## Fri Jan 3 03:08:17 2025 ## emapper-2.1.12 ## /data/home/zhuyingjie/miniforge3/envs/eggnog/bin/emapper.py -i /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/mmseqs_cluster/PRJNA947344/SRR24201529/SRR24201529_p_cluster_rep_seq.fasta --output PRJNA947344_SRR24201529 --data_dir /data/software/eggnog_database -m diamond --sensmode fast --output_dir /data/home/zhuyingjie/01_Project/01_metagenome/mangrove/annotation --temp_dir /data/software/eggnog_database/temp --excel --dbmem --cpu 24 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs k59_274318_1 1163408.UU9_14720 5.23e-86 264.0 COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1X4BE@135614|Xanthomonadales 135614|Xanthomonadales O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK k59_413493_1 1229909.NSED_09250 2.51e-52 169.0 arCOG08776@1|root,arCOG08776@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_413493_2 1229909.NSED_09255 1.04e-27 101.0 arCOG08769@1|root,arCOG08769@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_224309_1 1163408.UU9_03198 1.87e-107 328.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1X498@135614|Xanthomonadales 135614|Xanthomonadales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tktA - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k59_63893_1 1442599.JAAN01000003_gene1089 1.12e-19 100.0 COG2911@1|root,COG2982@1|root,COG2911@2|Bacteria,COG2982@2|Bacteria,1QXZF@1224|Proteobacteria,1T55Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria M haemagglutination activity domain - - - - - - - - - - - - ESPR,Haemagg_act k59_1515460_1 1229909.NSED_02790 1.61e-84 256.0 COG0169@1|root,arCOG01033@2157|Archaea,41S6G@651137|Thaumarchaeota 651137|Thaumarchaeota E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N k59_814215_2 1500893.JQNB01000001_gene1000 2.33e-71 228.0 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,1RNTG@1236|Gammaproteobacteria,1X4BB@135614|Xanthomonadales 135614|Xanthomonadales EGP major facilitator superfamily emrB - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 k59_1515470_1 1500893.JQNB01000001_gene2900 5.64e-94 297.0 COG4774@1|root,COG4774@2|Bacteria,1NR6X@1224|Proteobacteria,1T22H@1236|Gammaproteobacteria 1236|Gammaproteobacteria P TonB-dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_15469_1 1163409.UUA_05063 2.37e-31 119.0 COG0745@1|root,COG0745@2|Bacteria,1RHTT@1224|Proteobacteria,1T1MZ@1236|Gammaproteobacteria,1X6CU@135614|Xanthomonadales 135614|Xanthomonadales T COG0784 FOG CheY-like receiver - - - - - - - - - - - - Hpt,Response_reg k59_15469_2 666685.R2APBS1_2232 4.3e-19 85.1 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1X30R@135614|Xanthomonadales 135614|Xanthomonadales L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k59_1375366_1 1234364.AMSF01000063_gene2249 7.45e-107 332.0 COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,1MUA6@1224|Proteobacteria,1SZXB@1236|Gammaproteobacteria,1X4T0@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the Orn Lys Arg decarboxylase class-II family lysA - 2.7.2.4,4.1.1.20 ko:K12526 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00451,R00480 RC00002,RC00043,RC00299 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC k59_1465721_1 1499686.BN1079_00327 3.1e-56 186.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria 1236|Gammaproteobacteria E aminotransferase argD GO:0003674,GO:0003824,GO:0003992,GO:0004069,GO:0005488,GO:0005515,GO:0006082,GO:0006105,GO:0006520,GO:0006525,GO:0006526,GO:0006527,GO:0006553,GO:0006591,GO:0006593,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009016,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009067,GO:0009084,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0017144,GO:0019545,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0036094,GO:0042450,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043825,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.11,2.6.1.17,2.6.1.81 ko:K00821,ko:K00840 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04217,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - iAPECO1_1312.APECO1_817,iEC55989_1330.EC55989_1916,iECABU_c1320.ECABU_c20050,iECED1_1282.ECED1_1950,iECOK1_1307.ECOK1_1868,iECP_1309.ECP_1694,iECS88_1305.ECS88_1800,iEcSMS35_1347.EcSMS35_1443,iSFV_1184.SFV_3365,iSF_1195.SF3378,iSFxv_1172.SFxv_3689,iSSON_1240.SSON_3490,iS_1188.S4385,iUMN146_1321.UM146_08405,iUTI89_1310.UTI89_C1943,ic_1306.c2148 Aminotran_3 k59_124686_3 269482.Bcep1808_1314 3.64e-31 117.0 COG4678@1|root,COG4678@2|Bacteria,1R92U@1224|Proteobacteria,2VUZ6@28216|Betaproteobacteria,1KDHZ@119060|Burkholderiaceae 28216|Betaproteobacteria G PFAM glycoside hydrolase family 24 - - - - - - - - - - - - Phage_lysozyme k59_713777_2 1454004.AW11_02765 9.18e-18 86.3 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2WEJE@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase cpxA - 2.7.13.3 ko:K02484,ko:K07640,ko:K07642 ko01503,ko02020,map01503,map02020 M00447,M00450,M00645,M00646,M00648,M00727,M00728 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k59_15599_1 572265.HDEF_2187 1.43e-06 58.5 COG4675@1|root,COG5301@1|root,COG4675@2|Bacteria,COG5301@2|Bacteria,1RDJW@1224|Proteobacteria,1S415@1236|Gammaproteobacteria 1236|Gammaproteobacteria S tail collar domain protein - - - - - - - - - - - - Collar,Phage_fiber_2 k59_15599_2 1112217.PPL19_22937 1.32e-47 160.0 COG4385@1|root,COG4385@2|Bacteria,1NZST@1224|Proteobacteria,1RQRK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S tail protein I - - - - - - - - - - - Tail_P2_I k59_513801_1 1229909.NSED_03770 2.52e-10 59.3 arCOG08757@1|root,arCOG08757@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_315351_1 287.DR97_4100 2.52e-116 346.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1YEP0@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027 CBS,IMPDH,NMO k59_1314310_1 930169.B5T_03996 5.36e-61 196.0 COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1RY9N@1236|Gammaproteobacteria,1XKZ2@135619|Oceanospirillales 135619|Oceanospirillales K IclR family transcriptional regulator - - - ko:K02624,ko:K13641,ko:K20539 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_IclR,IclR k59_274962_2 1224318.DT73_18440 3.11e-56 181.0 COG1811@1|root,COG1811@2|Bacteria,1MX1D@1224|Proteobacteria,1RYSH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane yqgA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07150 - - - - ko00000 - - - DUF554 k59_294623_1 1234364.AMSF01000036_gene283 4.3e-83 273.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1X3T3@135614|Xanthomonadales 135614|Xanthomonadales EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF - 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase k59_1394452_1 1121106.JQKB01000008_gene1419 2.66e-13 68.9 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2JQKF@204441|Rhodospirillales 204441|Rhodospirillales C III protein, CoA-transferase family - - - - - - - - - - - - CoA_transf_3 k59_1394452_2 395965.Msil_3301 5.75e-14 72.8 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2U1G1@28211|Alphaproteobacteria,3NAGT@45404|Beijerinckiaceae 28211|Alphaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - HTH_Crp_2,cNMP_binding k59_828232_1 666685.R2APBS1_0626 9.48e-154 461.0 COG1629@1|root,COG4772@1|root,COG1629@2|Bacteria,COG4772@2|Bacteria,1MWTT@1224|Proteobacteria,1RRQ9@1236|Gammaproteobacteria,1X33Z@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug k59_577165_1 264198.Reut_A1827 1.39e-44 160.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VKM4@28216|Betaproteobacteria,1K523@119060|Burkholderiaceae 28216|Betaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 k59_1077426_1 436308.Nmar_1034 3.95e-131 382.0 COG5256@1|root,arCOG01561@2157|Archaea,41SD2@651137|Thaumarchaeota 651137|Thaumarchaeota J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K03231 ko03013,ko05134,map03013,map05134 - - - ko00000,ko00001,ko03012,ko03016,ko03019,ko04131,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k59_480762_1 1234364.AMSF01000015_gene3278 7.79e-104 308.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,1X5UT@135614|Xanthomonadales 135614|Xanthomonadales O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03767 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase k59_1594663_1 1459636.NTE_03443 0.000195 43.1 COG1146@1|root,arCOG04548@2157|Archaea,41SI0@651137|Thaumarchaeota 651137|Thaumarchaeota C PFAM 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4 k59_1594663_2 436308.Nmar_0240 2.6e-39 139.0 COG0470@1|root,arCOG00469@2157|Archaea,41SFJ@651137|Thaumarchaeota 651137|Thaumarchaeota L Replication factor C - - - ko:K04801 ko03030,map03030 - - - ko00000,ko00001,ko03032 - - - DNA_pol3_delta2,Rep_fac_C,RuvB_N k59_244413_1 748247.AZKH_3965 3.28e-39 149.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KVQE@206389|Rhodocyclales 206389|Rhodocyclales T chemotaxis protein - - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k59_29137_1 666685.R2APBS1_2183 2e-114 338.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,1RMXZ@1236|Gammaproteobacteria,1X491@135614|Xanthomonadales 135614|Xanthomonadales I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE k59_29137_2 680646.RMDY18_16690 3.04e-20 87.8 COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,1W7UF@1268|Micrococcaceae 201174|Actinobacteria S PFAM aldo keto reductase dkgA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red k59_144926_1 1234364.AMSF01000085_gene2864 1.15e-80 242.0 COG4539@1|root,COG4539@2|Bacteria,1N1G8@1224|Proteobacteria,1S9FD@1236|Gammaproteobacteria,1X6EP@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - - - - - - - - - - DUF962 k59_1394920_1 330214.NIDE0407 6.55e-83 268.0 COG0155@1|root,COG0425@1|root,COG0155@2|Bacteria,COG0425@2|Bacteria,3J11D@40117|Nitrospirae 40117|Nitrospirae C Nitrite and sulphite reductase 4Fe-4S domain - - 1.7.1.15,1.8.7.1 ko:K00362,ko:K00392 ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120 M00176,M00530 R00787,R00859,R03600 RC00065,RC00176 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr k59_1394959_1 436308.Nmar_1186 3.55e-34 125.0 arCOG08642@1|root,arCOG08642@2157|Archaea,41T1T@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_330730_1 1163409.UUA_01734 8.87e-16 77.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1X4MI@135614|Xanthomonadales 135614|Xanthomonadales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k59_330730_2 666685.R2APBS1_3295 3.61e-153 441.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1X33V@135614|Xanthomonadales 135614|Xanthomonadales H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD k59_1427308_1 585529.HMPREF0291_11209 0.000167 46.2 COG1028@1|root,COG1028@2|Bacteria,2GJCZ@201174|Actinobacteria,22JI6@1653|Corynebacteriaceae 201174|Actinobacteria IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k59_1427308_2 1366050.N234_12310 2.44e-18 83.2 COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,2WH24@28216|Betaproteobacteria,1K5AI@119060|Burkholderiaceae 28216|Betaproteobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6 k59_1427374_1 1437882.AZRU01000037_gene4397 8.22e-163 474.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1YD3X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k59_677785_1 1005048.CFU_0765 5.65e-26 99.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2VU6T@28216|Betaproteobacteria,474V1@75682|Oxalobacteraceae 28216|Betaproteobacteria U Preprotein translocase subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k59_677785_2 1231391.AMZF01000027_gene399 9.55e-32 124.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,3T1QM@506|Alcaligenaceae 28216|Betaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k59_295420_1 1163407.UU7_12968 2.23e-62 214.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,1X3TQ@135614|Xanthomonadales 135614|Xanthomonadales M aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k59_1028039_1 292.DM42_3196 6.4e-83 257.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,1K03I@119060|Burkholderiaceae 28216|Betaproteobacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N k59_78497_1 436308.Nmar_0736 3.52e-38 132.0 arCOG08802@1|root,arCOG08802@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_1395230_1 118797.XP_007468251.1 1.45e-88 290.0 COG0085@1|root,KOG0214@2759|Eukaryota 2759|Eukaryota K DNA-directed 5'-3' RNA polymerase activity rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043,ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k59_727547_1 1163408.UU9_02204 6.75e-89 275.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1X3YG@135614|Xanthomonadales 135614|Xanthomonadales T Fis family transcriptional regulator fleQ - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - FleQ,HTH_8,Sigma54_activat k59_245170_1 1500893.JQNB01000001_gene1964 1.81e-49 164.0 COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,1RNH2@1236|Gammaproteobacteria,1X4C7@135614|Xanthomonadales 135614|Xanthomonadales IQ Belongs to the short-chain dehydrogenases reductases (SDR) family phbB - 1.1.1.36 ko:K00023 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R01779,R01977 RC00103,RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short,adh_short_C2 k59_481323_2 1163407.UU7_12134 1.2e-33 127.0 COG3126@1|root,COG3126@2|Bacteria,1QSY6@1224|Proteobacteria,1RWK7@1236|Gammaproteobacteria,1X42E@135614|Xanthomonadales 135614|Xanthomonadales S Type III secretion system lipoprotein chaperone (YscW) - - - ko:K09914 - - - - ko00000 - - - DUF1481,YscW k59_1028132_1 1163408.UU9_14170 8.92e-107 324.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1SZUM@1236|Gammaproteobacteria,1X325@135614|Xanthomonadales 135614|Xanthomonadales S ABC transporter substrate-binding protein - - - - - - - - - - - - ABC1 k59_1395460_1 740709.A10D4_05272 9.68e-23 101.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 k59_331103_1 290512.Paes_0629 1.95e-80 251.0 COG3344@1|root,COG3344@2|Bacteria 2|Bacteria L reverse transcriptase - - - - - - - - - - - - GIIM,RVT_1 k59_1328681_1 93220.LV28_00490 4.44e-54 181.0 COG0604@1|root,COG0604@2|Bacteria,1MU4N@1224|Proteobacteria,2VIU4@28216|Betaproteobacteria,1JZTH@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily - - 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N_2 k59_1477762_1 1163408.UU9_10669 3.33e-107 321.0 COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1SKNI@1236|Gammaproteobacteria,1X5G2@135614|Xanthomonadales 135614|Xanthomonadales J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His k59_1477790_2 84531.JMTZ01000007_gene3405 3.44e-86 271.0 COG3182@1|root,COG3182@2|Bacteria,1MVET@1224|Proteobacteria,1RNR9@1236|Gammaproteobacteria,1X4KJ@135614|Xanthomonadales 135614|Xanthomonadales S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM k59_1279204_1 157783.LK03_10770 2.45e-153 444.0 COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2574,iBWG_1329.BWG_2338,iECDH10B_1368.ECDH10B_2742,iECDH1ME8569_1439.ECDH1ME8569_2501,iETEC_1333.ETEC_2787,iEcDH1_1363.EcDH1_1094,iJO1366.b2574,iJR904.b2574,iLF82_1304.LF82_1433,iNRG857_1313.NRG857_12785,iY75_1357.Y75_RS13445,iYL1228.KPN_02899 FAD_binding_2,Succ_DH_flav_C k59_1028445_1 1131451.O1K_06352 1.3e-50 177.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,1RN5F@1236|Gammaproteobacteria,1X2XY@135614|Xanthomonadales 135614|Xanthomonadales C Malic enzyme maeB - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malate_DH,Malic_M,PTA_PTB,malic k59_1028445_2 767434.Fraau_2698 1.33e-43 157.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1X3YZ@135614|Xanthomonadales 135614|Xanthomonadales C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k59_727921_1 1286631.X805_13200 1.06e-49 166.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,1KJRR@119065|unclassified Burkholderiales 28216|Betaproteobacteria L exodeoxyribonuclease III xthA - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos k59_1328895_1 713586.KB900536_gene2967 2.99e-79 259.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales 135613|Chromatiales K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k59_928373_1 1254432.SCE1572_19005 2.1e-89 274.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YUHC@29|Myxococcales 28221|Deltaproteobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k59_631872_1 330214.NIDE0498 3.57e-41 148.0 COG1322@1|root,COG1322@2|Bacteria,3J15T@40117|Nitrospirae 40117|Nitrospirae S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC k59_631872_2 330214.NIDE0499 3.26e-48 157.0 COG4696@1|root,COG4696@2|Bacteria 2|Bacteria J Protein conserved in bacteria XK27_03185 - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - Acetyltransf_3,Hydrolase_3,PRA-PH k59_146160_1 1234364.AMSF01000024_gene3809 8.53e-65 201.0 COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,1X7NG@135614|Xanthomonadales 135614|Xanthomonadales U Biopolymer transport protein tolR - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD k59_146160_2 1234364.AMSF01000024_gene3810 6.39e-33 121.0 COG3064@1|root,COG3064@2|Bacteria,1RKZU@1224|Proteobacteria,1S72T@1236|Gammaproteobacteria,1X3C2@135614|Xanthomonadales 135614|Xanthomonadales M Membrane protein TolA tolA - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TonB_2 k59_1427979_1 1182590.BN5_02139 6.3e-38 135.0 COG0834@1|root,COG0834@2|Bacteria,1RAPU@1224|Proteobacteria,1S3HX@1236|Gammaproteobacteria,1YD1G@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria ET Amino acid ABC transporter substrate-binding protein - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k59_1396035_1 926554.KI912633_gene3997 1.12e-41 152.0 COG3940@1|root,COG3940@2|Bacteria,1WMFV@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G Glycosyl hydrolases family 43 - - - - - - - - - - - - Glyco_hydro_43 k59_578278_1 391735.Veis_0892 6.6e-86 264.0 COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VK3Y@28216|Betaproteobacteria,4AGID@80864|Comamonadaceae 28216|Betaproteobacteria G PFAM D-galactarate dehydratase Altronate hydrolase domain protein - - 4.4.1.24 ko:K16846 ko00270,map00270 - R07633 RC01785 ko00000,ko00001,ko01000 - - - GD_AH_C k59_1279431_1 671143.DAMO_2755 1.07e-59 203.0 COG0568@1|root,COG0568@2|Bacteria,2NNY9@2323|unclassified Bacteria 2|Bacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_829481_1 1354722.JQLS01000004_gene4233 9.24e-164 473.0 COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,2U39P@28211|Alphaproteobacteria 28211|Alphaproteobacteria I TIGRFAM methylmalonyl-CoA mutase, large subunit - - 5.4.99.2 ko:K01848 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase k59_1530053_1 998088.B565_3697 2.19e-90 288.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1Y4Z8@135624|Aeromonadales 135624|Aeromonadales S transport system, fused permease components - - - - - - - - - - - - DUF3394,DctM k59_1059339_1 1123060.JONP01000009_gene1954 2.26e-07 52.8 COG0667@1|root,COG0667@2|Bacteria,1MWGQ@1224|Proteobacteria,2TUJ8@28211|Alphaproteobacteria,2JVBV@204441|Rhodospirillales 204441|Rhodospirillales C Aldo/keto reductase family - - 1.1.1.122 ko:K00064 ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120 M00114 R07675,R08926 RC00066,RC00161 ko00000,ko00001,ko00002,ko01000 - - - Aldo_ket_red k59_1460262_1 1229909.NSED_00070 1.54e-70 234.0 COG1287@1|root,arCOG02044@2157|Archaea,41SBI@651137|Thaumarchaeota 651137|Thaumarchaeota G Oligosaccharyl transferase STT3 subunit - - 2.4.99.18 ko:K07151 ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141 M00072 R04216,R05976 RC00005,RC00482 ko00000,ko00001,ko00002,ko01000,ko01003 - GT66 - STT3 k59_1109098_1 436308.Nmar_0369 4.03e-105 312.0 COG1063@1|root,arCOG01459@2157|Archaea 2157|Archaea C Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,Glu_dehyd_C k59_1009010_1 323848.Nmul_A1036 2.2e-91 283.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,371XE@32003|Nitrosomonadales 28216|Betaproteobacteria U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN k59_1366959_1 477228.YO5_05674 7.52e-107 310.0 COG5516@1|root,COG5516@2|Bacteria,1REGN@1224|Proteobacteria,1S4CQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding - - - - - - - - - - - - ABATE,zf-CGNR k59_116129_1 1234364.AMSF01000016_gene1706 1.84e-107 328.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,1X4P1@135614|Xanthomonadales 135614|Xanthomonadales O Cytochrome C biogenesis ccmF1 - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm k59_216153_1 1207058.L53_02950 2.45e-35 134.0 COG2807@1|root,COG2807@2|Bacteria,1Q8U3@1224|Proteobacteria,2V7A4@28211|Alphaproteobacteria,43ZF9@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k59_558787_1 330214.NIDE4386 2.33e-115 346.0 COG1009@1|root,COG1009@2|Bacteria,3J0AN@40117|Nitrospirae 40117|Nitrospirae CP NADH-quinone oxidoreductase - - 1.6.5.3 ko:K00341,ko:K05577 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k59_1367159_1 1500893.JQNB01000001_gene1023 3.98e-52 187.0 COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,1X54E@135614|Xanthomonadales 135614|Xanthomonadales M rhs family - - - - - - - - - - - - RHS_repeat k59_1410525_1 745411.B3C1_11574 5.38e-83 251.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1J4H7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iAF1260.b1093,iAPECO1_1312.APECO1_174,iBWG_1329.BWG_0941,iE2348C_1286.E2348C_1185,iEC55989_1330.EC55989_1205,iECABU_c1320.ECABU_c13060,iECDH10B_1368.ECDH10B_1165,iECDH1ME8569_1439.ECDH1ME8569_1028,iECED1_1282.ECED1_1236,iECIAI39_1322.ECIAI39_2068,iECNA114_1301.ECNA114_1150,iECO103_1326.ECO103_1138,iECOK1_1307.ECOK1_1200,iECP_1309.ECP_1085,iECS88_1305.ECS88_1107,iECSE_1348.ECSE_1157,iECSF_1327.ECSF_0992,iECUMN_1333.ECUMN_1268,iECW_1372.ECW_m1201,iEKO11_1354.EKO11_2741,iETEC_1333.ETEC_1158,iEcDH1_1363.EcDH1_2554,iEcE24377_1341.EcE24377A_1214,iEcHS_1320.EcHS_A1215,iEcSMS35_1347.EcSMS35_2034,iEcolC_1368.EcolC_2508,iG2583_1286.G2583_1353,iJN746.PP_1914,iJO1366.b1093,iJR904.b1093,iSBO_1134.SBO_1970,iSFV_1184.SFV_1113,iSF_1195.SF1097,iSFxv_1172.SFxv_1249,iSSON_1240.SSON_1113,iS_1188.S1177,iSbBS512_1146.SbBS512_E2231,iUMN146_1321.UM146_11860,iUMNK88_1353.UMNK88_1363,iUTI89_1310.UTI89_C1218,iWFL_1372.ECW_m1201,iY75_1357.Y75_RS05710 adh_short_C2 k59_1410525_2 1070319.CAGGBEG34_180078 6.74e-07 50.8 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,1K35C@119060|Burkholderiaceae 28216|Betaproteobacteria I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15355 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 k59_758976_1 1415780.JPOG01000001_gene3229 1.1e-17 84.3 COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1SD3J@1236|Gammaproteobacteria,1X471@135614|Xanthomonadales 135614|Xanthomonadales D Cell division protein - - - - - - - - - - - - SPOR k59_266423_1 1163408.UU9_14400 7.03e-98 289.0 COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,1S4MG@1236|Gammaproteobacteria,1X4H4@135614|Xanthomonadales 135614|Xanthomonadales S Alpha beta - - - ko:K07018 - - - - ko00000 - - - Hydrolase_4,Peptidase_S15 k59_459738_1 745411.B3C1_16922 3.26e-77 249.0 COG5001@1|root,COG5001@2|Bacteria,1R8FX@1224|Proteobacteria,1RNII@1236|Gammaproteobacteria,1J87U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3 k59_266450_1 543728.Vapar_4371 2.57e-50 171.0 COG0583@1|root,COG0583@2|Bacteria,1MWUP@1224|Proteobacteria,2VJPA@28216|Betaproteobacteria,4AABJ@80864|Comamonadaceae 28216|Betaproteobacteria K Transcriptional regulator iciA - - ko:K05596 - - - - ko00000,ko03000,ko03036 - - - HTH_1,LysR_substrate k59_266471_1 1163409.UUA_02301 3.39e-86 278.0 COG1215@1|root,COG5309@1|root,COG1215@2|Bacteria,COG5309@2|Bacteria,1MWF8@1224|Proteobacteria,1RPJ6@1236|Gammaproteobacteria,1X4CR@135614|Xanthomonadales 135614|Xanthomonadales M Cellulose synthase catalytic subunit (UDP-forming) bcsA - 2.4.1.12 ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 - R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 - BcsB,Cellulose_synt,Glyco_hydro_17,Glyco_tranf_2_3,Glycos_transf_2,PilZ k59_609876_1 1218352.B597_006590 5.27e-116 348.0 COG0446@1|root,COG3453@1|root,COG0446@2|Bacteria,COG3453@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria,1Z2GC@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S protein conserved in bacteria sqrdl - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - DUF442,Pyr_redox_2 k59_266613_1 983917.RGE_25290 8.85e-32 123.0 COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKWX@28216|Betaproteobacteria,1KKAX@119065|unclassified Burkholderiales 28216|Betaproteobacteria I Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k59_266613_2 887898.HMPREF0551_2650 2.04e-13 69.7 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,1K2AX@119060|Burkholderiaceae 28216|Betaproteobacteria G Phosphoglycolate phosphatase gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k59_233704_23 351746.Pput_1922 1.31e-116 341.0 2DIG9@1|root,3036R@2|Bacteria,1RBPA@1224|Proteobacteria 1224|Proteobacteria L YqaJ-like viral recombinase domain - - 3.1.11.3 ko:K01143 - - - - ko00000,ko01000 - - - YqaJ k59_233704_24 940282.CADQ01000022_gene2093 3.64e-53 181.0 2CHRY@1|root,30Z9E@2|Bacteria,1RGQK@1224|Proteobacteria,2U9J0@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - RecT k59_233704_29 1429912.V5RC22_9CAUD 1.13e-46 154.0 4QEQK@10239|Viruses,4QUQ4@35237|dsDNA viruses no RNA stage,4QPEJ@28883|Caudovirales,4QMF2@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - k59_233704_31 1286170.RORB6_10270 2.04e-52 176.0 COG1974@1|root,COG1974@2|Bacteria,1RIY3@1224|Proteobacteria,1S2IC@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Repressor prpA - - - - - - - - - - - HTH_3,Peptidase_S24 k59_233704_36 1502852.FG94_04980 4.5e-71 230.0 COG3756@1|root,COG3756@2|Bacteria,1RFD3@1224|Proteobacteria,2VWCR@28216|Betaproteobacteria,4774S@75682|Oxalobacteraceae 28216|Betaproteobacteria S Protein of unknown function (DUF1376) - - - - - - - - - - - - DUF1376 k59_233704_37 688245.CtCNB1_2662 2.36e-18 89.4 2CTHS@1|root,32STJ@2|Bacteria,1N626@1224|Proteobacteria,2W0C3@28216|Betaproteobacteria,4AGVK@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_233704_40 1218074.BAXZ01000003_gene523 0.000709 45.8 2AF1F@1|root,314ZU@2|Bacteria,1PUYD@1224|Proteobacteria,2WAZT@28216|Betaproteobacteria,1K4QI@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_233704_47 1498011.A0A096XUU0_9CAUD 2.46e-142 423.0 4QG38@10239|Viruses,4QQVI@28883|Caudovirales,4QNWM@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_233704_49 1344012.ATMI01000052_gene1938 1.79e-158 470.0 28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,1RZ7H@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con k59_233704_57 421052.F945_01894 5.84e-10 63.9 28RDB@1|root,2ZDSP@2|Bacteria,1RBF9@1224|Proteobacteria,1RQ0W@1236|Gammaproteobacteria,3NMWA@468|Moraxellaceae 1236|Gammaproteobacteria S Tail tubular protein - - - - - - - - - - - - Tube k59_233704_58 1344012.ATMI01000056_gene1743 5.79e-179 538.0 28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,1RR0M@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_233704_59 1417599.U6C6Z0_9CAUD 8.09e-29 117.0 4QB55@10239|Viruses,4QW4S@35237|dsDNA viruses no RNA stage,4QSJ0@28883|Caudovirales,4QNGX@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - k59_820881_1 1399774.JDWH01000017_gene4155 1.04e-22 94.0 COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S8TQ@1236|Gammaproteobacteria,3X2HY@547|Enterobacter 1236|Gammaproteobacteria N flagellar protein FliS fliS GO:0001539,GO:0003674,GO:0005198,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - ko:K02422 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliS k59_622342_1 686578.AFFX01000003_gene204 6.35e-45 167.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k59_1271107_1 1163409.UUA_15693 7.68e-88 285.0 COG3537@1|root,COG3537@2|Bacteria,1N86N@1224|Proteobacteria,1RZCC@1236|Gammaproteobacteria,1X4Z0@135614|Xanthomonadales 135614|Xanthomonadales G Glycosyl hydrolase family 92 - - - - - - - - - - - - Glyco_hydro_92 k59_233920_2 1254432.SCE1572_50505 2.42e-15 79.7 COG2197@1|root,COG2197@2|Bacteria,1R4TP@1224|Proteobacteria,42UI0@68525|delta/epsilon subdivisions,2WQIQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Autoinducer binding domain - - - ko:K20334 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - Autoind_bind,GerE k59_1271132_1 1124983.PFLCHA0_c54630 2.86e-128 382.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,1RNQD@1236|Gammaproteobacteria,1YPJJ@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria F Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527 DXP_synthase_N,Transket_pyr,Transketolase_C k59_1121445_1 1163407.UU7_03977 1.12e-36 129.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria,1X7AR@135614|Xanthomonadales 135614|Xanthomonadales C Aerobic-type carbon monoxide dehydrogenase small subunit CoxS - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 k59_1121445_2 1163408.UU9_04482 8.41e-21 90.9 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria,1XBX9@135614|Xanthomonadales 135614|Xanthomonadales E amino acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 k59_184143_1 1144319.PMI16_03321 5.46e-77 234.0 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2VJPQ@28216|Betaproteobacteria,474PF@75682|Oxalobacteraceae 28216|Betaproteobacteria Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k59_1585038_1 1500890.JQNL01000001_gene319 3.33e-143 427.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RPSW@1236|Gammaproteobacteria,1X5RU@135614|Xanthomonadales 135614|Xanthomonadales G COG3957 Phosphoketolase - - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N k59_472545_1 331869.BAL199_20665 2.24e-50 167.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,4BS5M@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II k59_472545_2 1268622.AVS7_04235 4.05e-15 74.3 COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2VNPV@28216|Betaproteobacteria,4ABDT@80864|Comamonadaceae 28216|Betaproteobacteria I thiolase - - - - - - - - - - - - Thiolase_C k59_1020119_1 1234364.AMSF01000056_gene1176 4.35e-111 330.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1X2ZK@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e k59_234114_1 1163408.UU9_09267 6.91e-20 92.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RSN6@1236|Gammaproteobacteria,1X3V2@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k59_21914_1 1234364.AMSF01000005_gene778 1.9e-98 291.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1X459@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI k59_920416_1 1380355.JNIJ01000082_gene2162 2.92e-56 182.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TSGZ@28211|Alphaproteobacteria,3JUDN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L IS116 IS110 IS902 family - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k59_22045_1 1163407.UU7_02207 4.54e-99 290.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,1X340@135614|Xanthomonadales 135614|Xanthomonadales L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k59_134698_1 95619.PM1_0204690 1.3e-47 169.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria 1236|Gammaproteobacteria J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,RNB,S1 k59_1420273_1 767434.Fraau_3099 2.25e-18 84.7 COG3137@1|root,COG3137@2|Bacteria,1MWI4@1224|Proteobacteria,1RN4J@1236|Gammaproteobacteria,1X57Z@135614|Xanthomonadales 135614|Xanthomonadales M salt-induced outer membrane protein - - - ko:K07283 - - - - ko00000 - - - DUF481 k59_134732_1 1244869.H261_01552 1.3e-55 178.0 COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2UJSY@28211|Alphaproteobacteria 28211|Alphaproteobacteria C cytochrome c oxidase (Subunit II) - - - - - - - - - - - - - k59_134732_2 1123360.thalar_02883 2.59e-15 68.9 2ERCE@1|root,33IY3@2|Bacteria,1NNN9@1224|Proteobacteria,2UXY5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_968062_1 913325.N799_01705 3.39e-34 125.0 COG1569@1|root,COG1569@2|Bacteria,1NASM@1224|Proteobacteria,1T6M3@1236|Gammaproteobacteria,1X7RF@135614|Xanthomonadales 135614|Xanthomonadales S nucleic acid-binding protein, contains PIN domain - - - - - - - - - - - - PIN_3 k59_968062_2 1500893.JQNB01000001_gene252 1.42e-29 112.0 COG2186@1|root,COG2186@2|Bacteria,1MV83@1224|Proteobacteria,1RSDC@1236|Gammaproteobacteria,1X65D@135614|Xanthomonadales 135614|Xanthomonadales K FCD - - - - - - - - - - - - FCD,GntR k59_1472295_1 644801.Psest_4317 1.5e-122 357.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RPQC@1236|Gammaproteobacteria,1Z2FV@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S alcohol dehydrogenase adhA - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N k59_879489_1 1110697.NCAST_34_00340 3.49e-08 54.7 COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria,4FUAW@85025|Nocardiaceae 201174|Actinobacteria P ATPases associated with a variety of cellular activities mntA - - ko:K09820,ko:K11603,ko:K11607 ko02010,ko02020,map02010,map02020 M00243,M00316,M00317 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.1,3.A.1.15.7,3.A.1.15.9 - - ABC_tran k59_879489_2 436308.Nmar_1128 9.05e-46 157.0 COG0803@1|root,arCOG01005@2157|Archaea,41T29@651137|Thaumarchaeota 651137|Thaumarchaeota P Periplasmic solute binding protein - - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZnuA k59_516651_1 1230343.CANP01000046_gene3646 4.18e-09 55.8 2AGY4@1|root,33HSC@2|Bacteria,1NJ83@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_1380192_1 1229909.NSED_04240 1.25e-39 132.0 arCOG10546@1|root,arCOG10546@2157|Archaea,41SRD@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_516671_1 287.DR97_1211 0.000598 41.2 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1YDZV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Involved in DNA repair and RecF pathway recombination recO GO:0008150,GO:0009314,GO:0009628,GO:0050896 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k59_516671_2 95619.PM1_0216780 3.67e-104 305.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2564,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 PdxJ k59_1267758_1 1163409.UUA_10626 9.69e-72 239.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1X3A2@135614|Xanthomonadales 135614|Xanthomonadales P COG0474 Cation transport ATPase - - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase k59_1518460_1 95619.PM1_0202800 1.96e-21 85.1 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 k59_1518460_2 521719.ATXQ01000010_gene34 6.15e-28 100.0 COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1YGYV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 k59_318473_1 1234364.AMSF01000015_gene3342 3.83e-57 192.0 COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,1RQJY@1236|Gammaproteobacteria,1X3XV@135614|Xanthomonadales 135614|Xanthomonadales M Carboxypeptidase - - - - - - - - - - - - Peptidase_S10 k59_318473_2 1131553.JIBI01000002_gene1777 8.77e-34 120.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,3736W@32003|Nitrosomonadales 28216|Betaproteobacteria M Peptidyl-prolyl cis-trans isomerase fkpA - 5.2.1.8 ko:K01802,ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k59_67304_1 1109445.AGSX01000019_gene1729 6.36e-120 356.0 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,1RQAK@1236|Gammaproteobacteria,1Z0SC@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria C Isocitrate lyase aceA - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k59_468662_1 1163408.UU9_08932 4.18e-102 317.0 COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,1X3UR@135614|Xanthomonadales 135614|Xanthomonadales K accessory protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF k59_179228_1 1226994.AMZB01000109_gene1729 4.34e-176 502.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1YEZ0@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSbBS512_1146.SbBS512_E4187 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k59_364891_1 1207058.L53_02950 4.25e-49 171.0 COG2807@1|root,COG2807@2|Bacteria,1Q8U3@1224|Proteobacteria,2V7A4@28211|Alphaproteobacteria,43ZF9@69657|Hyphomonadaceae 28211|Alphaproteobacteria P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k59_468734_1 666685.R2APBS1_3353 4.65e-22 87.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1X70M@135614|Xanthomonadales 135614|Xanthomonadales K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 k59_468734_2 1163407.UU7_08218 2.14e-44 152.0 COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1X4B4@135614|Xanthomonadales 135614|Xanthomonadales M Lipoprotein - - - ko:K04754 - - - - ko00000 - - - MlaA k59_129606_1 1158292.JPOE01000002_gene2076 8.06e-79 245.0 COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2VJ31@28216|Betaproteobacteria,1KKBT@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH k59_1016865_1 1234364.AMSF01000033_gene322 1.34e-77 242.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1X38X@135614|Xanthomonadales 135614|Xanthomonadales S DinB superfamily - - - - - - - - - - - - DinB_2,FGE-sulfatase k59_1016865_2 1163409.UUA_01050 3.16e-58 190.0 COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,1X4P9@135614|Xanthomonadales 135614|Xanthomonadales S Methyltransferase - - - - - - - - - - - - Methyltransf_33 k59_179402_1 251229.Chro_0395 7.05e-182 532.0 COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,3VIE3@52604|Pleurocapsales 1117|Cyanobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase k59_1167107_1 745411.B3C1_01960 1.15e-118 354.0 COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,1RMG4@1236|Gammaproteobacteria,1J9XW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T 5TM C-terminal transporter carbon starvation CstA cstA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM k59_67479_1 1234364.AMSF01000063_gene2245 5.64e-157 460.0 COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,1X4B6@135614|Xanthomonadales 135614|Xanthomonadales O peptidase - - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N k59_1422325_1 553385.JEMF01000056_gene782 3.61e-22 94.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,1RQDY@1236|Gammaproteobacteria,1XI09@135619|Oceanospirillales 135619|Oceanospirillales S Cobalamin synthesis protein P47K - - - - - - - - - - - - CobW_C,cobW k59_1422325_2 1454202.PPBDW_120293___1 1.22e-56 176.0 COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,1S8S8@1236|Gammaproteobacteria,1XXYR@135623|Vibrionales 135623|Vibrionales O selenoprotein W-related protein - - - ko:K07401 - - - - ko00000 - - - Rdx k59_422257_1 95619.PM1_0224160 4.39e-36 129.0 COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3C9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S phosphoribosyl transferase - - - ko:K07100 - - - - ko00000 - - - Pribosyltran k59_1273768_1 2880.D7G3B8 8.18e-14 80.5 COG0358@1|root,2S0EV@2759|Eukaryota 2759|Eukaryota L DNA primase catalytic core, N-terminal domain - - - - - - - - - - - - DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 k59_187833_1 1229909.NSED_01320 1.84e-46 162.0 COG1009@1|root,arCOG01539@2157|Archaea,41TBF@651137|Thaumarchaeota 651137|Thaumarchaeota C Proton-conducting membrane transporter - - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k59_187833_2 436308.Nmar_0285 7.75e-38 140.0 COG1009@1|root,arCOG01539@2157|Archaea,41SC4@651137|Thaumarchaeota 651137|Thaumarchaeota C TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k59_1072641_1 666685.R2APBS1_3774 5.66e-24 99.4 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1X3WS@135614|Xanthomonadales 135614|Xanthomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N k59_1072641_2 1234364.AMSF01000030_gene3430 1.87e-49 160.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1X6GE@135614|Xanthomonadales 135614|Xanthomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N k59_1124143_1 1234364.AMSF01000015_gene3249 8e-39 143.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1X3FV@135614|Xanthomonadales 135614|Xanthomonadales M N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,LysM k59_1524407_1 380358.XALC_2226 3.67e-62 206.0 COG3669@1|root,COG3669@2|Bacteria,1R6V7@1224|Proteobacteria,1RWFD@1236|Gammaproteobacteria,1X3J1@135614|Xanthomonadales 135614|Xanthomonadales G alpha-l-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,F5_F8_type_C k59_1323329_1 420324.KI912082_gene6931 2.92e-107 313.0 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2TU4C@28211|Alphaproteobacteria,1JVU3@119045|Methylobacteriaceae 28211|Alphaproteobacteria Q Isochorismatase family - - - - - - - - - - - - Isochorismatase k59_625599_1 95619.PM1_0228310 4.04e-118 348.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k59_1273907_1 509190.Cseg_3138 1.78e-87 282.0 COG3669@1|root,COG3669@2|Bacteria,1R61E@1224|Proteobacteria,2TVR3@28211|Alphaproteobacteria,2KHS4@204458|Caulobacterales 204458|Caulobacterales G Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain - - 3.2.1.50 ko:K01205 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00078 R07816 - ko00000,ko00001,ko00002,ko01000,ko04147 - - - NAGLU,NAGLU_C,NAGLU_N k59_369048_1 1316936.K678_10485 5.64e-119 347.0 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2TRM0@28211|Alphaproteobacteria,2JQWS@204441|Rhodospirillales 204441|Rhodospirillales GM GDP-mannose 4,6 dehydratase - - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_1022891_1 666685.R2APBS1_2138 2.58e-88 273.0 COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,1RMJI@1236|Gammaproteobacteria,1X5JT@135614|Xanthomonadales 135614|Xanthomonadales EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr k59_138248_1 558884.JRGM01000135_gene1184 6.36e-41 147.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,1Y3NB@135624|Aeromonadales 135624|Aeromonadales M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N k59_722548_1 1415630.U771_20770 1.94e-27 112.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RQ6B@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU RND efflux system, outer membrane lipoprotein - - - - - - - - - - - - OEP k59_722548_2 1500890.JQNL01000001_gene1402 2.74e-38 141.0 COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1S3MR@1236|Gammaproteobacteria,1X5HW@135614|Xanthomonadales 135614|Xanthomonadales M Biotin-lipoyl like - - - - - - - - - - - - HlyD_D23 k59_24596_1 1120999.JONM01000003_gene2764 0.000112 46.2 COG3250@1|root,COG3250@2|Bacteria,1NKPN@1224|Proteobacteria,2VTD6@28216|Betaproteobacteria 28216|Betaproteobacteria G Immunoglobulin - - - - - - - - - - - - I-set k59_422483_1 658612.MD26_16410 1.01e-28 119.0 COG2132@1|root,COG2132@2|Bacteria,1N9H3@1224|Proteobacteria 1224|Proteobacteria Q Multicopper oxidase - - 1.16.3.3 ko:K22349 - - - - ko00000,ko01000 - - - - k59_970166_1 1234364.AMSF01000055_gene1090 1.44e-98 291.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,1X5YJ@135614|Xanthomonadales 135614|Xanthomonadales E COG2755 Lysophospholipase L1 and related esterases - - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL_2 k59_970166_2 396588.Tgr7_2115 1.87e-12 66.2 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1WW8Q@135613|Chromatiales 135613|Chromatiales Q ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k59_672886_1 436308.Nmar_0052 1.11e-87 262.0 COG0177@1|root,arCOG00459@2157|Archaea,41SFM@651137|Thaumarchaeota 651137|Thaumarchaeota L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD k59_572885_1 666685.R2APBS1_3930 2.33e-93 280.0 COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,1S6CY@1236|Gammaproteobacteria,1X3CM@135614|Xanthomonadales 135614|Xanthomonadales P ABC-type sugar transport systems, permease components lacF - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 k59_572936_1 261292.Nit79A3_1064 3.57e-71 220.0 COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,372XK@32003|Nitrosomonadales 28216|Betaproteobacteria U MotA TolQ ExbB proton channel exbB2 - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB k59_24705_1 1122604.JONR01000050_gene3142 7.07e-53 181.0 COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria,1RQX0@1236|Gammaproteobacteria,1X3KM@135614|Xanthomonadales 135614|Xanthomonadales V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k59_1474265_1 521719.ATXQ01000009_gene902 2.48e-17 81.6 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YE56@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT Type IV pili methyl-accepting chemotaxis transducer N-term pilJ - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ k59_1474265_2 1245471.PCA10_03440 5.32e-41 139.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,1YCQV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria NT Two component signalling adaptor domain pilI - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW k59_24730_1 269482.Bcep1808_4271 3.22e-88 271.0 COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2VKD6@28216|Betaproteobacteria,1K89Q@119060|Burkholderiaceae 28216|Betaproteobacteria L Pfam Transposase, Mutator - - - - - - - - - - - - Transposase_mut k59_24760_1 1234364.AMSF01000015_gene3161 1.02e-65 214.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1X3UC@135614|Xanthomonadales 135614|Xanthomonadales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k59_773105_1 745411.B3C1_11469 5.62e-132 386.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1J5IR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k59_422698_1 1523503.JPMY01000004_gene1600 2.43e-63 198.0 COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,1RQYG@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2819,iECIAI39_1322.ECIAI39_4161,iEcSMS35_1347.EcSMS35_3977,iUTI89_1310.UTI89_C4186 Pribosyltran k59_773182_1 1499686.BN1079_03324 3.1e-49 162.0 COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfE GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0031224,GO:0044425,GO:0044464,GO:0055114,GO:0071944 - ko:K03613 - - - - ko00000 - - - Rnf-Nqr k59_773182_2 1301098.PKB_1448 1.13e-41 142.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria 1236|Gammaproteobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD k59_188567_1 420324.KI911965_gene1316 1.02e-53 189.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S transport system fused permease components - - - - - - - - - - - - DUF3394,DctM k59_923497_1 1123487.KB892867_gene1046 1e-85 260.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,2KUG2@206389|Rhodocyclales 206389|Rhodocyclales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k59_1422940_1 554065.XP_005848299.1 9.71e-12 66.2 COG0071@1|root,KOG0710@2759|Eukaryota,37TQV@33090|Viridiplantae,34MSH@3041|Chlorophyta 3041|Chlorophyta O Belongs to the small heat shock protein (HSP20) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 k59_1422940_2 1320556.AVBP01000015_gene913 1.93e-07 50.8 COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2UCYK@28211|Alphaproteobacteria,43KDC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria T Universal stress protein - - - - - - - - - - - - Usp k59_1323838_1 911239.CF149_20838 4.14e-10 59.3 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) lpxL GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 ko:K02517,ko:K12974 ko00540,ko01100,map00540,map01100 M00060 R05146,R10906 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - iEC042_1314.EC042_2597,iSF_1195.SF1061,iS_1188.S1138,iYL1228.KPN_01068 Lip_A_acyltrans k59_1323838_2 1149133.ppKF707_1208 9.03e-48 165.0 COG1752@1|root,COG1752@2|Bacteria,1PDQ2@1224|Proteobacteria,1RMWI@1236|Gammaproteobacteria,1YCXW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin k59_1474452_1 1268068.PG5_65220 1.08e-114 337.0 COG5361@1|root,COG5361@2|Bacteria,1PF7H@1224|Proteobacteria,1RY0Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1214) - - - - - - - - - - - - DUF1214 k59_1073281_1 1122214.AQWH01000039_gene4777 9.7e-17 82.8 COG3181@1|root,COG3181@2|Bacteria,1NKWK@1224|Proteobacteria,2U3H5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC k59_188773_1 1234364.AMSF01000001_gene2367 6.59e-49 163.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1X38K@135614|Xanthomonadales 135614|Xanthomonadales J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD k59_188773_2 1234364.AMSF01000001_gene2366 7.56e-37 133.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1X2ZP@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA k59_923657_1 383407.XOC_0385 4.76e-55 182.0 COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,1RNE6@1236|Gammaproteobacteria,1X4CV@135614|Xanthomonadales 135614|Xanthomonadales S PrpF protein fldA - 5.3.2.8 ko:K16514 ko00362,ko01120,map00362,map01120 - R07839 RC02426 ko00000,ko00001,ko01000 - - - PrpF k59_923657_2 1144342.PMI40_00389 1.44e-14 73.2 COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,2VIM3@28216|Betaproteobacteria 28216|Betaproteobacteria S Pfam Amidohydrolase ligJ - 4.1.1.46,4.2.1.83 ko:K10220,ko:K14333 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R00821,R04478 RC00390,RC00498 ko00000,ko00001,ko01000 - - - Amidohydro_2 k59_1023473_1 1459636.NTE_01238 1.87e-06 46.6 COG1522@1|root,arCOG01117@2157|Archaea 1459636.NTE_01238|- K COG1522 Transcriptional regulators - - - - - - - - - - - - - k59_238674_1 1125863.JAFN01000001_gene10 1.35e-24 101.0 COG1732@1|root,COG1732@2|Bacteria,1Q5JK@1224|Proteobacteria,431D7@68525|delta/epsilon subdivisions,2WX5G@28221|Deltaproteobacteria 28221|Deltaproteobacteria M Substrate binding domain of ABC-type glycine betaine transport system - - - - - - - - - - - - OpuAC k59_476339_1 666685.R2APBS1_3771 1.5e-89 276.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1X2YF@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3 k59_476339_2 1163408.UU9_14515 7.59e-109 321.0 COG0251@1|root,COG0251@2|Bacteria,1NQGP@1224|Proteobacteria,1S2VU@1236|Gammaproteobacteria,1X33B@135614|Xanthomonadales 135614|Xanthomonadales J pteridine-dependent deoxygenase rapK - 4.1.3.40,4.1.3.45 ko:K18240 ko00130,ko00400,ko01100,ko01110,map00130,map00400,map01100,map01110 M00117 R01302,R10597 RC00491,RC02148,RC03212 ko00000,ko00001,ko00002,ko01000 - - - - k59_1324063_1 666685.R2APBS1_3546 1.69e-98 294.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1X2XQ@135614|Xanthomonadales 135614|Xanthomonadales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k59_238772_1 757424.Hsero_0763 2.49e-08 57.8 COG3501@1|root,COG4253@1|root,COG3501@2|Bacteria,COG4253@2|Bacteria,1MU7Q@1224|Proteobacteria,2VJSR@28216|Betaproteobacteria,476WC@75682|Oxalobacteraceae 28216|Betaproteobacteria S Phage late control gene D protein (GPD) - - - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - DUF2345,Phage_GPD,T6SS_Vgr k59_1274622_2 1234364.AMSF01000053_gene1331 3.62e-27 100.0 290RZ@1|root,2ZNE4@2|Bacteria,1P6TN@1224|Proteobacteria,1SVGT@1236|Gammaproteobacteria,1X8NF@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_1389519_1 666685.R2APBS1_0817 1.49e-58 196.0 COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,1X4WM@135614|Xanthomonadales 1236|Gammaproteobacteria V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k59_1125036_1 414684.RC1_3363 1.09e-94 301.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,2JQQN@204441|Rhodospirillales 204441|Rhodospirillales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k59_889126_1 1163409.UUA_09826 1.18e-80 265.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1X3YE@135614|Xanthomonadales 135614|Xanthomonadales D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k59_889126_2 1163408.UU9_05569 3.07e-14 73.2 COG3115@1|root,COG3115@2|Bacteria,1MVHR@1224|Proteobacteria,1RMDB@1236|Gammaproteobacteria,1X3YH@135614|Xanthomonadales 135614|Xanthomonadales D Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins zipA - - ko:K03528 - - - - ko00000,ko03036 - - - ZipA_C k59_523681_1 1234364.AMSF01000053_gene1322 6.78e-141 404.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,1X3WM@135614|Xanthomonadales 135614|Xanthomonadales J Methylates ribosomal protein L11 prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA k59_824650_1 1390370.O203_04840 2.22e-87 262.0 COG5628@1|root,COG5628@2|Bacteria,1RHTG@1224|Proteobacteria,1S75N@1236|Gammaproteobacteria,1YFTY@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k59_970968_2 767434.Fraau_2378 4.47e-18 82.8 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1X3SP@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k59_1589678_1 1163407.UU7_07721 1.14e-71 237.0 COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,1RMP8@1236|Gammaproteobacteria,1X5EV@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - - - - - - - - - - MMPL k59_1227436_1 62928.azo2994 1.55e-59 205.0 COG4773@1|root,COG4773@2|Bacteria,1MW5E@1224|Proteobacteria,2VHUH@28216|Betaproteobacteria,2KVYM@206389|Rhodocyclales 206389|Rhodocyclales P Outer membrane receptor - - - ko:K16088 - - - - ko00000,ko02000 1.B.14.1.10,1.B.14.1.3,1.B.14.1.8 - - Plug,TonB_dep_Rec k59_953981_1 1001585.MDS_4594 3.59e-70 217.0 COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,1RPXK@1236|Gammaproteobacteria,1YE9S@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria ET belongs to the bacterial solute-binding protein 3 family artJ - - ko:K02030,ko:K09996,ko:K10014,ko:K10022 ko02010,map02010 M00226,M00229,M00235,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.1,3.A.1.3.11,3.A.1.3.3 - - SBP_bac_3 k59_953981_2 521719.ATXQ01000003_gene2152 9.32e-31 114.0 COG4215@1|root,COG4215@2|Bacteria,1RB6C@1224|Proteobacteria,1SYKM@1236|Gammaproteobacteria,1YCVE@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P Binding-protein-dependent transport system inner membrane component artQ - - ko:K02029,ko:K09999 ko02010,map02010 M00229,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.3 - - BPD_transp_1 k59_206478_2 1163408.UU9_13693 2.55e-24 97.1 2ASNM@1|root,31I3E@2|Bacteria,1QFSK@1224|Proteobacteria,1TD2I@1236|Gammaproteobacteria,1X8ED@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_1557359_1 1229909.NSED_05590 3.55e-29 111.0 arCOG03622@1|root,arCOG03622@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_1557373_1 95619.PM1_0226620 1.87e-86 262.0 COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU twitching motility protein pilT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k59_1557373_2 322710.Avin_03080 9.95e-54 174.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1RNPM@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis yggS - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N k59_653495_1 1234364.AMSF01000016_gene1663 9.62e-66 203.0 COG1791@1|root,COG1791@2|Bacteria,1RCZD@1224|Proteobacteria,1S42U@1236|Gammaproteobacteria,1X43T@135614|Xanthomonadales 135614|Xanthomonadales S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway mtnD GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.13.11.53,1.13.11.54 ko:K08967 ko00270,ko01100,map00270,map01100 M00034 R07363,R07364 RC01866,RC02018,RC02118 ko00000,ko00001,ko00002,ko01000 - - - ARD k59_653495_2 1234364.AMSF01000016_gene1664 5.29e-33 119.0 COG4229@1|root,COG4229@2|Bacteria,1R3V9@1224|Proteobacteria,1RP5Y@1236|Gammaproteobacteria,1X4M6@135614|Xanthomonadales 135614|Xanthomonadales E Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) mtnC GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.77 ko:K09880 ko00270,ko01100,map00270,map01100 M00034 R07395 RC02779 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase k59_206552_1 745411.B3C1_11062 1.36e-154 445.0 COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria,1J4N5@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB k59_206633_1 1207076.ALAT01000190_gene2994 2.82e-68 214.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1Z15M@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria O COG3118 Thioredoxin domain-containing protein ybbN GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077 - ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - TPR_19,TPR_20,Thioredoxin k59_353691_1 186497.PF1739 1.87e-63 211.0 COG1653@1|root,arCOG00151@2157|Archaea,2Y0AI@28890|Euryarchaeota,243YU@183968|Thermococci 183968|Thermococci G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1 k59_753816_1 436308.Nmar_1628 6.59e-81 260.0 COG0640@1|root,COG1328@1|root,arCOG00734@2157|Archaea,arCOG04889@2157|Archaea,41SBG@651137|Thaumarchaeota 651137|Thaumarchaeota FK Anaerobic ribonucleoside-triphosphate reductase - - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,HTH_20,NRDD k59_503488_1 1437882.AZRU01000076_gene1150 6.26e-102 304.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1YDF5@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Bacterial extracellular solute-binding protein potF - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_8 k59_1357588_1 382245.ASA_4013 5.09e-24 92.8 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,1Y4IA@135624|Aeromonadales 135624|Aeromonadales K Belongs to the P(II) protein family - - - ko:K04752 - - - - ko00000 - - - P-II k59_1357588_2 382245.ASA_4014 3.38e-111 329.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1Y526@135624|Aeromonadales 135624|Aeromonadales P Ammonium Transporter Family - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp k59_206887_1 1163408.UU9_03168 1.1e-91 297.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1X5K7@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k59_1011684_1 530564.Psta_1519 2.88e-46 166.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2IY5P@203682|Planctomycetes 203682|Planctomycetes E Methionine synthase - - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k59_1011684_2 985867.AEWF01000003_gene808 1.11e-08 53.9 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2U97J@28211|Alphaproteobacteria,47FCR@766|Rickettsiales 766|Rickettsiales C Ferredoxin fdxB - - ko:K04755 - - - - ko00000 - - - Fer2 k59_411393_1 1215092.PA6_017_01340 4.67e-132 384.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1YFIM@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k59_1062010_1 863365.XHC_1134 1.15e-95 301.0 COG4772@1|root,COG4772@2|Bacteria,1QU2E@1224|Proteobacteria,1T1N4@1236|Gammaproteobacteria,1X55S@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_961897_2 1384056.N787_02700 1.1e-13 70.5 COG5001@1|root,COG5001@2|Bacteria,1PHN2@1224|Proteobacteria,1SX1R@1236|Gammaproteobacteria,1X5RZ@135614|Xanthomonadales 135614|Xanthomonadales T PAS fold - - - - - - - - - - - - GGDEF,PAS_3 k59_170342_1 666685.R2APBS1_3779 9.59e-45 146.0 COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,1X7KC@135614|Xanthomonadales 135614|Xanthomonadales C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C k59_170342_2 1163409.UUA_12418 5.72e-17 78.6 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1X4NB@135614|Xanthomonadales 135614|Xanthomonadales C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A k59_1413203_1 76869.PputGB1_5024 8.76e-63 194.0 COG1607@1|root,COG1607@2|Bacteria,1REI5@1224|Proteobacteria,1S4M2@1236|Gammaproteobacteria,1YY51@136845|Pseudomonas putida group 1236|Gammaproteobacteria I PFAM thioesterase superfamily HA62_15520 - - - - - - - - - - - 4HBT k59_1413203_2 1163407.UU7_06763 4.76e-15 70.5 2A4IZ@1|root,30T5J@2|Bacteria,1PCTS@1224|Proteobacteria,1SXY2@1236|Gammaproteobacteria,1X6ZR@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_1371380_1 330214.NIDE0004 1.01e-151 450.0 COG0188@1|root,COG0188@2|Bacteria,3J0EH@40117|Nitrospirae 40117|Nitrospirae L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV k59_1062038_1 1234364.AMSF01000080_gene3054 2.71e-128 392.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,1X5HN@135614|Xanthomonadales 135614|Xanthomonadales L COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_61367_1 1163407.UU7_00932 8.13e-214 592.0 COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1X32H@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the peptidase S33 family pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 k59_1571439_1 344747.PM8797T_15793 1.56e-16 72.0 2E4YG@1|root,314KJ@2|Bacteria,2J1BH@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF3309) - - - - - - - - - - - - DUF3309 k59_220605_1 87626.PTD2_15542 1.89e-34 136.