	1265505.ATUG01000001_gene3897	1.19e-22	99.8	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42YJQ@68525|delta/epsilon subdivisions,2WTJP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
k59_59863_1	941449.dsx2_0029	8.87e-75	234.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,42NW9@68525|delta/epsilon subdivisions,2WJEJ@28221|Deltaproteobacteria,2M8R7@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
k59_844097_1	1123371.ATXH01000021_gene1130	6.88e-105	316.0	COG0055@1|root,COG0055@2|Bacteria,2GGRJ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_256939_2	1122604.JONR01000001_gene1829	9.14e-78	238.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1X34H@135614|Xanthomonadales	135614|Xanthomonadales	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
k59_21028_1	446468.Ndas_4080	1.29e-32	122.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EIFM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
k59_417459_1	2340.JV46_14330	6.03e-57	197.0	COG1269@1|root,COG1269@2|Bacteria,1R6B8@1224|Proteobacteria,1RYT3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
k59_181446_1	243164.DET0417	8.38e-49	164.0	COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi,34CW1@301297|Dehalococcoidia	301297|Dehalococcoidia	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
k59_612913_1	1535422.ND16A_0651	8.22e-35	138.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K03407,ko:K07678	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg
k59_63274_1	1307437.J139_02081	1.53e-71	243.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,2Q185@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Zn-dependent peptidases	ptrA	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
k59_537208_1	706587.Desti_4874	2.22e-73	236.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2MQ68@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_63279_1	1500897.JQNA01000001_gene5560	3.04e-09	57.0	COG3195@1|root,COG3195@2|Bacteria,1RH9S@1224|Proteobacteria,2VRV7@28216|Betaproteobacteria,1K3PK@119060|Burkholderiaceae	28216|Betaproteobacteria	S	OHCU decarboxylase	uraD	-	4.1.1.97	ko:K13485	ko00230,ko01100,map00230,map01100	M00546	R06604	RC01551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox
k59_63279_2	1336243.JAEA01000006_gene482	3.44e-76	241.0	COG0726@1|root,COG3195@1|root,COG0726@2|Bacteria,COG3195@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,1JR1F@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	PFAM polysaccharide deacetylase	pucL	GO:0000003,GO:0000272,GO:0003006,GO:0005575,GO:0005618,GO:0005619,GO:0005623,GO:0005631,GO:0005975,GO:0005976,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006037,GO:0006039,GO:0006040,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009272,GO:0009277,GO:0009653,GO:0009987,GO:0010383,GO:0010927,GO:0016043,GO:0016052,GO:0016998,GO:0017144,GO:0019953,GO:0022402,GO:0022411,GO:0022413,GO:0022414,GO:0022607,GO:0030154,GO:0030312,GO:0030435,GO:0030437,GO:0030476,GO:0031160,GO:0031505,GO:0032502,GO:0032505,GO:0032989,GO:0034218,GO:0034232,GO:0034293,GO:0042244,GO:0042546,GO:0042737,GO:0043170,GO:0043934,GO:0043935,GO:0044036,GO:0044085,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044277,GO:0044426,GO:0044462,GO:0044464,GO:0044703,GO:0045229,GO:0046348,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0070590,GO:0070591,GO:0070726,GO:0070910,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071852,GO:0071853,GO:0071854,GO:0071940,GO:0071944,GO:0071966,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903046	1.7.3.3,3.5.1.41	ko:K00365,ko:K01452	ko00230,ko00232,ko00520,ko01100,ko01120,map00230,map00232,map00520,map01100,map01120	M00546	R02106,R02333,R07981	RC00166,RC00300,RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox,Polysacc_deac_1
k59_422156_1	1224318.DT73_21560	4.78e-65	218.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	oligopeptidase	prlC	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_378069_1	243233.MCA1803	2.51e-37	132.0	COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,1S1VI@1236|Gammaproteobacteria,1XESX@135618|Methylococcales	135618|Methylococcales	Q	PFAM Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
k59_887035_1	1229487.AMYW01000006_gene562	3.23e-14	70.9	COG1943@1|root,COG1943@2|Bacteria,4NQTF@976|Bacteroidetes,1I1DP@117743|Flavobacteriia,2NW3U@237|Flavobacterium	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
k59_965775_2	713586.KB900536_gene1939	3.32e-40	137.0	COG0664@1|root,COG0664@2|Bacteria,1PDUV@1224|Proteobacteria,1SS1D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
k59_422182_1	1028801.RG1141_CH45130	1.43e-08	56.2	COG1877@1|root,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,2U9NF@28211|Alphaproteobacteria,4BCQC@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
k59_378100_1	1510531.JQJJ01000008_gene3920	1.83e-65	218.0	COG2943@1|root,COG2943@2|Bacteria,1MVXZ@1224|Proteobacteria,2TQU8@28211|Alphaproteobacteria,3K2N6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	ko:K03669	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.3.1.1	GT2	-	Glyco_trans_2_3,Glycos_transf_2
k59_104523_1	1313172.YM304_05020	8.33e-88	272.0	COG0520@1|root,COG0520@2|Bacteria,2GJA4@201174|Actinobacteria,4CNPT@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_104523_2	876044.IMCC3088_558	9.21e-09	56.6	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_141891_1	1033743.CAES01000064_gene4122	1.91e-08	55.8	COG3525@1|root,COG4223@1|root,COG3525@2|Bacteria,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	ko:K02040,ko:K20276,ko:K21449	ko02010,ko02020,ko02024,ko05152,map02010,map02020,map02024,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	1.B.40.2,3.A.1.7	-	-	DUF1631,DUF4838
k59_1010165_1	1121405.dsmv_2535	1.86e-70	228.0	COG0683@1|root,COG0683@2|Bacteria,1MYGR@1224|Proteobacteria,42YJT@68525|delta/epsilon subdivisions,2WU23@28221|Deltaproteobacteria,2MN85@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_847715_1	335543.Sfum_2345	2.01e-124	370.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MRAR@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_422214_1	981384.AEYW01000006_gene2798	5.48e-127	375.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,4NAYU@97050|Ruegeria	28211|Alphaproteobacteria	P	Sulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase,Sulfatase_C
k59_887074_1	765911.Thivi_4353	4.74e-26	106.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales	135613|Chromatiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_579095_1	998674.ATTE01000001_gene3690	3.09e-64	203.0	COG0678@1|root,COG0695@1|root,COG0678@2|Bacteria,COG0695@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,45ZZT@72273|Thiotrichales	72273|Thiotrichales	O	Glutaredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Glutaredoxin,Redoxin
k59_579095_2	911008.GLAD_02923	3.7e-18	84.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	gabD	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006553,GO:0006554,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019477,GO:0019752,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046440,GO:0047949,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_2847,iYL1228.KPN_00256	Aldedh
k59_579098_1	502025.Hoch_2172	9.37e-10	64.7	COG0515@1|root,COG3266@1|root,COG0515@2|Bacteria,COG3266@2|Bacteria,1PEIZ@1224|Proteobacteria,433VS@68525|delta/epsilon subdivisions,2X3Q2@28221|Deltaproteobacteria,2YWTJ@29|Myxococcales	2|Bacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1,3.4.16.4	ko:K01286,ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1565,Peptidase_S11,Pkinase,SPOR
k59_266281_1	765911.Thivi_4139	1.08e-92	289.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales	1224|Proteobacteria	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_461204_2	765911.Thivi_2442	8.47e-20	88.6	COG2204@1|root,COG2204@2|Bacteria,1R1SW@1224|Proteobacteria,1T59H@1236|Gammaproteobacteria,1WYKV@135613|Chromatiales	135613|Chromatiales	T	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
k59_1050184_1	859657.RPSI07_1272	1.04e-59	206.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,1JZNT@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_344260_1	1239962.C943_01612	1.72e-41	155.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,47JQH@768503|Cytophagia	976|Bacteroidetes	G	Alpha amylase, catalytic domain	amyA	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C
k59_892372_1	1450525.JATV01000004_gene247	1.7e-33	132.0	COG1574@1|root,COG1574@2|Bacteria,4P29B@976|Bacteroidetes,1I7KZ@117743|Flavobacteriia,2NYGC@237|Flavobacterium	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_735460_1	697282.Mettu_0354	1.36e-74	250.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Zn-dependent protease with chaperone function	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_1248605_1	1380387.JADM01000006_gene1139	1.25e-27	111.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,1RQQT@1236|Gammaproteobacteria,1XH3U@135619|Oceanospirillales	135619|Oceanospirillales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
k59_384702_1	765911.Thivi_4139	1.21e-63	212.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales	1224|Proteobacteria	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
k59_1050231_1	342610.Patl_2993	3.55e-42	157.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,2Q0XA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	HP	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_384715_1	9606.ENSP00000355467	9.5e-161	458.0	COG3268@1|root,KOG2733@2759|Eukaryota,38D2K@33154|Opisthokonta,3BE3X@33208|Metazoa,3CZIP@33213|Bilateria,486KW@7711|Chordata,496BV@7742|Vertebrata,3JBET@40674|Mammalia,35K2R@314146|Euarchontoglires,4ME1I@9443|Primates,4MSDX@9604|Hominidae	33208|Metazoa	S	oxidoreductase activity	SCCPDH	GO:0002576,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005811,GO:0006810,GO:0006887,GO:0007275,GO:0007423,GO:0007444,GO:0008150,GO:0009888,GO:0009987,GO:0012505,GO:0016192,GO:0022416,GO:0030141,GO:0030496,GO:0031091,GO:0031093,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032501,GO:0032502,GO:0032940,GO:0034774,GO:0035220,GO:0035295,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0046903,GO:0048513,GO:0048731,GO:0048856,GO:0051179,GO:0051234,GO:0060205,GO:0060429,GO:0070013,GO:0097708,GO:0099503	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
k59_428907_1	697282.Mettu_0021	2.84e-22	104.0	COG0834@1|root,COG2202@1|root,COG5001@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1SKBG@1236|Gammaproteobacteria,1XDV3@135618|Methylococcales	135618|Methylococcales	T	Diguanylate cyclase with PAS PAC sensor	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9,SBP_bac_3
k59_892432_1	1121406.JAEX01000005_gene2882	4.21e-31	119.0	COG3677@1|root,COG3677@2|Bacteria,1RFKN@1224|Proteobacteria,42RGK@68525|delta/epsilon subdivisions,2WNW7@28221|Deltaproteobacteria,2M7QY@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	ko:K07488	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_735520_2	1392486.JIAF01000004_gene854	3.2e-15	80.5	COG2985@1|root,COG2985@2|Bacteria,4NEBW@976|Bacteroidetes,2FMDF@200643|Bacteroidia	976|Bacteroidetes	P	TrkA C-terminal domain protein	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
k59_384759_1	714943.Mucpa_5701	1.2e-70	223.0	COG2801@1|root,COG2801@2|Bacteria,4NIBY@976|Bacteroidetes,1ITSB@117747|Sphingobacteriia	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_618763_1	1294143.H681_00300	4.12e-68	218.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048	Formyl_trans_C,Formyl_trans_N
k59_1166990_1	1049564.TevJSym_ar00380	3.33e-82	258.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1QYEW@1224|Proteobacteria,1T3PI@1236|Gammaproteobacteria,1JAK0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Pyr_redox_3
k59_1127608_1	766499.C357_12534	5.68e-29	115.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_1127608_2	685035.ADAE01000024_gene1866	1.15e-09	61.2	COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,2TRVE@28211|Alphaproteobacteria,2K0U1@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S9	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
k59_1050286_1	1167006.UWK_01225	1.01e-63	203.0	COG4849@1|root,COG4849@2|Bacteria,1RDHG@1224|Proteobacteria,42WAF@68525|delta/epsilon subdivisions,2WRPU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1050290_1	1144342.PMI40_01509	1.94e-51	180.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2VI60@28216|Betaproteobacteria,473N1@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_774855_1	754477.Q7C_1487	1.58e-48	169.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,460KP@72273|Thiotrichales	72273|Thiotrichales	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
k59_111272_1	1100720.ALKN01000045_gene111	1.87e-50	173.0	COG0590@1|root,COG0596@1|root,COG0590@2|Bacteria,COG0596@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,4A9VR@80864|Comamonadaceae	28216|Betaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
k59_1127646_1	1123514.KB905899_gene1162	2.22e-62	204.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amino Acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_266411_1	1260251.SPISAL_06495	5.8e-90	275.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,1WXNW@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_930630_1	61622.XP_010359741.1	1.34e-147	431.0	KOG4179@1|root,KOG4179@2759|Eukaryota,38BZB@33154|Opisthokonta,3BB9G@33208|Metazoa,3CT83@33213|Bilateria,47Z13@7711|Chordata,48YFR@7742|Vertebrata,3J1UB@40674|Mammalia,35DT1@314146|Euarchontoglires,4MI6H@9443|Primates,35W2Q@314294|Cercopithecoidea	33208|Metazoa	O	Collagen beta(1-O)galactosyltransferase 1	COLGALT1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0008150,GO:0008194,GO:0008378,GO:0012505,GO:0016740,GO:0016757,GO:0016758,GO:0031974,GO:0035250,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048518,GO:0048522,GO:0050211,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0065007,GO:0070013,GO:0140096,GO:1902903,GO:1902905,GO:1903053,GO:1903055,GO:1904026,GO:1904028	2.4.1.50	ko:K11703	ko00310,ko00514,map00310,map00514	-	R03380	RC00005,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT25	-	Glyco_tranf_2_4,Glyco_transf_25
k59_30060_1	1255043.TVNIR_2696	6.1e-81	250.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,1X02A@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
k59_1127664_1	1288826.MSNKSG1_05111	8.24e-91	290.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,463YR@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
k59_30083_1	335543.Sfum_4036	2.27e-35	135.0	COG0457@1|root,COG0457@2|Bacteria,1RCWA@1224|Proteobacteria,42RIH@68525|delta/epsilon subdivisions,2WNE2@28221|Deltaproteobacteria,2MS0S@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1014946_1	1049564.TevJSym_ca00030	5.08e-40	150.0	COG0419@1|root,COG1121@1|root,COG0419@2|Bacteria,COG1121@2|Bacteria	2|Bacteria	P	zinc-transporting ATPase activity	-	-	-	ko:K03546,ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.15.3,3.A.1.15.5	-	-	AAA_23,ABC_tran,SbcCD_C
k59_812480_1	765910.MARPU_10475	2.76e-26	111.0	COG1449@1|root,COG1449@2|Bacteria,1R3Z3@1224|Proteobacteria,1RNRC@1236|Gammaproteobacteria,1WVY7@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
k59_384877_1	94122.Shewana3_1659	1.58e-56	200.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2QA13@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrF	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1248765_1	1123274.KB899411_gene3027	2.54e-72	236.0	COG0737@1|root,COG0737@2|Bacteria,2J5Z0@203691|Spirochaetes	203691|Spirochaetes	F	Belongs to the 5'-nucleotidase family	ushA	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
k59_1050367_1	247634.GPB2148_417	3.23e-63	202.0	COG3439@1|root,COG3439@2|Bacteria,1NUU0@1224|Proteobacteria,1SN8G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
k59_618891_1	717231.Flexsi_0440	7.23e-62	202.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_344460_1	9606.ENSP00000216336	1.49e-156	441.0	COG5640@1|root,KOG3627@2759|Eukaryota,391KY@33154|Opisthokonta,3B9Q5@33208|Metazoa,3CRNT@33213|Bilateria,484YZ@7711|Chordata,494AT@7742|Vertebrata,3J1MX@40674|Mammalia,35ADU@314146|Euarchontoglires,4MDNI@9443|Primates,4MYTZ@9604|Hominidae	33208|Metazoa	O	Trypsin-like peptidase domain	CTSG	GO:0000323,GO:0001772,GO:0001775,GO:0001816,GO:0001906,GO:0001909,GO:0001990,GO:0001991,GO:0002002,GO:0002003,GO:0002228,GO:0002237,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002449,GO:0002682,GO:0002684,GO:0003008,GO:0003013,GO:0003044,GO:0003073,GO:0003081,GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005539,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006508,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006887,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007006,GO:0007154,GO:0007165,GO:0008015,GO:0008150,GO:0008152,GO:0008201,GO:0008217,GO:0008219,GO:0008233,GO:0008236,GO:0008626,GO:0009058,GO:0009059,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010467,GO:0010494,GO:0010638,GO:0010646,GO:0010647,GO:0010817,GO:0010821,GO:0010822,GO:0010941,GO:0010942,GO:0012501,GO:0012505,GO:0016020,GO:0016043,GO:0016192,GO:0016310,GO:0016485,GO:0016486,GO:0016787,GO:0017171,GO:0019538,GO:0019730,GO:0019731,GO:0022411,GO:0022617,GO:0023051,GO:0023052,GO:0023056,GO:0030141,GO:0030198,GO:0031347,GO:0031410,GO:0031640,GO:0031974,GO:0031982,GO:0031983,GO:0032101,GO:0032496,GO:0032501,GO:0032611,GO:0032612,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033043,GO:0033993,GO:0034641,GO:0034769,GO:0034774,GO:0035578,GO:0035770,GO:0035821,GO:0036211,GO:0036230,GO:0036464,GO:0040008,GO:0042089,GO:0042107,GO:0042119,GO:0042221,GO:0042222,GO:0042267,GO:0042445,GO:0042582,GO:0042742,GO:0042981,GO:0043062,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043412,GO:0043603,GO:0043900,GO:0043901,GO:0043903,GO:0044126,GO:0044130,GO:0044144,GO:0044146,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045055,GO:0045087,GO:0045321,GO:0045926,GO:0046902,GO:0046903,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048584,GO:0050720,GO:0050727,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050829,GO:0050830,GO:0050832,GO:0050886,GO:0050896,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051604,GO:0051702,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0060205,GO:0060341,GO:0061024,GO:0065007,GO:0065008,GO:0070011,GO:0070013,GO:0070201,GO:0070887,GO:0070942,GO:0070943,GO:0070944,GO:0070946,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071396,GO:0071704,GO:0071711,GO:0071840,GO:0071944,GO:0080134,GO:0090559,GO:0097190,GO:0097367,GO:0097708,GO:0098542,GO:0099503,GO:0140096,GO:1900739,GO:1900740,GO:1901028,GO:1901030,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1901700,GO:1901701,GO:1903747,GO:1903749,GO:1903827,GO:1903829,GO:1904951,GO:1905475,GO:1905477,GO:1990904,GO:2001233,GO:2001235	3.4.21.20,3.4.21.39,3.4.21.79	ko:K01319,ko:K01329,ko:K01353,ko:K09616	ko04080,ko04142,ko04210,ko04614,ko04650,ko04940,ko05146,ko05202,ko05320,ko05322,ko05330,ko05332,map04080,map04142,map04210,map04614,map04650,map04940,map05146,map05202,map05320,map05322,map05330,map05332	-	-	-	ko00000,ko00001,ko00536,ko01000,ko01002	-	-	-	Trypsin
k59_1206489_1	96561.Dole_0148	4.91e-41	153.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2MJNR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
k59_735660_1	309803.CTN_0219	6.6e-22	89.0	COG0080@1|root,COG0080@2|Bacteria,2GCUQ@200918|Thermotogae	200918|Thermotogae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
k59_735660_2	1123373.ATXI01000007_gene1668	6.39e-24	97.1	COG0081@1|root,COG0081@2|Bacteria,2GH9C@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
k59_1050405_1	1121918.ARWE01000001_gene42	1.81e-85	275.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,43BJY@68525|delta/epsilon subdivisions,2WIWD@28221|Deltaproteobacteria,43TK1@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	fdnG-2	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
k59_68936_1	1278307.KB906976_gene1564	9.03e-51	182.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RNWM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_1015013_1	1042377.AFPJ01000012_gene1410	2.1e-160	469.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,464DA@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Peptidase, M13	pepO	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
k59_305294_1	1380393.JHVP01000001_gene2522	0.000123	49.7	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4EU2H@85013|Frankiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigB	GO:0000988,GO:0000990,GO:0001666,GO:0002791,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009410,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032879,GO:0032880,GO:0036293,GO:0040007,GO:0042221,GO:0043175,GO:0043254,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051173,GO:0051223,GO:0051252,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0070063,GO:0070201,GO:0070482,GO:0071944,GO:0080090,GO:0090087,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
k59_188953_2	879212.DespoDRAFT_00212	1.67e-47	164.0	COG2048@1|root,COG2048@2|Bacteria,1RC7G@1224|Proteobacteria,43B85@68525|delta/epsilon subdivisions,2WMVG@28221|Deltaproteobacteria,2MJQR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	heterodisulfide reductase, subunit	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
k59_1251311_1	335543.Sfum_2566	1.39e-110	337.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MQ8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_933375_1	706587.Desti_2612	4.37e-95	295.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WJXY@28221|Deltaproteobacteria,2MRE3@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	succinate dehydrogenase or fumarate reductase, flavoprotein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
k59_621566_1	335543.Sfum_0314	7.96e-99	298.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria,2MRX0@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_699384_1	1123242.JH636434_gene3477	1.49e-21	98.2	COG2204@1|root,COG2204@2|Bacteria,2IXIQ@203682|Planctomycetes	203682|Planctomycetes	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_347232_1	565045.NOR51B_152	1.19e-53	190.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
k59_32829_1	1095769.CAHF01000006_gene1753	3.49e-32	120.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2VJUU@28216|Betaproteobacteria,475MD@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Sir2 family	cobB	-	-	-	-	-	-	-	-	-	-	-	SIR2
k59_581918_1	391615.ABSJ01000035_gene1009	2.67e-102	328.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1J4ZQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_308024_1	177437.HRM2_10730	5.2e-64	206.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MI0N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_621604_1	335543.Sfum_2600	4.39e-33	124.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_188988_1	1499967.BAYZ01000028_gene1365	9.73e-18	75.5	COG1278@1|root,COG1278@2|Bacteria,2NPXP@2323|unclassified Bacteria	2|Bacteria	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
k59_188988_3	368407.Memar_1256	2.38e-25	97.1	COG0724@1|root,arCOG06896@2157|Archaea	2157|Archaea	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
k59_503635_1	713586.KB900536_gene2146	8.63e-57	184.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1WWV1@135613|Chromatiales	135613|Chromatiales	L	PFAM Endonuclease Exonuclease phosphatase	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
k59_503635_2	1229205.BUPH_02886	6.25e-15	74.7	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria,1K0UB@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_387686_1	1144275.COCOR_00022	1.18e-50	179.0	COG2843@1|root,COG2843@2|Bacteria,1Q4SV@1224|Proteobacteria,42ZT3@68525|delta/epsilon subdivisions,2WV46@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	-	-	-	-	-	-	-	-	-	PGA_cap
k59_1052957_1	93220.LV28_22120	1.02e-45	164.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,1MUVM@1224|Proteobacteria,2VIHY@28216|Betaproteobacteria,1K26P@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
k59_231707_1	1403313.AXBR01000003_gene4017	6.53e-19	91.7	COG3547@1|root,COG3547@2|Bacteria,1V427@1239|Firmicutes,4HGY6@91061|Bacilli,1ZERT@1386|Bacillus	91061|Bacilli	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_150124_1	393595.ABO_1124	1.57e-98	299.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1XN3Q@135619|Oceanospirillales	135619|Oceanospirillales	P	Ammonium transporter	amtB1	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
k59_895516_1	1380355.JNIJ01000034_gene4331	2.11e-52	186.0	COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,2TTM4@28211|Alphaproteobacteria,3JW68@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Phospholipase D Active site motif	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2,SNARE_assoc
k59_581999_1	1218086.BBNB01000001_gene4040	5.37e-12	68.9	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,3WXV7@544|Citrobacter	1236|Gammaproteobacteria	F	Na+ dependent nucleoside transporter C-terminus	nupX	GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642	-	ko:K16324,ko:K16325	-	-	-	-	ko00000,ko02000	2.A.41.2.10,2.A.41.2.9	-	-	Nucleos_tra2_C,Nucleos_tra2_N
k59_581999_2	1231185.BAMP01000112_gene1553	2.1e-18	79.3	COG0662@1|root,COG0662@2|Bacteria,1N00P@1224|Proteobacteria,2UEIF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
k59_464090_1	477641.MODMU_1657	2.42e-36	132.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
k59_308129_1	1461694.ATO9_16045	1.94e-136	395.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria,2PDVF@252301|Oceanicola	28211|Alphaproteobacteria	I	acetyl-coa acetyltransferase	MA20_16305	-	-	-	-	-	-	-	-	-	-	-	-
k59_895569_1	756499.Desde_2050	2.31e-93	286.0	COG0407@1|root,COG0407@2|Bacteria,1TPQ6@1239|Firmicutes,24A8C@186801|Clostridia,261MG@186807|Peptococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
k59_855664_1	9478.XP_008047932.1	1.11e-117	347.0	KOG0420@1|root,KOG0420@2759|Eukaryota,38GRW@33154|Opisthokonta,3BGX6@33208|Metazoa,3CRHA@33213|Bilateria,47ZFU@7711|Chordata,48WTD@7742|Vertebrata,3J4S2@40674|Mammalia,35NIM@314146|Euarchontoglires,4M6WS@9443|Primates	33208|Metazoa	O	Belongs to the ubiquitin-conjugating enzyme family	UBE2M	GO:0003674,GO:0003824,GO:0004842,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008589,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0010941,GO:0010942,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019788,GO:0023051,GO:0023057,GO:0031974,GO:0031981,GO:0032446,GO:0036211,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043523,GO:0043525,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045116,GO:0045879,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0140096,GO:1901214,GO:1901216,GO:1901564	-	ko:K10579	ko04120,map04120	-	-	-	ko00000,ko00001,ko04121	-	-	-	UQ_con
k59_231763_1	9598.ENSPTRP00000046403	1.33e-155	447.0	KOG2615@1|root,KOG2615@2759|Eukaryota,38H2F@33154|Opisthokonta,3B9W5@33208|Metazoa,3CR7M@33213|Bilateria,481MZ@7711|Chordata,498BI@7742|Vertebrata,3J675@40674|Mammalia,35B8C@314146|Euarchontoglires,4METZ@9443|Primates,4MU0K@9604|Hominidae	33208|Metazoa	S	Major facilitator superfamily domain containing 10	MFSD10	GO:0000003,GO:0003006,GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005903,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0007276,GO:0007281,GO:0007292,GO:0008150,GO:0008493,GO:0008509,GO:0008514,GO:0009987,GO:0012506,GO:0015075,GO:0015238,GO:0015318,GO:0015665,GO:0015711,GO:0015850,GO:0015893,GO:0015904,GO:0016020,GO:0016021,GO:0019953,GO:0022412,GO:0022414,GO:0022857,GO:0030154,GO:0030659,GO:0031090,GO:0031224,GO:0031253,GO:0031410,GO:0031526,GO:0031982,GO:0032501,GO:0032502,GO:0032504,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0042995,GO:0043226,GO:0043227,GO:0043229,GO:0043252,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0048468,GO:0048477,GO:0048609,GO:0048856,GO:0048869,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071702,GO:0071944,GO:0097708,GO:0098590,GO:0098656,GO:0098862,GO:0120025,GO:0120038,GO:1901618	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_347301_1	1121405.dsmv_2388	3.4e-33	122.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2MHNA@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
k59_1090342_1	1211115.ALIQ01000049_gene3007	1.33e-19	92.4	COG2271@1|root,COG2271@2|Bacteria,1MVPS@1224|Proteobacteria,2TTHW@28211|Alphaproteobacteria,3NAG8@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_1170105_1	933262.AXAM01000018_gene973	3.37e-52	181.0	COG1388@1|root,COG3267@1|root,COG1388@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42QBH@68525|delta/epsilon subdivisions,2WISQ@28221|Deltaproteobacteria,2MIRA@213118|Desulfobacterales	28221|Deltaproteobacteria	U	AAA domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,Phage_tail_X
k59_1053032_1	395495.Lcho_4127	1.41e-48	163.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria,2VTRB@28216|Betaproteobacteria,1KNNN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
k59_1053032_2	864051.BurJ1DRAFT_4167	4.55e-41	140.0	COG3245@1|root,COG3245@2|Bacteria,1RG2V@1224|Proteobacteria,2VS0Q@28216|Betaproteobacteria,1KNH3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
k59_706654_1	518766.Rmar_1656	1.4e-47	174.0	COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1FIKN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	2.7.2.4,4.1.1.20	ko:K00928,ko:K12526	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00451,R00480	RC00002,RC00043,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_1098525_1	258594.RPA1400	2.4e-23	100.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2TU60@28211|Alphaproteobacteria,3JWHT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
k59_1098525_2	1485544.JQKP01000004_gene562	1.57e-83	259.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,44V37@713636|Nitrosomonadales	28216|Betaproteobacteria	H	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
k59_628328_1	1266909.AUAG01000004_gene2064	5.47e-53	179.0	COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,1S2EC@1236|Gammaproteobacteria,1X0UF@135613|Chromatiales	135613|Chromatiales	NU	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16
k59_1059263_1	237368.SCABRO_01831	3.21e-36	138.0	COG1215@1|root,COG1215@2|Bacteria,2IXX6@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2,PilZ
k59_941838_1	1380394.JADL01000003_gene5149	1.43e-40	145.0	COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,2TR35@28211|Alphaproteobacteria,2JW2W@204441|Rhodospirillales	204441|Rhodospirillales	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_1602_1	439235.Dalk_1444	5.59e-45	159.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,42NTH@68525|delta/epsilon subdivisions,2WJ8N@28221|Deltaproteobacteria,2MIMX@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_432411_1	373994.Riv7116_2163	2.74e-23	103.0	COG0438@1|root,COG2148@1|root,COG0438@2|Bacteria,COG2148@2|Bacteria,1GIW0@1117|Cyanobacteria,1HPPK@1161|Nostocales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
k59_79775_1	305900.GV64_15750	1.99e-109	321.0	COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,1RR22@1236|Gammaproteobacteria,1XNBP@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
k59_550019_1	1279017.AQYJ01000020_gene1286	1.14e-51	173.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,465VY@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
k59_550019_2	638303.Thal_1145	4.59e-28	106.0	COG4085@1|root,COG4085@2|Bacteria	2|Bacteria	S	PFAM nucleic acid binding, OB-fold, tRNA	yhcR	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	5_nucleotid_C,Gram_pos_anchor,Metallophos,PLDc_2,SNase
k59_1059295_2	1167006.UWK_01093	1.15e-87	265.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2MI23@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
k59_314861_1	96561.Dole_1932	9.76e-57	196.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria,2MHMP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
k59_354046_1	555779.Dthio_PD2849	2.19e-84	255.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria	1224|Proteobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_354046_2	1110502.TMO_1857	5.49e-06	49.3	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria,2JQH9@204441|Rhodospirillales	204441|Rhodospirillales	H	TonB-dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
k59_981011_1	1123229.AUBC01000039_gene3779	2.16e-70	222.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TQPQ@28211|Alphaproteobacteria,3JRXB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	hprA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
k59_119073_1	439292.Bsel_2351	2.77e-51	182.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli	91061|Bacilli	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_628393_1	439235.Dalk_3112	5.53e-132	388.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1RGKE@1224|Proteobacteria,42QI9@68525|delta/epsilon subdivisions,2WIV3@28221|Deltaproteobacteria,2MI92@213118|Desulfobacterales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,Lactamase_B_2
k59_275753_1	640081.Dsui_1099	4.86e-62	205.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,2KVQ1@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
k59_863532_1	314264.ROS217_13721	2.88e-12	67.8	COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2U874@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0760 Parvulin-like peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
k59_863532_2	1121878.AUGL01000021_gene2817	1.16e-34	129.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k59_1176845_4	9978.XP_004600107.1	9.31e-15	76.3	KOG1420@1|root,KOG1420@2759|Eukaryota,38CH0@33154|Opisthokonta,3BBT1@33208|Metazoa,3E4BF@33213|Bilateria,486FR@7711|Chordata,496VH@7742|Vertebrata,3J5XK@40674|Mammalia,35MJC@314146|Euarchontoglires	33208|Metazoa	P	Potassium channel, subfamily U, member	KCNU1	GO:0000003,GO:0003674,GO:0005215,GO:0005216,GO:0005227,GO:0005244,GO:0005249,GO:0005261,GO:0005267,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0007338,GO:0008037,GO:0008076,GO:0008150,GO:0008324,GO:0009566,GO:0009987,GO:0009988,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015269,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0019953,GO:0022414,GO:0022803,GO:0022832,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0031647,GO:0032991,GO:0034220,GO:0034702,GO:0034703,GO:0034705,GO:0035036,GO:0044425,GO:0044459,GO:0044464,GO:0044703,GO:0046873,GO:0050821,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0060072,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:1902495,GO:1990351	-	ko:K05274	ko04022,ko04270,ko04911,map04022,map04270,map04911	-	-	-	ko00000,ko00001,ko04040	1.A.1.3.5	-	-	BK_channel_a,Ion_trans,Ion_trans_2
k59_824384_1	314278.NB231_00235	7.52e-116	342.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1X0BB@135613|Chromatiales	135613|Chromatiales	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
k59_40572_2	675815.VOA_002728	1.77e-11	65.1	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,1XSD4@135623|Vibrionales	135623|Vibrionales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
k59_471682_1	1237149.C900_00028	2.14e-68	228.0	COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,47KAN@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
k59_510801_1	177437.HRM2_39480	1.14e-10	67.0	COG3385@1|root,COG3385@2|Bacteria,1RM2A@1224|Proteobacteria,42WE3@68525|delta/epsilon subdivisions,2X6QW@28221|Deltaproteobacteria,2MN97@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_1098623_1	566466.NOR53_2673	9.62e-39	144.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1J849@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	clsC	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_1176876_1	880073.Calab_0402	2.23e-39	134.0	2EKSD@1|root,33EG5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1176876_2	330779.Saci_1096	6.68e-17	80.5	COG4294@1|root,arCOG01898@2157|Archaea	2157|Archaea	L	UV-endonuclease UvdE	uvsE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
k59_550130_1	690850.Desaf_0076	1.76e-50	178.0	COG2208@1|root,COG2208@2|Bacteria,1R7WZ@1224|Proteobacteria,42Q3R@68525|delta/epsilon subdivisions,2WM5A@28221|Deltaproteobacteria,2MADW@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	SMART Protein phosphatase	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SSF,SpoIIE
k59_119141_1	566466.NOR53_3566	2.67e-85	265.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria,1J7W3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_706822_2	321332.CYB_2518	2.99e-45	155.0	COG3001@1|root,COG3001@2|Bacteria,1G040@1117|Cyanobacteria,1GZY8@1129|Synechococcus	1117|Cyanobacteria	G	COG3001 Fructosamine-3-kinase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
k59_354158_1	335543.Sfum_1997	3.83e-16	77.8	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,42PBW@68525|delta/epsilon subdivisions,2WJV5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
k59_863612_1	1232410.KI421427_gene1269	6.43e-42	152.0	COG2414@1|root,COG2414@2|Bacteria,1NSMY@1224|Proteobacteria,42YB0@68525|delta/epsilon subdivisions,2WUEE@28221|Deltaproteobacteria,43TWG@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AFOR_C,AFOR_N
k59_865868_1	1318628.MARLIPOL_10871	0.000554	43.9	COG2199@1|root,COG2199@2|Bacteria,1NV1F@1224|Proteobacteria,1T1UD@1236|Gammaproteobacteria,46A7X@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,PAS_9,dCache_1
k59_865868_2	187272.Mlg_2821	1.81e-41	146.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,1RMDF@1236|Gammaproteobacteria,1WWFW@135613|Chromatiales	135613|Chromatiales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
k59_42924_1	338963.Pcar_2679	5.68e-46	166.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria,43RZN@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	zinc finger	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
k59_1100944_1	1192034.CAP_8277	3.3e-39	149.0	COG3266@1|root,COG3266@2|Bacteria,1QZBM@1224|Proteobacteria,42TG7@68525|delta/epsilon subdivisions,2WQPM@28221|Deltaproteobacteria,2Z3I2@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
k59_944352_1	1232410.KI421412_gene396	2.91e-94	288.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2WJB8@28221|Deltaproteobacteria,43S6R@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Aldehyde dehydrogenase family	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_82452_1	1120934.KB894426_gene3520	1.56e-06	52.4	COG1309@1|root,COG1309@2|Bacteria,2GJZT@201174|Actinobacteria,4E5F4@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_1101003_1	644282.Deba_2993	1.83e-78	260.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_42973_1	396588.Tgr7_1857	6.2e-79	256.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1WXY0@135613|Chromatiales	135613|Chromatiales	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
k59_160747_2	134676.ACPL_5570	4.24e-12	68.6	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
k59_42978_2	225937.HP15_585	4.09e-74	230.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,4655B@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009898,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
k59_356569_1	706587.Desti_1206	1.3e-107	325.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2MQXU@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
k59_787599_1	593105.S7A_11505	1.65e-12	72.8	COG3515@1|root,COG3515@2|Bacteria,1NK35@1224|Proteobacteria,1RQHZ@1236|Gammaproteobacteria,3VZCZ@53335|Pantoea	1236|Gammaproteobacteria	S	type VI secretion-associated protein, ImpA family	-	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N
k59_4088_1	2340.JV46_05690	3.47e-158	452.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria,1JBRQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	L COG2826 Transposase and inactivated derivatives, IS30 family	insI	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k59_1140003_1	933262.AXAM01000006_gene1870	1.67e-93	284.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
k59_317208_1	675817.VDA_002947	1.21e-09	63.2	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1XSH3@135623|Vibrionales	135623|Vibrionales	MU	general secretion pathway protein	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1,T2SSB
k59_591767_1	909663.KI867149_gene3363	1.94e-21	92.4	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,42M9F@68525|delta/epsilon subdivisions,2WJNB@28221|Deltaproteobacteria,2MQ6U@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_591767_2	933262.AXAM01000028_gene3307	7.51e-61	198.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,2MI3S@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_474044_1	589865.DaAHT2_1400	5.74e-79	263.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MI79@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_591769_1	449447.MAE_58430	2.19e-85	262.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1G3YK@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
k59_1140016_1	42256.RradSPS_2442	1.92e-23	96.7	COG1028@1|root,COG1028@2|Bacteria,2I4BS@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_1140016_2	643562.Daes_1302	1.9e-07	49.7	2AHZB@1|root,318CN@2|Bacteria,1Q067@1224|Proteobacteria,43EKF@68525|delta/epsilon subdivisions,2X0Z8@28221|Deltaproteobacteria,2MDU3@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
k59_1179583_1	1122197.ATWI01000009_gene1910	4.13e-06	47.8	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,464SF@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG2217 Cation transport ATPase	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
k59_1179583_2	1033802.SSPSH_002855	2.57e-15	70.1	COG3197@1|root,COG3197@2|Bacteria	2|Bacteria	P	Cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
k59_1179583_3	1415780.JPOG01000001_gene2435	5.54e-12	67.8	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1X66I@135614|Xanthomonadales	135614|Xanthomonadales	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
k59_121566_1	880072.Desac_0177	5.13e-69	221.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,42Q9D@68525|delta/epsilon subdivisions,2WK21@28221|Deltaproteobacteria,2MQ4M@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
k59_238961_1	1177154.Y5S_01795	1.04e-41	150.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria,1XKGZ@135619|Oceanospirillales	135619|Oceanospirillales	L	Domain of unknown function (DUF4372)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
k59_160816_1	42565.FP66_13530	3.24e-21	97.1	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1XHTS@135619|Oceanospirillales	135619|Oceanospirillales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metX	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
k59_317252_1	1232437.KL662020_gene705	8.36e-56	189.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_160822_1	330084.JNYZ01000010_gene6823	3.82e-11	69.3	COG3899@1|root,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4E9F4@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,DZR,GerE,Guanylate_cyc,Trans_reg_C
k59_552528_1	292415.Tbd_2359	5.94e-64	209.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2VJ89@28216|Betaproteobacteria,1KRE8@119069|Hydrogenophilales	119069|Hydrogenophilales	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
k59_865984_1	1042377.AFPJ01000054_gene1686	2.75e-30	120.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,469KU@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_121617_1	342610.Patl_0618	1.46e-43	156.0	COG0845@1|root,COG0845@2|Bacteria,1MVFN@1224|Proteobacteria,1RNN6@1236|Gammaproteobacteria,2Q11Z@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18990	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_474126_1	1217718.ALOU01000007_gene1259	6.22e-86	265.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2VM5U@28216|Betaproteobacteria,1KF02@119060|Burkholderiaceae	28216|Betaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
k59_787692_1	566466.NOR53_2559	1.58e-77	248.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_239027_1	521460.Athe_1507	1.01e-42	154.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,42EK2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
k59_1179701_1	882.DVU_0646	1.28e-34	129.0	COG2243@1|root,COG2243@2|Bacteria,1MV3G@1224|Proteobacteria,42MGC@68525|delta/epsilon subdivisions,2WM51@28221|Deltaproteobacteria,2MA4W@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cbiL	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0482	TP_methylase
k59_160887_1	1121921.KB898707_gene1257	9.48e-39	138.0	COG3637@1|root,COG3637@2|Bacteria,1RHVI@1224|Proteobacteria,1S6UY@1236|Gammaproteobacteria,2PP0E@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA_membrane
k59_160887_2	583355.Caka_2912	8.39e-49	169.0	COG3303@1|root,COG3303@2|Bacteria,46UP1@74201|Verrucomicrobia,3K7Z3@414999|Opitutae	414999|Opitutae	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
k59_866016_2	1249627.D779_0038	1.81e-87	268.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria,1WWR2@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_552574_1	1123072.AUDH01000019_gene2213	1.11e-60	194.0	COG1028@1|root,COG1028@2|Bacteria,1PEWK@1224|Proteobacteria,2TV4E@28211|Alphaproteobacteria,2JV22@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
k59_239038_1	414684.RC1_1428	3.28e-32	119.0	COG1695@1|root,COG1695@2|Bacteria,1N33P@1224|Proteobacteria,2U9ZC@28211|Alphaproteobacteria,2JTEX@204441|Rhodospirillales	204441|Rhodospirillales	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
k59_552581_1	583355.Caka_0770	5.2e-54	183.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Glycos_transf_2
k59_866022_1	911045.PSE_1374	1.94e-62	206.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2TRUQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YeeE YedE family protein	soxT	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
k59_826900_1	644282.Deba_2183	7.5e-62	213.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_1023113_1	29073.XP_008708225.1	4e-202	560.0	COG0052@1|root,KOG0830@2759|Eukaryota,38E10@33154|Opisthokonta,3BAV4@33208|Metazoa,3CSAI@33213|Bilateria,489EH@7711|Chordata,490SZ@7742|Vertebrata,3J28J@40674|Mammalia,3ES4E@33554|Carnivora	33208|Metazoa	J	Required for the assembly and or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits	RPSA	GO:0000028,GO:0000184,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0000956,GO:0002181,GO:0003674,GO:0003735,GO:0005055,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005604,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006403,GO:0006405,GO:0006407,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006611,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006996,GO:0007155,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009888,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015931,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0019222,GO:0019439,GO:0019538,GO:0022607,GO:0022610,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030154,GO:0030490,GO:0030684,GO:0030686,GO:0030855,GO:0031012,GO:0031123,GO:0031125,GO:0031503,GO:0031974,GO:0031981,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034470,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0036477,GO:0042254,GO:0042255,GO:0042274,GO:0042886,GO:0043021,GO:0043022,GO:0043025,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043236,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044297,GO:0044391,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0048856,GO:0048869,GO:0050657,GO:0050658,GO:0050789,GO:0050840,GO:0051029,GO:0051168,GO:0051169,GO:0051179,GO:0051234,GO:0051236,GO:0051641,GO:0051649,GO:0060255,GO:0060429,GO:0062023,GO:0065003,GO:0065007,GO:0070013,GO:0070727,GO:0070925,GO:0070972,GO:0071166,GO:0071426,GO:0071428,GO:0071702,GO:0071704,GO:0071705,GO:0071826,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097064,GO:0097458,GO:0098609,GO:0098631,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02998,ko:K21848	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04131	9.A.19.1	-	-	40S_SA_C,Ribosomal_S2
k59_1101175_1	706587.Desti_2954	2.31e-56	193.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2MR2Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
k59_944520_1	1547437.LL06_26180	2.2e-104	305.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2VBH8@28211|Alphaproteobacteria,43P72@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
k59_944520_2	1101192.KB910516_gene2989	3.73e-25	100.0	COG3415@1|root,COG3415@2|Bacteria,1NA4C@1224|Proteobacteria,2UIPD@28211|Alphaproteobacteria,1JZAN@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23
k59_317368_1	266835.14024197	3.28e-96	302.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16
k59_474205_1	1535422.ND16A_2145	3.2e-09	63.2	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,2Q7V0@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_8,Trans_reg_C
k59_983852_1	177437.HRM2_04620	1.58e-59	205.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2MI13@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
k59_748469_1	96561.Dole_1094	4.67e-14	72.0	COG0471@1|root,COG0490@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2MMR4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_748469_2	1144275.COCOR_06404	2.69e-12	67.8	COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
k59_43177_2	13616.ENSMODP00000040074	7e-10	59.3	COG1005@1|root,KOG4770@2759|Eukaryota	2759|Eukaryota	C	NADH dehydrogenase (quinone) activity	ND1	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010033,GO:0010257,GO:0014070,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030425,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032981,GO:0032991,GO:0033108,GO:0033194,GO:0034622,GO:0034641,GO:0036477,GO:0042221,GO:0042493,GO:0042773,GO:0042775,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0050896,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0097447,GO:0097458,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0120025,GO:0120038,GO:1901135,GO:1901360,GO:1901564,GO:1901700,GO:1902494,GO:1990204	1.6.5.3	ko:K03878,ko:K04257	ko00190,ko01100,ko04714,ko04723,ko04740,ko05012,map00190,map01100,map04714,map04723,map04740,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029,ko04030	3.D.1.6	-	-	NADHdh
k59_670225_1	65393.PCC7424_4272	6.83e-40	152.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria,3KGWK@43988|Cyanothece	1117|Cyanobacteria	C	CoA-binding domain protein	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
k59_591926_1	1123073.KB899242_gene1152	2.18e-64	209.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1X2XI@135614|Xanthomonadales	135614|Xanthomonadales	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_1218601_1	933262.AXAM01000024_gene741	2.54e-111	328.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,42M16@68525|delta/epsilon subdivisions,2WM0V@28221|Deltaproteobacteria,2MKMA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Amino acid kinase family	cpkA	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
k59_1179812_1	335543.Sfum_2852	2.52e-42	152.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMQE@28221|Deltaproteobacteria,2MRRD@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
k59_1101224_1	1201293.AKXQ01000002_gene1700	1.23e-74	234.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Lytic murein transglycosylase	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
k59_944567_1	107636.JQNK01000008_gene3998	2.97e-20	85.5	2D1MV@1|root,32TAZ@2|Bacteria,1N45A@1224|Proteobacteria,2UEJT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage protein (N4 Gp49/phage Sf6 gene 66) family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_gp49_66
k59_631052_2	323848.Nmul_A0006	8.45e-31	117.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,371NG@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
k59_905190_1	439235.Dalk_1317	2.32e-47	166.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,42Q03@68525|delta/epsilon subdivisions,2WMFQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_43222_1	106370.Francci3_2318	5.42e-42	152.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
k59_787848_1	335543.Sfum_2348	9.82e-94	286.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,42MCA@68525|delta/epsilon subdivisions,2WJVX@28221|Deltaproteobacteria,2MQT9@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
k59_670287_1	1304885.AUEY01000001_gene3191	3.56e-51	181.0	COG0484@1|root,COG0484@2|Bacteria,1R72H@1224|Proteobacteria,42NCE@68525|delta/epsilon subdivisions,2WKDN@28221|Deltaproteobacteria,2MKP5@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
k59_983949_1	1267211.KI669560_gene2082	2.24e-25	108.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PA,PD40,PDZ_2,Peptidase_M28
k59_1101281_2	1298593.TOL_3419	5.19e-08	57.8	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RUFU@1236|Gammaproteobacteria,1XJBV@135619|Oceanospirillales	135619|Oceanospirillales	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_317475_1	1122604.JONR01000033_gene31	2.1e-84	258.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1X42V@135614|Xanthomonadales	135614|Xanthomonadales	H	polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
k59_43279_1	906968.Trebr_1906	1.83e-05	52.0	COG0815@1|root,COG0815@2|Bacteria,2J60T@203691|Spirochaetes	203691|Spirochaetes	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
k59_356964_1	1244531.CIG1485E_0458	7.31e-18	83.6	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2YNAK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	amino acid abc transporter	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_82832_1	2340.JV46_18690	4.26e-37	129.0	arCOG05193@1|root,2ZZSG@2|Bacteria,1REJB@1224|Proteobacteria,1SQYC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_555883_2	857293.CAAU_2573	3.85e-25	98.2	2DMJP@1|root,32S0N@2|Bacteria,1V766@1239|Firmicutes,24K8E@186801|Clostridia,36K7I@31979|Clostridiaceae	186801|Clostridia	S	D-ornithine 4,5-aminomutase alpha-subunit	oraS	-	5.4.3.5	ko:K17899	ko00472,map00472	-	R02461	RC00719	ko00000,ko00001,ko01000	-	-	-	OAM_alpha
k59_751773_1	10160.XP_004622986.1	4.45e-225	644.0	KOG1076@1|root,KOG1076@2759|Eukaryota,38EZF@33154|Opisthokonta,3BBRU@33208|Metazoa,3CRH9@33213|Bilateria,4845X@7711|Chordata,48YVK@7742|Vertebrata,3J5TD@40674|Mammalia,35KZ6@314146|Euarchontoglires,4PSEK@9989|Rodentia	33208|Metazoa	J	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2 GTP methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression	EIF3C	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005852,GO:0006412,GO:0006413,GO:0006417,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031369,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065009,GO:0071541,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902415,GO:1902416,GO:1905214,GO:1905216,GO:2000112	-	ko:K03252	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	PCI,eIF-3c_N
k59_1065287_1	709986.Deima_1164	1.87e-50	177.0	COG0170@1|root,COG0170@2|Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	-	-	2.7.1.182,2.7.7.41	ko:K00981,ko:K18678	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799,R10659	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1,DUF92
k59_1026427_1	706587.Desti_2519	4.1e-136	400.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,42M2C@68525|delta/epsilon subdivisions,2WIVE@28221|Deltaproteobacteria,2MQT5@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
k59_281538_1	1121033.AUCF01000036_gene3984	3.58e-38	138.0	COG2267@1|root,COG2267@2|Bacteria,1QUMY@1224|Proteobacteria,2UEAV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_360460_1	670307.HYPDE_30408	4.37e-50	167.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2TRD9@28211|Alphaproteobacteria,3N63G@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_1104594_1	926549.KI421517_gene3817	9.83e-75	244.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,47MEE@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
k59_555911_1	1267005.KB911255_gene3012	1.3e-40	143.0	COG4111@1|root,COG4111@2|Bacteria,1MXHA@1224|Proteobacteria,2TQQU@28211|Alphaproteobacteria,3N7IW@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	F	belongs to the nudix hydrolase family	MA20_42130	-	-	-	-	-	-	-	-	-	-	-	-
k59_1143551_1	765911.Thivi_1205	1.12e-51	184.0	COG0784@1|root,COG0834@1|root,COG2198@1|root,COG4251@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2198@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria,1X2QI@135613|Chromatiales	135613|Chromatiales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
k59_46280_1	1500894.JQNN01000001_gene4183	7.58e-46	164.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2VH5R@28216|Betaproteobacteria,472DD@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	protease with the C-terminal PDZ	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
k59_46280_2	99598.Cal7507_5398	1.9e-08	55.1	COG1834@1|root,COG1915@1|root,COG1834@2|Bacteria,COG1915@2|Bacteria,1G2AU@1117|Cyanobacteria,1HK7P@1161|Nostocales	1117|Cyanobacteria	E	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf,Saccharop_dh_N
k59_1065307_1	61622.XP_010353779.1	2.18e-155	436.0	COG0652@1|root,KOG0880@2759|Eukaryota,38FKT@33154|Opisthokonta,3BCX1@33208|Metazoa,3CS7W@33213|Bilateria,485X0@7711|Chordata,490DE@7742|Vertebrata,3JBR9@40674|Mammalia,359JE@314146|Euarchontoglires,4M5S1@9443|Primates,36283@314294|Cercopithecoidea	33208|Metazoa	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	PPIB	GO:0000413,GO:0001501,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005788,GO:0005790,GO:0006457,GO:0006464,GO:0006807,GO:0006810,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0012505,GO:0016018,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0019899,GO:0031647,GO:0031974,GO:0032501,GO:0032502,GO:0032991,GO:0033218,GO:0034663,GO:0035821,GO:0036211,GO:0040008,GO:0040014,GO:0040018,GO:0042277,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043900,GO:0043902,GO:0043903,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044788,GO:0044794,GO:0044827,GO:0044829,GO:0044877,GO:0045069,GO:0045070,GO:0045927,GO:0046907,GO:0048471,GO:0048513,GO:0048518,GO:0048524,GO:0048638,GO:0048639,GO:0048731,GO:0048856,GO:0050789,GO:0050792,GO:0050793,GO:0050821,GO:0051082,GO:0051094,GO:0051169,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051702,GO:0051704,GO:0051817,GO:0051851,GO:0060348,GO:0061077,GO:0065007,GO:0065008,GO:0070013,GO:0070063,GO:0071704,GO:0140096,GO:1901564,GO:1903900,GO:1903902	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
k59_947697_1	1502851.FG93_01573	1.27e-48	177.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,3JRIC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
k59_791005_1	1288484.APCS01000098_gene1340	6.47e-56	189.0	COG0477@1|root,COG2814@2|Bacteria,1WJQ8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
k59_634558_1	384676.PSEEN1767	4.47e-55	195.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_830031_1	43179.ENSSTOP00000006187	7.57e-121	345.0	KOG1727@1|root,KOG1727@2759|Eukaryota,3A0TB@33154|Opisthokonta,3BHKW@33208|Metazoa,3D0AV@33213|Bilateria,484AC@7711|Chordata,48Z25@7742|Vertebrata,3J8AK@40674|Mammalia,35I2W@314146|Euarchontoglires,4Q0A7@9989|Rodentia	33208|Metazoa	DZ	Translationally-controlled tumor	TPT1	GO:0000003,GO:0000075,GO:0000077,GO:0000278,GO:0001932,GO:0001934,GO:0003674,GO:0005085,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005700,GO:0005737,GO:0005768,GO:0005770,GO:0005771,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006974,GO:0007049,GO:0007093,GO:0007095,GO:0007276,GO:0007283,GO:0007346,GO:0008017,GO:0008092,GO:0008134,GO:0008150,GO:0008152,GO:0008283,GO:0008361,GO:0009314,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010212,GO:0010332,GO:0010389,GO:0010562,GO:0010564,GO:0010604,GO:0010638,GO:0010646,GO:0010648,GO:0010941,GO:0010948,GO:0010972,GO:0012505,GO:0015631,GO:0016043,GO:0019220,GO:0019222,GO:0019725,GO:0019827,GO:0019899,GO:0019953,GO:0022402,GO:0022414,GO:0023051,GO:0023057,GO:0030001,GO:0030003,GO:0030154,GO:0031056,GO:0031058,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031410,GO:0031570,GO:0031572,GO:0031573,GO:0031974,GO:0031981,GO:0031982,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0033043,GO:0033044,GO:0033127,GO:0033129,GO:0033554,GO:0034641,GO:0040008,GO:0040014,GO:0040018,GO:0042325,GO:0042327,GO:0042592,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044773,GO:0044774,GO:0044818,GO:0045595,GO:0045786,GO:0045793,GO:0045927,GO:0045930,GO:0045937,GO:0046483,GO:0046872,GO:0048232,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048609,GO:0048638,GO:0048639,GO:0048869,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051020,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0060255,GO:0060548,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070838,GO:0071214,GO:0071478,GO:0071479,GO:0071480,GO:0071704,GO:0071840,GO:0072503,GO:0072507,GO:0072511,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0090304,GO:0097708,GO:0098727,GO:0098771,GO:0098772,GO:0104004,GO:1901360,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902229,GO:1902230,GO:1902275,GO:1902531,GO:1902532,GO:1902749,GO:1902750,GO:1903047,GO:1905269,GO:2000383,GO:2000384,GO:2000736,GO:2001020,GO:2001021,GO:2001233,GO:2001234,GO:2001242,GO:2001243,GO:2001252	-	ko:K20301	-	-	-	-	ko00000,ko04131	-	-	-	TCTP
k59_1222177_1	755732.Fluta_2122	1.22e-37	139.0	COG0182@1|root,COG0182@2|Bacteria,4NETC@976|Bacteroidetes	976|Bacteroidetes	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
k59_1222177_2	13037.EHJ73977	3.81e-16	76.6	COG0190@1|root,KOG0089@2759|Eukaryota,38DGG@33154|Opisthokonta,3B98B@33208|Metazoa,3CT16@33213|Bilateria,41TQN@6656|Arthropoda,3SHF7@50557|Insecta,443TG@7088|Lepidoptera	33208|Metazoa	H	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain	Nmdmc	GO:0000287,GO:0003674,GO:0003824,GO:0004477,GO:0004487,GO:0004488,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009256,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042301,GO:0042558,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564	1.1.1.79,1.1.1.81,1.5.1.15,3.5.4.9	ko:K00049,ko:K13403	ko00260,ko00620,ko00630,ko00670,ko01100,ko01110,ko01120,map00260,map00620,map00630,map00670,map01100,map01110,map01120	M00141	R00465,R01218,R01388,R01392,R01655,R02527	RC00031,RC00042,RC00202,RC00578,RC00670	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
k59_203121_1	314287.GB2207_04084	2.63e-64	209.0	COG1196@1|root,COG1196@2|Bacteria,1R4BS@1224|Proteobacteria,1S13B@1236|Gammaproteobacteria,1J7UD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	von Willebrand factor (VWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
k59_7616_1	1046724.KB889917_gene244	6.75e-140	434.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,464QF@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_125287_1	1120956.JHZK01000007_gene2920	5.27e-95	293.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,1JPBE@119043|Rhodobiaceae	28211|Alphaproteobacteria	M	Mechanosensitive ion channel	MA20_40450	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_908419_1	1384054.N790_14300	9.44e-148	446.0	COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria,1X5QP@135614|Xanthomonadales	135614|Xanthomonadales	P	receptor	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	Plug,TonB_dep_Rec
k59_281619_1	1121406.JAEX01000001_gene18	4.1e-39	139.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,42M3F@68525|delta/epsilon subdivisions,2WJ32@28221|Deltaproteobacteria,2M7V3@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
k59_281619_2	1190606.AJYG01000029_gene2948	7.03e-20	86.7	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,1XTS5@135623|Vibrionales	135623|Vibrionales	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
k59_477621_1	1122216.AUHW01000007_gene1505	1.39e-55	186.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H28A@909932|Negativicutes	909932|Negativicutes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
k59_46326_1	396588.Tgr7_1431	1.98e-24	99.8	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1SASJ@1236|Gammaproteobacteria,1WY3C@135613|Chromatiales	135613|Chromatiales	S	Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k59_555966_1	595536.ADVE02000001_gene3062	5.26e-75	238.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_673610_1	1121439.dsat_0638	1.41e-94	282.0	COG0437@1|root,COG0437@2|Bacteria,1RCHX@1224|Proteobacteria,42S80@68525|delta/epsilon subdivisions,2X5D4@28221|Deltaproteobacteria,2MEPC@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
k59_673610_2	713587.THITH_16735	1.24e-29	118.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_164354_1	1120983.KB894574_gene979	2.71e-121	357.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TSBN@28211|Alphaproteobacteria,1JNFI@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
k59_438343_1	765912.Thimo_2526	1.34e-107	316.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1WWM1@135613|Chromatiales	135613|Chromatiales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
k59_556007_1	1046714.AMRX01000006_gene2716	1.52e-15	81.3	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,46524@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG0665 Glycine D-amino acid oxidases (deaminating)	dadA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0008718,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009324,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019478,GO:0019480,GO:0019752,GO:0032991,GO:0042851,GO:0042853,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055114,GO:0055130,GO:0071704,GO:0071944,GO:0098796,GO:0098797,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_1883,iSFV_1184.SFV_1196,iSF_1195.SF1178,iSFxv_1172.SFxv_1352,iS_1188.S1266,iUMNK88_1353.UMNK88_1502,iYL1228.KPN_02309	DAO
k59_517154_1	1006004.GBAG_0863	0.000932	47.4	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	mechanosensitive ion channel	kefA	GO:0005575,GO:0005623,GO:0005886,GO:0006884,GO:0008150,GO:0008361,GO:0009987,GO:0009992,GO:0016020,GO:0016043,GO:0019725,GO:0030104,GO:0032535,GO:0042592,GO:0044464,GO:0048878,GO:0055082,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K05802,ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.1.2,1.A.23.1.3	-	-	MS_channel,MscS_TM,MscS_porin
k59_203202_1	1414720.CBYM010000011_gene2682	8.64e-57	199.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,36E0I@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
k59_46378_1	797114.C475_04401	5.14e-62	216.0	COG0471@1|root,arCOG00237@2157|Archaea,2XSW7@28890|Euryarchaeota,23SDG@183963|Halobacteria	183963|Halobacteria	P	COG0471 Di- and tricarboxylate transporters	nso	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
k59_86530_1	1116472.MGMO_223c00090	2.22e-20	92.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1XDZC@135618|Methylococcales	135618|Methylococcales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_987408_1	243233.MCA0565	7.98e-27	114.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1XE41@135618|Methylococcales	135618|Methylococcales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
k59_634661_1	1415780.JPOG01000001_gene2738	6.82e-52	171.0	COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,1S449@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM cytoplasmic chaperone TorD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
k59_830116_1	525897.Dbac_1840	7.78e-239	671.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,42TI5@68525|delta/epsilon subdivisions,2WQR8@28221|Deltaproteobacteria,2MG9C@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
k59_791142_1	483219.LILAB_22900	6.49e-39	142.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,2YW3V@29|Myxococcales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k59_1065444_2	2340.JV46_27850	2.95e-57	182.0	COG0517@1|root,COG0517@2|Bacteria,1NJC6@1224|Proteobacteria,1SV2H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_1065445_1	335543.Sfum_3557	2.63e-92	276.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42SWD@68525|delta/epsilon subdivisions,2WK1W@28221|Deltaproteobacteria,2MQCQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
k59_1183266_1	392500.Swoo_2164	4.25e-24	100.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria,2Q8PT@267890|Shewanellaceae	1236|Gammaproteobacteria	L	Belongs to the DnaA family	hda	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
k59_1183266_2	396588.Tgr7_2250	5.24e-38	140.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	permease	perM	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_1065471_1	243159.AFE_1843	1.4e-98	307.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1SJQ1@1236|Gammaproteobacteria,2NDRU@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_46425_1	1459636.NTE_01195	7.73e-09	56.6	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01195|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_737416_1	9541.XP_005568870.1	5.02e-131	378.0	COG1976@1|root,KOG3185@2759|Eukaryota,38F4B@33154|Opisthokonta,3BCN0@33208|Metazoa,3CYQS@33213|Bilateria,4812A@7711|Chordata,490UY@7742|Vertebrata,3J9ZY@40674|Mammalia,35IVK@314146|Euarchontoglires,4MEWY@9443|Primates,362K1@314294|Cercopithecoidea	33208|Metazoa	J	Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity. In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G C rich or uORF in their 5'UTR. Required for ROS-dependent megakaryocyte maturation and platelets formation, controls the expression of mitochondrial respiratory chain genes involved in reactive oxygen species (ROS) synthesis. Involved in miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Modulates cell cycle progression and global translation of pre-B cells, its activation seems to be rate-limiting in tumorigenesis and tumor growth	EIF6	GO:0000054,GO:0000460,GO:0000470,GO:0002682,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005638,GO:0005652,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005856,GO:0005882,GO:0006109,GO:0006110,GO:0006139,GO:0006140,GO:0006364,GO:0006396,GO:0006403,GO:0006405,GO:0006412,GO:0006413,GO:0006417,GO:0006518,GO:0006611,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006996,GO:0008104,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009719,GO:0009725,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009987,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015031,GO:0015833,GO:0015931,GO:0016043,GO:0016070,GO:0016072,GO:0016441,GO:0016458,GO:0017148,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0030808,GO:0030811,GO:0031047,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031503,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032270,GO:0032868,GO:0032991,GO:0033036,GO:0033750,GO:0034248,GO:0034249,GO:0034250,GO:0034399,GO:0034470,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0035194,GO:0035195,GO:0035278,GO:0040029,GO:0040033,GO:0042221,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0042304,GO:0042325,GO:0042886,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043434,GO:0043467,GO:0043470,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045111,GO:0045184,GO:0045595,GO:0045637,GO:0045652,GO:0045727,GO:0045974,GO:0046483,GO:0046890,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050657,GO:0050658,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051168,GO:0051169,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051234,GO:0051236,GO:0051239,GO:0051246,GO:0051247,GO:0051248,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0070013,GO:0070727,GO:0070925,GO:0071166,GO:0071426,GO:0071428,GO:0071702,GO:0071704,GO:0071705,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:1900371,GO:1900542,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901698,GO:1901700,GO:1902626,GO:1903578,GO:1903706,GO:1990904,GO:2000026,GO:2000112,GO:2000113,GO:2000377,GO:2001169	-	ko:K03264	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009,ko03012	-	-	-	eIF-6