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q1JG@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS_9,dCache_1 k59_761470_1 1294143.H681_07860 5.83e-144 426.0 COG2365@1|root,COG4625@1|root,COG2365@2|Bacteria,COG4625@2|Bacteria,1R6UG@1224|Proteobacteria 1224|Proteobacteria T Tyrosine phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Autotransporter,Y_phosphatase3 k59_870901_1 95619.PM1_0203425 5.27e-58 189.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the CarA family carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040 CPSase_sm_chain,GATase k59_1463224_1 163908.KB235896_gene3032 0.000879 43.1 COG2199@1|root,COG3706@2|Bacteria,1G2YJ@1117|Cyanobacteria,1HJR0@1161|Nostocales 1117|Cyanobacteria T TIGRFAM diguanylate cyclase (GGDEF) domain - - 2.7.7.65 ko:K02488 ko02020,ko04112,map02020,map04112 M00511 R08057 - ko00000,ko00001,ko00002,ko01000,ko02022 - - - GGDEF k59_511359_1 1163409.UUA_13660 1.03e-20 91.3 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1X436@135614|Xanthomonadales 135614|Xanthomonadales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2 k59_511359_2 666685.R2APBS1_2780 1.27e-78 243.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,1X35P@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the transferase hexapeptide repeat family dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,THDPS_N_2 k59_761531_1 745411.B3C1_15744 4.31e-79 241.0 COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,1S9UB@1236|Gammaproteobacteria,1JBKE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Outer membrane lipoprotein Slp family slp GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0019867,GO:0042802 - ko:K07285 - - - - ko00000 - - - Slp k59_220761_1 1267534.KB906754_gene2691 3.46e-14 80.9 COG1807@1|root,COG1807@2|Bacteria,3Y404@57723|Acidobacteria,2JHJ1@204432|Acidobacteriia 204432|Acidobacteriia M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k59_13109_2 225937.HP15_653 2.75e-52 171.0 COG3498@1|root,COG3498@2|Bacteria,1Q8HB@1224|Proteobacteria,1S72X@1236|Gammaproteobacteria 1236|Gammaproteobacteria S tail tube protein - - - ko:K06908 - - - - ko00000 - - - Phage_tube k59_13109_3 1123518.ARWI01000001_gene2284 4.34e-140 412.0 COG3497@1|root,COG3497@2|Bacteria,1MW1V@1224|Proteobacteria,1RNUT@1236|Gammaproteobacteria,4624X@72273|Thiotrichales 72273|Thiotrichales S Phage tail sheath C-terminal domain - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C k59_561487_1 859657.RPSI07_mp0667 1.13e-44 157.0 2C6DJ@1|root,32THJ@2|Bacteria,1N23R@1224|Proteobacteria,2W4N1@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_612787_1 1229909.NSED_08970 1.15e-91 282.0 arCOG08812@1|root,arCOG08812@2157|Archaea,41T50@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_761581_1 477228.YO5_10070 1.11e-60 196.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYGG@1236|Gammaproteobacteria,1Z4DI@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B k59_561603_1 1121935.AQXX01000128_gene1910 4.5e-64 206.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1XHD6@135619|Oceanospirillales 135619|Oceanospirillales K in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon cysB - - ko:K13634 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k59_812022_1 1488328.JMCL01000057_gene1162 8.99e-59 187.0 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,1RS6V@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q 4-Oxalocrotonate decarboxylase - - 4.1.1.77 ko:K01617 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R02602,R05374 RC00751,RC02672 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase k59_812022_2 1488328.JMCL01000057_gene1163 5.88e-43 149.0 COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,1RPPW@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds mhpE - 2.3.3.13,4.1.3.39 ko:K01649,ko:K01666 ko00290,ko00360,ko00362,ko00620,ko00621,ko00622,ko01100,ko01110,ko01120,ko01210,ko01220,ko01230,map00290,map00360,map00362,map00620,map00621,map00622,map01100,map01110,map01120,map01210,map01220,map01230 M00432,M00545,M00569 R00750,R01213 RC00004,RC00307,RC00371,RC00470,RC02754 br01601,br01602,ko00000,ko00001,ko00002,ko01000 - - - DmpG_comm,HMGL-like k59_911944_1 1218352.B597_019725 1.99e-87 259.0 COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,1S3Z2@1236|Gammaproteobacteria,1YZW7@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria I Cytosolic long-chain acyl-CoA thioester hydrolase family protein vdlD - - ko:K10806 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT k59_911944_2 743720.Psefu_0111 1.13e-34 123.0 2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,1SGKD@1236|Gammaproteobacteria,1YY8G@136845|Pseudomonas putida group 1236|Gammaproteobacteria S Protein of unknown function (DUF3301) - - - - - - - - - - - - DUF3301 k59_1572020_1 1175306.GWL_12720 1.12e-08 55.1 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,2VIYM@28216|Betaproteobacteria,4752H@75682|Oxalobacteraceae 28216|Betaproteobacteria E Asparaginase iaaA - 3.4.19.5,3.5.1.1 ko:K01424,ko:K13051 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000,ko01002 - - - Asparaginase_2 k59_1572020_2 1144319.PMI16_02449 2.52e-58 198.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,4724D@75682|Oxalobacteraceae 28216|Betaproteobacteria P Belongs to the ABC transporter superfamily gsiA - - ko:K02031,ko:K02032,ko:K13892 ko02010,ko02024,map02010,map02024 M00239,M00348 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.11 - - ABC_tran,oligo_HPY k59_121170_1 521719.ATXQ01000001_gene555 1.41e-15 75.1 COG1463@1|root,COG1463@2|Bacteria,1Q6ZU@1224|Proteobacteria,1S6SW@1236|Gammaproteobacteria,1YJA7@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria Q MlaD protein - - - ko:K06192 - - - - ko00000 - - - MlaD k59_121170_2 1453503.AU05_20400 1.97e-25 102.0 COG3009@1|root,COG3009@2|Bacteria,1NKFI@1224|Proteobacteria,1SE65@1236|Gammaproteobacteria,1YG6F@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S ABC-type transport auxiliary lipoprotein component - - - ko:K09857 - - - - ko00000 - - - ABC_trans_aux k59_271171_1 1229909.NSED_09510 1.88e-103 307.0 COG1041@1|root,arCOG00047@2157|Archaea 2157|Archaea L RNA methylase trmG10 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 ko:K07446 - - - - ko00000,ko01000,ko03016 - - - THUMP,UPF0020 k59_912038_1 1221522.B723_11915 1.78e-34 131.0 COG4191@1|root,COG4191@2|Bacteria,1R8JK@1224|Proteobacteria,1SC56@1236|Gammaproteobacteria,1YSYB@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA k59_1312100_1 335541.Swol_2546 1.18e-07 58.5 COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1V2NQ@1239|Firmicutes,24CX8@186801|Clostridia 186801|Clostridia T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_9,Response_reg k59_1213537_1 1229909.NSED_01250 1.54e-147 425.0 COG0470@1|root,arCOG00470@2157|Archaea,41S9F@651137|Thaumarchaeota 651137|Thaumarchaeota L ATPase family associated with various cellular activities (AAA) - - - ko:K04800 ko03030,map03030 - - - ko00000,ko00001,ko03032 - - - AAA k59_1213537_2 1229909.NSED_01255 1.36e-50 161.0 arCOG08784@1|root,arCOG08784@2157|Archaea,41SVZ@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_221312_1 156889.Mmc1_1094 2.74e-33 134.0 COG2931@1|root,COG5276@1|root,COG2931@2|Bacteria,COG5276@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - FG-GAP,HemolysinCabind k59_761867_1 745411.B3C1_08616 5.3e-109 323.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1J4KY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - iPC815.YPO2896,iYL1228.KPN_02862 Aminotran_5 k59_361756_1 1131451.O1K_20422 1.4e-43 142.0 COG2963@1|root,COG2963@2|Bacteria,1MZ5C@1224|Proteobacteria,1S9KN@1236|Gammaproteobacteria,1X8CF@135614|Xanthomonadales 135614|Xanthomonadales L Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 k59_361756_2 1094184.KWO_0122140 4.56e-186 519.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1X5HK@135614|Xanthomonadales 135614|Xanthomonadales L Transposase and inactivated derivatives - - - - - - - - - - - - HTH_21,rve k59_1312189_1 864051.BurJ1DRAFT_3977 2.53e-37 141.0 COG4191@1|root,COG4191@2|Bacteria,1R8JK@1224|Proteobacteria,2WEZZ@28216|Betaproteobacteria,1KNBN@119065|unclassified Burkholderiales 28216|Betaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA k59_411933_1 1163407.UU7_03062 7.89e-132 400.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1X4NM@135614|Xanthomonadales 135614|Xanthomonadales C E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k59_1213677_1 436308.Nmar_0006 9.64e-58 182.0 arCOG08807@1|root,arCOG08807@2157|Archaea,41SRC@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_1213677_2 436308.Nmar_0005 1.47e-28 108.0 COG2241@1|root,arCOG00650@2157|Archaea,41SGN@651137|Thaumarchaeota 651137|Thaumarchaeota H TIGRFAM precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit - - 2.1.1.289 ko:K03399 ko00860,ko01100,map00860,map01100 - R05813,R07775 RC00003,RC02052,RC02053 ko00000,ko00001,ko01000 - - - TP_methylase k59_1513641_1 1229909.NSED_09935 1.7e-72 222.0 COG5491@1|root,arCOG00452@2157|Archaea,41SJ3@651137|Thaumarchaeota 651137|Thaumarchaeota D conserved protein implicated in secretion - - - - - - - - - - - - - k59_1463777_1 436308.Nmar_1008 1.18e-89 283.0 COG0458@1|root,COG0624@1|root,arCOG01107@2157|Archaea,arCOG01596@2157|Archaea 2157|Archaea EF ATP-grasp domain cxp2 - 3.4.17.11,3.5.1.18,6.3.2.4 ko:K01295,ko:K01439,ko:K01921,ko:K16181 ko00300,ko00473,ko00550,ko01100,ko01120,ko01230,ko01502,map00300,map00473,map00550,map01100,map01120,map01230,map01502 M00016 R01150,R02734,R10011 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011 - - - ATP-grasp_3,CPSase_L_D2,Dala_Dala_lig_C,M20_dimer,Peptidase_M20 k59_412056_1 227377.CBU_1627 0.00013 48.9 COG1357@1|root,COG2948@1|root,COG1357@2|Bacteria,COG2948@2|Bacteria,1N3WV@1224|Proteobacteria,1S91W@1236|Gammaproteobacteria,1JCWA@118969|Legionellales 118969|Legionellales U Bacterial conjugation TrbI-like protein icmE - - ko:K12209 - - - - ko00000,ko02044 3.A.7.9.1 - - Pentapeptide_4,TrbI k59_1012375_1 66897.DJ64_28695 1.42e-83 266.0 COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria 201174|Actinobacteria G Glycoside hydrolase - - - - - - - - - - - - Glyco_hydro_15 k59_221674_1 1163409.UUA_13425 1.95e-60 198.0 COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,1RNZN@1236|Gammaproteobacteria,1X4ZA@135614|Xanthomonadales 135614|Xanthomonadales G Converts alpha-aldose to the beta-anomer galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim k59_762087_1 1323663.AROI01000004_gene2137 0.000872 40.8 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008219,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0012501,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016779,GO:0019200,GO:0033692,GO:0033785,GO:0033786,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0070566,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 ko:K03272,ko:K21344 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECH74115_1262.ECH74115_4363,iECSP_1301.ECSP_4025,iECs_1301.ECs3935,iPC815.YPO0654,iZ_1308.Z4405 CTP_transf_like,PfkB k59_762087_2 521719.ATXQ01000004_gene1768 1.19e-119 348.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RZ2G@1236|Gammaproteobacteria,1YKHJ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - 2.3.1.180 ko:K00648,ko:K22317 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iJN746.PP_4379 ACP_syn_III,ACP_syn_III_C k59_762089_2 977880.RALTA_B0207 1.23e-108 317.0 COG2057@1|root,COG2057@2|Bacteria,1MWW1@1224|Proteobacteria,2VIBE@28216|Betaproteobacteria,1K086@119060|Burkholderiaceae 28216|Betaproteobacteria I TIGRFAM 3-oxoacid CoA-transferase, B subunit pcaJ - 2.8.3.6 ko:K01032 ko00362,ko01100,ko01120,map00362,map01100,map01120 - R02990 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k59_962587_1 1163407.UU7_08803 9.17e-53 169.0 COG5400@1|root,COG5400@2|Bacteria,1P2T5@1224|Proteobacteria,1T0V8@1236|Gammaproteobacteria,1X7CP@135614|Xanthomonadales 135614|Xanthomonadales S conserved protein UCP033924 - - - - - - - - - - - - - k59_271874_1 1245471.PCA10_03350 5.09e-133 383.0 COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1YEDG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k59_271878_1 666685.R2APBS1_3501 2.59e-88 273.0 COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1RP5M@1236|Gammaproteobacteria,1X57H@135614|Xanthomonadales 135614|Xanthomonadales V Multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE k59_121867_1 666685.R2APBS1_3625 3.75e-93 293.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RZ70@1236|Gammaproteobacteria,1X4ZJ@135614|Xanthomonadales 135614|Xanthomonadales S protease with the C-terminal PDZ domain - - - - - - - - - - - - Peptidase_M61,TPR_3 k59_1262765_1 666685.R2APBS1_0309 5.53e-91 271.0 COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,1RY2V@1236|Gammaproteobacteria,1X307@135614|Xanthomonadales 135614|Xanthomonadales CP abc transporter atp-binding protein - - 3.6.3.7 ko:K09697 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.115 - - ABC_tran k59_1262765_2 1163408.UU9_09957 4.37e-07 51.2 COG1668@1|root,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,1RQT1@1236|Gammaproteobacteria,1X3GM@135614|Xanthomonadales 135614|Xanthomonadales CP permease natB - - ko:K09696 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko02000 3.A.1.115 - - ABC2_membrane_2,ABC2_membrane_3 k59_1214107_1 1229909.NSED_01645 4.41e-30 115.0 arCOG08033@1|root,arCOG08643@1|root,arCOG08033@2157|Archaea,arCOG08643@2157|Archaea,41T3A@651137|Thaumarchaeota 651137|Thaumarchaeota S peptidyl-tyrosine sulfation - - - - - - - - - - - - - k59_1214107_2 436308.Nmar_0341 1.59e-26 106.0 COG1104@1|root,arCOG00066@2157|Archaea,41SB1@651137|Thaumarchaeota 651137|Thaumarchaeota E Cysteine desulfurase - - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 k59_1372943_1 502347.ESCAB7627_1509 5.68e-90 295.0 28JY7@1|root,2Z9NI@2|Bacteria,1R6EC@1224|Proteobacteria,1S0IB@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_1056073_1 535289.Dtpsy_1327 3.1e-86 259.0 COG2227@1|root,COG2227@2|Bacteria,1NM0B@1224|Proteobacteria,2VY5J@28216|Betaproteobacteria 28216|Betaproteobacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - Methyltransf_25,PCMT k59_860686_1 666685.R2APBS1_0122 1.95e-21 94.4 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1N4G0@1224|Proteobacteria,1RRIM@1236|Gammaproteobacteria,1X37H@135614|Xanthomonadales 135614|Xanthomonadales EU peptidase - - - - - - - - - - - - DPPIV_N,PD40,Peptidase_S9 k59_860686_2 1163408.UU9_04754 5.77e-40 149.0 COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,1X478@135614|Xanthomonadales 135614|Xanthomonadales E Prolyl oligopeptidase - - 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N k59_905874_1 864702.OsccyDRAFT_2368 7.96e-34 127.0 COG1922@1|root,COG1922@2|Bacteria,1G2U3@1117|Cyanobacteria,1HF84@1150|Oscillatoriales 1117|Cyanobacteria M Glycosyl transferase WecB/TagA/CpsF family - - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB k59_606052_1 745411.B3C1_04875 4.38e-52 171.0 COG5662@1|root,COG5662@2|Bacteria,1QJEV@1224|Proteobacteria,1THE7@1236|Gammaproteobacteria,1JBNC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Protein of unknown function (DUF3379) - - - - - - - - - - - - DUF3379 k59_210451_2 365044.Pnap_0077 1.96e-19 88.2 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,4AJ83@80864|Comamonadaceae 28216|Betaproteobacteria NU twitching motility protein - - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k59_260539_1 1297863.APJF01000043_gene209 2.79e-88 265.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,3JZ81@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - HTH_21,rve,rve_3 k59_705810_1 225849.swp_1623 2.24e-11 67.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,2QAGR@267890|Shewanellaceae 1236|Gammaproteobacteria G hydrolase, family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14 k59_1106011_1 1515746.HR45_15720 7.43e-69 232.0 COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,1RNMS@1236|Gammaproteobacteria,2QEKD@267890|Shewanellaceae 1236|Gammaproteobacteria P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k59_956161_2 1163408.UU9_16031 7.85e-49 156.0 COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1SA6S@1236|Gammaproteobacteria,1X7W1@135614|Xanthomonadales 135614|Xanthomonadales L Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_Tnp_1 k59_956161_3 522373.Smlt2417 6.95e-78 241.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RR8F@1236|Gammaproteobacteria,1X4GJ@135614|Xanthomonadales 135614|Xanthomonadales L Transposase and inactivated derivatives - - - - - - - - - - - - HTH_21,rve,rve_3 k59_110510_1 1122201.AUAZ01000022_gene3082 7.03e-137 392.0 COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,1RR82@1236|Gammaproteobacteria,466BC@72275|Alteromonadaceae 1236|Gammaproteobacteria D The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein nifH - 1.18.6.1 ko:K02588 ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120 M00175 R05185,R05496 RC00002,RC01395,RC02891 ko00000,ko00001,ko00002,ko01000 - - - Fer4_NifH k59_1361310_1 1229909.NSED_09895 1.33e-129 377.0 COG1679@1|root,arCOG04278@2157|Archaea,41SBC@651137|Thaumarchaeota 651137|Thaumarchaeota S Protein of unknown function (DUF521) - - - ko:K09123 - - - - ko00000 - - - DUF521 k59_355690_1 1469245.JFBG01000059_gene2398 6.48e-42 145.0 COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1WY02@135613|Chromatiales 135613|Chromatiales L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N k59_355690_2 349106.PsycPRwf_0375 6.53e-18 82.4 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,3NJHP@468|Moraxellaceae 1236|Gammaproteobacteria S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 k59_1305851_1 1499686.BN1079_02810 3.04e-133 390.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Methylmalonate-semialdehyde dehydrogenase mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k59_1056275_1 436308.Nmar_1331 2.59e-91 273.0 COG1475@1|root,arCOG01875@2157|Archaea 2157|Archaea K PFAM ParB domain protein nuclease - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc k59_210807_1 1458697.W6E8I4_9CAUD 7.38e-69 227.0 4QFDB@10239|Viruses,4QVA2@35237|dsDNA viruses no RNA stage,4QTSF@28883|Caudovirales,4QN7V@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_705998_1 1163408.UU9_13453 2.36e-81 260.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,1X44R@135614|Xanthomonadales 135614|Xanthomonadales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_260930_1 1245471.PCA10_04440 6.33e-156 445.0 COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,1RRHH@1236|Gammaproteobacteria,1YDRB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Sarcosine oxidase soxB - 1.5.3.1 ko:K00303 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO k59_160819_1 439235.Dalk_0017 2.9e-87 284.0 COG0458@1|root,COG0458@2|Bacteria,1NPMZ@1224|Proteobacteria,42NF3@68525|delta/epsilon subdivisions,2WM4C@28221|Deltaproteobacteria,2MIQ1@213118|Desulfobacterales 28221|Deltaproteobacteria F ATP-grasp domain - - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_0661 CPSase_L_D2,CPSase_L_D3,MGS k59_160864_1 1245471.PCA10_45500 1.19e-67 222.0 COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria,1YFFN@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria N ABC-type uncharacterized transport system - - - - - - - - - - - - ABC_transp_aux k59_160864_2 95619.PM1_0217185 8.1e-12 63.5 COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria 1236|Gammaproteobacteria N ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3 k59_1407485_1 301.JNHE01000014_gene2904 3.32e-98 298.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1YE3F@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C k59_906210_1 1234364.AMSF01000033_gene343 1.34e-65 213.0 COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,1RPNR@1236|Gammaproteobacteria,1X404@135614|Xanthomonadales 135614|Xanthomonadales N Belongs to the bacterial flagellin family flgL - - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N k59_160929_1 1500893.JQNB01000001_gene1913 3.83e-37 125.0 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,1X7EC@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the bacterial ribosomal protein bL35 family rpmI - - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p k59_160929_2 767434.Fraau_2448 9.5e-56 175.0 COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,1X78R@135614|Xanthomonadales 135614|Xanthomonadales J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 k59_1156638_1 1215092.PA6_037_00170 9.23e-53 175.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1YD5N@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0421 Glycos_trans_3N,Glycos_transf_3 k59_1156638_2 399739.Pmen_3946 6.36e-49 160.0 COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1YEPV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria EH Peptidase C26 pabA GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_3095,iEC042_1314.EC042_3623,iECABU_c1320.ECABU_c37840,iECED1_1282.ECED1_4024,iECNA114_1301.ECNA114_3463,iECOK1_1307.ECOK1_3780,iECP_1309.ECP_3451,iECS88_1305.ECS88_3751,iECSF_1327.ECSF_3187,iLF82_1304.LF82_1586,iNRG857_1313.NRG857_16660,iUMN146_1321.UM146_16880,iUTI89_1310.UTI89_C3863,ic_1306.c4135 GATase k59_1156639_1 1163409.UUA_11468 2.84e-35 137.0 COG3637@1|root,COG3637@2|Bacteria,1PA8J@1224|Proteobacteria,1S0HC@1236|Gammaproteobacteria,1X9YB@135614|Xanthomonadales 135614|Xanthomonadales M Putative outer membrane beta-barrel porin, MtrB/PioB - - - - - - - - - - - - MtrB_PioB k59_1362000_1 330214.NIDE0719 1.34e-90 276.0 28IX1@1|root,2Z8V3@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2914) - - - - - - - - - - - - DUF2914 k59_55870_1 1459636.NTE_01328 1.79e-21 92.8 COG0778@1|root,arCOG00288@2157|Archaea,41T1J@651137|Thaumarchaeota 651137|Thaumarchaeota C PFAM Nitroreductase - - - - - - - - - - - - Nitroreductase k59_1206874_1 1229909.NSED_09180 1.46e-39 140.0 COG0006@1|root,arCOG01000@2157|Archaea,41T14@651137|Thaumarchaeota 651137|Thaumarchaeota E Belongs to the peptidase M24B family - - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 k59_1206874_2 1229909.NSED_09175 5.43e-56 180.0 arCOG10600@1|root,arCOG10600@2157|Archaea,41T8K@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_1562102_4 402626.Rpic_4546 1.74e-16 72.0 2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,2VVYY@28216|Betaproteobacteria,1KA3X@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF3309) - - - - - - - - - - - - DUF3309 k59_1562102_9 1401065.HMPREF2130_10980 1.22e-89 283.0 COG1783@1|root,COG1783@2|Bacteria,1R66A@1224|Proteobacteria,2W8DU@28216|Betaproteobacteria,3T87D@506|Alcaligenaceae 28216|Betaproteobacteria S Phage terminase large subunit - - - - - - - - - - - - Terminase_3 k59_261349_1 745411.B3C1_03135 7.35e-12 65.1 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPES@1236|Gammaproteobacteria,1J4RD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k59_706234_1 1007104.SUS17_1641 2.93e-46 168.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,2TS28@28211|Alphaproteobacteria,2JZVY@204457|Sphingomonadales 204457|Sphingomonadales G Belongs to the glycosyl hydrolase 3 family - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C k59_1256356_1 1448139.AI20_11585 2.96e-23 95.1 COG4067@1|root,COG4067@2|Bacteria,1N0VV@1224|Proteobacteria,1S5YG@1236|Gammaproteobacteria,1Y4IK@135624|Aeromonadales 135624|Aeromonadales O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k59_1256356_2 380703.AHA_1518 3.76e-57 186.0 COG0500@1|root,COG0500@2|Bacteria,1MVSK@1224|Proteobacteria,1RMQY@1236|Gammaproteobacteria,1Y3ED@135624|Aeromonadales 135624|Aeromonadales J Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs cmoB - - ko:K15257 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_9 k59_111400_1 1163408.UU9_05104 2.05e-36 130.0 COG0451@1|root,COG0451@2|Bacteria,1MWYB@1224|Proteobacteria,1RQ91@1236|Gammaproteobacteria,1X3XI@135614|Xanthomonadales 135614|Xanthomonadales GM NAD(P)H-binding - - - - - - - - - - - - Epimerase k59_261466_1 76869.PputGB1_4492 6.56e-70 222.0 COG3137@1|root,COG3137@2|Bacteria,1MXHS@1224|Proteobacteria,1RY9P@1236|Gammaproteobacteria,1YWW3@136845|Pseudomonas putida group 1236|Gammaproteobacteria M Protein of unknown function, DUF481 - - - - - - - - - - - - DUF481 k59_1562258_1 1234364.AMSF01000046_gene1996 2.13e-109 327.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria,1X4TK@135614|Xanthomonadales 135614|Xanthomonadales S 2-methylcitrate dehydratase prpD - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD k59_161362_1 436308.Nmar_0877 4.14e-27 100.0 COG0640@1|root,arCOG03067@2157|Archaea,41T4C@651137|Thaumarchaeota 651137|Thaumarchaeota K transcriptional regulators - - - - - - - - - - - - HTH_20 k59_161362_2 436308.Nmar_0876 3.64e-55 174.0 COG0640@1|root,arCOG03067@2157|Archaea,41T62@651137|Thaumarchaeota 651137|Thaumarchaeota K transcriptional regulators - - - - - - - - - - - - - k59_456639_1 861208.AGROH133_03319 3.09e-16 76.6 COG0492@1|root,COG0492@2|Bacteria,1MVWS@1224|Proteobacteria,2TU6F@28211|Alphaproteobacteria,4B934@82115|Rhizobiaceae 28211|Alphaproteobacteria O Thioredoxin reductase - - - - - - - - - - - - Pyr_redox_2 k59_456639_2 1197906.CAJQ02000026_gene3708 4.94e-09 56.6 COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,2TVRD@28211|Alphaproteobacteria,3K5Z9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C k59_261642_1 208439.AJAP_21490 1.09e-18 84.7 COG2755@1|root,COG2755@2|Bacteria,2GRDF@201174|Actinobacteria,4E2G5@85010|Pseudonocardiales 201174|Actinobacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2,Ricin_B_lectin k59_306529_1 1500890.JQNL01000001_gene205 1.67e-72 242.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,1X3CF@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor for ferrienterochelin and colicins - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k59_1407802_1 301.JNHE01000023_gene2573 1.73e-23 97.8 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria,1YECN@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Alanine dehydrogenase/PNT, C-terminal domain pntAA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k59_1562404_1 642227.HA49_21035 1.32e-21 93.2 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RNYS@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Choline dehydrogenase and related flavoproteins - - 1.1.99.3 ko:K06151 ko00030,ko01100,ko01120,map00030,map01100,map01120 - R01741 RC00084 ko00000,ko00001,ko01000 - - - GMC_oxred_C,GMC_oxred_N k59_1562404_2 1179778.PMM47T1_12768 4.73e-32 118.0 28MKC@1|root,2ZAWN@2|Bacteria,1R5HN@1224|Proteobacteria,1RSFK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Gluconate 2-dehydrogenase subunit 3 - - 1.1.99.3 ko:K06152 ko00030,ko01100,ko01120,map00030,map01100,map01120 - R01741 RC00084 ko00000,ko00001,ko01000 - - - Gluconate_2-dh3 k59_956727_1 84531.JMTZ01000051_gene921 2.53e-19 87.0 COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,1RNFH@1236|Gammaproteobacteria,1X3VA@135614|Xanthomonadales 135614|Xanthomonadales C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ k59_956727_2 1122603.ATVI01000005_gene2994 6.46e-38 141.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1X3JM@135614|Xanthomonadales 135614|Xanthomonadales C Molybdopterin oxidoreductase Fe4S4 domain - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k59_1256484_1 1234364.AMSF01000041_gene21 2.6e-105 324.0 COG0308@1|root,COG0308@2|Bacteria,1MUV3@1224|Proteobacteria,1RS0E@1236|Gammaproteobacteria,1X344@135614|Xanthomonadales 135614|Xanthomonadales E Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 k59_1457843_1 330214.NIDE1185 1.51e-96 310.0 COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3J17I@40117|Nitrospirae 40117|Nitrospirae I Phosphate acyltransferases - - 2.3.1.40,6.2.1.20,6.2.1.3 ko:K01897,ko:K05939 ko00061,ko00071,ko00564,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00564,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R01406,R04864 RC00004,RC00014,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,Acyltransferase k59_261802_1 1234364.AMSF01000016_gene1603 2.67e-161 456.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1X3NH@135614|Xanthomonadales 135614|Xanthomonadales U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 k59_306644_1 1395571.TMS3_0121740 8.46e-38 130.0 COG3318@1|root,COG3318@2|Bacteria,1NA8N@1224|Proteobacteria,1S8HQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the UPF0149 family - - - ko:K07039 - - - - ko00000 - - - UPF0149 k59_306644_2 1109445.AGSX01000131_gene2808 4.44e-39 144.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,1Z1UR@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L DNA helicase recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind k59_1362669_1 436308.Nmar_1320 4.08e-44 158.0 COG1205@1|root,arCOG00555@2157|Archaea,41SZS@651137|Thaumarchaeota 651137|Thaumarchaeota L DEAD DEAH box helicase - - - ko:K06877 - - - - ko00000 - - - DEAD,DUF1998,Helicase_C k59_1362669_2 436308.Nmar_1321 1.75e-28 110.0 COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota 651137|Thaumarchaeota I Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k59_111963_1 987059.RBXJA2T_09197 1.96e-87 266.0 COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,1KJGI@119065|unclassified Burkholderiales 28216|Betaproteobacteria C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 k59_956955_1 1068980.ARVW01000001_gene2968 1.38e-50 172.0 COG0458@1|root,COG0458@2|Bacteria 2|Bacteria F carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity cpsL - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_3,ATPgrasp_Ter k59_1362853_1 95619.PM1_0207790 1.31e-15 81.3 COG4655@1|root,COG4655@2|Bacteria,1R41B@1224|Proteobacteria,1S49Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad,Tad_C k59_756595_2 1448139.AI20_19555 6.01e-43 141.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1Y4NX@135624|Aeromonadales 135624|Aeromonadales K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 k59_212152_1 1163617.SCD_n01826 2.69e-116 344.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria 28216|Betaproteobacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 k59_1458039_1 159087.Daro_3280 1.73e-31 122.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,2KV11@206389|Rhodocyclales 206389|Rhodocyclales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k59_1458039_2 640081.Dsui_3326 3.22e-53 177.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,2KVVV@206389|Rhodocyclales 206389|Rhodocyclales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG k59_1006835_1 767434.Fraau_1092 3.6e-130 396.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1X4G8@135614|Xanthomonadales 135614|Xanthomonadales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k59_433825_1 1442599.JAAN01000032_gene1552 6.94e-69 209.0 COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,1X6K2@135614|Xanthomonadales 135614|Xanthomonadales J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 k59_433825_2 1163408.UU9_12772 9.39e-26 96.7 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1X7EI@135614|Xanthomonadales 135614|Xanthomonadales J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k59_534488_1 1234364.AMSF01000024_gene3771 6.76e-41 150.0 COG0308@1|root,COG0308@2|Bacteria,1MUV3@1224|Proteobacteria,1RS0E@1236|Gammaproteobacteria,1X34X@135614|Xanthomonadales 135614|Xanthomonadales E aminopeptidase n - - - - - - - - - - - - Big_4,Peptidase_M1 k59_534488_2 1234364.AMSF01000024_gene3772 3.43e-38 142.0 COG3537@1|root,COG3537@2|Bacteria,1MXCY@1224|Proteobacteria,1S0AN@1236|Gammaproteobacteria,1X3FY@135614|Xanthomonadales 135614|Xanthomonadales G Glycosyl hydrolase family 92 - - - - - - - - - - - - Glyco_hydro_92 k59_433888_1 479434.Sthe_0724 1.34e-20 94.0 COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,27XRJ@189775|Thermomicrobia 189775|Thermomicrobia S Belongs to the peptidase M50B family - - - - - - - - - - - - CBS,Peptidase_M50 k59_583985_1 745411.B3C1_05292 1.78e-89 290.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J9KM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V AcrB/AcrD/AcrF family mexB - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k59_734012_1 338963.Pcar_2356 3.55e-15 80.1 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,43T01@69541|Desulfuromonadales 28221|Deltaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k59_1085041_1 551789.ATVJ01000001_gene1477 3.48e-65 211.0 COG4188@1|root,COG4188@2|Bacteria,1R6B7@1224|Proteobacteria 1224|Proteobacteria S Platelet-activating factor acetylhydrolase, isoform II - - - - - - - - - - - - PAF-AH_p_II k59_338500_1 1163409.UUA_00510 1.01e-39 139.0 COG1247@1|root,COG1247@2|Bacteria,1NC5U@1224|Proteobacteria,1SWEE@1236|Gammaproteobacteria,1X7B9@135614|Xanthomonadales 135614|Xanthomonadales M COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k59_338584_1 1459636.NTE_01702 1.01e-63 205.0 COG0379@1|root,arCOG04459@2157|Archaea,41S6Y@651137|Thaumarchaeota 651137|Thaumarchaeota H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA k59_434277_1 1144342.PMI40_04209 2.98e-83 255.0 COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,474YU@75682|Oxalobacteraceae 28216|Betaproteobacteria T HD domain - - - ko:K07814 - - - - ko00000,ko02022 - - - HD,HD_5,Response_reg k59_934580_1 272560.BPSL0896 4.34e-117 346.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,2VHVD@28216|Betaproteobacteria,1K0EF@119060|Burkholderiaceae 28216|Betaproteobacteria C Isocitrate dehydrogenase icd GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh k59_36453_1 1448139.AI20_19510 3.38e-71 226.0 COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,1RMB3@1236|Gammaproteobacteria 1236|Gammaproteobacteria G transporter - - - ko:K07783 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.1.4.4,2.A.1.4.6 - - MFS_1 k59_1085662_1 95619.PM1_0229535 9.6e-36 122.0 COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,1SGV7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - Transgly_assoc k59_639338_1 338969.Rfer_0120 6.89e-55 189.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,4AA83@80864|Comamonadaceae 28216|Betaproteobacteria T Chemotaxis sensory transducer - - - ko:K03406,ko:K03776,ko:K05874 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,PAS_3 k59_734561_1 1229909.NSED_04595 5.17e-21 93.2 COG0498@1|root,arCOG01434@2157|Archaea,41S5N@651137|Thaumarchaeota 651137|Thaumarchaeota E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP k59_734561_2 436308.Nmar_0834 1.83e-22 90.9 arCOG10552@1|root,arCOG10552@2157|Archaea,41T8T@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_709126_1 1163409.UUA_12138 8.3e-36 134.0 COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria,1X2Z8@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - LAGLIDADG_3,Ribonuc_red_lgC k59_809153_1 1380600.AUYN01000001_gene2197 4.63e-19 83.2 2EPDH@1|root,33H03@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_1210365_1 472759.Nhal_3695 6.44e-118 348.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1WWH3@135613|Chromatiales 135613|Chromatiales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB k59_216692_1 1280944.HY17_09460 3.94e-29 114.0 COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,43XCC@69657|Hyphomonadaceae 28211|Alphaproteobacteria IQ short chain dehydrogenase reductase family - - 1.1.1.304,1.1.1.76 ko:K18009 ko00650,map00650 - R03707,R09078,R10505 RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short_C2 k59_1259301_1 1218075.BAYA01000015_gene4297 1.07e-16 79.7 COG1309@1|root,COG1309@2|Bacteria,1NC1C@1224|Proteobacteria,2VX8K@28216|Betaproteobacteria,1K3Y6@119060|Burkholderiaceae 28216|Betaproteobacteria K Domain of unknown function (DUF1956) - - - - - - - - - - - - DUF1956,TetR_N k59_658866_1 745411.B3C1_08591 1.13e-102 317.0 COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1J748@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Sulfatase mdoB - - - - - - - - - - - Sulfatase k59_1367643_1 1298867.AUES01000017_gene3998 1.17e-18 85.1 COG0683@1|root,COG0683@2|Bacteria,1N11P@1224|Proteobacteria,2TRQ4@28211|Alphaproteobacteria,3JVI6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Periplasmic binding protein - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k59_1367643_2 1100720.ALKN01000028_gene2453 7.87e-63 195.0 COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria 1224|Proteobacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 k59_1259393_1 1395571.TMS3_0116125 4.42e-111 348.0 COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k59_266800_1 477184.KYC_14462 4.53e-58 197.0 COG2199@1|root,COG3706@2|Bacteria,1MX83@1224|Proteobacteria,2VP2I@28216|Betaproteobacteria,3T1SE@506|Alcaligenaceae 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - GGDEF,dCache_1 k59_1059834_1 342949.PNA2_0789 1.49e-65 210.0 COG1703@1|root,arCOG01226@2157|Archaea,2XUHG@28890|Euryarchaeota,242YC@183968|Thermococci 183968|Thermococci E GTPase activity - - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK k59_1510760_1 330214.NIDE0603 1.68e-99 303.0 COG1008@1|root,COG1008@2|Bacteria,3J0EQ@40117|Nitrospirae 40117|Nitrospirae C Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M k59_309984_1 1234364.AMSF01000031_gene3356 4.24e-144 414.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1RKGT@1224|Proteobacteria,1S6ZQ@1236|Gammaproteobacteria,1X563@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the ompA family mopB - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,TSP_3 k59_310002_1 330214.NIDE0195 4.7e-113 329.0 COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae 2|Bacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - FGE-sulfatase k59_559270_1 301.JNHE01000003_gene1890 1.89e-97 306.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1YF92@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom k59_659107_1 1163409.UUA_08029 1.01e-82 275.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales 135614|Xanthomonadales T Chemotaxis protein histidine kinase and related kinases pilL - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k59_217128_1 666685.R2APBS1_0573 1.96e-117 342.0 COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1X399@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rmlA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase k59_1368081_1 322710.Avin_26430 4.05e-17 82.0 COG0614@1|root,COG0614@2|Bacteria,1PGUA@1224|Proteobacteria,1SZVG@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k59_1368081_2 198628.Dda3937_00199 1.36e-20 92.0 COG4773@1|root,COG4773@2|Bacteria,1NZCG@1224|Proteobacteria,1T1NA@1236|Gammaproteobacteria 1236|Gammaproteobacteria P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_167127_1 640081.Dsui_1451 1.09e-61 198.0 COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales 206389|Rhodocyclales T (FHA) domain - - - - - - - - - - - - FHA k59_1568150_1 745411.B3C1_03025 2.2e-91 276.0 COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,1J5UY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S hydrolase of the alpha beta-hydrolase fold yheT GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 - ko:K07019 - - - - ko00000 - - - Abhydrolase_1 k59_867633_1 153721.MYP_1918 1.13e-88 272.0 COG0683@1|root,COG0683@2|Bacteria,4NH9C@976|Bacteroidetes,47NPI@768503|Cytophagia 976|Bacteroidetes E Periplasmic binding protein domain - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k59_1210838_1 1226994.AMZB01000057_gene5005 1.01e-66 203.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1S617@1236|Gammaproteobacteria,1YG7U@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria G FKBP-type peptidyl-prolyl cis-trans isomerase fbp - 5.2.1.8 ko:K01802,ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,Rhodanese k59_267343_1 864073.HFRIS_018883 9.45e-10 65.9 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria 28216|Betaproteobacteria NT chemotaxis - - - - - - - - - - - - 4HB_MCP_1,HAMP,MCPsignal,PAS_3,sCache_2 k59_267368_1 748247.AZKH_p0637 8.41e-59 189.0 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,2VTM1@28216|Betaproteobacteria 28216|Betaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family - - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k59_267368_2 1234364.AMSF01000010_gene490 1.06e-34 122.0 COG4764@1|root,COG4764@2|Bacteria,1MVRK@1224|Proteobacteria,1RQ79@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - SLT k59_759599_1 1163407.UU7_09982 4.48e-75 249.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,1X38M@135614|Xanthomonadales 135614|Xanthomonadales G COG1472 Beta-glucosidase-related glycosidases celD - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Glyco_hydro_3,Glyco_hydro_3_C k59_1411180_1 1231190.NA8A_19685 1.73e-45 159.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria,43IDK@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Cytochrome c cycG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Cytochrom_C k59_217451_1 745411.B3C1_17662 2.5e-79 238.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1J68Q@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate tsaC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061710,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC k59_217451_2 745411.B3C1_17667 2.98e-24 98.2 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1J4VP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2436,iBWG_1329.BWG_2198,iECDH10B_1368.ECDH10B_2601,iECDH1ME8569_1439.ECDH1ME8569_2370,iETEC_1333.ETEC_2549,iEcDH1_1363.EcDH1_1225,iEcHS_1320.EcHS_A2573,iEcolC_1368.EcolC_1243,iJO1366.b2436,iJR904.b2436,iY75_1357.Y75_RS12760 Coprogen_oxidas k59_167384_1 1229909.NSED_02845 2.84e-64 206.0 COG0500@1|root,arCOG01631@2157|Archaea,41TBE@651137|Thaumarchaeota 2157|Archaea Q RNA methylase - - - - - - - - - - - - - k59_559583_1 290317.Cpha266_0874 0.000349 48.1 COG1233@1|root,COG1233@2|Bacteria,1FDM1@1090|Chlorobi 1090|Chlorobi Q FAD dependent oxidoreductase - - 5.2.1.13 ko:K09835 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R07512 RC01960 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase,NAD_binding_8 k59_267558_1 745411.B3C1_07304 2.56e-52 168.0 COG1047@1|root,COG1047@2|Bacteria,1RGXG@1224|Proteobacteria,1S6XS@1236|Gammaproteobacteria,1J661@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 slyD1 - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C k59_1210989_1 1163407.UU7_02122 5.9e-39 138.0 COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,1RQ3E@1236|Gammaproteobacteria,1X2XD@135614|Xanthomonadales 135614|Xanthomonadales P cation diffusion facilitator family transporter - - - - - - - - - - - - Cation_efflux,ZT_dimer k59_1210989_2 1307437.J139_10098 5.1e-20 83.6 COG0346@1|root,COG0346@2|Bacteria,1RGTU@1224|Proteobacteria,1S6TM@1236|Gammaproteobacteria,2Q2DV@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria E COG0346 Lactoylglutathione lyase and related lyases - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k59_1368470_1 436308.Nmar_1068 8.09e-07 48.9 arCOG11451@1|root,arCOG11451@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_1368470_2 1229909.NSED_06230 6.83e-26 97.1 arCOG08788@1|root,arCOG08788@2157|Archaea,41T6K@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_809796_1 1163407.UU7_16200 1.62e-11 60.5 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1X6DQ@135614|Xanthomonadales 135614|Xanthomonadales J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N k59_809796_2 1163408.UU9_16986 2.86e-67 207.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1X3HT@135614|Xanthomonadales 135614|Xanthomonadales J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 k59_610654_3 1121405.dsmv_2363 1.06e-15 76.6 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - LysM,PG_binding_1,Peptidase_M23,Pesticin,SBP_bac_3 k59_117684_1 1229909.NSED_06980 1.42e-13 70.1 COG0420@1|root,arCOG00397@2157|Archaea,41S68@651137|Thaumarchaeota 651137|Thaumarchaeota L Calcineurin-like phosphoesterase superfamily domain - - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos_2 k59_117684_2 436308.Nmar_1245 4.23e-84 268.0 COG0419@1|root,COG1122@1|root,arCOG00202@2157|Archaea,arCOG00368@2157|Archaea,41S9P@651137|Thaumarchaeota 651137|Thaumarchaeota LP AAA domain - - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_15 k59_509536_1 666685.R2APBS1_3022 9.97e-63 204.0 COG0628@1|root,COG0628@2|Bacteria,1NG06@1224|Proteobacteria,1TKE2@1236|Gammaproteobacteria,1X5G1@135614|Xanthomonadales 135614|Xanthomonadales S Transmembrane protein 43 - - - - - - - - - - - - TMEM43 k59_117711_1 301.JNHE01000013_gene2814 1.12e-85 255.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1YEK0@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco k59_1310004_1 587753.EY04_05345 2.47e-89 263.0 COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008270,GO:0008685,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016849,GO:0030145,GO:0042180,GO:0042181,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3360 YgbB k59_359831_1 1234364.AMSF01000024_gene3825 7.47e-20 93.2 COG1835@1|root,COG1835@2|Bacteria,1N4HC@1224|Proteobacteria,1S3S5@1236|Gammaproteobacteria,1X5FI@135614|Xanthomonadales 135614|Xanthomonadales I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 k59_809942_1 767434.Fraau_1093 7.57e-65 199.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1X6UQ@135614|Xanthomonadales 135614|Xanthomonadales J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k59_809942_2 1234364.AMSF01000037_gene90 1.88e-112 349.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1X4G8@135614|Xanthomonadales 135614|Xanthomonadales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k59_868211_1 1283300.ATXB01000002_gene2823 1.35e-67 218.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,1XE3C@135618|Methylococcales 135618|Methylococcales M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 k59_1260095_1 287.DR97_4812 4.28e-90 276.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1YEGI@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k59_1260095_2 205922.Pfl01_1888 1.95e-08 54.3 COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,1YMGJ@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria K Transcriptional regulator cmpR_1 - - - - - - - - - - - HTH_1,LysR_substrate k59_509692_1 330214.NIDE0411 6.4e-81 258.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria 2|Bacteria P sulfate adenylyltransferase (ATP) activity cysC - 2.7.1.25,2.7.7.4 ko:K00860,ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU,GTP_EFTU_D3 k59_117935_1 745411.B3C1_06002 5.42e-156 447.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1J5A3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_1211246_1 1229909.NSED_07730 4.15e-72 226.0 COG1697@1|root,arCOG04143@2157|Archaea,41SQF@651137|Thaumarchaeota 651137|Thaumarchaeota L Relaxes both positive and negative superturns and exhibits a strong decatenase activity top6A - 5.99.1.3 ko:K03166 - - - - ko00000,ko01000,ko03032 - - - TP6A_N k59_1211246_2 436308.Nmar_1406 7.75e-54 172.0 COG0071@1|root,arCOG01833@2157|Archaea 2157|Archaea O Belongs to the small heat shock protein (HSP20) family - - - - - - - - - - - - - k59_310674_1 1500893.JQNB01000001_gene2661 8.13e-102 318.0 COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,1T2I5@1236|Gammaproteobacteria,1X59N@135614|Xanthomonadales 135614|Xanthomonadales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_460822_1 666685.R2APBS1_1266 5.19e-96 308.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X34J@135614|Xanthomonadales 135614|Xanthomonadales V Efflux pump membrane transporter - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k59_1368955_1 745411.B3C1_05387 1.02e-70 220.0 COG1396@1|root,COG1396@2|Bacteria,1NUY5@1224|Proteobacteria,1SNHT@1236|Gammaproteobacteria 1236|Gammaproteobacteria K sequence-specific DNA binding - - - - - - - - - - - - - k59_460920_1 76114.ebA4892 4.37e-106 316.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHGM@28216|Betaproteobacteria,2KVQ7@206389|Rhodocyclales 206389|Rhodocyclales P Belongs to the ABC transporter superfamily - - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 k59_960611_1 745411.B3C1_09902 4.3e-119 342.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1J5R4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein k59_1480282_2 1234364.AMSF01000056_gene1126 8.5e-30 119.0 COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RU5N@1236|Gammaproteobacteria,1X5JM@135614|Xanthomonadales 135614|Xanthomonadales S Sulfotransferase domain - - - - - - - - - - - - Sulfotransfer_3,TPR_16,TPR_8 k59_832917_1 745411.B3C1_05787 6.26e-45 152.0 COG1349@1|root,COG1349@2|Bacteria,1MUJG@1224|Proteobacteria,1RNW4@1236|Gammaproteobacteria,1J8HM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K DeoR C terminal sensor domain glmR - - ko:K03477 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR k59_832917_2 745411.B3C1_05792 2.34e-18 83.6 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1J4PN@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_4420,iYL1228.KPN_04135 Hexapep,Hexapep_2,NTP_transf_3 k59_33511_1 1454004.AW11_02753 3.57e-87 268.0 COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2VKHP@28216|Betaproteobacteria,1KR7J@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria U ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 k59_731462_1 1211777.BN77_p10780 4.15e-67 212.0 COG0300@1|root,COG0300@2|Bacteria,1MWNZ@1224|Proteobacteria,2TTFS@28211|Alphaproteobacteria,4B9YJ@82115|Rhizobiaceae 28211|Alphaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short k59_581890_2 1317124.DW2_06593 2.73e-15 75.9 COG0697@1|root,COG0697@2|Bacteria,1MXR0@1224|Proteobacteria,2TR9E@28211|Alphaproteobacteria,2XN1K@285107|Thioclava 28211|Alphaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k59_1431939_1 1234364.AMSF01000016_gene1615 4.93e-29 114.0 COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1GS@1236|Gammaproteobacteria,1XDBH@135614|Xanthomonadales 135614|Xanthomonadales P Sodium/hydrogen exchanger family - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger k59_979675_1 1217720.ALOX01000004_gene4088 3.76e-07 50.8 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,2JQZ1@204441|Rhodospirillales 204441|Rhodospirillales G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH k59_979675_2 1379701.JPJC01000007_gene3489 3.71e-19 89.4 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VF7J@28211|Alphaproteobacteria,2KDXG@204457|Sphingomonadales 204457|Sphingomonadales KLT Protein tyrosine kinase - - - - - - - - - - - - HAMP,Pkinase k59_731793_1 283699.D172_1297 1.2e-07 54.3 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RSAR@1236|Gammaproteobacteria,2Q1YD@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF k59_1283338_1 1234364.AMSF01000056_gene1134 2.99e-118 349.0 COG0477@1|root,COG2814@2|Bacteria,1MWKH@1224|Proteobacteria,1RS23@1236|Gammaproteobacteria,1X5R5@135614|Xanthomonadales 135614|Xanthomonadales EGP Major facilitator superfamily - - - ko:K08178 - - - - ko00000,ko02000 2.A.1.12 - - MFS_1,Sugar_tr k59_1480612_1 223283.PSPTO_5472 7.49e-47 153.0 COG0776@1|root,COG0776@2|Bacteria,1N18A@1224|Proteobacteria,1SAIM@1236|Gammaproteobacteria,1ZAN1@136849|Pseudomonas syringae group 1236|Gammaproteobacteria L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hupA - - ko:K05787 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k59_1480612_2 1211112.ALJC01000091_gene1254 5.57e-35 125.0 COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway ubiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 ko:K03181 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R01302 RC00491,RC02148 ko00000,ko00001,ko00002,ko01000 - - iZ_1308.Z5638 Chor_lyase k59_782017_1 1453503.AU05_09250 3.76e-69 223.0 COG3203@1|root,COG3203@2|Bacteria,1MWEA@1224|Proteobacteria,1RXX8@1236|Gammaproteobacteria,1YDHK@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - - - - - - - - - - - k59_83119_2 1301098.PKB_5224 3.07e-37 130.0 COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria 1236|Gammaproteobacteria S hemolysin iii yqfA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII k59_1133865_1 1163408.UU9_10834 2.83e-96 290.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1X3JR@135614|Xanthomonadales 135614|Xanthomonadales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa,Complex1_49kDa k59_731868_1 436308.Nmar_1389 1.55e-45 153.0 COG0543@1|root,arCOG02199@2157|Archaea,41SY5@651137|Thaumarchaeota 651137|Thaumarchaeota H Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,NAD_binding_1 k59_731868_2 436308.Nmar_1388 3.65e-73 234.0 COG1032@1|root,arCOG01357@2157|Archaea,41SCX@651137|Thaumarchaeota 651137|Thaumarchaeota C Radical SAM - - - - - - - - - - - - Radical_SAM k59_375877_2 1500893.JQNB01000001_gene1117 7.86e-16 80.5 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,1X3CF@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor for ferrienterochelin and colicins - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k59_743250_1 1234364.AMSF01000055_gene1021 1.99e-53 182.0 COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,1RQD4@1236|Gammaproteobacteria,1X4B8@135614|Xanthomonadales 135614|Xanthomonadales I Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_5,Acyltransferase k59_743250_2 1234364.AMSF01000055_gene1022 5.85e-32 116.0 COG2095@1|root,COG2095@2|Bacteria,1N689@1224|Proteobacteria,1RPV0@1236|Gammaproteobacteria,1X4BK@135614|Xanthomonadales 135614|Xanthomonadales U UPF0056 membrane protein - - - - - - - - - - - - MarC k59_649644_1 857087.Metme_0801 3.79e-60 207.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1XDXD@135618|Methylococcales 135618|Methylococcales P TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter - - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 k59_594477_1 1163407.UU7_06153 3.69e-52 187.0 COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,1X5BV@135614|Xanthomonadales 135614|Xanthomonadales U Large exoproteins involved in heme utilization or adhesion - - - - - - - - - - - - Haemagg_act k59_793312_1 436308.Nmar_0040 1.68e-56 181.0 COG0603@1|root,arCOG00039@2157|Archaea,41SGR@651137|Thaumarchaeota 651137|Thaumarchaeota H Queuosine biosynthesis protein QueC - - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_793312_2 1229909.NSED_09820 2.74e-25 97.4 arCOG08816@1|root,arCOG08816@2157|Archaea,41TAW@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_349283_1 748247.AZKH_1493 8.5e-66 216.0 COG0459@1|root,COG0459@2|Bacteria,1NSE7@1224|Proteobacteria,2W1QE@28216|Betaproteobacteria,2KY4J@206389|Rhodocyclales 206389|Rhodocyclales O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k59_694799_1 322710.Avin_40420 4.97e-114 332.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria 1236|Gammaproteobacteria E serine acetyltransferase cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0840 Hexapep,SATase_N k59_594639_1 1380394.JADL01000002_gene1248 1.62e-38 135.0 2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2TSBD@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Nitrile hydratase nthA - 4.2.1.84 ko:K01721,ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R02828,R04020,R05379,R05596,R07780,R07854 RC00483,RC00792,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_alpha k59_1345358_1 305700.B447_11572 1.44e-30 120.0 COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,2KU8W@206389|Rhodocyclales 206389|Rhodocyclales P ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k59_1192925_1 436308.Nmar_0973 1.78e-08 60.5 arCOG08728@1|root,arCOG08728@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_500063_1 395493.BegalDRAFT_1815 1.52e-26 109.0 COG1123@1|root,COG4239@1|root,COG4172@2|Bacteria,COG4239@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,45ZN9@72273|Thiotrichales 72273|Thiotrichales P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k59_500063_2 1089552.KI911559_gene727 1.01e-40 145.0 COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,2TR1Y@28211|Alphaproteobacteria,2JPAS@204441|Rhodospirillales 204441|Rhodospirillales P transport system, permease component - - - ko:K13895 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1,OppC_N k59_1545482_1 1234364.AMSF01000025_gene3637 4.76e-52 170.0 COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1RU35@1236|Gammaproteobacteria,1X3JV@135614|Xanthomonadales 135614|Xanthomonadales KT Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain tcsR - - - - - - - - - - - GerE,Response_reg k59_1545482_2 1463857.JOFZ01000012_gene1871 1.65e-72 234.0 COG0531@1|root,COG0531@2|Bacteria,2GNUF@201174|Actinobacteria 201174|Actinobacteria E amino acid - - - - - - - - - - - - AA_permease,AA_permease_2 k59_1443572_1 666685.R2APBS1_2266 1.65e-56 195.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1X489@135614|Xanthomonadales 135614|Xanthomonadales O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k59_1296050_1 745411.B3C1_08896 3.73e-76 243.0 COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,1RVY5@1236|Gammaproteobacteria,1JAKQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k59_545092_1 1158292.JPOE01000002_gene1439 4.73e-83 272.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,1KJ1Z@119065|unclassified Burkholderiales 28216|Betaproteobacteria F Carbamoyl-phosphate synthetase ammonia chain carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k59_1296146_1 1229909.NSED_01270 3.32e-60 191.0 COG5016@1|root,arCOG02095@2157|Archaea,41SKA@651137|Thaumarchaeota 651137|Thaumarchaeota C Biotin-requiring enzyme - - - ko:K18605 ko00720,ko01120,map00720,map01120 - R00742,R01859 RC00040,RC00097,RC00367,RC00609 ko00000,ko00001 - - - Biotin_lipoyl k59_1296146_2 436308.Nmar_0275 2.52e-42 141.0 COG1225@1|root,arCOG00310@2157|Archaea,41SKG@651137|Thaumarchaeota 651137|Thaumarchaeota O Redoxin - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k59_1545627_1 1245471.PCA10_51980 1.79e-145 419.0 COG0560@1|root,COG3830@1|root,COG0560@2|Bacteria,COG3830@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,1YEA7@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria ET phosphoserine phosphatase serB GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046872,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - iE2348C_1286.E2348C_4686,iEC042_1314.EC042_4885,iECO26_1355.ECO26_5594,iECSF_1327.ECSF_4321,iECUMN_1333.ECUMN_5012,iETEC_1333.ETEC_4743,iPC815.YPO0442,iUMNK88_1353.UMNK88_5307 ACT_6,HAD,Hydrolase k59_1443906_1 1229909.NSED_08925 9.4e-118 354.0 arCOG08793@1|root,arCOG08812@1|root,arCOG08793@2157|Archaea,arCOG08812@2157|Archaea,41SXB@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_1496537_1 380358.XALC_2980 5.7e-118 359.0 COG1874@1|root,COG1874@2|Bacteria,1MUVR@1224|Proteobacteria,1RPW9@1236|Gammaproteobacteria 1236|Gammaproteobacteria G beta-galactosidase bglY - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M k59_1097810_1 685778.AORL01000021_gene290 8.99e-92 277.0 COG0346@1|root,COG0346@2|Bacteria,1N1QT@1224|Proteobacteria,2TU6X@28211|Alphaproteobacteria,2K2CR@204457|Sphingomonadales 204457|Sphingomonadales E lactoylglutathione lyase activity - - - - - - - - - - - - - k59_1296669_1 984262.SGRA_2780 2.04e-38 143.0 COG4249@1|root,COG4642@1|root,COG4249@2|Bacteria,COG4642@2|Bacteria,4NJPY@976|Bacteroidetes,1J19S@117747|Sphingobacteriia 976|Bacteroidetes S Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - - - - - - - - - - MORN,Peptidase_C14,Peptidase_M48 k59_46421_1 1234364.AMSF01000056_gene1160 8.69e-138 409.0 COG0745@1|root,COG2199@1|root,COG2200@1|root,COG0745@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1X47Y@135614|Xanthomonadales 135614|Xanthomonadales T COG2202 FOG PAS PAC domain - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9 k59_1296825_1 745411.B3C1_04940 1e-108 338.0 COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,1J4KX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the peptidase M16 family ptrA - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M k59_744342_1 105559.Nwat_2279 3.84e-106 335.0 COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1MVKX@1224|Proteobacteria,1RMSH@1236|Gammaproteobacteria,1WY9K@135613|Chromatiales 135613|Chromatiales G alpha amylase catalytic - - 3.2.1.1,5.4.99.16 ko:K05343 ko00500,ko01100,map00500,map01100 - R01557,R02108,R02112,R11262 RC01816 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C k59_1496824_1 1500890.JQNL01000001_gene1835 1.22e-26 110.0 COG1538@1|root,COG1538@2|Bacteria,1MUZZ@1224|Proteobacteria,1RQEP@1236|Gammaproteobacteria,1X57X@135614|Xanthomonadales 135614|Xanthomonadales MU efflux transporter outer membrane - - - - - - - - - - - - OEP k59_794105_1 1234364.AMSF01000037_gene229 6.84e-102 303.0 COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria,1X4UH@135614|Xanthomonadales 135614|Xanthomonadales S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 k59_1346217_1 666685.R2APBS1_2045 7.37e-45 158.0 COG0859@1|root,COG0859@2|Bacteria,1N2DA@1224|Proteobacteria,1SBNA@1236|Gammaproteobacteria,1X65K@135614|Xanthomonadales 135614|Xanthomonadales M PFAM Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 k59_545821_1 1269813.ATUL01000006_gene1823 2.91e-14 74.3 COG4220@1|root,COG4220@2|Bacteria,1N5UT@1224|Proteobacteria,1SEHT@1236|Gammaproteobacteria 1236|Gammaproteobacteria L to SP P31061 (percent identity 27 query alignment coverage 86.5 subject alignment coverage 88.4 - - - - - - - - - - - - Phage_Nu1 k59_545821_2 1540823.A0A088F812_9CAUD 7.79e-25 103.0 4QE70@10239|Viruses,4QSZC@28883|Caudovirales,4QMIW@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_545821_3 1541883.A0A088FQV3_9CAUD 2.41e-228 654.0 4QAXX@10239|Viruses,4QPTB@28883|Caudovirales,4QHV2@10662|Myoviridae 10662|Myoviridae S Phage terminase large subunit (GpA) - - - - - - - - - - - - - k59_794171_1 1163407.UU7_15135 7.23e-24 92.8 2ADSJ@1|root,313I4@2|Bacteria,1QD08@1224|Proteobacteria,1T8UT@1236|Gammaproteobacteria,1XB9N@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_794171_2 1163407.UU7_15145 1.66e-36 125.0 COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,1SCD4@1236|Gammaproteobacteria,1X8UE@135614|Xanthomonadales 135614|Xanthomonadales S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc k59_794231_1 1163409.UUA_08201 1.55e-30 114.0 2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SH0X@1236|Gammaproteobacteria,1X8E2@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF4124) - - - - - - - - - - - - DUF4124 k59_1098205_1 1163408.UU9_05029 6.78e-132 409.0 COG0745@1|root,COG0784@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria,1XDBG@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase - - - - - - - - - - - - CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg k59_794345_1 595460.RRSWK_02330 3.58e-29 120.0 COG0457@1|root,COG0457@2|Bacteria,2IWTH@203682|Planctomycetes 203682|Planctomycetes S Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - - - - - - - - - - Peptidase_MA_2,TPR_16,TPR_19 k59_444635_1 1392489.JPOL01000003_gene242 3.81e-115 349.0 COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1HZTD@117743|Flavobacteriia,2XJT9@283735|Leeuwenhoekiella 976|Bacteroidetes C Aconitase family (aconitate hydratase) - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k59_846292_1 1299327.I546_1964 8.34e-36 134.0 COG3666@1|root,COG3666@2|Bacteria,2IA0I@201174|Actinobacteria,23AZU@1762|Mycobacteriaceae 201174|Actinobacteria L Transposase domain (DUF772) - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k59_744738_1 436308.Nmar_0724 9.33e-72 221.0 arCOG05906@1|root,arCOG05906@2157|Archaea,41T21@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_390553_1 666685.R2APBS1_3957 5.63e-102 298.0 2EDE2@1|root,337AD@2|Bacteria,1NA2N@1224|Proteobacteria,1RXQK@1236|Gammaproteobacteria,1X4IA@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_1045757_1 1207076.ALAT01000175_gene2113 4.56e-63 204.0 COG0810@1|root,COG0810@2|Bacteria,1RKRA@1224|Proteobacteria,1S52T@1236|Gammaproteobacteria,1Z16G@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M TonB C terminal tolA - - ko:K03646 - - - - ko00000,ko02000 2.C.1.2 - - TonB_2 k59_1045757_2 322710.Avin_36640 2.79e-19 86.3 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria 1236|Gammaproteobacteria U involved in the tonB-independent uptake of proteins tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k59_47198_1 1123020.AUIE01000031_gene2780 6.11e-12 64.3 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,1RMZ6@1236|Gammaproteobacteria,1YEJC@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Peptidase family M48 Z012_09445 - - - - - - - - - - - Peptidase_M48 k59_47198_2 1207076.ALAT01000147_gene290 4.91e-70 212.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1Z1AS@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 k59_1346686_1 1163408.UU9_16426 4.73e-27 104.0 COG0705@1|root,COG0705@2|Bacteria,1RD88@1224|Proteobacteria,1S5NF@1236|Gammaproteobacteria,1X4YW@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - - - - - - - - - - Rhomboid k59_696319_1 1163409.UUA_11418 4.36e-130 374.0 COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria,1X3HX@135614|Xanthomonadales 135614|Xanthomonadales GM dehydratase - - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd k59_696406_1 95619.PM1_0215780 8.37e-70 221.0 COG3081@1|root,COG3081@2|Bacteria,1NXJU@1224|Proteobacteria,1RZB2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S nucleoid-associated protein - - - ko:K06899 - - - - ko00000,ko03036 - - - NA37 k59_444953_1 713586.KB900536_gene2500 1.53e-21 98.2 COG4123@1|root,COG4123@2|Bacteria,1N6QK@1224|Proteobacteria,1SKXT@1236|Gammaproteobacteria,1X0IT@135613|Chromatiales 135613|Chromatiales S Methyltransferase domain - - - - - - - - - - - - Methyltransf_23 k59_390949_1 1163398.AJJP01000155_gene2785 6.52e-58 197.0 COG0243@1|root,COG0243@2|Bacteria,1MU6B@1224|Proteobacteria,1RNXW@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family ydeP - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdopterin,Molydop_binding k59_596777_1 1149133.ppKF707_1306 1.54e-89 276.0 COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF k59_546603_1 1123487.KB892834_gene2786 5.77e-105 311.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria,2KUHG@206389|Rhodocyclales 206389|Rhodocyclales D Rod shape-determining protein MreB mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k59_1194300_1 314278.NB231_17233 6.61e-85 280.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1WXPZ@135613|Chromatiales 135613|Chromatiales L DEAD DEAH box - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,HTH_42,Helicase_C k59_1098729_1 558884.JRGM01000145_gene2068 3.93e-83 246.0 COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,1S6WS@1236|Gammaproteobacteria,1Y5T3@135624|Aeromonadales 135624|Aeromonadales O Belongs to the small heat shock protein (HSP20) family - - - ko:K04080 - - - - ko00000,ko03110 - - - HSP20 k59_546672_1 595536.ADVE02000001_gene2292 2.02e-51 177.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria,36XKU@31993|Methylocystaceae 28211|Alphaproteobacteria F Formate--tetrahydrofolate ligase fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS k59_1098766_1 745411.B3C1_02265 6.49e-102 305.0 COG2265@1|root,COG2265@2|Bacteria,1MY45@1224|Proteobacteria,1RN2B@1236|Gammaproteobacteria,1J4SP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) trmA GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.35 ko:K00557 - - - - ko00000,ko01000,ko03016 - - - tRNA_U5-meth_tr k59_391143_1 1118235.CAJH01000023_gene1559 1.3e-68 231.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X4QK@135614|Xanthomonadales 135614|Xanthomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07789 ko02020,map02020 M00648 - - ko00000,ko00001,ko00002,ko02000 2.A.6.2 - - ACR_tran k59_696788_1 436308.Nmar_1198 1.57e-124 366.0 COG0585@1|root,arCOG04252@2157|Archaea,41S7C@651137|Thaumarchaeota 651137|Thaumarchaeota J tRNA pseudouridine synthase - - 5.4.99.27 ko:K06176 - - - - ko00000,ko01000,ko03016 - - - TruD k59_445301_1 1196835.A458_19765 3.32e-36 126.0 COG1708@1|root,COG1708@2|Bacteria,1NZBG@1224|Proteobacteria,1SQBS@1236|Gammaproteobacteria,1Z2U8@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Uncharacterised protein family (UPF0158) - - - - - - - - - - - - UPF0158 k59_445301_2 1395571.TMS3_0105255 1.23e-29 108.0 COG4270@1|root,COG4270@2|Bacteria,1N2NG@1224|Proteobacteria,1SA7N@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane - - - - - - - - - - - - - k59_47821_1 93220.LV28_09825 5.2e-91 284.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,1K0AB@119060|Burkholderiaceae 28216|Betaproteobacteria J Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C k59_696963_1 1131266.ARWQ01000001_gene1257 2.72e-90 285.0 COG2511@1|root,arCOG01719@2157|Archaea,41S8Q@651137|Thaumarchaeota 651137|Thaumarchaeota J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate gatE - 6.3.5.7 ko:K03330 ko00970,ko01100,map00970,map01100 - R03905 RC00010 ko00000,ko00001,ko01000 - - - GAD,GatB_N,GatB_Yqey k59_1046462_1 864051.BurJ1DRAFT_3669 3.77e-121 353.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VKSV@28216|Betaproteobacteria,1KN7P@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC k59_799409_2 237609.PSAKL28_34160 2.98e-66 204.0 COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,1S99J@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE tusD GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - ko:K07235 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DrsE k59_799409_3 264730.PSPPH_3077 1.34e-07 51.6 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,1RRVZ@1236|Gammaproteobacteria,1Z67T@136849|Pseudomonas syringae group 1236|Gammaproteobacteria S Belongs to the BI1 family yccA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0019222,GO:0030162,GO:0031224,GO:0044425,GO:0044464,GO:0050789,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071944,GO:0080090 - ko:K19416 - M00742 - - ko00000,ko00002,ko02000 1.A.14.2.1 - - Bax1-I k59_949430_1 330214.NIDE2927 3.2e-52 182.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,3J0AI@40117|Nitrospirae 40117|Nitrospirae J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k59_396320_1 1441930.Z042_11075 1.13e-38 145.0 COG1472@1|root,COG1472@2|Bacteria,1N0Q4@1224|Proteobacteria,1RNK6@1236|Gammaproteobacteria,4012Y@613|Serratia 1236|Gammaproteobacteria G Glycosyl hydrolase family 3 N terminal domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Glyco_hydro_3,Glyco_hydro_3_C k59_1450115_1 1163407.UU7_16262 1.48e-30 119.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1X329@135614|Xanthomonadales 135614|Xanthomonadales NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k59_1450115_2 1234364.AMSF01000013_gene708 3.38e-30 119.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1X329@135614|Xanthomonadales 135614|Xanthomonadales NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k59_1450136_1 903818.KI912268_gene3429 2.61e-38 140.0 COG1475@1|root,COG1475@2|Bacteria,3Y7ZH@57723|Acidobacteria 57723|Acidobacteria K ParB-like nuclease domain - - - - - - - - - - - - ParBc k59_950138_1 644801.Psest_2393 3.46e-97 292.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1Z23G@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1540,iECS88_1305.ECS88_0472,iEcE24377_1341.EcE24377A_0515 Ferrochelatase k59_1450474_1 1234364.AMSF01000024_gene3851 1.21e-160 470.0 2CA5V@1|root,2Z9I7@2|Bacteria,1R50M@1224|Proteobacteria,1THFK@1236|Gammaproteobacteria,1X4JB@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_1450474_2 1234364.AMSF01000024_gene3850 3.33e-27 103.0 COG2823@1|root,COG2823@2|Bacteria,1PY9T@1224|Proteobacteria,1T6Y1@1236|Gammaproteobacteria,1X8DX@135614|Xanthomonadales 135614|Xanthomonadales S periplasmic or secreted lipoprotein - - - ko:K04065 - - - - ko00000 - - - BON k59_950314_1 1234364.AMSF01000072_gene1783 4.77e-129 381.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1X3E2@135614|Xanthomonadales 135614|Xanthomonadales S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 k59_800318_1 614083.AWQR01000005_gene924 1.05e-110 331.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,4AAKI@80864|Comamonadaceae 28216|Betaproteobacteria C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 k59_1199300_1 1031711.RSPO_c00465 2.16e-70 239.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VMEI@28216|Betaproteobacteria,1KH0V@119060|Burkholderiaceae 28216|Betaproteobacteria S alpha-2-macroglobulin domain protein 2 - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,Thiol-ester_cl k59_1199333_1 1163409.UUA_15693 2.23e-106 338.0 COG3537@1|root,COG3537@2|Bacteria,1N86N@1224|Proteobacteria,1RZCC@1236|Gammaproteobacteria,1X4Z0@135614|Xanthomonadales 135614|Xanthomonadales G Glycosyl hydrolase family 92 - - - - - - - - - - - - Glyco_hydro_92 k59_1450673_3 745411.B3C1_09218 1.46e-28 105.0 COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,1S9BC@1236|Gammaproteobacteria 1236|Gammaproteobacteria N flagellar protein FliS fliS - - ko:K02422 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliS k59_398700_1 1289387.AUKW01000009_gene4432 1.61e-98 302.0 COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria 201174|Actinobacteria I Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta accD1 - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans k59_398881_1 1245469.S58_30910 3.15e-24 106.0 COG0484@1|root,COG0484@2|Bacteria,1PJYM@1224|Proteobacteria,2VCNN@28211|Alphaproteobacteria,3K5RT@41294|Bradyrhizobiaceae 2|Bacteria C heat shock protein binding - - - - - - - - - - - - - k59_998399_1 1245471.PCA10_42430 2.62e-76 238.0 COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,1RQAG@1236|Gammaproteobacteria,1YCZG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein argR - - ko:K21825,ko:K21826 - - - - ko00000,ko03000 - - - DJ-1_PfpI,HTH_18 k59_998662_1 522373.Smlt2258 8.9e-07 53.9 COG0840@1|root,COG2770@1|root,COG0840@2|Bacteria,COG2770@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X3KX@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis protein - - - ko:K03406,ko:K05874 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,MCPsignal,sCache_2 k59_998662_2 1234364.AMSF01000086_gene2812 3.15e-105 312.0 COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1X5DZ@135614|Xanthomonadales 135614|Xanthomonadales NT Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP cheR2 - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N k59_999252_1 1234364.AMSF01000085_gene2888 1.23e-102 303.0 COG1633@1|root,COG1633@2|Bacteria,1R5XX@1224|Proteobacteria,1SNJ6@1236|Gammaproteobacteria,1X4FE@135614|Xanthomonadales 135614|Xanthomonadales S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - - - - - - - - - - - k59_1254140_2 477184.KYC_08840 3.42e-39 142.0 COG2199@1|root,COG3706@2|Bacteria,1PNTP@1224|Proteobacteria,2VPKG@28216|Betaproteobacteria,3T5XR@506|Alcaligenaceae 28216|Betaproteobacteria T COG2199 FOG GGDEF domain - - - - - - - - - - - - GGDEF k59_857417_2 1207063.P24_02026 1.9e-27 109.0 COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,2TUJR@28211|Alphaproteobacteria,2JRTP@204441|Rhodospirillales 204441|Rhodospirillales S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans k59_1154462_1 745411.B3C1_17752 5.36e-146 414.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1J5F1@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2564,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 PdxJ k59_454182_1 1006000.GKAS_03186 2.2e-196 555.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RY4Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD k59_1154479_1 1234364.AMSF01000088_gene2770 2.56e-97 296.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1X3DG@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the aldehyde dehydrogenase family aldA - - ko:K00138 ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120 - R00711 RC00047 ko00000,ko00001,ko01000 - - - Aldedh k59_1558031_2 1219375.CM002139_gene2826 7.96e-10 61.2 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,1X3CF@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor for ferrienterochelin and colicins - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k59_304139_1 562970.Btus_1769 8.94e-48 167.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 k59_1054452_1 1163407.UU7_10930 4.4e-98 298.0 COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,1RQG2@1236|Gammaproteobacteria,1X40V@135614|Xanthomonadales 135614|Xanthomonadales Q Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate hmgA - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA k59_53780_1 301.JNHE01000001_gene513 4.28e-96 291.0 COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,1RYFV@1236|Gammaproteobacteria,1YGP4@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - 4.2.1.156,4.2.1.42,5.1.2.2 ko:K01781,ko:K20023 ko00053,ko00627,ko01120,map00053,map00627,map01120 - R03791,R04161,R05608 RC00543,RC00998 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N k59_503749_1 388399.SSE37_09768 1.27e-17 80.1 COG0454@1|root,COG0456@2|Bacteria,1RBE6@1224|Proteobacteria,2U9H8@28211|Alphaproteobacteria 28211|Alphaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 k59_503749_2 376733.IT41_00205 0.000177 43.9 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TTYB@28211|Alphaproteobacteria,2PXJZ@265|Paracoccus 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k59_1558202_1 743720.Psefu_0660 7.71e-162 462.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1YV4S@136845|Pseudomonas putida group 1236|Gammaproteobacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k59_1558251_1 765912.Thimo_1012 3.14e-65 211.0 COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1WXZW@135613|Chromatiales 135613|Chromatiales L PFAM integrase - - - - - - - - - - - - HTH_21,rve k59_1558251_2 536019.Mesop_1196 1.22e-05 48.5 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,43H5V@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C aldo keto reductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 - - - - - - - - - - Aldo_ket_red k59_1455339_1 1045855.DSC_09900 1.84e-161 457.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,1RPKM@1236|Gammaproteobacteria,1X5DB@135614|Xanthomonadales 135614|Xanthomonadales G chitin deacetylase - - - - - - - - - - - - Polysacc_deac_1 k59_107502_1 1301098.PKB_5737 3.39e-149 429.0 COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RQ0P@1236|Gammaproteobacteria 1236|Gammaproteobacteria P rieske 2fe-2s gbcA - - ko:K00479 - - - - ko00000 - - - Rieske,Ring_hydroxyl_A k59_1204878_1 1163409.UUA_08039 1.94e-94 278.0 COG0835@1|root,COG0835@2|Bacteria,1RCIR@1224|Proteobacteria,1S61F@1236|Gammaproteobacteria,1X5IW@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis signal transduction protein pilI - - ko:K02659 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CheW k59_53997_1 1453503.AU05_24305 2.3e-71 226.0 COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,1RMBE@1236|Gammaproteobacteria,1YCY4@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Permease family purP - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease k59_53997_2 1226994.AMZB01000126_gene4060 4.91e-15 73.6 COG2813@1|root,COG2813@2|Bacteria,1NEMR@1224|Proteobacteria,1RMXE@1236|Gammaproteobacteria,1YD8G@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA rlmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172,2.1.1.174 ko:K00564,ko:K11391 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS k59_704428_1 1149133.ppKF707_2677 3.47e-105 314.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RZG1@1236|Gammaproteobacteria,1YJ82@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k59_1455500_2 1266925.JHVX01000009_gene130 7.82e-43 144.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria,3737P@32003|Nitrosomonadales 28216|Betaproteobacteria O PFAM Alkyl hydroperoxide reductase bcp GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA k59_754335_2 1229909.NSED_08995 3.17e-93 276.0 COG1394@1|root,arCOG04101@2157|Archaea,41T0N@651137|Thaumarchaeota 651137|Thaumarchaeota C Produces ATP from ADP in the presence of a proton gradient across the membrane atpD - - ko:K02120 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_D k59_1505517_1 1158292.JPOE01000005_gene429 2.45e-148 429.0 COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,1MVZ0@1224|Proteobacteria,2VKEY@28216|Betaproteobacteria,1KN85@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Nucleoside recognition spmAB - - - - - - - - - - - Gate k59_503962_1 292415.Tbd_1174 1.51e-57 202.0 COG1640@1|root,COG3280@1|root,COG1640@2|Bacteria,COG3280@2|Bacteria,1QTVJ@1224|Proteobacteria,2WGPV@28216|Betaproteobacteria 28216|Betaproteobacteria G 4-alpha-glucanotransferase treY - 2.4.1.25,5.4.99.15 ko:K00705,ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R05196,R09995 RC00049 ko00000,ko00001,ko00002,ko01000 - GH13,GH77 - Alpha-amylase,Glyco_hydro_77 k59_454575_1 930166.CD58_04155 2.14e-76 237.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the CarA family carA GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1950,iUTI89_1310.UTI89_C0036,ic_1306.c0040 CPSase_sm_chain,GATase k59_454575_2 95619.PM1_0203415 2.48e-48 171.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041 CPSase_L_D2,CPSase_L_D3,MGS k59_1204984_2 95619.PM1_0227930 2.71e-68 216.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Required for the activity of the bacterial periplasmic transport system of putrescine potF - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_8 k59_1358605_1 301.JNHE01000028_gene835 1.06e-121 351.0 COG4598@1|root,COG4598@2|Bacteria,1QTS2@1224|Proteobacteria,1RQYN@1236|Gammaproteobacteria,1YFCY@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E AAA domain, putative AbiEii toxin, Type IV TA system HA62_27665 - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k59_304483_1 1245471.PCA10_48550 3.16e-152 451.0 COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1YDYI@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria Q MlaD protein yebT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016020,GO:0016021,GO:0016043,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0071944,GO:0120009 - ko:K06192 - - - - ko00000 - - - MlaD k59_354334_1 1120950.KB892731_gene3787 2.68e-46 158.0 COG4122@1|root,COG4122@2|Bacteria,2IARG@201174|Actinobacteria,4DST0@85009|Propionibacteriales 201174|Actinobacteria S Macrocin-O-methyltransferase (TylF) - - - ko:K05303 - - - - ko00000,ko01000 - - - TylF k59_354334_2 640081.Dsui_2039 2.52e-09 57.0 COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VHYA@28216|Betaproteobacteria,2KV3P@206389|Rhodocyclales 206389|Rhodocyclales E Cys/Met metabolism PLP-dependent enzyme - - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP k59_804506_1 1124983.PFLCHA0_c59180 6e-148 431.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,1YMR4@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria P Iron ABC transporter fbpB - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k59_257978_1 1448139.AI20_19685 6.58e-114 341.0 COG3275@1|root,COG3275@2|Bacteria,1QUB1@1224|Proteobacteria,1T1RX@1236|Gammaproteobacteria,1Y4YZ@135624|Aeromonadales 135624|Aeromonadales T Histidine kinase - - 2.7.13.3 ko:K02478 - - - - ko00000,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,His_kinase k59_858285_1 398578.Daci_1943 6.79e-54 189.0 COG3064@1|root,COG3064@2|Bacteria,1R6JV@1224|Proteobacteria 1224|Proteobacteria M Membrane - - - - - - - - - - - - - k59_257998_2 1163409.UUA_01045 1.14e-31 121.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1X38X@135614|Xanthomonadales 135614|Xanthomonadales S DinB superfamily - - - - - - - - - - - - DinB_2,FGE-sulfatase k59_1358716_1 1163409.UUA_04813 1.86e-100 306.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1X4G4@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k59_1358716_2 160492.XF_1289 1.06e-36 131.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1X45V@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 k59_1254629_1 745411.B3C1_06333 1.51e-62 212.0 COG5001@1|root,COG5001@2|Bacteria,1PSFV@1224|Proteobacteria,1RY72@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF k59_108047_1 745411.B3C1_08196 3.09e-93 291.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RR88@1236|Gammaproteobacteria,1J5WK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EU COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - - - - - - - - - - PD40,Peptidase_S9 k59_1155018_1 1301098.PKB_0390 1.37e-52 179.0 COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Peptidase, M16 - - 2.7.7.6 ko:K00960,ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k59_1155018_2 95619.PM1_0226760 2.72e-20 86.3 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle rsmD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 k59_1004818_1 436308.Nmar_1103 6.82e-123 365.0 COG0322@1|root,arCOG04753@2157|Archaea,41SX9@651137|Thaumarchaeota 651137|Thaumarchaeota L TIGRFAM excinuclease ABC, C subunit - - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,UVR,UvrC_HhH_N k59_1358936_1 1163408.UU9_01469 1.15e-135 390.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1X3PJ@135614|Xanthomonadales 135614|Xanthomonadales J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k59_108194_1 360094.PXO_04700 1.29e-56 198.0 COG3501@1|root,COG4253@1|root,COG3501@2|Bacteria,COG4253@2|Bacteria,1MU7Q@1224|Proteobacteria,1RN6G@1236|Gammaproteobacteria,1XCAW@135614|Xanthomonadales 135614|Xanthomonadales S Type IV secretion protein Rhs - - - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - DUF2345,Phage_GPD,T6SS_Vgr k59_1559125_1 301.JNHE01000026_gene3098 1.55e-128 382.0 COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,1RNFJ@1236|Gammaproteobacteria,1YE8N@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T PrkA AAA domain yeaG GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA k59_5501_1 1163398.AJJP01000057_gene2030 1.83e-30 126.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria 1236|Gammaproteobacteria M mechanosensitive ion channel kefA GO:0005575,GO:0005623,GO:0005886,GO:0006884,GO:0008150,GO:0008361,GO:0009987,GO:0009992,GO:0016020,GO:0016043,GO:0019725,GO:0030104,GO:0032535,GO:0042592,GO:0044464,GO:0048878,GO:0055082,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - ko:K05802,ko:K22051 - - - - ko00000,ko02000 1.A.23.1.1,1.A.23.1.2,1.A.23.1.3 - - MS_channel,MscS_TM,MscS_porin k59_208391_1 666685.R2APBS1_1233 7.61e-62 205.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,1RME9@1236|Gammaproteobacteria,1X3K4@135614|Xanthomonadales 135614|Xanthomonadales P Ferrous iron transport protein B feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate k59_208391_2 1234364.AMSF01000056_gene1238 1.74e-30 108.0 COG1918@1|root,COG1918@2|Bacteria,1NASN@1224|Proteobacteria,1T0T4@1236|Gammaproteobacteria,1XD1N@135614|Xanthomonadales 135614|Xanthomonadales P Fe2 transport system protein A feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA k59_1304765_1 287.DR97_2667 1.54e-139 412.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1YDE4@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_1559292_1 1500890.JQNL01000001_gene3520 1.39e-61 213.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,1X3CF@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor for ferrienterochelin and colicins - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k59_1406007_1 1234364.AMSF01000085_gene2915 8.17e-93 279.0 COG1307@1|root,COG1307@2|Bacteria,1R5M9@1224|Proteobacteria,1S6F7@1236|Gammaproteobacteria,1X49M@135614|Xanthomonadales 135614|Xanthomonadales S lipid binding - - - - - - - - - - - - DegV k59_1105021_1 1205753.A989_17078 1.61e-19 89.4 COG3250@1|root,COG3250@2|Bacteria,1NYBH@1224|Proteobacteria,1RZPC@1236|Gammaproteobacteria,1XCMD@135614|Xanthomonadales 135614|Xanthomonadales G Glycosyl hydrolases family 2 - - 3.2.1.25 ko:K01192 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000 - - - Glyco_hydro_2,Glyco_hydro_2_C k59_1105021_2 1500893.JQNB01000001_gene1943 1.52e-20 95.9 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1X3B5@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_354654_1 1208321.D104_11805 7.58e-98 303.0 COG0754@1|root,COG3942@1|root,COG0754@2|Bacteria,COG3942@2|Bacteria,1MW6V@1224|Proteobacteria,1RQAP@1236|Gammaproteobacteria,1XHKB@135619|Oceanospirillales 135619|Oceanospirillales E Glutathionylspermidine synthase - - 3.5.1.78,6.3.1.8 ko:K01460 ko00480,ko01100,map00480,map01100 - R01917,R01918 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CHAP,GSP_synth k59_969574_1 95619.PM1_0225595 1.11e-27 110.0 COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,1RMJT@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation sthA GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019725,GO:0022857,GO:0022890,GO:0034220,GO:0036094,GO:0042592,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0065007,GO:0065008,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363,GO:1902600 1.6.1.1 ko:K00322 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - iECED1_1282.ECED1_4669,iECs_1301.ECs4891,iZ_1308.Z5521 Pyr_redox_2,Pyr_redox_dim k59_969574_2 521719.ATXQ01000003_gene2199 3.5e-13 68.2 COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1YE0F@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD k59_1172261_1 1304275.C41B8_13940 1.6e-96 288.0 COG1175@1|root,COG1175@2|Bacteria,1MVF1@1224|Proteobacteria,1RRHX@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC transporter (permease) mtlF - - ko:K02025,ko:K05814,ko:K10228 ko02010,map02010 M00198,M00200,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3,3.A.1.1.5 - - BPD_transp_1 k59_625025_1 538979.C4ML56_9CAUD 1.79e-30 116.0 4QAIU@10239|Viruses,4QUQC@35237|dsDNA viruses no RNA stage,4QPDE@28883|Caudovirales,4QKM7@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - k59_922497_2 269799.Gmet_1645 0.000166 46.6 COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2WIRS@28221|Deltaproteobacteria,43TJ0@69541|Desulfuromonadales 28221|Deltaproteobacteria F Amidohydrolase family - - 3.5.4.40 ko:K20810 ko00130,ko01110,map00130,map01110 - R10695 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 k59_237179_1 745411.B3C1_09817 5.27e-26 102.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,1J62X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon gluQ GO:0000166,GO:0002097,GO:0003674,GO:0005488,GO:0005524,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c k59_237179_2 745411.B3C1_09812 4.36e-93 273.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1J63Q@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression dksA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k59_522369_1 1166130.H650_11780 3.29e-14 79.7 COG5283@1|root,COG5283@2|Bacteria,1NFKU@1224|Proteobacteria,1RP2D@1236|Gammaproteobacteria,3X1HM@547|Enterobacter 1236|Gammaproteobacteria S phage tail tape measure protein - - - - - - - - - - - - PhageMin_Tail k59_522369_2 1470593.BW43_03671 3.37e-15 76.3 COG3499@1|root,COG3499@2|Bacteria,1N88T@1224|Proteobacteria,1SB6U@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phage P2 GpU - - - ko:K06906 - - - - ko00000 - - - Phage_P2_GpU k59_137613_1 1234364.AMSF01000085_gene2903 3.25e-113 334.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1X32P@135614|Xanthomonadales 135614|Xanthomonadales E aminotransferase - - 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k59_823348_1 436308.Nmar_0059 2.08e-36 129.0 COG2875@1|root,arCOG00645@2157|Archaea,41SE7@651137|Thaumarchaeota 651137|Thaumarchaeota H Tetrapyrrole (Corrin/Porphyrin) Methylases - - 2.1.1.133,2.1.1.271 ko:K05936 ko00860,ko01100,map00860,map01100 - R05181,R05810 RC00003,RC01294,RC02049 ko00000,ko00001,ko01000 - - - TP_methylase k59_823348_2 436308.Nmar_0058 1.13e-74 229.0 COG2243@1|root,arCOG00648@2157|Archaea,41SGJ@651137|Thaumarchaeota 651137|Thaumarchaeota H Tetrapyrrole (Corrin/Porphyrin) Methylases - - 2.1.1.130,2.1.1.151 ko:K03394 ko00860,ko01100,map00860,map01100 - R03948,R05808 RC00003,RC01035,RC01662 ko00000,ko00001,ko01000 - - - TP_methylase k59_368767_1 1165096.ARWF01000001_gene352 1.06e-83 262.0 COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,2VNEJ@28216|Betaproteobacteria,2KKQV@206350|Nitrosomonadales 206350|Nitrosomonadales S Domain of unknown function (DUF4139) - - - - - - - - - - - - DUF4139 k59_969742_1 1229909.NSED_09660 1.43e-97 288.0 COG2241@1|root,arCOG00650@2157|Archaea,41SGN@651137|Thaumarchaeota 651137|Thaumarchaeota H TIGRFAM precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit - - 2.1.1.289 ko:K03399 ko00860,ko01100,map00860,map01100 - R05813,R07775 RC00003,RC02052,RC02053 ko00000,ko00001,ko01000 - - - TP_methylase k59_422099_1 1234364.AMSF01000088_gene2774 3.75e-146 435.0 COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,1RQYX@1236|Gammaproteobacteria,1X469@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor proteins mostly Fe transport yncD - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_1273593_1 342113.DM82_888 1.5e-71 239.0 COG2268@1|root,COG2268@2|Bacteria,1R8J0@1224|Proteobacteria,2VPBR@28216|Betaproteobacteria,1KIMY@119060|Burkholderiaceae 28216|Betaproteobacteria S Band 7 protein - - - - - - - - - - - - - k59_722194_2 1163408.UU9_01289 9.76e-20 86.7 COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1X5HS@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - ko:K09973 - - - - ko00000 - - - TraB k59_1473996_1 322710.Avin_47440 1.76e-147 436.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - iJN746.PP_5217 PP_kinase,PP_kinase_C,PP_kinase_N k59_1388327_1 1219035.NT2_02_05640 3.61e-52 176.0 COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,2K5UJ@204457|Sphingomonadales 204457|Sphingomonadales IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 k59_237595_1 1175306.GWL_32600 2.1e-110 327.0 COG3970@1|root,COG3970@2|Bacteria,1MVA2@1224|Proteobacteria,2VIXV@28216|Betaproteobacteria,4737B@75682|Oxalobacteraceae 28216|Betaproteobacteria S fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase k59_475381_1 794846.AJQU01000045_gene4412 4.28e-107 315.0 COG0395@1|root,COG0395@2|Bacteria,1MUT9@1224|Proteobacteria,2TRQ0@28211|Alphaproteobacteria,4BAS4@82115|Rhizobiaceae 28211|Alphaproteobacteria G Binding-protein-dependent transport system inner membrane component MA20_37640 - - ko:K17317 ko02010,map02010 M00605 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.24,3.A.1.1.30 - - BPD_transp_1 k59_34139_1 1448139.AI20_02015 1.59e-183 529.0 COG4412@1|root,COG4412@2|Bacteria,1P5IH@1224|Proteobacteria,1RPYC@1236|Gammaproteobacteria 1236|Gammaproteobacteria O peptidase M6 immune inhibitor A - - - ko:K09607 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M6 k59_582157_1 1453503.AU05_00725 3.14e-59 194.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,1RZG1@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP k59_1432265_1 1234364.AMSF01000016_gene1736 5.11e-55 177.0 COG4760@1|root,COG4760@2|Bacteria,1RDFF@1224|Proteobacteria,1S8H2@1236|Gammaproteobacteria,1XD48@135614|Xanthomonadales 135614|Xanthomonadales S Bax inhibitor 1 like - - - - - - - - - - - - BaxI_1 k59_1432265_2 381666.H16_B0303 3.81e-10 59.7 COG0697@1|root,COG0697@2|Bacteria,1PIE1@1224|Proteobacteria,2VHHE@28216|Betaproteobacteria,1K3XG@119060|Burkholderiaceae 28216|Betaproteobacteria EG of the drug metabolite transporter (DMT) superfamily yddG - - - - - - - - - - - EamA k59_582197_1 1235457.C404_16500 2.4e-57 182.0 COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,2VJXP@28216|Betaproteobacteria,1KFG6@119060|Burkholderiaceae 28216|Betaproteobacteria C formate dehydrogenase fdhB - - ko:K00124,ko:K07307 ko00630,ko00680,ko00920,ko01100,ko01120,ko01200,map00630,map00680,map00920,map01100,map01120,map01200 - R00519,R09501 RC02555,RC02796 ko00000,ko00001,ko02000 5.A.3.3 - - Fer4_11,Fer4_7 k59_582197_2 1217718.ALOU01000083_gene2978 1.44e-57 198.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,1K5NF@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family fdhA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k59_1534231_2 1452718.JBOY01000158_gene997 1.6e-62 199.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the peptidase M48B family htpX GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 k59_532764_1 153948.NAL212_2932 4.4e-100 315.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,371VQ@32003|Nitrosomonadales 28216|Betaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD k59_1182351_1 1144305.PMI02_04505 2.53e-50 181.0 COG0369@1|root,COG3182@1|root,COG0369@2|Bacteria,COG3182@2|Bacteria,1MWYV@1224|Proteobacteria,2TW5P@28211|Alphaproteobacteria,2K3CY@204457|Sphingomonadales 204457|Sphingomonadales P Flavodoxin - - 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - Flavodoxin_1,NAD_binding_1,PepSY_TM k59_336242_1 32042.PstZobell_16381 4.3e-34 133.0 COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,1RNET@1236|Gammaproteobacteria,1Z0CD@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport oprC - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_980046_1 270374.MELB17_10473 1.59e-41 145.0 COG3638@1|root,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,1RRV7@1236|Gammaproteobacteria,46AEY@72275|Alteromonadaceae 1236|Gammaproteobacteria P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran k59_83515_1 1500893.JQNB01000001_gene1400 7.43e-166 468.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,1RMAT@1236|Gammaproteobacteria,1X4DA@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM k59_833865_1 1458697.W6E8I4_9CAUD 7.08e-36 139.0 4QFDB@10239|Viruses,4QVA2@35237|dsDNA viruses no RNA stage,4QTSF@28883|Caudovirales,4QN7V@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_1033146_1 1499686.BN1079_01891 6.85e-51 163.0 2EUNX@1|root,33N4S@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_1432704_1 391008.Smal_2353 5.19e-44 165.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1X4HX@135614|Xanthomonadales 135614|Xanthomonadales P TonB-dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k59_486987_1 1234364.AMSF01000056_gene1223 4.1e-68 231.0 COG2911@1|root,COG3210@1|root,COG4625@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,1X5BV@135614|Xanthomonadales 135614|Xanthomonadales U Large exoproteins involved in heme utilization or adhesion - - - - - - - - - - - - Haemagg_act k59_732630_2 745411.B3C1_00930 1.17e-69 210.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1J6Q9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - ko:K06891 - - - - ko00000 - - - ClpS k59_1333846_1 500632.CLONEX_00543 0.000615 46.6 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia 186801|Clostridia O SPFH Band 7 PHB domain protein qmcA - - - - - - - - - - - Band_7 k59_1333846_2 1234364.AMSF01000025_gene3698 6.69e-21 87.8 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1X4ZH@135614|Xanthomonadales 135614|Xanthomonadales J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k59_487200_1 1234364.AMSF01000010_gene600 1.57e-51 171.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1X34S@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k59_1333849_1 301.JNHE01000027_gene3006 1.11e-106 317.0 COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RMVU@1236|Gammaproteobacteria,1YES1@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH k59_1182821_1 292.DM42_1809 5.71e-23 100.0 COG3511@1|root,COG3511@2|Bacteria,1MWVP@1224|Proteobacteria,2VMZ4@28216|Betaproteobacteria,1K02T@119060|Burkholderiaceae 28216|Betaproteobacteria M phospholipase C - - 3.1.4.3 ko:K01114 ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919 - R01312,R02027,R02052,R03332,R07381 RC00017,RC00425 ko00000,ko00001,ko01000,ko02042 - - - DUF756,Phosphoesterase,TAT_signal k59_637408_1 1444711.CCJF01000005_gene1428 6.82e-66 218.0 COG4108@1|root,COG4108@2|Bacteria,2JFKT@204428|Chlamydiae 204428|Chlamydiae J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP - - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,RF3_C k59_782916_1 1163407.UU7_15220 9.54e-99 310.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1X51M@135614|Xanthomonadales 135614|Xanthomonadales L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k59_782952_1 1234364.AMSF01000088_gene2763 8.25e-89 271.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,1X4VN@135614|Xanthomonadales 135614|Xanthomonadales D Reduces the stability of FtsZ polymers in the presence of ATP zapE - - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase k59_1535014_1 1234364.AMSF01000075_gene1948 5.94e-44 150.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1X3PT@135614|Xanthomonadales 135614|Xanthomonadales Q abc transporter atp-binding protein - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran k59_1535014_2 1234364.AMSF01000075_gene1949 2.65e-24 96.7 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1X4E7@135614|Xanthomonadales 135614|Xanthomonadales F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin k59_1481488_1 301.JNHE01000016_gene4481 2.13e-141 415.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,1S1X3@1236|Gammaproteobacteria,1YFDB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 k59_377083_1 686578.AFFX01000003_gene367 1.42e-83 261.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Protein of unknown function (DUF1302) - - - - - - - - - - - - DUF1302 k59_337216_1 1500893.JQNB01000001_gene2547 2.6e-53 175.0 COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,1RRFC@1236|Gammaproteobacteria,1X4B2@135614|Xanthomonadales 135614|Xanthomonadales EM Belongs to the DapA family dapA2 - 3.5.4.22 ko:K21062 ko00330,map00330 - R02280 RC00679 ko00000,ko00001,ko01000 - - - DHDPS k59_337216_2 1163407.UU7_11175 5.4e-33 125.0 COG0446@1|root,COG0446@2|Bacteria,1MXA9@1224|Proteobacteria,1RSF2@1236|Gammaproteobacteria,1X48V@135614|Xanthomonadales 135614|Xanthomonadales C Oxidoreductase - - - - - - - - - - - - Pyr_redox_2 k59_683627_1 330214.NIDE3271 7.81e-104 306.0 COG2180@1|root,COG2180@2|Bacteria 2|Bacteria C chaperone-mediated protein complex assembly narJ GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - ko:K00373,ko:K17052 ko02020,map02020 - - - ko00000,ko00001,ko02000 5.A.3.8 - iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687 Nitrate_red_del k59_337264_1 715451.ambt_10315 1.19e-56 199.0 COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,4645Y@72275|Alteromonadaceae 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CZB,DUF4118,EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Protoglobin k59_377271_1 1349785.BAUG01000025_gene1528 1.81e-10 61.6 COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1HXA8@117743|Flavobacteriia 976|Bacteroidetes M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k59_377271_2 1056512.D515_00402 7.71e-53 180.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1XUMH@135623|Vibrionales 135623|Vibrionales M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M k59_1284708_1 1234364.AMSF01000005_gene788 1.6e-95 290.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1X3ZX@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c k59_583303_1 95619.PM1_0206765 6.62e-106 320.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k59_583303_2 399739.Pmen_3687 1.59e-28 103.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1YGDC@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 k59_533811_1 1380394.JADL01000004_gene6060 4.63e-64 216.0 COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,2JSZE@204441|Rhodospirillales 204441|Rhodospirillales C Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - - - - - - - - - - - TPP_enzyme_C k59_733325_1 95619.PM1_0217900 2.34e-100 300.0 COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria 1224|Proteobacteria S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox k59_1238805_1 926561.KB900622_gene462 1.04e-62 208.0 COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,3WB6M@53433|Halanaerobiales 186801|Clostridia L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase k59_981122_1 76114.ebA2266 3.15e-44 153.0 COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,2VH6W@28216|Betaproteobacteria,2KV8N@206389|Rhodocyclales 206389|Rhodocyclales NU Pilus assembly protein pilM - - ko:K02662 - - - - ko00000,ko02035,ko02044 - - - PilM_2 k59_981122_2 748247.AZKH_4222 1.36e-48 171.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,2KU7U@206389|Rhodocyclales 206389|Rhodocyclales M penicillin-binding protein 1A mcrA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase k59_1481953_1 1268237.G114_06337 2.65e-08 50.8 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1Y4NC@135624|Aeromonadales 135624|Aeromonadales J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ - - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 k59_1481953_2 1448139.AI20_17875 3.11e-33 115.0 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1Y4U3@135624|Aeromonadales 135624|Aeromonadales J Belongs to the universal ribosomal protein uL29 family rpmC - - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 k59_1481953_3 1448139.AI20_17880 2.62e-69 210.0 COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,1Y4F9@135624|Aeromonadales 135624|Aeromonadales J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP - - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 k59_1183501_1 519989.ECTPHS_02169 1.77e-93 283.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1WWB3@135613|Chromatiales 135613|Chromatiales L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N k59_1481999_1 1234364.AMSF01000095_gene2544 6.59e-169 481.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X3II@135614|Xanthomonadales 135614|Xanthomonadales T CheY-like receiver AAA-type ATPase and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k59_583554_1 95619.PM1_0200755 2.9e-25 101.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L k59_583554_2 287.DR97_3674 6.34e-79 235.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,1YFWF@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Ribosomal protein L17 rplQ GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 k59_84854_1 999541.bgla_2g17070 8.08e-85 266.0 COG0477@1|root,COG0477@2|Bacteria,1QTWJ@1224|Proteobacteria,2WGG4@28216|Betaproteobacteria,1KIRA@119060|Burkholderiaceae 28216|Betaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k59_933832_1 1234364.AMSF01000002_gene2311 2.22e-34 130.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1X57Q@135614|Xanthomonadales 135614|Xanthomonadales S M61 glycyl aminopeptidase - - - - - - - - - - - - Peptidase_M61 k59_638342_1 85643.Tmz1t_2771 1.35e-82 261.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,2VHSM@28216|Betaproteobacteria,2KVUD@206389|Rhodocyclales 206389|Rhodocyclales P Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N k59_684207_1 745411.B3C1_16601 1.84e-57 190.0 COG1714@1|root,COG1714@2|Bacteria,1R6WK@1224|Proteobacteria,1RYVD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S PFAM RDD domain containing protein - - - - - - - - - - - - RDD k59_1433829_1 1452718.JBOY01000005_gene3306 5.85e-76 234.0 28IHQ@1|root,2Z8IX@2|Bacteria,1PZJF@1224|Proteobacteria,1S1AH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3313) - - - - - - - - - - - - DUF3313 k59_85013_1 745411.B3C1_00875 9.33e-90 276.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1J4GH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iJN746.PP_4678,iLF82_1304.LF82_1103 IlvC,IlvN k59_1482207_1 1163407.UU7_14063 1.82e-107 327.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1X49W@135614|Xanthomonadales 135614|Xanthomonadales S mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth uup - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn k59_981425_1 1163407.UU7_04837 2.68e-126 375.0 COG3979@1|root,COG3979@2|Bacteria,1R5T0@1224|Proteobacteria,1RQXW@1236|Gammaproteobacteria,1X473@135614|Xanthomonadales 135614|Xanthomonadales S Chitin-binding domain type 3 - - - - - - - - - - - - - k59_1285217_1 1229909.NSED_05750 8.32e-62 192.0 arCOG05565@1|root,arCOG05565@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_1285217_2 85982.XP_007323078.1 6.49e-10 58.5 COG0225@1|root,KOG1635@2759|Eukaryota,39U04@33154|Opisthokonta,3P2RD@4751|Fungi,3V0RY@5204|Basidiomycota,22527@155619|Agaricomycetes 4751|Fungi O methionine sulfoxide reductase mxr1 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0017144,GO:0019538,GO:0019752,GO:0030091,GO:0033554,GO:0033744,GO:0034599,GO:0036456,GO:0042221,GO:0043094,GO:0043102,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990355 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR k59_337969_1 1357275.AVEL02000131_gene267 1.1e-47 175.0 COG4625@1|root,COG4625@2|Bacteria,1MU92@1224|Proteobacteria 1224|Proteobacteria EHJ outer membrane autotransporter barrel domain - - - ko:K12685 - - - - ko00000,ko01000,ko02000,ko02044 1.B.12.5.1,1.B.12.5.3 - - Autotransporter,PATR,Peptidase_S8 k59_1482261_1 1144319.PMI16_03629 9.33e-92 281.0 COG5002@1|root,COG5002@2|Bacteria,1QTV1@1224|Proteobacteria,2WGQF@28216|Betaproteobacteria,473P0@75682|Oxalobacteraceae 28216|Betaproteobacteria T Member of a two-component regulatory system - - 2.7.13.3 ko:K07644 ko02020,map02020 M00452,M00745 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,HisKA k59_1482261_2 1144319.PMI16_03630 1.04e-13 68.9 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2VHHB@28216|Betaproteobacteria,473CG@75682|Oxalobacteraceae 28216|Betaproteobacteria K Heavy metal response - - - ko:K07665 ko02020,map02020 M00452,M00745 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C k59_1482283_1 1229909.NSED_08930 1.87e-30 117.0 arCOG10597@1|root,arCOG10597@2157|Archaea 2157|Archaea O serine-type endopeptidase activity - - - - - - - - - - - - - k59_1183817_1 95619.PM1_0228955 1.46e-196 546.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria 1236|Gammaproteobacteria J glycyl-tRNA synthetase alpha subunit glyQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iAF1260.b3560,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 tRNA-synt_2e k59_264124_1 477228.YO5_01434 2.73e-106 318.0 COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1Z0U8@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E COG1760 L-serine deaminase sdaA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta k59_1158222_2 1234364.AMSF01000013_gene652 4.57e-41 145.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,1X2YT@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the bacterial glucokinase family glk2 - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase k59_57294_1 301.JNHE01000006_gene1103 1.18e-117 351.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,1YFG4@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate betA GO:0001505,GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0006113,GO:0006575,GO:0006577,GO:0006578,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008812,GO:0009058,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0019285,GO:0019695,GO:0031455,GO:0031456,GO:0034641,GO:0042133,GO:0042398,GO:0044237,GO:0044249,GO:0044271,GO:0050896,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1679,iECDH10B_1368.ECDH10B_0298,iECDH1ME8569_1439.ECDH1ME8569_0299,iECH74115_1262.ECH74115_0373,iECOK1_1307.ECOK1_0305,iECS88_1305.ECS88_0319,iECSP_1301.ECSP_0366,iECs_1301.ECs0357,iEcDH1_1363.EcDH1_3295,iEcolC_1368.EcolC_3312,iG2583_1286.G2583_0415,iJN746.PP_5064,iJO1366.b0311,iUMN146_1321.UM146_15745,iY75_1357.Y75_RS01610,iZ_1308.Z0398 GMC_oxred_C,GMC_oxred_N k59_1007863_1 1229909.NSED_09835 2.41e-72 223.0 COG1100@1|root,arCOG01225@2157|Archaea,41T0A@651137|Thaumarchaeota 651137|Thaumarchaeota S Conserved hypothetical ATP binding protein - - - ko:K06883 - - - - ko00000 - - - ATP_bind_1 k59_1007863_2 436308.Nmar_0041 3e-21 90.9 COG0083@1|root,arCOG01027@2157|Archaea,41S89@651137|Thaumarchaeota 651137|Thaumarchaeota E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB - 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N k59_264306_1 1356852.N008_11100 3.95e-18 89.4 COG4251@1|root,COG4251@2|Bacteria,4NE3J@976|Bacteroidetes,47KK5@768503|Cytophagia 976|Bacteroidetes T PAS domain - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9 k59_1007938_1 1500890.JQNL01000001_gene648 5.83e-53 169.0 COG0599@1|root,COG0599@2|Bacteria,1N38Z@1224|Proteobacteria,1S5G6@1236|Gammaproteobacteria,1X6C8@135614|Xanthomonadales 135614|Xanthomonadales S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD k59_1007938_2 666685.R2APBS1_2607 7.85e-49 156.0 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,1X7E1@135614|Xanthomonadales 135614|Xanthomonadales O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin k59_407699_1 1182590.BN5_02606 1.74e-116 344.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,1YJ4R@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Metal dependent phosphohydrolases with conserved 'HD' motif. dgt - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD k59_807768_1 1163407.UU7_04307 1.36e-40 137.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1X7QA@135614|Xanthomonadales 135614|Xanthomonadales J modulation protein raiA - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE k59_1307875_1 1234364.AMSF01000015_gene3186 1.4e-92 302.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,1X46R@135614|Xanthomonadales 135614|Xanthomonadales E glutamate dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH,GDH_N k59_164378_1 911239.CF149_13275 7.58e-60 194.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily hcaT - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like k59_164378_2 930166.CD58_22010 1.05e-53 177.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2469,iEC55989_1330.EC55989_2573,iECO103_1326.ECO103_2794,iECO111_1330.ECO111_3077,iECO26_1355.ECO26_3317,iECSE_1348.ECSE_2638,iECW_1372.ECW_m2518,iEKO11_1354.EKO11_1436,iSSON_1240.SSON_2387,iUMNK88_1353.UMNK88_2882,iWFL_1372.ECW_m2518 Chorismate_synt k59_1365317_1 93220.LV28_03660 1.16e-08 57.4 COG5455@1|root,COG5455@2|Bacteria,1NGVG@1224|Proteobacteria,2VVTN@28216|Betaproteobacteria,1KA79@119060|Burkholderiaceae 28216|Betaproteobacteria S Nickel/cobalt transporter regulator - - - - - - - - - - - - RcnB k59_114488_1 436308.Nmar_0101 4.52e-109 333.0 COG0464@1|root,arCOG01308@2157|Archaea,41SB6@651137|Thaumarchaeota 651137|Thaumarchaeota O Cell division protein 48 (CDC48), domain 2 - - - ko:K13525 ko04141,ko05134,map04141,map05134 M00400,M00403 - - ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 3.A.16.1 - - AAA,CDC48_2,CDC48_N k59_1108093_1 1123368.AUIS01000009_gene2449 1.73e-55 186.0 COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,1RPGR@1236|Gammaproteobacteria,2NCP1@225057|Acidithiobacillales 225057|Acidithiobacillales S FIST N domain - - - - - - - - - - - - FIST,FIST_C k59_264540_2 1123487.KB892841_gene4306 9.58e-51 179.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,2KUXR@206389|Rhodocyclales 206389|Rhodocyclales J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 k59_114526_1 1234364.AMSF01000082_gene3015 6.84e-77 232.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,1S5XY@1236|Gammaproteobacteria,1X6CA@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - ko:K08973 - - - - ko00000 - - - UPF0093 k59_757877_1 998088.B565_3051 2.75e-72 223.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,1Y3KM@135624|Aeromonadales 135624|Aeromonadales I Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf k59_1365376_1 547042.BACCOPRO_03836 1.38e-42 151.0 COG3507@1|root,COG3507@2|Bacteria,4PKZY@976|Bacteroidetes,2G09G@200643|Bacteroidia,4AV4I@815|Bacteroidaceae 976|Bacteroidetes G Glycosyl hydrolases family 43 - - - - - - - - - - - - Glyco_hydro_43 k59_1383121_1 1234364.AMSF01000064_gene2191 4.29e-108 323.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1X2YH@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 k59_282311_1 32042.PstZobell_18505 5.77e-99 303.0 COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria,1Z05K@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria O carbamoyl transferase, NodU family HA62_32075 - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N k59_282311_2 1123020.AUIE01000003_gene468 5.95e-24 99.8 COG0515@1|root,COG0515@2|Bacteria,1R47Q@1224|Proteobacteria,1S6YE@1236|Gammaproteobacteria,1YDXK@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria KLT Lipopolysaccharide kinase (Kdo/WaaP) family - - - - - - - - - - - - Kdo k59_882119_1 666685.R2APBS1_1510 6.06e-60 191.0 2A4M7@1|root,30T81@2|Bacteria,1PCXE@1224|Proteobacteria,1SY2Z@1236|Gammaproteobacteria,1X75N@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - DUF2884 k59_1168828_1 436308.Nmar_1721 7.01e-103 311.0 COG0452@1|root,arCOG01704@2157|Archaea,41SYG@651137|Thaumarchaeota 651137|Thaumarchaeota H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine - - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein k59_1120173_1 666685.R2APBS1_3615 1.58e-86 264.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,1RPX5@1236|Gammaproteobacteria,1X56H@135614|Xanthomonadales 135614|Xanthomonadales C oxidoreductases (related to aryl-alcohol dehydrogenases) - - - - - - - - - - - - Aldo_ket_red k59_819760_1 436308.Nmar_0061 4.63e-56 179.0 COG5491@1|root,arCOG00452@2157|Archaea,41SJ3@651137|Thaumarchaeota 651137|Thaumarchaeota D conserved protein implicated in secretion - - - - - - - - - - - - - k59_819760_2 1229909.NSED_09930 4.36e-15 72.8 COG1794@1|root,arCOG02005@2157|Archaea,41SM4@651137|Thaumarchaeota 651137|Thaumarchaeota M Asp/Glu/Hydantoin racemase - - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race k59_182178_1 745411.B3C1_08636 1.27e-121 364.0 COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,1RN74@1236|Gammaproteobacteria,1J4XK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB hscA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - ko:K04044 - - - - ko00000,ko03110 1.A.33 - - HSP70 k59_1583269_1 1229909.NSED_09625 7.89e-32 116.0 arCOG08041@1|root,arCOG08041@2157|Archaea,41SRT@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - HTH_27 k59_1583269_2 436308.Nmar_1798 2.02e-27 99.8 arCOG00818@1|root,arCOG00818@2157|Archaea 2157|Archaea S AbrB family - - - - - - - - - - - - MazE_antitoxin k59_1470680_1 767434.Fraau_2109 4.89e-119 352.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1X32I@135614|Xanthomonadales 135614|Xanthomonadales E Acetylglutamate kinase argB GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 ko:K22478 ko00220,ko01210,ko01230,map00220,map01210,map01230 M00028,M00845 R00259,R02649 RC00002,RC00004,RC00043,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,NAT k59_471029_1 436308.Nmar_1488 9.69e-77 245.0 COG0072@1|root,arCOG00412@2157|Archaea,41S8M@651137|Thaumarchaeota 651137|Thaumarchaeota J phenylalanyl-tRNA synthetase, beta subunit - - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5 k59_232383_1 521719.ATXQ01000001_gene701 7.42e-67 216.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1YDVG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Glutamine synthetase, beta-Grasp domain glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - iJN746.PP_5046 Gln-synt_C,Gln-synt_N k59_1520617_1 330214.NIDE4347 2.82e-10 59.7 COG0065@1|root,COG0065@2|Bacteria,3J0IH@40117|Nitrospirae 40117|Nitrospirae H Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k59_1520617_2 330214.NIDE4343 3.93e-32 117.0 2C3ZQ@1|root,32SCF@2|Bacteria 2|Bacteria S MEKHLA domain - - - - - - - - - - - - MEKHLA k59_967135_1 323848.Nmul_A0180 8.32e-76 239.