k59_698502_1	1123229.AUBC01000034_gene1341	1.64e-25	100.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2UBSI@28211|Alphaproteobacteria,3JY6D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
k59_698502_2	1122599.AUGR01000021_gene3213	1.36e-15	76.6	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,1XH9R@135619|Oceanospirillales	135619|Oceanospirillales	E	Aminotransferase	-	-	2.6.1.1,2.6.1.57	ko:K00813,ko:K00832	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00024,M00025,M00034,M00040	R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
k59_1016884_1	62928.azo0393	9.33e-07	50.1	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,2KYBB@206389|Rhodocyclales	206389|Rhodocyclales	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_1016884_2	743721.Psesu_1800	3.76e-93	281.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,1X30J@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
k59_814451_1	314278.NB231_10924	3.4e-14	75.1	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria,1WYPF@135613|Chromatiales	135613|Chromatiales	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
k59_814451_2	221988.MS0486	4.07e-11	63.5	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1Y7I1@135625|Pasteurellales	135625|Pasteurellales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_268300_1	717774.Marme_4163	2.57e-45	154.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,1S5Y0@1236|Gammaproteobacteria,1XK0E@135619|Oceanospirillales	135619|Oceanospirillales	Q	TRAP-type mannitol chloroaromatic compound transport system, small permease component	gtrA	-	-	-	-	-	-	-	-	-	-	-	DctQ
k59_1052198_1	572477.Alvin_1296	1.92e-46	162.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RNN1@1236|Gammaproteobacteria,1WXTE@135613|Chromatiales	135613|Chromatiales	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
k59_149264_1	398525.KB900701_gene4200	1.01e-81	249.0	COG1024@1|root,COG1024@2|Bacteria,1Q51H@1224|Proteobacteria,2TUPH@28211|Alphaproteobacteria,3JU70@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_346411_1	1120956.JHZK01000021_gene1586	5.3e-96	288.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria,1JN5X@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Cytochrome c, mono- and diheme variants	cycG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
k59_1250636_1	880072.Desac_0500	2.2e-79	250.0	COG1804@1|root,COG1804@2|Bacteria,1NWFC@1224|Proteobacteria,4300F@68525|delta/epsilon subdivisions,2X2A6@28221|Deltaproteobacteria,2MRS4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
k59_188158_1	1089551.KE386572_gene957	6.02e-72	224.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2TUHX@28211|Alphaproteobacteria,4BPS4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C1 family	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
k59_934792_1	1163409.UUA_02876	7.12e-42	157.0	COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,1XBM4@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c
k59_1091731_1	62928.azo3376	1.69e-27	111.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria,2KUKR@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
k59_1091731_2	156889.Mmc1_0981	1.47e-27	111.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria	1224|Proteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_583505_2	913325.N799_07555	6.15e-117	342.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria,1X30T@135614|Xanthomonadales	135614|Xanthomonadales	D	chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
k59_583505_3	1121939.L861_13130	4.5e-09	58.2	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1XJ8Z@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
k59_309467_1	472759.Nhal_1929	3.1e-47	155.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1WVXA@135613|Chromatiales	135613|Chromatiales	K	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
k59_309467_2	686340.Metal_3222	9.19e-15	75.1	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,1XDPS@135618|Methylococcales	135618|Methylococcales	E	TIGRFAM Serine O-acetyltransferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
k59_505048_1	1449049.JONW01000009_gene4316	1.52e-30	117.0	COG1595@1|root,COG1595@2|Bacteria,1RD9G@1224|Proteobacteria,2U92K@28211|Alphaproteobacteria,2KGJR@204458|Caulobacterales	204458|Caulobacterales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
k59_151470_1	216596.RL3800	2.63e-62	201.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,4BBWF@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
k59_897032_2	1121405.dsmv_1519	6.71e-60	196.0	COG0477@1|root,COG2814@2|Bacteria,1P2GY@1224|Proteobacteria,42MWI@68525|delta/epsilon subdivisions,2WK29@28221|Deltaproteobacteria,2MHKX@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_739841_1	335543.Sfum_1046	4.95e-127	372.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2WJYY@28221|Deltaproteobacteria,2MR3M@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
k59_816878_1	1274374.CBLK010000053_gene2327	6.36e-71	228.0	COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,26SC8@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
k59_190486_1	243233.MCA0087	2.11e-61	214.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1XDKW@135618|Methylococcales	135618|Methylococcales	NU	Neisseria PilC beta-propeller domain	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
k59_623066_1	502025.Hoch_6045	0.000429	48.5	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1Q53R@1224|Proteobacteria,430W1@68525|delta/epsilon subdivisions,2WVP7@28221|Deltaproteobacteria,2YWDG@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
k59_151509_1	1120953.AUBH01000002_gene1477	9.89e-83	257.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,1RYNM@1236|Gammaproteobacteria,46775@72275|Alteromonadaceae	1236|Gammaproteobacteria	EQ	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
k59_270771_1	243231.GSU0572	1.7e-45	159.0	COG0637@1|root,COG1514@1|root,COG0637@2|Bacteria,COG1514@2|Bacteria,1QUMB@1224|Proteobacteria,43BM1@68525|delta/epsilon subdivisions,2X6Z7@28221|Deltaproteobacteria,43URF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	HAD-superfamily hydrolase subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	Hydrolase
k59_34361_1	439235.Dalk_4073	1.87e-19	92.4	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1R7B6@1224|Proteobacteria,42QKS@68525|delta/epsilon subdivisions,2WIW2@28221|Deltaproteobacteria,2MII8@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,SpoIIE
k59_934865_1	589865.DaAHT2_1557	6.57e-25	103.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,42VSU@68525|delta/epsilon subdivisions,2WR9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
k59_934875_1	1121918.ARWE01000001_gene2276	1.67e-95	311.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,43S5H@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	RNA polymerase I subunit A N-terminus	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
k59_151548_1	1304275.C41B8_00910	2.81e-87	270.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Glutamate synthase	gltD	GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iEC042_1314.EC042_3503,iYL1228.KPN_03625	Fer4_11,Fer4_20,Pyr_redox_2
k59_1132046_1	1121374.KB891575_gene1170	1.09e-98	305.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_897130_1	596151.DesfrDRAFT_1895	8.2e-65	217.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MEP8@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k59_976276_1	1177154.Y5S_02232	0.000639	42.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1XIZA@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
k59_976276_2	1385517.N800_04220	2.02e-51	166.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1X6WU@135614|Xanthomonadales	135614|Xanthomonadales	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
k59_976276_3	1122207.MUS1_14540	9.02e-33	121.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1XH8Y@135619|Oceanospirillales	135619|Oceanospirillales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
k59_660742_1	1267005.KB911257_gene727	6.95e-37	130.0	COG5352@1|root,COG5352@2|Bacteria,1RHI6@1224|Proteobacteria,2TS7F@28211|Alphaproteobacteria,3N758@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	GcrA cell cycle regulator	gcrA	-	-	ko:K13583	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	GcrA
k59_779257_1	861299.J421_4457	2.92e-28	118.0	COG2755@1|root,COG2755@2|Bacteria,1ZUW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
k59_233449_1	493475.GARC_5346	2.56e-115	343.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,4653Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
k59_660753_1	396588.Tgr7_3027	4.76e-11	61.2	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1WYAC@135613|Chromatiales	135613|Chromatiales	NU	pilus assembly protein PilP	-	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
k59_660753_2	1304275.C41B8_00885	1.32e-15	79.3	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	(Type IV) pilus	pilQ	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_976289_1	297246.lpp3054	1.3e-34	126.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1JCPD@118969|Legionellales	118969|Legionellales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
k59_976289_2	1163408.UU9_13683	6.23e-26	105.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1X3WS@135614|Xanthomonadales	135614|Xanthomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
k59_1054673_1	1121405.dsmv_0141	1.05e-73	234.0	COG0247@1|root,COG0247@2|Bacteria,1R467@1224|Proteobacteria,42NIQ@68525|delta/epsilon subdivisions,2WIUU@28221|Deltaproteobacteria,2MQ10@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	hmcF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17
k59_623212_1	472759.Nhal_1456	1.13e-118	355.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1WWTW@135613|Chromatiales	135613|Chromatiales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_857381_1	264730.PSPPH_A0061	2.77e-51	172.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1Z7QZ@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_309644_1	396588.Tgr7_0944	1.5e-55	183.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1WXTC@135613|Chromatiales	135613|Chromatiales	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_897188_1	1232437.KL661967_gene5058	2.11e-51	173.0	COG1910@1|root,COG1910@2|Bacteria,1MVS4@1224|Proteobacteria,42NF7@68525|delta/epsilon subdivisions,2WJA9@28221|Deltaproteobacteria,2MI63@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TIGRFAM DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,PBP_like
k59_1132121_1	644282.Deba_0718	1.24e-72	233.0	COG0730@1|root,COG0730@2|Bacteria,1N1I6@1224|Proteobacteria,42N92@68525|delta/epsilon subdivisions,2WJT2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
k59_309659_1	314262.MED193_02890	6.12e-76	229.0	COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria,2U9DE@28211|Alphaproteobacteria,2P2GF@2433|Roseobacter	28211|Alphaproteobacteria	FJ	MafB19-like deaminase	MA20_41730	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
k59_505270_1	1283300.ATXB01000002_gene3071	1.65e-36	142.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1XDN9@135618|Methylococcales	135618|Methylococcales	I	Domain of unknown function (DUF1974)	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N,DUF1974
k59_1091926_1	631362.Thi970DRAFT_00007	1.17e-31	127.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,1QE1Y@1224|Proteobacteria,1RRG9@1236|Gammaproteobacteria,1X1Z7@135613|Chromatiales	135613|Chromatiales	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_233516_1	1006000.GKAS_04711	1.94e-53	178.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2826 Transposase and inactivated derivatives, IS30 family	insI	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
k59_548037_1	1121405.dsmv_2130	6.75e-87	268.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2MHWE@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
k59_1171710_1	1009858.BUMPG002_CDS00300	1.85e-21	93.2	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,37D5V@32199|Buchnera	1236|Gammaproteobacteria	F	Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184	Gp_dh_C,Gp_dh_N
k59_1171710_2	55529.EKX47121	3.75e-14	72.8	COG0057@1|root,KOG0657@2759|Eukaryota	2759|Eukaryota	G	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	GAPDH	GO:0000003,GO:0000166,GO:0000302,GO:0000768,GO:0003006,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005740,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0005911,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006949,GO:0006950,GO:0006952,GO:0006970,GO:0006979,GO:0007275,GO:0007520,GO:0007525,GO:0008150,GO:0008152,GO:0008270,GO:0008886,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009314,GO:0009408,GO:0009416,GO:0009506,GO:0009507,GO:0009536,GO:0009555,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009651,GO:0009653,GO:0009719,GO:0009725,GO:0009735,GO:0009743,GO:0009744,GO:0009791,GO:0009908,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010154,GO:0014902,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022414,GO:0022622,GO:0030016,GO:0030017,GO:0030018,GO:0030054,GO:0030154,GO:0030312,GO:0031090,GO:0031430,GO:0031672,GO:0031674,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032787,GO:0032991,GO:0033500,GO:0034059,GO:0034285,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0036293,GO:0042221,GO:0042301,GO:0042493,GO:0042542,GO:0042579,GO:0042592,GO:0042593,GO:0042692,GO:0042742,GO:0042866,GO:0043167,GO:0043168,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044437,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046677,GO:0046686,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0048037,GO:0048046,GO:0048229,GO:0048316,GO:0048364,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048646,GO:0048653,GO:0048658,GO:0048731,GO:0048827,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050801,GO:0050896,GO:0051146,GO:0051186,GO:0051188,GO:0051287,GO:0051704,GO:0051707,GO:0051775,GO:0055044,GO:0055081,GO:0055086,GO:0055114,GO:0061061,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0070403,GO:0070482,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080022,GO:0080144,GO:0090407,GO:0090567,GO:0097159,GO:0098542,GO:0098588,GO:0098805,GO:0099080,GO:0099081,GO:0099402,GO:0099512,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901700	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
k59_465687_1	215803.DB30_0755	1.26e-55	185.0	COG0596@1|root,COG0596@2|Bacteria,1R9X7@1224|Proteobacteria,42XHQ@68525|delta/epsilon subdivisions,2WSQA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_348932_1	1298880.AUEV01000018_gene291	2.62e-21	99.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
k59_151674_1	1269813.ATUL01000007_gene2070	1.84e-09	58.9	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
k59_151674_2	983548.Krodi_2378	8.54e-27	105.0	COG1719@1|root,COG1719@2|Bacteria,4NIZJ@976|Bacteroidetes,1I1NS@117743|Flavobacteriia,37EC9@326319|Dokdonia	976|Bacteroidetes	S	Haem-NO-binding	-	-	-	-	-	-	-	-	-	-	-	-	HNOB
k59_465710_1	1417296.U879_08035	6.58e-60	196.0	COG0095@1|root,COG0095@2|Bacteria,1N1T8@1224|Proteobacteria,2U1PC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
k59_1211018_1	443144.GM21_1068	1.82e-46	155.0	2EE9W@1|root,3384B@2|Bacteria,1NCE1@1224|Proteobacteria,42VUH@68525|delta/epsilon subdivisions,2WSA1@28221|Deltaproteobacteria,43V30@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit	cbcS	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1
k59_309729_1	1158292.JPOE01000002_gene2738	1.27e-30	120.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria,1KJCK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
k59_309729_2	765912.Thimo_2187	3.49e-54	182.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1WX6S@135613|Chromatiales	135613|Chromatiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
k59_190690_1	1123354.AUDR01000018_gene1176	1.45e-18	83.6	COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,2VRJ4@28216|Betaproteobacteria,1KRUU@119069|Hydrogenophilales	119069|Hydrogenophilales	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
k59_115785_1	1121405.dsmv_1954	5.03e-116	340.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,2MJ2R@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
k59_604848_1	51337.XP_004672260.1	1.03e-73	243.0	COG0724@1|root,KOG4212@2759|Eukaryota,39M82@33154|Opisthokonta,3BCYP@33208|Metazoa,3CU3Y@33213|Bilateria,481WC@7711|Chordata,48Y25@7742|Vertebrata,3J4JI@40674|Mammalia,35DAU@314146|Euarchontoglires,4PZ5Z@9989|Rodentia	33208|Metazoa	A	Heterogeneous nuclear ribonucleoprotein M	HNRNPM	GO:0000003,GO:0000228,GO:0000375,GO:0000377,GO:0000380,GO:0000398,GO:0000578,GO:0000785,GO:0000790,GO:0002237,GO:0003002,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003823,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005694,GO:0005737,GO:0006139,GO:0006396,GO:0006397,GO:0006403,GO:0006725,GO:0006807,GO:0007028,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007276,GO:0007277,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007314,GO:0007315,GO:0007316,GO:0007350,GO:0007351,GO:0007389,GO:0008150,GO:0008152,GO:0008298,GO:0008358,GO:0008380,GO:0008543,GO:0008595,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009790,GO:0009798,GO:0009880,GO:0009948,GO:0009952,GO:0009986,GO:0009987,GO:0009994,GO:0010033,GO:0010243,GO:0010467,GO:0016043,GO:0016070,GO:0016071,GO:0016363,GO:0016604,GO:0016607,GO:0019094,GO:0019904,GO:0019953,GO:0021700,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030154,GO:0031974,GO:0031981,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033993,GO:0034399,GO:0034641,GO:0035062,GO:0035282,GO:0042221,GO:0042382,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044344,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0045451,GO:0046483,GO:0048306,GO:0048468,GO:0048469,GO:0048477,GO:0048518,GO:0048599,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051179,GO:0051222,GO:0051223,GO:0051641,GO:0051704,GO:0051707,GO:0051716,GO:0060341,GO:0060810,GO:0060811,GO:0065007,GO:0070013,GO:0070201,GO:0070727,GO:0070848,GO:0070887,GO:0071013,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071363,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071774,GO:0071840,GO:0090087,GO:0090304,GO:0097159,GO:1900180,GO:1900182,GO:1901360,GO:1901363,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1903827,GO:1903829,GO:1904587,GO:1904588,GO:1904589,GO:1904591,GO:1904951,GO:1990405,GO:1990831,GO:1990904	-	ko:K12887	ko03040,map03040	-	-	-	ko00000,ko00001,ko03041	-	-	-	HnRNP_M,RRM_1
k59_839377_1	1136138.JH604625_gene3602	3.86e-50	181.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1234387_1	1265505.ATUG01000001_gene2870	4.23e-31	125.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,42NWZ@68525|delta/epsilon subdivisions,2WJU7@28221|Deltaproteobacteria,2MJ2C@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
k59_999558_1	768671.ThimaDRAFT_0015	2.87e-79	254.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1WXIB@135613|Chromatiales	135613|Chromatiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_212699_1	96561.Dole_0333	1.57e-61	202.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2MID0@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
k59_486934_1	555079.Toce_0852	1.37e-24	104.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,24AJ7@186801|Clostridia,42F8T@68295|Thermoanaerobacterales	186801|Clostridia	EQ	PFAM Hydantoinase oxoprolinase	hyuA	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
k59_486934_2	765913.ThidrDRAFT_4193	9.99e-52	175.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1WZ4R@135613|Chromatiales	135613|Chromatiales	BQ	PFAM histone deacetylase superfamily	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
k59_1074093_1	589865.DaAHT2_2277	1.82e-74	241.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria,2MHZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
k59_252064_1	1384056.N787_12340	1.9e-24	107.0	COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,1MUA6@1224|Proteobacteria,1SZXB@1236|Gammaproteobacteria,1X4T0@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the Orn Lys Arg decarboxylase class-II family	lysA	-	2.7.2.4,4.1.1.20	ko:K12526	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00451,R00480	RC00002,RC00043,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC
k59_369783_2	1408224.SAMCCGM7_c4986	3.2e-60	191.0	COG2151@1|root,COG2151@2|Bacteria,1RF3S@1224|Proteobacteria,2TRQW@28211|Alphaproteobacteria,4BAWH@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Iron-sulfur cluster assembly protein	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
k59_1038948_1	931626.Awo_c25340	8.11e-10	61.2	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,25VKD@186806|Eubacteriaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
k59_1038948_2	445971.ANASTE_01434	1.03e-24	104.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,25VJV@186806|Eubacteriaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
k59_839422_1	604354.TSIB_1619	2.79e-40	154.0	COG2414@1|root,arCOG00706@2157|Archaea,2XTUP@28890|Euryarchaeota,242U3@183968|Thermococci	2157|Archaea	C	aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_291408_1	870187.Thini_4164	8.2e-72	224.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,4609A@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
k59_447678_1	335543.Sfum_1328	1.5e-72	230.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria,43A0M@68525|delta/epsilon subdivisions,2X9UN@28221|Deltaproteobacteria,2MS7U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
k59_799622_1	857087.Metme_1733	2.09e-07	51.6	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1S0QX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	response regulator	nreC	-	-	ko:K14979	ko02020,map02020	M00663	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
k59_799622_2	1402135.SUH3_08435	6.46e-11	65.1	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VEWH@28211|Alphaproteobacteria,3ZV79@60136|Sulfitobacter	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07666,ko:K07774	ko02020,ko02024,map02020,map02024	M00453,M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_799622_3	338966.Ppro_1138	2.66e-16	78.6	COG0784@1|root,COG2202@1|root,COG3290@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3290@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,43U7B@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase A domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
k59_134013_1	879212.DespoDRAFT_02931	1.17e-36	137.0	28J8Y@1|root,2Z943@2|Bacteria,1REXC@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4338)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4338
k59_643350_1	111780.Sta7437_1142	2.49e-40	152.0	COG0642@1|root,COG0745@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1G09B@1117|Cyanobacteria,3VI8K@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,GAF,HAMP,HATPase_c,HisKA,MASE1,Response_reg,dCache_1
k59_134016_1	933262.AXAM01000005_gene2511	5.6e-72	224.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,42NX7@68525|delta/epsilon subdivisions,2WQ35@28221|Deltaproteobacteria,2MIN6@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
k59_799633_1	953739.SVEN_1000	3.13e-60	209.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,2GIYE@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase oxoprolinase	oplA	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0266c	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
k59_682885_1	338969.Rfer_0959	1.29e-33	130.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,2VPEG@28216|Betaproteobacteria,4AGU0@80864|Comamonadaceae	28216|Betaproteobacteria	C	Protein of unknown function (DUF4080)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
k59_173449_1	472759.Nhal_3085	5.77e-16	82.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1S0G9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase	Z012_05430	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
k59_16509_1	1304874.JAFY01000001_gene2605	7.89e-45	156.0	COG3382@1|root,COG3382@2|Bacteria,3TAWJ@508458|Synergistetes	508458|Synergistetes	S	B3 4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
k59_330056_1	237368.SCABRO_03606	1.24e-43	152.0	COG2426@1|root,COG2426@2|Bacteria	2|Bacteria	S	small multidrug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
k59_643368_1	568706.BN118_3675	1.43e-66	213.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,3T2IE@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
k59_96018_1	314262.MED193_05046	7.51e-93	285.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,2P19H@2433|Roseobacter	28211|Alphaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
k59_760906_1	643867.Ftrac_1901	1.33e-07	58.2	COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
k59_1074146_1	61853.ENSNLEP00000021581	6.08e-210	585.0	COG0039@1|root,KOG1495@2759|Eukaryota,38G9C@33154|Opisthokonta,3BGT7@33208|Metazoa,3CW73@33213|Bilateria,484IM@7711|Chordata,48Z2N@7742|Vertebrata,3JBRM@40674|Mammalia,359Y2@314146|Euarchontoglires,4M6BR@9443|Primates	33208|Metazoa	C	Belongs to the LDH MDH superfamily	LDHA	GO:0000166,GO:0000302,GO:0000768,GO:0001666,GO:0003674,GO:0003824,GO:0004457,GO:0004459,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005929,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006096,GO:0006113,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006949,GO:0006950,GO:0006979,GO:0007154,GO:0007275,GO:0007520,GO:0007525,GO:0007584,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009605,GO:0009628,GO:0009636,GO:0009653,GO:0009743,GO:0009746,GO:0009749,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010243,GO:0010941,GO:0010942,GO:0014070,GO:0014074,GO:0014902,GO:0015980,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019244,GO:0019249,GO:0019318,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019752,GO:0019899,GO:0019900,GO:0030154,GO:0031514,GO:0031667,GO:0031668,GO:0032501,GO:0032502,GO:0032787,GO:0034284,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035686,GO:0036094,GO:0036126,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042692,GO:0042802,GO:0042866,GO:0042981,GO:0042995,GO:0043065,GO:0043067,GO:0043068,GO:0043226,GO:0043436,GO:0043627,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044441,GO:0044444,GO:0044463,GO:0044464,GO:0046031,GO:0046034,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046939,GO:0048037,GO:0048513,GO:0048518,GO:0048522,GO:0048569,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051186,GO:0051188,GO:0051287,GO:0051591,GO:0051716,GO:0055086,GO:0055114,GO:0061061,GO:0065007,GO:0070482,GO:0071496,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097223,GO:0097729,GO:0120025,GO:0120038,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901698,GO:1901700	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
k59_1074149_1	1121439.dsat_0894	1.01e-87	273.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2WK1D@28221|Deltaproteobacteria,2M9K4@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_565335_1	177437.HRM2_03680	2.44e-27	102.0	294U0@1|root,2ZS77@2|Bacteria,1PBP0@1224|Proteobacteria,4329Q@68525|delta/epsilon subdivisions,2WY84@28221|Deltaproteobacteria,2MP66@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_565335_2	555779.Dthio_PD0351	5.12e-13	69.3	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MAFI@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	pfam abc1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
k59_447738_1	482537.XP_008574832.1	1.04e-193	537.0	COG1471@1|root,KOG0378@2759|Eukaryota,38DSV@33154|Opisthokonta,3BBBC@33208|Metazoa,3CUBC@33213|Bilateria,485XW@7711|Chordata,48WJ4@7742|Vertebrata,3J5D2@40674|Mammalia,35EJ2@314146|Euarchontoglires	33208|Metazoa	J	Belongs to the eukaryotic ribosomal protein eS4 family	RPS4X	GO:0000184,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006417,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007275,GO:0008104,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009636,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015031,GO:0015833,GO:0015935,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034248,GO:0034250,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0035770,GO:0036464,GO:0042127,GO:0042221,GO:0042493,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0045471,GO:0045727,GO:0046483,GO:0046677,GO:0046700,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051641,GO:0051649,GO:0060255,GO:0065007,GO:0070013,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:0072657,GO:0080090,GO:0090150,GO:0090304,GO:0097159,GO:0097305,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901700,GO:1990904,GO:2000112	-	ko:K02987	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	40S_S4_C,KOW,RS4NT,Ribosomal_S4e,S4
k59_957242_1	1121447.JONL01000001_gene465	1.54e-77	261.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2X7E0@28221|Deltaproteobacteria,2MHE4@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_799683_1	1415780.JPOG01000001_gene3383	3.7e-41	142.0	COG3832@1|root,COG3832@2|Bacteria,1RHJJ@1224|Proteobacteria,1S850@1236|Gammaproteobacteria,1X741@135614|Xanthomonadales	135614|Xanthomonadales	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
k59_799683_2	1394178.AWOO02000028_gene5321	4.6e-11	59.7	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4EKQF@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
k59_1074162_1	1121405.dsmv_0755	2.51e-58	192.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42M11@68525|delta/epsilon subdivisions,2WK66@28221|Deltaproteobacteria,2MI46@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_1074162_2	1121405.dsmv_0756	1.68e-139	399.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NMG@68525|delta/epsilon subdivisions,2WJ48@28221|Deltaproteobacteria,2MITM@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
k59_878733_2	1121405.dsmv_3388	5.84e-69	226.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42N1H@68525|delta/epsilon subdivisions,2WJ0R@28221|Deltaproteobacteria,2MHVX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
k59_682947_1	713586.KB900536_gene1134	1.99e-17	80.5	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,1RY1X@1236|Gammaproteobacteria,1WW3S@135613|Chromatiales	135613|Chromatiales	S	associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
k59_682947_2	631362.Thi970DRAFT_00018	9.47e-28	104.0	COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,1S56W@1236|Gammaproteobacteria,1WYDD@135613|Chromatiales	135613|Chromatiales	F	pfam nudix	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
k59_799690_1	9778.XP_004380749.1	2.27e-109	330.0	COG0526@1|root,KOG0190@2759|Eukaryota,38GTB@33154|Opisthokonta,3BC3B@33208|Metazoa,3CV6F@33213|Bilateria,488BJ@7711|Chordata,4980X@7742|Vertebrata,3J6B0@40674|Mammalia,34UVP@311790|Afrotheria	33208|Metazoa	O	Protein disulfide-isomerase A3	PDIA3	GO:0000003,GO:0001666,GO:0001669,GO:0002376,GO:0002474,GO:0002478,GO:0002479,GO:0002931,GO:0003006,GO:0003674,GO:0003756,GO:0003810,GO:0003824,GO:0004175,GO:0004197,GO:0004620,GO:0004629,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005768,GO:0005783,GO:0005788,GO:0005789,GO:0005790,GO:0005886,GO:0006457,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0007154,GO:0007275,GO:0007423,GO:0007548,GO:0007584,GO:0007610,GO:0007623,GO:0008081,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008360,GO:0009605,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009887,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0009991,GO:0010008,GO:0010033,GO:0010171,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015036,GO:0015037,GO:0016020,GO:0016021,GO:0016298,GO:0016324,GO:0016491,GO:0016667,GO:0016671,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0016788,GO:0016853,GO:0016860,GO:0016864,GO:0018149,GO:0018991,GO:0019098,GO:0019153,GO:0019538,GO:0019882,GO:0019884,GO:0022414,GO:0022603,GO:0022604,GO:0023051,GO:0023056,GO:0030139,GO:0030141,GO:0030176,GO:0030539,GO:0031090,GO:0031224,GO:0031227,GO:0031410,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031982,GO:0031984,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033273,GO:0033280,GO:0033554,GO:0033594,GO:0033595,GO:0033993,GO:0034975,GO:0034976,GO:0035112,GO:0036211,GO:0036293,GO:0036296,GO:0040002,GO:0040019,GO:0042175,GO:0042221,GO:0042287,GO:0042288,GO:0042335,GO:0042493,GO:0042578,GO:0042590,GO:0042802,GO:0042824,GO:0042825,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043170,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044321,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044432,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045138,GO:0045177,GO:0045335,GO:0045471,GO:0045995,GO:0046661,GO:0046677,GO:0048002,GO:0048511,GO:0048513,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048608,GO:0048609,GO:0048731,GO:0048806,GO:0048808,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051128,GO:0051239,GO:0051240,GO:0051716,GO:0055037,GO:0055038,GO:0055093,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0070011,GO:0070013,GO:0070482,GO:0070848,GO:0070887,GO:0071295,GO:0071305,GO:0071310,GO:0071363,GO:0071396,GO:0071407,GO:0071495,GO:0071496,GO:0071559,GO:0071560,GO:0071704,GO:0071944,GO:0080058,GO:0080184,GO:0090596,GO:0090597,GO:0090598,GO:0097223,GO:0097305,GO:0097327,GO:0097708,GO:0098588,GO:0098590,GO:0098796,GO:0098805,GO:0098827,GO:0099503,GO:0140096,GO:1901423,GO:1901564,GO:1901654,GO:1901700,GO:1901701,GO:1903332,GO:1903334,GO:1904147,GO:1904148,GO:2000026,GO:2001233,GO:2001235,GO:2001236,GO:2001238	5.3.4.1	ko:K08056	ko04141,ko04612,map04141,map04612	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04131,ko04147	-	-	-	Thioredoxin,Thioredoxin_6
k59_999716_1	1424334.W822_02720	2.36e-45	160.0	COG2141@1|root,COG2141@2|Bacteria,1MUVN@1224|Proteobacteria,2WEU1@28216|Betaproteobacteria,3T5PQ@506|Alcaligenaceae	28216|Betaproteobacteria	C	Luciferase-like monooxygenase	-	-	1.14.14.28	ko:K20938	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