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2VHJJ@28216|Betaproteobacteria,3724N@32003|Nitrosomonadales 28216|Betaproteobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b k59_967135_2 488538.SAR116_2071 3.45e-14 67.8 2DQZQ@1|root,339JR@2|Bacteria,1NNI2@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - k59_768867_1 595537.Varpa_5526 1.29e-27 114.0 29T6F@1|root,30ED6@2|Bacteria,1N44X@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function (DUF4123) - - - - - - - - - - - - DUF4123 k59_1319425_2 1234364.AMSF01000005_gene738 1.99e-97 291.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,1RQXJ@1236|Gammaproteobacteria,1X33D@135614|Xanthomonadales 135614|Xanthomonadales P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 k59_182423_1 1448139.AI20_17815 2.82e-115 341.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1Y3V0@135624|Aeromonadales 135624|Aeromonadales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k59_1270132_2 1215092.PA6_007_00370 1.76e-40 145.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,1YF5A@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,Response_reg k59_1520696_1 472759.Nhal_3009 6.51e-36 127.0 COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1WYQ1@135613|Chromatiales 135613|Chromatiales L DNA polymerase III, chi subunit - - 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi k59_1069064_1 1500890.JQNL01000001_gene357 1.19e-50 182.0 COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RQCR@1236|Gammaproteobacteria,1X4SZ@135614|Xanthomonadales 135614|Xanthomonadales T diguanylate cyclase - - - - - - - - - - - - GGDEF,Reg_prop,Y_Y_Y k59_1583770_1 395495.Lcho_3752 9.13e-39 138.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,1KMC1@119065|unclassified Burkholderiales 28216|Betaproteobacteria G subfamily IA, variant 1 gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k59_471499_2 1122185.N792_04650 4.02e-38 134.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1X6FV@135614|Xanthomonadales 135614|Xanthomonadales D Maf-like protein - - - ko:K06287 - - - - ko00000 - - - Maf k59_283096_1 395493.BegalDRAFT_2338 1.35e-69 234.0 COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg k59_569114_1 1163409.UUA_13415 3.68e-50 181.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1X5F3@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor proteins mostly Fe transport - - - - - - - - - - - - Plug,TonB_dep_Rec k59_882935_1 1439940.BAY1663_03239 0.000176 43.9 COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,1RPWM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phenazine biosynthesis protein PhzF pab - - - - - - - - - - - PhzC-PhzF k59_882935_2 1242864.D187_004713 1.74e-56 181.0 COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,42M0E@68525|delta/epsilon subdivisions,2WV66@28221|Deltaproteobacteria,2YZ5C@29|Myxococcales 28221|Deltaproteobacteria C NADH dehydrogenase NAD(P)H nitroreductase - - - ko:K09019 ko00240,ko01100,map00240,map01100 - R09289 RC00087 ko00000,ko00001,ko01000 - - - Nitroreductase k59_519326_1 1234364.AMSF01000025_gene3645 4.81e-37 135.0 COG0457@1|root,COG0457@2|Bacteria,1MVH9@1224|Proteobacteria,1RQ3R@1236|Gammaproteobacteria,1X3F2@135614|Xanthomonadales 135614|Xanthomonadales S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_8 k59_1270468_1 502025.Hoch_3278 1.23e-18 92.8 COG0745@1|root,COG1340@1|root,COG1352@1|root,COG2201@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG0745@2|Bacteria,COG1340@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions,2X6YR@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase A domain protein - - - - - - - - - - - - DUF3365,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg k59_883022_1 946483.Cenrod_2398 1.47e-09 63.2 COG2199@1|root,COG2703@1|root,COG5000@1|root,COG2199@2|Bacteria,COG2703@2|Bacteria,COG5000@2|Bacteria,1QZY3@1224|Proteobacteria 1224|Proteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF,Hemerythrin,PAS_9 k59_1383996_1 402626.Rpic_3861 7.55e-87 264.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VI8S@28216|Betaproteobacteria,1K0C0@119060|Burkholderiaceae 28216|Betaproteobacteria G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB - 4.1.3.30,5.4.2.9 ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 - R00409,R00661 RC00286,RC00287,RC02792 ko00000,ko00001,ko01000 - - - PEP_mutase k59_1069466_1 1234364.AMSF01000055_gene1075 5.07e-102 302.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1X30F@135614|Xanthomonadales 135614|Xanthomonadales M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT k59_1069466_2 1234364.AMSF01000055_gene1074 1.51e-37 134.0 COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,1RZ6E@1236|Gammaproteobacteria,1X38A@135614|Xanthomonadales 135614|Xanthomonadales S Mitochondrial biogenesis AIM24 - - - - - - - - - - - - AIM24 k59_1471325_1 454957.IA64_11080 4.72e-43 160.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1X5K7@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k59_1270654_2 318167.Sfri_0054 3.49e-20 93.2 COG1145@1|root,COG1145@2|Bacteria,1MWHY@1224|Proteobacteria,1RZ4B@1236|Gammaproteobacteria,2QA5E@267890|Shewanellaceae 1236|Gammaproteobacteria C PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - - - - - - - - - - Fer4,Fer4_10,Fer4_7 k59_1320025_1 1234364.AMSF01000016_gene1614 1.01e-116 339.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,1X4MM@135614|Xanthomonadales 135614|Xanthomonadales O peptidylprolyl - - 5.2.1.8 ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N k59_1169653_1 1163409.UUA_01911 1.94e-91 275.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1X3EY@135614|Xanthomonadales 135614|Xanthomonadales M Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 k59_70232_2 1123393.KB891326_gene69 1.07e-10 61.6 COG1748@1|root,COG1748@2|Bacteria,1QY0D@1224|Proteobacteria 1224|Proteobacteria E Saccharopine dehydrogenase - - 1.4.1.16 ko:K03340 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00526 R02755 RC00006 ko00000,ko00001,ko00002,ko01000 - - - DAPDH_C k59_21311_1 198804.BUsg_536 2.73e-08 59.3 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,1RPU9@1236|Gammaproteobacteria,37D0V@32199|Buchnera 1236|Gammaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - iAPECO1_1312.APECO1_2496,iEC042_1314.EC042_4342,iECOK1_1307.ECOK1_4443,iECS88_1305.ECS88_4426,iPC815.YPO3909,iUMN146_1321.UM146_20110,iUTI89_1310.UTI89_C4562 Asp_Glu_race k59_1069703_1 436308.Nmar_1700 8.66e-09 55.5 COG1527@1|root,arCOG02459@2157|Archaea,41T18@651137|Thaumarchaeota 651137|Thaumarchaeota C ATP synthase (C/AC39) subunit - - - ko:K02119 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - vATP-synt_AC39 k59_1069703_2 1229909.NSED_09060 1.28e-18 81.6 COG1468@1|root,arCOG00790@2157|Archaea,41T4T@651137|Thaumarchaeota 651137|Thaumarchaeota V CRISPR-associated protein Cas4 - - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - - k59_1121068_1 1265502.KB905961_gene332 8.08e-88 283.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,4ACV8@80864|Comamonadaceae 28216|Betaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family fdhA - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding k59_1584527_1 1229909.NSED_05840 2.32e-95 298.0 COG0145@1|root,arCOG01511@2157|Archaea,41SZ7@651137|Thaumarchaeota 651137|Thaumarchaeota E N-methylhydantoinase A acetone carboxylase, beta subunit - - - - - - - - - - - - Hydant_A_N,Hydantoinase_A k59_622092_2 267608.RSp1083 2.54e-39 141.0 COG2064@1|root,COG2064@2|Bacteria,1RBXN@1224|Proteobacteria,2VQES@28216|Betaproteobacteria,1K43U@119060|Burkholderiaceae 28216|Betaproteobacteria NU Type II secretion system tadC - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF k59_70390_1 1265503.KB905176_gene4040 1.13e-19 90.5 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,2Q6RI@267889|Colwelliaceae 1236|Gammaproteobacteria D TolA binding protein trimerisation cpoB GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri k59_1320243_1 301.JNHE01000024_gene2465 7.82e-13 62.4 2E30J@1|root,32Y12@2|Bacteria,1N707@1224|Proteobacteria,1SCST@1236|Gammaproteobacteria,1YH89@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S ParD-like antitoxin of type II bacterial toxin-antitoxin system - - - - - - - - - - - - ParD_like k59_419336_1 1163408.UU9_07551 1.39e-37 134.0 COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,1RNNP@1236|Gammaproteobacteria,1X3IY@135614|Xanthomonadales 135614|Xanthomonadales S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 k59_419336_2 1234364.AMSF01000075_gene1927 2.32e-65 208.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,1X580@135614|Xanthomonadales 135614|Xanthomonadales S ATPase (AAA - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 k59_419429_1 1123354.AUDR01000014_gene1074 1.24e-69 219.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,1KRHN@119069|Hydrogenophilales 119069|Hydrogenophilales F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N k59_419429_2 1131553.JIBI01000017_gene580 4.59e-57 183.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,37239@32003|Nitrosomonadales 28216|Betaproteobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C k59_1080457_2 1123367.C666_03380 7.41e-49 160.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2VQD9@28216|Betaproteobacteria,2KUI7@206389|Rhodocyclales 206389|Rhodocyclales C COG1905 NADH ubiquinone oxidoreductase 24 kD subunit nuoE - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx k59_248752_1 1121939.L861_10635 2.14e-08 54.7 COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,1RQ6K@1236|Gammaproteobacteria,1XPQ3@135619|Oceanospirillales 135619|Oceanospirillales P Formate transporter - - - - - - - - - - - - Form_Nir_trans k59_248752_2 1196835.A458_00060 2.65e-49 165.0 COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,1RSP8@1236|Gammaproteobacteria,1Z13W@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH k59_429793_1 1276756.AUEX01000036_gene1199 2.77e-210 601.0 COG3451@1|root,COG3451@2|Bacteria,1MXH0@1224|Proteobacteria,2VKE0@28216|Betaproteobacteria,4AD8U@80864|Comamonadaceae 28216|Betaproteobacteria U CagE, TrbE, VirB family, component of type IV transporter system - - - ko:K20530 ko02024,map02024 - - - ko00000,ko00001,ko02044 3.A.7.4 - - CagE_TrbE_VirB k59_1479227_1 1304275.C41B8_03946 1.5e-60 201.0 COG0531@1|root,COG0531@2|Bacteria 2|Bacteria E amino acid potE - - ko:K16263 - - - - ko00000,ko02000 2.A.3.13 - - AA_permease_2 k59_780143_1 1182590.BN5_00778 2.37e-86 281.0 COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,1RQFM@1236|Gammaproteobacteria,1YDV3@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Putative exonuclease SbcCD, C subunit sbcC GO:0000014,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576,GO:1990238 - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C k59_1030591_1 1163409.UUA_02646 1.28e-92 285.0 COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,1RRNW@1236|Gammaproteobacteria,1X5B8@135614|Xanthomonadales 135614|Xanthomonadales G Major facilitator superfamily - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 k59_31955_1 322710.Avin_28640 9.53e-27 113.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HAMP,MASE3,PAS_8,PAS_9,SBP_bac_3 k59_148523_1 436308.Nmar_0629 1.38e-20 86.7 arCOG01781@1|root,arCOG01781@2157|Archaea,41T0U@651137|Thaumarchaeota 651137|Thaumarchaeota Q Protein of unknown function (DUF1698) - - - - - - - - - - - - Methyltransf_11 k59_530553_1 1163408.UU9_13990 4.3e-31 121.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,1X4ZR@135614|Xanthomonadales 135614|Xanthomonadales S transporter yhhT - - - - - - - - - - - AI-2E_transport k59_1598963_1 745411.B3C1_18732 1.2e-16 78.2 COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1J52Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k59_1598963_2 745411.B3C1_18727 1.54e-66 224.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1J4ZQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k59_148622_1 1472716.KBK24_0119795 4.91e-28 115.0 COG0358@1|root,COG0358@2|Bacteria,1QX15@1224|Proteobacteria,2WH3N@28216|Betaproteobacteria,1KCQ8@119060|Burkholderiaceae 28216|Betaproteobacteria L Protein of unknown function (DUF3987) - - - - - - - - - - - - DUF3987 k59_299396_1 1234364.AMSF01000001_gene2370 6.68e-110 341.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1X4SH@135614|Xanthomonadales 135614|Xanthomonadales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW k59_1430080_1 1249627.D779_0178 2.2e-141 415.0 COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales 135613|Chromatiales C reductase, alpha subunit - - 1.8.99.2 ko:K00394 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k59_81321_2 796620.VIBC2010_06414 3.6e-08 55.5 COG1280@1|root,COG1280@2|Bacteria,1RDPB@1224|Proteobacteria,1S5JJ@1236|Gammaproteobacteria,1XTFX@135623|Vibrionales 135623|Vibrionales E threonine efflux protein - - - - - - - - - - - - LysE k59_32218_1 1211579.PP4_53990 1.63e-63 207.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,1YXWR@136845|Pseudomonas putida group 1236|Gammaproteobacteria E Aspartate ammonia-lyase aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 k59_32218_2 1282356.H045_20665 3.63e-14 71.6 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria,1YPWH@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria K Transcriptional regulator - - - ko:K00375,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000,ko03000 - - - Aminotran_1_2,GntR k59_430150_1 330214.NIDE3344 1.13e-92 285.0 COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria,3J0VW@40117|Nitrospirae 40117|Nitrospirae O Trypsin - - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 k59_1399208_1 767434.Fraau_1766 7.88e-61 188.0 COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,1S60W@1236|Gammaproteobacteria,1X71K@135614|Xanthomonadales 135614|Xanthomonadales P Alkylphosphonate utilization operon protein PhnA phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon k59_591829_1 264730.PSPPH_4734 3.25e-109 334.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1Z6EX@136849|Pseudomonas syringae group 1236|Gammaproteobacteria H Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB GO:0003674,GO:0003824,GO:0004474,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0356 Malate_synthase k59_647059_1 686578.AFFX01000004_gene3725 7.66e-43 153.0 COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,1RPFK@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - ko:K00375,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000,ko03000 - - - Aminotran_1_2,GntR k59_647059_2 565045.NOR51B_2843 6.72e-07 50.1 COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1J4WY@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N k59_92699_1 1500893.JQNB01000001_gene2597 4.9e-108 327.0 COG1807@1|root,COG1807@2|Bacteria,1N57T@1224|Proteobacteria,1TD24@1236|Gammaproteobacteria,1X9YF@135614|Xanthomonadales 135614|Xanthomonadales M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 k59_1543169_1 1182590.BN5_02259 1.5e-67 216.0 COG3203@1|root,COG3203@2|Bacteria,1P7S0@1224|Proteobacteria,1S09X@1236|Gammaproteobacteria,1YDBB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Gram-negative porin - - - - - - - - - - - - Porin_4 k59_386437_1 390235.PputW619_5025 1.75e-97 295.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1YW4C@136845|Pseudomonas putida group 1236|Gammaproteobacteria E peptidase M24B, X-Pro dipeptidase aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k59_692767_1 1205753.A989_17363 1.72e-88 271.0 COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,1X32K@135614|Xanthomonadales 135614|Xanthomonadales H Belongs to the radical SAM superfamily. PqqE family pqqE - - ko:K06139 - - - - ko00000 - - - Fer4_12,Radical_SAM,SPASM k59_346942_1 925775.XVE_0544 2.2e-60 211.0 COG4103@1|root,COG4103@2|Bacteria,1MURD@1224|Proteobacteria,1RQEY@1236|Gammaproteobacteria,1XAJM@135614|Xanthomonadales 135614|Xanthomonadales S TerB-C domain - - - - - - - - - - - - TerB_C k59_1293513_1 748247.AZKH_4583 1.26e-25 100.0 COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,2VRF6@28216|Betaproteobacteria,2KV9Q@206389|Rhodocyclales 206389|Rhodocyclales O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureF - - ko:K03188 - - - - ko00000 - - - UreF k59_1293513_2 748247.AZKH_4582 6.86e-62 194.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VH2U@28216|Betaproteobacteria,2KUEE@206389|Rhodocyclales 206389|Rhodocyclales KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG ureG - - ko:K03189 - - - - ko00000 - - - cobW k59_692873_1 477184.KYC_27608 5.84e-37 136.0 COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,2VHVK@28216|Betaproteobacteria,3T918@506|Alcaligenaceae 28216|Betaproteobacteria S protein conserved in bacteria hsiJ1 - - ko:K11893 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VasE k59_542833_1 404589.Anae109_2025 1.01e-106 327.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2YUJ3@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k59_592426_1 1234364.AMSF01000085_gene2941 2.79e-67 209.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1X62Z@135614|Xanthomonadales 135614|Xanthomonadales O Thiol disulfide Interchange Protein - - - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA,Thioredoxin_4 k59_592426_2 1234364.AMSF01000085_gene2940 0.000616 41.2 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1X5HB@135614|Xanthomonadales 135614|Xanthomonadales O Thiol disulfide interchange protein - - - ko:K03673 ko01503,map01503 M00728 - - ko00000,ko00001,ko00002,ko03110 - - - DSBA,Thioredoxin_4 k59_1191217_1 767434.Fraau_0060 5.99e-14 70.9 COG0697@1|root,COG0697@2|Bacteria,1NKZB@1224|Proteobacteria,1S6BF@1236|Gammaproteobacteria,1X6C7@135614|Xanthomonadales 135614|Xanthomonadales EG Membrane - - - - - - - - - - - - EamA k59_1191217_2 1234364.AMSF01000025_gene3743 5.56e-23 99.8 COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,1RQJY@1236|Gammaproteobacteria,1X5C0@135614|Xanthomonadales 135614|Xanthomonadales E Serine carboxypeptidase - - - - - - - - - - - - Peptidase_S10 k59_441631_1 399739.Pmen_1583 8.54e-162 476.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1YF92@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom k59_647769_1 391735.Veis_1599 7.06e-33 124.0 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2VK72@28216|Betaproteobacteria,4AC52@80864|Comamonadaceae 28216|Betaproteobacteria S Mo-co oxidoreductase dimerisation domain - - 1.8.2.1 ko:K05301 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00528 RC00168 ko00000,ko00001,ko01000 - - - Mo-co_dimer,Oxidored_molyb k59_647769_2 1395571.TMS3_0100780 2e-19 81.6 COG2010@1|root,COG2010@2|Bacteria,1N7JQ@1224|Proteobacteria,1SR7U@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 k59_741784_1 1234364.AMSF01000032_gene3386 7.65e-111 325.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1X3NI@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the reversible oxidation of malate to oxaloacetate mdh GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N k59_1543718_1 648757.Rvan_3586 1.78e-11 63.9 COG4887@1|root,COG4887@2|Bacteria,1RKM1@1224|Proteobacteria,2U481@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1847) - - - - - - - - - - - - DUF1847 k59_1543718_2 1454004.AW11_02570 2.07e-17 75.9 COG4274@1|root,COG4274@2|Bacteria,1MZVV@1224|Proteobacteria,2VUPM@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM GYD family protein - - - - - - - - - - - - GYD k59_989002_1 358220.C380_09385 5.7e-61 196.0 COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria,4A9S4@80864|Comamonadaceae 28216|Betaproteobacteria S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B k59_543213_1 1234364.AMSF01000024_gene3778 1.01e-56 194.0 COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,1NSQ1@1224|Proteobacteria,1RYUZ@1236|Gammaproteobacteria,1X504@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase - - - - - - - - - - - - CHASE3,HATPase_c,HisKA,PAS_4,PAS_8,Response_reg k59_43687_1 330214.NIDE3362 3.33e-53 171.0 COG0848@1|root,COG0848@2|Bacteria,3J0T6@40117|Nitrospirae 40117|Nitrospirae U Biopolymer transport protein ExbD/TolR - - - ko:K03560 - - - - ko00000,ko02000 1.A.30.2.2 - - ExbD k59_387125_1 1149133.ppKF707_5461 9.69e-24 97.1 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,1YD1Z@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria I Phosphate acyltransferases plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k59_387125_2 95619.PM1_0228965 3.02e-56 179.0 COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria 1236|Gammaproteobacteria E D,D-heptose 1,7-bisphosphate phosphatase gmhB - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - iJN746.PP_0059 Hydrolase_like k59_1494786_1 948106.AWZT01000048_gene432 9.6e-68 214.0 COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,1K22K@119060|Burkholderiaceae 28216|Betaproteobacteria P rieske 2fe-2s alcE - 1.14.15.7 ko:K00499 ko00260,map00260 - R07409 RC00087 ko00000,ko00001,ko01000 - - - Rieske,Ring_hydroxyl_A k59_347551_1 436308.Nmar_0658 3.56e-122 360.0 COG0008@1|root,arCOG00402@2157|Archaea,41SFI@651137|Thaumarchaeota 651137|Thaumarchaeota J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b k59_1343956_1 1523503.JPMY01000003_gene4207 1.54e-05 46.2 COG0628@1|root,COG0628@2|Bacteria,1R5W4@1224|Proteobacteria,1SZYZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport k59_1343956_2 95619.PM1_0220585 1.69e-39 142.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria 1236|Gammaproteobacteria M esterase of the alpha-beta hydrolase superfamily rssA GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin k59_792168_1 1049564.TevJSym_ac00580 8.63e-74 243.0 COG2010@1|root,COG2010@2|Bacteria,1R28S@1224|Proteobacteria,1T5JD@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrome_CBB3 k59_1248790_1 1217718.ALOU01000025_gene4205 8.98e-52 176.0 COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1NXKF@1224|Proteobacteria,2W0UU@28216|Betaproteobacteria,1K4Z4@119060|Burkholderiaceae 28216|Betaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,PAS_8,PAS_9 k59_1248795_1 903818.KI912268_gene811 1.47e-75 238.0 COG0426@1|root,COG0426@2|Bacteria 2|Bacteria C nitric oxide reductase activity dfa1 - 1.6.3.4 ko:K22405 - - - - ko00000,ko01000 - - - Flavin_Reduct,Flavodoxin_1,Lactamase_B k59_843975_1 339670.Bamb_1984 6.65e-60 184.0 COG3311@1|root,COG3311@2|Bacteria,1RGX4@1224|Proteobacteria,2VXTC@28216|Betaproteobacteria,1KFPN@119060|Burkholderiaceae 28216|Betaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_17 k59_843975_2 1118235.CAJH01000023_gene1545 2.95e-81 247.0 COG5534@1|root,COG5534@2|Bacteria,1MXQ0@1224|Proteobacteria,1RPJI@1236|Gammaproteobacteria,1X50E@135614|Xanthomonadales 135614|Xanthomonadales L Replication initiator protein A - - - - - - - - - - - - RPA k59_442233_1 1454004.AW11_01132 1.89e-86 263.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2W0XT@28216|Betaproteobacteria 28216|Betaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k59_1249017_1 95619.PM1_0203215 2.84e-88 260.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression dksA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR k59_348034_1 1123377.AUIV01000003_gene1795 3.15e-29 117.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1X4MI@135614|Xanthomonadales 135614|Xanthomonadales C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase k59_44260_1 745411.B3C1_13833 1.02e-96 294.0 COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,1RNA2@1236|Gammaproteobacteria,1J6SQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P H( )-stimulated, divalent metal cation uptake system mntH GO:0000041,GO:0003674,GO:0005215,GO:0005384,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015075,GO:0015077,GO:0015078,GO:0015086,GO:0015291,GO:0015292,GO:0015293,GO:0015318,GO:0015672,GO:0015684,GO:0015691,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042221,GO:0044425,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070574,GO:0070838,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071421,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - iSF_1195.SF2457 Nramp k59_543759_1 1304883.KI912532_gene1972 2.94e-85 265.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,2KUKU@206389|Rhodocyclales 206389|Rhodocyclales O HflC and HflK could encode or regulate a protease - - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N k59_792491_1 1229205.BUPH_05469 4.2e-125 364.0 COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,2VV18@28216|Betaproteobacteria,1KGS5@119060|Burkholderiaceae 28216|Betaproteobacteria L Winged helix-turn helix - - - - - - - - - - - - HTH_29,rve k59_942721_1 550540.Fbal_1370 1.88e-114 343.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA glnS GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECIAI39_1322.ECIAI39_0637 tRNA-synt_1c,tRNA-synt_1c_C k59_648709_1 767434.Fraau_2331 1.39e-38 147.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,1X4FQ@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_1249199_1 1212548.B381_01410 3.46e-120 349.0 28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,1RNYE@1236|Gammaproteobacteria,1Z2HA@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S SIR2-like domain - - - - - - - - - - - - SIR2_2 k59_1043594_1 1195246.AGRI_02323 1.3e-168 484.0 COG3903@1|root,COG3903@2|Bacteria,1N0YT@1224|Proteobacteria,1RW05@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - - k59_387996_1 266265.Bxe_B2575 9.28e-51 180.0 COG4685@1|root,COG4685@2|Bacteria,1MY31@1224|Proteobacteria,2VNU8@28216|Betaproteobacteria,1K0RN@119060|Burkholderiaceae 28216|Betaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2138) - - - - - - - - - - - - DUF2138 k59_942899_1 1121861.KB899929_gene322 3.07e-60 197.0 2C7F6@1|root,2Z8AK@2|Bacteria,1PEE5@1224|Proteobacteria,2TTH2@28211|Alphaproteobacteria,2JR3R@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_44592_1 535289.Dtpsy_1332 3.81e-120 363.0 COG1431@1|root,COG1431@2|Bacteria,1Q24E@1224|Proteobacteria,2W0M4@28216|Betaproteobacteria 28216|Betaproteobacteria J Piwi domain - - - - - - - - - - - - Piwi k59_1249432_1 1163407.UU7_07958 2.2e-71 241.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X4NP@135614|Xanthomonadales 135614|Xanthomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07789 ko02020,map02020 M00648 - - ko00000,ko00001,ko00002,ko02000 2.A.6.2 - - ACR_tran k59_1043716_1 1234364.AMSF01000016_gene1744 1.99e-130 379.0 COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1X45S@135614|Xanthomonadales 135614|Xanthomonadales I Acyl-CoA dehydrogenase gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k59_442718_1 1500890.JQNL01000001_gene1403 3.23e-31 121.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RQ6V@1236|Gammaproteobacteria,1XCET@135614|Xanthomonadales 135614|Xanthomonadales V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran k59_442718_2 2342.SOPEG_2310 9.02e-05 47.4 COG0642@1|root,COG2205@2|Bacteria,1QTVU@1224|Proteobacteria,1RPFY@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase phoQ GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010350,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,HisKA,PhoQ_Sensor k59_94293_1 1229909.NSED_00025 2.15e-53 177.0 COG1467@1|root,arCOG04110@2157|Archaea,41SCB@651137|Thaumarchaeota 651137|Thaumarchaeota L Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair priS - - ko:K02683 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DNA_primase_S k59_94293_2 1229909.NSED_00020 7.74e-44 151.0 COG2219@1|root,arCOG03013@2157|Archaea,41SCD@651137|Thaumarchaeota 651137|Thaumarchaeota L Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair priL - - ko:K18882 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DNA_primase_lrg k59_1442864_1 1411123.JQNH01000001_gene2122 7.3e-84 264.0 COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Dehydrogenase nuoEF - 1.17.1.9 ko:K00122 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - 2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB k59_1442864_2 1207063.P24_15746 2.35e-06 48.1 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria,2JQ15@204441|Rhodospirillales 204441|Rhodospirillales C Formate dehydrogenase subunit alpha - - - - - - - - - - - - Fer2_4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding k59_94347_1 1245471.PCA10_21880 3.39e-67 227.0 COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1YFZG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg k59_593968_1 366649.XFF4834R_chr02650 9.68e-75 250.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,1X3CF@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor for ferrienterochelin and colicins - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k59_943115_1 398578.Daci_2406 1.68e-17 82.8 COG3181@1|root,COG3181@2|Bacteria,1PZK3@1224|Proteobacteria,2VJ65@28216|Betaproteobacteria,4ABJ7@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC k59_943115_2 331869.BAL199_29922 7.04e-45 151.0 COG5553@1|root,COG5553@2|Bacteria,1RD6A@1224|Proteobacteria,2U7HF@28211|Alphaproteobacteria,4BT3J@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S metal-dependent enzyme of the double-stranded beta helix superfamily - - - - - - - - - - - - - k59_1295249_1 1545915.JROG01000001_gene316 1.78e-16 80.1 COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,2TSIF@28211|Alphaproteobacteria,2K209@204457|Sphingomonadales 204457|Sphingomonadales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short k59_5669_1 1459636.NTE_01238 3.1e-11 61.6 COG1522@1|root,arCOG01117@2157|Archaea 1459636.NTE_01238|- K COG1522 Transcriptional regulators - - - - - - - - - - - - - k59_5669_2 1459636.NTE_02516 2.09e-23 94.7 COG1714@1|root,arCOG03633@2157|Archaea,41T5P@651137|Thaumarchaeota 651137|Thaumarchaeota S membrane protein domain - - - - - - - - - - - - RDD k59_1205416_1 76869.PputGB1_3306 3.09e-94 284.0 COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,1YZBS@136845|Pseudomonas putida group 1236|Gammaproteobacteria C Oxidoreductase FAD-binding domain dmpP GO:0003674,GO:0003824,GO:0004497,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0018662,GO:0018958,GO:0018959,GO:0019336,GO:0019439,GO:0044237,GO:0044248,GO:0046191,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 1.6.5.8 ko:K00351,ko:K16246 ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220 M00548 R03560,R03608,R10042,R10043 RC00046,RC00490 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k59_404787_1 76114.ebA3608 1.1e-71 233.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria,2KUVM@206389|Rhodocyclales 206389|Rhodocyclales E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF k59_54561_1 666685.R2APBS1_3165 4.63e-86 275.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1X479@135614|Xanthomonadales 135614|Xanthomonadales M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k59_158648_1 1469245.JFBG01000009_gene574 7.7e-67 219.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1WX77@135613|Chromatiales 135613|Chromatiales H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC - 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM k59_754846_1 1123261.AXDW01000002_gene1560 1.43e-07 53.1 COG4773@1|root,COG4773@2|Bacteria,1MW5E@1224|Proteobacteria,1RMBD@1236|Gammaproteobacteria,1X3NJ@135614|Xanthomonadales 135614|Xanthomonadales P TonB-dependent siderophore receptor - - - ko:K16088 - - - - ko00000,ko02000 1.B.14.1.10,1.B.14.1.3,1.B.14.1.8 - - Plug,TonB_dep_Rec k59_258729_2 745411.B3C1_10677 1.64e-69 214.0 COG0454@1|root,COG0456@2|Bacteria,1RHUD@1224|Proteobacteria,1S540@1236|Gammaproteobacteria 1236|Gammaproteobacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 k59_158654_1 1123257.AUFV01000002_gene2587 1.16e-21 95.1 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,1RPZI@1236|Gammaproteobacteria,1X5ZA@135614|Xanthomonadales 135614|Xanthomonadales N Required for flagellar hook formation. May act as a scaffolding protein flgD - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig k59_904991_1 104623.Ser39006_01727 1.19e-79 264.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,40003@613|Serratia 1236|Gammaproteobacteria U Efflux pump membrane transporter acrB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006855,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015238,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015307,GO:0015318,GO:0015672,GO:0015893,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1902495,GO:1902600,GO:1990281,GO:1990351 - ko:K18138,ko:K18142 ko01501,ko01503,map01501,map01503 M00647,M00696,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - iAF1260.b3266,iJO1366.b3266,iZ_1308.Z4627 ACR_tran k59_704926_1 62928.azo3445 6.79e-106 314.0 COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,2VIID@28216|Betaproteobacteria,2KVZ8@206389|Rhodocyclales 206389|Rhodocyclales U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k59_258744_1 202954.BBNK01000003_gene2424 0.000131 44.7 COG4540@1|root,COG4540@2|Bacteria,1N2WK@1224|Proteobacteria,1RRER@1236|Gammaproteobacteria,3NKA5@468|Moraxellaceae 1236|Gammaproteobacteria S Type VI secretion system, phage-baseplate injector V - - - - - - - - - - - Phage_base_V k59_258744_2 292414.TM1040_1292 1.25e-29 109.0 COG3628@1|root,COG3628@2|Bacteria,1N7WS@1224|Proteobacteria,2V52H@28211|Alphaproteobacteria,4NDJQ@97050|Ruegeria 28211|Alphaproteobacteria S Gene 25-like lysozyme - - - ko:K06903 - - - - ko00000 - - - GPW_gp25 k59_258744_3 29252.Q37840_BP186 2.97e-41 147.0 4QAMU@10239|Viruses,4QV4U@35237|dsDNA viruses no RNA stage,4QPEV@28883|Caudovirales,4QI0J@10662|Myoviridae 10662|Myoviridae S Baseplate J-like protein - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098025 - - - - - - - - - - - k59_1359504_1 666685.R2APBS1_2977 2.68e-73 238.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3YM@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis protein cheA2 - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt k59_1055278_1 477228.YO5_18642 6.15e-94 285.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1Z1D6@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Oxidative deamination of D-amino acids dadA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0008718,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009324,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019478,GO:0019480,GO:0019752,GO:0032991,GO:0042851,GO:0042853,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055114,GO:0055130,GO:0071704,GO:0071944,GO:0098796,GO:0098797,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_1883,iSFV_1184.SFV_1196,iSF_1195.SF1178,iSFxv_1172.SFxv_1352,iS_1188.S1266,iUMNK88_1353.UMNK88_1502,iYL1228.KPN_02309 DAO k59_1055278_2 1523503.JPMY01000004_gene1581 1.98e-33 117.0 COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,1S5WM@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Translation Initiation Inhibitor YjgF Family IV02_05570 - - - - - - - - - - - Ribonuc_L-PSP k59_1559649_1 1123236.KB899376_gene508 8.75e-44 155.0 COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria,467FY@72275|Alteromonadaceae 1236|Gammaproteobacteria L Integrase core domain - - - - - - - - - - - - HTH_38,rve k59_172674_1 744980.TRICHSKD4_0365 1.08e-41 144.0 COG4665@1|root,COG4665@2|Bacteria,1QV7S@1224|Proteobacteria,2TWCP@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ k59_172674_2 1207063.P24_07236 2.31e-17 81.3 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria,2JQSH@204441|Rhodospirillales 204441|Rhodospirillales G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM k59_1573719_1 272123.Anacy_1700 1.78e-34 132.0 28P53@1|root,2ZC07@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_1414725_1 930166.CD58_09760 4.94e-76 240.0 COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,1RMSI@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k59_1414725_2 1499686.BN1079_00087 2.97e-14 71.2 COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,1RPU1@1236|Gammaproteobacteria 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB k59_14507_1 1268068.PG5_54120 3.97e-38 144.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,MHYT k59_222946_1 94624.Bpet1519 3.45e-50 166.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHCD@28216|Betaproteobacteria,3T38E@506|Alcaligenaceae 28216|Betaproteobacteria O Belongs to the GST superfamily - - 2.5.1.18 ko:K00799,ko:K11209 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 k59_813292_1 699246.HMPREF0868_0178 2.22e-12 70.5 COG1253@1|root,COG3064@1|root,COG1253@2|Bacteria,COG3064@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,267YU@186813|unclassified Clostridiales 186801|Clostridia M Psort location CytoplasmicMembrane, score - - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 k59_813292_2 436308.Nmar_1009 4.73e-19 87.0 arCOG10568@1|root,arCOG10568@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_14567_1 1163408.UU9_08917 5.58e-109 343.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1X3S8@135614|Xanthomonadales 135614|Xanthomonadales E Aminopeptidase N pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 k59_1313233_1 1234364.AMSF01000027_gene3475 1.33e-66 216.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,1X2Y9@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD k59_223081_1 1500890.JQNL01000001_gene2579 2.45e-102 320.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,1X3TQ@135614|Xanthomonadales 135614|Xanthomonadales M aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 k59_1414914_1 243277.VC_2229 4.52e-43 151.0 COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,1RNEK@1236|Gammaproteobacteria,1XTCN@135623|Vibrionales 135623|Vibrionales S glutamine amidotransferase yafJ - - - - - - - - - - - GATase_4 k59_1374109_1 766499.C357_03665 2.77e-09 59.7 COG3090@1|root,COG3090@2|Bacteria,1NCEM@1224|Proteobacteria,2UFJP@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - - - - - - - - - - DctQ k59_412968_1 436308.Nmar_1717 5.12e-50 168.0 COG0704@1|root,arCOG00318@2157|Archaea,41T1H@651137|Thaumarchaeota 651137|Thaumarchaeota P Phosphate uptake regulator - - - - - - - - - - - - PhoU k59_412968_2 1229909.NSED_09140 9.24e-40 133.0 COG0494@1|root,arCOG01073@2157|Archaea,41T73@651137|Thaumarchaeota 651137|Thaumarchaeota L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX k59_464482_1 426117.M446_1905 1.75e-06 54.7 COG2267@1|root,COG2267@2|Bacteria,1MW9H@1224|Proteobacteria,2U1YC@28211|Alphaproteobacteria,1JRVA@119045|Methylobacteriaceae 28211|Alphaproteobacteria I PFAM alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k59_1313361_1 1234364.AMSF01000055_gene1106 3.25e-46 165.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales 135614|Xanthomonadales T Chemotaxis protein histidine kinase and related kinases pilL - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k59_1313361_2 1234364.AMSF01000055_gene1107 8.35e-25 103.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X5CR@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis protein pilJ - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ k59_273384_1 666685.R2APBS1_0294 4.62e-38 135.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1X4QH@135614|Xanthomonadales 135614|Xanthomonadales O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 k59_273384_2 1234364.AMSF01000085_gene2961 1.73e-38 129.0 COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,1X7FD@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 k59_763021_1 666685.R2APBS1_3635 3.68e-08 53.9 COG0737@1|root,COG0737@2|Bacteria,1MU11@1224|Proteobacteria,1RMQV@1236|Gammaproteobacteria,1X53A@135614|Xanthomonadales 135614|Xanthomonadales F Belongs to the 5'-nucleotidase family - - 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 - R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos k59_1574276_1 1500893.JQNB01000001_gene1260 4.55e-104 316.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1X34C@135614|Xanthomonadales 135614|Xanthomonadales C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k59_913294_2 1500894.JQNN01000001_gene1765 3.97e-44 150.0 COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,2VIMK@28216|Betaproteobacteria,477AG@75682|Oxalobacteraceae 28216|Betaproteobacteria Q Isochorismatase family pncA - 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 - R01268 RC00100 ko00000,ko00001,ko01000 - - - Isochorismatase k59_1313476_1 1163407.UU7_13668 3.86e-127 373.0 COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,1RNFI@1236|Gammaproteobacteria,1X54A@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the peptidase M17 family pepA2 - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17 k59_614705_1 999541.bgla_2g07730 7.93e-86 263.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2VKTZ@28216|Betaproteobacteria,1K02I@119060|Burkholderiaceae 28216|Betaproteobacteria P transporter - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 k59_1215245_1 1151116.Q7S_04895 4.05e-107 324.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,3FF6D@34037|Rahnella 1236|Gammaproteobacteria E GMC oxidoreductase - - 1.1.5.9 ko:K19813 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R00305 RC00066 ko00000,ko00001,ko01000 - - - DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8 k59_1465116_1 1500894.JQNN01000001_gene41 0.000102 50.4 COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VQQQ@28216|Betaproteobacteria,47621@75682|Oxalobacteraceae 28216|Betaproteobacteria N Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end fliDL - - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliD_C,FliD_N k59_1114038_1 1448139.AI20_17980 1.35e-27 107.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1Y3T2@135624|Aeromonadales 135624|Aeromonadales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k59_1114038_2 380703.AHA_0295 1.51e-95 279.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1Y4BM@135624|Aeromonadales 135624|Aeromonadales U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB - - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB k59_873875_1 666685.R2APBS1_0529 6.51e-39 140.0 COG0508@1|root,COG0508@2|Bacteria,1MVDC@1224|Proteobacteria,1RQ9Y@1236|Gammaproteobacteria,1X3QW@135614|Xanthomonadales 135614|Xanthomonadales C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding k59_873875_2 666685.R2APBS1_0530 1.47e-116 340.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,1RP3G@1236|Gammaproteobacteria,1X44Z@135614|Xanthomonadales 135614|Xanthomonadales C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C k59_763201_1 287.DR97_4987 7.34e-46 154.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,1YCRD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Electron transfer flavoprotein domain etfB - - ko:K03521 - - - - ko00000 - - - ETF k59_362698_2 436308.Nmar_0705 4.11e-11 65.9 COG1378@1|root,arCOG02037@2157|Archaea,41T5N@651137|Thaumarchaeota 651137|Thaumarchaeota K transcriptional - - - - - - - - - - - - TrmB k59_1063887_1 1469245.JFBG01000011_gene855 3.79e-109 332.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1WW8W@135613|Chromatiales 135613|Chromatiales I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k59_1263921_1 1149133.ppKF707_3869 3.74e-131 378.0 COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1YDA7@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria HJ Sugar-transfer associated ATP-grasp PA1766 - - - - - - - - - - - ATPgrasp_ST k59_464834_1 745411.B3C1_12319 5.28e-20 89.7 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1J56I@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T (GGDEF) domain - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_4,PAS_9,Reg_prop k59_513271_1 1123020.AUIE01000010_gene1227 1.35e-53 174.0 COG2834@1|root,COG2834@2|Bacteria,1RFBN@1224|Proteobacteria,1S7A5@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - - - - - - - - - - DUF1571 k59_513271_2 1123020.AUIE01000010_gene1226 2.99e-07 48.9 COG3794@1|root,COG3794@2|Bacteria,1N0BX@1224|Proteobacteria,1SFAN@1236|Gammaproteobacteria 1236|Gammaproteobacteria C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - Cupredoxin_1 k59_314771_1 1234364.AMSF01000063_gene2255 5.24e-112 342.0 COG4934@1|root,COG4934@2|Bacteria,1R55X@1224|Proteobacteria,1SFP4@1236|Gammaproteobacteria,1XC3H@135614|Xanthomonadales 135614|Xanthomonadales O Pro-kumamolisin, activation domain - - - - - - - - - - - - Pro-kuma_activ k59_1164053_1 1453503.AU05_16860 1.99e-27 110.0 COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,1RNX1@1236|Gammaproteobacteria,1YF5U@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria MU Outer membrane efflux protein aggA - - ko:K12543 - M00330 - - ko00000,ko00002,ko02000,ko02044 1.B.17,3.A.1.109.4 - - OEP,OmpA k59_563325_1 1452718.JBOY01000112_gene986 3.65e-145 416.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Arabinose 5-phosphate isomerase kdsD GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0019146,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046400,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECH74115_1262.ECH74115_4519,iECSP_1301.ECSP_4172,iECs_1301.ECs4076,iPC815.YPO3577,iSFV_1184.SFV_3227,iSFxv_1172.SFxv_3550,iYL1228.KPN_03607,iZ_1308.Z4560 CBS,SIS k59_563325_2 1245471.PCA10_10330 2.96e-14 68.9 COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1YE2I@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate kdsC GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 ko:K03270 ko00540,ko01100,map00540,map01100 M00063 R03350 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - iECO26_1355.ECO26_4302 Hydrolase_3 k59_1465376_1 1229909.NSED_04540 8.91e-34 126.0 COG0161@1|root,arCOG00917@2157|Archaea,41S7K@651137|Thaumarchaeota 651137|Thaumarchaeota H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k59_1374983_1 498211.CJA_1314 2.25e-16 77.4 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1FGJH@10|Cellvibrio 1236|Gammaproteobacteria S ABC transporter yjjK GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 ko:K06020 - - - - ko00000,ko01000 - - - ABC_tran,ABC_tran_Xtn k59_1374983_2 95619.PM1_0205505 1.64e-51 173.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k59_1515296_1 1283300.ATXB01000001_gene493 4.04e-38 144.0 COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,1RR35@1236|Gammaproteobacteria 1236|Gammaproteobacteria P TrkA-N domain - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N k59_814018_1 316273.XCV0996 1.05e-235 652.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1X48A@135614|Xanthomonadales 135614|Xanthomonadales J GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 k59_874397_1 767434.Fraau_1346 3.08e-174 517.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1X3MZ@135614|Xanthomonadales 135614|Xanthomonadales F Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k59_224144_1 1283300.ATXB01000002_gene3017 7.44e-34 123.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1XDUJ@135618|Methylococcales 135618|Methylococcales H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k59_224144_2 243233.MCA1233 6.38e-31 115.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1XETJ@135618|Methylococcales 135618|Methylococcales F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_1261543_1 1163407.UU7_12451 4.67e-110 340.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1X2ZU@135614|Xanthomonadales 135614|Xanthomonadales L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 k59_1212770_1 1469613.JT55_15170 6.21e-32 122.0 COG1335@1|root,COG1335@2|Bacteria,1R86Z@1224|Proteobacteria,2U7GN@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q hydrolase - - - - - - - - - - - - Isochorismatase k59_61118_1 767434.Fraau_1192 1.98e-20 89.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1X4R7@135614|Xanthomonadales 135614|Xanthomonadales E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT k59_61118_2 1234364.AMSF01000039_gene6 2.81e-65 208.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1X472@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k59_1011526_1 1163407.UU7_09850 1.47e-60 202.0 COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,1RPK4@1236|Gammaproteobacteria,1X4C2@135614|Xanthomonadales 135614|Xanthomonadales S type VI secretion protein - - - ko:K11896 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - T6SS_TssF k59_1011526_2 1234364.AMSF01000056_gene1201 1.61e-27 108.0 COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,1RQD5@1236|Gammaproteobacteria,1XC6G@135614|Xanthomonadales 135614|Xanthomonadales S Type VI secretion, TssG - - - - - - - - - - - - T6SS_TssG k59_61150_1 225117.XP_009344368.1 2.31e-07 55.5 COG0177@1|root,KOG1921@2759|Eukaryota,37PW5@33090|Viridiplantae,3G87F@35493|Streptophyta,4JDYP@91835|fabids 35493|Streptophyta L Bifunctional DNA N-glycosylase with associated apurinic apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N- glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines NTH1 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005911,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009295,GO:0009506,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0012505,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0016787,GO:0016798,GO:0016799,GO:0018022,GO:0018193,GO:0018205,GO:0019104,GO:0019538,GO:0030054,GO:0032259,GO:0033554,GO:0033683,GO:0034641,GO:0036211,GO:0042644,GO:0042646,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055044,GO:0071704,GO:0090304,GO:0090305,GO:0140096,GO:0140097,GO:1901360,GO:1901564 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD k59_870543_2 639030.JHVA01000001_gene2056 3.18e-14 76.6 COG0815@1|root,COG0815@2|Bacteria,3Y4TQ@57723|Acidobacteria,2JKAE@204432|Acidobacteriia 204432|Acidobacteriia M Carbon-nitrogen hydrolase - - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase k59_511118_2 436308.Nmar_0749 2.91e-36 130.0 arCOG10540@1|root,arCOG10540@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_1413054_1 1229909.NSED_00610 3.32e-55 172.0 COG1631@1|root,arCOG04109@2157|Archaea,41SQZ@651137|Thaumarchaeota 651137|Thaumarchaeota J Binds to the 23S rRNA rpl44e - - ko:K02929 ko03010,map03010 M00177,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L44 k59_1413054_2 436308.Nmar_1580 1.12e-29 105.0 COG2051@1|root,arCOG04108@2157|Archaea,41SUD@651137|Thaumarchaeota 651137|Thaumarchaeota J ribosomal protein rps27e - - ko:K02978 ko03010,map03010 M00177,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S27e k59_1111861_1 1123269.NX02_12660 1.01e-20 94.4 COG4774@1|root,COG4774@2|Bacteria,1PIT1@1224|Proteobacteria,2TR52@28211|Alphaproteobacteria,2K2XI@204457|Sphingomonadales 204457|Sphingomonadales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_1571206_1 1163409.UUA_10646 2.64e-28 107.0 COG1999@1|root,COG1999@2|Bacteria,1N6R6@1224|Proteobacteria,1SI8Q@1236|Gammaproteobacteria,1X6MT@135614|Xanthomonadales 135614|Xanthomonadales S signal sequence binding - - - - - - - - - - - - - k59_1571206_2 1163409.UUA_10641 1.08e-45 157.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1X432@135614|Xanthomonadales 135614|Xanthomonadales O cytochrome oxidase assembly - - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA k59_711379_1 666685.R2APBS1_0833 6.49e-112 347.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1X2YZ@135614|Xanthomonadales 135614|Xanthomonadales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 k59_12858_2 382245.ASA_0710 5.65e-73 224.0 COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,1RR95@1236|Gammaproteobacteria,1Y49Z@135624|Aeromonadales 135624|Aeromonadales C Oxidoreductase NAD-binding domain - - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - FAD_binding_6,NAD_binding_1 k59_961845_1 666685.R2APBS1_3855 7.51e-97 297.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1X30N@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d k59_811610_2 1439940.BAY1663_01242 1.12e-43 143.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Cold shock CH92_15505 - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k59_270406_1 1227739.Hsw_0565 7.82e-12 71.2 COG3291@1|root,COG4625@1|root,COG3291@2|Bacteria,COG4625@2|Bacteria,4NDZC@976|Bacteroidetes,47YR2@768503|Cytophagia 976|Bacteroidetes S Pkd domain containing protein - - - - - - - - - - - - CHU_C,DUF11,SprB k59_1122264_1 757424.Hsero_0745 2.03e-74 241.0 COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,2VHXS@28216|Betaproteobacteria,473QW@75682|Oxalobacteraceae 28216|Betaproteobacteria S type VI secretion protein - - - ko:K11896 - M00334 - - ko00000,ko00002,ko02044 3.A.23.1 - - T6SS_TssF k59_1522625_1 1283300.ATXB01000002_gene2890 2.08e-62 206.0 COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria 1236|Gammaproteobacteria C ATP ADP translocase - - - ko:K03301 - - - - ko00000 2.A.12 - - MFS_1,TLC k59_670879_1 1896.JOAU01000008_gene6093 0.00016 47.4 COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria 201174|Actinobacteria L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta k59_1020899_1 1229909.NSED_09455 8.55e-46 158.0 COG0484@1|root,arCOG02846@2157|Archaea,41T1F@651137|Thaumarchaeota 651137|Thaumarchaeota O DnaJ molecular chaperone homology domain - - - - - - - - - - - - DnaJ k59_1386204_1 1121015.N789_13365 3.61e-07 48.1 COG2841@1|root,COG2841@2|Bacteria 2|Bacteria S Protein of unknown function (DUF465) VPA0402 - - ko:K09794 - - - - ko00000 - - - DUF465 k59_1386204_2 1163409.UUA_11693 2.08e-120 355.0 COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1X4GC@135614|Xanthomonadales 135614|Xanthomonadales E Cystathionine beta-synthase cysB - 4.2.1.22 ko:K01697 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP k59_22829_1 1500890.JQNL01000001_gene214 7.22e-137 409.0 COG4773@1|root,COG4773@2|Bacteria,1MW5E@1224|Proteobacteria,1RMBD@1236|Gammaproteobacteria,1X3NJ@135614|Xanthomonadales 135614|Xanthomonadales P TonB-dependent siderophore receptor - - - ko:K16088 - - - - ko00000,ko02000 1.B.14.1.10,1.B.14.1.3,1.B.14.1.8 - - Plug,TonB_dep_Rec k59_1522813_1 316067.Geob_3081 2.68e-34 127.0 COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales 28221|Deltaproteobacteria M Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue pilD - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 k59_1586499_1 765910.MARPU_16150 4.11e-20 82.4 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1WYPW@135613|Chromatiales 135613|Chromatiales K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 k59_1586499_2 1117318.PRUB_04536 8.27e-19 84.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,2Q1CR@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_2813,iPC815.YPO0040,iSBO_1134.SBO_3729,iSFV_1184.SFV_3881,iSFxv_1172.SFxv_4016,iUTI89_1310.UTI89_C4193 Guanylate_kin k59_771185_2 459495.SPLC1_S202510 1.92e-56 187.0 COG0754@1|root,COG0754@2|Bacteria,1G4ND@1117|Cyanobacteria,1H9K0@1150|Oscillatoriales 1117|Cyanobacteria E Glutathionylspermidine synthase - - - - - - - - - - - - GSP_synth k59_720904_1 1122194.AUHU01000006_gene516 1.51e-58 201.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,4654W@72275|Alteromonadaceae 1236|Gammaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N k59_571158_1 1500893.JQNB01000001_gene1894 4.14e-72 239.0 COG4774@1|root,COG4774@2|Bacteria,1QU2Y@1224|Proteobacteria,1T1NS@1236|Gammaproteobacteria,1X4WK@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_367957_1 1268237.G114_03793 5.98e-28 108.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1Y3R3@135624|Aeromonadales 135624|Aeromonadales T PhoH-like protein - - - ko:K06217 - - - - ko00000 - - - PhoH k59_367957_2 380703.AHA_3241 1.42e-56 188.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1Y3KP@135624|Aeromonadales 135624|Aeromonadales J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k59_1071268_1 743299.Acife_2323 8.08e-76 240.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria 1236|Gammaproteobacteria L reverse transcriptase - - - - - - - - - - - - GIIM,RVT_1 k59_1224708_1 301.JNHE01000003_gene1914 3.56e-112 336.0 COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,1YDTD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Belongs to the glutamate synthase family HA62_33250 - - - - - - - - - - - Glu_synthase k59_368057_1 666685.R2APBS1_0559 2.18e-93 284.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1X35T@135614|Xanthomonadales 135614|Xanthomonadales F Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK k59_368057_2 748224.HMPREF9436_01043 0.000135 43.9 COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,3WITI@541000|Ruminococcaceae 186801|Clostridia S Psort location Cytoplasmic, score nt5e - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k59_1473202_1 767434.Fraau_3037 6.6e-89 270.0 COG4638@1|root,COG4638@2|Bacteria,1MXXI@1224|Proteobacteria,1RRNX@1236|Gammaproteobacteria,1X5GW@135614|Xanthomonadales 135614|Xanthomonadales P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske k59_921651_1 1388763.O165_019780 3.32e-53 182.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1YV3J@136845|Pseudomonas putida group 1236|Gammaproteobacteria O Heat shock 70 kDa protein dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k59_921651_2 1245471.PCA10_49280 4.83e-18 79.3 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1YEVP@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE k59_368115_1 983917.RGE_17920 4.64e-95 303.0 COG4103@1|root,COG4103@2|Bacteria,1MURD@1224|Proteobacteria,2VIYZ@28216|Betaproteobacteria,1KN81@119065|unclassified Burkholderiales 28216|Betaproteobacteria S TerB-C domain - - - - - - - - - - - - TerB,TerB_C,TerB_N k59_1421260_1 331869.BAL199_27166 3.06e-63 204.0 COG0596@1|root,COG0596@2|Bacteria,1NJ2B@1224|Proteobacteria,2TR54@28211|Alphaproteobacteria 28211|Alphaproteobacteria S alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1 k59_421211_1 1234364.AMSF01000095_gene2522 7.85e-41 148.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,1RQ7G@1236|Gammaproteobacteria,1X4ES@135614|Xanthomonadales 135614|Xanthomonadales J glutaminyl-tRNA synthetase glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C k59_421211_2 1234364.AMSF01000095_gene2523 4.8e-53 171.0 COG0590@1|root,COG0590@2|Bacteria,1N2FE@1224|Proteobacteria,1S35R@1236|Gammaproteobacteria,1X5NY@135614|Xanthomonadales 135614|Xanthomonadales FJ Cytidine and deoxycytidylate deaminase zinc-binding region - - - - - - - - - - - - dCMP_cyt_deam_1 k59_624284_1 1349767.GJA_2556 0.000755 46.6 COG3157@1|root,COG3157@2|Bacteria,1R3V8@1224|Proteobacteria,2VP81@28216|Betaproteobacteria,472J8@75682|Oxalobacteraceae 28216|Betaproteobacteria S Type VI secretion system effector, Hcp - - - ko:K11903 ko02025,ko03070,map02025,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 - - - T6SS_HCP k59_721344_1 1111134.HMPREF1253_1148 4.78e-05 45.1 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,2489I@186801|Clostridia,22GUS@1570339|Peptoniphilaceae 186801|Clostridia O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran k59_721344_2 1229909.NSED_02590 1.45e-23 91.3 COG1872@1|root,arCOG04058@2157|Archaea,41TAX@651137|Thaumarchaeota 651137|Thaumarchaeota S DUF167 - - - ko:K09131 - - - - ko00000 - - - DUF167 k59_721344_3 1131266.ARWQ01000005_gene828 9.68e-27 103.0 COG3253@1|root,arCOG03031@2157|Archaea,41SGX@651137|Thaumarchaeota 651137|Thaumarchaeota S Chlorite dismutase - - - - - - - - - - - - Chlor_dismutase k59_474317_1 1234364.AMSF01000068_gene2147 1.66e-99 305.0 COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1X48N@135614|Xanthomonadales 135614|Xanthomonadales Q MlaD protein - - - ko:K06192 - - - - ko00000 - - - MlaD k59_368271_1 1123020.AUIE01000035_gene5283 4.8e-53 181.0 COG3391@1|root,COG3391@2|Bacteria,1R8X0@1224|Proteobacteria,1S1R2@1236|Gammaproteobacteria,1YFM8@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Methylamine dehydrogenase heavy chain (MADH) - - 1.4.9.1 ko:K15229 ko00680,ko01120,map00680,map01120 - R00606 RC00189 ko00000,ko00001,ko01000 - - - Me-amine-dh_H k59_1523390_1 1500893.JQNB01000001_gene646 3.46e-66 220.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1X3B9@135614|Xanthomonadales 135614|Xanthomonadales K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind k59_1171736_1 686578.AFFX01000003_gene87 3.38e-31 118.0 COG2199@1|root,COG3706@2|Bacteria,1MV4X@1224|Proteobacteria,1S5A8@1236|Gammaproteobacteria 1236|Gammaproteobacteria T GGDEF domain - - 2.7.7.65 ko:K21020 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - GGDEF k59_1171736_2 287.DR97_3126 7.51e-40 134.0 2AD7J@1|root,312WH@2|Bacteria,1RHF8@1224|Proteobacteria,1S9YU@1236|Gammaproteobacteria,1YJGU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Domain of unknown function (DUF1987) - - - - - - - - - - - - DUF1987 k59_1225103_1 1301098.PKB_0800 4.38e-68 218.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k59_1071672_1 1149133.ppKF707_4797 8.91e-44 152.0 COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1S02J@1236|Gammaproteobacteria,1YHCN@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P Ring hydroxylating alpha subunit (catalytic domain) - - 1.14.15.7 ko:K00499 ko00260,map00260 - R07409 RC00087 ko00000,ko00001,ko01000 - - - Rieske,Ring_hydroxyl_A k59_822777_1 748247.AZKH_0311 1.43e-82 249.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,2KW4C@206389|Rhodocyclales 206389|Rhodocyclales U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB k59_822777_2 748247.AZKH_0312 1.24e-12 66.2 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,2KV1K@206389|Rhodocyclales 206389|Rhodocyclales U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm k59_969168_1 1234364.AMSF01000010_gene609 8.62e-131 379.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,1X3NN@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 k59_1587407_1 383407.XOC_4633 9.88e-19 82.8 COG2913@1|root,COG2913@2|Bacteria,1RDAX@1224|Proteobacteria,1SIDU@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - - k59_624575_1 876044.IMCC3088_2193 8.41e-40 132.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,1J6PJ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 k59_624575_2 55601.VANGNB10_cI2548c 8.37e-25 98.2 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1XTU6@135623|Vibrionales 135623|Vibrionales E Belongs to the UPF0758 family radC GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03630 - - - - ko00000 - - - RadC k59_474580_2 1278309.KB907104_gene976 1.4e-15 73.6 COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria,1XKKS@135619|Oceanospirillales 135619|Oceanospirillales S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit k59_571840_1 1245471.PCA10_32780 2.14e-111 339.0 COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1MWD4@1224|Proteobacteria,1RVX0@1236|Gammaproteobacteria,1YEIH@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria CI MaoC like domain paaN GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016725,GO:0016726,GO:0016787,GO:0016801,GO:0016803,GO:0016822,GO:0016823,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.2.1.91,3.3.2.12 ko:K02618 ko00360,ko01120,map00360,map01120 - R09820,R09836 RC00080,RC02667 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_1523,iECO111_1330.ECO111_1781,iECO26_1355.ECO26_1991 Aldedh,MaoC_dehydratas k59_624747_1 1163409.UUA_13540 1.69e-21 87.4 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,1X7J1@135614|Xanthomonadales 135614|Xanthomonadales U Preprotein translocase subunit YajC yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC k59_624747_2 1500893.JQNB01000001_gene209 1.4e-36 132.0 COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,1X46Q@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT k59_1273136_1 1234364.AMSF01000010_gene581 1.78e-99 301.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1X3GF@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DUF1508,tRNA-synt_1b k59_23783_1 1055815.AYYA01000030_gene760 1.16e-32 124.0 COG0697@1|root,COG0697@2|Bacteria,1MV7Y@1224|Proteobacteria,1RMVI@1236|Gammaproteobacteria 1236|Gammaproteobacteria EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA k59_969397_1 436308.Nmar_1399 5.08e-57 198.0 arCOG08705@1|root,arCOG08705@2157|Archaea,41SXV@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_1387656_1 1234364.AMSF01000053_gene1298 7.03e-77 243.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1X306@135614|Xanthomonadales 135614|Xanthomonadales MU TIGRFAM type I secretion outer membrane protein, TolC family raxC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k59_137212_1 1234364.AMSF01000095_gene2586 2.74e-72 229.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,1X46N@135614|Xanthomonadales 135614|Xanthomonadales S permease - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ k59_572100_1 1234364.AMSF01000088_gene2767 1.69e-106 322.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1X4ZP@135614|Xanthomonadales 135614|Xanthomonadales IQ AMP-binding enzyme C-terminal domain - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k59_1072156_1 1234364.AMSF01000003_gene2419 5.49e-98 308.0 COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,1RMA0@1236|Gammaproteobacteria,1X4AX@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the glycosyl hydrolase 3 family - - - - - - - - - - - - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C k59_922416_1 517417.Cpar_0315 0.000166 47.4 COG5295@1|root,COG5295@2|Bacteria 2|Bacteria UW Hep Hag repeat protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Beta_helix,ESPR,Haemagg_act,YadA_anchor,YadA_head,YadA_stalk k59_23945_1 1453503.AU05_05810 2.08e-75 232.0 COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,1RM8F@1236|Gammaproteobacteria,1YDU0@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S ABC transporter urtD - - ko:K11962 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran,BCA_ABC_TP_C k59_23945_2 399739.Pmen_0697 9.62e-57 181.0 COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,1RMEM@1236|Gammaproteobacteria,1YEIM@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E ATPases associated with a variety of cellular activities urtE - - ko:K11963 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran k59_23945_3 323848.Nmul_A2070 7.39e-10 58.5 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2VQ2F@28216|Betaproteobacteria,372WR@32003|Nitrosomonadales 28216|Betaproteobacteria F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin k59_237037_1 745411.B3C1_10332 1.25e-53 177.0 COG0671@1|root,COG0671@2|Bacteria,1MWW4@1224|Proteobacteria,1RNSB@1236|Gammaproteobacteria,1JB1J@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Acid phosphatase homologues pgpB GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019637,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0034645,GO:0042546,GO:0042578,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044425,GO:0044459,GO:0044462,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0050380,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_1403,iECUMN_1333.ECUMN_1580 PAP2 k59_474947_1 1229909.NSED_00085 1.27e-93 276.0 COG2109@1|root,arCOG04678@2157|Archaea,41SFP@651137|Thaumarchaeota 651137|Thaumarchaeota H ATP corrinoid adenosyltransferase - - 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - CobA_CobO_BtuR k59_1289911_1 330214.NIDE0488 6.15e-85 263.0 COG0019@1|root,COG0019@2|Bacteria,3J0CR@40117|Nitrospirae 40117|Nitrospirae E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k59_342958_1 1245471.PCA10_17710 1e-73 225.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RYYJ@1236|Gammaproteobacteria,1YE2Z@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K Transcriptional regulatory protein IV02_20810 - - - - - - - - - - - Transcrip_reg k59_342958_2 322710.Avin_18230 4.93e-17 74.3 2DYTZ@1|root,34B3C@2|Bacteria,1P20A@1224|Proteobacteria,1SSVR@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_738234_1 1123368.AUIS01000001_gene1893 5.53e-74 239.0 COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,2NCDF@225057|Acidithiobacillales 225057|Acidithiobacillales L RQC - - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind k59_1140560_1 1234364.AMSF01000033_gene350 4.25e-73 233.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,1RMWX@1236|Gammaproteobacteria,1X2YC@135614|Xanthomonadales 135614|Xanthomonadales N Flagellar hook protein FlgE flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C k59_643551_1 1229909.NSED_02545 8.4e-70 216.0 COG1418@1|root,arCOG01860@2157|Archaea,41T2N@651137|Thaumarchaeota 651137|Thaumarchaeota S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K06950 - - - - ko00000 - - - HD k59_493604_1 1499686.BN1079_00995 2.2e-100 307.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria 1236|Gammaproteobacteria J L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iSFV_1184.SFV_1868 GAD,tRNA-synt_2,tRNA_anti-codon k59_493604_2 1523503.JPMY01000041_gene511 2.33e-53 173.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - - - - - - - - - - Transcrip_reg k59_839999_1 1234364.AMSF01000010_gene608 9e-151 443.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1X498@135614|Xanthomonadales 135614|Xanthomonadales G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tktA - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N k59_1290070_1 1121004.ATVC01000087_gene307 2.69e-14 71.6 COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2VHWS@28216|Betaproteobacteria,2KQMU@206351|Neisseriales 206351|Neisseriales C Phosphoenolpyruvate phosphomutase - - 4.1.3.1 ko:K01637 ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200 M00012 R00479 RC00311,RC00313 ko00000,ko00001,ko00002,ko01000 - - - ICL k59_1290070_2 391735.Veis_2191 5.53e-18 83.2 COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,4AAV9@80864|Comamonadaceae 28216|Betaproteobacteria M Peptidoglycan polymerase that is essential for cell wall elongation mrdB - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE k59_840070_1 1395571.TMS3_0115475 1.39e-98 296.0 COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,1S7P2@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k59_343195_1 1229909.NSED_09905 6.9e-87 275.0 COG1293@1|root,arCOG01695@2157|Archaea,41SB0@651137|Thaumarchaeota 651137|Thaumarchaeota K Fibronectin-binding protein A N-terminus (FbpA) - - - - - - - - - - - - DUF814,FbpA k59_788685_1 330214.NIDE0862 1.13e-31 121.0 COG0775@1|root,COG0775@2|Bacteria 2|Bacteria F adenosylhomocysteine nucleosidase activity MA20_16045 - 1.17.7.4,3.2.2.9 ko:K01243,ko:K03527 ko00270,ko00900,ko01100,ko01110,ko01130,ko01230,map00270,map00900,map01100,map01110,map01130,map01230 M00034,M00096,M00609 R00194,R01401,R05884,R08210 RC00063,RC00318,RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 k59_1438575_1 1229909.NSED_09335 8.92e-122 363.0 arCOG08764@1|root,arCOG08764@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_539652_1 1163408.UU9_11295 1.59e-127 369.0 COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,1RPQ8@1236|Gammaproteobacteria,1X30S@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the iron ascorbate-dependent oxidoreductase family - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N k59_539687_1 1121468.AUBR01000008_gene2048 3.04e-33 120.0 COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,42GZU@68295|Thermoanaerobacterales 186801|Clostridia S THIoesterase - - 3.1.2.29 ko:K18700 - - - - ko00000,ko01000 - - - 4HBT k59_689756_1 1453503.AU05_05025 3.3e-71 219.0 COG3038@1|root,COG3038@2|Bacteria,1RBP8@1224|Proteobacteria,1S563@1236|Gammaproteobacteria,1YFW3@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Prokaryotic cytochrome b561 yodB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB k59_1490200_1 1234364.AMSF01000005_gene759 7.23e-135 393.0 COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,1X3IZ@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 k59_162360_1 1499686.BN1079_01532 3.76e-98 309.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria 1236|Gammaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - iECW_1372.ECW_m2935,iWFL_1372.ECW_m2935 MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V k59_212506_1 1163409.UUA_13300 2.31e-88 281.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1N4G0@1224|Proteobacteria,1RRIM@1236|Gammaproteobacteria,1X37H@135614|Xanthomonadales 135614|Xanthomonadales EU peptidase - - - - - - - - - - - - DPPIV_N,PD40,Peptidase_S9 k59_162374_1 991905.SL003B_0641 1.08e-97 301.0 COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2TQKF@28211|Alphaproteobacteria,4BR8J@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria L Integrase core domain istA - - - - - - - - - - - rve k59_212549_1 1234364.AMSF01000013_gene633 1.63e-117 353.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,1X5B4@135614|Xanthomonadales 135614|Xanthomonadales S M61 glycyl aminopeptidase - - - - - - - - - - - - PDZ_2,Peptidase_M61 k59_1363429_1 767434.Fraau_2330 5.56e-58 200.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,1X4FQ@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_1256952_1 1163407.UU7_15935 3.63e-95 292.0 COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,1X4WM@135614|Xanthomonadales 135614|Xanthomonadales V ABC-type antimicrobial peptide transport system, permease component - - - - - - - - - - - - FtsX,MacB_PCD k59_556735_1 1207063.P24_15539 1.14e-50 170.0 COG0589@1|root,COG0589@2|Bacteria,1RATR@1224|Proteobacteria,2U6UI@28211|Alphaproteobacteria,2JZR5@204441|Rhodospirillales 204441|Rhodospirillales T Universal stress protein family - - - - - - - - - - - - Usp k59_1563454_1 1234364.AMSF01000056_gene1220 5.76e-51 181.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MWVZ@1224|Proteobacteria,1RQBQ@1236|Gammaproteobacteria,1X4P3@135614|Xanthomonadales 135614|Xanthomonadales KLT serine threonine protein kinase - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - FGE-sulfatase,Pkinase k59_262682_1 1301098.PKB_3462 2.9e-74 236.0 COG0534@1|root,COG0534@2|Bacteria,1QTIW@1224|Proteobacteria,1RZ7Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Na driven multidrug efflux pump vcmH - - - - - - - - - - - MatE k59_212690_1 1453503.AU05_21425 9.37e-94 285.0 COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,1RPHR@1236|Gammaproteobacteria,1YENV@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Aminopeptidase I zinc metalloprotease (M18) apeB GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 ko:K01267 - - - - ko00000,ko01000,ko01002,ko04131 - - - Peptidase_M18 k59_212690_2 1523503.JPMY01000012_gene3356 2.65e-14 70.1 COG0560@1|root,COG0560@2|Bacteria,1MWTU@1224|Proteobacteria,1RZWU@1236|Gammaproteobacteria 1236|Gammaproteobacteria E HAD family hydrolase - - - - - - - - - - - - HAD k59_756874_1 1333998.M2A_2079 8e-101 300.0 COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,2U149@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MA20_16350 - - - - - - - - - - - adh_short_C2 k59_863045_1 1294143.H681_00305 7.35e-62 192.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase k59_863045_2 1283284.AZUK01000001_gene1698 1.07e-14 72.4 COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1Y45J@135624|Aeromonadales 135624|Aeromonadales J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N k59_706880_1 666685.R2APBS1_2655 9.1e-104 318.0 COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1X3HM@135614|Xanthomonadales 135614|Xanthomonadales O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 k59_1363581_1 1202532.FF52_02430 1.86e-63 206.0 COG1216@1|root,COG1216@2|Bacteria,4NK0K@976|Bacteroidetes,1I0UB@117743|Flavobacteriia,2NVQ1@237|Flavobacterium 976|Bacteroidetes S Psort location Cytoplasmic, score - - - - - - - - - - - - - k59_1563658_1 574966.KB898648_gene691 2.59e-24 99.4 COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,1S1AC@1236|Gammaproteobacteria,1XJFE@135619|Oceanospirillales 135619|Oceanospirillales P ABC transporter - - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 k59_1563658_2 649638.Trad_1908 9.28e-16 76.6 COG3638@1|root,COG3638@2|Bacteria,1WIEK@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran k59_706950_1 292.DM42_20 5.23e-41 143.0 COG2099@1|root,COG2099@2|Bacteria,1MW48@1224|Proteobacteria,2VR1K@28216|Betaproteobacteria,1K0PH@119060|Burkholderiaceae 28216|Betaproteobacteria H PFAM Precorrin-6x reductase CbiJ CobK cobK - 1.3.1.106,1.3.1.54 ko:K05895 ko00860,ko01100,map00860,map01100 - R05150,R05812 RC01280 ko00000,ko00001,ko01000 - - - CbiJ k59_706950_2 395019.Bmul_1564 1.86e-27 105.0 COG2875@1|root,COG2875@2|Bacteria,1MVYY@1224|Proteobacteria,2VHWE@28216|Betaproteobacteria,1K113@119060|Burkholderiaceae 28216|Betaproteobacteria H Precorrin-4 C(11)-methyltransferase cobM - 2.1.1.133,2.1.1.271 ko:K05936 ko00860,ko01100,map00860,map01100 - R05181,R05810 RC00003,RC01294,RC02049 ko00000,ko00001,ko01000 - - - TP_methylase k59_607420_1 666685.R2APBS1_0835 1.23e-122 358.0 COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1X4NV@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D k59_263059_1 425104.Ssed_3610 4.68e-10 60.5 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RS6U@1236|Gammaproteobacteria,2QDJ0@267890|Shewanellaceae 1236|Gammaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k59_263059_2 360910.BAV2111 9.5e-18 84.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,3T1IN@506|Alcaligenaceae 28216|Betaproteobacteria E Catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 k59_1307090_1 1229909.NSED_02115 3.47e-81 251.0 COG1503@1|root,arCOG01742@2157|Archaea 1229909.NSED_02115|- J Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA - - - ko:K03265 ko03015,map03015 - - - ko00000,ko00001,ko03012,ko03019 - - - - k59_757051_1 745411.B3C1_09173 5.27e-70 217.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,1RMJ2@1236|Gammaproteobacteria,1J4WA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria N Belongs to the flagella basal body rod proteins family flgG - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k59_757051_2 1279019.ARQK01000061_gene1828 1.09e-15 75.9 COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,1RNVX@1236|Gammaproteobacteria,1WWVR@135613|Chromatiales 135613|Chromatiales N TIGRFAM flagellar basal-body rod protein FlgF - - - ko:K02391 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C k59_113052_1 1229909.NSED_03505 1.93e-20 82.4 COG0425@1|root,arCOG02062@2157|Archaea,41SU5@651137|Thaumarchaeota 651137|Thaumarchaeota O redox protein, regulator of disulfide bond formation - - - - - - - - - - - - TusA k59_113052_2 436308.Nmar_0670 1.16e-72 226.0 COG0031@1|root,arCOG01430@2157|Archaea,41SYM@651137|Thaumarchaeota 651137|Thaumarchaeota E Cysteine synthase - - 2.5.1.47 ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03132,R03601,R04859 RC00020,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - - PALP k59_213179_1 1123072.AUDH01000013_gene1493 5.57e-27 115.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2JQ4H@204441|Rhodospirillales 204441|Rhodospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - EAL,GAF,GGDEF,PAS_8 k59_56831_1 1562701.BBOF01000087_gene646 2.19e-15 71.2 arCOG05874@1|root,2ZJ01@2|Bacteria,1N8VY@1224|Proteobacteria,2W4ZN@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_8366_1 887898.HMPREF0551_0941 1.25e-80 246.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,1K293@119060|Burkholderiaceae 28216|Betaproteobacteria M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep k59_656905_1 1234364.AMSF01000024_gene3796 5.63e-96 303.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1X499@135614|Xanthomonadales 135614|Xanthomonadales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k59_1208053_1 745411.B3C1_17032 1.36e-109 347.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1J5AR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L COG1643 HrpA-like helicases hrpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind k59_307545_1 1286631.X805_15320 6.39e-35 137.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,1KJAY@119065|unclassified Burkholderiales 28216|Betaproteobacteria NT chemotaxis protein - - - ko:K03406,ko:K05874 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,TarH k59_1408817_1 160492.XF_2479 7.65e-81 253.0 COG3500@1|root,COG3500@2|Bacteria,1MXT8@1224|Proteobacteria,1RMKC@1236|Gammaproteobacteria,1X51B@135614|Xanthomonadales 135614|Xanthomonadales S Gene D protein (GpD) - - - ko:K06905 - - - - ko00000 - - - Phage_GPD k59_1408817_2 702113.PP1Y_AT3661 0.000339 42.4 COG5004@1|root,COG5004@2|Bacteria,1Q9W3@1224|Proteobacteria,2UUI5@28211|Alphaproteobacteria,2K7X5@204457|Sphingomonadales 204457|Sphingomonadales S Phage Tail Protein X - - - - - - - - - - - - Phage_tail_X k59_1408817_3 391619.PGA1_c18230 3.26e-10 60.1 COG3499@1|root,COG3499@2|Bacteria,1MZJ7@1224|Proteobacteria,2UD4V@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG3499 Phage protein U gpU1 - - ko:K06906 - - - - ko00000 - - - Phage_P2_GpU k59_457736_1 1163617.SCD_n00212 1.53e-82 248.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria 28216|Betaproteobacteria K Belongs to the UPF0301 (AlgH) family algH - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k59_707307_1 520999.PROVALCAL_03720 1.82e-54 187.0 COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,1RRHJ@1236|Gammaproteobacteria,3Z78A@586|Providencia 1236|Gammaproteobacteria S SPFH Band 7 PHB domain protein - - - - - - - - - - - - Band_7 k59_707307_2 1215092.PA6_018_00460 9.92e-21 87.0 2A865@1|root,30X71@2|Bacteria,1RE6C@1224|Proteobacteria,1S2PT@1236|Gammaproteobacteria,1YDVP@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - DUF1449 k59_1364448_1 1234364.AMSF01000055_gene1019 9.73e-140 406.0 COG1611@1|root,COG1611@2|Bacteria,1MVQJ@1224|Proteobacteria,1RQHX@1236|Gammaproteobacteria,1X3RE@135614|Xanthomonadales 135614|Xanthomonadales S Rossmann fold nucleotide-binding protein - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DUF3412,DUF4478,Lysine_decarbox k59_263648_1 1234364.AMSF01000088_gene2759 1.21e-108 327.0 COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,1RQ67@1236|Gammaproteobacteria,1X4GP@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family mtrC - - ko:K07799 ko02020,map02020 M00648 - - ko00000,ko00001,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_D23 k59_707366_1 1163407.UU7_00877 4.82e-123 358.0 COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1X30C@135614|Xanthomonadales 135614|Xanthomonadales M NAD dependent epimerase dehydratase - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd k59_163644_1 1056512.D515_03769 1.47e-67 212.0 2CIFR@1|root,2Z835@2|Bacteria,1RK4J@1224|Proteobacteria,1RTV2@1236|Gammaproteobacteria,1XZH6@135623|Vibrionales 135623|Vibrionales S Protein of unknown function (DUF2589) - - - - - - - - - - - - DUF2589 k59_1107676_1 1229909.NSED_04840 5.35e-10 59.7 COG0365@1|root,arCOG01529@2157|Archaea,41SZA@651137|Thaumarchaeota 651137|Thaumarchaeota I Acetyl-coenzyme A synthetase N-terminus - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k59_1107676_2 1229909.NSED_04845 7.35e-20 83.2 arCOG10556@1|root,arCOG10556@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_1107676_3 1229909.NSED_04850 5.02e-26 105.0 COG0064@1|root,arCOG01718@2157|Archaea,41S9S@651137|Thaumarchaeota 651137|Thaumarchaeota J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey k59_307707_1 281687.CJA13042 2.39e-49 168.0 COG0084@1|root,KOG3020@2759|Eukaryota,38FZ5@33154|Opisthokonta,3BC10@33208|Metazoa,3CV6G@33213|Bilateria,40BP1@6231|Nematoda,1KUKU@119089|Chromadorea,40X3H@6236|Rhabditida 33208|Metazoa L TatD related DNase - GO:0000737,GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006309,GO:0006725,GO:0006807,GO:0006810,GO:0006897,GO:0006909,GO:0006915,GO:0006921,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009057,GO:0009987,GO:0012501,GO:0016043,GO:0016192,GO:0016787,GO:0016788,GO:0019439,GO:0022411,GO:0030262,GO:0034641,GO:0034655,GO:0043170,GO:0043277,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0051179,GO:0051234,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097194,GO:0098657,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k59_1364694_1 436308.Nmar_1727 6.99e-32 123.0 COG1782@1|root,arCOG00543@2157|Archaea,41T05@651137|Thaumarchaeota 651137|Thaumarchaeota S RNA-metabolising metallo-beta-lactamase - - - ko:K07041 - - - - ko00000 - - - Beta-Casp,KH_7,Lactamase_B_6,RMMBL k59_1364694_2 1229909.NSED_09200 2.21e-43 146.0 COG0638@1|root,arCOG00970@2157|Archaea,41T1N@651137|Thaumarchaeota 651137|Thaumarchaeota O Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation - - 3.4.25.1 ko:K03433 ko03050,map03050 M00342,M00343 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03051 - - - Proteasome k59_907632_1 666685.R2APBS1_0474 3.21e-96 295.0 COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1X48D@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N k59_213982_1 1185652.USDA257_c39680 3.53e-45 162.0 COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2TU2E@28211|Alphaproteobacteria,4B9N7@82115|Rhizobiaceae 28211|Alphaproteobacteria G Phosphoketolase - - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N k59_357427_1 998088.B565_0405 2.87e-56 189.0 COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1Y3HT@135624|Aeromonadales 135624|Aeromonadales H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP k59_357427_2 1448139.AI20_16555 4.96e-14 68.9 COG1802@1|root,COG1802@2|Bacteria,1RBC0@1224|Proteobacteria,1S35Z@1236|Gammaproteobacteria,1Y4VE@135624|Aeromonadales 135624|Aeromonadales K COG1802 Transcriptional regulators - - - - - - - - - - - - FCD,GntR k59_507094_1 682795.AciX8_3147 6.42e-126 381.0 28I74@1|root,2Z8A0@2|Bacteria,3Y3AF@57723|Acidobacteria,2JJ0M@204432|Acidobacteriia 204432|Acidobacteriia S COG NOG26804 non supervised orthologous group - - - - - - - - - - - - - k59_264075_1 745411.B3C1_07439 6.4e-107 313.0 2DBI4@1|root,2Z9EH@2|Bacteria,1MXNH@1224|Proteobacteria,1RT1Y@1236|Gammaproteobacteria,1J6JT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k59_1058109_1 1163408.UU9_02983 1.48e-68 226.0 COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1X4TB@135614|Xanthomonadales 135614|Xanthomonadales M (Lipo)protein - - - ko:K07121 - - - - ko00000 - - - LppC k59_608136_2 745411.B3C1_18612 5.77e-70 219.0 COG4972@1|root,COG4972@2|Bacteria 2|Bacteria NU Pilus assembly protein mshI - - ko:K12279 - - - - ko00000,ko02044 - - - - k59_657282_1 1500259.JQLD01000012_gene5345 1.35e-63 211.0 COG3119@1|root,COG3119@2|Bacteria,1MV4J@1224|Proteobacteria,2TT2I@28211|Alphaproteobacteria,4BCGZ@82115|Rhizobiaceae 28211|Alphaproteobacteria P C-terminal region of aryl-sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C k59_912536_2 1229909.NSED_05840 4.46e-53 183.0 COG0145@1|root,arCOG01511@2157|Archaea,41SZ7@651137|Thaumarchaeota 651137|Thaumarchaeota E N-methylhydantoinase A acetone carboxylase, beta subunit - - - - - - - - - - - - Hydant_A_N,Hydantoinase_A k59_1262845_1 879309.HMPREF9199_0555 2.23e-15 82.4 COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,4H32C@909932|Negativicutes 909932|Negativicutes V thiol reductant ABC exporter, CydD subunit cydD - - ko:K16013,ko:K16014 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k59_662235_1 1442599.JAAN01000010_gene251 6.08e-53 182.0 COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria,1RQX0@1236|Gammaproteobacteria,1XA7P@135614|Xanthomonadales 135614|Xanthomonadales V FtsX-like permease family - - - - - - - - - - - - - k59_1514155_1 882378.RBRH_00043 9.39e-100 314.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2VHQ3@28216|Betaproteobacteria,1K0K1@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k59_872557_1 1458275.AZ34_16555 0.000189 46.2 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2VITF@28216|Betaproteobacteria,4ABU5@80864|Comamonadaceae 28216|Betaproteobacteria EQ PFAM Hydantoinase B oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B k59_1063168_1 1149133.ppKF707_3868 6.95e-112 326.0 COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,1YDQS@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043918,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_0125,iPC815.YPO3411,iSDY_1059.SDY_0028 Spermine_synt_N,Spermine_synth k59_122493_1 671143.DAMO_2615 1.65e-27 110.0 COG0312@1|root,COG0312@2|Bacteria 2|Bacteria S metallopeptidase activity - - - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD k59_122493_2 671143.DAMO_0140 3.65e-19 79.0 COG1278@1|root,COG1278@2|Bacteria,2NPXP@2323|unclassified Bacteria 2|Bacteria K 'Cold-shock' DNA-binding domain cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k59_122534_1 436308.Nmar_1716 1.67e-16 74.7 COG0494@1|root,arCOG01073@2157|Archaea,41T73@651137|Thaumarchaeota 651137|Thaumarchaeota L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX k59_122534_2 1229909.NSED_09130 6.92e-150 429.0 COG1522@1|root,arCOG01586@2157|Archaea,41T3N@651137|Thaumarchaeota 651137|Thaumarchaeota K AsnC-type helix-turn-helix domain - - - - - - - - - - - - HTH_24 k59_172503_1 1175306.GWL_42120 4.16e-86 262.0 COG0583@1|root,COG0583@2|Bacteria,1NUAB@1224|Proteobacteria,2VNR5@28216|Betaproteobacteria,476H8@75682|Oxalobacteraceae 28216|Betaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k59_14323_1 1304883.KI912532_gene751 5.01e-40 142.0 2C5U9@1|root,318BZ@2|Bacteria,1RK4D@1224|Proteobacteria,2VKK4@28216|Betaproteobacteria,2KVF8@206389|Rhodocyclales 206389|Rhodocyclales S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp k59_412699_1 1234364.AMSF01000013_gene647 1.46e-72 239.0 COG4772@1|root,COG4772@2|Bacteria,1NTC4@1224|Proteobacteria,1RPFQ@1236|Gammaproteobacteria,1X3G7@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_912928_1 436308.Nmar_0088 1.48e-122 377.0 COG1201@1|root,arCOG00557@2157|Archaea,41S8P@651137|Thaumarchaeota 651137|Thaumarchaeota L DEAD/H associated - - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C k59_912936_1 1385517.N800_06385 5.47e-24 100.0 COG3913@1|root,COG3913@2|Bacteria,1P1K2@1224|Proteobacteria,1S7YG@1236|Gammaproteobacteria,1X9TC@135614|Xanthomonadales 135614|Xanthomonadales S type VI secretion protein - - - ko:K11890 ko02025,map02025 - - - ko00000,ko00001,ko02044 - - - DUF2094 k59_912936_2 1538295.JY96_05300 3.5e-24 100.0 COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,2VIJS@28216|Betaproteobacteria,1KN8E@119065|unclassified Burkholderiales 28216|Betaproteobacteria M OmpA family - - - ko:K02557,ko:K03286 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1,1.B.6 - - BON,OmpA k59_1417944_2 1357272.AVEO02000145_gene1365 6.63e-80 246.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,1Z4VY@136849|Pseudomonas syringae group 1236|Gammaproteobacteria F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974 DHO_dh k59_1518652_1 34506.g3249 9.24e-23 99.0 COG0275@1|root,KOG2782@2759|Eukaryota,38UFJ@33154|Opisthokonta,3BEK8@33208|Metazoa,3CUSP@33213|Bilateria 33208|Metazoa M rRNA (cytosine-N4-)-methyltransferase activity - - - - - - - - - - - - Methyltransf_5 k59_1518652_2 887062.HGR_02887 2.98e-15 75.9 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,4ABEI@80864|Comamonadaceae 28216|Betaproteobacteria D Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE k59_1067126_2 1234364.AMSF01000015_gene3243 1.2e-79 240.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1SA4Q@1236|Gammaproteobacteria,1X3T9@135614|Xanthomonadales 135614|Xanthomonadales L DNA mismatch repair protein MutT - - - - - - - - - - - - DUF1289,NUDIX k59_618996_1 626887.J057_16155 9.17e-46 151.0 2E4J2@1|root,32ZE4@2|Bacteria,1N7YM@1224|Proteobacteria,1S4GF@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3775) - - - - - - - - - - - - DUF3775 k59_279900_2 1118235.CAJH01000034_gene2179 6.03e-09 53.5 COG3847@1|root,COG3847@2|Bacteria 2|Bacteria U Flp Fap pilin component - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - Flp_Fap k59_619089_1 1163407.UU7_10401 9.77e-39 132.0 COG2142@1|root,COG2142@2|Bacteria,1MZND@1224|Proteobacteria,1SAC6@1236|Gammaproteobacteria,1X7KQ@135614|Xanthomonadales 135614|Xanthomonadales C succinate dehydrogenase sdhD - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k59_619089_2 767434.Fraau_1643 1.68e-67 206.0 COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,1SBDX@1236|Gammaproteobacteria,1X6J3@135614|Xanthomonadales 135614|Xanthomonadales C succinate dehydrogenase - - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt k59_130055_1 580332.Slit_0536 6.24e-73 241.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,44VNC@713636|Nitrosomonadales 28216|Betaproteobacteria NU General secretory system II protein E domain protein - - - ko:K02454,ko:K02652,ko:K12276 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - GAF,T2SSE,T2SSE_N k59_1067241_1 1122236.KB905141_gene735 6.18e-118 347.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2VIHH@28216|Betaproteobacteria,2KKPS@206350|Nitrosomonadales 28216|Betaproteobacteria S PFAM cobalamin synthesis protein - - - - - - - - - - - - CobW_C,cobW k59_230089_1 330214.NIDE0896 1.38e-134 396.0 COG1271@1|root,COG1271@2|Bacteria 2|Bacteria C aerobic electron transport chain - - 1.10.3.14 ko:K00425,ko:K08738 ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00153,M00595 R10151,R11325 RC00061,RC03151,RC03152 ko00000,ko00001,ko00002,ko01000 3.D.4.3,3.D.4.6 - - Cyt_bd_oxida_I,Cytochrome_CBB3 k59_667125_2 35754.JNYJ01000071_gene4280 2.23e-55 187.0 COG2124@1|root,COG2124@2|Bacteria,2HECW@201174|Actinobacteria,4DBVH@85008|Micromonosporales 201174|Actinobacteria Q Cytochrome P450 - - - - - - - - - - - - p450 k59_567041_1 287.DR97_4302 3.6e-115 344.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1YDYW@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3323,iPC815.YPO3377 CTP_synth_N,GATase k59_230160_1 1048339.KB913029_gene811 8.09e-17 79.3 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4ERFQ@85013|Frankiales 201174|Actinobacteria EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0047727,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.4.99.13,5.4.99.2 ko:K01848,ko:K11942 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase k59_767186_1 666685.R2APBS1_0703 1.43e-100 315.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1X499@135614|Xanthomonadales 135614|Xanthomonadales O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k59_67962_1 436308.Nmar_0193 9.83e-82 256.0 COG0527@1|root,arCOG00861@2157|Archaea,41SFK@651137|Thaumarchaeota 651137|Thaumarchaeota E Amino acid kinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase k59_818305_1 1173264.KI913949_gene500 1.4e-59 203.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1G175@1117|Cyanobacteria,1H7RY@1150|Oscillatoriales 1117|Cyanobacteria H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iJN678.ribA DHBP_synthase,GTP_cyclohydro2 k59_19162_1 686578.AFFX01000008_gene2752 1.29e-111 352.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria 1236|Gammaproteobacteria M mechanosensitive ion channel kefA GO:0005575,GO:0005623,GO:0005886,GO:0006884,GO:0008150,GO:0008361,GO:0009987,GO:0009992,GO:0016020,GO:0016043,GO:0019725,GO:0030104,GO:0032535,GO:0042592,GO:0044464,GO:0048878,GO:0055082,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - ko:K05802,ko:K22051 - - - - ko00000,ko02000 1.A.23.1.1,1.A.23.1.2,1.A.23.1.3 - - MS_channel,MscS_TM,MscS_porin k59_180258_1 477228.YO5_06521 5.37e-58 190.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria,1Z1AX@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria K COG2207 AraC-type DNA-binding domain-containing proteins oruR - - - - - - - - - - - Arabinose_bd,HTH_18 k59_180258_2 1082705.JIBP01000008_gene479 1.35e-06 48.9 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RPQC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S alcohol dehydrogenase adhP - 1.1.1.1 ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k59_1268531_1 1500890.JQNL01000001_gene925 1.56e-37 140.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1X41T@135614|Xanthomonadales 135614|Xanthomonadales T Histidine kinase styS - - - - - - - - - - - HATPase_c,PAS_8 k59_1268531_2 1163409.UUA_08236 4.08e-10 59.7 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X3II@135614|Xanthomonadales 135614|Xanthomonadales T CheY-like receiver AAA-type ATPase and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k59_767359_1 1122603.ATVI01000005_gene3073 4.69e-24 94.7 COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,1S23R@1236|Gammaproteobacteria,1X9EB@135614|Xanthomonadales 135614|Xanthomonadales C Ribulose bisphosphate carboxylase, small chain - - - - - - - - - - - - RuBisCO_small k59_767359_2 231434.JQJH01000024_gene2085 8.27e-28 109.0 COG0464@1|root,COG0464@2|Bacteria,1MUCN@1224|Proteobacteria,2TVFY@28211|Alphaproteobacteria,3N9VM@45404|Beijerinckiaceae 28211|Alphaproteobacteria O ATPase family associated with various cellular activities (AAA) cbbX - - - - - - - - - - - AAA k59_767427_1 1169143.KB911034_gene981 3.29e-55 186.0 COG2203@1|root,COG2203@2|Bacteria,1MXCJ@1224|Proteobacteria,2WF47@28216|Betaproteobacteria,1K6EQ@119060|Burkholderiaceae 28216|Betaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,HTH_17 k59_365416_2 317013.NY99_14875 2.08e-66 211.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1X3B7@135614|Xanthomonadales 135614|Xanthomonadales J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C k59_667487_1 1245471.PCA10_50240 2.64e-58 192.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,1RNFN@1236|Gammaproteobacteria,1YD1A@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C methylmalonate-semialdehyde dehydrogenase mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k59_230812_1 1500893.JQNB01000001_gene2538 5.61e-97 299.0 COG3693@1|root,COG3693@2|Bacteria,1QU1M@1224|Proteobacteria,1T1M6@1236|Gammaproteobacteria,1XD4J@135614|Xanthomonadales 135614|Xanthomonadales G Beta-galactosidase - - - - - - - - - - - - Glyco_hydro_35 k59_1268854_1 745411.B3C1_02865 3.85e-119 353.0 COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1J5AT@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate astD GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.71 ko:K06447 ko00330,ko01100,map00330,map01100 - R05049 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k59_1268854_2 745411.B3C1_02860 7.26e-10 58.5 COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria,1J6DB@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Arginine N-succinyltransferase beta subunit astA - 2.3.1.109 ko:K00673 ko00330,ko01100,map00330,map01100 - R00832 RC00004,RC00064 ko00000,ko00001,ko01000 - - - AstA k59_1469656_1 287.DR97_4125 4.55e-34 126.0 COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,1RNTW@1236|Gammaproteobacteria,1YEQD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008776,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016741,GO:0016742,GO:0016772,GO:0016774,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iSDY_1059.SDY_1135 ATP-grasp,Epimerase k59_1469656_2 95619.PM1_0216530 4.91e-26 97.1 COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,1SGHW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Fe-S protein - - - ko:K06938 - - - - ko00000 - - - DUF1289 k59_1469656_3 521719.ATXQ01000004_gene1747 1.16e-66 207.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1S3WC@1236|Gammaproteobacteria,1YDGI@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Bacterial transferase hexapeptide (six repeats) yrdA - - - - - - - - - - - Hexapep,Hexapep_2 k59_1167907_1 1005395.CSV86_27729 6.61e-101 313.0 COG0128@1|root,COG0287@1|root,COG0128@2|Bacteria,COG0287@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1YWHE@136845|Pseudomonas putida group 1236|Gammaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 1.3.1.12,1.3.1.43,2.5.1.19 ko:K00210,ko:K00220,ko:K00800 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00022,M00025,M00040 R00732,R01728,R03460 RC00125,RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase,PDH k59_567593_1 69328.PVLB_22995 4.15e-40 136.0 COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG k59_567593_2 1245471.PCA10_05790 2.62e-57 181.0 COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1YGB1@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE k59_619886_1 1541883.A0A088FRR6_9CAUD 8.87e-66 219.0 4QB5I@10239|Viruses,4QPQ9@28883|Caudovirales,4QI9F@10662|Myoviridae 10662|Myoviridae S Type III restriction enzyme, res subunit - - - - - - - - - - - - - k59_469895_1 322710.Avin_14640 1.77e-218 607.0 COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway nqrF GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0048037,GO:0050136,GO:0050660,GO:0050662,GO:0051179,GO:0051234,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071949,GO:0097159,GO:0098796,GO:1901265,GO:1901363,GO:1902494 1.6.5.8 ko:K00351 - - - - ko00000,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k59_281165_1 1182590.BN5_01397 8.84e-75 232.0 COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1YFGG@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K LysR substrate binding domain cysB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - ko:K13634 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k59_19657_1 380358.XALC_2217 1.99e-121 363.0 COG3669@1|root,COG3669@2|Bacteria,1N8B5@1224|Proteobacteria,1RWUY@1236|Gammaproteobacteria,1X79B@135614|Xanthomonadales 135614|Xanthomonadales G alpha-l-fucosidase fucA1 - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,Fucosidase_C k59_767791_1 322710.Avin_39950 1.22e-53 183.0 COG0477@1|root,COG0477@2|Bacteria,1QTWJ@1224|Proteobacteria,1T1QY@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily mdtD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K18326 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.1.3.26 - - MFS_1,MFS_3,TRI12 k59_231116_1 745411.B3C1_02025 1.03e-36 145.0 COG1404@1|root,COG1404@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,1J663@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Belongs to the peptidase S8 family - - - - - - - - - - - - Inhibitor_I9,PA,Peptidase_S8 k59_1418619_1 1041147.AUFB01000099_gene3 1.95e-77 244.0 COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,2U26E@28211|Alphaproteobacteria,4BCIN@82115|Rhizobiaceae 28211|Alphaproteobacteria L DDE_Tnp_1-associated - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_assoc k59_1017904_1 382245.ASA_4363 1.12e-110 337.0 COG4773@1|root,COG4773@2|Bacteria,1QTT0@1224|Proteobacteria,1RNBT@1236|Gammaproteobacteria,1Y5Y3@135624|Aeromonadales 135624|Aeromonadales P TonB dependent receptor - - - ko:K02014,ko:K16088 - - - - ko00000,ko02000 1.B.14,1.B.14.1.10,1.B.14.1.3,1.B.14.1.8 - - Plug,TonB_dep_Rec k59_667856_1 1459636.NTE_02739 1.88e-10 60.5 COG1741@1|root,arCOG02935@2157|Archaea 2157|Archaea S Belongs to the Pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C k59_717693_1 1452718.JBOY01000035_gene2067 7.34e-29 119.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1R9DM@1224|Proteobacteria,1S0EG@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Histidine kinase retS - - ko:K20972 ko02025,map02025 - - - ko00000,ko00001,ko01001,ko02022 - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Response_reg k59_68647_1 1500890.JQNL01000001_gene1960 3.63e-46 157.0 COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,1RNVY@1236|Gammaproteobacteria,1X4ZF@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB k59_1119387_1 310539.Q5G7M7_9CAUD 8.07e-23 102.0 4QB5I@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPQ9@28883|Caudovirales,4QKRP@10699|Siphoviridae 10699|Siphoviridae S helicase activity - - - - - - - - - - - - - k59_620112_1 1245471.PCA10_00170 8.27e-101 304.0 COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,1RNVQ@1236|Gammaproteobacteria,1YDXI@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P TrkA-N domain trkA GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655 - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - iE2348C_1286.E2348C_3552 TrkA_C,TrkA_N k59_1168155_1 1123020.AUIE01000034_gene5336 1.25e-127 383.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1YD3X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k59_567902_1 3880.AES69832 1.8e-75 242.0 28Q3A@1|root,2QWRZ@2759|Eukaryota,37IKA@33090|Viridiplantae,3GANT@35493|Streptophyta,4JV38@91835|fabids 35493|Streptophyta J Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns matK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - ko:K20000 - - - - ko00000,ko03016 - - - Intron_maturas2,MatK_N k59_918187_1 384676.PSEEN4218 1.26e-121 350.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k59_1318524_1 1123227.KB899338_gene1087 2.85e-33 132.0 COG0468@1|root,COG0468@2|Bacteria,1PK58@1224|Proteobacteria,2UB77@28211|Alphaproteobacteria,2JV8V@204441|Rhodospirillales 204441|Rhodospirillales L AAA domain - - - - - - - - - - - - AAA_24 k59_1318524_3 1541883.A0A088FVF0_9CAUD 2.21e-13 71.6 4QBP3@10239|Viruses,4QPEQ@28883|Caudovirales,4QJCZ@10662|Myoviridae 10662|Myoviridae S PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - - k59_668027_1 47716.JOFH01000015_gene5737 9.8e-99 293.0 COG3618@1|root,COG3618@2|Bacteria,2IB8W@201174|Actinobacteria 201174|Actinobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 k59_668027_2 1096930.L284_14745 4.61e-09 57.8 COG0583@1|root,COG0583@2|Bacteria,1Q531@1224|Proteobacteria,2U0V4@28211|Alphaproteobacteria,2K0BE@204457|Sphingomonadales 204457|Sphingomonadales K LysR family - - - - - - - - - - - - HTH_1,LysR_substrate k59_1382436_1 1125863.JAFN01000001_gene1426 2.19e-41 148.0 COG0701@1|root,COG0701@2|Bacteria,1QNSW@1224|Proteobacteria,42YSX@68525|delta/epsilon subdivisions,2WUI1@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Predicted permease - - - - - - - - - - - - ArsP_1 k59_768087_1 745411.B3C1_01415 7.67e-63 215.0 COG1025@1|root,COG1025@2|Bacteria,1QTVC@1224|Proteobacteria,1T1IG@1236|Gammaproteobacteria,1J4KX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the peptidase M16 family - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C,Peptidase_M16_M k59_1582477_1 1163408.UU9_15762 7.63e-14 70.1 COG0235@1|root,COG0235@2|Bacteria,1RE8T@1224|Proteobacteria,1S3UF@1236|Gammaproteobacteria,1X4MF@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) mtnB - 4.2.1.109 ko:K08964 ko00270,ko01100,map00270,map01100 M00034 R07392 RC01939 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II k59_1582477_2 1234364.AMSF01000016_gene1661 1.01e-52 167.0 2E69Z@1|root,330XW@2|Bacteria,1NC2S@1224|Proteobacteria,1SDZ1@1236|Gammaproteobacteria,1X7Z3@135614|Xanthomonadales 135614|Xanthomonadales P Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - - - - - - - - - - HIPIP,TAT_signal k59_568056_1 1211777.BN77_3009 7.4e-47 156.0 COG0346@1|root,COG0346@2|Bacteria,1RGIX@1224|Proteobacteria,2U85R@28211|Alphaproteobacteria,4BF7R@82115|Rhizobiaceae 28211|Alphaproteobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase,Glyoxalase_2 k59_568056_2 272568.GDI3513 1.11e-100 295.0 COG1651@1|root,COG1651@2|Bacteria,1R5HB@1224|Proteobacteria,2UQT5@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Thioredoxin - - - - - - - - - - - - Thioredoxin_4 k59_668193_1 436308.Nmar_1388 1.83e-125 371.0 COG1032@1|root,arCOG01357@2157|Archaea,41SCX@651137|Thaumarchaeota 651137|Thaumarchaeota C Radical SAM - - - - - - - - - - - - Radical_SAM k59_68981_1 640512.BC1003_2050 3.86e-70 222.0 COG4977@1|root,COG4977@2|Bacteria,1QTV9@1224|Proteobacteria,2VZTS@28216|Betaproteobacteria,1KFEG@119060|Burkholderiaceae 28216|Betaproteobacteria K AraC-type transcriptional regulator N-terminus - - - - - - - - - - - - AraC_N,HTH_18 k59_718000_1 321327.CYA_2851 3.83e-65 210.0 COG0668@1|root,COG0668@2|Bacteria,1G08V@1117|Cyanobacteria,1GZQV@1129|Synechococcus 1117|Cyanobacteria M Mechanosensitive ion channel mscS - - - - - - - - - - - MS_channel k59_1483183_2 1218075.BAYA01000005_gene1901 1.11e-05 50.8 COG1506@1|root,COG1506@2|Bacteria,1R968@1224|Proteobacteria,2VPQM@28216|Betaproteobacteria,1K3RN@119060|Burkholderiaceae 28216|Betaproteobacteria E Tannase and feruloyl esterase - - - - - - - - - - - - Tannase k59_378860_1 1499686.BN1079_01941 2.02e-82 255.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the DegT DnrJ EryC1 family per - - - - - - - - - - - DegT_DnrJ_EryC1 k59_784724_2 381666.PHG168 3.24e-82 261.0 COG1196@1|root,COG3593@1|root,COG1196@2|Bacteria,COG3593@2|Bacteria,1MXAH@1224|Proteobacteria,2VMFD@28216|Betaproteobacteria,1K0GD@119060|Burkholderiaceae 28216|Betaproteobacteria DL AAA ATPase domain - - - - - - - - - - - - AAA_15,AAA_21 k59_1136757_1 1395571.TMS3_0118815 2.31e-65 215.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - - - - - - - - - - - AMP-binding,Haem_oxygenas_2 k59_1286140_2 1089551.KE386572_gene4511 1.24e-54 182.0 COG4857@1|root,COG4857@2|Bacteria,1MXBW@1224|Proteobacteria,2TR0Z@28211|Alphaproteobacteria,4BRV5@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Phosphotransferase enzyme family - - - - - - - - - - - - APH k59_1336020_1 390235.PputW619_1823 9.76e-43 157.0 COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,1RP2N@1236|Gammaproteobacteria,1YWUR@136845|Pseudomonas putida group 1236|Gammaproteobacteria G PFAM glycoside hydrolase, family 13 domain protein treZ - 2.4.1.18,3.2.1.141 ko:K00700,ko:K01236 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110,R09995,R11256 RC00049 ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,CBM_48,DUF3459 k59_1286228_1 497321.C664_03977 1.94e-64 204.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHZW@28216|Betaproteobacteria,2KVY6@206389|Rhodocyclales 206389|Rhodocyclales O prohibitin homologues - - - - - - - - - - - - Band_7 k59_1336093_1 1165096.ARWF01000001_gene1297 1.04e-12 71.2 COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,2KMAQ@206350|Nitrosomonadales 206350|Nitrosomonadales M Belongs to the peptidase S11 family - - - ko:K07262 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S11 k59_1336093_2 1430440.MGMSRv2_0223 0.000146 45.1 COG0730@1|root,COG0730@2|Bacteria,1R7DA@1224|Proteobacteria 1224|Proteobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE k59_1240455_1 1499686.BN1079_03079 5.08e-54 170.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria 1236|Gammaproteobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p k59_1240455_2 287.DR97_1871 5.81e-50 159.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1YGQA@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 k59_1483515_1 436308.Nmar_0021 1.28e-91 282.0 COG3263@1|root,arCOG01962@2157|Archaea,41SV3@651137|Thaumarchaeota 651137|Thaumarchaeota P Sodium hydrogen exchanger - - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - Na_H_Exchanger k59_379101_2 1234364.AMSF01000080_gene3041 2.9e-55 193.0 COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,1SE9G@1236|Gammaproteobacteria,1X3VM@135614|Xanthomonadales 135614|Xanthomonadales S ankyrin repeat ank2 - - ko:K06867 - - - - ko00000 - - - Ank,Ank_2,Ank_4,Ank_5 k59_434784_1 745411.B3C1_12449 4.87e-48 159.0 COG4701@1|root,COG4701@2|Bacteria,1RC6A@1224|Proteobacteria,1S2FQ@1236|Gammaproteobacteria,1J78K@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF721) Y3619 - - - - - - - - - - - DUF721 k59_434791_1 314345.SPV1_00932 3.7e-14 75.1 COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria 1224|Proteobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N k59_685616_1 1156919.QWC_23590 1.48e-42 159.0 COG3501@1|root,COG4253@1|root,COG3501@2|Bacteria,COG4253@2|Bacteria,1MU7Q@1224|Proteobacteria,2VJDF@28216|Betaproteobacteria,3T2DD@506|Alcaligenaceae 28216|Betaproteobacteria U protein conserved in bacteria - - - ko:K11904 ko03070,map03070 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - DUF2345,Phage_GPD,T6SS_Vgr k59_785007_1 880073.Calab_2811 1.54e-60 207.0 COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2NPC4@2323|unclassified Bacteria 2|Bacteria P Voltage gated chloride channel - - - ko:K03281 - - - - ko00000 2.A.49 - iAF987.Gmet_3470 CBS,TrkA_C,Voltage_CLC k59_1536937_1 237727.NAP1_08045 8.38e-09 57.8 COG1028@1|root,COG1028@2|Bacteria,1MX8B@1224|Proteobacteria,2U26N@28211|Alphaproteobacteria,2K4EG@204457|Sphingomonadales 204457|Sphingomonadales IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k59_1483736_1 1429851.X548_16100 7.04e-92 279.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RP71@1236|Gammaproteobacteria,1X5JW@135614|Xanthomonadales 135614|Xanthomonadales C COG1062 Zn-dependent alcohol dehydrogenases, class III - - 1.1.1.90 ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N k59_86291_1 1254432.SCE1572_04165 3.69e-58 211.0 COG0515@1|root,COG0642@1|root,COG0745@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WKF3@28221|Deltaproteobacteria 28221|Deltaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - AAA_16,GAF_2,HATPase_c,HisKA,PAS_4,Pkinase,Response_reg k59_1336411_1 666685.R2APBS1_2420 3.9e-12 64.3 COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria,1S4NN@1236|Gammaproteobacteria,1XCB8@135614|Xanthomonadales 135614|Xanthomonadales IQ short chain dehydrogenase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k59_1336411_2 666685.R2APBS1_2419 8.08e-69 215.0 COG0500@1|root,COG0500@2|Bacteria,1QWHM@1224|Proteobacteria,1T47V@1236|Gammaproteobacteria,1XCTD@135614|Xanthomonadales 135614|Xanthomonadales Q Methyltransferase - - - - - - - - - - - - Methyltransf_11 k59_434924_1 1123487.KB892840_gene75 3.82e-152 437.0 COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2VJSA@28216|Betaproteobacteria,2KVEF@206389|Rhodocyclales 206389|Rhodocyclales C Pyruvate:ferredoxin oxidoreductase core domain II padG - 1.2.1.58 ko:K18355 ko00360,map00360 - R02450 RC00004,RC02860 br01601,ko00000,ko00001,ko01000 - - - PFOR_II,POR_N k59_585082_1 666685.R2APBS1_3541 8.67e-17 78.6 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,1X3FK@135614|Xanthomonadales 135614|Xanthomonadales F Belongs to the bacterial glucokinase family glk GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase k59_1035855_2 765420.OSCT_0015 1.07e-18 86.7 COG0110@1|root,COG0110@2|Bacteria 2|Bacteria S O-acyltransferase activity - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac k59_1435104_1 301.JNHE01000026_gene3058 2.35e-27 108.0 2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,1YJ00@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_1435104_2 322710.Avin_46040 5.24e-09 55.8 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iSSON_1240.SSON_4131 Semialdhyde_dh,Semialdhyde_dhC k59_1137212_2 436308.Nmar_0602 2.98e-17 75.1 arCOG08744@1|root,arCOG08744@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_1483960_1 1131266.ARWQ01000011_gene103 1.62e-45 148.0 arCOG07440@1|root,arCOG07440@2157|Archaea,41STP@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_935341_1 1000565.METUNv1_02456 4.63e-82 265.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KURM@206389|Rhodocyclales 206389|Rhodocyclales NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB - - - - - - - - - - - - GAF,T2SSE,T2SSE_N k59_685844_2 426355.Mrad2831_1298 2.23e-17 84.0 COG1835@1|root,COG1835@2|Bacteria,1R4WZ@1224|Proteobacteria,2VF7I@28211|Alphaproteobacteria,1JU5B@119045|Methylobacteriaceae 28211|Alphaproteobacteria I PFAM acyltransferase 3 - - - - - - - - - - - - Acyl_transf_3 k59_1435164_1 1234364.AMSF01000015_gene3234 2.12e-165 468.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,1X3H0@135614|Xanthomonadales 135614|Xanthomonadales S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obgE - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 k59_735139_1 1163409.UUA_16553 4.76e-55 178.0 290UJ@1|root,2ZNGJ@2|Bacteria,1RBSP@1224|Proteobacteria,1S3RZ@1236|Gammaproteobacteria,1X749@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_735139_2 1320556.AVBP01000013_gene1708 2.76e-21 93.2 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,2TTA3@28211|Alphaproteobacteria,43IU7@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K Peptidase_C39 like family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3335 k59_1036099_1 379731.PST_3272 6.87e-87 256.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1Z09H@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - iJN746.PP_0560 DHquinase_II k59_1036099_2 1177154.Y5S_02184 7.39e-14 67.4 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1XJMR@135619|Oceanospirillales 135619|Oceanospirillales I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl k59_1086986_1 1500890.JQNL01000001_gene662 1.1e-13 72.0 COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SH3N@1236|Gammaproteobacteria,1X4NY@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - - - - - - - - - - SPOR k59_1086986_2 666685.R2APBS1_1416 5.81e-64 209.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,1RMB0@1236|Gammaproteobacteria,1X32Z@135614|Xanthomonadales 135614|Xanthomonadales H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M k59_86751_1 642227.HA49_20860 1.16e-42 144.0 2D8SX@1|root,32TRV@2|Bacteria,1N3T6@1224|Proteobacteria,1SPW6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane bound FAD containing D-sorbitol dehydrogenase - - - - - - - - - - - - FAD-SLDH k59_86751_2 642227.HA49_20855 1.01e-59 198.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,4BU1P@82986|Tatumella 1236|Gammaproteobacteria E GMC oxidoreductase - - - - - - - - - - - - DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8 k59_982975_1 384765.SIAM614_19726 3.06e-59 191.0 COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase - - - ko:K07494 - - - - ko00000 - - - DDE_3 k59_982975_2 1144312.PMI09_02139 5.32e-16 72.8 COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,4BC2J@82115|Rhizobiaceae 28211|Alphaproteobacteria L Transposase and inactivated - - - ko:K07494 - - - - ko00000 - - - DDE_3 k59_735413_1 1122137.AQXF01000004_gene1452 3.34e-36 142.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,2U2QG@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k59_536270_1 1333856.L686_22305 3.38e-108 329.0 COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Fe-S oxidoreductase dgcB - - ko:K21834 - - - - ko00000 - - - CCG,DUF3483,Fer4_8 k59_785608_1 497321.C664_09883 1.55e-89 278.0 COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria,2VJEQ@28216|Betaproteobacteria,2KUQ3@206389|Rhodocyclales 206389|Rhodocyclales G BT1 family - - - - - - - - - - - - BT1 k59_86927_1 1245471.PCA10_52920 2.33e-112 327.0 COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,1S0HM@1236|Gammaproteobacteria,1YCY1@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - - - - - - - - - - Methyltrans_RNA k59_86927_2 1523503.JPMY01000037_gene1872 9.32e-26 100.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria 1236|Gammaproteobacteria E (ABC) transporter artM_2 - 3.6.3.21 ko:K02028,ko:K02029 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran k59_640439_1 1123508.JH636453_gene5805 7.02e-25 107.0 COG3391@1|root,COG3391@2|Bacteria,2IY8U@203682|Planctomycetes 203682|Planctomycetes M Integrin alpha (beta-propellor repeats). - - - - - - - - - - - - VCBS k59_1484935_1 2340.JV46_13500 1.77e-77 250.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1J5CM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k59_1137833_1 1479235.KK366039_gene1862 2.81e-46 160.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RR4K@1236|Gammaproteobacteria,1XRDV@135619|Oceanospirillales 135619|Oceanospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k59_1036521_1 3880.AES88230 1.53e-128 405.0 COG0085@1|root,KOG0214@2759|Eukaryota,37HVP@33090|Viridiplantae,3G72V@35493|Streptophyta 33090|Viridiplantae K rna polymerase rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 k59_1241510_1 1234364.AMSF01000082_gene2996 1.47e-110 345.0 COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales 135614|Xanthomonadales Q Lamin Tail Domain - - - - - - - - - - - - Calx-beta,LTD k59_735749_1 322710.Avin_52170 3.31e-96 286.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSSON_1240.SSON_3886,iYL1228.KPN_04138 ATP-synt k59_735749_2 1218352.B597_004855 3.96e-28 111.