k59_526514_1	1121405.dsmv_2190	7.75e-71	232.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,2MIMN@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Peptidoglycan-binding domain 1 protein	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
k59_604995_1	1232437.KL662040_gene2136	5.21e-85	265.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_96090_1	670307.HYPDE_34643	1.39e-74	241.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TR3X@28211|Alphaproteobacteria,3N64M@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	ABC transporter	uup	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD
k59_96090_2	582899.Hden_2338	2.36e-31	119.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria,3N6AD@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	GM	NmrA-like family	MA20_24380	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind
k59_487101_1	1121451.DESAM_20811	4.62e-28	117.0	COG1145@1|root,COG1145@2|Bacteria,1RIS9@1224|Proteobacteria,42TCZ@68525|delta/epsilon subdivisions,2WPJV@28221|Deltaproteobacteria,2MGEA@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
k59_173573_1	1265505.ATUG01000001_gene3010	7.9e-40	147.0	COG3156@1|root,COG3156@2|Bacteria,1PZ6I@1224|Proteobacteria,42Q46@68525|delta/epsilon subdivisions,2WM8B@28221|Deltaproteobacteria,2MI8C@213118|Desulfobacterales	28221|Deltaproteobacteria	U	General secretion pathway protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k59_212831_1	1499967.BAYZ01000048_gene2696	2.04e-91	280.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	iJN746.PP_2734	CMAS
k59_605036_1	487521.OCU_19140	1.13e-28	115.0	COG0183@1|root,COG0183@2|Bacteria,2GKFR@201174|Actinobacteria,232S0@1762|Mycobacteriaceae	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N
k59_605036_2	1415779.JOMH01000001_gene2100	5.67e-27	103.0	COG1545@1|root,COG1545@2|Bacteria,1R44D@1224|Proteobacteria,1RYXA@1236|Gammaproteobacteria,1X793@135614|Xanthomonadales	135614|Xanthomonadales	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
k59_330165_1	861299.J421_3237	5.49e-58	192.0	COG0240@1|root,COG0240@2|Bacteria,1ZTFK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
k59_839595_1	1232437.KL662020_gene705	1.92e-73	235.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_917333_1	96561.Dole_2319	6.81e-26	99.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,42TXG@68525|delta/epsilon subdivisions,2WQI4@28221|Deltaproteobacteria,2MKN6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
k59_917333_2	1121448.DGI_1190	3.34e-12	67.0	COG2204@1|root,COG2204@2|Bacteria,1RCHU@1224|Proteobacteria,42QWT@68525|delta/epsilon subdivisions,2WN23@28221|Deltaproteobacteria,2MAFK@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,STAS,STAS_2
k59_369950_1	9606.ENSP00000435412	1.85e-141	419.0	KOG0603@1|root,KOG0603@2759|Eukaryota,3AMZM@33154|Opisthokonta,3BAGS@33208|Metazoa,3CRGH@33213|Bilateria,481WS@7711|Chordata,491BW@7742|Vertebrata,3JEWU@40674|Mammalia,35ECI@314146|Euarchontoglires,4M9EA@9443|Primates,4N1N0@9604|Hominidae	33208|Metazoa	T	Protein kinase C terminal domain	RPS6KA1	GO:0001501,GO:0001558,GO:0001650,GO:0001889,GO:0001932,GO:0001933,GO:0002009,GO:0002165,GO:0002218,GO:0002221,GO:0002224,GO:0002237,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0003002,GO:0003008,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004711,GO:0004712,GO:0004857,GO:0004866,GO:0004869,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005739,GO:0005819,GO:0005829,GO:0005856,GO:0006355,GO:0006357,GO:0006417,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006974,GO:0006978,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007444,GO:0007472,GO:0007474,GO:0007476,GO:0007528,GO:0007552,GO:0007560,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007622,GO:0007623,GO:0007626,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008285,GO:0008306,GO:0008340,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0009996,GO:0010033,GO:0010259,GO:0010453,GO:0010454,GO:0010466,GO:0010468,GO:0010556,GO:0010557,GO:0010563,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010646,GO:0010648,GO:0010721,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0015630,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018193,GO:0018209,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0022008,GO:0022603,GO:0022612,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0030162,GO:0030234,GO:0030307,GO:0030330,GO:0030414,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031347,GO:0031349,GO:0031399,GO:0031400,GO:0031594,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032386,GO:0032387,GO:0032496,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0033157,GO:0033554,GO:0033993,GO:0034248,GO:0035106,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0035556,GO:0036211,GO:0036477,GO:0040008,GO:0042127,GO:0042221,GO:0042306,GO:0042308,GO:0042325,GO:0042326,GO:0042659,GO:0042682,GO:0042683,GO:0042770,GO:0042772,GO:0042981,GO:0043025,GO:0043027,GO:0043028,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043086,GO:0043154,GO:0043170,GO:0043204,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043281,GO:0043408,GO:0043409,GO:0043412,GO:0043555,GO:0043620,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044452,GO:0044456,GO:0044464,GO:0045088,GO:0045089,GO:0045202,GO:0045475,GO:0045595,GO:0045596,GO:0045597,GO:0045664,GO:0045665,GO:0045786,GO:0045861,GO:0045893,GO:0045927,GO:0045935,GO:0045936,GO:0045944,GO:0045992,GO:0045995,GO:0046532,GO:0046533,GO:0046578,GO:0046580,GO:0046822,GO:0046823,GO:0048070,GO:0048086,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048563,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0050673,GO:0050767,GO:0050768,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050808,GO:0050865,GO:0050867,GO:0050877,GO:0050890,GO:0050896,GO:0050932,GO:0050941,GO:0051049,GO:0051051,GO:0051056,GO:0051058,GO:0051093,GO:0051094,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051223,GO:0051224,GO:0051239,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051336,GO:0051346,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0051960,GO:0051961,GO:0052547,GO:0052548,GO:0060255,GO:0060284,GO:0060341,GO:0060429,GO:0060548,GO:0060562,GO:0061008,GO:0061134,GO:0061135,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070372,GO:0070373,GO:0071704,GO:0071840,GO:0072331,GO:0072574,GO:0072575,GO:0072576,GO:0080090,GO:0080134,GO:0090087,GO:0090317,GO:0097458,GO:0098772,GO:0098793,GO:0140096,GO:1900180,GO:1900181,GO:1901564,GO:1901700,GO:1902531,GO:1902532,GO:1902680,GO:1903506,GO:1903508,GO:1903827,GO:1903828,GO:1904396,GO:1904589,GO:1904590,GO:1904950,GO:2000026,GO:2000027,GO:2000112,GO:2000116,GO:2000117,GO:2000380,GO:2000381,GO:2000489,GO:2000491,GO:2001141	2.7.11.1	ko:K04373	ko04010,ko04114,ko04150,ko04714,ko04720,ko04722,ko04914,ko04931,map04010,map04114,map04150,map04714,map04720,map04722,map04914,map04931	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03019	-	-	-	Pkinase,Pkinase_C
k59_55520_1	941449.dsx2_1623	1.02e-89	277.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Q49@68525|delta/epsilon subdivisions,2X5E9@28221|Deltaproteobacteria,2M8TQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
k59_683052_1	231434.JQJH01000040_gene2900	1.41e-48	171.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,1NFM0@1224|Proteobacteria,2U1BM@28211|Alphaproteobacteria,3NCZQ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	K	ROK family	xylR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
k59_1074276_1	1500893.JQNB01000001_gene1344	3.98e-22	97.1	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1X43I@135614|Xanthomonadales	135614|Xanthomonadales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_1074276_2	1260251.SPISAL_01450	3.75e-23	92.4	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1WYPW@135613|Chromatiales	135613|Chromatiales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
k59_1234600_1	761193.Runsl_2252	9.19e-53	186.0	COG2755@1|root,COG5434@1|root,COG2755@2|Bacteria,COG5434@2|Bacteria,4NG4T@976|Bacteroidetes,47KBB@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	ko:K19172	-	-	-	-	ko00000,ko02048	-	-	-	Glyco_hydro_28,Lipase_GDSL_2,Pectate_lyase_3
k59_55531_1	1254432.SCE1572_41875	2.01e-09	63.5	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,42MNS@68525|delta/epsilon subdivisions,2WSQX@28221|Deltaproteobacteria,2YTZF@29|Myxococcales	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
k59_1192521_1	1267005.KB911259_gene3878	2.22e-99	293.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2TQXQ@28211|Alphaproteobacteria,3N6M5@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	U	MotA/TolQ/ExbB proton channel family	tolQ	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k59_411439_1	13616.ENSMODP00000012609	2.51e-97	283.0	COG2238@1|root,KOG3411@2759|Eukaryota,3A1U1@33154|Opisthokonta,3BQPZ@33208|Metazoa,3D77R@33213|Bilateria,4875D@7711|Chordata,496VE@7742|Vertebrata,3J8GH@40674|Mammalia,4K75M@9263|Metatheria	33208|Metazoa	J	Ribosomal protein S19e	RPS19	GO:0000028,GO:0000184,GO:0000462,GO:0000956,GO:0001906,GO:0002181,GO:0002262,GO:0002376,GO:0002520,GO:0002548,GO:0002682,GO:0002683,GO:0002684,GO:0002697,GO:0002698,GO:0002699,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0006997,GO:0007000,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0007275,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009605,GO:0009607,GO:0009617,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016477,GO:0017134,GO:0019222,GO:0019439,GO:0019538,GO:0019730,GO:0019838,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0023052,GO:0030097,GO:0030099,GO:0030154,GO:0030218,GO:0030490,GO:0030595,GO:0031347,GO:0031348,GO:0031349,GO:0031369,GO:0031640,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032103,GO:0032501,GO:0032502,GO:0032879,GO:0032991,GO:0033036,GO:0033365,GO:0034101,GO:0034470,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0035821,GO:0040011,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0042330,GO:0042592,GO:0042742,GO:0042802,GO:0042803,GO:0042886,GO:0043043,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044364,GO:0044391,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045047,GO:0045088,GO:0045089,GO:0045184,GO:0045595,GO:0045824,GO:0046483,GO:0046700,GO:0046907,GO:0046983,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048534,GO:0048583,GO:0048584,GO:0048585,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0048872,GO:0050727,GO:0050728,GO:0050729,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050829,GO:0050896,GO:0050900,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051259,GO:0051262,GO:0051270,GO:0051272,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0060263,GO:0060264,GO:0060265,GO:0060266,GO:0060267,GO:0060268,GO:0060284,GO:0060326,GO:0061844,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0070887,GO:0070925,GO:0070972,GO:0071674,GO:0071702,GO:0071704,GO:0071705,GO:0071826,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0080134,GO:0090150,GO:0090304,GO:0097529,GO:0098542,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02966	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19e
k59_1153045_1	869724.H6BIE2_9CAUD	1.58e-44	157.0	4QBSJ@10239|Viruses,4QUQN@35237|dsDNA viruses  no RNA stage,4QPFJ@28883|Caudovirales,4QIA7@10662|Myoviridae	10662|Myoviridae	S	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_605112_1	1424334.W822_13335	2.42e-08	61.2	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2VIDH@28216|Betaproteobacteria,3T5A8@506|Alcaligenaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18306	ko02024,map02024	M00644	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2.20,2.A.6.2.32,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_411455_1	1195246.AGRI_03469	2.98e-127	380.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,464J7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG0405 Gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
k59_134215_1	443144.GM21_3158	8.23e-16	80.5	COG3303@1|root,COG3303@2|Bacteria,1PEVM@1224|Proteobacteria	1224|Proteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_683096_1	497964.CfE428DRAFT_1237	6.2e-68	221.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
k59_16718_1	1185652.USDA257_c25000	3.95e-34	131.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,2VF65@28211|Alphaproteobacteria,4BBA2@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase for insertion sequence element	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_212938_1	1192124.LIG30_4563	6.4e-22	94.4	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria,1K3FH@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_291700_1	1121405.dsmv_1461	5.33e-96	290.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,42NTX@68525|delta/epsilon subdivisions,2WMFG@28221|Deltaproteobacteria,2MITC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	FAD dependent oxidoreductase	soxB	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
k59_252354_1	211165.AJLN01000051_gene4893	4.89e-81	251.0	COG1335@1|root,COG1335@2|Bacteria,1G10P@1117|Cyanobacteria,1JHM2@1189|Stigonemataceae	1117|Cyanobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1192595_1	1121403.AUCV01000005_gene223	1.02e-124	365.0	COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,42MPI@68525|delta/epsilon subdivisions,2WJGY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Iron-containing alcohol dehydrogenase	bdhA	-	1.1.1.1	ko:K00001,ko:K08325	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R02528,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC00739,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
k59_332515_1	1307759.JOMJ01000003_gene2286	1.63e-53	191.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,42PJV@68525|delta/epsilon subdivisions,2WKRG@28221|Deltaproteobacteria,2M98V@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
k59_1237247_2	1120966.AUBU01000001_gene992	2.43e-29	111.0	COG0517@1|root,COG0517@2|Bacteria,4NNFS@976|Bacteroidetes,47QRM@768503|Cytophagia	976|Bacteroidetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
k59_841935_1	1415778.JQMM01000001_gene483	9.05e-31	119.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,1J5T5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1	mip	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
k59_215962_1	391626.OAN307_c30700	6e-53	179.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TTAW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
k59_294093_1	935840.JAEQ01000010_gene1492	2.98e-84	264.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TS6B@28211|Alphaproteobacteria,43I0X@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Trypsin-like peptidase domain	-	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
k59_1116446_1	1713.JOFV01000001_gene1838	4.57e-07	56.2	COG1309@1|root,COG1309@2|Bacteria,2HD07@201174|Actinobacteria,4F18I@85016|Cellulomonadaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
k59_794078_1	933262.AXAM01000044_gene1408	1.99e-57	192.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,42U5W@68525|delta/epsilon subdivisions,2WQUQ@28221|Deltaproteobacteria,2MKFC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
k59_89885_1	1415779.JOMH01000001_gene3134	5.73e-101	300.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1S670@1236|Gammaproteobacteria,1X9PH@135614|Xanthomonadales	135614|Xanthomonadales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
k59_89902_1	945713.IALB_0341	1.04e-86	282.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_10736_1	553220.CAMGR0001_1998	4.08e-42	145.0	COG3676@1|root,COG3676@2|Bacteria,1QTF7@1224|Proteobacteria,42VZY@68525|delta/epsilon subdivisions,2YTCT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	manually curated	-	-	-	ko:K07488	-	-	-	-	ko00000	-	-	-	-
k59_324120_1	1454004.AW11_02264	6.63e-94	288.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,2W02U@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
k59_1068481_1	1031711.RSPO_c02847	3.87e-44	163.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1K3N3@119060|Burkholderiaceae	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
k59_1068486_2	270374.MELB17_21510	2.86e-33	129.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,4668R@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	PQQ enzyme repeat	gcd	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
k59_206602_1	709797.CSIRO_2950	2.73e-29	117.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TS1P@28211|Alphaproteobacteria,3JSWY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
k59_324144_1	398767.Glov_1954	1.34e-95	303.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,43TAY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_128389_1	1279017.AQYJ01000028_gene2268	2.86e-71	238.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWTT@1224|Proteobacteria,1RP0H@1236|Gammaproteobacteria,46CKB@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_480988_1	1121441.AUCX01000022_gene787	3.13e-54	193.0	COG0577@1|root,COG2234@1|root,COG0577@2|Bacteria,COG2234@2|Bacteria,1MVYE@1224|Proteobacteria,42PKN@68525|delta/epsilon subdivisions,2WIWP@28221|Deltaproteobacteria,2M8ZJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,PA,Peptidase_M28
k59_403246_1	396588.Tgr7_3066	1.17e-17	77.8	COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,1SCNZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	DnaK suppressor protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
k59_403246_2	225937.HP15_3456	2.84e-27	102.0	COG2841@1|root,COG2841@2|Bacteria,1N760@1224|Proteobacteria,1SCCY@1236|Gammaproteobacteria,4698E@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
k59_755128_1	469383.Cwoe_0001	9.58e-25	109.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CPFC@84995|Rubrobacteria	84995|Rubrobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_1068519_1	335543.Sfum_3743	1.7e-47	165.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MQRN@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
k59_676901_1	1123373.ATXI01000003_gene1333	3.23e-15	73.2	2EAAE@1|root,334ER@2|Bacteria,2GHMY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_676901_2	273068.TTE0874	2.61e-40	151.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,42FDS@68295|Thermoanaerobacterales	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_1226564_1	9601.ENSPPYP00000015495	1.63e-96	297.0	KOG2842@1|root,KOG2842@2759|Eukaryota,38EW2@33154|Opisthokonta,3B9K5@33208|Metazoa,3CYQ8@33213|Bilateria,4889S@7711|Chordata,496BT@7742|Vertebrata,3JBM7@40674|Mammalia,35I8E@314146|Euarchontoglires,4MG9R@9443|Primates,4MVY7@9604|Hominidae	33208|Metazoa	Z	Interferon-related protein conserved region	IFRD2	-	-	-	-	-	-	-	-	-	-	-	IFRD,IFRD_C
k59_637822_1	1487923.DP73_09960	9.47e-07	55.5	COG4974@1|root,COG4974@2|Bacteria,1V1FM@1239|Firmicutes,24H96@186801|Clostridia,2629E@186807|Peptococcaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
k59_50095_1	335543.Sfum_2600	1.94e-50	172.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_403312_1	195250.CM001776_gene600	3.2e-47	167.0	COG0534@1|root,COG0534@2|Bacteria,1G2M4@1117|Cyanobacteria	1117|Cyanobacteria	V	efflux protein, MATE family	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
k59_50106_1	61853.ENSNLEP00000006910	1.59e-78	244.0	COG2163@1|root,KOG3421@2759|Eukaryota,3A5KJ@33154|Opisthokonta,3BPM4@33208|Metazoa,3D4IM@33213|Bilateria,487C9@7711|Chordata,49756@7742|Vertebrata,3J9GP@40674|Mammalia,35AAR@314146|Euarchontoglires,4MEHE@9443|Primates	33208|Metazoa	J	ribosomal protein L14	RPL14	GO:0000184,GO:0000956,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005791,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0010941,GO:0012505,GO:0015031,GO:0015833,GO:0015934,GO:0016020,GO:0016070,GO:0016071,GO:0016072,GO:0019222,GO:0019439,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030867,GO:0031090,GO:0031984,GO:0032991,GO:0033036,GO:0033365,GO:0034470,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0042175,GO:0042254,GO:0042273,GO:0042886,GO:0042981,GO:0043043,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043523,GO:0043524,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060255,GO:0060548,GO:0065007,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:0098552,GO:0098554,GO:0098556,GO:0098562,GO:0098588,GO:0098827,GO:1901214,GO:1901215,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02875	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14e
k59_951213_1	522306.CAP2UW1_3619	1.47e-95	291.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2VJJ7@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
k59_598882_1	933262.AXAM01000138_gene121	5.19e-88	267.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIA4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
k59_206691_2	1045855.DSC_14395	3.23e-13	64.7	2EGSV@1|root,33AIZ@2|Bacteria,1NGPG@1224|Proteobacteria,1SGM3@1236|Gammaproteobacteria,1X8YC@135614|Xanthomonadales	135614|Xanthomonadales	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
k59_206691_3	1121948.AUAC01000003_gene2869	4.88e-10	62.8	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,43X3G@69657|Hyphomonadaceae	28211|Alphaproteobacteria	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
k59_951217_1	384765.SIAM614_25507	1.54e-30	121.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2TVZH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Mg2 and Co2 transporter CorB	corB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
k59_951217_2	335543.Sfum_3770	3.46e-53	171.0	COG1259@1|root,COG1259@2|Bacteria	2|Bacteria	K	PFAM Uncharacterised ACR, COG1259	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03617,ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
k59_403355_1	161934.XP_010693843.1	1.71e-72	243.0	COG0265@1|root,KOG1421@2759|Eukaryota,37M01@33090|Viridiplantae,3G8IE@35493|Streptophyta	35493|Streptophyta	O	protease do-like	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_1,PDZ_2,Trypsin_2
k59_481088_1	1122137.AQXF01000002_gene191	1.03e-86	266.0	COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,2TTDX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	MA20_44650	-	-	-	-	-	-	-	-	-	-	-	DUF58
k59_481088_2	1147128.BAST_1095	9.17e-06	47.4	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CZ2I@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
k59_1147067_1	582402.Hbal_1161	1.49e-86	266.0	COG0686@1|root,COG0686@2|Bacteria,1MW4P@1224|Proteobacteria	1224|Proteobacteria	E	PFAM alanine dehydrogenase PNT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
k59_90048_1	373903.Hore_10710	7.85e-58	205.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,3WAD9@53433|Halanaerobiales	186801|Clostridia	S	PFAM Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
k59_1226646_1	876044.IMCC3088_2536	1.05e-64	207.0	COG3949@1|root,COG3949@2|Bacteria,1QAYU@1224|Proteobacteria	1224|Proteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1108125_1	768670.Calni_1741	2.37e-49	163.0	COG0279@1|root,COG0279@2|Bacteria,2GFD6@200930|Deferribacteres	200930|Deferribacteres	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
k59_716821_1	1002809.SSIL_1377	1.12e-21	93.2	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,4HBQC@91061|Bacilli,26D5V@186818|Planococcaceae	91061|Bacilli	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
k59_677008_1	1122129.AUEF01000001_gene948	7.38e-13	69.7	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,4GY6P@90964|Staphylococcaceae	91061|Bacilli	D	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
k59_1226677_1	1123253.AUBD01000005_gene130	5.07e-08	59.3	COG0265@1|root,COG0265@2|Bacteria,1PCJA@1224|Proteobacteria,1SXM8@1236|Gammaproteobacteria,1X6DM@135614|Xanthomonadales	135614|Xanthomonadales	O	PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
k59_872747_1	622637.KE124774_gene2949	2.02e-38	137.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,36XK5@31993|Methylocystaceae	28211|Alphaproteobacteria	S	ATPases associated with a variety of cellular activities	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
k59_90089_1	420662.Mpe_A1031	6.73e-17	79.7	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria,1KJ25@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Type II secretory pathway, component ExeA	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
k59_90089_2	1128427.KB904821_gene4534	1.72e-09	61.2	COG1450@1|root,COG1450@2|Bacteria,1G1WE@1117|Cyanobacteria,1H7MF@1150|Oscillatoriales	1117|Cyanobacteria	NU	Bacterial type II and III secretion system protein	gspD	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
k59_794291_1	1040989.AWZU01000004_gene7043	9.55e-54	182.0	COG3547@1|root,COG3547@2|Bacteria,1Q4TE@1224|Proteobacteria,2TT7C@28211|Alphaproteobacteria,3JUK3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_92635_1	1121405.dsmv_0142	2.55e-64	204.0	COG2181@1|root,COG2181@2|Bacteria,1RADK@1224|Proteobacteria,42RA7@68525|delta/epsilon subdivisions,2WMPI@28221|Deltaproteobacteria,2MJKM@213118|Desulfobacterales	28221|Deltaproteobacteria	C	nitrate reductase activity	hmcE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
k59_170117_1	1121920.AUAU01000010_gene48	4.44e-60	198.0	COG0132@1|root,COG0132@2|Bacteria	2|Bacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.21,6.3.2.3,6.3.3.3	ko:K00857,ko:K01920,ko:K01935	ko00240,ko00270,ko00480,ko00780,ko00983,ko01100,map00240,map00270,map00480,map00780,map00983,map01100	M00118,M00123,M00573,M00577	R00497,R01567,R02099,R03182,R08233,R10994	RC00002,RC00017,RC00096,RC00141,RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,TK
k59_483696_1	1128111.HMPREF0870_01713	1e-25	105.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,4H32B@909932|Negativicutes	909932|Negativicutes	H	Belongs to the precorrin methyltransferase family	cobA	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
k59_483696_2	118161.KB235922_gene3246	1.65e-17	82.8	COG0181@1|root,COG0181@2|Bacteria,1G213@1117|Cyanobacteria,3VIN0@52604|Pleurocapsales	1117|Cyanobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
k59_248730_1	439235.Dalk_4509	9.61e-31	120.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,434AT@68525|delta/epsilon subdivisions,2X9GM@28221|Deltaproteobacteria,2MNQ4@213118|Desulfobacterales	28221|Deltaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_953802_1	1117318.PRUB_19719	2.9e-09	63.5	COG0491@1|root,COG0491@2|Bacteria,1QKM9@1224|Proteobacteria,1SDTM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1189092_1	1304885.AUEY01000026_gene3546	1.87e-30	108.0	COG1148@1|root,COG1148@2|Bacteria,1NA53@1224|Proteobacteria,42V92@68525|delta/epsilon subdivisions,2WS6E@28221|Deltaproteobacteria,2MM0X@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8,Pyr_redox_2
k59_1189092_2	335543.Sfum_1977	6.24e-33	127.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
k59_406765_1	997346.HMPREF9374_1804	5.31e-18	84.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,4HD12@91061|Bacilli	91061|Bacilli	S	acetoin utilization protein	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
k59_796643_1	402626.Rpic_2858	2.9e-76	239.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,1K2VU@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
k59_914100_1	991905.SL003B_1307	7.4e-116	365.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,4BTG1@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Vitamin B12 dependent methionine synthase, activation domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
k59_248752_2	767817.Desgi_3841	1.02e-29	117.0	COG0446@1|root,COG1148@1|root,COG0446@2|Bacteria,COG1148@2|Bacteria,1V5YJ@1239|Firmicutes,248CC@186801|Clostridia	1239|Firmicutes	C	binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
k59_836206_1	1499967.BAYZ01000093_gene4029	7.9e-68	215.0	COG1216@1|root,COG1216@2|Bacteria,2NP6P@2323|unclassified Bacteria	2|Bacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
k59_1230147_1	398580.Dshi_3180	9.85e-114	343.0	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2U2TJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	nitrite reductase	nirS	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
k59_1110672_1	318167.Sfri_2281	3.35e-25	100.0	COG1863@1|root,COG1863@2|Bacteria,1MZYJ@1224|Proteobacteria,1S7Z3@1236|Gammaproteobacteria,2QBMS@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM cation antiporter	mnhE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
k59_875365_1	1049564.TevJSym_aq00680	1.65e-79	242.0	COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1JBVX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfE2	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
k59_640350_1	502025.Hoch_0403	6.31e-21	94.7	COG2268@1|root,COG2268@2|Bacteria,1QIR4@1224|Proteobacteria,42Q0N@68525|delta/epsilon subdivisions,2WJDJ@28221|Deltaproteobacteria,2YX5U@29|Myxococcales	28221|Deltaproteobacteria	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
k59_640350_2	502025.Hoch_4575	1.29e-05	46.6	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2YUPP@29|Myxococcales	28221|Deltaproteobacteria	H	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1149665_1	9606.ENSP00000378812	2.6e-44	147.0	KOG4090@1|root,KOG4090@2759|Eukaryota,3A5YP@33154|Opisthokonta,3BSMU@33208|Metazoa,3D9I7@33213|Bilateria,48DMJ@7711|Chordata,49B3J@7742|Vertebrata,3JD0J@40674|Mammalia,35PX0@314146|Euarchontoglires,4MJAJ@9443|Primates,4MVN7@9604|Hominidae	33208|Metazoa	K	regulation of cellular response to hypoxia	CHCHD2	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0006355,GO:0006357,GO:0006996,GO:0007005,GO:0008134,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043565,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045893,GO:0045935,GO:0045944,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070013,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0097159,GO:1900037,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	CHCH
k59_757765_1	1128421.JAGA01000001_gene2283	2.53e-16	84.3	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	GerE
k59_444501_1	95619.PM1_0220750	4.3e-36	128.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
k59_444501_2	1156919.QWC_03593	5.62e-17	80.9	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,2VIWW@28216|Betaproteobacteria,3T5MT@506|Alcaligenaceae	28216|Betaproteobacteria	K	Regulatory protein Ada 2	ada	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
k59_1149675_1	713586.KB900536_gene1958	2e-33	124.0	COG1595@1|root,COG1595@2|Bacteria,1R9ZN@1224|Proteobacteria,1S27W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigV	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_679605_2	335543.Sfum_1572	5.04e-49	160.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,42QX0@68525|delta/epsilon subdivisions,2WNBN@28221|Deltaproteobacteria,2MRKN@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS5 family	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_248800_1	1411123.JQNH01000001_gene2123	7.9e-150	450.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Formate dehydrogenase, alpha subunit	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_248800_2	460265.Mnod_5227	5.9e-07	50.4	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria,1JSA9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	nuoEF	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
k59_914166_1	359.CN09_03510	6.06e-77	240.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,2UEQQ@28211|Alphaproteobacteria,4BC7V@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,rve,rve_3
k59_131027_1	1123355.JHYO01000017_gene3628	1.42e-36	133.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,2TUHN@28211|Alphaproteobacteria,36ZY7@31993|Methylocystaceae	28211|Alphaproteobacteria	H	ABC-type tungstate transport system, periplasmic component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
k59_601611_1	1121087.AUCK01000006_gene551	3.5e-25	97.4	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,1ZFMY@1386|Bacillus	91061|Bacilli	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
k59_601611_2	1121405.dsmv_3572	3.46e-22	87.4	COG1841@1|root,COG1841@2|Bacteria,1PU2T@1224|Proteobacteria,42WNP@68525|delta/epsilon subdivisions,2WRZZ@28221|Deltaproteobacteria,2MM1B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
k59_914183_1	1235798.C817_00485	4.69e-48	167.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,27V10@189330|Dorea	186801|Clostridia	H	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_209435_1	439235.Dalk_4840	1.04e-42	159.0	COG0247@1|root,COG1150@1|root,COG2181@1|root,COG0247@2|Bacteria,COG1150@2|Bacteria,COG2181@2|Bacteria,1R44N@1224|Proteobacteria,42NTE@68525|delta/epsilon subdivisions,2WJN8@28221|Deltaproteobacteria,2MJEV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,Nitrate_red_gam
k59_562094_1	96561.Dole_2483	1.08e-46	170.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2MIJD@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
k59_970862_2	1122197.ATWI01000012_gene709	3.21e-06	48.5	COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis signal transduction protein	chpC	-	-	ko:K06598	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
k59_891771_1	933262.AXAM01000046_gene140	4.22e-58	194.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,2MI0S@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM peptidase	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
k59_734706_1	1121405.dsmv_1354	6.5e-33	130.0	COG0308@1|root,COG0308@2|Bacteria,1PEPK@1224|Proteobacteria,42NJ8@68525|delta/epsilon subdivisions,2WM57@28221|Deltaproteobacteria,2MMZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0348	Peptidase_M1
k59_774070_2	1049564.TevJSym_ad01070	4.28e-66	216.0	COG0025@1|root,COG0025@2|Bacteria,1QTW8@1224|Proteobacteria,1T3I4@1236|Gammaproteobacteria,1J8DB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
k59_304421_2	1437824.BN940_15161	5.81e-20	90.1	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2VHCS@28216|Betaproteobacteria,3T1IE@506|Alcaligenaceae	28216|Betaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_1014155_1	519989.ECTPHS_12398	2.9e-69	232.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales	135613|Chromatiales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
k59_265551_1	883078.HMPREF9695_01462	5.77e-67	222.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2TW3X@28211|Alphaproteobacteria,3K6S8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_8,PAS_9,Sigma54_activat
k59_618016_1	316273.XCV3144	2.12e-122	367.0	COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,1RMJY@1236|Gammaproteobacteria,1X3VU@135614|Xanthomonadales	135614|Xanthomonadales	E	Tryptophan halogenase	-	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
k59_384000_1	1144275.COCOR_00242	2.65e-12	72.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,1R49D@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
k59_811727_1	331869.BAL199_28440	1.36e-167	478.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,4BP7N@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
k59_811727_2	631362.Thi970DRAFT_04763	1.11e-156	446.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RMF2@1236|Gammaproteobacteria,1X0ZR@135613|Chromatiales	135613|Chromatiales	O	HflC and HflK could regulate a protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