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1Z15X@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSbBS512_1146.SbBS512_E4187 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k59_490737_1 322710.Avin_11880 3.07e-67 214.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Oxidative deamination of D-amino acids thiO GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 ko:K03153 ko00730,ko01100,map00730,map01100 - R07463 RC01788 ko00000,ko00001,ko01000 - - - DAO k59_340253_1 402777.KB235904_gene3166 5.98e-18 88.2 COG2905@1|root,COG5000@1|root,COG5001@1|root,COG2905@2|Bacteria,COG5000@2|Bacteria,COG5001@2|Bacteria,1G0BS@1117|Cyanobacteria,1H9V4@1150|Oscillatoriales 1117|Cyanobacteria T Diguanylate cyclase - - - - - - - - - - - - CBS,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k59_983383_1 330214.NIDE4281 1.26e-68 216.0 COG0491@1|root,COG1396@1|root,COG0491@2|Bacteria,COG1396@2|Bacteria,3J17T@40117|Nitrospirae 40117|Nitrospirae K Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B k59_1485624_1 94624.Bpet2209 1.66e-61 207.0 COG3451@1|root,COG3451@2|Bacteria,1MXH0@1224|Proteobacteria,2VKE0@28216|Betaproteobacteria,3T1UJ@506|Alcaligenaceae 28216|Betaproteobacteria U Type IV secretory pathway VirB4 components trbE - - ko:K20530 ko02024,map02024 - - - ko00000,ko00001,ko02044 3.A.7.4 - - CagE_TrbE_VirB k59_1485624_2 999541.bgla_1g24970 2.13e-56 175.0 COG5268@1|root,COG5268@2|Bacteria,1MZ8D@1224|Proteobacteria,2VSEB@28216|Betaproteobacteria,1K9A6@119060|Burkholderiaceae 28216|Betaproteobacteria NU Type IV secretory pathway, VirB3-like protein trbD - - ko:K20529 ko02024,map02024 - - - ko00000,ko00001,ko02044 3.A.7.4 - - VirB3 k59_1485624_3 999541.bgla_1g24980 4.26e-52 166.0 COG3838@1|root,COG3838@2|Bacteria,1RH2I@1224|Proteobacteria,2VS6W@28216|Betaproteobacteria,1K80Z@119060|Burkholderiaceae 28216|Betaproteobacteria U PFAM Conjugal transfer protein TrbC - - - ko:K20528 ko02024,map02024 - - - ko00000,ko00001,ko02044 3.A.7.4 - - TrbC k59_435914_1 436308.Nmar_1297 3.53e-106 315.0 COG1798@1|root,COG1849@1|root,arCOG01224@2157|Archaea,arCOG04161@2157|Archaea,41SC2@651137|Thaumarchaeota 651137|Thaumarchaeota H diphthine synthase - - 2.1.1.98 ko:K20215 - - R04481,R08468,R08469,R10306 RC00003,RC00190,RC01155,RC02136,RC02308 ko00000,ko01000 - - - DUF357,TP_methylase k59_1485692_1 1245471.PCA10_40390 4.03e-95 290.0 COG0833@1|root,COG0833@2|Bacteria,1QTSM@1224|Proteobacteria,1RNI2@1236|Gammaproteobacteria,1YF3U@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Amino acid permease rocE - - ko:K02205,ko:K11733 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.2 - - AA_permease k59_1241842_1 742821.HMPREF9464_01752 4.88e-12 62.0 COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,4PRCD@995019|Sutterellaceae 28216|Betaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 k59_1241842_2 666685.R2APBS1_3507 1.5e-79 241.0 COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,1SDNN@1236|Gammaproteobacteria,1X44C@135614|Xanthomonadales 135614|Xanthomonadales S Las17-binding protein actin regulator - - - - - - - - - - - - Ysc84 k59_586215_1 1234364.AMSF01000016_gene1739 6.46e-136 405.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,1RNRX@1236|Gammaproteobacteria,1X3E8@135614|Xanthomonadales 135614|Xanthomonadales P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N k59_1088315_1 322710.Avin_34690 9.01e-69 212.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria J chain release factor yaeJ GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 k59_1287647_1 436308.Nmar_0299 7.01e-33 125.0 COG0036@1|root,COG3959@1|root,arCOG01053@2157|Archaea,arCOG05046@2157|Archaea,41SBE@651137|Thaumarchaeota 651137|Thaumarchaeota G Transketolase, thiamine diphosphate binding domain - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim,Transketolase_N k59_1088352_1 1245471.PCA10_32870 6.6e-118 338.0 COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,1RRRU@1236|Gammaproteobacteria,1YDR9@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E phosphoserine phosphatase homoserine phosphotransferase bifunctional protein thrH - 2.7.1.39,3.1.3.3 ko:K02203 ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230 M00018 R00582,R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HAD,Hydrolase k59_87590_1 745411.B3C1_10592 2.57e-113 342.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1J5FD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T GTP-binding protein TypA typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k59_1337775_1 1229909.NSED_05665 3.01e-25 97.4 arCOG05491@1|root,arCOG05491@2157|Archaea,41SVB@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_1337775_2 1229909.NSED_05660 1.1e-59 194.0 COG0012@1|root,arCOG00357@2157|Archaea,41S8X@651137|Thaumarchaeota 651137|Thaumarchaeota J GTPase of unknown function C-terminal - - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,MMR_HSR1_C,TGS k59_786404_1 1500890.JQNL01000001_gene2946 7.08e-77 257.0 COG3250@1|root,COG3250@2|Bacteria,1R32T@1224|Proteobacteria,1SF8P@1236|Gammaproteobacteria,1X8W4@135614|Xanthomonadales 135614|Xanthomonadales G Beta-1,3-glucanase - - - - - - - - - - - - F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_64 k59_38325_1 1444770.AF72_04780 4.69e-37 135.0 COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,1S2UH@1236|Gammaproteobacteria,1X5ED@135614|Xanthomonadales 135614|Xanthomonadales P phosphate-selective porin oprO - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P k59_1186119_1 1163407.UU7_05007 3.64e-91 276.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,1X60Z@135614|Xanthomonadales 135614|Xanthomonadales K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k59_1486257_1 1131553.JIBI01000001_gene1450 9.3e-44 153.0 COG2220@1|root,COG2220@2|Bacteria,1MUY6@1224|Proteobacteria,2VM81@28216|Betaproteobacteria 28216|Betaproteobacteria S hydrolase activity - - - - - - - - - - - - Lactamase_B_3 k59_1287932_1 290397.Adeh_0413 5.31e-45 164.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2YWE3@29|Myxococcales 28221|Deltaproteobacteria CP NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k59_1037196_1 1500890.JQNL01000001_gene3390 2.16e-81 253.0 COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,1T23I@1236|Gammaproteobacteria,1X4Q8@135614|Xanthomonadales 135614|Xanthomonadales EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 k59_1486652_1 382464.ABSI01000012_gene2034 1.03e-92 296.0 COG1501@1|root,COG1501@2|Bacteria,46TKY@74201|Verrucomicrobia,2IU43@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolases family 31 - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Gal_mutarotas_2,Glyco_hydro_31 k59_586948_1 1500893.JQNB01000001_gene469 3.67e-76 253.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,1X3CF@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor for ferrienterochelin and colicins - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k59_1288424_1 666685.R2APBS1_0843 2.89e-78 236.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,1RMQ2@1236|Gammaproteobacteria,1X4S4@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx k59_1288424_2 983545.Glaag_2104 1.94e-07 54.3 COG4240@1|root,COG4240@2|Bacteria,1QUTA@1224|Proteobacteria,1T23W@1236|Gammaproteobacteria,466GQ@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG4240 Predicted kinase - - 2.7.1.31 ko:K15918 ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ArgK,PRK k59_537807_1 1217658.F987_04115 9.12e-23 92.8 2ABJH@1|root,3110V@2|Bacteria,1RJQT@1224|Proteobacteria,1S63S@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF4339) - - - - - - - - - - - - DUF4339 k59_920569_2 1211777.BN77_p11225 4.87e-18 77.4 COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,2U947@28211|Alphaproteobacteria,4BFJC@82115|Rhizobiaceae 28211|Alphaproteobacteria E Urease, gamma subunit ureA - 3.5.1.5 ko:K01430,ko:K14048 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_beta,Urease_gamma k59_322706_1 95619.PM1_0200445 6.25e-105 307.0 COG1586@1|root,COG1586@2|Bacteria,1MXPT@1224|Proteobacteria,1RQSX@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speD GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO3412,iSDY_1059.SDY_0027 AdoMet_dc k59_1020392_1 1234364.AMSF01000017_gene1476 3.31e-55 187.0 COG2199@1|root,COG3447@1|root,COG3447@2|Bacteria,COG3706@2|Bacteria,1R7GZ@1224|Proteobacteria,1RZEZ@1236|Gammaproteobacteria,1XA6S@135614|Xanthomonadales 135614|Xanthomonadales T MASE1 - - - - - - - - - - - - GGDEF,MASE1 k59_770343_1 1500897.JQNA01000002_gene193 1.71e-76 254.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1K5XI@119060|Burkholderiaceae 28216|Betaproteobacteria V AcrB/AcrD/AcrF family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k59_884653_1 1100720.ALKN01000026_gene1697 2.96e-86 271.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VGZE@28216|Betaproteobacteria,4AGKN@80864|Comamonadaceae 28216|Betaproteobacteria IQ AMP-binding enzyme C-terminal domain - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C k59_1522238_1 330214.NIDE3200 7.01e-83 254.0 COG1234@1|root,COG1234@2|Bacteria,3J113@40117|Nitrospirae 40117|Nitrospirae S tRNA 3'-trailer cleavage - - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - - k59_1121873_1 1118153.MOY_07527 1.97e-42 148.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1XJCE@135619|Oceanospirillales 135619|Oceanospirillales D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 k59_1223767_1 1395571.TMS3_0104550 5.87e-79 244.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the peptidase M20A family. ArgE subfamily argE GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0008777,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_4488 M20_dimer,Peptidase_M20,Peptidase_M28 k59_1223791_1 1234364.AMSF01000033_gene335 3.88e-98 302.0 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,1RN6T@1236|Gammaproteobacteria,1X4M2@135614|Xanthomonadales 135614|Xanthomonadales N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C k59_71275_1 1163408.UU9_16196 2.23e-58 193.0 COG1266@1|root,COG1266@2|Bacteria,1NID0@1224|Proteobacteria,1SUC2@1236|Gammaproteobacteria,1X6ZA@135614|Xanthomonadales 135614|Xanthomonadales S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi k59_1223927_1 1095769.CAHF01000022_gene41 1.05e-08 56.6 COG1024@1|root,COG1024@2|Bacteria,1MUD7@1224|Proteobacteria,2VQ37@28216|Betaproteobacteria 28216|Betaproteobacteria I Pfam Enoyl-CoA hydratase isomerase - - - ko:K13816 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - ECH_1 k59_1223927_2 1095769.CAHF01000022_gene40 5.49e-37 132.0 COG5424@1|root,COG5424@2|Bacteria,1QVK0@1224|Proteobacteria 1224|Proteobacteria H Iron-containing redox enzyme - - - - - - - - - - - - Haem_oxygenas_2 k59_473253_1 1234364.AMSF01000055_gene1105 2.09e-29 116.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1S0CW@1236|Gammaproteobacteria,1X673@135614|Xanthomonadales 135614|Xanthomonadales NT COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain - - - ko:K06597 ko02020,map02020 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheB_methylest k59_473253_2 1234364.AMSF01000055_gene1104 3.64e-81 243.0 COG0835@1|root,COG0835@2|Bacteria,1NA8G@1224|Proteobacteria,1SCB2@1236|Gammaproteobacteria,1X6S4@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis signal transduction protein - - - ko:K06598 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035 - - - CheW k59_135313_1 767434.Fraau_0677 4.06e-11 60.1 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,1X6FU@135614|Xanthomonadales 135614|Xanthomonadales J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A k59_135313_2 1234364.AMSF01000027_gene3513 1.05e-119 353.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,1X39Y@135614|Xanthomonadales 135614|Xanthomonadales U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY k59_1271868_1 225117.XP_009350076.1 7.37e-92 295.0 COG0050@1|root,COG0480@1|root,KOG0460@2759|Eukaryota,KOG0465@2759|Eukaryota,37K55@33090|Viridiplantae,3G82M@35493|Streptophyta,4JJGU@91835|fabids 35493|Streptophyta J Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - - - - - - - - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k59_1585996_1 497321.C664_08178 2.63e-108 326.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,2KVH2@206389|Rhodocyclales 206389|Rhodocyclales G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,iPGM_N k59_670805_1 1439940.BAY1663_03632 8.1e-79 243.0 COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria 1236|Gammaproteobacteria C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway dmpP GO:0003674,GO:0003824,GO:0004497,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0018662,GO:0018958,GO:0018959,GO:0019336,GO:0019439,GO:0044237,GO:0044248,GO:0046191,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 - ko:K16246 ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220 M00548 R03560,R03608,R10042,R10043 RC00046,RC00490 ko00000,ko00001,ko00002 - - - FAD_binding_6,Fer2,NAD_binding_1 k59_670805_2 1439940.BAY1663_03631 2.26e-18 78.2 2DGRK@1|root,32U7S@2|Bacteria,1N22H@1224|Proteobacteria,1S6UD@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phenol hydroxylase conserved region dmpO - - ko:K16245 ko00361,ko00362,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00623,map01100,map01120,map01220 M00548 R03560,R03608,R10042,R10043 RC00046,RC00490 ko00000,ko00001,ko00002 - - - Phenol_monoox k59_1271935_1 396588.Tgr7_0454 3.51e-90 280.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,1WWS0@135613|Chromatiales 135613|Chromatiales P inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 k59_821792_1 1234364.AMSF01000055_gene1076 9.86e-106 328.0 COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RPAW@1236|Gammaproteobacteria,1X45I@135614|Xanthomonadales 135614|Xanthomonadales E peptidase - - - - - - - - - - - - Peptidase_S9 k59_921038_1 1163408.UU9_09437 2.14e-24 97.8 COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SASG@1236|Gammaproteobacteria,1X798@135614|Xanthomonadales 135614|Xanthomonadales CO COG0526 Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA,Redoxin k59_921038_2 1234364.AMSF01000053_gene1319 1.1e-30 111.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,1X6EW@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II k59_1175423_1 1122614.JHZF01000020_gene194 1.72e-104 311.0 COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TUQT@28211|Alphaproteobacteria,2PESG@252301|Oceanicola 28211|Alphaproteobacteria L MULE transposase domain - - - - - - - - - - - - Transposase_mut k59_1392321_1 1109445.AGSX01000189_gene3791 1.11e-106 326.0 COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,1RMIU@1236|Gammaproteobacteria,1Z0PZ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S UxpB protein uxpB - - ko:K07093 - - - - ko00000 - - - DUF839 k59_478861_1 748247.AZKH_1721 7.87e-75 249.0 COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,2KUB6@206389|Rhodocyclales 206389|Rhodocyclales ET His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA k59_1425390_1 1500890.JQNL01000001_gene2476 2.41e-75 245.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1X3IX@135614|Xanthomonadales 135614|Xanthomonadales C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase k59_192151_1 1268237.G114_00090 2.62e-69 227.0 COG2194@1|root,COG2194@2|Bacteria,1MWJY@1224|Proteobacteria,1RN4T@1236|Gammaproteobacteria,1Y5BP@135624|Aeromonadales 135624|Aeromonadales S Cellulose biosynthesis protein BcsG - - - - - - - - - - - - CBP_BcsG k59_892268_1 1131266.ARWQ01000009_gene955 7.87e-63 204.0 COG0079@1|root,arCOG04273@2157|Archaea,41SGU@651137|Thaumarchaeota 651137|Thaumarchaeota E PFAM Aminotransferase class I and II - - 4.1.1.81 ko:K04720 ko00860,map00860 - R06530 RC00517 ko00000,ko00001,ko01000 - - - Aminotran_1_2 k59_1127227_1 767434.Fraau_0434 7.76e-67 213.0 COG4307@1|root,COG4307@2|Bacteria,1MW31@1224|Proteobacteria,1RRA7@1236|Gammaproteobacteria,1X4AW@135614|Xanthomonadales 135614|Xanthomonadales S Putative zinc-binding metallo-peptidase - - - - - - - - - - - - Peptidase_Mx,zinc-ribbon_6 k59_1127227_2 1163407.UU7_09992 2.12e-55 187.0 COG0644@1|root,COG0644@2|Bacteria,1R41S@1224|Proteobacteria,1SME7@1236|Gammaproteobacteria,1X4AF@135614|Xanthomonadales 135614|Xanthomonadales C Tryptophan halogenase - - - - - - - - - - - - Trp_halogenase k59_1075842_1 1005395.CSV86_17512 2.73e-83 254.0 COG0583@1|root,COG0583@2|Bacteria,1N3XX@1224|Proteobacteria,1RXKV@1236|Gammaproteobacteria,1YX3Z@136845|Pseudomonas putida group 1236|Gammaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k59_1229867_1 1395571.TMS3_0104915 8.81e-95 289.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,1RMR6@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG4664 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - - - - - - - - - - DctM k59_1425494_1 1234364.AMSF01000025_gene3675 9.08e-86 275.0 arCOG05967@1|root,2Z8PR@2|Bacteria,1QSXZ@1224|Proteobacteria,1RWJW@1236|Gammaproteobacteria,1X3YX@135614|Xanthomonadales 135614|Xanthomonadales S Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A - - - - - - - - - - - - PNGaseA k59_526010_1 194439.CT0906 1.95e-113 354.0 COG0553@1|root,COG0553@2|Bacteria,1FEYH@1090|Chlorobi 1090|Chlorobi L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N k59_1075929_1 1234364.AMSF01000037_gene91 1.25e-114 343.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1X5AR@135614|Xanthomonadales 135614|Xanthomonadales K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k59_1075929_2 1163407.UU7_02977 8e-60 204.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1X4G8@135614|Xanthomonadales 135614|Xanthomonadales J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc k59_1175716_1 745411.B3C1_18261 1.02e-114 336.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1J52U@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria D COG1077 Actin-like ATPase involved in cell morphogenesis mreB GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k59_892550_1 1163407.UU7_03052 2.33e-124 365.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1X3A1@135614|Xanthomonadales 135614|Xanthomonadales C E3 component of 2-oxoglutarate dehydrogenase complex ldp - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim k59_292770_1 658612.MD26_03410 1.69e-100 316.0 COG1215@1|root,COG5309@1|root,COG1215@2|Bacteria,COG5309@2|Bacteria,1MWF8@1224|Proteobacteria,1RPVG@1236|Gammaproteobacteria 1236|Gammaproteobacteria M transferase - - - - - - - - - - - - Glyco_tranf_2_3 k59_575965_1 1120949.KB903294_gene3782 1.35e-06 51.2 COG1028@1|root,COG1028@2|Bacteria,2GIVT@201174|Actinobacteria 201174|Actinobacteria IQ Short-chain dehydrogenase reductase sdr - - - - - - - - - - - - adh_short_C2 k59_575965_2 1229909.NSED_03265 1.75e-53 176.0 COG2084@1|root,arCOG00247@2157|Archaea,41SI2@651137|Thaumarchaeota 651137|Thaumarchaeota I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k59_328941_1 1234364.AMSF01000015_gene3328 4.36e-41 141.0 COG0705@1|root,COG0705@2|Bacteria,1RB4A@1224|Proteobacteria,1S2UY@1236|Gammaproteobacteria,1X43K@135614|Xanthomonadales 135614|Xanthomonadales S membrane protein (homolog of Drosophila rhomboid) - - - - - - - - - - - - Rhomboid k59_328941_2 1234364.AMSF01000015_gene3329 2.37e-10 60.1 COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,1RPWM@1236|Gammaproteobacteria,1X3G3@135614|Xanthomonadales 135614|Xanthomonadales S phenazine biosynthesis protein PhzF family - - - - - - - - - - - - PhzC-PhzF k59_725778_1 1163407.UU7_02997 6.87e-86 273.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,1X3VD@135614|Xanthomonadales 135614|Xanthomonadales J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 k59_1592893_3 1123261.AXDW01000007_gene2269 4.43e-55 180.0 COG2866@1|root,COG2866@2|Bacteria,1MYRD@1224|Proteobacteria,1T1MH@1236|Gammaproteobacteria,1X3C7@135614|Xanthomonadales 135614|Xanthomonadales E Succinylglutamate desuccinylase / Aspartoacylase family - - - - - - - - - - - - AstE_AspA,DUF2817 k59_1592955_1 745411.B3C1_08918 3.58e-83 254.0 COG0583@1|root,COG0583@2|Bacteria,1MU2E@1224|Proteobacteria,1RQ66@1236|Gammaproteobacteria,1J5WD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k59_1230207_1 266264.Rmet_0542 5.72e-17 81.3 COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,2VMCZ@28216|Betaproteobacteria,1K6MT@119060|Burkholderiaceae 28216|Betaproteobacteria F P-aminobenzoate N-oxygenase AurF - - - - - - - - - - - - AurF k59_1230207_2 867900.Celly_2913 1.46e-06 50.8 COG3665@1|root,COG3665@2|Bacteria,4NGIF@976|Bacteroidetes,1HYFG@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF1989) - - - ko:K09967 - - - - ko00000 - - - DUF1989 k59_576171_1 1234364.AMSF01000005_gene769 5.98e-57 182.0 2B0R0@1|root,31T35@2|Bacteria,1QQSU@1224|Proteobacteria,1RTGE@1236|Gammaproteobacteria,1X7FZ@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_293214_1 395019.Bmul_5401 1.95e-114 336.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2VHSQ@28216|Betaproteobacteria,1JZPY@119060|Burkholderiaceae 28216|Betaproteobacteria C Cytochrome d ubiquinol oxidase, subunit II appB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II k59_479555_1 243365.CV_2262 4.65e-34 132.0 COG0477@1|root,COG2814@2|Bacteria,1NDUV@1224|Proteobacteria 1224|Proteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k59_1593218_1 1123253.AUBD01000009_gene2333 2.59e-54 176.0 COG1586@1|root,COG1586@2|Bacteria,1MXPT@1224|Proteobacteria,1RQSX@1236|Gammaproteobacteria,1X32W@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speD - 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - - AdoMet_dc k59_1593218_2 666685.R2APBS1_3392 6.24e-53 171.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,1X3QC@135614|Xanthomonadales 135614|Xanthomonadales K Transcriptional regulator clp GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0017076,GO:0019001,GO:0019219,GO:0019222,GO:0030551,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032561,GO:0035438,GO:0036094,GO:0043167,GO:0043168,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - Crp,HTH_Crp_2,cNMP_binding k59_526502_1 1207063.P24_17347 2.52e-74 233.0 COG2755@1|root,COG2755@2|Bacteria,1QM85@1224|Proteobacteria,2U34V@28211|Alphaproteobacteria 28211|Alphaproteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - - k59_827402_1 330214.NIDE0766 2.61e-70 223.0 COG0849@1|root,COG0849@2|Bacteria,3J0Q3@40117|Nitrospirae 40117|Nitrospirae D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA k59_1528004_1 1452718.JBOY01000023_gene271 3.48e-118 341.0 COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,1RPX9@1236|Gammaproteobacteria 1236|Gammaproteobacteria L endonuclease I endA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005576,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019439,GO:0034641,GO:0034655,GO:0042597,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 3.1.21.1 ko:K01150 - - - - ko00000,ko01000 - - - Endonuclease_1 k59_973783_1 666685.R2APBS1_1305 2.51e-78 253.0 COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,1RNZM@1236|Gammaproteobacteria,1X4Z4@135614|Xanthomonadales 135614|Xanthomonadales M protein involved in outer membrane biogenesis asmA - - ko:K07290 - - - - ko00000 9.B.121 - - AsmA k59_893216_1 745411.B3C1_03315 2.63e-68 225.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1J5PW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H TonB-dependent Receptor Plug Domain - - - ko:K02014,ko:K16092 - - - - ko00000,ko02000 1.B.14,1.B.14.3 - - Plug,TonB_dep_Rec k59_629698_1 380358.XALC_2274 7.33e-173 491.0 COG3547@1|root,COG3547@2|Bacteria,1NCHY@1224|Proteobacteria,1S1BB@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k59_1476626_1 1395516.PMO01_00320 1.43e-28 113.0 COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RN7K@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - Arabinose_bd,HTH_18 k59_1277457_1 1234364.AMSF01000082_gene3002 2.21e-62 192.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1X6IC@135614|Xanthomonadales 135614|Xanthomonadales K MerR family transcriptional regulator VL23_01195 - - - - - - - - - - - MerR_1 k59_426062_1 1267535.KB906767_gene558 1.24e-42 159.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y78P@57723|Acidobacteria 57723|Acidobacteria KLTU Protein tyrosine kinase - - - - - - - - - - - - PD40,Pkinase k59_893262_1 1163730.FFONT_0933 7.84e-28 112.0 COG0674@1|root,arCOG01608@2157|Archaea,2XQ5N@28889|Crenarchaeota 28889|Crenarchaeota C Pyruvate:ferredoxin oxidoreductase core domain II - - 1.2.7.1 ko:K00169 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N k59_479727_1 1149133.ppKF707_2209 2.45e-116 344.0 COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,1RRDH@1236|Gammaproteobacteria,1YEJB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P Ring hydroxylating alpha subunit (catalytic domain) antA - 1.14.12.1,1.14.13.239 ko:K05599,ko:K22443 ko00627,ko01120,map00627,map01120 M00637 R00823,R00825 RC00192 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A k59_526558_1 84531.JMTZ01000014_gene2744 3.21e-34 136.0 2F0WQ@1|root,33TYB@2|Bacteria,1NUIY@1224|Proteobacteria,1SNQQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_1393412_2 1234364.AMSF01000055_gene1038 7.31e-99 297.0 COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,1XC67@135614|Xanthomonadales 135614|Xanthomonadales M transglycosylase - - - - - - - - - - - - DUF4124,SLT k59_28334_1 1234364.AMSF01000016_gene1713 4.05e-69 229.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S6X1@1236|Gammaproteobacteria,1X450@135614|Xanthomonadales 135614|Xanthomonadales S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase k59_193527_1 521719.ATXQ01000001_gene812 2.29e-64 196.0 COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,1YG5C@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Involved in the binding of tRNA to the ribosomes rpsJ GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 k59_426358_1 399739.Pmen_0619 9.45e-77 249.0 COG0784@1|root,COG2199@1|root,COG2200@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1YD18@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - ko:K21025 ko02025,map02025 - - - ko00000,ko00001 - - - EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg k59_426370_1 1500890.JQNL01000001_gene1340 2.53e-123 375.0 COG0243@1|root,COG0243@2|Bacteria,1MU6B@1224|Proteobacteria,1RNXW@1236|Gammaproteobacteria,1X3PR@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdopterin,Molydop_binding k59_827752_1 155515.JP36_01215 4.12e-08 53.9 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,1Y75Q@135625|Pasteurellales 135625|Pasteurellales J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA k59_827752_2 745411.B3C1_02440 3.21e-84 256.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,1J4ZK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus k59_1393849_1 1229909.NSED_08810 3.71e-38 137.0 COG1422@1|root,arCOG02673@2157|Archaea,41SNR@651137|Thaumarchaeota 651137|Thaumarchaeota U membrane - - - - - - - - - - - - DUF106 k59_1128234_1 1395571.TMS3_0118340 2.07e-68 222.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k59_1128240_1 1333856.L686_13435 1.66e-14 68.2 2BR2G@1|root,32K08@2|Bacteria,1QDRG@1224|Proteobacteria,1T9UW@1236|Gammaproteobacteria,1Z3ME@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_1128240_2 626887.J057_13066 1.18e-13 66.6 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,467AM@72275|Alteromonadaceae 1236|Gammaproteobacteria S EVE domain - - - - - - - - - - - - EVE k59_526944_2 1163408.UU9_00949 3.05e-11 62.8 2B298@1|root,31UT1@2|Bacteria,1QSN9@1224|Proteobacteria,1RW59@1236|Gammaproteobacteria,1X835@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_28536_1 555793.WSK_0774 2.11e-86 269.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales 204457|Sphingomonadales C belongs to the aldehyde dehydrogenase family - - 1.2.1.39 ko:K00146 ko00360,ko00643,ko01100,ko01120,map00360,map00643,map01100,map01120 - R02536 RC00080 ko00000,ko00001,ko01000 - - - Aldedh k59_974298_1 1163409.UUA_10296 3.01e-89 272.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1X3NP@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k59_974298_2 1500893.JQNB01000001_gene3337 6.06e-26 103.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria,1X49B@135614|Xanthomonadales 135614|Xanthomonadales C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k59_1231111_1 1532557.JL37_17805 7.2e-125 381.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,3T2IP@506|Alcaligenaceae 28216|Betaproteobacteria C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) aceE GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N k59_144169_1 1163408.UU9_15617 7.59e-55 190.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1X489@135614|Xanthomonadales 135614|Xanthomonadales O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C k59_144169_2 1234364.AMSF01000016_gene1629 2.42e-29 114.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1X4TT@135614|Xanthomonadales 135614|Xanthomonadales O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k59_776945_1 1123354.AUDR01000013_gene516 7.89e-123 366.0 COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2VHSF@28216|Betaproteobacteria,1KS6X@119069|Hydrogenophilales 119069|Hydrogenophilales C Cytochrome D1 heme domain - - 1.7.2.1,1.7.99.1 ko:K15864 ko00910,ko01120,map00910,map01120 M00529 R00143,R00783,R00785 RC00086,RC02797 ko00000,ko00001,ko00002,ko01000 - - - Cytochrom_D1,Cytochrome_CBB3 k59_564933_2 1234364.AMSF01000021_gene1272 7.02e-21 85.9 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1X6DR@135614|Xanthomonadales 135614|Xanthomonadales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H k59_715062_1 644801.Psest_1091 2.14e-94 286.0 COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,1RY3R@1236|Gammaproteobacteria,1Z1WQ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E ABC transporter substrate-binding protein - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k59_715062_2 574966.KB898646_gene3205 4.27e-20 86.3 COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,1RQZM@1236|Gammaproteobacteria,1XI4N@135619|Oceanospirillales 135619|Oceanospirillales E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran k59_1516965_2 1163409.UUA_07458 1.84e-57 188.0 COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,1X33P@135614|Xanthomonadales 135614|Xanthomonadales C Quinone oxidoreductase - - - - - - - - - - - - ADH_N,ADH_zinc_N k59_1116351_2 1245471.PCA10_48680 2.76e-40 148.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1YD67@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k59_277164_1 1001585.MDS_3491 1.32e-92 277.0 COG2084@1|root,COG2084@2|Bacteria,1NS71@1224|Proteobacteria,1S2D0@1236|Gammaproteobacteria,1YDZ0@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k59_1266186_1 420324.KI911992_gene7686 1.97e-50 175.0 COG3637@1|root,COG3637@2|Bacteria,1QUUK@1224|Proteobacteria,2TW8A@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Alginate export - - - - - - - - - - - - Alginate_exp k59_127188_1 1123360.thalar_02885 2.23e-69 227.0 COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,2U068@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome C and Quinol oxidase polypeptide I - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 k59_765165_1 493475.GARC_0604 4.89e-66 216.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,4663D@72275|Alteromonadaceae 1236|Gammaproteobacteria MU RND efflux system, outer membrane lipoprotein oprM - - ko:K18139,ko:K18147 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00649,M00718,M00768,M00822 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2,2.A.6.2.40 - - OEP k59_277316_1 666685.R2APBS1_0167 1.56e-114 356.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1X3B5@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_964973_1 867903.ThesuDRAFT_02209 6.97e-14 72.0 COG2385@1|root,COG2385@2|Bacteria,1TSR0@1239|Firmicutes,249AE@186801|Clostridia 186801|Clostridia D PFAM Stage II sporulation D domain protein - - - ko:K06381 - - - - ko00000 - - - SpoIID k59_964973_2 697284.ERIC2_c28000 1.06e-11 65.5 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,26RP1@186822|Paenibacillaceae 91061|Bacilli J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k59_964985_1 1229909.NSED_09495 1.33e-130 381.0 COG1509@1|root,arCOG03246@2157|Archaea,41SY6@651137|Thaumarchaeota 651137|Thaumarchaeota E TIGRFAM lysine 2,3-aminomutase YodO family protein - - - - - - - - - - - - - k59_1578292_1 640081.Dsui_3074 1.65e-73 232.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2VHCK@28216|Betaproteobacteria,2KUP3@206389|Rhodocyclales 206389|Rhodocyclales K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k59_17323_1 745411.B3C1_06223 4.18e-128 395.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1J5BI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA recB GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5 ko:K03582 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C k59_1467477_1 1234364.AMSF01000016_gene1506 1.07e-169 485.0 COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1X3GD@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon k59_227440_1 1163409.UUA_13110 3.93e-66 213.0 COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,1RN2K@1236|Gammaproteobacteria,1X2Z0@135614|Xanthomonadales 135614|Xanthomonadales K lacI family VL23_05370 - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 k59_515516_1 1163408.UU9_09607 5.45e-43 156.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RYXW@1236|Gammaproteobacteria,1X2ZM@135614|Xanthomonadales 135614|Xanthomonadales C RmuC family rmuC - - ko:K09760 - - - - ko00000 - - - RmuC k59_1517338_1 1231185.BAMP01000005_gene3922 2.54e-21 92.0 COG3568@1|root,COG3568@2|Bacteria,1RB4H@1224|Proteobacteria,2U7TI@28211|Alphaproteobacteria,43QV7@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Endonuclease Exonuclease phosphatase - - - - - - - - - - - - Exo_endo_phos k59_11672_2 1123393.KB891327_gene376 6.14e-64 197.0 COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,1KT17@119069|Hydrogenophilales 119069|Hydrogenophilales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA - 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 k59_1310519_1 767434.Fraau_1207 3.53e-144 424.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1X3C0@135614|Xanthomonadales 135614|Xanthomonadales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_5,UVR,UvrC_HhH_N k59_218684_1 765912.Thimo_1384 4.39e-133 385.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RPQC@1236|Gammaproteobacteria,1X2A7@135613|Chromatiales 135613|Chromatiales S alcohol dehydrogenase - - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N k59_461274_1 767434.Fraau_1626 1.64e-123 361.0 COG5042@1|root,COG5042@2|Bacteria,1NAN9@1224|Proteobacteria,1SKPT@1236|Gammaproteobacteria,1X9HP@135614|Xanthomonadales 135614|Xanthomonadales F Purine nucleoside permease (NUP) - - - - - - - - - - - - NUP k59_118683_1 330214.NIDE1634 9.14e-101 318.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3J101@40117|Nitrospirae 40117|Nitrospirae G Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N k59_611358_1 1390370.O203_02700 1.66e-88 263.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1YG9X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - iE2348C_1286.E2348C_3156,iPC815.YPO0906 GCV_H k59_560324_1 1163408.UU9_01709 1.76e-09 59.7 COG2976@1|root,COG2976@2|Bacteria,1NBUU@1224|Proteobacteria,1STCH@1236|Gammaproteobacteria,1X7QQ@135614|Xanthomonadales 135614|Xanthomonadales S Protein conserved in bacteria - - - - - - - - - - - - - k59_118850_1 1232683.ADIMK_0555 6.08e-31 111.0 COG0251@1|root,COG0251@2|Bacteria,1RH61@1224|Proteobacteria,1S4QT@1236|Gammaproteobacteria,46BX4@72275|Alteromonadaceae 1236|Gammaproteobacteria J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP k59_118850_2 1232683.ADIMK_0556 2.77e-54 181.0 COG0665@1|root,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,1RP7W@1236|Gammaproteobacteria 1236|Gammaproteobacteria E fad dependent oxidoreductase - - - - - - - - - - - - DAO k59_1260720_1 595537.Varpa_3211 2.72e-47 174.0 COG0457@1|root,COG3087@1|root,COG0457@2|Bacteria,COG3087@2|Bacteria,1MVB8@1224|Proteobacteria,2VHKT@28216|Betaproteobacteria,4A9QG@80864|Comamonadaceae 28216|Betaproteobacteria D Cellulose synthase operon protein C C-terminus (BCSC_C) bscS - - ko:K20543 - - - - ko00000,ko02000 1.B.55.3 - - BCSC_C,TPR_16,TPR_19,TPR_4,TPR_7,TPR_8 k59_1110917_1 4572.TRIUR3_00337-P1 2.05e-91 269.0 COG0049@1|root,KOG3291@2759|Eukaryota,37YX8@33090|Viridiplantae,3GNS6@35493|Streptophyta,3KTYP@4447|Liliopsida,3IAPX@38820|Poales 35493|Streptophyta J ribosomal protein S7 - - - - - - - - - - - - Ribosomal_S7 k59_1260739_1 1163408.UU9_03557 6.26e-134 391.0 COG3517@1|root,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,1X3ID@135614|Xanthomonadales 135614|Xanthomonadales S type VI secretion protein - - - ko:K11900 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - VipB k59_660240_1 1000565.METUNv1_00569 1.13e-102 313.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,2KVHT@206389|Rhodocyclales 206389|Rhodocyclales F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase k59_760527_1 757424.Hsero_2561 3.69e-69 221.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VHRJ@28216|Betaproteobacteria,473RQ@75682|Oxalobacteraceae 28216|Betaproteobacteria H AMP-binding enzyme paaK_2 - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 k59_1369946_1 330214.NIDE0629 1.4e-69 215.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis yneN - - - - - - - - - - - AhpC-TSA k59_1111041_1 1151127.KB906339_gene916 4.67e-97 291.0 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RN9X@1236|Gammaproteobacteria,1YRI0@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria C Oxidoreductase FAD-binding domain benC GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.25,1.18.1.7 ko:K05784,ko:K14581,ko:K16161 ko00362,ko00364,ko00622,ko00624,ko00626,ko00627,ko00633,ko00642,ko00680,ko01100,ko01120,ko01200,ko01220,map00362,map00364,map00622,map00624,map00626,map00627,map00633,map00642,map00680,map01100,map01120,map01200,map01220 M00174,M00534,M00551,M00638 R01142,R02968,R05290,R05291,R05422,R05423,R05424,R05425,R05426,R05427,R05428,R05621,R05622,R05665,R06909,R06930,R06937,R07704,R07706,R07709,R07710,R08100,R08101,R08108,R08109,R08110,R09159,R09233 RC00091,RC00098,RC00157,RC00173,RC00270,RC00274,RC00275,RC00490,RC01376,RC01377,RC01378,RC01450,RC01801,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k59_961155_1 1123400.KB904746_gene1347 1.71e-16 73.9 COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,4618D@72273|Thiotrichales 72273|Thiotrichales H Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln k59_961155_2 1163617.SCD_n00097 6.12e-43 149.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria 28216|Betaproteobacteria D Cell shape determining protein, MreB Mrl family mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl k59_810764_1 1380394.JADL01000003_gene4969 7.33e-119 343.0 COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,2JRD7@204441|Rhodospirillales 204441|Rhodospirillales O C-terminal domain of 1-Cys peroxiredoxin - - - - - - - - - - - - 1-cysPrx_C,AhpC-TSA k59_1462252_2 666685.R2APBS1_1005 6.23e-72 228.0 COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,1RRMM@1236|Gammaproteobacteria,1X2YX@135614|Xanthomonadales 135614|Xanthomonadales E phospho-2-dehydro-3-deoxyheptonate aldolase dhs1 - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_2 k59_1111150_1 1234364.AMSF01000015_gene3353 2.66e-99 293.0 COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,1XC92@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1415) - - - ko:K09941 - - - - ko00000 - - - DUF1415 k59_611735_1 767434.Fraau_2409 0.00012 43.1 COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,1RS9U@1236|Gammaproteobacteria,1X6ES@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions rraA - - ko:K02553 - - - - ko00000,ko03019 - - - RraA-like k59_611735_2 1234364.AMSF01000095_gene2583 3.03e-108 320.0 COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,1RNYX@1236|Gammaproteobacteria,1X5AE@135614|Xanthomonadales 135614|Xanthomonadales E Threonine aldolase - - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase k59_169174_1 1304883.KI912532_gene1559 5.29e-05 43.5 2ERQA@1|root,33J9N@2|Bacteria,1NI0Z@1224|Proteobacteria,2VYZY@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_169174_2 859657.RPSI07_3248 2.15e-37 128.0 COG4274@1|root,COG4274@2|Bacteria,1MZVV@1224|Proteobacteria,2VUPM@28216|Betaproteobacteria,1K8BT@119060|Burkholderiaceae 28216|Betaproteobacteria S PFAM GYD family protein - - - - - - - - - - - - GYD k59_510541_1 1500890.JQNL01000001_gene1404 2.53e-35 136.0 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,1X54G@135614|Xanthomonadales 135614|Xanthomonadales T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k59_710797_1 452659.RrIowa_1281 2.99e-08 54.7 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,47EU5@766|Rickettsiales 766|Rickettsiales M Lipoprotein releasing system transmembrane protein lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k59_710797_2 1379698.RBG1_1C00001G0448 1.3e-38 137.0 COG1136@1|root,COG1136@2|Bacteria,2NP7F@2323|unclassified Bacteria 2|Bacteria V Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran k59_311613_1 911239.CF149_00540 3.15e-33 130.0 COG3170@1|root,COG3170@2|Bacteria,1QVRT@1224|Proteobacteria,1T2IA@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Exopolysaccharide biosynthesis protein YbjH - - - - - - - - - - - - Caps_synth_GfcC,YjbH k59_12187_1 393305.YE0304 2.3e-09 54.7 COG2963@1|root,COG2963@2|Bacteria,1N0GS@1224|Proteobacteria,1SZ7N@1236|Gammaproteobacteria,41HF3@629|Yersinia 1236|Gammaproteobacteria L cytoplasmic protein stm0948 SWALL Q8ZQE1 (EMBL AE008740) (133 aa) fasta scores E() - - - - - - - - - - - - - k59_12187_2 273526.SMDB11_1224 1.12e-52 173.0 COG2801@1|root,COG2801@2|Bacteria,1PUMN@1224|Proteobacteria,1RYSS@1236|Gammaproteobacteria 1236|Gammaproteobacteria L PFAM Integrase catalytic region - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 k59_1412481_1 296591.Bpro_2089 1.25e-98 311.0 COG1752@1|root,COG1752@2|Bacteria,1MWH2@1224|Proteobacteria,2W1DW@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF3376) - - - - - - - - - - - - DUF3376,Patatin k59_510680_2 1453496.AT03_10660 2.56e-86 266.0 COG0095@1|root,COG0095@2|Bacteria,1N1T8@1224|Proteobacteria,1RMGI@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes lplA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - iBWG_1329.BWG_4078,iE2348C_1286.E2348C_4684,iECDH10B_1368.ECDH10B_4544,iECDH1ME8569_1439.ECDH1ME8569_4242,iEcDH1_1363.EcDH1_3612,iJO1366.b4386,iSDY_1059.SDY_4647,iY75_1357.Y75_RS22890 BPL_LplA_LipB,Lip_prot_lig_C k59_1261158_1 1229909.NSED_08490 2.94e-73 248.0 COG1404@1|root,arCOG00704@2157|Archaea,41SEM@651137|Thaumarchaeota 651137|Thaumarchaeota O Subtilase family - - - - - - - - - - - - Peptidase_S8 k59_1570443_1 767434.Fraau_1273 6.96e-99 301.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,1RQJW@1236|Gammaproteobacteria,1X4BH@135614|Xanthomonadales 135614|Xanthomonadales P chloride channel clcA - - - - - - - - - - - Voltage_CLC k59_461897_1 1121939.L861_18190 5.22e-29 122.0 COG2304@1|root,COG2931@1|root,COG3210@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,1S3Q4@1236|Gammaproteobacteria,1XK3E@135619|Oceanospirillales 135619|Oceanospirillales Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - VWA_2 k59_60774_1 1234364.AMSF01000055_gene1107 2.15e-89 281.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X5CR@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis protein pilJ - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - MCPsignal,PilJ k59_1111426_1 1229909.NSED_03355 9.71e-62 216.0 COG1196@1|root,arCOG00371@2157|Archaea,41SDS@651137|Thaumarchaeota 651137|Thaumarchaeota D SMC proteins Flexible Hinge Domain - - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge k59_1212469_1 264198.Reut_A0632 2.05e-60 194.0 COG1118@1|root,COG1118@2|Bacteria,1QVTM@1224|Proteobacteria,2WH8A@28216|Betaproteobacteria,1KIIF@119060|Burkholderiaceae 28216|Betaproteobacteria P ABC transporter modC - 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran k59_1212469_2 477184.KYC_26667 1.32e-29 115.0 COG2005@1|root,COG3585@1|root,COG2005@2|Bacteria,COG3585@2|Bacteria,1P9SX@1224|Proteobacteria,2VMCH@28216|Betaproteobacteria,3T3SF@506|Alcaligenaceae 28216|Betaproteobacteria H N-terminal domain of molybdenum-binding protein modE - - ko:K02019 - - - - ko00000,ko03000 - - - HTH_1,TOBE k59_560882_1 767434.Fraau_3224 2.25e-64 199.0 COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,1T193@1236|Gammaproteobacteria,1X6HF@135614|Xanthomonadales 135614|Xanthomonadales I Thioesterase superfamily - - - - - - - - - - - - 4HBT k59_269710_1 1268068.PG5_53900 2.63e-90 283.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RSD3@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Protein of unknown function (DUF1302) - - - - - - - - - - - - DUF1302 k59_560911_1 883126.HMPREF9710_02587 1.35e-77 247.0 COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2VNF0@28216|Betaproteobacteria 28216|Betaproteobacteria M PFAM Carbohydrate-selective porin OprB oprB - - ko:K07267 - - - - ko00000,ko02000 1.B.19.1 - - OprB k59_761011_1 1163407.UU7_14028 1.09e-39 150.0 COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,1RPKB@1236|Gammaproteobacteria,1X9Q7@135614|Xanthomonadales 135614|Xanthomonadales V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD k59_60898_1 745411.B3C1_14857 2.51e-81 263.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1J57S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P cation transport ATPase copA GO:0000041,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035434,GO:0042221,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046688,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0060003,GO:0061687,GO:0070887,GO:0071241,GO:0071248,GO:0071280,GO:0071292,GO:0071944,GO:0090662,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0099131,GO:1902601,GO:1990169 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - iEC55989_1330.EC55989_0497,iECIAI1_1343.ECIAI1_0487,iECO103_1326.ECO103_0460,iECSE_1348.ECSE_0509,iECW_1372.ECW_m0557,iEKO11_1354.EKO11_3363,iWFL_1372.ECW_m0557 E1-E2_ATPase,HMA,Hydrolase k59_1261386_1 1234364.AMSF01000016_gene1557 4.75e-124 375.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1X4F7@135614|Xanthomonadales 135614|Xanthomonadales D Cell division protein ftsk ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - Cupin_4,FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k59_269872_1 371042.NG99_10345 7.37e-69 219.0 COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,1RSNH@1236|Gammaproteobacteria,3X55Z@551|Erwinia 1236|Gammaproteobacteria EG EamA-like transporter family yedA - - - - - - - - - - - EamA k59_811285_1 399739.Pmen_3856 2.48e-43 146.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1YF6C@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Riboflavin synthase ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding k59_1261399_1 1163409.UUA_16258 4.66e-100 300.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1X3S4@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b k59_711136_1 1163408.UU9_07431 4.21e-76 234.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1X3FM@135614|Xanthomonadales 135614|Xanthomonadales F Belongs to the RimK family rimK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k59_711136_2 1234364.AMSF01000058_gene903 2.43e-15 72.4 COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,1X7J9@135614|Xanthomonadales 135614|Xanthomonadales O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease k59_1261427_1 745411.B3C1_17597 7.36e-88 278.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1J59D@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate fadB GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 ko:K01782,ko:K01825 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R04756,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01078,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - iLF82_1304.LF82_0614,iNRG857_1313.NRG857_19200 3HCDH,3HCDH_N,ECH_1 k59_660878_1 1123020.AUIE01000021_gene1036 6.83e-108 322.0 COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,1YDTU@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gabT GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006554,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0017144,GO:0019477,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046440,GO:0047589,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.19,2.6.1.22,2.6.1.48 ko:K07250,ko:K14268 ko00250,ko00280,ko00310,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00310,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R02274,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - iJN746.PP_0214 Aminotran_3 k59_169870_2 436308.Nmar_0018 1.26e-13 66.2 arCOG08804@1|root,arCOG08804@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_761135_2 1479237.JMLY01000001_gene261 2.08e-07 52.4 COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,468JG@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG2863 Cytochrome c553 cycM - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k59_411181_1 1123519.PSJM300_18180 9.37e-18 81.6 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1Z0YG@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - iECSE_1348.ECSE_3895,iJN746.PP_5056 Metalloenzyme,Phosphodiest,iPGM_N k59_411181_2 477228.YO5_17770 6.2e-49 159.0 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,1Z2RU@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria P COG0607 Rhodanese-related sulfurtransferase yibN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k59_711246_1 913325.N799_13465 2.45e-06 52.8 COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,1RQ9W@1236|Gammaproteobacteria,1X5VV@135614|Xanthomonadales 135614|Xanthomonadales L Integrase core domain - - - - - - - - - - - - rve k59_1527041_2 1122603.ATVI01000006_gene557 1.63e-13 72.0 2DFXZ@1|root,2ZTNG@2|Bacteria,1NKM6@1224|Proteobacteria,1STH8@1236|Gammaproteobacteria,1XBRQ@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - LTXXQ k59_478605_1 767434.Fraau_1619 6.48e-56 194.0 COG4774@1|root,COG4774@2|Bacteria,1MVZD@1224|Proteobacteria,1RN2P@1236|Gammaproteobacteria,1X4EM@135614|Xanthomonadales 135614|Xanthomonadales P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_775484_1 1163408.UU9_14475 1.43e-95 295.0 COG0644@1|root,COG0644@2|Bacteria,1MZ3Z@1224|Proteobacteria,1S47W@1236|Gammaproteobacteria,1X4IT@135614|Xanthomonadales 135614|Xanthomonadales C Halogenase - - - - - - - - - - - - Trp_halogenase k59_1326121_1 1206735.BAGG01000229_gene5710 4.02e-10 57.8 COG2018@1|root,COG2018@2|Bacteria,2IHQT@201174|Actinobacteria,4G3ET@85025|Nocardiaceae 201174|Actinobacteria S Roadblock/LC7 domain - - - - - - - - - - - - - k59_1075506_1 999541.bgla_2g06010 4.66e-74 239.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,2W70N@28216|Betaproteobacteria,1KDG0@119060|Burkholderiaceae 28216|Betaproteobacteria G Glycosyl hydrolase family 20, catalytic domain - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - Glyco_hydro_20,Glyco_hydro_20b k59_1075527_1 330214.NIDE0801 5.47e-88 264.0 COG0652@1|root,COG0652@2|Bacteria,3J18H@40117|Nitrospirae 40117|Nitrospirae O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase k59_891938_1 1229909.NSED_09030 6.49e-63 199.0 COG2897@1|root,arCOG02019@2157|Archaea,41SXR@651137|Thaumarchaeota 651137|Thaumarchaeota P Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese k59_1425225_1 1234364.AMSF01000034_gene302 1.75e-23 100.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria,1X3TH@135614|Xanthomonadales 135614|Xanthomonadales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD k59_1425225_2 666685.R2APBS1_3136 6.54e-49 161.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1X31A@135614|Xanthomonadales 135614|Xanthomonadales S abc transporter atp-binding protein lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C k59_628756_1 977880.RALTA_B2059 5.1e-40 147.0 COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1MUAK@1224|Proteobacteria,2WGZT@28216|Betaproteobacteria,1K1AV@119060|Burkholderiaceae 28216|Betaproteobacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07638 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA k59_826561_1 436308.Nmar_1504 1.83e-40 135.0 arCOG08674@1|root,arCOG08674@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_826561_2 436308.Nmar_1503 6.43e-43 144.0 arCOG08675@1|root,arCOG08675@2157|Archaea,41SI5@651137|Thaumarchaeota 651137|Thaumarchaeota C Monooxygenase subunit B protein - - - ko:K10945 ko00680,ko00910,ko01100,ko01120,ko01200,map00680,map00910,map01100,map01120,map01200 M00174,M00528,M00804 R00148,R09518 RC00173,RC02797 ko00000,ko00001,ko00002 - - - Monooxygenase_B k59_1025797_1 437329.A5A3V1_9CAUD 1.25e-45 170.0 4QAY9@10239|Viruses,4QUYA@35237|dsDNA viruses no RNA stage,4QPAN@28883|Caudovirales,4QKV1@10699|Siphoviridae 10699|Siphoviridae S hydrolase activity - - - - - - - - - - - - - k59_328513_1 95619.PM1_0226615 8.71e-85 260.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU twitching motility protein pilU - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE k59_328513_2 626887.J057_06841 1.96e-56 177.0 COG2314@1|root,COG2314@2|Bacteria,1RHUU@1224|Proteobacteria,1S694@1236|Gammaproteobacteria,46AYU@72275|Alteromonadaceae 1236|Gammaproteobacteria S TM2 domain - - - - - - - - - - - - TM2 k59_525738_1 745411.B3C1_10717 1.9e-52 171.0 2DE0K@1|root,2ZK14@2|Bacteria,1P5A8@1224|Proteobacteria,1SVIU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_199293_1 187272.Mlg_1695 3.06e-09 59.7 COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1RSDZ@1236|Gammaproteobacteria,1WVWP@135613|Chromatiales 135613|Chromatiales T PFAM ATP-binding region - - - - - - - - - - - - HATPase_c,HisKA k59_199293_2 375286.mma_3673 1.45e-18 87.4 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,475WV@75682|Oxalobacteraceae 28216|Betaproteobacteria T CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k59_299705_1 153948.NAL212_2064 4.49e-25 109.0 COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2WEJA@28216|Betaproteobacteria,374P7@32003|Nitrosomonadales 28216|Betaproteobacteria EO pdz dhr glgf - - - - - - - - - - - - PDZ_2,Peptidase_M1,Peptidase_M28 k59_780507_2 666685.R2APBS1_2229 6.17e-52 170.0 COG3784@1|root,COG3784@2|Bacteria,1MYIH@1224|Proteobacteria,1S8D2@1236|Gammaproteobacteria,1X61X@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1318) - - - - - - - - - - - - DUF1318 k59_1281785_1 455632.SGR_3585 5.39e-50 169.0 2DZG2@1|root,32V9Q@2|Bacteria 2|Bacteria S Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 k59_978246_1 767434.Fraau_2980 2.68e-12 67.4 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,1X4R9@135614|Xanthomonadales 135614|Xanthomonadales E aminopeptidase - - 3.4.11.14 ko:K01263 - - - - ko00000,ko01000 - - - ERAP1_C,Peptidase_M1 k59_978246_2 1500893.JQNB01000001_gene281 9.73e-51 169.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,1X3SU@135614|Xanthomonadales 135614|Xanthomonadales K Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate k59_1430338_1 927677.ALVU02000001_gene1997 1.96e-05 47.0 COG0500@1|root,COG2226@2|Bacteria,1G0WT@1117|Cyanobacteria 1117|Cyanobacteria Q PFAM O-methyltransferase - - - - - - - - - - - - Dimerisation2,Methyltransf_2 k59_680902_1 237609.PSAKL28_25720 1.19e-55 183.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RPU4@1236|Gammaproteobacteria 1236|Gammaproteobacteria E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - - - - - - - - - - ADH_N,ADH_zinc_N k59_1180593_1 1163407.UU7_11240 2.17e-109 320.0 COG1011@1|root,COG1011@2|Bacteria,1MX48@1224|Proteobacteria,1SNTC@1236|Gammaproteobacteria,1X3KD@135614|Xanthomonadales 135614|Xanthomonadales S haloacid dehalogenase - - - ko:K07025 - - - - ko00000 - - - HAD_2,Hydrolase k59_1031017_1 639030.JHVA01000001_gene2135 2.73e-26 112.0 COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,3Y3YU@57723|Acidobacteria,2JIXB@204432|Acidobacteriia 204432|Acidobacteriia T Two component regulator propeller - - - - - - - - - - - - GGDEF,Reg_prop,Y_Y_Y k59_299865_1 264730.PSPPH_4188 8.73e-58 182.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,1Z7HH@136849|Pseudomonas syringae group 1236|Gammaproteobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K02834 - - - - ko00000,ko03009 - - - RBFA k59_1081087_1 1448139.AI20_08905 1.04e-110 324.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1Y3J4@135624|Aeromonadales 135624|Aeromonadales F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA - 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - - PFK k59_580720_2 1229909.NSED_02840 1.43e-07 55.5 arCOG11721@1|root,arCOG11721@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_249842_1 999541.bgla_1g03820 2.45e-39 137.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,1K0MT@119060|Burkholderiaceae 28216|Betaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k59_249842_2 1266925.JHVX01000004_gene1304 2.07e-31 117.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,371YC@32003|Nitrosomonadales 28216|Betaproteobacteria E TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth k59_1282087_1 745411.B3C1_02085 4.08e-72 227.0 COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria,1J6J6@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U COG3156 Type II secretory pathway, component PulK gspK GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK k59_1479763_1 1231190.NA8A_00795 1.75e-47 173.0 COG0419@1|root,COG1112@1|root,COG0419@2|Bacteria,COG1112@2|Bacteria,1MW2R@1224|Proteobacteria,2TVCV@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG1112 Superfamily I DNA and RNA helicases and helicase subunits - - - - - - - - - - - - AAA_11,AAA_12,PLDc_2 k59_81913_1 1523503.JPMY01000046_gene1331 1.51e-94 285.0 COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S SURF1-like protein surf1 - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 k59_81913_2 644801.Psest_4329 1.51e-52 173.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1Z17X@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria C Heme copper-type cytochrome quinol oxidase, subunit 3 coxC - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k59_249978_1 95619.PM1_0218265 3.74e-22 90.9 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC k59_249978_2 1245471.PCA10_44170 6.01e-83 249.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1YECD@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k59_430591_1 557598.LHK_03012 1.38e-63 213.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,2KPX6@206351|Neisseriales 206351|Neisseriales D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA - - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc k59_978675_1 436308.Nmar_0306 1.55e-55 181.0 COG0500@1|root,arCOG01631@2157|Archaea,41SJC@651137|Thaumarchaeota 651137|Thaumarchaeota Q RNA methylase - - - - - - - - - - - - DOT1 k59_978675_2 436308.Nmar_0307 2.5e-44 145.0 COG1698@1|root,arCOG04308@2157|Archaea,41SRP@651137|Thaumarchaeota 651137|Thaumarchaeota S Belongs to the UPF0147 family - - - ko:K09721 - - - - ko00000 - - - UPF0147 k59_634990_2 1123237.Salmuc_00159 1.07e-31 120.0 COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TRDG@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050,ko:K15554 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - BPD_transp_1 k59_1532731_1 1229909.NSED_05065 1.12e-07 50.4 arCOG07348@1|root,arCOG07348@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_485035_1 1500893.JQNB01000001_gene1945 4.2e-24 99.0 COG3858@1|root,COG3858@2|Bacteria,1N1AG@1224|Proteobacteria,1SRDK@1236|Gammaproteobacteria,1X54K@135614|Xanthomonadales 135614|Xanthomonadales S glycosyl hydrolase - - - - - - - - - - - - Glyco_hydro_18 k59_1332037_1 1453503.AU05_00335 9.92e-73 229.0 COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1YEJZ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Aminotransferase class-III hemL GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUMNK88_1353.UMNK88_158 Aminotran_3 k59_1332037_2 1439940.BAY1663_03498 4.6e-13 68.6 COG0351@1|root,COG0352@1|root,COG0351@2|Bacteria,COG0352@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria 1236|Gammaproteobacteria H phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin k59_832346_1 1229909.NSED_01340 2.3e-75 229.0 COG5424@1|root,arCOG06031@2157|Archaea,41SJK@651137|Thaumarchaeota 651137|Thaumarchaeota H Iron-containing redox enzyme - - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - - k59_375093_1 1160137.KB907308_gene7586 1.05e-48 173.0 COG1018@1|root,COG2258@1|root,COG1018@2|Bacteria,COG2258@2|Bacteria,2I3N3@201174|Actinobacteria,4G9GX@85025|Nocardiaceae 201174|Actinobacteria C 3-alpha domain - - - - - - - - - - - - 3-alpha,FAD_binding_6,Fer2,MOSC,NAD_binding_1 k59_1600216_1 1131266.ARWQ01000035_gene713 1.25e-34 120.0 arCOG08688@1|root,arCOG08688@2157|Archaea,41T55@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_1600216_2 1229909.NSED_06760 2.72e-30 114.0 arCOG08689@1|root,arCOG08689@2157|Archaea,41T5U@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_681587_1 1122201.AUAZ01000021_gene3147 2.46e-21 92.8 COG1783@1|root,COG1783@2|Bacteria 2|Bacteria S DNA packaging - - - ko:K06909 - - - - ko00000 - - - Terminase_3 k59_1600278_1 1151292.QEW_0901 0.000166 49.3 COG0305@1|root,COG0305@2|Bacteria,1VTC0@1239|Firmicutes,24XTJ@186801|Clostridia,25SWT@186804|Peptostreptococcaceae 186801|Clostridia L DnaB-like helicase N terminal domain - - - - - - - - - - - - DnaB,DnaB_C k59_430951_1 935557.ATYB01000009_gene734 2.91e-58 204.0 COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,4BBZJ@82115|Rhizobiaceae 28211|Alphaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_7,PAS_9 k59_531669_1 1245471.PCA10_48710 3.25e-52 172.0 COG0664@1|root,COG0664@2|Bacteria,1RKRH@1224|Proteobacteria,1S42Z@1236|Gammaproteobacteria,1YET6@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding k59_1332268_1 1000565.METUNv1_00162 5.7e-19 78.6 COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2VVV6@28216|Betaproteobacteria,2KX79@206389|Rhodocyclales 206389|Rhodocyclales S Zinc-finger domain - - - - - - - - - - - - zf-CHCC k59_1332268_2 497321.C664_10208 3.59e-82 252.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,2KUZJ@206389|Rhodocyclales 206389|Rhodocyclales E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 k59_1236337_1 666685.R2APBS1_1013 2.53e-137 429.0 COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1X37J@135614|Xanthomonadales 135614|Xanthomonadales S membrane - - - - - - - - - - - - AsmA_2,DUF3971 k59_150057_1 693986.MOC_4658 6.2e-19 82.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,1JSJY@119045|Methylobacteriaceae 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain MA20_22025 - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N,GST_N_3 k59_681815_1 313628.LNTAR_18820 1.01e-71 223.0 COG0302@1|root,COG0302@2|Bacteria 2|Bacteria H gtp cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R03503,R04639,R05046,R05048 RC00002,RC00017,RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3609c GTP_cyclohydroI k59_335137_1 1121943.KB899994_gene910 6.61e-112 328.0 COG1099@1|root,COG1099@2|Bacteria,1MY2H@1224|Proteobacteria,1RTX9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S hydrolase, TatD - - - ko:K07051 - - - - ko00000 - - - TatD_DNase k59_979260_2 436308.Nmar_0533 1.5e-110 322.0 arCOG08681@1|root,arCOG08681@2157|Archaea,41SH9@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_979273_1 1229909.NSED_02265 2.56e-09 56.2 COG1382@1|root,arCOG01342@2157|Archaea,41SPD@651137|Thaumarchaeota 651137|Thaumarchaeota O Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding pfdB - - ko:K04798 - - - - ko00000,ko03110 - - - Prefoldin_2 k59_979273_2 436308.Nmar_0437 1.59e-78 238.0 COG1948@1|root,arCOG04206@2157|Archaea,41SIH@651137|Thaumarchaeota 651137|Thaumarchaeota L ERCC4 domain - - - ko:K10848 ko03420,ko03460,map03420,map03460 - - - ko00000,ko00001,ko01000,ko03032,ko03400 - - - ERCC4,HHH_5 k59_832883_1 745411.B3C1_03290 7.09e-150 428.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1J5CA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_0684,iECSF_1327.ECSF_0680,iEcSMS35_1347.EcSMS35_0777,iLF82_1304.LF82_0146,iNRG857_1313.NRG857_03335,iYL1228.KPN_00758 DAHP_synth_1 k59_1480282_1 379731.PST_1921 2.87e-19 85.5 COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,1RN1I@1236|Gammaproteobacteria,1Z0SV@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 k59_1078620_1 1123366.TH3_05630 3.21e-48 165.0 COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,2TRV8@28211|Alphaproteobacteria,2JRCH@204441|Rhodospirillales 204441|Rhodospirillales E glycine betaine transport - - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k59_1129966_1 436308.Nmar_0409 1.33e-51 175.0 COG0579@1|root,arCOG00754@2157|Archaea,41SXA@651137|Thaumarchaeota 651137|Thaumarchaeota S FAD dependent oxidoreductase - - - ko:K15736 - - - - ko00000,ko01000 - - - DAO k59_373006_1 375286.mma_3314 1.06e-134 393.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2VJWJ@28216|Betaproteobacteria,476U4@75682|Oxalobacteraceae 28216|Betaproteobacteria U Type II/IV secretion system protein cpaF - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE k59_79320_1 521719.ATXQ01000001_gene499 2.29e-107 322.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1YFGX@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k59_1078759_1 666685.R2APBS1_0206 1.82e-60 194.0 COG3806@1|root,COG3806@2|Bacteria,1RI6T@1224|Proteobacteria,1S341@1236|Gammaproteobacteria,1X62R@135614|Xanthomonadales 135614|Xanthomonadales T ChrR Cupin-like domain - - - ko:K07167 - - - - ko00000 - - - Cupin_7 k59_976124_1 767434.Fraau_1566 9.88e-48 171.0 COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,1RNPI@1236|Gammaproteobacteria,1X3G0@135614|Xanthomonadales 135614|Xanthomonadales V abc transporter atp-binding protein cydD - - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran k59_296778_1 1523503.JPMY01000012_gene3182 8.32e-73 245.0 COG0744@1|root,COG0744@2|Bacteria,1NRPB@1224|Proteobacteria,1RNG3@1236|Gammaproteobacteria 1236|Gammaproteobacteria M membrane carboxypeptidase (Penicillin-binding protein) - - - - - - - - - - - - Transgly,Transpeptidase k59_1130202_2 580332.Slit_2084 5.15e-20 87.4 COG4967@1|root,COG4967@2|Bacteria,1N7AC@1224|Proteobacteria,2VW8B@28216|Betaproteobacteria,44W3Z@713636|Nitrosomonadales 28216|Betaproteobacteria NU type IV pilus modification protein PilV - - - ko:K02671 - - - - ko00000,ko02035,ko02044 - - - N_methyl k59_246478_1 1123504.JQKD01000002_gene3544 1.15e-72 226.0 COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHCD@28216|Betaproteobacteria,4ACDR@80864|Comamonadaceae 28216|Betaproteobacteria O Belongs to the GST superfamily gstI - 2.5.1.18 ko:K00799,ko:K11209 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N,GST_N_2 k59_331900_1 1123256.KB907926_gene962 1.17e-97 298.0 COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,1RP19@1236|Gammaproteobacteria,1X39U@135614|Xanthomonadales 135614|Xanthomonadales C acetyl-CoA hydrolase - - 2.8.3.18 ko:K18118 ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200 M00009,M00011 R10343 RC00012,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AcetylCoA_hyd_C,AcetylCoA_hydro k59_30403_1 1234364.AMSF01000053_gene1298 7.4e-28 111.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1X306@135614|Xanthomonadales 135614|Xanthomonadales MU TIGRFAM type I secretion outer membrane protein, TolC family raxC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP k59_30403_2 1163408.UU9_07301 3.01e-35 131.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1X4GI@135614|Xanthomonadales 135614|Xanthomonadales M transferase waaA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_1,Glycos_transf_N k59_196635_1 1211112.ALJC01000087_gene1019 0.000128 45.4 COG2199@1|root,COG2199@2|Bacteria,1R4NY@1224|Proteobacteria,1S193@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Sensory box GGDEF EAL domain-containing protein - - - - - - - - - - - - GGDEF,PAS,PAS_3 k59_632425_1 1234364.AMSF01000056_gene1128 4.29e-72 223.0 COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,1RMKM@1236|Gammaproteobacteria,1X4Q6@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short k59_632425_2 1234364.AMSF01000056_gene1129 1.11e-57 186.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,1RMR3@1236|Gammaproteobacteria,1X2XZ@135614|Xanthomonadales 135614|Xanthomonadales S Serine hydrolase involved in the detoxification of formaldehyde fghA - 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 - Esterase k59_1178666_2 225937.HP15_672 2.85e-44 151.0 2E13U@1|root,32WJ6@2|Bacteria,1NFFY@1224|Proteobacteria,1SIE5@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_1130336_1 1504981.KO116_3199 4.01e-56 196.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,1XNKW@135619|Oceanospirillales 135619|Oceanospirillales S TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM k59_928919_1 1463854.JOHT01000019_gene4844 7.51e-17 77.8 COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria 201174|Actinobacteria L o-methyltransferase - - - - - - - - - - - - Methyltransf_24,Methyltransf_3 k59_928919_2 1122603.ATVI01000010_gene941 3.32e-29 105.0 COG3813@1|root,COG3813@2|Bacteria,1N712@1224|Proteobacteria,1SCGG@1236|Gammaproteobacteria,1X92P@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1272) - - - - - - - - - - - - DUF1272 k59_928930_1 330214.NIDE0429 8.22e-51 170.0 2C1IB@1|root,2ZG3S@2|Bacteria 2|Bacteria S Proto-chlorophyllide reductase 57 kD subunit - - - - - - - - - - - - PCP_red k59_928930_2 330214.NIDE0428 2.35e-18 77.4 COG0776@1|root,COG0776@2|Bacteria,3J19J@40117|Nitrospirae 40117|Nitrospirae L bacterial (prokaryotic) histone like domain - - - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding k59_373272_1 298386.PBPRA2410 1.59e-07 53.5 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XTES@135623|Vibrionales 135623|Vibrionales EH COG0147 Anthranilate para-aminobenzoate synthases component I pabB - 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Anth_synt_I_N,Chorismate_bind k59_373272_2 745411.B3C1_08191 1.74e-46 161.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,1J4X4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Catalyzes the reversible hydration of fumarate to (S)- malate fumA GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0033554,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0047808,GO:0048037,GO:0050163,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1778,iPC815.YPO3335 Fumerase,Fumerase_C k59_297212_1 1247024.JRLH01000009_gene1896 2.44e-07 50.4 COG1476@1|root,COG1476@2|Bacteria,1N58S@1224|Proteobacteria,1S939@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,HTH_31 k59_547787_1 1234364.AMSF01000016_gene1547 1.65e-98 299.0 COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1X3VI@135614|Xanthomonadales 135614|Xanthomonadales L Belongs to the DNA photolyase family phr - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k59_795992_2 1504672.669782891 2.3e-16 79.7 COG2931@1|root,COG2931@2|Bacteria,1R7DP@1224|Proteobacteria 1224|Proteobacteria Q Collagen triple helix repeat - - - - - - - - - - - - Collagen k59_48987_2 365046.Rta_35080 7.38e-53 176.0 COG0697@1|root,COG0697@2|Bacteria,1MX07@1224|Proteobacteria,2VN9W@28216|Betaproteobacteria,4ACVN@80864|Comamonadaceae 28216|Betaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k59_1099854_1 1234364.AMSF01000005_gene716 3.03e-70 221.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1X3E5@135614|Xanthomonadales 135614|Xanthomonadales O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 k59_796190_1 1122201.AUAZ01000002_gene926 1.35e-32 119.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,46CRN@72275|Alteromonadaceae 1236|Gammaproteobacteria M OmpA family pal GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032153,GO:0044425,GO:0044462,GO:0044464,GO:0051301,GO:0071944,GO:0098552 - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA k59_1148582_1 1500890.JQNL01000001_gene1432 5.05e-21 87.8 COG1846@1|root,COG1846@2|Bacteria,1MZY5@1224|Proteobacteria,1SERB@1236|Gammaproteobacteria,1X6S6@135614|Xanthomonadales 135614|Xanthomonadales K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 k59_746712_1 745411.B3C1_00650 6.15e-34 127.0 COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,1RMSI@1236|Gammaproteobacteria,1J56H@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N k59_746712_2 745411.B3C1_00655 1.46e-50 169.0 COG2866@1|root,COG2866@2|Bacteria,1MUMN@1224|Proteobacteria,1RQB4@1236|Gammaproteobacteria,1J8QZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 k59_746733_1 745411.B3C1_12004 1.96e-108 327.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1J4XM@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3323,iPC815.YPO3377 CTP_synth_N,GATase k59_49191_1 335543.Sfum_0418 6.28e-54 175.0 COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2MQHM@213462|Syntrophobacterales 28221|Deltaproteobacteria S Bifunctional nuclease - - - ko:K08999 - - - - ko00000 - - - DNase-RNase k59_1100027_1 1265490.JHVY01000007_gene1658 1.17e-113 336.0 2DBJX@1|root,2Z9P4@2|Bacteria,1MYUJ@1224|Proteobacteria 1224|Proteobacteria S outer membrane (Porin) - - - - - - - - - - - - OprD k59_1499104_1 1163408.UU9_01729 2.98e-104 307.0 COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,1RMVD@1236|Gammaproteobacteria,1X39H@135614|Xanthomonadales 135614|Xanthomonadales G Inositol monophosphatase family - - 3.1.3.15 ko:K05602 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P k59_548405_1 1163408.UU9_16071 2.2e-21 89.0 COG1595@1|root,COG1595@2|Bacteria,1RB1Q@1224|Proteobacteria,1S336@1236|Gammaproteobacteria,1X752@135614|Xanthomonadales 135614|Xanthomonadales K Belongs to the sigma-70 factor family. ECF subfamily rpoE5 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k59_548405_2 666685.R2APBS1_1117 1.65e-54 179.0 COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S5DB@1236|Gammaproteobacteria,1X4XD@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF502) YH67_14670 - - - - - - - - - - - DUF502 k59_848364_1 745411.B3C1_14118 6.36e-97 309.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1J4PF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg k59_848420_1 745411.B3C1_09293 8.66e-107 325.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1J4HD@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O Heat shock 70 kDa protein dnaK GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 k59_1195883_1 266835.14025743 1.01e-81 253.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k59_993385_1 1229909.NSED_08715 3.04e-34 122.0 COG3945@1|root,arCOG01471@2157|Archaea,41T3D@651137|Thaumarchaeota 651137|Thaumarchaeota S Hemerythrin HHE cation binding - - - - - - - - - - - - Hemerythrin k59_993385_2 1229909.NSED_08705 8.73e-55 183.0 COG1012@1|root,arCOG01252@2157|Archaea,41T0F@651137|Thaumarchaeota 651137|Thaumarchaeota C PFAM Aldehyde dehydrogenase - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135,ko:K18601 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh k59_796578_1 857087.Metme_0085 2.75e-52 179.0 COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,1XGZ9@135618|Methylococcales 1236|Gammaproteobacteria L PFAM Transposase, IS4-like - - - - - - - - - - - - DDE_Tnp_1_6,DUF772 k59_49678_1 743720.Psefu_0320 1.61e-18 79.0 COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S4CZ@1236|Gammaproteobacteria,1YYJI@136845|Pseudomonas putida group 1236|Gammaproteobacteria T response regulator, receiver pilG - - ko:K02657,ko:K03413 ko02020,ko02025,ko02030,map02020,map02025,map02030 M00506,M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg k59_49678_2 399739.Pmen_0402 9.61e-36 129.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1YI3S@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Belongs to the prokaryotic GSH synthase family gshB GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_3410,iECP_1309.ECP_2941 GSH-S_ATP,GSH-S_N k59_599066_1 1301098.PKB_2685 2.56e-102 301.0 COG3396@1|root,COG3396@2|Bacteria,1MVYQ@1224|Proteobacteria,1RRSG@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Phenylacetate-CoA oxygenase, PaaI subunit paaC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.14.13.149 ko:K02611 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_1526,iECO111_1330.ECO111_1784,iECSE_1348.ECSE_1475,iECW_1372.ECW_m1524,iEKO11_1354.EKO11_2423,iWFL_1372.ECW_m1524 PaaA_PaaC k59_1299953_1 666685.R2APBS1_1096 7.92e-118 343.0 COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,1RXZI@1236|Gammaproteobacteria,1X4ZB@135614|Xanthomonadales 135614|Xanthomonadales S Esterase lipase - - 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 k59_1299958_1 745411.B3C1_16722 1.77e-101 315.0 COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,1RMQ1@1236|Gammaproteobacteria,1J5G9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L COG0417 DNA polymerase elongation subunit (family B) polB GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02336 - - - - ko00000,ko01000,ko03400 - - - DNA_pol_B,DNA_pol_B_exo1 k59_1348912_1 438753.AZC_3305 2.07e-24 103.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,3EY3D@335928|Xanthobacteraceae 28211|Alphaproteobacteria V AcrB/AcrD/AcrF family MA20_01135 - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran k59_1348912_2 1226994.AMZB01000067_gene1896 4.36e-27 106.0 COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,1RQD2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase k59_1100541_1 1234364.AMSF01000055_gene1037 2.87e-60 197.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X5AM@135614|Xanthomonadales 135614|Xanthomonadales O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k59_1100541_2 398579.Spea_3536 5.21e-38 134.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,2Q9HY@267890|Shewanellaceae 1236|Gammaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N k59_1348956_1 1123392.AQWL01000003_gene290 9.02e-71 233.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,1KSG5@119069|Hydrogenophilales 119069|Hydrogenophilales C Inorganic H+ pyrophosphatase - - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase k59_796832_1 1268068.PG5_65060 2.62e-38 138.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RR0P@1236|Gammaproteobacteria 1236|Gammaproteobacteria E glutamine synthetase glnT - 6.3.1.11,6.3.1.2 ko:K01915,ko:K09470 ko00220,ko00250,ko00330,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00330,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 M00136 R00253,R07414 RC00010,RC00090,RC00096,RC02798 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Gln-synt_C k59_796832_2 1439940.BAY1663_00578 2.41e-72 225.0 COG0034@1|root,COG0034@2|Bacteria,1MWHP@1224|Proteobacteria,1RMGF@1236|Gammaproteobacteria 1236|Gammaproteobacteria F glutamine amidotransferase - - 2.1.1.21 ko:K22081 ko00680,ko01120,map00680,map01120 - R01586 RC00554 ko00000,ko00001,ko01000 - - - GATase_6 k59_98219_1 1163409.UUA_08109 3.42e-58 186.0 COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1X72K@135614|Xanthomonadales 135614|Xanthomonadales S YGGT family - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT k59_698993_1 436308.Nmar_1573 5.6e-88 272.0 COG0519@1|root,arCOG00085@2157|Archaea,41SDI@651137|Thaumarchaeota 651137|Thaumarchaeota F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase k59_698993_2 436308.Nmar_1572 1.16e-20 86.3 arCOG05463@1|root,arCOG05463@2157|Archaea,41SR3@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_393536_1 1229909.NSED_09015 3.07e-98 305.0 COG1269@1|root,arCOG04138@2157|Archaea,41SRH@651137|Thaumarchaeota 651137|Thaumarchaeota C Belongs to the V-ATPase 116 kDa subunit family - - - ko:K02123 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - V_ATPase_I k59_1349196_1 390235.PputW619_2470 2.38e-58 183.0 COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,1S8T4@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Type II secretion system protein G - - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG k59_1349196_2 62928.azo2089 1.2e-15 72.4 COG4968@1|root,COG4968@2|Bacteria,1QVCD@1224|Proteobacteria,2WGQ3@28216|Betaproteobacteria,2KWT8@206389|Rhodocyclales 206389|Rhodocyclales U Prokaryotic N-terminal methylation motif - - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl k59_1549373_1 1240350.AMZE01000027_gene4719 2.71e-55 191.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RNYS@1236|Gammaproteobacteria,1YXK8@136845|Pseudomonas putida group 1236|Gammaproteobacteria E Gluconate 2-dehydrogenase - - 1.1.99.3 ko:K06151 ko00030,ko01100,ko01120,map00030,map01100,map01120 - R01741 RC00084 ko00000,ko00001,ko01000 - - iJN746.PP_3383 GMC_oxred_C,GMC_oxred_N k59_1549373_2 1336237.JAEE01000012_gene853 1.8e-69 225.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,1RMYF@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k59_1500024_2 1234364.AMSF01000056_gene1213 1.14e-86 266.0 COG3522@1|root,COG3522@2|Bacteria,1MXKE@1224|Proteobacteria,1RNCB@1236|Gammaproteobacteria,1X4E5@135614|Xanthomonadales 135614|Xanthomonadales S type VI secretion protein - - - ko:K11893 ko02025,map02025 M00334 - - ko00000,ko00001,ko00002,ko02044 3.A.23.1 - - T6SS_VasE k59_797313_1 392499.Swit_4311 3.91e-87 263.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria,2K5XQ@204457|Sphingomonadales 204457|Sphingomonadales S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - 1.13.11.16 ko:K05713,ko:K15755 ko00360,ko00621,ko01100,ko01120,ko01220,map00360,map00621,map01100,map01120,map01220 M00544,M00545 R04376,R05415,R06788 RC01140,RC01306,RC01364 br01602,ko00000,ko00001,ko00002,ko01000 - - - LigB k59_849180_1 1123053.AUDG01000007_gene3165 1.01e-10 67.4 COG2199@1|root,COG2199@2|Bacteria,1NV1F@1224|Proteobacteria,1RS44@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - 2.7.7.65 ko:K20960 ko05111,map05111 - - - ko00000,ko00001,ko01000 - - - GGDEF,PAS,PAS_3,PAS_4 k59_1349519_1 1149133.ppKF707_1975 1.37e-113 337.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1YDFQ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Glutamate synthase gltD GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iEC042_1314.EC042_3503,iYL1228.KPN_03625 Fer4_11,Fer4_20,Pyr_redox_2 k59_549400_1 1234364.AMSF01000016_gene1732 1.81e-95 298.0 COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,1RPPF@1236|Gammaproteobacteria,1X2YJ@135614|Xanthomonadales 135614|Xanthomonadales P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system kdpB - 3.6.3.12 ko:K01547 ko02020,map02020 - - - ko00000,ko00001,ko01000 3.A.3.7 - - E1-E2_ATPase,Hydrolase k59_947350_1 118005.AWNK01000006_gene1202 3.55e-61 201.0 COG0649@1|root,COG0649@2|Bacteria 2|Bacteria C NAD binding nuoD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa,Complex1_49kDa k59_1048883_1 1500893.JQNB01000001_gene1111 1.18e-54 179.0 COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S49E@1236|Gammaproteobacteria,1X380@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase k59_1048883_2 1552758.NC00_17410 1.19e-11 60.8 COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria,1X6Z5@135614|Xanthomonadales 135614|Xanthomonadales S Domain of unknown function (DUF1820) - - - - - - - - - - - - DUF1820 k59_1549728_1 935863.AWZR01000014_gene2950 1.04e-57 186.0 COG0702@1|root,COG0702@2|Bacteria,1QR3E@1224|Proteobacteria,1S37H@1236|Gammaproteobacteria,1X7W7@135614|Xanthomonadales 135614|Xanthomonadales GM epimerase - - - - - - - - - - - - NAD_binding_10 k59_748267_1 1151127.KB906339_gene916 3.23e-35 128.0 COG0543@1|root,COG0633@1|root,COG0543@2|Bacteria,COG0633@2|Bacteria,1MV72@1224|Proteobacteria,1RN9X@1236|Gammaproteobacteria,1YRI0@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria C Oxidoreductase FAD-binding domain benC GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.25,1.18.1.7 ko:K05784,ko:K14581,ko:K16161 ko00362,ko00364,ko00622,ko00624,ko00626,ko00627,ko00633,ko00642,ko00680,ko01100,ko01120,ko01200,ko01220,map00362,map00364,map00622,map00624,map00626,map00627,map00633,map00642,map00680,map01100,map01120,map01200,map01220 M00174,M00534,M00551,M00638 R01142,R02968,R05290,R05291,R05422,R05423,R05424,R05425,R05426,R05427,R05428,R05621,R05622,R05665,R06909,R06930,R06937,R07704,R07706,R07709,R07710,R08100,R08101,R08108,R08109,R08110,R09159,R09233 RC00091,RC00098,RC00157,RC00173,RC00270,RC00274,RC00275,RC00490,RC01376,RC01377,RC01378,RC01450,RC01801,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 k59_748267_2 1215092.PA6_024_00550 9.73e-45 148.0 COG5517@1|root,COG5517@2|Bacteria,1RAVG@1224|Proteobacteria,1S4XB@1236|Gammaproteobacteria,1YDJX@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria Q Ring hydroxylating beta subunit benB - 1.14.12.10 ko:K05550 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110 RC00270,RC01378,RC01450,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - iYL1228.KPN_01871 Ring_hydroxyl_B k59_1447950_1 446471.Xcel_2243 7.66e-15 72.0 COG1279@1|root,COG1279@2|Bacteria,2IHQ2@201174|Actinobacteria,4F4I2@85017|Promicromonosporaceae 201174|Actinobacteria S LysE type translocator lysE GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - ko:K06895 - - - - ko00000,ko02000 2.A.75.1 - - LysE k59_1447950_2 987059.RBXJA2T_14476 8.23e-15 73.9 COG0583@1|root,COG0583@2|Bacteria,1MWUP@1224|Proteobacteria,2VJPA@28216|Betaproteobacteria,1KKM5@119065|unclassified Burkholderiales 28216|Betaproteobacteria K LysR substrate binding domain iciA - - ko:K05596 - - - - ko00000,ko03000,ko03036 - - - HTH_1,LysR_substrate k59_1549855_1 1430331.EP10_08935 1.83e-05 52.4 COG0338@1|root,COG0338@2|Bacteria,1V1FT@1239|Firmicutes,4HGCH@91061|Bacilli,1WHCW@129337|Geobacillus 91061|Bacilli L Putative phage serine protease XkdF yqbD - - - - - - - - - - - Peptidase_S78_2 k59_1350010_1 1348908.KI518608_gene3458 5.81e-35 129.0 COG3142@1|root,COG3142@2|Bacteria,1UYI8@1239|Firmicutes,4IR0G@91061|Bacilli,1ZHIS@1386|Bacillus 91061|Bacilli P Participates in the control of copper homeostasis cutC - - ko:K06201 - - - - ko00000 - - - CutC k59_1350023_1 1071679.BG57_24040 2.78e-16 77.4 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VJ9X@28216|Betaproteobacteria,1K1D2@119060|Burkholderiaceae 28216|Betaproteobacteria CE Tartrate dehydrogenase ttuC - 1.1.1.83,1.1.1.93,4.1.1.73 ko:K07246 ko00630,ko00650,map00630,map00650 - R00215,R01751,R02545,R06180 RC00084,RC00105,RC00594 ko00000,ko00001,ko01000 - - - Iso_dh k59_1350023_2 1136138.JH604625_gene3485 4.22e-55 181.0 COG0583@1|root,COG0583@2|Bacteria,1MVJ7@1224|Proteobacteria,1RMNJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator dmlR GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006082,GO:0006108,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043436,GO:0043565,GO:0043648,GO:0044237,GO:0044281,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - ko:K16135 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate k59_797768_1 1234364.AMSF01000033_gene346 4.75e-152 438.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,1RMRB@1236|Gammaproteobacteria,1X4CA@135614|Xanthomonadales 135614|Xanthomonadales N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI - - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI k59_797768_2 1234364.AMSF01000033_gene345 1e-40 144.0 COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria,1X4QP@135614|Xanthomonadales 135614|Xanthomonadales MNOU Flagellar rod assembly protein muramidase FlgJ flgJ - - ko:K02395 - - - - ko00000,ko02035 - - - Glucosaminidase,Rod-binding k59_748526_1 1123367.C666_02075 7.83e-13 64.3 COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,2KWVI@206389|Rhodocyclales 206389|Rhodocyclales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese k59_748526_2 748247.AZKH_1002 1.69e-60 187.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria,2KWQT@206389|Rhodocyclales 206389|Rhodocyclales K transcriptional - - - - - - - - - - - - HTH_5 k59_194001_1 1500893.JQNB01000001_gene469 3.94e-124 382.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,1X3CF@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor for ferrienterochelin and colicins - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k59_927134_2 1279009.ADICEAN_00024 7.3e-15 76.6 COG1520@1|root,COG1520@2|Bacteria,4PNAK@976|Bacteroidetes,47YAF@768503|Cytophagia 976|Bacteroidetes S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - - k59_630367_1 1286093.C266_01460 1.94e-33 122.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,1K2NF@119060|Burkholderiaceae 28216|Betaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA k59_630367_2 159087.Daro_3364 4.25e-21 93.2 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,2KV9X@206389|Rhodocyclales 206389|Rhodocyclales F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA k59_894114_1 118168.MC7420_1556 2.19e-47 168.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1G0VR@1117|Cyanobacteria,1H9ZD@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k59_894114_2 118168.MC7420_1541 6.14e-38 131.0 COG0835@1|root,COG0835@2|Bacteria,1G8QF@1117|Cyanobacteria,1HDX0@1150|Oscillatoriales 1117|Cyanobacteria NT CheW-like domain - - - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW k59_1077099_1 1173020.Cha6605_2134 6.44e-12 71.6 COG0455@1|root,COG2199@1|root,COG0455@2|Bacteria,COG3706@2|Bacteria,1G5AU@1117|Cyanobacteria 1117|Cyanobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HisKA,Response_reg k59_243934_1 1523503.JPMY01000037_gene1845 4.19e-76 243.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria 1236|Gammaproteobacteria I acyl-CoA dehydrogenase HA62_19490 - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k59_677092_1 1229909.NSED_08345 1.48e-56 179.0 arCOG04405@1|root,arCOG04405@2157|Archaea 2157|Archaea S ASCH domain - - - - - - - - - - - - ASCH k59_1394266_1 220664.PFL_4016 1.62e-33 118.0 COG3212@1|root,COG3212@2|Bacteria,1NHDB@1224|Proteobacteria,1SH2G@1236|Gammaproteobacteria,1YQW8@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY k59_1394266_2 1294143.H681_13835 3.54e-68 211.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1S0IN@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator IV02_26825 - - - - - - - - - - - Response_reg,Trans_reg_C k59_677129_2 1121020.JIAG01000001_gene990 3.38e-19 89.7 COG0697@1|root,COG0697@2|Bacteria,2IHCX@201174|Actinobacteria 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k59_527238_1 1211777.BN77_p10779 2.71e-147 424.0 COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2TRW7@28211|Alphaproteobacteria,4B8QP@82115|Rhizobiaceae 28211|Alphaproteobacteria C Zinc-binding dehydrogenase - - - ko:K19745 ko00640,ko01100,map00640,map01100 - R00919 RC00095 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k59_527238_2 1218084.BBJK01000101_gene6325 3.33e-09 55.1 COG1733@1|root,COG1733@2|Bacteria,1MZ6G@1224|Proteobacteria,2VUCU@28216|Betaproteobacteria,1K8IZ@119060|Burkholderiaceae 28216|Betaproteobacteria K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR k59_894327_1 436308.Nmar_0714 1.75e-44 159.0 arCOG00373@1|root,arCOG00373@2157|Archaea,41ST8@651137|Thaumarchaeota 651137|Thaumarchaeota L ATPase involved in DNA repair - - - - - - - - - - - - - k59_1176899_1 243233.MCA2420 6.25e-58 202.0 COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1XDMM@135618|Methylococcales 135618|Methylococcales C CoA binding domain - - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig k59_1231402_1 1117647.M5M_09575 2.38e-124 358.0 COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,1J55I@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S amidohydrolase aguB - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase k59_1176910_1 365046.Rta_01830 8.31e-07 51.6 COG1846@1|root,COG1846@2|Bacteria,1RCY7@1224|Proteobacteria,2VSV9@28216|Betaproteobacteria,4AERH@80864|Comamonadaceae 28216|Betaproteobacteria K TIGRFAM homoprotocatechuate degradation operon regulator, HpaR hpaR - - - - - - - - - - - MarR,MarR_2 k59_894403_1 1448139.AI20_17580 8.81e-26 102.0 COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1Y40J@135624|Aeromonadales 135624|Aeromonadales D Part of the ABC transporter FtsEX involved in cellular division ftsX GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0044464,GO:0051301,GO:0071944 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - - k59_939012_2 317013.NY99_11380 2.23e-86 266.0 COG2197@1|root,COG3850@1|root,COG2197@2|Bacteria,COG3850@2|Bacteria,1QU1R@1224|Proteobacteria,1T1MA@1236|Gammaproteobacteria,1X8SH@135614|Xanthomonadales 135614|Xanthomonadales KT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - Cache_3-Cache_2 k59_343566_1 1229909.NSED_03630 4.11e-43 155.0 COG0365@1|root,arCOG01529@2157|Archaea,41S8Z@651137|Thaumarchaeota 651137|Thaumarchaeota I AMP-binding enzyme C-terminal domain - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k59_343566_2 1229909.NSED_03635 5.31e-11 62.4 arCOG05183@1|root,arCOG05183@2157|Archaea 2157|Archaea T PAS domain - - - - - - - - - - - - HATPase_c,HisKA_2,PAS,PAS_4,PAS_9,Response_reg k59_1340407_1 1229909.NSED_08020 3.08e-16 77.0 COG0015@1|root,arCOG01747@2157|Archaea,41SD1@651137|Thaumarchaeota 651137|Thaumarchaeota F adenylosuccinate lyase - - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 k59_986198_1 1163407.UU7_08518 5.45e-181 514.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1X3D1@135614|Xanthomonadales 135614|Xanthomonadales E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind k59_1540719_1 1523503.JPMY01000006_gene2227 3.49e-57 185.0 COG0834@1|root,COG0834@2|Bacteria,1RH2S@1224|Proteobacteria,1S9QV@1236|Gammaproteobacteria 1236|Gammaproteobacteria ET ABC-type amino acid transport signal transduction systems periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 k59_1540719_2 301.JNHE01000028_gene822 1.09e-15 76.3 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1YENE@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 k59_1438799_1 1163409.UUA_17500 9.5e-146 422.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1X3TM@135614|Xanthomonadales 135614|Xanthomonadales H Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control pcnB - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C k59_644237_1 1234364.AMSF01000064_gene2200 1.12e-11 66.2 COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria,1S0MM@1236|Gammaproteobacteria,1X3B4@135614|Xanthomonadales 135614|Xanthomonadales V abc transporter atp-binding protein nodI - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran k59_1092784_2 1452718.JBOY01000026_gene249 1.7e-95 290.0 COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria 1236|Gammaproteobacteria O protease yegQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C k59_1092873_1 136993.KB900626_gene2801 7.84e-09 56.2 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTI9@28211|Alphaproteobacteria,36ZWP@31993|Methylocystaceae 28211|Alphaproteobacteria S Alcohol dehydrogenase GroES-like domain - - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k59_1092873_2 472759.Nhal_2473 2.16e-64 201.0 COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,1S2G2@1236|Gammaproteobacteria,1X0WY@135613|Chromatiales 135613|Chromatiales P Rubrerythrin - - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin k59_1290842_1 1163409.UUA_06204 1.17e-136 403.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1S1KH@1236|Gammaproteobacteria,1X3PX@135614|Xanthomonadales 135614|Xanthomonadales S Glutaryl-7-ACA acylase gaa - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 k59_494574_1 1123020.AUIE01000031_gene2801 3.25e-60 197.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,1RNJJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria ET Belongs to the bacterial solute-binding protein 3 family - - - ko:K02030,ko:K09969 ko02010,map02010 M00232,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 k59_540108_1 1163408.UU9_03472 7.4e-61 193.0 COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1S4U5@1236|Gammaproteobacteria,1X58J@135614|Xanthomonadales 135614|Xanthomonadales T Serine threonine protein phosphatase - - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - PP2C_2 k59_690219_1 925775.XVE_3543 3.64e-74 229.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1X4HS@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt k59_690219_2 1123366.TH3_12600 5.39e-07 50.1 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2U9GC@28211|Alphaproteobacteria,2JTB3@204441|Rhodospirillales 204441|Rhodospirillales H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis - - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 k59_840853_1 1301098.PKB_2614 2.34e-98 298.0 COG3781@1|root,COG3781@2|Bacteria,1MX91@1224|Proteobacteria,1S0QU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane - - - ko:K08994 - - - - ko00000,ko02000 1.A.46.2 - - Bestrophin k59_1093157_1 1224318.DT73_02055 6.74e-42 155.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - - - - - - - - - - Cache_3-Cache_2,HAMP,MCPsignal k59_494668_1 1234364.AMSF01000095_gene2566 8.67e-35 122.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1X6XR@135614|Xanthomonadales 135614|Xanthomonadales S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 k59_494668_2 1234364.AMSF01000095_gene2565 1.56e-43 149.0 COG0614@1|root,COG0614@2|Bacteria,1PK1A@1224|Proteobacteria,1RRDK@1236|Gammaproteobacteria,1X3UZ@135614|Xanthomonadales 135614|Xanthomonadales P ABC transporter substrate-binding protein - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 k59_1541108_1 1163408.UU9_09662 5.12e-99 310.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1X5GN@135614|Xanthomonadales 135614|Xanthomonadales KL DNA helicase dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - Helicase_C_2,ResIII k59_1439187_1 1163409.UUA_02291 8.68e-53 188.0 COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1X41H@135614|Xanthomonadales 135614|Xanthomonadales S Pathogenicity protein - - - ko:K09800 - - - - ko00000,ko02000 - - - TamB k59_494976_1 1500893.JQNB01000001_gene295 8.02e-51 170.0 COG3064@1|root,COG3064@2|Bacteria,1NDEI@1224|Proteobacteria,1T5E4@1236|Gammaproteobacteria,1XCV2@135614|Xanthomonadales 135614|Xanthomonadales M TonB C terminal - - - - - - - - - - - - TonB_2 k59_494976_2 1234364.AMSF01000024_gene3811 4.21e-40 145.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1X3CZ@135614|Xanthomonadales 135614|Xanthomonadales U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N k59_1093539_1 1439940.BAY1663_04176 1.02e-25 103.0 2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,1RNIA@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Alginate export - - - - - - - - - - - - Alginate_exp k59_1291318_1 1000565.METUNv1_02457 2.24e-69 226.0 COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,2KVJ8@206389|Rhodocyclales 206389|Rhodocyclales T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - 3.1.4.17 ko:K01120 ko00230,map00230 - R00191,R01234 RC00296 ko00000,ko00001,ko01000 - - - FHA,GAF,HD,HD_5 k59_739530_1 477228.YO5_11470 1.84e-40 135.0 COG4519@1|root,COG4519@2|Bacteria,1N38K@1224|Proteobacteria,1SENE@1236|Gammaproteobacteria,1Z34S@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - HTH_43 k59_739530_2 1499686.BN1079_02556 1.07e-12 63.9 COG1585@1|root,COG1585@2|Bacteria,1N4FG@1224|Proteobacteria,1S4V9@1236|Gammaproteobacteria 1236|Gammaproteobacteria OU COG1585 Membrane protein implicated in regulation of membrane protease activity - - - ko:K07340 - - - - ko00000 - - - NfeD k59_645133_1 1229909.NSED_00270 5.57e-111 323.0 COG1378@1|root,arCOG02038@2157|Archaea,41SFR@651137|Thaumarchaeota 651137|Thaumarchaeota K Archaeal transcriptional regulator TrmB - - - - - - - - - - - - Regulator_TrmB,TrmB k59_1491518_1 863365.XHC_3194 1.65e-77 258.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1X3B5@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_939912_2 765910.MARPU_14030 2.85e-35 130.0 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1WW5P@135613|Chromatiales 135613|Chromatiales J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k59_540665_1 1234364.AMSF01000027_gene3465 2.74e-108 316.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1X34H@135614|Xanthomonadales 135614|Xanthomonadales E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 k59_645220_1 69328.PVLB_14335 6.29e-13 65.5 COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,1S4E9@1236|Gammaproteobacteria 1236|Gammaproteobacteria J ribosomal large subunit export from nucleus - - - - - - - - - - - - NMD3 k59_645220_2 32042.PstZobell_13976 5.46e-60 189.0 COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RP3P@1236|Gammaproteobacteria,1Z2MG@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - - - - - - - - - - NLPC_P60 k59_690789_1 745411.B3C1_18346 1.65e-66 204.0 COG2888@1|root,COG2888@2|Bacteria,1P9T7@1224|Proteobacteria,1RYIB@1236|Gammaproteobacteria,1JBAW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Zinc-ribbon containing domain ybeL - - - - - - - - - - - DUF1451 k59_690789_2 745411.B3C1_18341 4.48e-26 105.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1J4WW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - ko:K03820 - - - - ko00000,ko01000 - GT2 iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590 CN_hydrolase k59_1341447_1 1234364.AMSF01000063_gene2232 1.27e-32 125.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1X479@135614|Xanthomonadales 135614|Xanthomonadales M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H k59_384686_1 1163409.UUA_14459 2.11e-92 275.0 COG2802@1|root,COG2802@2|Bacteria,1N54S@1224|Proteobacteria,1T15D@1236|Gammaproteobacteria,1XD34@135614|Xanthomonadales 135614|Xanthomonadales S to the N-terminal domain of Lon protease - - - - - - - - - - - - LON_substr_bdg k59_91308_1 1500893.JQNB01000001_gene1404 2.43e-104 318.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1X3MV@135614|Xanthomonadales 135614|Xanthomonadales C dehydrogenase lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim k59_841538_1 326442.PSHAa2632 9.92e-48 172.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,2PZFE@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264 - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - iG2583_1286.G2583_0058 OstA,OstA_C k59_1291766_1 1163409.UUA_03208 2.63e-62 208.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1PJGX@1224|Proteobacteria,1SMIB@1236|Gammaproteobacteria,1X3BG@135614|Xanthomonadales 135614|Xanthomonadales M Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT k59_790088_1 1195246.AGRI_02328 1.68e-106 320.0 COG1431@1|root,COG1431@2|Bacteria,1R5TD@1224|Proteobacteria,1TA6P@1236|Gammaproteobacteria,46BG5@72275|Alteromonadaceae 1236|Gammaproteobacteria J Piwi - - - - - - - - - - - - - k59_1492130_1 1100720.ALKN01000018_gene1742 7.51e-11 65.5 28HHC@1|root,2Z7T2@2|Bacteria,1PZ57@1224|Proteobacteria 1224|Proteobacteria S AAA domain - - - - - - - - - - - - AAA_24 k59_691151_1 1515746.HR45_02540 5.64e-89 279.0 COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RZ70@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protease with the C-terminal PDZ domain - - - - - - - - - - - - Peptidase_M61,TPR_3 k59_841732_1 485917.Phep_2703 1.22e-48 175.0 COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IQXW@117747|Sphingobacteriia 976|Bacteroidetes G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos k59_1041066_2 745411.B3C1_02535 9.58e-25 102.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1J4R4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII k59_440024_1 745411.B3C1_12954 2.03e-125 364.0 COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,1RMF1@1236|Gammaproteobacteria,1J511@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the agmatine deiminase family aguA - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph k59_940423_1 436308.Nmar_0450 8.29e-65 202.0 COG1676@1|root,arCOG01701@2157|Archaea,41SJY@651137|Thaumarchaeota 651137|Thaumarchaeota L tRNA intron endonuclease, N-terminal domain - - 4.6.1.16 ko:K01170 - - - - ko00000,ko01000,ko03016 - - - tRNA_int_endo,tRNA_int_endo_N k59_987399_1 1071679.BG57_10690 7.58e-29 115.0 COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,2VK42@28216|Betaproteobacteria,1K50W@119060|Burkholderiaceae 28216|Betaproteobacteria S Fusaric acid resistance protein conserved region aaeB - - - - - - - - - - - FUSC k59_987399_2 1523503.JPMY01000041_gene412 7.58e-25 98.6 COG1846@1|root,COG1846@2|Bacteria,1N19E@1224|Proteobacteria,1S6YD@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - ko:K06075 - - - - ko00000,ko03000 - - - HTH_27,MarR,MarR_2 k59_1492427_1 748280.NH8B_2766 2.54e-112 359.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2VI8X@28216|Betaproteobacteria 28216|Betaproteobacteria L DEAD DEAH box helicase lhr - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C k59_496024_1 745411.B3C1_04850 1.99e-10 62.4 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,1J59B@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG1629 Outer membrane receptor proteins, mostly Fe transport - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_91776_1 1453503.AU05_19690 7.29e-127 382.0 COG0404@1|root,COG3665@1|root,COG0404@2|Bacteria,COG3665@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1YI61@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Domain of unknown function (DUF1989) - - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - DUF1989,GCV_T,GCV_T_C k59_1492568_1 1133849.O3I_014000 8.59e-13 72.0 COG0796@1|root,COG0796@2|Bacteria,2H4W6@201174|Actinobacteria 201174|Actinobacteria M Provides the (R)-glutamate required for cell wall biosynthesis - - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race k59_1492568_2 1229909.NSED_09925 9.45e-11 60.8 COG2875@1|root,arCOG00645@2157|Archaea,41SE7@651137|Thaumarchaeota 651137|Thaumarchaeota H Tetrapyrrole (Corrin/Porphyrin) Methylases - - 2.1.1.133,2.1.1.271 ko:K05936 ko00860,ko01100,map00860,map01100 - R05181,R05810 RC00003,RC01294,RC02049 ko00000,ko00001,ko01000 - - - TP_methylase k59_1041350_1 391589.RGAI101_4139 2.73e-88 269.0 COG0683@1|root,COG0683@2|Bacteria,1MWH7@1224|Proteobacteria,2TS8K@28211|Alphaproteobacteria 28211|Alphaproteobacteria E branched-chain amino acid - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k59_1101575_2 1234364.AMSF01000072_gene1815 6.26e-46 162.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RSG9@1236|Gammaproteobacteria,1X3F8@135614|Xanthomonadales 135614|Xanthomonadales E aminopeptidase pepN - - - - - - - - - - - Leuk-A4-hydro_C,Peptidase_M1 k59_1501988_1 1234364.AMSF01000036_gene231 1.38e-68 226.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,1XCDT@135614|Xanthomonadales 1236|Gammaproteobacteria T diguanylate cyclase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,CHASE4,GGDEF,PAS_9 k59_651260_1 745411.B3C1_11964 5.01e-44 152.0 COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,1J5KW@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases yhdH - - ko:K19745 ko00640,ko01100,map00640,map01100 - R00919 RC00095 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k59_651260_2 1005048.CFU_0019 7.01e-21 87.8 COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,2VTM1@28216|Betaproteobacteria,477P4@75682|Oxalobacteraceae 28216|Betaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family tpm - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT k59_1401940_1 1312959.KI914647_gene194 2.48e-41 147.0 COG3677@1|root,COG3677@2|Bacteria,2IF2C@201174|Actinobacteria 201174|Actinobacteria L ISXO2-like transposase domain - - - - - - - - - - - - DDE_Tnp_IS1595,Zn_Tnp_IS1595 k59_1401955_1 1500893.JQNB01000001_gene1946 1.42e-72 231.0 COG3669@1|root,COG3669@2|Bacteria,1R6V7@1224|Proteobacteria,1RWFD@1236|Gammaproteobacteria,1X3J1@135614|Xanthomonadales 135614|Xanthomonadales G alpha-l-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,F5_F8_type_C k59_1401955_2 1123073.KB899241_gene2044 3.53e-33 129.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,1X5QY@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor - - - - - - - - - - - - CarboxypepD_reg k59_1352679_1 1121904.ARBP01000003_gene6447 5.11e-16 76.6 COG1988@1|root,COG1988@2|Bacteria,4NPMW@976|Bacteroidetes,47VIF@768503|Cytophagia 976|Bacteroidetes S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM k59_101933_1 1163407.UU7_01267 7.52e-77 251.0 COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,1RN3C@1236|Gammaproteobacteria,1X38Y@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - ko:K16090 - - - - ko00000,ko02000 1.B.14.1.11 - - Plug,TonB_dep_Rec k59_202011_1 283699.D172_4058 1.02e-24 94.7 2E8WW@1|root,33371@2|Bacteria,1NFIU@1224|Proteobacteria,1SDAW@1236|Gammaproteobacteria,2Q4XT@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_152013_2 379731.PST_2520 1.07e-69 222.0 COG4591@1|root,COG4591@2|Bacteria,1Q2BY@1224|Proteobacteria,1RY89@1236|Gammaproteobacteria,1YZTD@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M ABC-type transport system, involved in lipoprotein release, permease component - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD k59_152032_1 1234364.AMSF01000085_gene2958 5.51e-114 338.0 COG0668@1|root,COG0668@2|Bacteria,1MVX9@1224|Proteobacteria,1RNBM@1236|Gammaproteobacteria,1X4IC@135614|Xanthomonadales 135614|Xanthomonadales M mechanosensitive ion channel - - - ko:K16053 - - - - ko00000,ko02000 1.A.23.4.5 - - MS_channel k59_951631_1 228410.NE0625 8.84e-112 342.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,372I1@32003|Nitrosomonadales 28216|Betaproteobacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind k59_501261_1 1000565.METUNv1_02088 2.13e-133 387.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria,2KV6W@206389|Rhodocyclales 206389|Rhodocyclales C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k59_951677_1 743720.Psefu_3261 3.41e-88 280.0 COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1YV9C@136845|Pseudomonas putida group 1236|Gammaproteobacteria V Type I secretion system lapB - - ko:K12541 ko02010,map02010 M00330 - - ko00000,ko00001,ko00002,ko02000,ko02044 3.A.1.109.3,3.A.1.109.4 - - ABC_membrane,ABC_tran,Peptidase_C39 k59_401335_1 1121447.JONL01000008_gene3585 3.67e-06 50.1 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,42QYE@68525|delta/epsilon subdivisions,2X5HW@28221|Deltaproteobacteria,2MGRC@213115|Desulfovibrionales 28221|Deltaproteobacteria S WLM domain - - - ko:K07043 - - - - ko00000 - - - DUF45 k59_401335_2 1033740.CAEW01000028_gene2665 1.77e-07 52.8 COG0084@1|root,COG0084@2|Bacteria,1TQRF@1239|Firmicutes,4HDI4@91061|Bacilli,26GQQ@186818|Planococcaceae 91061|Bacilli L TatD related DNase mttC - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase k59_801531_1 1168478.I6R9L7_9CAUD 2.84e-20 85.9 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QKMP@10699|Siphoviridae 10699|Siphoviridae S ERF superfamily - - - - - - - - - - - - - k59_1559675_1 359.CN09_09185 2.22e-65 215.0 28JKG@1|root,2Z9DB@2|Bacteria,1NMKD@1224|Proteobacteria,2URH0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3383) - - - - - - - - - - - - DUF3383 k59_108858_1 1540221.JQNI01000002_gene2003 2.9e-99 323.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1WIA7@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E PFAM Conserved region in glutamate synthase - - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase k59_259077_1 288000.BBta_2279 2.55e-104 309.0 COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,2TRUA@28211|Alphaproteobacteria,3JXDV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Serine aminopeptidase, S33 - - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1 k59_755065_1 1005048.CFU_2455 5.05e-16 77.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,472KY@75682|Oxalobacteraceae 28216|Betaproteobacteria S Domain of unknown function (DUF1732) yicC - - - - - - - - - - - DUF1732,YicC_N k59_755065_2 1120999.JONM01000006_gene2459 1.55e-49 167.0 COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria,2KQP9@206351|Neisseriales 206351|Neisseriales KLT Protein tyrosine kinase - - - - - - - - - - - - MORN,Pkinase k59_1305079_1 1411123.JQNH01000001_gene2693 6.36e-76 234.0 COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2TQUC@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the UPF0271 (lamB) family ybgL - - ko:K07160 - - - - ko00000 - - - LamB_YcsF k59_1456380_1 1234364.AMSF01000025_gene3675 2.2e-70 233.0 arCOG05967@1|root,2Z8PR@2|Bacteria,1QSXZ@1224|Proteobacteria,1RWJW@1236|Gammaproteobacteria,1X3YX@135614|Xanthomonadales 135614|Xanthomonadales S Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A - - - - - - - - - - - - PNGaseA k59_159099_2 1500893.JQNB01000001_gene3578 1.16e-87 277.0 COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,1X4WM@135614|Xanthomonadales 135614|Xanthomonadales V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k59_905262_1 95619.PM1_0229000 2.72e-42 150.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria 1236|Gammaproteobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_1359985_1 1234364.AMSF01000017_gene1427 7.96e-156 446.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1X4J9@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 k59_1560062_1 349966.DJ58_2728 2.47e-16 86.7 COG5301@1|root,COG5301@2|Bacteria,1MWNN@1224|Proteobacteria,1RR74@1236|Gammaproteobacteria,41FZI@629|Yersinia 1236|Gammaproteobacteria S Phage tail fibre repeat - - - - - - - - - - - - Collar,DUF3751,Phage_fiber_2 k59_1456529_1 1131266.ARWQ01000010_gene32 9.54e-27 104.0 arCOG08734@1|root,arCOG08734@2157|Archaea,41SP9@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_1456529_2 436308.Nmar_0469 6.73e-31 112.0 arCOG10527@1|root,arCOG10527@2157|Archaea,41SPB@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_109378_1 243233.MCA0335 4.14e-85 280.0 COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1PE6F@1224|Proteobacteria,1RWQP@1236|Gammaproteobacteria,1XDNM@135618|Methylococcales 135618|Methylococcales CEH 2 iron, 2 sulfur cluster binding - - - - - - - - - - - - Pyr_redox_2 k59_1305214_1 358220.C380_17230 1.2e-18 90.1 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,4ABJ6@80864|Comamonadaceae 28216|Betaproteobacteria NU Tfp pilus assembly protein tip-associated adhesin PilY1-like protein pilY - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k59_504704_1 748247.AZKH_4274 2.79e-117 343.0 COG2730@1|root,COG2730@2|Bacteria,1PJTY@1224|Proteobacteria,2VK6E@28216|Betaproteobacteria,2KVYT@206389|Rhodocyclales 206389|Rhodocyclales G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - 3.2.1.58 ko:K01210 ko00500,map00500 - R00308,R03115 RC00467 ko00000,ko00001,ko01000 - - - Cellulase k59_54963_1 243265.plu2750 2.93e-08 60.5 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state bepA GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - Peptidase_M48,TPR_19 k59_1205917_1 1229909.NSED_09760 1.86e-48 161.0 COG0483@1|root,arCOG01349@2157|Archaea,41T8P@651137|Thaumarchaeota 651137|Thaumarchaeota G Inositol monophosphatase - - 3.1.3.25,3.1.3.7 ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 M00131 R00188,R00508,R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000,ko03016 - - - Inositol_P k59_1205917_2 1229909.NSED_09755 1.73e-53 171.0 COG0529@1|root,arCOG01040@2157|Archaea 2157|Archaea F Catalyzes the synthesis of activated sulfate cysC - 2.7.1.25 ko:K00860,ko:K07028 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R04928 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - AAA_33,APS_kinase k59_55036_1 388051.AUFE01000012_gene2942 9.46e-52 169.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR7N@28216|Betaproteobacteria,1KH6M@119060|Burkholderiaceae 28216|Betaproteobacteria U general secretion pathway protein G gspG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG k59_755319_1 330214.NIDE0561 1.62e-124 366.0 COG0535@1|root,COG0535@2|Bacteria,3J10V@40117|Nitrospirae 40117|Nitrospirae C Iron-sulfur cluster-binding domain - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM k59_1205948_1 1699360.A0A0K1YZY7_CVHSA 4.86e-113 361.0 4QAM0@10239|Viruses,4R10Q@439488|ssRNA viruses,4R0QR@35278|ssRNA positive-strand viruses no DNA stage,4R1N0@76804|Nidovirales 76804|Nidovirales A omega peptidase activity - GO:0000175,GO:0001172,GO:0001510,GO:0001959,GO:0001960,GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003727,GO:0003824,GO:0003968,GO:0004386,GO:0004482,GO:0004483,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006370,GO:0006396,GO:0006397,GO:0006417,GO:0006464,GO:0006508,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008171,GO:0008173,GO:0008174,GO:0008408,GO:0008757,GO:0009058,GO:0009059,GO:0009451,GO:0009452,GO:0009605,GO:0009607,GO:0009889,GO:0009892,GO:0009893,GO:0009894,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010506,GO:0010556,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0010646,GO:0010648,GO:0010952,GO:0016032,GO:0016070,GO:0016071,GO:0016462,GO:0016556,GO:0016579,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0018130,GO:0018995,GO:0019048,GO:0019049,GO:0019054,GO:0019056,GO:0019057,GO:0019058,GO:0019079,GO:0019080,GO:0019083,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0020012,GO:0023051,GO:0023057,GO:0030162,GO:0030430,GO:0030682,GO:0030683,GO:0031323,GO:0031325,GO:0031326,GO:0031329,GO:0031347,GO:0031348,GO:0032259,GO:0032268,GO:0032270,GO:0032774,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0034062,GO:0034248,GO:0034641,GO:0034654,GO:0035821,GO:0036211,GO:0036260,GO:0036265,GO:0039502,GO:0039503,GO:0039506,GO:0039507,GO:0039519,GO:0039548,GO:0039579,GO:0039604,GO:0039644,GO:0039648,GO:0039653,GO:0039656,GO:0039657,GO:0039690,GO:0039694,GO:0039713,GO:0039714,GO:0042025,GO:0042802,GO:0043085,GO:0043170,GO:0043207,GO:0043412,GO:0043414,GO:0043656,GO:0043657,GO:0044003,GO:0044068,GO:0044073,GO:0044092,GO:0044093,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044279,GO:0044359,GO:0044362,GO:0044403,GO:0044413,GO:0044414,GO:0044415,GO:0044419,GO:0044501,GO:0045088,GO:0045824,GO:0045862,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050690,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051336,GO:0051345,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051817,GO:0051832,GO:0051833,GO:0051834,GO:0052026,GO:0052027,GO:0052029,GO:0052031,GO:0052037,GO:0052055,GO:0052056,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052204,GO:0052205,GO:0052250,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052312,GO:0052493,GO:0052547,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0060338,GO:0060339,GO:0060759,GO:0060761,GO:0065007,GO:0065009,GO:0070536,GO:0070646,GO:0070647,GO:0071108,GO:0071704,GO:0075109,GO:0075111,GO:0075112,GO:0075114,GO:0075136,GO:0075528,GO:0080009,GO:0080090,GO:0080134,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097659,GO:0097747,GO:0101005,GO:0106005,GO:0140096,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1990380,GO:2000112,GO:2000152,GO:2000158,GO:2001141 - - - - - - - - - - - k59_555270_4 269482.Bcep1808_1314 6.02e-59 188.0 COG4678@1|root,COG4678@2|Bacteria,1R92U@1224|Proteobacteria,2VUZ6@28216|Betaproteobacteria,1KDHZ@119060|Burkholderiaceae 28216|Betaproteobacteria G PFAM glycoside hydrolase family 24 - - - - - - - - - - - - Phage_lysozyme k59_955735_1 1448139.AI20_17890 2.69e-53 168.