k59_185548_1	1232410.KI421419_gene2503	4.92e-88	267.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria,42NYF@68525|delta/epsilon subdivisions,2WIT2@28221|Deltaproteobacteria,43SFJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
k59_1126912_1	948106.AWZT01000022_gene3689	1.23e-30	119.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIX2@28216|Betaproteobacteria,1K2AF@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_228157_1	399741.Spro_4714	5.93e-74	239.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,4005U@613|Serratia	1236|Gammaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	iZ_1308.Z4900	Pyr_redox_2,Pyr_redox_dim
k59_1014214_1	439375.Oant_3596	3.51e-40	150.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2TT6P@28211|Alphaproteobacteria,1J1SX@118882|Brucellaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k59_500147_1	670307.HYPDE_41763	1.73e-66	223.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,3N6MB@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	Peptidase M23	MA20_20375	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_428185_1	270374.MELB17_13966	2.6e-88	271.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,464GC@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	4.4.1.11	ko:K01761,ko:K10764	ko00270,ko00450,ko00920,ko01100,map00270,map00450,map00920,map01100	-	R00654,R01288,R04770	RC00020,RC00196,RC00348,RC01209,RC01210,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1166285_1	411464.DESPIG_02828	1.79e-12	63.9	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2WNNA@28221|Deltaproteobacteria,2MC4D@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
k59_1166285_2	439235.Dalk_2889	1.41e-15	70.9	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,42VDU@68525|delta/epsilon subdivisions,2WQZ5@28221|Deltaproteobacteria,2MKK3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
k59_304497_1	1132836.RCCGE510_20494	1.68e-82	261.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,4BA8Y@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
k59_811776_1	323850.Shew_0984	5.21e-52	179.0	COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,1SWQX@1236|Gammaproteobacteria,2QCYP@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_929897_1	572477.Alvin_1555	1.48e-22	99.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1RPAE@1236|Gammaproteobacteria,1WYC8@135613|Chromatiales	135613|Chromatiales	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_929912_1	398578.Daci_5942	9.28e-11	63.2	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VH24@28216|Betaproteobacteria,4ACYN@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
k59_698546_1	697282.Mettu_1827	2.45e-22	93.6	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1S6FG@1236|Gammaproteobacteria,1XF04@135618|Methylococcales	135618|Methylococcales	S	pfam ammecr1	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1
k59_698546_2	1027273.GZ77_11095	9.42e-36	129.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1XJIC@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
k59_188171_1	1042377.AFPJ01000016_gene119	4.94e-67	228.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464AK@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
k59_149313_1	981223.AIED01000019_gene603	2.92e-49	176.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,3NKNI@468|Moraxellaceae	1236|Gammaproteobacteria	Q	MlaD protein	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
k59_932569_1	880072.Desac_1210	2.19e-77	246.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2MQ9R@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
k59_1016984_1	270374.MELB17_22515	5.95e-108	322.0	COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,1T7KM@1236|Gammaproteobacteria,46C37@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1089504_2	555779.Dthio_PD0504	6.5e-81	260.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,431TI@68525|delta/epsilon subdivisions,2WWAP@28221|Deltaproteobacteria,2MB98@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc,DUF4338
k59_1016996_1	374847.Kcr_0087	7.01e-72	230.0	COG0334@1|root,arCOG01352@2157|Archaea	2157|Archaea	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA1	GO:0000166,GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005488,GO:0006082,GO:0006103,GO:0006520,GO:0006536,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0022607,GO:0034214,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051259,GO:0051287,GO:0055114,GO:0065003,GO:0070401,GO:0070402,GO:0070403,GO:0070404,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_307225_1	1232410.KI421421_gene3869	2.03e-99	301.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
k59_737536_1	1042377.AFPJ01000020_gene2063	8.69e-101	311.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
k59_1017013_1	1049564.TevJSym_bb00050	7.43e-82	260.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
k59_1129727_1	1101192.KB910516_gene2607	3.7e-29	111.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2U7FV@28211|Alphaproteobacteria,1JUVF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
k59_814556_1	880073.Calab_0529	3.1e-69	236.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,2NRCG@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M28	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	iAF987.Gmet_0348	Cofac_haem_bdg,PA,PDZ_2,Peptidase_M1,Peptidase_M28,Trypsin_2
k59_698610_1	247634.GPB2148_145	2.12e-34	132.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,1RRDF@1236|Gammaproteobacteria,1JBTR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	nylA	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
k59_814564_1	796620.VIBC2010_12639	4.79e-56	185.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,1XSBH@135623|Vibrionales	135623|Vibrionales	S	Displays ATPase and GTPase activities	yhbJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
k59_698629_1	998674.ATTE01000001_gene2676	5.79e-93	291.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,4601N@72273|Thiotrichales	72273|Thiotrichales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
k59_307262_1	998674.ATTE01000001_gene3489	8.88e-110	338.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,45ZT1@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1208590_1	1207055.C100_15280	1.11e-107	326.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2U401@28211|Alphaproteobacteria,2K3DC@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase domain (DUF772)	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
k59_932688_1	1265313.HRUBRA_02711	1.08e-18	90.5	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014,ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.2	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
k59_502974_1	744980.TRICHSKD4_1117	5.13e-21	84.7	28X21@1|root,2ZJ0N@2|Bacteria,1P9K6@1224|Proteobacteria,2UVXP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_658454_1	1123248.KB893363_gene4933	1.89e-49	170.0	COG4974@1|root,COG4974@2|Bacteria,4NGE1@976|Bacteroidetes,1IRMS@117747|Sphingobacteriia	976|Bacteroidetes	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
k59_1129797_1	344747.PM8797T_10444	8.75e-45	163.0	COG0668@1|root,COG0668@2|Bacteria,2J2C2@203682|Planctomycetes	203682|Planctomycetes	M	Mechanosensitive ion channel	-	-	-	ko:K03442,ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.2,1.A.23.3	-	-	MS_channel
k59_737647_1	1225184.ALXE01000066_gene2880	7.92e-07	54.7	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,3VYVW@53335|Pantoea	1236|Gammaproteobacteria	I	Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE)	clsC	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_737647_2	1198452.Jab_2c09850	1.72e-34	120.0	COG0346@1|root,COG0346@2|Bacteria,1RH8Z@1224|Proteobacteria	1224|Proteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
k59_346591_1	1121405.dsmv_0657	9.77e-85	267.0	COG3894@1|root,COG3894@2|Bacteria,1MX9D@1224|Proteobacteria,42PW1@68525|delta/epsilon subdivisions,2WJZD@28221|Deltaproteobacteria,2MHZX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445
k59_814665_1	247633.GP2143_05985	9.33e-84	276.0	28HKI@1|root,2Z7VC@2|Bacteria,1MW0I@1224|Proteobacteria,1RQ5H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1129817_1	552811.Dehly_0707	2.05e-57	201.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,2G6SR@200795|Chloroflexi,34CV6@301297|Dehalococcoidia	200795|Chloroflexi	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00266,ko:K03388	ko00250,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00250,map00680,map00910,map01100,map01110,map01120,map01130,map01200,map01230	M00356,M00357,M00563,M00567	R00093,R00114,R00248,R04540,R11928,R11931,R11943,R11944	RC00006,RC00010,RC00011,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
k59_932765_1	9940.ENSOARP00000001182	4.66e-138	392.0	COG2007@1|root,KOG3283@2759|Eukaryota,38C25@33154|Opisthokonta,3BCIX@33208|Metazoa,3CRQH@33213|Bilateria,47ZJ0@7711|Chordata,48V0P@7742|Vertebrata,3JEWV@40674|Mammalia,4IXUN@91561|Cetartiodactyla	33208|Metazoa	J	ribosomal protein S8	RPS8	GO:0000184,GO:0000462,GO:0000956,GO:0002164,GO:0002181,GO:0002376,GO:0002520,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007275,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009790,GO:0009791,GO:0009792,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0012505,GO:0015031,GO:0015833,GO:0015935,GO:0016070,GO:0016071,GO:0016072,GO:0019222,GO:0019439,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030097,GO:0030490,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034470,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0035166,GO:0035167,GO:0042254,GO:0042274,GO:0042886,GO:0043009,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048513,GO:0048519,GO:0048534,GO:0048542,GO:0048569,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051726,GO:0060255,GO:0065007,GO:0070013,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02995	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8e
k59_463418_1	1279038.KB907337_gene493	2.47e-91	280.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2TR20@28211|Alphaproteobacteria,2JPF7@204441|Rhodospirillales	204441|Rhodospirillales	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
k59_1052379_1	1026882.MAMP_00019	2.47e-64	202.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,460DQ@72273|Thiotrichales	72273|Thiotrichales	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
k59_113508_1	1205680.CAKO01000038_gene1599	7.6e-94	285.0	COG2141@1|root,COG2141@2|Bacteria,1MWMV@1224|Proteobacteria,2TTIQ@28211|Alphaproteobacteria,2JSHD@204441|Rhodospirillales	204441|Rhodospirillales	C	Luciferase-like monooxygenase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
k59_814725_1	2340.JV46_27250	5.72e-34	134.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1J4N3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008289,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042277,GO:0042546,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071723,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iECIAI39_1322.ECIAI39_0153,iSBO_1134.SBO_0138,iSbBS512_1146.SbBS512_E0140,iYL1228.KPN_00164	PBP1_TM,Transgly,Transpeptidase,UB2H
k59_1089662_1	765912.Thimo_2923	4.23e-106	311.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1WXZW@135613|Chromatiales	135613|Chromatiales	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
k59_1250824_2	335543.Sfum_0068	5.83e-60	203.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MR6X@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_231151_1	652103.Rpdx1_4081	1.53e-50	177.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria,3JZ7D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
k59_658565_1	983545.Glaag_3424	3.66e-56	187.0	COG3055@1|root,COG3055@2|Bacteria,1MYEH@1224|Proteobacteria,1RZGG@1236|Gammaproteobacteria,466M3@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	PFAM Kelch	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_2,Kelch_3,Kelch_6
k59_1089689_1	876044.IMCC3088_857	3.35e-58	191.0	COG2304@1|root,COG2304@2|Bacteria,1QBPM@1224|Proteobacteria,1RQIU@1236|Gammaproteobacteria,1J4PZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Secreted protein, containing von Willebrand factor (VWF) type	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_777034_1	717231.Flexsi_0713	1.59e-30	119.0	COG0174@1|root,COG0174@2|Bacteria,2GG7C@200930|Deferribacteres	200930|Deferribacteres	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_1129867_1	1121479.AUBS01000009_gene1542	2.03e-26	108.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2TSHK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
k59_1129867_2	338963.Pcar_2241	7.6e-34	123.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TXE@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Tryptophan synthase alpha chain	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_268590_1	1260251.SPISAL_01820	1.67e-22	101.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,1RNP1@1236|Gammaproteobacteria,1WWFF@135613|Chromatiales	135613|Chromatiales	V	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
k59_581384_1	1123253.AUBD01000015_gene904	4.17e-126	367.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1X3ZT@135614|Xanthomonadales	135614|Xanthomonadales	C	Heme copper-type cytochrome quinol oxidase subunit 3	cox3	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
k59_463487_1	706587.Desti_2572	6.31e-105	335.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,42MVK@68525|delta/epsilon subdivisions,2WKEN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
k59_503091_1	207559.Dde_0326	7.33e-22	99.8	COG1055@1|root,COG1055@2|Bacteria,1QUC0@1224|Proteobacteria,42NUZ@68525|delta/epsilon subdivisions,2WJNH@28221|Deltaproteobacteria,2M9FX@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Sodium sulphate symporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
k59_737758_1	880073.Calab_0319	1.01e-11	70.5	COG3604@1|root,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	nifA	-	-	ko:K02584,ko:K11914	ko02020,map02020	-	-	-	ko00000,ko00001,ko02044,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
k59_503104_1	1449080.JQMV01000003_gene1239	7.84e-63	211.0	COG3842@1|root,COG3842@2|Bacteria,1WIB1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC transporter	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
k59_831446_2	555778.Hneap_0004	3.76e-78	259.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1WVZ4@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
k59_1066629_1	177437.HRM2_48470	9.75e-15	71.6	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WNF6@28221|Deltaproteobacteria,2MJZ4@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
k59_478963_1	1121423.JONT01000009_gene1510	5.62e-35	134.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,260S3@186807|Peptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_478963_2	2754.EH55_05640	4.62e-05	44.7	COG0129@1|root,COG0129@2|Bacteria,3TC4V@508458|Synergistetes	508458|Synergistetes	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
k59_635852_1	335543.Sfum_1613	6.85e-63	201.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2MQHR@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PP-loop family	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
k59_674880_1	1047013.AQSP01000106_gene1765	4.4e-85	263.0	COG1509@1|root,COG1509@2|Bacteria,2NNY6@2323|unclassified Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA	-	5.4.3.2,5.4.3.9	ko:K01843,ko:K19810,ko:K19814	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
k59_831476_1	754436.JCM19237_3222	6.01e-76	240.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1XT9Q@135623|Vibrionales	135623|Vibrionales	F	Belongs to the GARS family	purD	GO:0003674,GO:0003824,GO:0004637,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
k59_831476_2	1397528.Q671_11985	5.97e-45	158.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1XH25@135619|Oceanospirillales	135619|Oceanospirillales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_518513_1	633131.TR2A62_2248	8.87e-69	215.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
k59_204517_2	335543.Sfum_1403	2.09e-80	249.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MEG@68525|delta/epsilon subdivisions,2WMGY@28221|Deltaproteobacteria,2MRER@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
k59_792351_1	340177.Cag_0243	3.32e-43	154.0	COG0834@1|root,COG0834@2|Bacteria,1FEHW@1090|Chlorobi	1090|Chlorobi	ET	PFAM extracellular solute-binding protein family 3	-	-	-	-	-	-	-	-	-	-	-	-	Lig_chan,SBP_bac_3
k59_361904_1	1121015.N789_03595	9.5e-53	181.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1X4NW@135614|Xanthomonadales	135614|Xanthomonadales	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
k59_874134_2	713587.THITH_02750	2.29e-37	138.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1WW9V@135613|Chromatiales	135613|Chromatiales	J	TIGRFAM ribonuclease, Rne Rng family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
k59_247667_2	1532557.JL37_25260	1.63e-48	158.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2WF7W@28216|Betaproteobacteria,3T4A4@506|Alcaligenaceae	28216|Betaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
k59_795594_1	933262.AXAM01000079_gene2202	3.89e-108	345.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2MI5C@213118|Desulfobacterales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
k59_1228623_1	1056816.JAFQ01000004_gene3852	1.09e-35	130.0	COG0500@1|root,COG2226@2|Bacteria,2HJ63@201174|Actinobacteria,4G5FG@85025|Nocardiaceae	201174|Actinobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
k59_286695_2	1304885.AUEY01000002_gene380	8.02e-20	85.9	COG3168@1|root,COG3168@2|Bacteria,1N39F@1224|Proteobacteria,42U30@68525|delta/epsilon subdivisions,2WRT8@28221|Deltaproteobacteria,2MPRF@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilP	-	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
k59_913047_1	95619.PM1_0201410	1.3e-92	305.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_1033234_1	1002672.SAR11G3_01377	1.88e-75	239.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2TQP6@28211|Alphaproteobacteria,4BP8J@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM FAD binding domain of DNA photolyase	phrB	GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
k59_1033234_2	1002340.AFCF01000042_gene2057	1.44e-37	131.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,34FPH@302485|Phaeobacter	28211|Alphaproteobacteria	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
k59_993766_1	935567.JAES01000003_gene234	5.73e-96	290.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1X45S@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_1033261_1	298386.PBPRB0288	1.38e-17	84.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1XVPF@135623|Vibrionales	135623|Vibrionales	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_12350_2	992406.RIA_0281	1.05e-32	115.0	COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1I3W5@117743|Flavobacteriia	976|Bacteroidetes	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
k59_1228724_1	572477.Alvin_1458	1.89e-120	357.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,1WXQP@135613|Chromatiales	135613|Chromatiales	U	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
k59_129984_1	9606.ENSP00000327801	0.0	995.0	COG0526@1|root,KOG0190@2759|Eukaryota,38GTB@33154|Opisthokonta,3BBAA@33208|Metazoa,3CY8R@33213|Bilateria,483RB@7711|Chordata,493B3@7742|Vertebrata,3J88Q@40674|Mammalia,35AWX@314146|Euarchontoglires,4ME7U@9443|Primates,4N367@9604|Hominidae	33208|Metazoa	O	protein disulfide isomerase activity	P4HB	GO:0001666,GO:0003674,GO:0003756,GO:0003810,GO:0003824,GO:0004656,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005793,GO:0005886,GO:0006082,GO:0006457,GO:0006464,GO:0006520,GO:0006575,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0009628,GO:0009897,GO:0009966,GO:0009986,GO:0009987,GO:0010033,GO:0010646,GO:0010941,GO:0012505,GO:0015036,GO:0015037,GO:0016020,GO:0016043,GO:0016222,GO:0016491,GO:0016667,GO:0016705,GO:0016706,GO:0016740,GO:0016746,GO:0016755,GO:0016853,GO:0016860,GO:0016864,GO:0018126,GO:0018193,GO:0018208,GO:0018401,GO:0019221,GO:0019471,GO:0019511,GO:0019538,GO:0019752,GO:0019798,GO:0019899,GO:0022607,GO:0023051,GO:0023052,GO:0031543,GO:0031545,GO:0031974,GO:0032501,GO:0032991,GO:0033554,GO:0034097,GO:0034377,GO:0034378,GO:0034379,GO:0034663,GO:0034976,GO:0035722,GO:0036211,GO:0036293,GO:0036294,GO:0038155,GO:0042221,GO:0042981,GO:0043062,GO:0043067,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043687,GO:0043900,GO:0043902,GO:0043903,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0046596,GO:0046598,GO:0046982,GO:0046983,GO:0048518,GO:0048524,GO:0048583,GO:0050789,GO:0050792,GO:0050794,GO:0050839,GO:0050896,GO:0051213,GO:0051716,GO:0055114,GO:0065003,GO:0065005,GO:0065007,GO:0070013,GO:0070482,GO:0070671,GO:0070887,GO:0071310,GO:0071345,GO:0071349,GO:0071453,GO:0071456,GO:0071704,GO:0071825,GO:0071827,GO:0071840,GO:0071944,GO:0080058,GO:0080134,GO:0080135,GO:0097006,GO:0098552,GO:0140096,GO:1900407,GO:1901564,GO:1901605,GO:1902175,GO:1902494,GO:1902531,GO:1902882,GO:1903201,GO:1903900,GO:1903902,GO:1990204,GO:2001233,GO:2001242	5.3.4.1	ko:K09580	ko04141,map04141	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04131,ko04147	-	-	-	Thioredoxin,Thioredoxin_6
k59_756725_1	177437.HRM2_41160	3.46e-135	401.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,42PRT@68525|delta/epsilon subdivisions,2WIWH@28221|Deltaproteobacteria,2MIPZ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Phosphoenolpyruvate carboxykinase N-terminal domain	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2638	PEPCK_C,PEPCK_N
k59_443452_1	1237149.C900_00574	2.83e-56	186.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes	976|Bacteroidetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_1070066_1	589865.DaAHT2_1282	3.2e-87	269.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2MHY8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
k59_1188117_1	1168065.DOK_12531	2.44e-117	343.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RSHU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	tnpB	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_91602_2	1283300.ATXB01000001_gene1555	9.61e-59	194.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,1S28T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
k59_718276_1	1121439.dsat_1401	1.52e-60	191.0	COG0243@1|root,COG0243@2|Bacteria,1MWPS@1224|Proteobacteria,42QIW@68525|delta/epsilon subdivisions,2WJPY@28221|Deltaproteobacteria,2MB0B@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	molybdopterin oxidoreductase Fe4S4	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,TAT_signal
k59_756763_2	1219080.VEZ01S_08_01430	1.63e-50	179.0	COG4775@1|root,COG4775@2|Bacteria,1R536@1224|Proteobacteria,1RYQ6@1236|Gammaproteobacteria,1Y29N@135623|Vibrionales	135623|Vibrionales	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
k59_1228808_1	272123.Anacy_3210	5.94e-84	272.0	COG0542@1|root,COG0542@2|Bacteria,1G04Z@1117|Cyanobacteria,1HKJQ@1161|Nostocales	1117|Cyanobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_560993_1	1367847.JCM7686_1683	9.38e-45	152.0	COG0412@1|root,COG0412@2|Bacteria,1PKGT@1224|Proteobacteria,2U577@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
k59_1228814_1	439235.Dalk_2765	9.17e-26	108.0	2E769@1|root,331Q7@2|Bacteria,1NEM5@1224|Proteobacteria,42WHJ@68525|delta/epsilon subdivisions,2WS1T@28221|Deltaproteobacteria,2MM54@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1188149_1	670307.HYPDE_24643	7.39e-50	172.0	COG1384@1|root,COG1384@2|Bacteria,1MV32@1224|Proteobacteria,2TQYH@28211|Alphaproteobacteria,3N6KS@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
k59_1148660_1	1340493.JNIF01000003_gene3040	1.3e-25	102.0	COG3293@1|root,COG3293@2|Bacteria,3Y7X8@57723|Acidobacteria	57723|Acidobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
k59_678599_1	985054.JQEZ01000003_gene1728	3.41e-48	165.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TSCF@28211|Alphaproteobacteria,4NBFV@97050|Ruegeria	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K01998,ko:K11960	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
k59_1148670_1	1205680.CAKO01000002_gene2549	1.61e-65	209.0	COG3618@1|root,COG3618@2|Bacteria,1R4T9@1224|Proteobacteria,2TRFM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
k59_1070125_1	1121413.JMKT01000010_gene695	9.22e-103	306.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WMES@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_51564_1	933262.AXAM01000088_gene300	2.52e-95	300.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria,2MHVB@213118|Desulfobacterales	28221|Deltaproteobacteria	J	glycyl-tRNA synthetase, beta	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
k59_1148690_1	443143.GM18_0550	6.35e-57	199.0	COG1010@1|root,COG1492@1|root,COG1010@2|Bacteria,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,42M9K@68525|delta/epsilon subdivisions,2WJ22@28221|Deltaproteobacteria,43S29@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,Aminotran_1_2,CbiA,GATase_3,TP_methylase
k59_795774_1	313603.FB2170_10126	1.06e-59	206.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
k59_130094_1	1894.JOER01000017_gene4799	3.98e-12	67.8	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_600596_1	177437.HRM2_22250	4.35e-68	216.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2MJ0G@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
k59_91739_1	96561.Dole_2208	6e-42	146.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria,2MISR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
k59_91739_2	933262.AXAM01000015_gene87	6.45e-16	73.9	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,2MJWT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
k59_756880_1	765914.ThisiDRAFT_1202	1.66e-34	135.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,1RP08@1236|Gammaproteobacteria,1WX2T@135613|Chromatiales	135613|Chromatiales	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
k59_1148755_1	161528.ED21_17932	6.48e-36	126.0	2CFV6@1|root,32RKG@2|Bacteria,1MZSJ@1224|Proteobacteria,2UDWC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
k59_91771_1	760568.Desku_0440	1.1e-07	54.3	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,261CY@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,AP_endonuc_2
k59_1033517_1	204669.Acid345_2395	6.59e-37	142.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
k59_835326_1	1123261.AXDW01000010_gene439	6.52e-105	317.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1X3B9@135614|Xanthomonadales	135614|Xanthomonadales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
k59_756889_1	717231.Flexsi_0713	2.67e-59	197.0	COG0174@1|root,COG0174@2|Bacteria,2GG7C@200930|Deferribacteres	200930|Deferribacteres	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_756891_1	84531.JMTZ01000039_gene554	4.9e-39	147.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1X39Z@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
k59_286957_1	10181.XP_004873435.1	5.07e-90	264.0	COG1552@1|root,KOG0003@2759|Eukaryota,39ZU5@33154|Opisthokonta,3BPCG@33208|Metazoa,3D67K@33213|Bilateria,48DZE@7711|Chordata,49AU8@7742|Vertebrata,3JGEB@40674|Mammalia,35PWK@314146|Euarchontoglires,4Q559@9989|Rodentia	33208|Metazoa	J	structural constituent of ribosome	UBA52	GO:0000122,GO:0000165,GO:0000184,GO:0000187,GO:0000209,GO:0000715,GO:0000731,GO:0000956,GO:0001666,GO:0001932,GO:0001934,GO:0002181,GO:0002218,GO:0002221,GO:0002224,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0002753,GO:0002755,GO:0002756,GO:0002757,GO:0002758,GO:0002764,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005768,GO:0005783,GO:0005789,GO:0005791,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006294,GO:0006296,GO:0006297,GO:0006301,GO:0006355,GO:0006357,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006464,GO:0006468,GO:0006508,GO:0006511,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006625,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006950,GO:0006974,GO:0006996,GO:0007031,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007249,GO:0007254,GO:0007267,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009628,GO:0009636,GO:0009719,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010008,GO:0010033,GO:0010467,GO:0010468,GO:0010498,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0010942,GO:0012505,GO:0012506,GO:0015031,GO:0015833,GO:0015934,GO:0016020,GO:0016032,GO:0016043,GO:0016055,GO:0016070,GO:0016071,GO:0016192,GO:0016197,GO:0016310,GO:0016567,GO:0016579,GO:0017015,GO:0017085,GO:0018130,GO:0019058,GO:0019068,GO:0019219,GO:0019220,GO:0019221,GO:0019222,GO:0019438,GO:0019439,GO:0019538,GO:0019867,GO:0019941,GO:0019985,GO:0022607,GO:0022625,GO:0022626,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030139,GO:0030163,GO:0030512,GO:0030522,GO:0030659,GO:0030666,GO:0030867,GO:0031090,GO:0031098,GO:0031145,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031347,GO:0031349,GO:0031386,GO:0031399,GO:0031401,GO:0031410,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0031982,GO:0031984,GO:0032147,GO:0032268,GO:0032270,GO:0032446,GO:0032991,GO:0033036,GO:0033365,GO:0033554,GO:0033674,GO:0033683,GO:0034097,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034654,GO:0034655,GO:0035556,GO:0035666,GO:0035872,GO:0036211,GO:0036293,GO:0036294,GO:0036297,GO:0042175,GO:0042221,GO:0042276,GO:0042325,GO:0042327,GO:0042769,GO:0042886,GO:0042981,GO:0043043,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043161,GO:0043170,GO:0043209,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043487,GO:0043488,GO:0043549,GO:0043574,GO:0043603,GO:0043604,GO:0043618,GO:0043620,GO:0043632,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044432,GO:0044433,GO:0044440,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044766,GO:0045047,GO:0045088,GO:0045089,GO:0045184,GO:0045859,GO:0045860,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045937,GO:0045944,GO:0046483,GO:0046700,GO:0046794,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051090,GO:0051091,GO:0051092,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051338,GO:0051347,GO:0051403,GO:0051603,GO:0051606,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0055085,GO:0060255,GO:0060548,GO:0061013,GO:0061024,GO:0061418,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070423,GO:0070482,GO:0070498,GO:0070555,GO:0070646,GO:0070647,GO:0070727,GO:0070848,GO:0070887,GO:0070911,GO:0070972,GO:0070987,GO:0071310,GO:0071345,GO:0071347,GO:0071363,GO:0071453,GO:0071456,GO:0071495,GO:0071559,GO:0071560,GO:0071702,GO:0071704,GO:0071705,GO:0071824,GO:0071840,GO:0071897,GO:0071900,GO:0071902,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0072662,GO:0072663,GO:0075733,GO:0080090,GO:0080134,GO:0090092,GO:0090101,GO:0090150,GO:0090287,GO:0090288,GO:0090304,GO:0090305,GO:0097708,GO:0098552,GO:0098554,GO:0098556,GO:0098562,GO:0098588,GO:0098805,GO:0098827,GO:0198738,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1902531,GO:1902533,GO:1902579,GO:1902679,GO:1902680,GO:1903311,GO:1903506,GO:1903507,GO:1903508,GO:1903844,GO:1903845,GO:1905114,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02927	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L40e,ubiquitin
k59_130177_1	316058.RPB_1643	3.34e-60	198.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,2TT4B@28211|Alphaproteobacteria,3JWYY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_835353_1	187272.Mlg_1887	1.67e-30	111.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1WY2N@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
k59_405658_1	506534.Rhein_1384	8.26e-83	253.0	COG3186@1|root,COG3186@2|Bacteria,1MU29@1224|Proteobacteria,1RQBJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Phenylalanine-4-hydroxylase	phhA	GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
k59_600674_1	502025.Hoch_3702	7.22e-63	217.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2YU45@29|Myxococcales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
k59_874461_1	713586.KB900536_gene209	6.31e-74	235.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RNVP@1236|Gammaproteobacteria,1WXS3@135613|Chromatiales	135613|Chromatiales	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.8.2.3	ko:K17229	ko00920,ko01120,map00920,map01120	-	R09499	-	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
k59_51671_2	163164.WD_0741	3.66e-85	263.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,47F2K@766|Rickettsiales	766|Rickettsiales	C	COG1294 Cytochrome bd-type quinol oxidase, subunit 2	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
k59_561155_2	519989.ECTPHS_02199	5.6e-41	140.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1WYG6@135613|Chromatiales	135613|Chromatiales	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_600691_1	883.DvMF_0070	7.41e-75	235.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,42MZU@68525|delta/epsilon subdivisions,2WKKU@28221|Deltaproteobacteria,2M7X4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
k59_130208_1	1265505.ATUG01000001_gene2967	3.73e-67	214.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,43BDC@68525|delta/epsilon subdivisions,2WK43@28221|Deltaproteobacteria,2MHPC@213118|Desulfobacterales	28221|Deltaproteobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	aapJ	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
k59_639563_1	314285.KT71_06252	8.29e-29	119.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S876@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1070258_1	1121405.dsmv_3691	6.19e-82	254.0	COG3547@1|root,COG3547@2|Bacteria,1NP2U@1224|Proteobacteria,43A5Q@68525|delta/epsilon subdivisions,2X2AM@28221|Deltaproteobacteria,2MPDW@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_795896_1	1236541.BALL01000038_gene3759	1.32e-73	236.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,1RMQC@1236|Gammaproteobacteria,2QB5A@267890|Shewanellaceae	1236|Gammaproteobacteria	F	Amidohydrolase family	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
k59_795905_1	1304275.C41B8_14975	2.9e-38	145.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	ABC transporter substrate-binding protein	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
k59_718472_1	1121405.dsmv_3263	2.34e-93	297.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,2MHQG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_482925_1	1395571.TMS3_0118225	2.53e-20	90.9	COG1999@1|root,COG1999@2|Bacteria,1REUE@1224|Proteobacteria,1SBGQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
k59_1033633_1	56780.SYN_01358	1.51e-44	159.0	COG0317@1|root,COG0317@2|Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	1.1.1.3,2.7.6.5,3.1.7.2	ko:K00003,ko:K01139	ko00230,ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R00336,R00429,R01773,R01775	RC00002,RC00078,RC00087	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	HD_4,HTH_3,RelA_SpoT
k59_835404_2	1187848.AJYQ01000003_gene410	2.85e-102	312.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGA@1236|Gammaproteobacteria,1XXNF@135623|Vibrionales	135623|Vibrionales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_634232_1	1443665.JACA01000053_gene3261	1.27e-82	275.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2YIFW@290174|Aquimarina	976|Bacteroidetes	S	BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
k59_790679_1	382245.ASA_0292	1.83e-41	151.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1Y3Y0@135624|Aeromonadales	135624|Aeromonadales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_790679_2	1027273.GZ77_18725	1.87e-55	183.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1XH22@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
k59_7300_1	314285.KT71_08620	1.06e-47	164.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1J9WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
k59_673182_2	316067.Geob_1016	5.66e-29	111.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,43T2N@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
k59_399219_2	706587.Desti_0193	4.11e-23	92.0	COG0607@1|root,COG0607@2|Bacteria,1NBYS@1224|Proteobacteria,42VJA@68525|delta/epsilon subdivisions,2WS01@28221|Deltaproteobacteria,2MSAI@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_555596_1	264732.Moth_0561	7.68e-07	55.8	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,42F3Z@68295|Thermoanaerobacterales	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
k59_360151_1	394221.Mmar10_0249	3.68e-39	147.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,2TS28@28211|Alphaproteobacteria,43W98@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_7320_1	1042377.AFPJ01000051_gene87	1.39e-89	278.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,46DHJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Sulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
k59_868825_1	990285.RGCCGE502_08645	1.26e-80	249.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,4B7TE@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	metal ion binding	MA20_22850	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
k59_164016_1	1237149.C900_02654	5.96e-39	146.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47TV8@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_712007_1	396588.Tgr7_2456	6.27e-21	92.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
k59_399247_1	933262.AXAM01000017_gene3141	2.33e-56	184.0	COG1150@1|root,COG1150@2|Bacteria,1QWNB@1224|Proteobacteria,43BTA@68525|delta/epsilon subdivisions,2X741@28221|Deltaproteobacteria,2MI1V@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
k59_399247_2	335543.Sfum_1970	4.05e-63	200.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,42MVW@68525|delta/epsilon subdivisions,2WKKC@28221|Deltaproteobacteria,2MQGV@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Oxidoreductase NAD-binding domain	hdrF	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
k59_164021_1	1121943.KB900012_gene4060	7.7e-72	224.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RR8F@1236|Gammaproteobacteria,1XRIQ@135619|Oceanospirillales	135619|Oceanospirillales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve_3
k59_516704_1	1123228.AUIH01000002_gene1565	9.17e-133	395.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1XH25@135619|Oceanospirillales	135619|Oceanospirillales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
k59_516704_2	1122134.KB893650_gene157	1.29e-15	71.2	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1XKMB@135619|Oceanospirillales	135619|Oceanospirillales	K	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters	fis	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
k59_987031_1	391615.ABSJ01000037_gene896	3.95e-20	87.4	COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0848 Biopolymer transport protein	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
k59_987031_2	396588.Tgr7_0539	1.02e-55	181.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1X07Q@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
k59_360198_1	1049564.TevJSym_aq00690	1.96e-27	109.0	COG4659@1|root,COG4659@2|Bacteria,1REZV@1224|Proteobacteria,1T054@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
k59_634292_1	1117319.PSPO_00842	5.97e-43	162.0	COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria,1RTPH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
k59_594886_1	1238182.C882_4240	1.74e-26	102.0	COG1320@1|root,COG1320@2|Bacteria,1N75I@1224|Proteobacteria,2UETR@28211|Alphaproteobacteria,2JU90@204441|Rhodospirillales	204441|Rhodospirillales	P	Na+/H+ antiporter subunit	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
k59_594886_2	318167.Sfri_2282	3.28e-37	127.0	COG2212@1|root,COG2212@2|Bacteria,1N6VV@1224|Proteobacteria,1SE40@1236|Gammaproteobacteria,2QCE2@267890|Shewanellaceae	1236|Gammaproteobacteria	P	PFAM multiple resistance and pH regulation protein F	mnhF	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
k59_594886_3	876044.IMCC3088_2036	1.27e-40	139.0	COG1863@1|root,COG1863@2|Bacteria	2|Bacteria	P	multisubunit Na H antiporter MnhE subunit	mnhE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
k59_202828_1	472759.Nhal_3898	2.25e-87	266.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria,1WW4G@135613|Chromatiales	135613|Chromatiales	P	PFAM CBS domain	-	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
k59_437962_1	1121405.dsmv_2418	1.45e-81	248.0	COG0600@1|root,COG0600@2|Bacteria,1NDW4@1224|Proteobacteria,42PPI@68525|delta/epsilon subdivisions,2WMA3@28221|Deltaproteobacteria,2MI72@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
k59_399293_2	880072.Desac_2120	4.8e-19	79.0	2ES6V@1|root,33JRM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1182904_1	335543.Sfum_0458	2.59e-95	293.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2MR53@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
k59_437979_1	1123242.JH636435_gene2725	1.03e-29	117.0	COG1606@1|root,COG1606@2|Bacteria,2IXSS@203682|Planctomycetes	203682|Planctomycetes	S	of the PP-loop superfamily	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
k59_868885_1	237368.SCABRO_03829	8.73e-43	147.0	COG1226@1|root,32Y28@2|Bacteria,2J0V4@203682|Planctomycetes	203682|Planctomycetes	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
k59_673292_1	269482.Bcep1808_2930	1.83e-35	138.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2VHCS@28216|Betaproteobacteria,1K1R9@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
k59_712079_1	292415.Tbd_0739	2.76e-54	190.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,1KR9X@119069|Hydrogenophilales	1224|Proteobacteria	V	ABC transporter transmembrane region	atmA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Response_reg
k59_594943_1	880072.Desac_1217	1.27e-64	217.0	COG0466@1|root,COG0466@2|Bacteria,1R6HF@1224|Proteobacteria,42QHZ@68525|delta/epsilon subdivisions,2WJNZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Response regulator receiver	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,Lon_C,Response_reg
k59_673320_1	1307759.JOMJ01000004_gene3083	1.4e-74	239.0	COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,42NDR@68525|delta/epsilon subdivisions,2WJQ4@28221|Deltaproteobacteria,2M9X7@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	-	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
k59_673327_1	670307.HYPDE_29048	1.17e-61	201.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,3N6EI@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
k59_477349_1	1121374.KB891575_gene1527	1.33e-70	231.0	COG0591@1|root,COG0591@2|Bacteria,1R86J@1224|Proteobacteria,1S1QC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
k59_1104417_1	1121405.dsmv_3379	8.51e-45	146.0	COG0695@1|root,COG0695@2|Bacteria,1NAZM@1224|Proteobacteria,42VIA@68525|delta/epsilon subdivisions,2WR8X@28221|Deltaproteobacteria,2MKPI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM Glutaredoxin	-	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
k59_1104417_2	525897.Dbac_0077	6.81e-35	121.0	COG4802@1|root,COG4802@2|Bacteria,1RI70@1224|Proteobacteria,42SXJ@68525|delta/epsilon subdivisions,2WP19@28221|Deltaproteobacteria,2MBWH@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM ferredoxin thioredoxin reductase beta	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
k59_947481_1	157783.LK03_19640	8.58e-107	320.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
k59_86198_1	1282876.BAOK01000002_gene906	5.3e-12	71.6	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2TUW3@28211|Alphaproteobacteria,4BS4U@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Phospholipase_D-nuclease N-terminal	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
k59_281427_1	1121028.ARQE01000002_gene2213	3.94e-100	301.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2TSHM@28211|Alphaproteobacteria,2PJA0@255475|Aurantimonadaceae	28211|Alphaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
k59_673381_1	547163.BN979_00632	8.66e-12	69.7	COG0687@1|root,COG0687@2|Bacteria,2GJM8@201174|Actinobacteria,23701@1762|Mycobacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
k59_164131_1	1121447.JONL01000001_gene465	2.44e-31	127.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2X7E0@28221|Deltaproteobacteria,2MHE4@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_320549_1	765698.Mesci_3912	2.25e-10	61.2	COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,2U9DZ@28211|Alphaproteobacteria,43K5R@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	MA20_01310	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
k59_673405_1	998674.ATTE01000001_gene293	5.24e-87	281.0	COG0749@1|root,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,45ZUW@72273|Thiotrichales	72273|Thiotrichales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
k59_516862_1	870187.Thini_3423	1.72e-61	204.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,45ZW7@72273|Thiotrichales	72273|Thiotrichales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_790872_1	323261.Noc_0897	8.69e-62	207.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,1WXRW@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
k59_829860_1	986075.CathTA2_2464	1.08e-50	176.0	COG3547@1|root,COG3547@2|Bacteria,1TRSB@1239|Firmicutes,4HDPK@91061|Bacilli	91061|Bacilli	L	PFAM transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_7479_1	745014.OMB55_00012360	4.02e-70	238.0	COG1629@1|root,COG1629@2|Bacteria,1MV8W@1224|Proteobacteria,1RQEQ@1236|Gammaproteobacteria,1J4HT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_868992_1	27679.XP_003933165.1	2.12e-95	286.0	KOG1560@1|root,KOG1560@2759|Eukaryota,3906S@33154|Opisthokonta,3BAGT@33208|Metazoa,3CUH1@33213|Bilateria,48AD8@7711|Chordata,495SB@7742|Vertebrata,3JANP@40674|Mammalia,35NX6@314146|Euarchontoglires,4MBTU@9443|Primates	33208|Metazoa	J	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2 GTP methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression	EIF3H	GO:0001944,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005852,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0008135,GO:0008150,GO:0008152,GO:0008593,GO:0009058,GO:0009059,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0010646,GO:0010647,GO:0019222,GO:0019538,GO:0023051,GO:0023056,GO:0031323,GO:0031326,GO:0032268,GO:0032501,GO:0032502,GO:0032991,GO:0034248,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045747,GO:0048513,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0048880,GO:0048882,GO:0048925,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0060322,GO:0065007,GO:0071541,GO:0071704,GO:0072358,GO:0072359,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	ko:K03247	ko03013,ko05162,map03013,map05162	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	JAB
k59_829874_1	3988.XP_002528161.1	2.7e-10	64.7	COG3158@1|root,2QPSA@2759|Eukaryota,37JCM@33090|Viridiplantae,3GAU4@35493|Streptophyta,4JHI7@91835|fabids	35493|Streptophyta	P	Potassium transporter	-	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
k59_164164_1	1382303.JPOM01000001_gene200	1.81e-17	81.3	COG1028@1|root,COG1028@2|Bacteria,1RF8S@1224|Proteobacteria,2TWEU@28211|Alphaproteobacteria,2KI9R@204458|Caulobacterales	204458|Caulobacterales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
k59_164164_2	1245471.PCA10_29460	8.12e-42	152.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,1RQD3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	fadD6	-	6.2.1.48	ko:K00666,ko:K02182,ko:K13776	ko00281,map00281	-	R08088	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_1026295_1	768671.ThimaDRAFT_0872	1.43e-26	114.0	COG1289@1|root,COG1289@2|Bacteria,1QJEM@1224|Proteobacteria,1SMXK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Aromatic acid exporter family member 1	VPA1578	-	-	-	-	-	-	-	-	-	-	-	FUSC
k59_829882_1	384765.SIAM614_02581	1.34e-93	291.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_987196_2	9694.XP_007097512.1	9.3e-09	56.2	KOG1192@1|root,KOG1192@2759|Eukaryota,38HD1@33154|Opisthokonta,3BHH3@33208|Metazoa,3CW3N@33213|Bilateria,48BS3@7711|Chordata,4967X@7742|Vertebrata,3JAX7@40674|Mammalia,3EQI3@33554|Carnivora	33208|Metazoa	CG	UDP-glucuronosyltransferase	UGT3A2	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0008194,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0012505,GO:0014070,GO:0015020,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0031984,GO:0032870,GO:0032991,GO:0033594,GO:0033595,GO:0035690,GO:0042175,GO:0042221,GO:0042493,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043541,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071407,GO:0071412,GO:0071413,GO:0071495,GO:0080184,GO:0097327,GO:0098796,GO:0098827,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1905546	2.4.1.17	ko:K00699	ko00040,ko00053,ko00140,ko00830,ko00860,ko00980,ko00982,ko00983,ko01100,ko01110,ko05204,map00040,map00053,map00140,map00830,map00860,map00980,map00982,map00983,map01100,map01110,map05204	M00014,M00129	R01383,R02358,R02389,R02478,R02502,R02902,R03091,R04352,R04353,R04354,R04683,R07106,R08259,R08261,R08262,R08263,R08615,R09426,R09427,R09428	RC00005,RC00033,RC00049,RC00059,RC00078,RC00171,RC00397,RC00523,RC00529,RC00708,RC02748	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT1	-	UDPGT
k59_751708_1	304371.MCP_0432	1.56e-71	237.0	COG0433@1|root,arCOG09167@1|root,arCOG00280@2157|Archaea,arCOG00286@2157|Archaea,arCOG09167@2157|Archaea	2157|Archaea	P	protein kinase activity	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
k59_164191_1	27679.XP_010346177.1	3.15e-188	535.0	COG0166@1|root,KOG2446@2759|Eukaryota,38EWT@33154|Opisthokonta,3B93W@33208|Metazoa,3CUZG@33213|Bilateria,489XR@7711|Chordata,48XPM@7742|Vertebrata,3J7QY@40674|Mammalia,358VD@314146|Euarchontoglires,4M8ZW@9443|Primates	33208|Metazoa	G	glucose-6-phosphate isomerase activity	GPI	GO:0001701,GO:0001704,GO:0001707,GO:0001775,GO:0002252,GO:0002262,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002637,GO:0002639,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002791,GO:0002793,GO:0003008,GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0005929,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006959,GO:0007275,GO:0007369,GO:0007498,GO:0007599,GO:0007610,GO:0007611,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009410,GO:0009435,GO:0009438,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009888,GO:0009892,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0010466,GO:0010594,GO:0010595,GO:0010605,GO:0010632,GO:0010634,GO:0010941,GO:0010951,GO:0012505,GO:0014070,GO:0014072,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016192,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0016866,GO:0017144,GO:0018130,GO:0019222,GO:0019242,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0019899,GO:0030141,GO:0030162,GO:0030246,GO:0030334,GO:0030335,GO:0031090,GO:0031253,GO:0031323,GO:0031324,GO:0031410,GO:0031625,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032355,GO:0032501,GO:0032502,GO:0032570,GO:0032787,GO:0032879,GO:0032880,GO:0032940,GO:0033500,GO:0033574,GO:0033993,GO:0034101,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034774,GO:0035902,GO:0035994,GO:0036094,GO:0036230,GO:0040012,GO:0040017,GO:0042119,GO:0042180,GO:0042181,GO:0042221,GO:0042493,GO:0042592,GO:0042593,GO:0042866,GO:0042981,GO:0042995,GO:0043005,GO:0043009,GO:0043066,GO:0043067,GO:0043069,GO:0043086,GO:0043154,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043278,GO:0043279,GO:0043281,GO:0043299,GO:0043312,GO:0043436,GO:0043523,GO:0043524,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044433,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0045861,GO:0046031,GO:0046034,GO:0046184,GO:0046185,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046686,GO:0046700,GO:0046903,GO:0046939,GO:0048029,GO:0048332,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048598,GO:0048646,GO:0048729,GO:0048856,GO:0048872,GO:0048878,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050877,GO:0050878,GO:0050890,GO:0050896,GO:0051023,GO:0051024,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051156,GO:0051171,GO:0051172,GO:0051179,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051270,GO:0051272,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060170,GO:0060205,GO:0060255,GO:0060359,GO:0060548,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0071704,GO:0071944,GO:0072330,GO:0072347,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097458,GO:0097708,GO:0098588,GO:0098590,GO:0099503,GO:0101002,GO:0120025,GO:0120038,GO:1901135,GO:1901137,GO:1901214,GO:1901215,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901654,GO:1901698,GO:1901700,GO:1903530,GO:1903532,GO:1904813,GO:1904951,GO:2000116,GO:2000117,GO:2000145,GO:2000147	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
k59_947576_1	525897.Dbac_0975	9.08e-63	214.0	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFY@68525|delta/epsilon subdivisions,2WKC0@28221|Deltaproteobacteria,2M7TX@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,HisKA,PAS_8,PAS_9,sCache_3_2
k59_595086_1	396588.Tgr7_0623	8.5e-77	241.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RRCR@1236|Gammaproteobacteria,1WYMQ@135613|Chromatiales	135613|Chromatiales	K	Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
k59_516932_1	207954.MED92_08386	9.47e-89	266.0	COG0678@1|root,COG0695@1|root,COG0678@2|Bacteria,COG0695@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,1XI2I@135619|Oceanospirillales	135619|Oceanospirillales	O	Peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin,Redoxin
k59_46213_1	2002.JOEQ01000012_gene5833	1.47e-24	108.0	COG4447@1|root,COG5297@1|root,COG4447@2|Bacteria,COG5297@2|Bacteria,2GMQN@201174|Actinobacteria,4EIBY@85012|Streptosporangiales	201174|Actinobacteria	G	Cellulase N-terminal ig-like domain	cel1	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,CBM_4_9,CelD_N,Glyco_hydro_9
k59_86315_1	1121403.AUCV01000056_gene3023	9.93e-42	156.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
k59_987230_1	426114.THI_0135	7.21e-273	750.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria,1KJRD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
k59_438199_1	1380380.JIAX01000010_gene127	1.65e-31	125.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	mechanosensitive ion channel	MA20_40450	-	-	-	-	-	-	-	-	-	-	-	MS_channel
k59_555883_1	1184607.AUCHE_16_01290	3.69e-29	117.0	COG0031@1|root,COG0031@2|Bacteria,2GJGN@201174|Actinobacteria,4F7D7@85018|Dermatophilaceae	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.3.1.263	ko:K21400	-	-	-	-	ko00000,ko01000	-	-	-	PALP
k59_949894_1	671143.DAMO_2651	2.27e-129	389.0	COG0021@1|root,COG0021@2|Bacteria,2NS3T@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
k59_244842_1	1049564.TevJSym_ab00170	1.05e-08	57.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,1S03J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
k59_949901_1	1231190.NA8A_03990	9.34e-20	89.4	29CEM@1|root,2ZZD2@2|Bacteria,1RB3W@1224|Proteobacteria,2U9X1@28211|Alphaproteobacteria,43QV6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1145789_1	439235.Dalk_0873	8.93e-35	139.0	COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X756@28221|Deltaproteobacteria,2MPM5@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,PocR,Response_reg
k59_48941_1	1121918.ARWE01000001_gene239	5.14e-40	146.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,43SB5@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III subunits gamma and tau domain III	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
k59_675656_1	631362.Thi970DRAFT_01198	6.38e-29	119.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1WVXZ@135613|Chromatiales	135613|Chromatiales	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
k59_229126_1	391587.KAOT1_14757	5.01e-84	270.0	COG0339@1|root,COG0339@2|Bacteria,4NFYA@976|Bacteroidetes,1HY0G@117743|Flavobacteriia	976|Bacteroidetes	E	Peptidase family M3	-	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
k59_930904_1	335543.Sfum_0854	2.28e-39	145.0	COG3290@1|root,COG3852@1|root,COG3290@2|Bacteria,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,43BPS@68525|delta/epsilon subdivisions,2X710@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Signal transduction histidine kinase, nitrogen specific	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
k59_930905_1	1265505.ATUG01000002_gene1690	1.67e-18	82.8	COG1392@1|root,COG1392@2|Bacteria	2|Bacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
k59_930905_2	459495.SPLC1_S201490	4.15e-24	102.0	COG0306@1|root,COG0306@2|Bacteria,1G13U@1117|Cyanobacteria	1117|Cyanobacteria	P	PFAM phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
k59_461555_1	160488.PP_1753	1.45e-46	163.0	COG0697@1|root,COG0697@2|Bacteria,1PGSE@1224|Proteobacteria,1RMZY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	yhbE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	EamA
k59_1127908_1	96561.Dole_1585	3.65e-43	155.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,2MHW2@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
k59_1206662_1	745411.B3C1_14223	7.06e-36	132.0	COG0515@1|root,COG0515@2|Bacteria,1QUW7@1224|Proteobacteria,1T23C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
k59_930931_1	1121405.dsmv_0405	2e-98	302.0	COG1183@1|root,COG1183@2|Bacteria,1MYK9@1224|Proteobacteria,42RFD@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA2	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
k59_930941_1	439235.Dalk_4615	2.13e-32	128.0	COG0582@1|root,COG0582@2|Bacteria,1R3T2@1224|Proteobacteria,42PPE@68525|delta/epsilon subdivisions,2WKWN@28221|Deltaproteobacteria,2MJ75@213118|Desulfobacterales	28221|Deltaproteobacteria	L	'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
k59_429347_1	1161401.ASJA01000010_gene1397	5.38e-34	132.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,43Z0S@69657|Hyphomonadaceae	28211|Alphaproteobacteria	KL	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
k59_461596_1	187272.Mlg_1967	1.74e-119	351.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
k59_429348_1	1286106.MPL1_04962	8.51e-73	243.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,45ZRC@72273|Thiotrichales	72273|Thiotrichales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
k59_69120_1	1304885.AUEY01000091_gene1630	1.26e-87	293.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2X7E0@28221|Deltaproteobacteria,2MITZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3
k59_30317_1	236097.ADG881_83	1.57e-59	199.0	COG3170@1|root,COG3170@2|Bacteria,1QXKE@1224|Proteobacteria,1T3DZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_656750_1	395493.BegalDRAFT_0480	2.09e-05	48.1	2DNTZ@1|root,32Z4F@2|Bacteria,1NA30@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
k59_775163_1	279714.FuraDRAFT_1443	2.54e-07	50.1	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2VRQ3@28216|Betaproteobacteria,2KR3Y@206351|Neisseriales	206351|Neisseriales	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
k59_775163_2	1453501.JELR01000002_gene1194	9.32e-41	153.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,46544@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
k59_543789_1	1163617.SCD_n01209	8e-108	337.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_619132_1	1205753.A989_05402	1.63e-38	136.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,1T042@1236|Gammaproteobacteria,1X4RF@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
k59_229212_2	1499967.BAYZ01000182_gene4431	1.63e-68	224.0	arCOG09146@1|root,2ZPZ6@2|Bacteria	2|Bacteria	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_461640_1	649638.Trad_0386	2.93e-53	192.0	COG2902@1|root,COG2902@2|Bacteria	2|Bacteria	E	glutamate catabolic process to 2-oxoglutarate	gdhB	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH,ELFV_dehydrog
k59_1087898_1	1123400.KB904758_gene2274	1.02e-87	272.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,45ZP0@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
k59_186638_1	324057.Pjdr2_2422	2.22e-05	47.8	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,26RKI@186822|Paenibacillaceae	91061|Bacilli	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
k59_1087917_1	1121413.JMKT01000009_gene2201	8.15e-09	56.2	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42M9D@68525|delta/epsilon subdivisions,2WJ43@28221|Deltaproteobacteria,2M8UY@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
k59_1087917_2	555779.Dthio_PD1173	1.07e-49	165.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M6H@68525|delta/epsilon subdivisions,2WNDN@28221|Deltaproteobacteria,2M82Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin	-	-	-	ko:K04014,ko:K08358	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Fer4_11,Fer4_3,Fer4_4
k59_229251_1	595494.Tola_2334	8.82e-17	80.9	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1Y4DY@135624|Aeromonadales	135624|Aeromonadales	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
k59_229251_2	105559.Nwat_1853	6.19e-42	148.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1WX3R@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
k59_853244_2	526222.Desal_3404	2.37e-46	156.0	COG0607@1|root,COG0607@2|Bacteria,1RA3A@1224|Proteobacteria,42QNH@68525|delta/epsilon subdivisions,2WMPB@28221|Deltaproteobacteria,2MACC@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MauE,Rhodanese
k59_1167454_2	748449.Halha_0393	1.13e-40	142.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,3WBXQ@53433|Halanaerobiales	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_853253_1	1121405.dsmv_1070	1.5e-84	261.0	COG3839@1|root,COG3839@2|Bacteria,1PA89@1224|Proteobacteria,42PEJ@68525|delta/epsilon subdivisions,2WJ1D@28221|Deltaproteobacteria,2MIHS@213118|Desulfobacterales	28221|Deltaproteobacteria	G	ABC transporter	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
k59_972184_1	118797.XP_007470109.1	2.01e-87	257.0	COG1383@1|root,KOG0187@2759|Eukaryota,3A23Y@33154|Opisthokonta,3BPFC@33208|Metazoa,3D6DC@33213|Bilateria,48DXR@7711|Chordata,49AT4@7742|Vertebrata,3JGIG@40674|Mammalia,4J597@91561|Cetartiodactyla	33208|Metazoa	J	Ribosomal protein S17	RPS17	GO:0000028,GO:0002262,GO:0002376,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005791,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0012505,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030867,GO:0031090,GO:0031984,GO:0032991,GO:0034101,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042175,GO:0042254,GO:0042255,GO:0042274,GO:0042592,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048872,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0098552,GO:0098554,GO:0098556,GO:0098562,GO:0098588,GO:0098827,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02962	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17e
k59_30434_1	880072.Desac_1215	3.6e-68	223.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MR8@68525|delta/epsilon subdivisions,2WIUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
k59_385207_1	948106.AWZT01000037_gene1765	2.95e-27	112.0	COG1172@1|root,COG1172@2|Bacteria,1MUM6@1224|Proteobacteria,2VKCM@28216|Betaproteobacteria,1JZRR@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
k59_30453_1	861299.J421_0531	1.21e-54	193.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
k59_931077_1	439235.Dalk_1463	1.31e-161	462.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1RJT0@1224|Proteobacteria,43CRQ@68525|delta/epsilon subdivisions,2X7ZB@28221|Deltaproteobacteria,2MPB2@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
k59_1128061_1	251229.Chro_5533	1.24e-18	90.9	COG0642@1|root,COG2202@1|root,COG3437@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,3VM5Q@52604|Pleurocapsales	1117|Cyanobacteria	KT	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
k59_69265_2	1201293.AKXQ01000026_gene1526	6.95e-09	60.8	COG2199@1|root,COG2703@1|root,COG2770@1|root,COG2703@2|Bacteria,COG2770@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1SZAB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hemerythrin,NIT
k59_305648_1	760142.Hipma_0529	7.38e-77	249.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,2M6Q5@213113|Desulfurellales	28221|Deltaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
k59_429520_1	485916.Dtox_0091	6.18e-58	202.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,24C4K@186801|Clostridia	186801|Clostridia	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
k59_972251_2	1121405.dsmv_2791	6.32e-80	249.0	COG1533@1|root,COG1533@2|Bacteria,1NWJ9@1224|Proteobacteria,42P30@68525|delta/epsilon subdivisions,2WIPV@28221|Deltaproteobacteria,2MHKC@213118|Desulfobacterales	28221|Deltaproteobacteria	L	radical SAM domain protein	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_385270_1	991905.SL003B_4172	1.29e-53	182.0	COG4645@1|root,COG4645@2|Bacteria,1PI9Q@1224|Proteobacteria,2U1C7@28211|Alphaproteobacteria,4BPA6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	OpgC protein	opgC	-	-	-	-	-	-	-	-	-	-	-	OpgC_C
k59_1015378_1	316057.RPD_2443	1.05e-28	115.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2U0K2@28211|Alphaproteobacteria,3JSWS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
k59_543958_1	1227499.C493_21511	3e-38	143.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,23U1F@183963|Halobacteria	183963|Halobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
k59_385310_2	1117647.M5M_12420	5.25e-67	210.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,1J5X6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0241 Histidinol phosphatase and related phosphatases	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iJN746.PP_0059	Hydrolase_like
k59_972288_1	485916.Dtox_1820	3.19e-76	240.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,2644N@186807|Peptococcaceae	186801|Clostridia	L	Group II intron, maturase-specific domain	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
k59_307545_2	1266914.ATUK01000011_gene2351	5.44e-18	81.3	COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
k59_346813_1	1232410.KI421421_gene3446	2.64e-88	273.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,42TEX@68525|delta/epsilon subdivisions,2WPG8@28221|Deltaproteobacteria,43T5H@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_974172_1	983545.Glaag_2327	1.01e-103	336.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D9@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_621199_1	1382304.JNIL01000001_gene2503	1.9e-61	208.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,4HAP3@91061|Bacilli,278T1@186823|Alicyclobacillaceae	91061|Bacilli	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cbiET	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	Methyltransf_18,PCMT,TP_methylase
k59_699006_1	861299.J421_1340	9.57e-31	124.0	COG0312@1|root,COG0312@2|Bacteria,1ZSUE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD,TAT_signal
k59_1130085_1	880072.Desac_1867	0.000259	48.9	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2MQD2@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
k59_895023_1	765913.ThidrDRAFT_1005	8.29e-88	266.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,1RNTH@1236|Gammaproteobacteria,1WX4V@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
k59_307625_1	177437.HRM2_15110	3.45e-89	274.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2WM27@28221|Deltaproteobacteria,2MJRK@213118|Desulfobacterales	28221|Deltaproteobacteria	C	cytochrome c oxidase	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
k59_268800_1	61622.XP_010386983.1	1.52e-131	400.0	KOG1076@1|root,KOG1076@2759|Eukaryota,38EZF@33154|Opisthokonta,3BBRU@33208|Metazoa,3CRH9@33213|Bilateria,4845X@7711|Chordata,48YVK@7742|Vertebrata,3J5TD@40674|Mammalia,35KZ6@314146|Euarchontoglires,4MH0U@9443|Primates,362E6@314294|Cercopithecoidea	33208|Metazoa	J	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2 GTP methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression	EIF3C	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005852,GO:0006412,GO:0006413,GO:0006417,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031369,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065009,GO:0071541,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902415,GO:1902416,GO:1905214,GO:1905216,GO:2000112	-	ko:K03252	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	PCI,eIF-3c_N
k59_463694_1	886293.Sinac_0967	3.98e-61	212.0	COG0841@1|root,COG0841@2|Bacteria,2IX3P@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_387293_1	1121405.dsmv_3773	1.83e-61	211.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,42NY6@68525|delta/epsilon subdivisions,2WJSE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_1052612_1	1094508.Tsac_0635	1.48e-73	226.0	COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,249EP@186801|Clostridia,42FGP@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
k59_621256_1	9606.ENSP00000262105	1.54e-98	309.0	COG1241@1|root,KOG0478@2759|Eukaryota,38D4R@33154|Opisthokonta,3B9WH@33208|Metazoa,3CSX5@33213|Bilateria,4854K@7711|Chordata,4906I@7742|Vertebrata,3JAR2@40674|Mammalia,35P8R@314146|Euarchontoglires,4MKJH@9443|Primates,4N5GJ@9604|Hominidae	33208|Metazoa	L	Minichromosome maintenance complex component 4	MCM4	GO:0000003,GO:0000082,GO:0000226,GO:0000278,GO:0000785,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006275,GO:0006725,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007275,GO:0007399,GO:0007548,GO:0008150,GO:0008152,GO:0008406,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022414,GO:0030174,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032392,GO:0032501,GO:0032502,GO:0032508,GO:0032991,GO:0034641,GO:0034645,GO:0040011,GO:0042555,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0045137,GO:0046483,GO:0048513,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0051276,GO:0060255,GO:0061458,GO:0065007,GO:0070013,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1902850,GO:1903047,GO:2000112	3.6.4.12	ko:K02212	ko03030,ko04110,ko04111,ko04113,map03030,map04110,map04111,map04113	M00285	-	-	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	MCM,MCM_N,MCM_OB
k59_1052616_1	128390.XP_009470426.1	2.56e-93	283.0	COG5277@1|root,KOG0677@2759|Eukaryota,38C7E@33154|Opisthokonta,3BE2H@33208|Metazoa,3CS7E@33213|Bilateria,4844A@7711|Chordata,48ZWV@7742|Vertebrata,4GHVH@8782|Aves	33208|Metazoa	Z	actin-related protein 2	ACTR2	GO:0000003,GO:0000280,GO:0000323,GO:0000902,GO:0000910,GO:0001667,GO:0001775,GO:0002009,GO:0002102,GO:0002252,GO:0002253,GO:0002262,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002429,GO:0002431,GO:0002433,GO:0002443,GO:0002444,GO:0002446,GO:0002520,GO:0002682,GO:0002684,GO:0002757,GO:0002764,GO:0002768,GO:0003008,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005856,GO:0005884,GO:0005885,GO:0005938,GO:0006810,GO:0006887,GO:0006897,GO:0006909,GO:0006928,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007018,GO:0007049,GO:0007059,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007369,GO:0007399,GO:0007610,GO:0007611,GO:0007612,GO:0008064,GO:0008092,GO:0008150,GO:0008306,GO:0008356,GO:0008582,GO:0009636,GO:0009653,GO:0009719,GO:0009790,GO:0009888,GO:0009987,GO:0010033,GO:0010243,GO:0010631,GO:0010638,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0012505,GO:0014069,GO:0014070,GO:0015629,GO:0016043,GO:0016192,GO:0016331,GO:0016344,GO:0016477,GO:0016482,GO:0022008,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0023052,GO:0030027,GO:0030029,GO:0030030,GO:0030031,GO:0030036,GO:0030097,GO:0030099,GO:0030141,GO:0030154,GO:0030218,GO:0030478,GO:0030832,GO:0030833,GO:0030838,GO:0030863,GO:0030864,GO:0031252,GO:0031334,GO:0031344,GO:0031346,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032271,GO:0032273,GO:0032279,GO:0032501,GO:0032502,GO:0032535,GO:0032940,GO:0032956,GO:0032970,GO:0032989,GO:0032991,GO:0033043,GO:0033206,GO:0034097,GO:0034101,GO:0034314,GO:0034341,GO:0034774,GO:0035162,GO:0035578,GO:0035902,GO:0035983,GO:0035984,GO:0036230,GO:0038093,GO:0038094,GO:0038096,GO:0040008,GO:0040011,GO:0042119,GO:0042221,GO:0042493,GO:0042582,GO:0042592,GO:0042995,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043299,GO:0043312,GO:0044085,GO:0044087,GO:0044089,GO:0044422,GO:0044424,GO:0044430,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044448,GO:0044456,GO:0044464,GO:0044782,GO:0045010,GO:0045055,GO:0045087,GO:0045132,GO:0045202,GO:0045321,GO:0045471,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045887,GO:0045927,GO:0046677,GO:0046903,GO:0046907,GO:0048013,GO:0048285,GO:0048513,GO:0048518,GO:0048522,GO:0048534,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048638,GO:0048639,GO:0048699,GO:0048729,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0048870,GO:0048872,GO:0050000,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050808,GO:0050877,GO:0050890,GO:0050896,GO:0051094,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051301,GO:0051303,GO:0051305,GO:0051321,GO:0051489,GO:0051493,GO:0051495,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0051674,GO:0051716,GO:0051960,GO:0051962,GO:0051963,GO:0051965,GO:0060205,GO:0060215,GO:0060271,GO:0060284,GO:0060319,GO:0060429,GO:0060491,GO:0060998,GO:0060999,GO:0061001,GO:0061003,GO:0061024,GO:0061640,GO:0061825,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0070925,GO:0071236,GO:0071310,GO:0071345,GO:0071346,GO:0071407,GO:0071417,GO:0071437,GO:0071495,GO:0071840,GO:0071944,GO:0072553,GO:0090066,GO:0090130,GO:0090132,GO:0097305,GO:0097435,GO:0097458,GO:0097708,GO:0098657,GO:0098794,GO:0098813,GO:0098984,GO:0099080,GO:0099081,GO:0099172,GO:0099175,GO:0099503,GO:0099512,GO:0099513,GO:0099568,GO:0099572,GO:0101002,GO:0110053,GO:0120025,GO:0120031,GO:0120032,GO:0120035,GO:0120036,GO:0140013,GO:1900006,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902903,GO:1902905,GO:1903046,GO:1904396,GO:1904398,GO:1904813,GO:2000026	-	ko:K17260	ko04138,ko04530,map04138,map04530	-	-	-	ko00000,ko00001,ko04131,ko04147,ko04812	-	-	-	Actin
k59_268823_1	390235.PputW619_5212	1.63e-38	140.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1YX79@136845|Pseudomonas putida group	1236|Gammaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
k59_346909_1	566466.NOR53_2559	1.01e-23	100.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
k59_1169640_1	344747.PM8797T_17714	5.57e-14	76.6	COG4191@1|root,COG4191@2|Bacteria,2J037@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD,HisKA
k59_974276_1	1121405.dsmv_2733	5.87e-20	81.6	COG1550@1|root,COG1550@2|Bacteria,1N2H7@1224|Proteobacteria,42UCZ@68525|delta/epsilon subdivisions,2WR50@28221|Deltaproteobacteria,2MKM4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
k59_974276_2	1304885.AUEY01000003_gene545	1.93e-37	140.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2MIGT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k59_307686_1	1123288.SOV_4c07250	3.88e-17	87.0	COG0642@1|root,COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,4H3CB@909932|Negativicutes	909932|Negativicutes	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS_9
k59_346963_1	909663.KI867150_gene2418	1.14e-79	253.0	COG3848@1|root,COG3848@2|Bacteria,1MV5C@1224|Proteobacteria,43B08@68525|delta/epsilon subdivisions,2X6EC@28221|Deltaproteobacteria	1224|Proteobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
k59_503349_1	1382306.JNIM01000001_gene4159	1.06e-68	224.0	COG0114@1|root,COG0114@2|Bacteria,2GBNI@200795|Chloroflexi	200795|Chloroflexi	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
k59_307702_1	1003195.SCAT_5780	2.46e-07	54.3	COG3293@1|root,COG3293@2|Bacteria,2IHX5@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
k59_1052662_1	10685.PORTL_BPSP1	1.83e-86	275.0	4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses  no RNA stage	10239|Viruses	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1251099_2	525897.Dbac_1860	2.74e-30	116.0	COG1418@1|root,COG1418@2|Bacteria,1RGCM@1224|Proteobacteria,42RC5@68525|delta/epsilon subdivisions,2WNBA@28221|Deltaproteobacteria,2MBBU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	HD
k59_699124_1	1395516.PMO01_28165	5.49e-08	54.3	COG3568@1|root,COG3568@2|Bacteria,1RBWV@1224|Proteobacteria,1S296@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
k59_699124_2	754476.Q7A_2839	8.99e-63	207.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4601B@72273|Thiotrichales	72273|Thiotrichales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
k59_32537_1	686340.Metal_0539	1.02e-26	108.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,1RMIJ@1236|Gammaproteobacteria,1XEMZ@135618|Methylococcales	135618|Methylococcales	E	Periplasmic binding protein domain	-	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
k59_738071_1	933262.AXAM01000039_gene1149	7.83e-91	281.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,42MAA@68525|delta/epsilon subdivisions,2WJZC@28221|Deltaproteobacteria,2MHSM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
k59_32571_1	1423321.AS29_00610	1.43e-10	68.2	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,1ZC8B@1386|Bacillus	91061|Bacilli	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
k59_658887_1	1245471.PCA10_50020	4.53e-26	112.0	COG2132@1|root,COG2132@2|Bacteria,1N9H3@1224|Proteobacteria	1224|Proteobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22349	-	-	-	-	ko00000,ko01000	-	-	-	-
k59_292725_1	523791.Kkor_1955	2.22e-33	131.0	COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,1RZDP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
k59_1075260_1	644282.Deba_1015	6.25e-60	197.0	COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,42ND9@68525|delta/epsilon subdivisions,2WK5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_527694_1	90813.JQMT01000001_gene1669	2.06e-88	269.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria,463S8@72273|Thiotrichales	72273|Thiotrichales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
k59_527701_1	1127673.GLIP_3403	6.03e-28	117.0	COG2931@1|root,COG2931@2|Bacteria,1R0AV@1224|Proteobacteria,1T4G4@1236|Gammaproteobacteria,46C6H@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Reprolysin (M12B) family zinc metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_5
k59_958534_1	745014.OMB55_00017560	3.82e-78	241.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RZF4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG1410 Methionine synthase I cobalamin-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Pterin_bind
k59_527724_1	224911.27355218	6.94e-18	80.5	COG3118@1|root,COG3118@2|Bacteria,1QVD0@1224|Proteobacteria,2UAGJ@28211|Alphaproteobacteria,3JY8S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Hydrogenase-1 expression protein HyaE	hupG	-	-	ko:K03619	-	-	-	-	ko00000	-	-	-	HyaE
k59_527724_2	1485545.JQLW01000005_gene925	2.01e-12	68.6	COG1773@1|root,COG1773@2|Bacteria,1MV2U@1224|Proteobacteria	1224|Proteobacteria	C	PFAM HupH hydrogenase expression protein	hupH	-	-	ko:K03618	-	-	-	-	ko00000	-	-	-	HupH_C
k59_97308_1	216142.LT40_10935	2.1e-06	49.3	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,1RREX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit	bkdA1	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoDH_E1alpha_N
k59_97308_2	1112214.AHIS01000095_gene767	3.55e-24	102.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,2K0AY@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
k59_412886_2	395495.Lcho_4123	1.73e-52	186.0	COG3303@1|root,COG3303@2|Bacteria,1PEVM@1224|Proteobacteria,2VMWI@28216|Betaproteobacteria,1KN2G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
k59_1154130_2	444861.E3SPJ9_9CAUD	1.83e-06	47.0	4QEUF@10239|Viruses,4QXBZ@35237|dsDNA viruses  no RNA stage,4QS1E@28883|Caudovirales	28883|Caudovirales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1235742_1	335543.Sfum_1580	5.03e-37	127.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,42R43@68525|delta/epsilon subdivisions,2WPH1@28221|Deltaproteobacteria,2MQGH@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
k59_1235742_2	880072.Desac_1429	8.15e-61	191.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria,2MRHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
k59_412891_1	933262.AXAM01000013_gene1324	4e-18	87.8	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2MIGT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
k59_412900_1	1479237.JMLY01000001_gene2462	2.3e-41	145.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,466TM@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
k59_448947_1	550540.Fbal_3032	2.06e-33	119.0	COG3450@1|root,COG3450@2|Bacteria,1N0F7@1224|Proteobacteria,1S92W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	transcriptional regulator	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
k59_1075317_1	936136.ARRT01000007_gene1276	1.52e-32	138.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TUKX@28211|Alphaproteobacteria,4BAF2@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_723584_1	247639.MGP2080_02595	1.88e-170	488.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,1RYNM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EQ	peptidase S58 DmpA	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
k59_723584_2	983920.Y88_3702	7.09e-14	70.5	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2TQPM@28211|Alphaproteobacteria,2K017@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
k59_56639_1	1121405.dsmv_0470	2.05e-37	137.0	COG1680@1|root,COG1680@2|Bacteria,1QUYZ@1224|Proteobacteria,42PUC@68525|delta/epsilon subdivisions,2WK0V@28221|Deltaproteobacteria,2MIWD@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_135284_1	977880.RALTA_A1940	2.69e-52	166.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,1K7US@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
k59_800885_1	9606.ENSP00000241052	7.37e-148	428.0	COG0753@1|root,KOG0047@2759|Eukaryota,38BMC@33154|Opisthokonta,3BFAV@33208|Metazoa,3CSMT@33213|Bilateria,48809@7711|Chordata,48VHW@7742|Vertebrata,3JAIA@40674|Mammalia,35NC8@314146|Euarchontoglires,4M7PK@9443|Primates,4N5Y2@9604|Hominidae	33208|Metazoa	P	catalase activity	CAT	GO:0000166,GO:0000302,GO:0000323,GO:0001101,GO:0001655,GO:0001657,GO:0001666,GO:0001775,GO:0001822,GO:0001823,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0003007,GO:0003674,GO:0003824,GO:0004046,GO:0004096,GO:0004601,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005764,GO:0005773,GO:0005777,GO:0005778,GO:0005782,GO:0005783,GO:0005794,GO:0005829,GO:0005886,GO:0006066,GO:0006091,GO:0006355,GO:0006605,GO:0006625,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006807,GO:0006810,GO:0006886,GO:0006887,GO:0006950,GO:0006955,GO:0006979,GO:0006996,GO:0007031,GO:0007154,GO:0007267,GO:0007275,GO:0007507,GO:0007568,GO:0007584,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008340,GO:0009056,GO:0009060,GO:0009314,GO:0009411,GO:0009416,GO:0009605,GO:0009628,GO:0009636,GO:0009642,GO:0009650,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010193,GO:0010243,GO:0010259,GO:0010288,GO:0010468,GO:0010556,GO:0010646,GO:0010647,GO:0010941,GO:0012505,GO:0014066,GO:0014068,GO:0014070,GO:0014823,GO:0014854,GO:0015031,GO:0015833,GO:0015980,GO:0016020,GO:0016043,GO:0016125,GO:0016192,GO:0016209,GO:0016491,GO:0016627,GO:0016628,GO:0016684,GO:0016787,GO:0016810,GO:0016811,GO:0016999,GO:0017001,GO:0017144,GO:0019166,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0020027,GO:0020037,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030141,GO:0031090,GO:0031323,GO:0031326,GO:0031410,GO:0031667,GO:0031903,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031982,GO:0031983,GO:0032088,GO:0032355,GO:0032501,GO:0032502,GO:0032868,GO:0032940,GO:0033036,GO:0033189,GO:0033197,GO:0033273,GO:0033365,GO:0033554,GO:0033591,GO:0033993,GO:0034284,GO:0034599,GO:0034613,GO:0034774,GO:0034976,GO:0035206,GO:0035295,GO:0036094,GO:0036230,GO:0036293,GO:0036296,GO:0036335,GO:0038001,GO:0042119,GO:0042127,GO:0042221,GO:0042493,GO:0042542,GO:0042579,GO:0042592,GO:0042737,GO:0042743,GO:0042744,GO:0042802,GO:0042803,GO:0042886,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043433,GO:0043434,GO:0043574,GO:0043933,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044260,GO:0044281,GO:0044421,GO:0044422,GO:0044424,GO:0044429,GO:0044433,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045184,GO:0045321,GO:0045333,GO:0045471,GO:0046486,GO:0046677,GO:0046686,GO:0046688,GO:0046903,GO:0046906,GO:0046907,GO:0046983,GO:0048037,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0048872,GO:0050661,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051090,GO:0051091,GO:0051092,GO:0051171,GO:0051179,GO:0051186,GO:0051187,GO:0051234,GO:0051239,GO:0051252,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051641,GO:0051649,GO:0051716,GO:0055093,GO:0055114,GO:0060205,GO:0060255,GO:0060429,GO:0060548,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070482,GO:0070542,GO:0070727,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0072001,GO:0072073,GO:0072163,GO:0072164,GO:0072359,GO:0072593,GO:0072594,GO:0072662,GO:0072663,GO:0080090,GO:0080184,GO:0097159,GO:0097237,GO:0097305,GO:0097708,GO:0098588,GO:0098754,GO:0098805,GO:0098869,GO:0099503,GO:0101002,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901615,GO:1901652,GO:1901698,GO:1901700,GO:1902531,GO:1902533,GO:1902652,GO:1903506,GO:1904813,GO:1990748,GO:2000112,GO:2001141	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
k59_214416_1	1123401.JHYQ01000003_gene2109	2.07e-38	152.0	28HYC@1|root,2Z83T@2|Bacteria,1QEBM@1224|Proteobacteria,1RRCK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_566581_1	686340.Metal_3316	1.1e-134	401.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1XDNZ@135618|Methylococcales	135618|Methylococcales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
k59_684250_1	717785.HYPMC_0374	2.89e-58	192.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,3N6GD@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
k59_687001_1	933262.AXAM01000057_gene1541	9.91e-107	313.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,42N4U@68525|delta/epsilon subdivisions,2WJR7@28221|Deltaproteobacteria,2MHSN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
k59_177790_1	519989.ECTPHS_01334	3e-37	140.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1WX4I@135613|Chromatiales	135613|Chromatiales	D	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
k59_764893_1	1121405.dsmv_3580	2.19e-40	134.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2WR6G@28221|Deltaproteobacteria,2MKWR@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
k59_764893_2	933262.AXAM01000052_gene2000	8.84e-52	165.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,42RHR@68525|delta/epsilon subdivisions,2WNEK@28221|Deltaproteobacteria,2MJSK@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
k59_1156852_1	1121918.ARWE01000001_gene188	2.96e-43	145.0	COG4852@1|root,COG4852@2|Bacteria,1MZHP@1224|Proteobacteria,42TD7@68525|delta/epsilon subdivisions,2WPIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
k59_334079_1	177439.DP2116	1.71e-74	245.0	COG0531@1|root,COG0531@2|Bacteria,1PVV2@1224|Proteobacteria,433CQ@68525|delta/epsilon subdivisions,2WXZF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
k59_882749_1	309807.SRU_0558	5.51e-10	62.0	COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,1FITH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_882749_2	1144275.COCOR_06096	4.62e-28	113.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2YTX5@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_687032_1	269799.Gmet_2822	5.44e-58	199.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria,43UGA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
k59_569241_1	1121396.KB893046_gene3309	4.6e-15	74.3	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2WJ81@28221|Deltaproteobacteria,2MI27@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
k59_218078_1	1396141.BATP01000059_gene2584	4.39e-114	337.0	COG2321@1|root,COG2321@2|Bacteria,46XBD@74201|Verrucomicrobia,2IVAT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zn_peptidase
k59_218078_2	880073.Calab_1849	1.32e-12	68.2	COG2094@1|root,COG2094@2|Bacteria,2NPMI@2323|unclassified Bacteria	2|Bacteria	L	Belongs to the DNA glycosylase MPG family	mpg	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
k59_843488_1	1127673.GLIP_3816	1.18e-73	251.0	28HKI@1|root,2Z7VC@2|Bacteria,1MW0I@1224|Proteobacteria,1RQ5H@1236|Gammaproteobacteria,469C8@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_100123_1	9606.ENSP00000362463	1.35e-105	305.0	COG0346@1|root,KOG2944@2759|Eukaryota,38CS6@33154|Opisthokonta,3BARY@33208|Metazoa,3D1NZ@33213|Bilateria,48020@7711|Chordata,492MZ@7742|Vertebrata,3JCKZ@40674|Mammalia,35HA2@314146|Euarchontoglires,4M6H6@9443|Primates,4MZIJ@9604|Hominidae	33208|Metazoa	G	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	GLO1	GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0003674,GO:0003824,GO:0004462,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006089,GO:0006090,GO:0006355,GO:0006357,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009438,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010941,GO:0016020,GO:0016829,GO:0016846,GO:0019219,GO:0019222,GO:0019243,GO:0019752,GO:0030097,GO:0030099,GO:0030154,GO:0030316,GO:0031323,GO:0031326,GO:0032501,GO:0032502,GO:0032787,GO:0034641,GO:0042180,GO:0042182,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046872,GO:0046914,GO:0048513,GO:0048519,GO:0048523,GO:0048534,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051186,GO:0051252,GO:0051596,GO:0060255,GO:0060548,GO:0061727,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901575,GO:1901615,GO:1903506,GO:2000112,GO:2001141	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
k59_764933_1	401053.AciPR4_2233	5.72e-07	52.4	COG5285@1|root,COG5285@2|Bacteria,3Y7QH@57723|Acidobacteria,2JMPG@204432|Acidobacteriia	204432|Acidobacteriia	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
k59_764933_2	1121861.KB899926_gene2601	1.56e-24	107.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2JVYE@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
k59_1004920_1	1121937.AUHJ01000009_gene1539	1.61e-57	194.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,1RMMN@1236|Gammaproteobacteria,464MI@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	lthA	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
k59_59295_1	1265505.ATUG01000001_gene4336	8.8e-104	310.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,42N7R@68525|delta/epsilon subdivisions,2WJBI@28221|Deltaproteobacteria,2MIB1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
k59_491125_1	522306.CAP2UW1_2212	6.15e-07	53.1	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VMUZ@28216|Betaproteobacteria,1KQTS@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_1077942_1	1004785.AMBLS11_05435	2.8e-98	314.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,465ZZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
k59_1004946_1	391593.RCCS2_10415	3.77e-90	273.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2P2F2@2433|Roseobacter	28211|Alphaproteobacteria	P	COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_1239247_2	566466.NOR53_6	2.99e-17	82.0	COG0457@1|root,COG0457@2|Bacteria,1RC07@1224|Proteobacteria,1S36N@1236|Gammaproteobacteria,1J9HJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
k59_137940_1	1384056.N787_01370	1.3e-51	184.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X3PQ@135614|Xanthomonadales	135614|Xanthomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
k59_218182_1	879212.DespoDRAFT_02905	6.95e-48	164.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42MAQ@68525|delta/epsilon subdivisions,2WKK0@28221|Deltaproteobacteria,2MINE@213118|Desulfobacterales	28221|Deltaproteobacteria	E	transport system permease	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
k59_416725_2	1158165.KB898874_gene1821	0.00061	41.6	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,1RRRC@1236|Gammaproteobacteria,1X1AR@135613|Chromatiales	135613|Chromatiales	M	OmpW family	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
k59_137973_1	1240350.AMZE01000012_gene3585	2.95e-69	221.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1YV93@136845|Pseudomonas putida group	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3734,iSBO_1134.SBO_4018	URO-D
k59_256391_1	106370.Francci3_3776	2.98e-68	221.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4EREY@85013|Frankiales	201174|Actinobacteria	I	PFAM Alpha beta hydrolase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
k59_451741_1	616991.JPOO01000003_gene1766	1.07e-73	239.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1HY2W@117743|Flavobacteriia,23G90@178469|Arenibacter	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
k59_295803_1	575540.Isop_2761	2.55e-47	172.0	COG2373@1|root,COG2373@2|Bacteria,2IWRT@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
k59_961544_1	118005.AWNK01000001_gene1805	3.51e-14	68.9	COG3807@1|root,COG3807@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	yrvJ	-	3.2.1.96,3.4.17.14,3.5.1.28	ko:K01227,ko:K01447,ko:K01448,ko:K06385,ko:K07260,ko:K11060,ko:K11062	ko00511,ko00550,ko01100,ko01502,ko01503,ko02020,map00511,map00550,map01100,map01502,map01503,map02020	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02042,ko03036	-	-	-	Amidase_3,Glucosaminidase,NLPC_P60,SH3_3,SH3_4
k59_961544_2	96561.Dole_2854	1.39e-57	190.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,42M1U@68525|delta/epsilon subdivisions,2WKK5@28221|Deltaproteobacteria,2MINI@213118|Desulfobacterales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
k59_218236_1	234267.Acid_2264	6.32e-38	142.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
k59_961549_1	1278307.KB906976_gene1564	3.32e-72	240.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RNWM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
k59_921204_1	926550.CLDAP_38230	1.39e-53	180.0	COG1171@1|root,COG1171@2|Bacteria,2G69F@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
k59_687181_1	481448.Minf_1007	7.55e-11	64.3	COG0160@1|root,COG0160@2|Bacteria,46TQB@74201|Verrucomicrobia,37FW4@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-III	gabT	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
k59_961559_1	1304885.AUEY01000073_gene1461	1.05e-18	88.2	COG1652@1|root,COG2885@1|root,COG1652@2|Bacteria,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,2MJUT@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
k59_334265_1	546262.NEICINOT_04282	9.93e-28	113.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,2KPME@206351|Neisseriales	206351|Neisseriales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
k59_218275_1	1049564.TevJSym_bc00380	1.77e-130	381.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1JBG6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cysteine-rich domain	dgcB	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
k59_416789_1	102129.Lepto7375DRAFT_0381	8.06e-61	199.0	COG3367@1|root,COG3367@2|Bacteria,1GA7A@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG3367 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_803570_1	95619.PM1_0203270	2.04e-112	340.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
k59_1118148_1	1170562.Cal6303_5468	4.4e-20	92.8	COG0642@1|root,COG0745@1|root,COG2203@1|root,COG2905@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2905@2|Bacteria,1G09B@1117|Cyanobacteria,1HKCU@1161|Nostocales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
k59_1118148_2	411479.BACUNI_03262	6.13e-09	57.8	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,4NDXU@976|Bacteroidetes,2FM06@200643|Bacteroidia,4APRB@815|Bacteroidaceae	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
k59_1157061_1	1267005.KB911257_gene700	2.85e-73	230.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,2TS2U@28211|Alphaproteobacteria,3N6QK@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	NU	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
k59_59417_1	439235.Dalk_3619	1.07e-14	73.9	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42PRI@68525|delta/epsilon subdivisions,2X5GA@28221|Deltaproteobacteria,2MHVA@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
k59_1239391_1	439235.Dalk_2669	4.08e-71	243.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
k59_1118154_1	1177154.Y5S_00143	5.33e-08	58.9	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1R9DM@1224|Proteobacteria,1S0EG@1236|Gammaproteobacteria,1XR5N@135619|Oceanospirillales	135619|Oceanospirillales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Response_reg
k59_20562_1	1408428.JNJP01000019_gene1638	2.59e-31	121.0	COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,42NJB@68525|delta/epsilon subdivisions,2WM62@28221|Deltaproteobacteria,2M967@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2333
k59_904085_1	617140.AJZE01000014_gene1128	1.5e-78	258.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1XSUS@135623|Vibrionales	135623|Vibrionales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
k59_3231_1	318167.Sfri_0277	4.41e-25	105.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,2QAA7@267890|Shewanellaceae	1236|Gammaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
k59_512622_1	1187851.A33M_0769	1.48e-10	65.1	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2TTGT@28211|Alphaproteobacteria,3FEEI@34008|Rhodovulum	28211|Alphaproteobacteria	H	Aldolase/RraA	ligK	-	4.1.3.17	ko:K02553,ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000,ko03019	-	-	-	RraA-like
k59_865024_1	883126.HMPREF9710_02547	1.97e-20	92.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VICM@28216|Betaproteobacteria,474WD@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
k59_395209_1	1121405.dsmv_3176	1.96e-70	233.0	COG4191@1|root,COG4191@2|Bacteria,1R7KQ@1224|Proteobacteria,42PAP@68525|delta/epsilon subdivisions,2WITB@28221|Deltaproteobacteria,2MHP3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
k59_1139100_1	879212.DespoDRAFT_02168	2.21e-11	61.6	COG2111@1|root,COG2111@2|Bacteria,1REGG@1224|Proteobacteria,42UA1@68525|delta/epsilon subdivisions,2WQHA@28221|Deltaproteobacteria,2MKH4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Domain related to MnhB subunit of Na+/H+ antiporter	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
k59_1139100_2	497321.C664_19306	1.16e-18	87.8	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,2VK56@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit	-	-	-	ko:K05565	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
k59_433921_1	177437.HRM2_49200	1.22e-92	286.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42N74@68525|delta/epsilon subdivisions,2WKUN@28221|Deltaproteobacteria,2MI16@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K15584	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
k59_5804_1	9606.ENSP00000246957	1.79e-131	392.0	COG0326@1|root,KOG0019@2759|Eukaryota,39R0C@33154|Opisthokonta,3BAN6@33208|Metazoa,3D0I8@33213|Bilateria,489TT@7711|Chordata,48URS@7742|Vertebrata,3J7RI@40674|Mammalia,35BYI@314146|Euarchontoglires,4MCX4@9443|Primates,4MUG8@9604|Hominidae	33208|Metazoa	O	Hsp90 protein	TRAP1	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005102,GO:0005126,GO:0005164,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005758,GO:0005759,GO:0006417,GO:0006457,GO:0006950,GO:0006979,GO:0006986,GO:0008150,GO:0009266,GO:0009386,GO:0009408,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010608,GO:0010646,GO:0010648,GO:0010941,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019866,GO:0019899,GO:0019900,GO:0019901,GO:0023051,GO:0023057,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031966,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031981,GO:0031982,GO:0032268,GO:0032813,GO:0033554,GO:0034248,GO:0034514,GO:0034605,GO:0034620,GO:0035966,GO:0035967,GO:0042221,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0043231,GO:0043233,GO:0043457,GO:0043467,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051171,GO:0051246,GO:0051716,GO:0060255,GO:0060548,GO:0061077,GO:0065007,GO:0070013,GO:0070062,GO:0070887,GO:0071310,GO:0080090,GO:0080134,GO:0080135,GO:0097159,GO:1900407,GO:1900408,GO:1901031,GO:1901032,GO:1901298,GO:1901299,GO:1901363,GO:1901856,GO:1902175,GO:1902176,GO:1902531,GO:1902532,GO:1902882,GO:1902883,GO:1902884,GO:1903201,GO:1903202,GO:1903205,GO:1903206,GO:1903426,GO:1903427,GO:1903561,GO:1903750,GO:1903751,GO:2000112,GO:2000377,GO:2000378,GO:2001023,GO:2001024,GO:2001038,GO:2001039,GO:2001233,GO:2001234,GO:2001242,GO:2001243	-	ko:K09488	-	-	-	-	ko00000,ko03110	-	-	-	HATPase_c_3,HSP90
k59_358540_1	519989.ECTPHS_02516	1.91e-06	50.1	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1WWAT@135613|Chromatiales	135613|Chromatiales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
k59_358540_2	519989.ECTPHS_09243	8.79e-28	107.0	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,1WYH2@135613|Chromatiales	135613|Chromatiales	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
k59_1024656_1	1208919.CDSE_0864	2.87e-08	65.5	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria,1KPSR@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
k59_554136_1	477974.Daud_0093	1.73e-11	64.7	COG0247@1|root,COG0247@2|Bacteria,1UZQ0@1239|Firmicutes,24E5H@186801|Clostridia,2672H@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17
k59_1181429_1	926692.AZYG01000085_gene856	3.43e-79	252.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,249HN@186801|Clostridia,3WA8E@53433|Halanaerobiales	186801|Clostridia	L	Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_1181429_2	522373.Smlt0027	9.96e-22	88.6	COG2963@1|root,COG2963@2|Bacteria,1N28U@1224|Proteobacteria,1S9BK@1236|Gammaproteobacteria,1XAPX@135614|Xanthomonadales	135614|Xanthomonadales	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_632688_2	1150469.RSPPHO_00624	3.02e-63	211.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,2JPZX@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
k59_44678_1	1122132.AQYH01000006_gene3672	2.5e-50	173.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TUMJ@28211|Alphaproteobacteria,4BDSM@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
k59_1220356_1	102125.Xen7305DRAFT_00054060	3.34e-55	186.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,3VJBK@52604|Pleurocapsales	1117|Cyanobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
k59_1141828_1	706587.Desti_2952	1.05e-111	342.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2MR0I@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8	ko:K01782,ko:K01825	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_867450_1	1123373.ATXI01000010_gene1044	3.33e-45	156.0	COG0082@1|root,COG0082@2|Bacteria,2GGRE@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
k59_1024701_1	203122.Sde_3568	5.26e-44	150.0	2B4XH@1|root,31XQC@2|Bacteria,1RHJF@1224|Proteobacteria,1S3S1@1236|Gammaproteobacteria,467JQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_1024701_2	1123053.AUDG01000012_gene1677	1.61e-08	53.5	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1X2BZ@135613|Chromatiales	135613|Chromatiales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
k59_945937_1	398527.Bphyt_2615	4.75e-31	120.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,1K39W@119060|Burkholderiaceae	28216|Betaproteobacteria	E	glutamine synthetase	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
k59_945937_2	1282876.BAOK01000001_gene2274	1.1e-34	121.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,4BQ9M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the P(II) protein family	glnB	GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
k59_515334_1	748658.KB907314_gene174	1.68e-14	77.4	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1WWK8@135613|Chromatiales	135613|Chromatiales	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
k59_750013_1	1094980.Mpsy_0389	2.97e-43	152.0	COG0053@1|root,arCOG01474@2157|Archaea,2XU96@28890|Euryarchaeota,2N9HJ@224756|Methanomicrobia	224756|Methanomicrobia	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
k59_358594_1	1121405.dsmv_1738	3.48e-82	248.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2WNA5@28221|Deltaproteobacteria,2MK12@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
k59_1220379_1	335543.Sfum_1698	4.97e-110	348.0	COG1205@1|root,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria,2MQS2@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	yprA	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,RNase_H_2
k59_593422_1	1123053.AUDG01000009_gene3771	1.8e-50	177.0	COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,1RMJY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Tryptophan halogenase	prnA	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
k59_5890_1	1245471.PCA10_29450	5.68e-111	331.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,1RZC3@1236|Gammaproteobacteria,1YJT3@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
k59_828409_1	296591.Bpro_5322	5.93e-36	131.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2VHN6@28216|Betaproteobacteria,4ACDX@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
k59_397869_1	933262.AXAM01000016_gene167	2.34e-76	244.0	COG0664@1|root,COG0664@2|Bacteria,1RCF4@1224|Proteobacteria,43BRQ@68525|delta/epsilon subdivisions,2X72K@28221|Deltaproteobacteria,2MJHW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,cNMP_binding
k59_710636_1	1121405.dsmv_3773	2.82e-84	273.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,42NY6@68525|delta/epsilon subdivisions,2WJSE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
k59_279910_1	195250.CM001776_gene2304	3.22e-14	75.5	COG0216@1|root,COG0216@2|Bacteria,1FZY4@1117|Cyanobacteria,1GYAU@1129|Synechococcus	1117|Cyanobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
k59_5903_1	335543.Sfum_0445	9.77e-84	257.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WPA2@28221|Deltaproteobacteria,2MQIC@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Cytochrome b/b6/petB	cbcW	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B,Cytochrome_CBB3
k59_515351_1	744985.HIMB59_00005800	1.74e-136	404.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,4BP9G@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	MA20_29420	-	6.2.1.48	ko:K00666,ko:K02182	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
k59_436552_1	1122933.JNIY01000004_gene2520	1.12e-53	179.0	COG0385@1|root,COG0385@2|Bacteria,2GNES@201174|Actinobacteria	201174|Actinobacteria	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
k59_201426_1	1121286.AUMT01000022_gene1698	7.22e-49	164.0	COG2801@1|root,COG2801@2|Bacteria,4NF3Q@976|Bacteroidetes,1HZT4@117743|Flavobacteriia,3ZRFJ@59732|Chryseobacterium	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
k59_436564_1	926550.CLDAP_08980	2.47e-67	216.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
k59_1102947_2	1278309.KB907104_gene901	8.58e-95	286.0	COG1638@1|root,COG1638@2|Bacteria,1QJDA@1224|Proteobacteria,1RR0A@1236|Gammaproteobacteria,1XIX1@135619|Oceanospirillales	135619|Oceanospirillales	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_5953_1	1267534.KB906754_gene3585	5.62e-06	55.1	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
k59_671800_1	1279017.AQYJ01000026_gene58	1.05e-68	234.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1R5G4@1224|Proteobacteria,1SEWA@1236|Gammaproteobacteria,469S7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
k59_436601_1	643562.Daes_2867	9.01e-49	167.0	COG0457@1|root,COG0457@2|Bacteria,1MYZU@1224|Proteobacteria,42SNQ@68525|delta/epsilon subdivisions,2WPHI@28221|Deltaproteobacteria,2M842@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
k59_397922_1	189753.AXAS01000075_gene6010	2.91e-89	278.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2TRXG@28211|Alphaproteobacteria,3JVHX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
k59_1024786_1	246200.SPO0413	4.38e-71	227.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,4NBKU@97050|Ruegeria	28211|Alphaproteobacteria	E	Methionine gamma-lyase	mdeA	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
k59_1063730_1	392500.Swoo_4366	8.81e-57	197.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 3 family	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
k59_632861_2	177439.DP0743	8.63e-10	60.8	COG0589@1|root,COG0589@2|Bacteria,1N5PT@1224|Proteobacteria,42UH3@68525|delta/epsilon subdivisions,2WR0A@28221|Deltaproteobacteria,2MKTU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
k59_123540_1	1121405.dsmv_1244	6.7e-94	283.0	COG1082@1|root,COG1082@2|Bacteria,1N8KJ@1224|Proteobacteria,42R37@68525|delta/epsilon subdivisions,2WMX6@28221|Deltaproteobacteria,2MJQB@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
k59_44804_1	1121939.L861_18550	5.04e-87	259.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1XIJW@135619|Oceanospirillales	135619|Oceanospirillales	H	catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
k59_84764_1	83406.HDN1F_08600	1.45e-129	383.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1J55X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
k59_201511_1	349124.Hhal_2093	5.61e-11	63.2	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1WWI1@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
k59_201511_2	1121035.AUCH01000009_gene911	6.41e-16	80.1	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,2KUH4@206389|Rhodocyclales	206389|Rhodocyclales	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
k59_710753_1	706587.Desti_4287	1.23e-32	122.0	COG1413@1|root,COG1413@2|Bacteria,1R6G4@1224|Proteobacteria,42T2X@68525|delta/epsilon subdivisions,2WPNC@28221|Deltaproteobacteria,2MRRI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_EZ
k59_985716_1	686578.AFFX01000006_gene3220	6.3e-46	164.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	clsC	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
k59_319069_1	526227.Mesil_0899	7.72e-54	174.0	COG2606@1|root,COG2606@2|Bacteria,1WJSU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YbaK prolyl-tRNA synthetase associated	ebsC	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
k59_554277_1	1487923.DP73_17590	1.7e-61	208.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,2606T@186807|Peptococcaceae	186801|Clostridia	P	pyridine nucleotide-disulphide oxidoreductase dimerisation	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
k59_985720_1	335543.Sfum_1147	2.58e-96	295.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,42M60@68525|delta/epsilon subdivisions,2WITJ@28221|Deltaproteobacteria,2MQT6@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	dsrK	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
k59_554287_1	10116.ENSRNOP00000067716	1.72e-138	432.0	KOG1075@1|root,KOG1075@2759|Eukaryota,39RKB@33154|Opisthokonta,3BK61@33208|Metazoa,3E43G@33213|Bilateria,48JXY@7711|Chordata,49GK2@7742|Vertebrata,3JJ5B@40674|Mammalia,35U9R@314146|Euarchontoglires	33208|Metazoa	S	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1725,Exo_endo_phos,Exo_endo_phos_2,RVT_1
k59_397975_1	667014.Thein_0015	1.61e-50	171.0	COG0451@1|root,COG0451@2|Bacteria,2GIE7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	NmrA-like family	-	-	5.1.3.7	ko:K02473	ko00520,ko01100,map00520,map01100	-	R00418	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
k59_6067_2	706587.Desti_2042	5.41e-76	243.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2WK1D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
k59_475986_2	1521187.JPIM01000047_gene124	1.99e-13	73.6	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,375DF@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
k59_906852_1	1255043.TVNIR_3846	1.29e-95	295.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1WVY6@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
k59_710803_2	1187848.AJYQ01000003_gene410	2.97e-86	270.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1TFGA@1236|Gammaproteobacteria,1XXNF@135623|Vibrionales	135623|Vibrionales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
k59_358766_1	247639.MGP2080_13889	5.7e-45	162.0	COG2207@1|root,COG2207@2|Bacteria,1RH01@1224|Proteobacteria,1S57M@1236|Gammaproteobacteria,1JAT7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	AraC-type DNA-binding domain-containing proteins	oruR	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
k59_436701_1	1121875.KB907546_gene2199	2.63e-70	228.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1I2RR@117743|Flavobacteriia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
k59_201583_1	997346.HMPREF9374_0941	5.19e-43	154.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,27AU2@186824|Thermoactinomycetaceae	91061|Bacilli	H	DNA / pantothenate metabolism flavoprotein	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
k59_1220567_1	1449048.JQKU01000009_gene836	7.95e-08	56.6	COG1595@1|root,COG1595@2|Bacteria,2IHYZ@201174|Actinobacteria,2399Y@1762|Mycobacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
k59_554327_1	396588.Tgr7_2195	3.61e-56	181.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,1RRYZ@1236|Gammaproteobacteria,1WVZM@135613|Chromatiales	135613|Chromatiales	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_7
k59_554327_2	413404.Rmag_0859	1.64e-81	254.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,1SMKH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
k59_789595_1	998674.ATTE01000001_gene2068	9.21e-69	221.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,4606I@72273|Thiotrichales	72273|Thiotrichales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
k59_1063857_1	666686.B1NLA3E_09690	3.87e-18	84.3	arCOG09454@1|root,30G4A@2|Bacteria,1V448@1239|Firmicutes,4HHA0@91061|Bacilli,1ZGUC@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_554361_1	1064537.AGSO01000015_gene1028	7.87e-21	98.6	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4FCHA@85020|Dermabacteraceae	201174|Actinobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
k59_946158_2	314275.MADE_1013985	4.27e-69	214.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,466EY@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
k59_201630_1	1280953.HOC_18129	1.51e-55	185.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2TR4R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	MA20_01040	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
k59_1142088_1	318161.Sden_3429	2.38e-71	231.0	COG0845@1|root,COG0845@2|Bacteria,1MV1T@1224|Proteobacteria,1RQTS@1236|Gammaproteobacteria,2QBAZ@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
k59_655092_1	1158756.AQXQ01000012_gene1577	3.18e-110	340.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales	135613|Chromatiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
k59_695234_1	1121937.AUHJ01000008_gene2117	1.65e-105	314.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,46527@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
k59_734165_1	998674.ATTE01000001_gene1368	2.67e-53	181.0	COG1063@1|root,COG1063@2|Bacteria,1MWX0@1224|Proteobacteria,1RZYQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
k59_1013727_1	519989.ECTPHS_01879	2.64e-57	192.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1WW6B@135613|Chromatiales	135613|Chromatiales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
k59_1013727_2	1205680.CAKO01000030_gene4765	3.87e-05	46.6	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,2JPRS@204441|Rhodospirillales	204441|Rhodospirillales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
k59_542170_1	1265503.KB905166_gene652	6.38e-23	102.0	COG5616@1|root,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,1S0KQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_851577_1	1192034.CAP_6891	3.11e-17	81.3	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2YVNG@29|Myxococcales	28221|Deltaproteobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
k59_577890_1	189426.PODO_27005	1.84e-09	61.6	COG0600@1|root,COG0600@2|Bacteria,1TQ26@1239|Firmicutes,4IQR9@91061|Bacilli,2750N@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter permease	-	-	-	ko:K15554	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.2	-	-	BPD_transp_1
k59_577890_2	1532557.JL37_22875	3.39e-14	71.2	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	MA20_38155	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Polyketide_cyc2,TetR_N
k59_184985_1	1410634.JHVD01000010_gene2367	2.88e-05	52.0	COG0007@1|root,COG0007@2|Bacteria,2GK3B@201174|Actinobacteria,4DN4H@85009|Propionibacteriales	201174|Actinobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,NAD_binding_7,TP_methylase
k59_1165607_1	247634.GPB2148_3282	6.12e-49	176.0	COG0834@1|root,COG1301@1|root,COG0834@2|Bacteria,COG1301@2|Bacteria,1P22C@1224|Proteobacteria,1RSGY@1236|Gammaproteobacteria,1J8Z6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3,SDF
k59_617471_1	1381123.AYOD01000035_gene3613	2.45e-28	113.0	COG2890@1|root,COG2890@2|Bacteria,1RHJW@1224|Proteobacteria,2U68I@28211|Alphaproteobacteria,43PCM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
k59_970340_1	9541.XP_005552119.1	2.55e-158	466.0	COG5147@1|root,KOG0048@2759|Eukaryota,38EUR@33154|Opisthokonta,3BAYQ@33208|Metazoa,3CXMK@33213|Bilateria,482Q6@7711|Chordata,495RC@7742|Vertebrata,3JD7J@40674|Mammalia,35B77@314146|Euarchontoglires,4MAH1@9443|Primates,365H5@314294|Cercopithecoidea	33208|Metazoa	K	LMSTEN motif	MYB	GO:0000003,GO:0000082,GO:0000086,GO:0000117,GO:0000122,GO:0000226,GO:0000228,GO:0000278,GO:0000281,GO:0000785,GO:0000790,GO:0000791,GO:0000910,GO:0000976,GO:0000977,GO:0000978,GO:0000981,GO:0000982,GO:0000987,GO:0000988,GO:0000989,GO:0001012,GO:0001067,GO:0001076,GO:0001077,GO:0001134,GO:0001135,GO:0001228,GO:0001701,GO:0001775,GO:0002064,GO:0002065,GO:0002066,GO:0002376,GO:0002520,GO:0002521,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0002697,GO:0002699,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005700,GO:0005719,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006277,GO:0006323,GO:0006325,GO:0006338,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006725,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006996,GO:0007010,GO:0007017,GO:0007030,GO:0007049,GO:0007051,GO:0007088,GO:0007098,GO:0007099,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007304,GO:0007306,GO:0007307,GO:0007346,GO:0008150,GO:0008152,GO:0008283,GO:0008284,GO:0008361,GO:0009058,GO:0009059,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010256,GO:0010389,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0010927,GO:0010971,GO:0016043,GO:0016070,GO:0016363,GO:0017145,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019904,GO:0019953,GO:0022402,GO:0022407,GO:0022409,GO:0022412,GO:0022414,GO:0022607,GO:0030001,GO:0030097,GO:0030098,GO:0030099,GO:0030154,GO:0030155,GO:0030183,GO:0030261,GO:0030703,GO:0030707,GO:0030855,GO:0031023,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031399,GO:0031401,GO:0031523,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032774,GO:0032989,GO:0032991,GO:0033043,GO:0033044,GO:0034097,GO:0034399,GO:0034641,GO:0034645,GO:0034654,GO:0035295,GO:0042113,GO:0042127,GO:0042221,GO:0042592,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043370,GO:0043372,GO:0043565,GO:0044085,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044839,GO:0044843,GO:0045321,GO:0045580,GO:0045582,GO:0045595,GO:0045597,GO:0045619,GO:0045621,GO:0045622,GO:0045624,GO:0045785,GO:0045787,GO:0045792,GO:0045892,GO:0045893,GO:0045931,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046634,GO:0046635,GO:0046637,GO:0046638,GO:0046649,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048536,GO:0048538,GO:0048565,GO:0048566,GO:0048568,GO:0048583,GO:0048584,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0048872,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051249,GO:0051251,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051298,GO:0051301,GO:0051569,GO:0051570,GO:0051571,GO:0051574,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0055123,GO:0060255,GO:0060429,GO:0061640,GO:0065007,GO:0065008,GO:0070013,GO:0070741,GO:0070838,GO:0070887,GO:0070925,GO:0071103,GO:0071310,GO:0071345,GO:0071354,GO:0071704,GO:0071840,GO:0071897,GO:0071987,GO:0072511,GO:0080090,GO:0090066,GO:0090068,GO:0090282,GO:0090304,GO:0097159,GO:0097659,GO:0098534,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901532,GO:1901576,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902036,GO:1902105,GO:1902107,GO:1902275,GO:1902679,GO:1902680,GO:1902749,GO:1902751,GO:1903037,GO:1903039,GO:1903047,GO:1903506,GO:1903507,GO:1903508,GO:1903706,GO:1903708,GO:1905269,GO:1990823,GO:1990830,GO:1990837,GO:2000026,GO:2000112,GO:2000113,GO:2000514,GO:2000516,GO:2000736,GO:2001141,GO:2001252	-	ko:K09420,ko:K09421,ko:K21769	ko04151,ko04218,ko05166,map04151,map04218,map05166	-	-	-	ko00000,ko00001,ko03000	-	-	-	Cmyb_C,LMSTEN,Myb_DNA-binding
k59_343049_1	1117647.M5M_19205	3.34e-75	239.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1J4DZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
k59_1126305_1	314264.ROS217_00645	7.22e-36	129.0	COG1024@1|root,COG1024@2|Bacteria,1Q51H@1224|Proteobacteria,2TUPH@28211|Alphaproteobacteria,46RNI@74030|Roseovarius	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
k59_1086149_1	1121405.dsmv_2228	6.91e-44	157.0	28J96@1|root,2Z947@2|Bacteria,1R6TE@1224|Proteobacteria,42PZG@68525|delta/epsilon subdivisions,2WIKY@28221|Deltaproteobacteria,2MHY0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Oligopeptide transporter OPT superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
k59_303934_1	187272.Mlg_2407	3.17e-22	102.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1WX8V@135613|Chromatiales	135613|Chromatiales	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
k59_109917_1	998674.ATTE01000001_gene521	1.09e-62	201.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,4607M@72273|Thiotrichales	72273|Thiotrichales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
k59_264982_1	10181.XP_004844413.1	5.44e-184	565.0	COG1204@1|root,KOG0951@2759|Eukaryota,3ARV9@33154|Opisthokonta,3BYCJ@33208|Metazoa,3CW5J@33213|Bilateria,489T7@7711|Chordata,492SX@7742|Vertebrata,3JD8Y@40674|Mammalia,35AF1@314146|Euarchontoglires,4PUVQ@9989|Rodentia	33208|Metazoa	A	ATP-dependent RNA helicase activity	SNRNP200	GO:0000003,GO:0000245,GO:0000354,GO:0000375,GO:0000377,GO:0000381,GO:0000398,GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005682,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0007276,GO:0007283,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0008380,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019953,GO:0022414,GO:0022607,GO:0022613,GO:0022618,GO:0030532,GO:0031323,GO:0031974,GO:0031981,GO:0032501,GO:0032504,GO:0032991,GO:0034622,GO:0034641,GO:0042623,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043484,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045292,GO:0046483,GO:0046540,GO:0048024,GO:0048232,GO:0048609,GO:0050684,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051704,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0070035,GO:0071013,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097525,GO:0097526,GO:0120114,GO:0140098,GO:1901360,GO:1902494,GO:1903311,GO:1990904	3.6.4.13	ko:K12854	ko03040,map03040	M00354,M00355	-	-	ko00000,ko00001,ko00002,ko01000,ko03041	-	-	-	DEAD,Helicase_C,Sec63
k59_185025_1	61853.ENSNLEP00000022949	3.5e-169	479.0	KOG4211@1|root,KOG4211@2759|Eukaryota,38B9D@33154|Opisthokonta,3BBKX@33208|Metazoa,3CRF2@33213|Bilateria,48148@7711|Chordata,493VX@7742|Vertebrata,3J6CQ@40674|Mammalia,35A9Q@314146|Euarchontoglires,4M8TE@9443|Primates	33208|Metazoa	A	single-stranded RNA binding	HNRNPF	GO:0000003,GO:0000375,GO:0000377,GO:0000398,GO:0000578,GO:0003002,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003729,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006397,GO:0006403,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0007028,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007310,GO:0007311,GO:0007314,GO:0007315,GO:0007316,GO:0007350,GO:0007351,GO:0007389,GO:0008134,GO:0008150,GO:0008152,GO:0008298,GO:0008358,GO:0008380,GO:0008543,GO:0008595,GO:0009611,GO:0009719,GO:0009790,GO:0009798,GO:0009880,GO:0009889,GO:0009948,GO:0009950,GO:0009952,GO:0009953,GO:0009987,GO:0009994,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0017025,GO:0019094,GO:0019219,GO:0019221,GO:0019222,GO:0019953,GO:0021700,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030154,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033036,GO:0034097,GO:0034248,GO:0034641,GO:0035282,GO:0035722,GO:0042060,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043484,GO:0044085,GO:0044237,GO:0044238,GO:0044344,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045451,GO:0046483,GO:0048468,GO:0048469,GO:0048477,GO:0048599,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051179,GO:0051246,GO:0051252,GO:0051276,GO:0051641,GO:0051704,GO:0051716,GO:0060255,GO:0060810,GO:0060811,GO:0065007,GO:0070013,GO:0070671,GO:0070727,GO:0070848,GO:0070887,GO:0071013,GO:0071310,GO:0071345,GO:0071349,GO:0071363,GO:0071495,GO:0071704,GO:0071774,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1902494,GO:1990904,GO:2000112	-	ko:K12898	-	-	-	-	ko00000,ko03041	-	-	-	RRM_1,zf-RNPHF
k59_303946_1	472759.Nhal_0844	1.83e-133	402.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1WWAN@135613|Chromatiales	135613|Chromatiales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
k59_811229_1	1205753.A989_01740	4.13e-08	53.5	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1X4GY@135614|Xanthomonadales	135614|Xanthomonadales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
k59_811229_2	1122201.AUAZ01000009_gene2825	2.07e-24	101.0	COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria,4689F@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	yigP	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
k59_343108_1	876044.IMCC3088_300	8.1e-36	130.0	COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,1RNWZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
k59_427581_1	9593.ENSGGOP00000017854	6.99e-162	455.0	COG1841@1|root,KOG3184@2759|Eukaryota,38EZ8@33154|Opisthokonta,3BD87@33208|Metazoa,3CWY4@33213|Bilateria,4848P@7711|Chordata,49236@7742|Vertebrata,3J23F@40674|Mammalia,35NJZ@314146|Euarchontoglires,4M9JX@9443|Primates,4N4BQ@9604|Hominidae	33208|Metazoa	J	Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus	RPL7	GO:0000184,GO:0000463,GO:0000470,GO:0000956,GO:0001889,GO:0002165,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007275,GO:0008097,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009791,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015934,GO:0016070,GO:0016071,GO:0016072,GO:0019222,GO:0019439,GO:0019538,GO:0019843,GO:0022613,GO:0022625,GO:0022626,GO:0030016,GO:0030017,GO:0031099,GO:0031100,GO:0031672,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034470,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0035073,GO:0035210,GO:0042254,GO:0042273,GO:0042802,GO:0042803,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044449,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0046983,GO:0048513,GO:0048519,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0060255,GO:0061008,GO:0065007,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:0097421,GO:0099080,GO:0099081,GO:0099512,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990904	-	ko:K02937	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30,Ribosomal_L30_N
k59_1086182_1	1163409.UUA_02881	4.88e-37	135.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,1SZZW@1236|Gammaproteobacteria,1X6NR@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
k59_1086182_2	1307437.J139_00380	1.34e-13	72.8	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,2Q0X9@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	GM	Polysaccharide biosynthesis protein	wbpM	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
k59_1086186_1	1033802.SSPSH_003548	2.22e-70	239.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
k59_265021_1	9606.ENSP00000356574	3.02e-176	509.0	KOG1731@1|root,KOG1731@2759|Eukaryota,38EPD@33154|Opisthokonta,3BAIN@33208|Metazoa,3CR62@33213|Bilateria,48319@7711|Chordata,48ZQF@7742|Vertebrata,3J3XS@40674|Mammalia,35C3T@314146|Euarchontoglires,4MBQZ@9443|Primates,4N30R@9604|Hominidae	33208|Metazoa	D	thiol oxidase activity	QSOX1	GO:0000003,GO:0000139,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002576,GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005788,GO:0005794,GO:0006457,GO:0006464,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010506,GO:0010507,GO:0012505,GO:0016020,GO:0016021,GO:0016192,GO:0016241,GO:0016242,GO:0016491,GO:0016667,GO:0016670,GO:0016853,GO:0016860,GO:0016864,GO:0016971,GO:0016972,GO:0019222,GO:0019538,GO:0030141,GO:0030173,GO:0031090,GO:0031091,GO:0031093,GO:0031224,GO:0031228,GO:0031300,GO:0031301,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0031984,GO:0032501,GO:0032504,GO:0032940,GO:0034774,GO:0034975,GO:0035580,GO:0036211,GO:0036230,GO:0042119,GO:0042581,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045171,GO:0045321,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0055114,GO:0060205,GO:0065007,GO:0070013,GO:0070062,GO:0070820,GO:0071704,GO:0097708,GO:0098588,GO:0098791,GO:0099503,GO:0140096,GO:1901564,GO:1903561,GO:1904724	1.8.3.2	ko:K10758	-	-	-	-	ko00000,ko01000	-	-	-	Evr1_Alr,Thioredoxin
k59_1049150_1	582899.Hden_3229	5.28e-154	442.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,3N66U@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5,6.2.1.9	ko:K01903,ko:K14067	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
k59_1126352_1	1121451.DESAM_20802	9.11e-83	262.0	COG2414@1|root,COG2414@2|Bacteria,1NT3Z@1224|Proteobacteria,42MU9@68525|delta/epsilon subdivisions,2WKD2@28221|Deltaproteobacteria,2M7YR@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
k59_1126362_2	1267005.KB911263_gene1278	2.12e-49	169.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2TR76@28211|Alphaproteobacteria,3N79Z@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	permease YjgP YjgQ	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
k59_343158_1	933262.AXAM01000025_gene3415	1.48e-75	240.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,2MHNX@213118|Desulfobacterales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
k59_185074_1	83406.HDN1F_34750	3.8e-17	85.9	COG3156@1|root,COG3156@2|Bacteria,1RBNV@1224|Proteobacteria	1224|Proteobacteria	U	Type II secretion system protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
k59_227616_1	395493.BegalDRAFT_0413	5.13e-100	313.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,45ZTI@72273|Thiotrichales	72273|Thiotrichales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
k59_1086233_1	1528106.JRJE01000031_gene3673	2.68e-105	322.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TRX9@28211|Alphaproteobacteria,2JQ1W@204441|Rhodospirillales	204441|Rhodospirillales	E	FAD dependent oxidoreductase	ordL	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
k59_265067_1	1250232.JQNJ01000001_gene1766	7.73e-29	117.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1HY9H@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
k59_1205191_1	215803.DB30_4149	5.56e-108	326.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42QA7@68525|delta/epsilon subdivisions,2WM2Q@28221|Deltaproteobacteria,2YZTN@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
k59_578086_1	1122176.KB903553_gene3640	2.93e-72	234.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1IP67@117747|Sphingobacteriia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
k59_427672_1	570967.JMLV01000014_gene2042	1.23e-105	341.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2JPRP@204441|Rhodospirillales	204441|Rhodospirillales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
k59_1086288_1	82654.Pse7367_1013	3.51e-82	268.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1H71S@1150|Oscillatoriales	1117|Cyanobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
k59_655298_1	1415754.JQMK01000005_gene1826	1.55e-88	267.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,465JZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_695435_1	1173023.KE650771_gene5513	1.59e-32	129.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
k59_383593_1	1294273.roselon_01608	4.26e-60	196.0	COG4782@1|root,COG4782@2|Bacteria,1R573@1224|Proteobacteria,2U4A1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
k59_146102_1	161156.JQKW01000011_gene1030	1.76e-54	190.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,2GH8K@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
k59_427736_1	926550.CLDAP_34540	1.86e-05	52.8	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
k59_1205291_1	379731.PST_1557	2e-110	332.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1YZY1@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
k59_1205293_2	335543.Sfum_2794	1.49e-73	232.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MQ4Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase alpha subunit	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
k59_655368_1	163164.WD_0740	1.1e-99	302.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,2TQMA@28211|Alphaproteobacteria,47F4N@766|Rickettsiales	766|Rickettsiales	C	COG1271 Cytochrome bd-type quinol oxidase, subunit 1	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
k59_1247606_1	553207.HMPREF0299_5159	1.06e-08	61.6	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,22JIY@1653|Corynebacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
k59_734391_1	933262.AXAM01000009_gene1476	2.58e-96	303.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,2MIKT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
k59_655399_1	394503.Ccel_2950	6.43e-20	84.0	COG2963@1|root,COG2963@2|Bacteria,1VGE3@1239|Firmicutes,25BE4@186801|Clostridia,36WFJ@31979|Clostridiaceae	186801|Clostridia	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
k59_655399_2	261292.Nit79A3_2501	1.89e-36	133.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHC7@28216|Betaproteobacteria,374M1@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Integrase, catalytic core	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
k59_1086383_1	87626.PTD2_02101	1.77e-25	106.0	COG0845@1|root,COG0845@2|Bacteria,1NQDN@1224|Proteobacteria,1RRFE@1236|Gammaproteobacteria,2Q0KQ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG0845 Membrane-fusion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
k59_1086383_2	1453501.JELR01000001_gene3146	5.36e-20	85.5	COG1136@1|root,COG1136@2|Bacteria,1NHCD@1224|Proteobacteria,1RNIX@1236|Gammaproteobacteria,464FN@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ABC transporter	ycfV	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
k59_499756_1	1131813.AQVT01000001_gene1000	3e-64	218.0	COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,2TWGB@28211|Alphaproteobacteria,1JSC2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
k59_110173_1	1121924.ATWH01000005_gene2839	6.79e-27	108.0	COG3677@1|root,COG3677@2|Bacteria,2IF2C@201174|Actinobacteria,4FTAG@85023|Microbacteriaceae	201174|Actinobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
k59_970650_2	1121015.N789_12830	2.56e-43	150.0	COG3000@1|root,COG3000@2|Bacteria,1R4RM@1224|Proteobacteria,1SAME@1236|Gammaproteobacteria,1XA9M@135614|Xanthomonadales	135614|Xanthomonadales	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
k59_1086426_1	1442599.JAAN01000030_gene2146	2.66e-52	183.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1X4Q2@135614|Xanthomonadales	135614|Xanthomonadales	S	transporter	oliA	-	-	-	-	-	-	-	-	-	-	-	OPT
k59_972680_1	273068.TTE1708	6.59e-85	269.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,42EP3@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
k59_736417_1	1380387.JADM01000004_gene2876	2.77e-68	219.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XI4U@135619|Oceanospirillales	135619|Oceanospirillales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
k59_580055_2	290402.Cbei_2152	8.69e-09	56.6	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,36EGZ@31979|Clostridiaceae	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.6.99.1	ko:K00354	-	-	R00282	RC00001	ko00000,ko01000	-	-	-	Oxidored_FMN
k59_972685_2	32057.KB217478_gene1416	5.49e-59	195.0	COG0564@1|root,COG0564@2|Bacteria,1G0FD@1117|Cyanobacteria,1HJDP@1161|Nostocales	1117|Cyanobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
k59_229782_1	1116375.VEJY3_20801	3.66e-55	189.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,1RMF9@1236|Gammaproteobacteria,1XURY@135623|Vibrionales	135623|Vibrionales	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
k59_1249633_1	159087.Daro_1547	2.38e-59	203.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,2KU6T@206389|Rhodocyclales	206389|Rhodocyclales	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
k59_1207328_1	211586.SO_1777	1.25e-52	177.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RZUI@1236|Gammaproteobacteria,2QAN2@267890|Shewanellaceae	1236|Gammaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
k59_972712_2	1116472.MGMO_116c00040	4.41e-68	209.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XEKU@135618|Methylococcales	135618|Methylococcales	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
k59_619737_1	30611.ENSOGAP00000009024	6.56e-164	461.0	COG0098@1|root,KOG0877@2759|Eukaryota,38F84@33154|Opisthokonta,3BB55@33208|Metazoa,3CVYE@33213|Bilateria,486YZ@7711|Chordata,48ZDQ@7742|Vertebrata,3J6ZV@40674|Mammalia,359WY@314146|Euarchontoglires,4M6AX@9443|Primates	33208|Metazoa	J	Belongs to the universal ribosomal protein uS5 family	RPS2	GO:0000028,GO:0000184,GO:0000956,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009636,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010604,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0017134,GO:0019222,GO:0019439,GO:0019538,GO:0019838,GO:0019899,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0031396,GO:0031398,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032991,GO:0033036,GO:0033365,GO:0034097,GO:0034470,GO:0034613,GO:0034622,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0042493,GO:0042886,GO:0043043,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045047,GO:0045184,GO:0045471,GO:0046483,GO:0046677,GO:0046700,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0051438,GO:0051443,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070670,GO:0070727,GO:0070887,GO:0070925,GO:0070972,GO:0071310,GO:0071345,GO:0071353,GO:0071702,GO:0071704,GO:0071705,GO:0071826,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0080090,GO:0090150,GO:0090304,GO:0097159,GO:0097305,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901700,GO:1903320,GO:1903322,GO:1990904	-	ko:K02981	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
k59_972720_1	1127673.GLIP_1537	1.89e-73	235.0	COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,1RRNW@1236|Gammaproteobacteria,464IV@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
k59_30953_2	1038858.AXBA01000039_gene5123	3.47e-14	71.6	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2TR7N@28211|Alphaproteobacteria,3EXV1@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	helicase superfamily c-terminal domain	mgpS	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C
k59_657337_1	1121447.JONL01000004_gene2801	1.38e-59	201.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42NUP@68525|delta/epsilon subdivisions,2WKSD@28221|Deltaproteobacteria,2M9AZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-1	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
k59_148253_1	177437.HRM2_07800	2.7e-68	219.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria,2MKDA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
k59_385747_1	4432.XP_010271743.1	4.42e-31	121.0	COG3338@1|root,KOG0382@2759|Eukaryota,37PD6@33090|Viridiplantae,3GGS7@35493|Streptophyta	35493|Streptophyta	P	carbonic anhydrase	-	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase
k59_345383_2	335543.Sfum_3643	2.32e-53	179.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria,2MQBU@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
k59_112203_1	1123236.KB899380_gene2792	3.29e-40	142.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,466TA@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_0104	CoaE
k59_112203_2	1026882.MAMP_01427	3.91e-05	45.4	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,460VI@72273|Thiotrichales	72273|Thiotrichales	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
k59_619766_1	1532558.JL39_02220	5.86e-23	96.7	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria,4B7U3@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	response regulator	ompR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
k59_893489_1	1121937.AUHJ01000008_gene2013	4.22e-21	93.2	2BWJV@1|root,32U7J@2|Bacteria,1N47S@1224|Proteobacteria,1SAYP@1236|Gammaproteobacteria,468PF@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Frag1
k59_112223_1	411474.COPEUT_01102	0.000609	47.8	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
## 7298 queries scanned
## Total time (seconds): 90.10268688201904
## Rate: 81.00 q/s