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,1Y4ID@135624|Aeromonadales 135624|Aeromonadales J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV - - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 k59_955735_2 1448139.AI20_17885 1.43e-52 170.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1Y465@135624|Aeromonadales 135624|Aeromonadales J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC - - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C k59_1456804_1 1229909.NSED_08125 1.22e-71 224.0 COG0506@1|root,arCOG06322@2157|Archaea,41SY1@651137|Thaumarchaeota 651137|Thaumarchaeota E Proline dehydrogenase - - - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh k59_1456804_2 1229909.NSED_08130 4.16e-20 88.6 COG1012@1|root,arCOG01252@2157|Archaea,41T12@651137|Thaumarchaeota 651137|Thaumarchaeota C Aldehyde dehydrogenase family - - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - - Aldedh k59_1406817_1 1304883.KI912532_gene1621 2.35e-108 329.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,2KVV7@206389|Rhodocyclales 206389|Rhodocyclales J glutaminyl-tRNA glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C k59_109800_1 71139.XP_010046011.1 1.04e-83 259.0 KOG4853@1|root,KOG4853@2759|Eukaryota,37UN2@33090|Viridiplantae,3GY4V@35493|Streptophyta 35493|Streptophyta S mitotic sister chromatid biorientation - - - - - - - - - - - - - k59_109807_1 1500893.JQNB01000001_gene1095 3.44e-12 67.4 COG1629@1|root,COG4772@1|root,COG4771@2|Bacteria,COG4772@2|Bacteria,1MWZ7@1224|Proteobacteria,1T8D8@1236|Gammaproteobacteria,1X4GR@135614|Xanthomonadales 135614|Xanthomonadales P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k59_705487_1 330214.NIDE0031 1.69e-42 152.0 COG1566@1|root,COG1566@2|Bacteria,3J0TB@40117|Nitrospirae 40117|Nitrospirae V HlyD family secretion protein - - - ko:K01993 - - - - ko00000 - - - HlyD_D23 k59_504923_1 1041146.ATZB01000015_gene1691 3.53e-74 233.0 COG1638@1|root,COG1638@2|Bacteria,1MWAW@1224|Proteobacteria,2TV91@28211|Alphaproteobacteria,4BI91@82115|Rhizobiaceae 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 MA20_30160 - - - - - - - - - - - DctP k59_1305437_1 1452718.JBOY01000078_gene453 1.5e-117 339.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 k59_655058_1 1500890.JQNL01000001_gene2240 1.29e-24 105.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,1X3CF@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor for ferrienterochelin and colicins - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k59_1560722_3 1380394.JADL01000008_gene3764 4.41e-14 72.0 28PTM@1|root,2ZCEU@2|Bacteria,1R5DD@1224|Proteobacteria,2TVG7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Family of unknown function (DUF5309) - - - - - - - - - - - - DUF5309 k59_705527_1 1382306.JNIM01000001_gene3821 1.81e-12 73.2 COG2239@1|root,COG2239@2|Bacteria,2G6H7@200795|Chloroflexi 200795|Chloroflexi P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k59_305599_1 95619.PM1_0210830 2.56e-91 283.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Belongs to the ABC transporter superfamily yejF GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K13896 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY k59_705538_1 1163408.UU9_10262 4.52e-115 338.0 COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,1X3UT@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily adhC - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N k59_824723_1 1234364.AMSF01000015_gene3174 1.45e-95 287.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1X44P@135614|Xanthomonadales 135614|Xanthomonadales K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg k59_1227475_1 159087.Daro_3280 1.9e-91 285.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,2KV11@206389|Rhodocyclales 206389|Rhodocyclales U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD-TM1,SecD_SecF,Sec_GG k59_1274861_1 243233.MCA0087 1.62e-37 144.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,1XDKW@135618|Methylococcales 135618|Methylococcales NU Neisseria PilC beta-propeller domain - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC k59_1389783_1 1234364.AMSF01000072_gene1799 1.12e-09 63.2 COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,1RMJ4@1236|Gammaproteobacteria,1X44G@135614|Xanthomonadales 135614|Xanthomonadales S Fusaric acid resistance protein-like - - - - - - - - - - - - FUSC k59_1389783_2 1177179.A11A3_13815 2.33e-15 69.7 2EGFD@1|root,33A7D@2|Bacteria,1NH03@1224|Proteobacteria,1SHJZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1656) - - - - - - - - - - - - DUF1656 k59_369753_1 76114.ebA4737 1.83e-37 138.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,2KV7J@206389|Rhodocyclales 206389|Rhodocyclales C glycolate oxidase subunit GlcD - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4 k59_1589847_2 1429851.X548_09280 3.07e-62 198.0 COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,1X449@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1365) - - - ko:K09701 - - - - ko00000 - - - DUF1365 k59_1274913_1 1123060.JONP01000009_gene1973 4.26e-20 89.7 COG4129@1|root,COG4129@2|Bacteria,1NBDD@1224|Proteobacteria 1224|Proteobacteria S Aromatic acid exporter family member 1 - - - - - - - - - - - - FUSC_2 k59_673829_1 436308.Nmar_1690 3.1e-108 323.0 COG1156@1|root,arCOG00865@2157|Archaea,41SPY@651137|Thaumarchaeota 651137|Thaumarchaeota C Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit atpB - - ko:K02118 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_ab,ATP-synt_ab_N k59_289654_1 1500890.JQNL01000001_gene2124 8.86e-71 218.0 COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,1RZ28@1236|Gammaproteobacteria,1XC5I@135614|Xanthomonadales 135614|Xanthomonadales O Redoxin - - - - - - - - - - - - AhpC-TSA k59_289654_2 1232683.ADIMK_0409 4.67e-62 196.0 COG1024@1|root,COG1024@2|Bacteria,1Q51H@1224|Proteobacteria,1S1RV@1236|Gammaproteobacteria,46BKD@72275|Alteromonadaceae 1236|Gammaproteobacteria I Enoyl-CoA hydratase/isomerase - - 3.7.1.18 ko:K20765 - - - - ko00000,ko01000 - - - ECH_1 k59_1125323_1 497321.C664_07713 2.39e-45 154.0 COG1024@1|root,COG1024@2|Bacteria,1R3U7@1224|Proteobacteria,2VMC4@28216|Betaproteobacteria 28216|Betaproteobacteria I Enoyl-CoA hydratase - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 k59_1125323_2 1144325.PMI22_05205 5.94e-44 152.0 COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,1RPZN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 2-nitropropane dioxygenase - - 1.13.12.16,1.3.1.9 ko:K00459,ko:K02371 ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212 M00083 R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076,RC02541,RC02759 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO k59_1073844_1 745411.B3C1_00550 1.69e-21 92.4 COG4776@1|root,COG4776@2|Bacteria,1P563@1224|Proteobacteria,1RP5G@1236|Gammaproteobacteria,1JC3Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction rnb GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0008859,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.1.13.1 ko:K01147 - - - - ko00000,ko01000,ko03016 - - - OB_RNB,RNB,S1 k59_1073844_2 401053.AciPR4_0633 2.48e-33 124.0 COG2207@1|root,COG2207@2|Bacteria,3Y34X@57723|Acidobacteria,2JKM9@204432|Acidobacteriia 204432|Acidobacteriia K transcriptional regulator, AraC - - - - - - - - - - - - Cupin_6,HTH_18,HTH_AraC k59_1474877_1 1234364.AMSF01000088_gene2733 4.9e-106 322.0 COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,1X37B@135614|Xanthomonadales 135614|Xanthomonadales G PQQ-like domain mxaF - - - - - - - - - - - PQQ k59_1227639_2 525897.Dbac_0094 1.12e-48 171.0 COG2865@1|root,COG2865@2|Bacteria,1MXG1@1224|Proteobacteria,42MIK@68525|delta/epsilon subdivisions,2WISD@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Putative ATP-dependent DNA helicase recG C-terminal - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,HATPase_c_4 k59_1590039_1 1229909.NSED_00835 1.74e-119 354.0 COG2368@1|root,arCOG02143@2157|Archaea,41SA0@651137|Thaumarchaeota 651137|Thaumarchaeota Q Vinylacetyl-CoA Delta-isomerase - - 4.2.1.120,5.3.3.3 ko:K14534 ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200 M00374,M00375 R03031,R10782 RC01857,RC03277 ko00000,ko00001,ko00002,ko01000 - - - HpaB,HpaB_N k59_824959_1 1234364.AMSF01000032_gene3360 5.17e-102 307.0 COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,1RP7V@1236|Gammaproteobacteria,1X42N@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 k59_25667_1 1082933.MEA186_06086 1.29e-32 129.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1R20U@1224|Proteobacteria,2U3F2@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_6 k59_381434_1 395965.Msil_1721 1.19e-18 86.7 COG0500@1|root,COG2226@2|Bacteria,1RB4F@1224|Proteobacteria,2U613@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_23,Methyltransf_25,Ubie_methyltran k59_838615_1 391038.Bphy_5483 1.12e-15 72.0 2C91B@1|root,33D4Z@2|Bacteria,1N875@1224|Proteobacteria,2W5BB@28216|Betaproteobacteria,1KAAY@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_838615_2 1123008.KB905696_gene2994 9.64e-06 46.2 COG1652@1|root,COG1652@2|Bacteria,4PKGU@976|Bacteroidetes,2G3GV@200643|Bacteroidia,231NK@171551|Porphyromonadaceae 976|Bacteroidetes S LysM domain - - - - - - - - - - - - - k59_687898_1 322710.Avin_25380 2.74e-94 298.0 COG1752@1|root,COG1752@2|Bacteria,1MWH2@1224|Proteobacteria,1SISW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3376) - - - - - - - - - - - - DUF3376,Patatin k59_1538897_1 948106.AWZT01000033_gene1637 2.89e-07 50.1 COG0346@1|root,COG0346@2|Bacteria,1MZ2H@1224|Proteobacteria,2VSUN@28216|Betaproteobacteria,1K8K7@119060|Burkholderiaceae 28216|Betaproteobacteria E lactoylglutathione lyase activity - - - - - - - - - - - - - k59_1538897_2 1234364.AMSF01000013_gene673 3.47e-139 413.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1X45G@135614|Xanthomonadales 135614|Xanthomonadales E Acetolactate synthase - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k59_492086_1 557598.LHK_00649 2.42e-57 193.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2VJK0@28216|Betaproteobacteria,2KQEG@206351|Neisseriales 206351|Neisseriales C Malate synthase aceB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase k59_492086_2 504832.OCAR_4715 2.57e-37 135.0 COG1893@1|root,COG1893@2|Bacteria,1QMH8@1224|Proteobacteria,2TSGW@28211|Alphaproteobacteria,3K2T7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - - k59_587249_1 1234364.AMSF01000061_gene2094 6.73e-17 74.7 2AQAS@1|root,31FGS@2|Bacteria,1QD17@1224|Proteobacteria,1T8VU@1236|Gammaproteobacteria,1XBAX@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_838756_1 1163409.UUA_13370 9.9e-125 387.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X4NP@135614|Xanthomonadales 135614|Xanthomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07789 ko02020,map02020 M00648 - - ko00000,ko00001,ko00002,ko02000 2.A.6.2 - - ACR_tran k59_787269_2 95619.PM1_0213875 4.19e-44 149.0 COG1028@1|root,COG1028@2|Bacteria,1R756@1224|Proteobacteria,1SNFS@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 k59_1038041_1 1121035.AUCH01000008_gene1117 2.65e-20 89.7 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,2KVC9@206389|Rhodocyclales 206389|Rhodocyclales E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC k59_1038041_2 1163617.SCD_n00016 7.02e-47 157.0 COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria 28216|Betaproteobacteria NU NYN domain - - - - - - - - - - - - NYN,OST-HTH k59_1243158_1 445685.E3SKH9_9CAUD 2.29e-27 113.0 4QAIK@10239|Viruses,4QUPH@35237|dsDNA viruses no RNA stage,4QPEB@28883|Caudovirales,4QHXI@10662|Myoviridae 10662|Myoviridae S hydrolase activity - - - - - - - - - - - - - k59_437128_1 666685.R2APBS1_1811 8.81e-130 382.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1X3UC@135614|Xanthomonadales 135614|Xanthomonadales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k59_492395_1 287.DR97_4112 2.45e-42 154.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1YDI3@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria F Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 AIRS_C,GATase_5 k59_492395_2 1109445.AGSX01000107_gene1259 5.96e-11 62.8 COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1YZRR@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella mltF GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K18691 - - - - ko00000,ko01000,ko01011 - - iBWG_1329.BWG_2322,iEC042_1314.EC042_2762,iECDH1ME8569_1439.ECDH1ME8569_2485,iECNA114_1301.ECNA114_2631,iECP_1309.ECP_2560,iECSF_1327.ECSF_2397,iECW_1372.ECW_m2786,iEKO11_1354.EKO11_1175,iEcDH1_1363.EcDH1_1110,iEcHS_1320.EcHS_A2711,iEcolC_1368.EcolC_1119,iG2583_1286.G2583_3089,iJO1366.b2558,iSFxv_1172.SFxv_2861,iUMN146_1321.UM146_03930,iUMNK88_1353.UMNK88_3212,iUTI89_1310.UTI89_C2878,iWFL_1372.ECW_m2786,iY75_1357.Y75_RS13345 SBP_bac_3,SLT k59_642397_1 592316.Pat9b_2427 6.96e-50 171.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,1RY4Q@1236|Gammaproteobacteria,3W1XD@53335|Pantoea 1236|Gammaproteobacteria H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD k59_642397_2 1005994.GTGU_02873 2.43e-10 60.8 COG1811@1|root,COG1811@2|Bacteria,1MX1D@1224|Proteobacteria,1RYSH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Membrane yqgA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07150 - - - - ko00000 - - - DUF554 k59_492428_1 745411.B3C1_02570 1.33e-32 125.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,1J4C4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 Meth_synt_1,Meth_synt_2 k59_492428_2 745411.B3C1_02565 5.82e-36 134.0 COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1J4Q9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E homoserine dehydrogenase hom - 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 k59_1437288_1 1278308.KB907078_gene2008 4.28e-19 84.7 COG2159@1|root,COG2159@2|Bacteria,2HEB4@201174|Actinobacteria,4FN73@85023|Microbacteriaceae 201174|Actinobacteria S Amidohydrolase - - 4.1.1.103,4.1.1.45,4.1.1.46,4.1.1.52 ko:K03392,ko:K07045,ko:K14333,ko:K20941,ko:K22213 ko00362,ko00380,ko00627,ko01100,ko01120,map00362,map00380,map00627,map01100,map01120 M00038 R00821,R04323,R11353 RC00390,RC00569,RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 k59_538307_1 1118235.CAJH01000018_gene1012 7.61e-218 629.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1X35C@135614|Xanthomonadales 135614|Xanthomonadales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k59_587677_1 644801.Psest_0013 6.08e-104 306.0 COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,1RRRE@1236|Gammaproteobacteria,1Z1PD@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M COG1560 Lauroyl myristoyl acyltransferase htrB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans k59_688497_1 318996.AXAZ01000001_gene4572 5.34e-78 246.0 COG1804@1|root,COG1804@2|Bacteria,1MU5U@1224|Proteobacteria,2TRIZ@28211|Alphaproteobacteria,3JQU6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 k59_88934_1 1163408.UU9_08937 2.75e-93 292.0 COG3240@1|root,COG5571@1|root,COG3240@2|Bacteria,COG5571@2|Bacteria,1MWDI@1224|Proteobacteria,1S2RQ@1236|Gammaproteobacteria,1X3QI@135614|Xanthomonadales 135614|Xanthomonadales IN esterase estA - - ko:K12686 - - - - ko00000,ko02000,ko02044 1.B.12.8 - - Autotransporter,Lipase_GDSL k59_1139786_1 1218074.BAXZ01000006_gene1836 5.38e-25 101.0 2AM41@1|root,31BY6@2|Bacteria,1RHP5@1224|Proteobacteria,2VSXQ@28216|Betaproteobacteria,1K2GH@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF3348) - - - - - - - - - - - - DUF3348 k59_1139786_2 477184.KYC_27948 1.05e-12 68.2 COG1196@1|root,COG1196@2|Bacteria,1QVYF@1224|Proteobacteria,2VH31@28216|Betaproteobacteria,3T6G6@506|Alcaligenaceae 28216|Betaproteobacteria D Domain of unknown function (DUF802) - - - - - - - - - - - - DUF802 k59_737522_1 1500893.JQNB01000001_gene2467 3.91e-13 64.3 COG1918@1|root,COG1918@2|Bacteria,1NASN@1224|Proteobacteria,1SFGS@1236|Gammaproteobacteria,1XC9B@135614|Xanthomonadales 135614|Xanthomonadales P FeoA - - - - - - - - - - - - FeoA k59_787665_1 102125.Xen7305DRAFT_00021480 1.16e-61 202.0 2BWJ3@1|root,2Z7IQ@2|Bacteria,1G3WZ@1117|Cyanobacteria 1117|Cyanobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 k59_382181_1 1234364.AMSF01000015_gene3262 4.57e-14 70.1 COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1X39A@135614|Xanthomonadales 135614|Xanthomonadales E Glycine cleavage system regulatory protein gcvR - - ko:K03567 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - ACT_6 k59_382181_2 1163409.UUA_17515 4.28e-39 138.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1X41F@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k59_1437577_1 748247.AZKH_1820 1.11e-109 331.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,2KV73@206389|Rhodocyclales 206389|Rhodocyclales C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k59_737678_1 1346791.M529_03385 4.01e-86 272.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TT4X@28211|Alphaproteobacteria,2K0E1@204457|Sphingomonadales 204457|Sphingomonadales S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 k59_39682_1 436308.Nmar_0279 7.27e-12 63.9 COG0649@1|root,arCOG01548@2157|Archaea,41S62@651137|Thaumarchaeota 651137|Thaumarchaeota C Belongs to the complex I 49 kDa subunit family - - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa k59_39682_2 1229909.NSED_01300 1.87e-94 287.0 COG1005@1|root,arCOG01546@2157|Archaea,41SAT@651137|Thaumarchaeota 651137|Thaumarchaeota C NADH dehydrogenase - - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh k59_1139993_1 330214.NIDE3327 9.62e-06 45.1 COG0724@1|root,COG0724@2|Bacteria 2|Bacteria K RNA recognition motif rbpA - - - - - - - - - - - RRM_1 k59_1139993_2 330214.NIDE0447 4.66e-18 80.1 COG0703@1|root,COG0703@2|Bacteria,3J0R8@40117|Nitrospirae 40117|Nitrospirae F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k59_1091246_1 743720.Psefu_4413 2.34e-112 334.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1YVYG@136845|Pseudomonas putida group 1236|Gammaproteobacteria I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase pycA - 6.3.4.6,6.4.1.1 ko:K01941,ko:K01959 ko00020,ko00220,ko00620,ko00720,ko00791,ko01100,ko01120,ko01200,ko01230,map00020,map00220,map00620,map00720,map00791,map01100,map01120,map01200,map01230 M00173,M00620 R00344,R00774 RC00040,RC00367,RC00378 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k59_1091268_1 944435.AXAJ01000001_gene87 4.99e-37 134.0 COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,2VKYN@28216|Betaproteobacteria,1K37D@119060|Burkholderiaceae 28216|Betaproteobacteria M Gram-negative porin - - - - - - - - - - - - Porin_4 k59_1091304_1 95619.PM1_0201385 4.46e-22 92.4 COG0583@1|root,COG0583@2|Bacteria,1MXRP@1224|Proteobacteria,1RQP1@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator ynfL GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_1,LysR_substrate k59_1091304_2 1439940.BAY1663_00650 1.26e-19 88.2 COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,1RPAT@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily ynfM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08224 - - - - ko00000,ko02000 2.A.1.36 - - MFS_1,Sugar_tr k59_493087_1 1234364.AMSF01000075_gene1947 1.75e-100 297.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,1X51X@135614|Xanthomonadales 135614|Xanthomonadales Q ABC-type transport system involved in resistance to organic solvents permease component yrbE - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE k59_1243888_1 998088.B565_2919 3.95e-98 300.0 2DBBJ@1|root,2Z889@2|Bacteria,1QUGT@1224|Proteobacteria,1RRX9@1236|Gammaproteobacteria,1Y4XE@135624|Aeromonadales 135624|Aeromonadales S Histidine phosphatase superfamily (branch 2) - - - - - - - - - - - - - k59_1539786_1 32042.PstZobell_05633 1.28e-137 413.0 COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1Z1CV@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Belongs to the peptidase S16 family IV02_30220 - - ko:K04770 - - - - ko00000,ko01000,ko01002 - - - AAA_32,Lon_C k59_839601_1 1229909.NSED_00585 1.89e-37 133.0 COG1492@1|root,arCOG00105@2157|Archaea,41SG6@651137|Thaumarchaeota 651137|Thaumarchaeota H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation cobQ - 6.3.5.10 ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05225 RC00010,RC01302 ko00000,ko00001,ko00002,ko01000 - - - CbiA k59_839601_2 1131266.ARWQ01000009_gene955 3.72e-90 276.0 COG0079@1|root,arCOG04273@2157|Archaea,41SGU@651137|Thaumarchaeota 651137|Thaumarchaeota E PFAM Aminotransferase class I and II - - 4.1.1.81 ko:K04720 ko00860,map00860 - R06530 RC00517 ko00000,ko00001,ko01000 - - - Aminotran_1_2 k59_1187812_1 290397.Adeh_2207 7.38e-33 124.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria 1224|Proteobacteria H Methyl-transferase egtB - 1.14.99.50 ko:K18912 ko00340,map00340 - R11013 RC03323,RC03324 ko00000,ko00001,ko01000 - - - DinB_2,FGE-sulfatase k59_1187812_2 42256.RradSPS_2996 1.05e-16 79.0 COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CRDV@84995|Rubrobacteria 84995|Rubrobacteria E Cobalamin-independent synthase, Catalytic domain - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 k59_1039004_1 748247.AZKH_3783 3.02e-50 176.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VNJW@28216|Betaproteobacteria,2KW08@206389|Rhodocyclales 28216|Betaproteobacteria NT Methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,TarH k59_839797_1 1217713.F993_03773 8.79e-50 171.0 COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,1RPNC@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues - - 3.2.1.183 ko:K08068 ko00520,map00520 - - - ko00000,ko00001,ko01000 - - - Epimerase_2 k59_643360_1 1234364.AMSF01000037_gene205 0.000927 42.4 2EUVS@1|root,33NB8@2|Bacteria,1NIKM@1224|Proteobacteria,1SIUP@1236|Gammaproteobacteria,1X7TQ@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - V4R k59_643360_2 1500893.JQNB01000001_gene2285 4.02e-41 149.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1X53V@135614|Xanthomonadales 135614|Xanthomonadales T gtp-binding protein typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k59_438061_1 1049564.TevJSym_an00640 5.28e-19 85.9 COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1J4SK@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth k59_643421_1 666681.M301_1169 4.93e-46 160.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,2KMDA@206350|Nitrosomonadales 206350|Nitrosomonadales E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase k59_643421_2 62928.azo1038 3.87e-31 117.0 COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,2KVMZ@206389|Rhodocyclales 206389|Rhodocyclales O Peptidase M48 - - - - - - - - - - - - Peptidase_M48 k59_89646_1 1229909.NSED_02995 3.89e-108 323.0 COG1914@1|root,arCOG04531@2157|Archaea 2157|Archaea P COG1914 Mn2 and Fe2 transporters of the NRAMP family - - - - - - - - - - - - 5TM-5TMR_LYT,Nramp k59_985592_1 1502851.FG93_06134 9.36e-23 99.0 COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,3JTGR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k59_470465_1 1448139.AI20_20725 1.88e-57 182.0 COG0801@1|root,COG0801@2|Bacteria,1NKUM@1224|Proteobacteria,1SGMD@1236|Gammaproteobacteria 1236|Gammaproteobacteria H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) - - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK k59_768387_1 745411.B3C1_00550 2.1e-65 216.0 COG4776@1|root,COG4776@2|Bacteria,1P563@1224|Proteobacteria,1RP5G@1236|Gammaproteobacteria,1JC3Y@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction rnb GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0008859,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.1.13.1 ko:K01147 - - - - ko00000,ko01000,ko03016 - - - OB_RNB,RNB,S1 k59_668390_1 518766.Rmar_1425 3.03e-30 113.0 COG2259@1|root,COG2259@2|Bacteria,4PK4D@976|Bacteroidetes,1FK9G@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S DoxX - - - - - - - - - - - - DoxX k59_132021_1 666685.R2APBS1_3538 1.58e-94 285.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1X576@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 k59_181793_1 1245471.PCA10_42500 1.76e-66 215.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,1YDNB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP GO:0003333,GO:0003674,GO:0005215,GO:0005283,GO:0005298,GO:0005342,GO:0005343,GO:0005416,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006865,GO:0006869,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0010876,GO:0015075,GO:0015077,GO:0015081,GO:0015171,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015672,GO:0015711,GO:0015718,GO:0015804,GO:0015824,GO:0015849,GO:0015908,GO:0015912,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0033036,GO:0034220,GO:0035725,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039 - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - iSbBS512_1146.SbBS512_E2302 SSF k59_568388_1 1132855.KB913035_gene231 2.06e-30 115.0 COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,2KKJZ@206350|Nitrosomonadales 206350|Nitrosomonadales C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt k59_568388_2 568706.BN118_0361 2.75e-29 116.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,3T1PN@506|Alcaligenaceae 28216|Betaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N k59_1382931_1 287.DR97_3356 5.43e-121 347.0 COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,1S24V@1236|Gammaproteobacteria,1YDT1@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria Q Methionine biosynthesis protein MetW metW - - - - - - - - - - - MetW k59_1382931_2 322710.Avin_03040 9.55e-16 75.9 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine metX GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k59_1269747_1 743720.Psefu_3451 3.51e-61 189.0 COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria,1YYUR@136845|Pseudomonas putida group 1236|Gammaproteobacteria S Domain of unknown function (DUF1820) IV02_29925 - - - - - - - - - - - DUF1820 k59_1269747_2 322710.Avin_09080 9.37e-88 269.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 k59_1419069_1 1120956.JHZK01000007_gene2815 4.56e-43 147.0 COG0625@1|root,COG0625@2|Bacteria,1RA4M@1224|Proteobacteria,2TV0I@28211|Alphaproteobacteria,1JP8D@119043|Rhodobiaceae 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 k59_1419069_2 631454.N177_2475 8.99e-16 78.2 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 k59_1269761_1 1196835.A458_05230 3.3e-104 313.0 COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,1SYCI@1236|Gammaproteobacteria,1YZPZ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria F COG0402 Cytosine deaminase and related metal-dependent hydrolases guaD - 3.5.4.3 ko:K01487 ko00230,ko01100,map00230,map01100 - R01676 RC00204 ko00000,ko00001,ko01000 - - - Amidohydro_1 k59_1068670_1 1458357.BG58_28250 3.75e-92 286.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,1K18V@119060|Burkholderiaceae 28216|Betaproteobacteria P Sulfate transporter antisigma-factor antagonist STAS - - - - - - - - - - - - STAS,Sulfate_transp k59_418242_1 1173264.KI913949_gene498 2.2e-92 284.0 COG3328@1|root,COG3328@2|Bacteria,1G3YG@1117|Cyanobacteria,1HE7N@1150|Oscillatoriales 1117|Cyanobacteria L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut k59_918762_1 1523503.JPMY01000006_gene2187 2.25e-44 147.0 COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Small membrane protein ygdD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF423 k59_418265_1 997884.HMPREF1068_03192 3.76e-13 73.9 COG4695@1|root,COG4695@2|Bacteria,4NW2N@976|Bacteroidetes,2FQR7@200643|Bacteroidia,4AVMP@815|Bacteroidaceae 976|Bacteroidetes S Phage portal protein - - - - - - - - - - - - Phage_portal k59_897051_1 713587.THITH_02720 5.98e-50 169.0 COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria,1WZAN@135613|Chromatiales 135613|Chromatiales L PFAM transposase IS116 IS110 IS902 family - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 k59_297236_1 1205753.A989_01880 5.17e-191 551.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1X555@135614|Xanthomonadales 135614|Xanthomonadales G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB2 - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 k59_1178814_2 477184.KYC_14912 1.42e-44 145.0 COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,2VTZ8@28216|Betaproteobacteria,3T7UX@506|Alcaligenaceae 28216|Betaproteobacteria L Transposase - - - ko:K07497 - - - - ko00000 - - - HTH_Tnp_1 k59_1178814_3 272568.GDI2860 9.26e-29 112.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2JQHW@204441|Rhodospirillales 204441|Rhodospirillales L Integrase core domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve_3 k59_1178836_1 1207063.P24_07334 1.33e-35 129.0 COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2TU33@28211|Alphaproteobacteria,2JQXT@204441|Rhodospirillales 204441|Rhodospirillales H COG2998 ABC-type tungstate transport system, permease component - - - - - - - - - - - - PBP_like_2 k59_1178836_2 631454.N177_1930 1.93e-18 82.8 COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,2TSCU@28211|Alphaproteobacteria,1JQ5M@119043|Rhodobiaceae 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities - - 3.6.3.55 ko:K06857 ko02010,map02010 M00186 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.6.2,3.A.1.6.4 - - ABC_tran k59_1178906_1 1336208.JADY01000004_gene3748 3.74e-39 142.0 COG0583@1|root,COG0583@2|Bacteria,1MXRP@1224|Proteobacteria,2TRVK@28211|Alphaproteobacteria,2JZHV@204441|Rhodospirillales 204441|Rhodospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k59_1079263_1 1296990.H845_1935 3.8e-80 258.0 COG1506@1|root,COG1506@2|Bacteria,1R968@1224|Proteobacteria,2TXT1@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Tannase and feruloyl esterase - - - - - - - - - - - - Tannase k59_679108_1 1094980.Mpsy_2456 6.97e-27 112.0 COG0415@1|root,arCOG02840@2157|Archaea,2XTVM@28890|Euryarchaeota,2NAIC@224756|Methanomicrobia 224756|Methanomicrobia L FAD binding domain of DNA photolyase - - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 k59_1397023_1 1187851.A33M_4045 4.14e-66 214.0 COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2TWTC@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 k59_1233531_1 562970.Btus_2200 5.91e-55 182.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,2783Z@186823|Alicyclobacillaceae 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N k59_1130622_1 1163409.UUA_17737 4.24e-17 80.9 COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria,1RQX0@1236|Gammaproteobacteria 1236|Gammaproteobacteria V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k59_1130622_2 1163409.UUA_17742 5.35e-46 160.0 COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,1X4WM@135614|Xanthomonadales 135614|Xanthomonadales V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k59_976704_1 1500890.JQNL01000001_gene1132 1.83e-17 79.0 COG0251@1|root,COG0251@2|Bacteria,1RD3E@1224|Proteobacteria,1S6NI@1236|Gammaproteobacteria,1X6JQ@135614|Xanthomonadales 135614|Xanthomonadales J translation initiation inhibitor, yjgF family tdcF - - - - - - - - - - - Ribonuc_L-PSP k59_976704_2 1432055.GLUCORHAEAF1_03255 9.5e-34 122.0 COG2010@1|root,COG2010@2|Bacteria,1N8E1@1224|Proteobacteria,2UG6N@28211|Alphaproteobacteria,2JXPG@204441|Rhodospirillales 204441|Rhodospirillales C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 k59_1530765_1 1395571.TMS3_0107250 4.32e-115 341.0 COG0004@1|root,COG0004@2|Bacteria,1MX44@1224|Proteobacteria,1RPVS@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Ammonium transporter - - - - - - - - - - - - Ammonium_transp k59_1329898_1 1229909.NSED_09410 6.03e-32 121.0 COG0520@1|root,arCOG00065@2157|Archaea,41SYH@651137|Thaumarchaeota 651137|Thaumarchaeota E Aminotransferase class-V - - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 k59_1329898_2 436308.Nmar_1762 4.27e-43 141.0 COG1522@1|root,arCOG01117@2157|Archaea,41T58@651137|Thaumarchaeota 651137|Thaumarchaeota K Lrp/AsnC ligand binding domain - - - - - - - - - - - - AsnC_trans_reg k59_482791_1 1122132.AQYH01000004_gene1622 7.7e-37 140.0 COG0492@1|root,COG0492@2|Bacteria,1MVX2@1224|Proteobacteria,2TQN3@28211|Alphaproteobacteria,4B8P5@82115|Rhizobiaceae 28211|Alphaproteobacteria O Cyclic nucleotide-monophosphate binding domain - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_3,cNMP_binding k59_1179105_1 243924.LT42_11360 2.26e-49 163.0 COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,1S2Z2@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q dithiol-disulfide isomerase involved in polyketide biosynthesis - - - - - - - - - - - - DSBA k59_976903_1 1205753.A989_16503 5.4e-93 299.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,1RN1E@1236|Gammaproteobacteria,1X9S0@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k59_1079556_1 1229909.NSED_02335 6.24e-29 108.0 arCOG07871@1|root,arCOG07871@2157|Archaea,41T28@651137|Thaumarchaeota 651137|Thaumarchaeota L COG1061 DNA or RNA helicases of superfamily II - - - - - - - - - - - - - k59_1397475_1 1163409.UUA_07245 3.68e-107 322.0 COG0454@1|root,COG1947@1|root,COG0454@2|Bacteria,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,1X30B@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1,GHMP_kinases_C,GHMP_kinases_N k59_1597512_2 1163409.UUA_09156 1.81e-40 138.0 COG0316@1|root,COG0694@1|root,COG0316@2|Bacteria,COG0694@2|Bacteria,1MU8Y@1224|Proteobacteria,1RN7J@1236|Gammaproteobacteria,1X4F3@135614|Xanthomonadales 135614|Xanthomonadales C Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins nfuA - - ko:K07400 - - - - ko00000 - - - Fe-S_biosyn,NifU k59_529529_1 767434.Fraau_1346 6.18e-112 350.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1X3MZ@135614|Xanthomonadales 135614|Xanthomonadales F Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS k59_977020_2 1121940.AUDZ01000006_gene245 6.33e-18 82.4 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1XIBJ@135619|Oceanospirillales 135619|Oceanospirillales E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - - - - - - - - - - - PALP k59_247586_1 1123237.Salmuc_01769 7.26e-06 50.4 COG0433@1|root,COG0433@2|Bacteria,1QV4K@1224|Proteobacteria,2TVP7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0433 Predicted ATPase - - - ko:K12206 - - - - ko00000,ko02044 3.A.7.9.1 - - - k59_1597593_1 573065.Astex_2474 1.93e-87 275.0 COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,2TUA9@28211|Alphaproteobacteria,2KHMF@204458|Caulobacterales 204458|Caulobacterales M Carboxylesterase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase k59_529609_1 1001585.MDS_2377 2.05e-102 317.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1YDDA@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria O Belongs to the ClpA ClpB family clpA GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N k59_579470_1 767434.Fraau_1161 1.48e-17 81.6 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1RKGT@1224|Proteobacteria,1S6ZQ@1236|Gammaproteobacteria,1X563@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the ompA family mopB - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl,OmpA,TSP_3 k59_247825_1 1234364.AMSF01000088_gene2732 4.99e-21 90.5 COG0834@1|root,COG0834@2|Bacteria,1MWWZ@1224|Proteobacteria,1S2ZV@1236|Gammaproteobacteria,1X47K@135614|Xanthomonadales 135614|Xanthomonadales ET Bacterial periplasmic substrate-binding proteins moxJ - - - - - - - - - - - Ank_2,Ank_4,Ank_5,SBP_bac_3 k59_247825_2 1234364.AMSF01000088_gene2731 8.64e-100 298.0 COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,1SCRY@1236|Gammaproteobacteria,1X8SI@135614|Xanthomonadales 135614|Xanthomonadales C cytochrome - - - - - - - - - - - - Cytochrome_CBB3 k59_830713_2 435908.IDSA_01840 1.63e-18 91.3 COG4796@1|root,COG4796@2|Bacteria,1QVDE@1224|Proteobacteria,1T2C9@1236|Gammaproteobacteria,2QH39@267893|Idiomarinaceae 1236|Gammaproteobacteria U Belongs to the GSP D family - - - - - - - - - - - - Secretin,Secretin_N_2 k59_1179529_1 1101192.KB910516_gene657 1.47e-56 189.0 COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,1JSGY@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Transposase domain (DUF772) - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k59_1597907_1 1458357.BG58_10950 6.69e-38 139.0 2BUGI@1|root,32PSJ@2|Bacteria,1PJCE@1224|Proteobacteria,2W7WE@28216|Betaproteobacteria,1KF9F@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_429258_1 1226994.AMZB01000134_gene4666 2.66e-75 249.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1YDBF@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3318 GDC-P k59_729403_2 745411.B3C1_05060 1.24e-78 240.0 COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,1RQ8Z@1236|Gammaproteobacteria,1J62A@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria FJ COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA miaE - - ko:K06169 - - - - ko00000,ko01000,ko03016 - - - MiaE k59_1531305_1 1163408.UU9_02676 3.93e-51 182.0 COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,1RN9S@1236|Gammaproteobacteria,1X4FQ@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_197943_1 767434.Fraau_2134 1.45e-94 298.0 COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,1RQ2K@1236|Gammaproteobacteria,1X35F@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - ko:K16087 - - - - ko00000,ko02000 1.B.14.2 - - Plug,TonB_dep_Rec k59_483392_1 272560.BPSL2219 2.27e-71 226.0 COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VJVX@28216|Betaproteobacteria,1K2CA@119060|Burkholderiaceae 28216|Betaproteobacteria E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine - - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k59_483392_2 1472716.KBK24_0102710 1.77e-26 108.0 COG0189@1|root,COG0189@2|Bacteria,1NNP5@1224|Proteobacteria,2VIF2@28216|Betaproteobacteria,1K8EA@119060|Burkholderiaceae 28216|Betaproteobacteria HJ ligase activity - - - - - - - - - - - - TPR_19 k59_1280923_1 1163407.UU7_15105 6.23e-95 295.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RWHB@1236|Gammaproteobacteria,1X3VE@135614|Xanthomonadales 135614|Xanthomonadales EU Dipeptidyl aminopeptidase acylaminoacyl peptidase - - - - - - - - - - - - PD40,Peptidase_S9 k59_529961_2 745411.B3C1_15954 3.99e-46 158.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Part of a membrane complex involved in electron transport rnfD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE k59_1280994_1 331869.BAL199_12931 5.43e-95 287.0 COG4177@1|root,COG4177@2|Bacteria,1NPII@1224|Proteobacteria,2TVFT@28211|Alphaproteobacteria,4BRDF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Branched-chain amino acid transport system permease - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k59_977515_1 1218352.B597_005485 5.39e-103 303.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria,1Z3F5@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family hpaG - 4.1.1.68 ko:K05921 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04134,R04380 RC01085,RC02669 ko00000,ko00001,ko00002,ko01000 - - iECO111_1330.ECO111_5214,iEcHS_1320.EcHS_A4584 FAA_hydrolase k59_977515_2 1211579.PP4_18980 5.88e-32 122.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family hpaE - 1.2.1.60 ko:K00151 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04418 RC00254 ko00000,ko00001,ko00002,ko01000 - - iYL1228.KPN_04787 Aldedh k59_248295_1 1163408.UU9_05519 2.96e-61 199.0 COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,1S23W@1236|Gammaproteobacteria,1X4E3@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria rpfE - - - - - - - - - - - - k59_1398247_1 925775.XVE_4880 8.38e-67 228.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X34J@135614|Xanthomonadales 135614|Xanthomonadales V Efflux pump membrane transporter - - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k59_1234526_1 522306.CAP2UW1_4070 9.42e-108 323.0 COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,2VH3S@28216|Betaproteobacteria,1KQZT@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria E Bacterial transglutaminase-like N-terminal region - - - - - - - - - - - - Bact_transglu_N,Transglut_core k59_1429718_2 1136138.JH604622_gene2162 8.25e-50 164.0 2AD2S@1|root,312R0@2|Bacteria,1RDQX@1224|Proteobacteria,1S3Y6@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_298945_1 218140.BPSY_1298 5.13e-25 98.2 COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria,4D18P@85004|Bifidobacteriales 201174|Actinobacteria K Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 k59_633841_1 388413.ALPR1_20148 1.24e-81 267.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47NMF@768503|Cytophagia 976|Bacteroidetes G Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 k59_31764_1 269482.Bcep1808_1600 2.18e-37 136.0 COG2042@1|root,COG3376@2|Bacteria,1MUYH@1224|Proteobacteria,2VJDC@28216|Betaproteobacteria,1K07W@119060|Burkholderiaceae 28216|Betaproteobacteria P Belongs to the NiCoT transporter (TC 2.A.52) family hoxN - - ko:K07241 - - - - ko00000,ko02000 2.A.52.1 - - NicO k59_1030442_1 1452718.JBOY01000030_gene56 5.41e-52 169.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria 1236|Gammaproteobacteria O COG1214 Inactive homolog of metal-dependent proteases yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 k59_1030442_2 95619.PM1_0217085 6.23e-85 255.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - iECH74115_1262.ECH74115_0566,iEKO11_1354.EKO11_3373,iG2583_1286.G2583_0586,iJN746.PP_1506 ADK,ADK_lid k59_729817_1 215803.DB30_5334 3.69e-77 249.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YUKY@29|Myxococcales 28221|Deltaproteobacteria NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N k59_1080457_1 420662.Mpe_A1408 3.61e-11 63.5 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,1KJHB@119065|unclassified Burkholderiales 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB k59_152181_1 470.IX87_19995 2.94e-76 239.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RPDZ@1236|Gammaproteobacteria,3NMM6@468|Moraxellaceae 1236|Gammaproteobacteria E to L-histidinaldehyde and then to L-histidine - - 1.1.1.308 ko:K15509 - - - - ko00000,ko01000 - - - Histidinol_dh k59_1251771_1 504487.JCM19302_879 7.35e-86 279.0 COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia 976|Bacteroidetes M Peptidase M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C k59_901675_1 748247.AZKH_p0018 1.28e-102 305.0 COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VJHD@28216|Betaproteobacteria 28216|Betaproteobacteria E Belongs to the arginase family - - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase k59_1353033_1 1234364.AMSF01000088_gene2709 5.83e-27 108.0 COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,1S1R3@1236|Gammaproteobacteria,1X47H@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF2167) - - - - - - - - - - - - DUF2167 k59_1353033_2 1163409.UUA_11483 6.97e-25 104.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RRAS@1236|Gammaproteobacteria,1X2ZW@135614|Xanthomonadales 135614|Xanthomonadales S HI0933-like protein - - - ko:K07007 - - - - ko00000 - - - HI0933_like k59_401432_1 1163407.UU7_10585 1.51e-52 182.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria,1X50B@135614|Xanthomonadales 135614|Xanthomonadales D Peptidase M23 - - - - - - - - - - - - Peptidase_M23 k59_1502302_1 105559.Nwat_0484 1.06e-06 53.1 COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1WW9X@135613|Chromatiales 135613|Chromatiales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR k59_1502452_1 1001585.MDS_4514 1.29e-11 59.3 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1YGUJ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C 4Fe-4S binding domain fdx1 - - - - - - - - - - - Fer4 k59_1502452_2 322710.Avin_03490 7.59e-91 268.0 COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0053,iSDY_1059.SDY_4064 CTP_transf_like k59_1001933_1 436308.Nmar_1644 3.75e-62 203.0 arCOG08728@1|root,arCOG08728@2157|Archaea,41SW1@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_152623_1 1448139.AI20_10000 1.69e-87 272.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,1Y3HM@135624|Aeromonadales 135624|Aeromonadales J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 k59_152623_2 380703.AHA_1808 0.000996 40.8 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,1Y3JS@135624|Aeromonadales 135624|Aeromonadales F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin k59_152646_1 436308.Nmar_0572 2e-77 243.0 COG1914@1|root,arCOG04531@2157|Archaea 2157|Archaea P COG1914 Mn2 and Fe2 transporters of the NRAMP family - - - - - - - - - - - - 5TM-5TMR_LYT,Nramp k59_351582_1 1415780.JPOG01000001_gene561 1.9e-33 122.0 COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria,1X4G1@135614|Xanthomonadales 135614|Xanthomonadales L COG2826 Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - HTH_38,rve k59_801800_1 396588.Tgr7_0353 1.48e-108 323.0 COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1WWF2@135613|Chromatiales 135613|Chromatiales P Belongs to the sulfate adenylyltransferase family sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 k59_952004_1 572477.Alvin_1906 6.7e-101 305.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1WWPY@135613|Chromatiales 135613|Chromatiales I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k59_1553558_1 1163408.UU9_15337 1.82e-98 305.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,1RMYM@1236|Gammaproteobacteria,1X4XX@135614|Xanthomonadales 135614|Xanthomonadales J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1g,tRNA_bind k59_751835_1 1234364.AMSF01000068_gene2129 7.64e-81 242.0 COG0346@1|root,COG0346@2|Bacteria,1RCAK@1224|Proteobacteria,1SZW8@1236|Gammaproteobacteria,1XC6Z@135614|Xanthomonadales 135614|Xanthomonadales E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase k59_301721_1 290398.Csal_0325 1.21e-32 117.0 COG3384@1|root,COG3384@2|Bacteria,1RA8A@1224|Proteobacteria,1S8CE@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Aromatic-ring-opening dioxygenase LigAB, LigA subunit ligA_1 - 1.13.11.8 ko:K04100 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigA k59_952097_1 436308.Nmar_0642 3.27e-91 279.0 COG0389@1|root,arCOG04582@2157|Archaea,41SDV@651137|Thaumarchaeota 651137|Thaumarchaeota L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis dbh - 2.7.7.7 ko:K04479 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k59_853283_1 1144342.PMI40_04277 1.6e-14 72.0 COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,2VH0I@28216|Betaproteobacteria,476X1@75682|Oxalobacteraceae 28216|Betaproteobacteria G Permease component of ABC-type sugar transporter ugpA - - ko:K05814 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - BPD_transp_1 k59_853283_2 1097668.BYI23_A024000 1.52e-40 147.0 COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,2VH0F@28216|Betaproteobacteria,1K36P@119060|Burkholderiaceae 28216|Betaproteobacteria G PFAM extracellular solute-binding protein family 1 ugpB - - ko:K05813 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - SBP_bac_8 k59_1202234_1 1453503.AU05_09265 9.22e-12 63.2 COG2259@1|root,COG2259@2|Bacteria,1R23F@1224|Proteobacteria,1T5G1@1236|Gammaproteobacteria,1YM0E@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Methylamine utilisation protein MauE - - - - - - - - - - - - MauE k59_1202234_2 95619.PM1_0224660 3.86e-77 241.0 COG3391@1|root,COG3391@2|Bacteria,1R8X0@1224|Proteobacteria,1S1R2@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Methylamine dehydrogenase heavy chain (MADH) - - 1.4.9.1 ko:K15229 ko00680,ko01120,map00680,map01120 - R00606 RC00189 ko00000,ko00001,ko01000 - - - Me-amine-dh_H k59_253169_1 1380394.JADL01000004_gene5775 2.18e-71 229.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TSJQ@28211|Alphaproteobacteria,2JPM5@204441|Rhodospirillales 204441|Rhodospirillales E Belongs to the binding-protein-dependent transport system permease family livM - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2,DUF3382 k59_253169_2 1437448.AZRT01000002_gene2265 5.46e-09 56.6 COG0411@1|root,COG3743@1|root,COG0411@2|Bacteria,COG3743@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria,1J1DE@118882|Brucellaceae 28211|Alphaproteobacteria E AAA domain braF GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 3.5.4.44 ko:K01995,ko:K15783 ko00260,ko01100,ko02010,ko02024,map00260,map01100,map02010,map02024 M00237 R09800 RC02661 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k59_501791_1 745411.B3C1_14360 5.5e-111 327.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,1RPX5@1236|Gammaproteobacteria,1JBV4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C oxidoreductases (related to aryl-alcohol dehydrogenases) yccK - - - - - - - - - - - Aldo_ket_red k59_153158_1 1234364.AMSF01000033_gene415 1.11e-93 295.0 COG3408@1|root,COG3408@2|Bacteria,1QWGV@1224|Proteobacteria,1RYXV@1236|Gammaproteobacteria,1X56X@135614|Xanthomonadales 135614|Xanthomonadales G Glycogen debranching enzyme - - - - - - - - - - - - Bac_rhamnosid6H,GDE_C k59_551897_1 454957.IA64_16305 8.6e-144 418.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1X3DG@135614|Xanthomonadales 135614|Xanthomonadales C Belongs to the aldehyde dehydrogenase family aldA - - ko:K00138 ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120 - R00711 RC00047 ko00000,ko00001,ko01000 - - - Aldedh k59_752036_1 95619.PM1_0203270 2.33e-85 270.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k59_1302327_1 477228.YO5_18035 2.3e-64 209.0 COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,1RQ37@1236|Gammaproteobacteria,1Z2GM@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E COG0527 Aspartokinases lysC GO:0003674,GO:0003824,GO:0004072,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7 k59_1302327_2 497321.C664_13604 3.38e-13 68.9 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria 1224|Proteobacteria P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) MA20_07375 - - - - - - - - - - - Na_H_Exchanger,TrkA_N k59_351937_1 1178482.BJB45_01105 3.47e-11 62.0 2E35S@1|root,32Y5P@2|Bacteria,1N6WS@1224|Proteobacteria,1SD5T@1236|Gammaproteobacteria,1XMKJ@135619|Oceanospirillales 135619|Oceanospirillales S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 k59_351937_2 1280948.HY36_17665 3.36e-12 64.3 COG0454@1|root,COG0456@2|Bacteria,1RA6D@1224|Proteobacteria,2UC27@28211|Alphaproteobacteria 28211|Alphaproteobacteria K COG0456 Acetyltransferases - - - - - - - - - - - - Acetyltransf_1 k59_1452933_1 379731.PST_2843 4.36e-77 237.0 COG3258@1|root,COG3258@2|Bacteria,1NIQK@1224|Proteobacteria,1RZH1@1236|Gammaproteobacteria,1Z07S@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria C COG3258 Cytochrome c - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016669,GO:0050338,GO:0055114 1.8.2.2 ko:K19713 - - - - ko00000,ko01000 - - - Cytochrom_C,Cytochrome_CBB3 k59_2337_1 743720.Psefu_1535 5.5e-89 263.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S82S@1236|Gammaproteobacteria,1YWFU@136845|Pseudomonas putida group 1236|Gammaproteobacteria M Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA k59_2352_1 436308.Nmar_1416 7.64e-31 114.0 COG0020@1|root,arCOG01532@2157|Archaea,41S8J@651137|Thaumarchaeota 651137|Thaumarchaeota H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids uppS - 2.5.1.89 ko:K15888 ko00900,map00900 - R09730 RC00279,RC02839 ko00000,ko00001,ko01000 - - - Prenyltransf k59_2352_2 436308.Nmar_1417 2.87e-73 222.0 COG0494@1|root,arCOG01078@2157|Archaea,41SPS@651137|Thaumarchaeota 651137|Thaumarchaeota L NUDIX domain - - - - - - - - - - - - NUDIX k59_1554323_2 1177179.A11A3_00700 1.02e-42 149.0 COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria,1XJAX@135619|Oceanospirillales 135619|Oceanospirillales L Integrase catalytic - - - - - - - - - - - - HTH_38,rve k59_2387_1 745411.B3C1_16219 1.63e-122 359.0 COG4225@1|root,COG4225@2|Bacteria,1MU2J@1224|Proteobacteria,1RR65@1236|Gammaproteobacteria,1J5PP@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - - - - - - - - - - DUF4861,Glyco_hydro_88 k59_1002398_1 745411.B3C1_16466 5.81e-110 335.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,1J517@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB k59_302170_1 1229909.NSED_01900 1.09e-49 162.0 COG0605@1|root,arCOG04147@2157|Archaea,41S6C@651137|Thaumarchaeota 651137|Thaumarchaeota P Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N k59_302170_2 436308.Nmar_0395 2e-28 106.0 COG1730@1|root,arCOG01341@2157|Archaea,41SSP@651137|Thaumarchaeota 651137|Thaumarchaeota O Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding pfdA - - ko:K04797 - - - - ko00000,ko03110 - - - Prefoldin k59_752245_1 666685.R2APBS1_3274 9.71e-108 329.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1X3X2@135614|Xanthomonadales 135614|Xanthomonadales M Catalyzes cross-linking of the peptidoglycan cell wall at the division septum ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase k59_952537_1 322710.Avin_34840 1.13e-95 295.0 COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,1RPVC@1236|Gammaproteobacteria 1236|Gammaproteobacteria V (ABC) transporter ygaD - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran k59_652151_1 322710.Avin_41670 1.24e-125 362.0 COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,1RMM9@1236|Gammaproteobacteria 1236|Gammaproteobacteria CO May be involved in the transport of PQQ or its precursor to the periplasm pqqB GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - ko:K06136 - - - - ko00000 - - - Lactamase_B_2 k59_1002498_1 1515746.HR45_04775 1.19e-21 94.7 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_6,Hydrolase_4 k59_1002498_2 1041139.KB902690_gene682 8.73e-06 47.4 COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,2TT1M@28211|Alphaproteobacteria,4B9IZ@82115|Rhizobiaceae 28211|Alphaproteobacteria P CorA-like Mg2+ transporter protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA k59_2562_1 745411.B3C1_07064 2.44e-109 326.0 COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,1RM9W@1236|Gammaproteobacteria,1J55H@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab k59_2581_1 1234364.AMSF01000088_gene2711 3.53e-134 409.0 COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1X372@135614|Xanthomonadales 135614|Xanthomonadales NU General secretion pathway protein xpsD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N k59_1152730_1 1121396.KB892913_gene116 5.7e-98 305.0 COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,42WI2@68525|delta/epsilon subdivisions,2WRPD@28221|Deltaproteobacteria,2MQ18@213118|Desulfobacterales 28221|Deltaproteobacteria S Transposase zinc-binding domain - - - - - - - - - - - - Y2_Tnp,Zn_Tnp_IS91 k59_1554683_1 1163408.UU9_10774 1.63e-37 136.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1X3AN@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt k59_602443_1 1294143.H681_16050 8.34e-09 55.5 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria 1236|Gammaproteobacteria I malonyl CoA-acyl carrier protein transacylase fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598 Acyl_transf_1 k59_602443_2 216595.PFLU_4707 3.94e-62 200.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1YNN7@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - iEcDH1_1363.EcDH1_2557,iSFxv_1172.SFxv_1246,iY75_1357.Y75_RS05695 FA_synthesis k59_2596_1 1234364.AMSF01000013_gene688 1.53e-15 75.9 COG5006@1|root,COG5006@2|Bacteria,1MXR7@1224|Proteobacteria,1RPFH@1236|Gammaproteobacteria,1X641@135614|Xanthomonadales 135614|Xanthomonadales S EamA-like transporter family - - - ko:K11939 - - - - ko00000,ko02000 2.A.7.3.6 - - EamA k59_153848_1 436308.Nmar_0109 1.94e-110 327.0 COG1537@1|root,arCOG01741@2157|Archaea,41S6V@651137|Thaumarchaeota 651137|Thaumarchaeota J May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity pelA - - ko:K06965 ko03015,map03015 - - - ko00000,ko00001 - - - eRF1_1,eRF1_3 k59_1354589_2 1163409.UUA_15983 0.000228 43.1 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1X3PI@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer k59_352251_1 95619.PM1_0228995 2.32e-34 127.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_352251_2 1499686.BN1079_02586 8.34e-17 79.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,1RN5P@1236|Gammaproteobacteria 1236|Gammaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N k59_254061_1 666685.R2APBS1_3027 1.68e-29 108.0 2A4K2@1|root,30T6P@2|Bacteria,1PCV9@1224|Proteobacteria,1SY07@1236|Gammaproteobacteria,1X735@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_254061_2 1234364.AMSF01000033_gene362 1.16e-49 158.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1X7EK@135614|Xanthomonadales 135614|Xanthomonadales C ferredoxin - - - - - - - - - - - - Fer4,Fer4_7 k59_952696_1 745411.B3C1_12699 2.64e-98 298.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1J4XQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N k59_1453363_1 477228.YO5_13588 1.11e-67 207.0 COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,1S61S@1236|Gammaproteobacteria,1Z2VJ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria K transcriptional - - - - - - - - - - - - MerR_1 k59_352353_1 666685.R2APBS1_1414 3.99e-38 130.0 COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1SYIJ@1236|Gammaproteobacteria,1X7E5@135614|Xanthomonadales 135614|Xanthomonadales K helix_turn_helix, mercury resistance - - - ko:K19591 - M00769 - - ko00000,ko00002,ko01504,ko03000 - - - MerR,MerR-DNA-bind,MerR_1 k59_652375_1 414684.RC1_3457 1.05e-34 123.0 2B1QU@1|root,31U6H@2|Bacteria,1N3JH@1224|Proteobacteria,2UG75@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3224) - - - - - - - - - - - - DUF3224 k59_652375_2 1219375.CM002139_gene2897 1.4e-13 70.9 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1X55K@135614|Xanthomonadales 135614|Xanthomonadales CH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - - - - - - - - - - FAD_binding_3 k59_1202979_1 686578.AFFX01000001_gene1696 2.23e-85 259.0 COG0583@1|root,COG0583@2|Bacteria,1MXR5@1224|Proteobacteria,1SYUU@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k59_552456_1 1125973.JNLC01000011_gene585 9.66e-73 230.0 COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TT8C@28211|Alphaproteobacteria,3JXM0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase k59_204333_1 1234364.AMSF01000068_gene2149 1.5e-143 430.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,1X3DK@135614|Xanthomonadales 135614|Xanthomonadales J due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 k59_1002812_1 1229909.NSED_04760 5.62e-48 162.0 COG1378@1|root,arCOG02037@2157|Archaea,41T5N@651137|Thaumarchaeota 651137|Thaumarchaeota K transcriptional - - - - - - - - - - - - TrmB k59_204340_1 1121937.AUHJ01000009_gene1566 9.42e-58 182.0 COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,468KZ@72275|Alteromonadaceae 1236|Gammaproteobacteria M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL k59_204348_1 1500890.JQNL01000001_gene1970 3.43e-82 256.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1X348@135614|Xanthomonadales 135614|Xanthomonadales HJ Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - - - - - - - - - - Dala_Dala_lig_C,RLAN,RimK k59_1203037_1 1333998.M2A_0558 1.22e-83 263.0 COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,2U1B0@28211|Alphaproteobacteria,4BPJI@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria CP Proton-conducting membrane transporter nuoL2 - 1.6.5.3 ko:K00341,ko:K05568 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Proton_antipo_M,Proton_antipo_N k59_352481_1 903818.KI912268_gene651 1.41e-07 52.8 COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria 57723|Acidobacteria T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg k59_352481_2 236814.IX39_12800 7.6e-09 59.7 COG4585@1|root,COG4585@2|Bacteria,4NNE1@976|Bacteroidetes,1I1SW@117743|Flavobacteriia,3ZQV9@59732|Chryseobacterium 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 k59_154366_1 395019.Bmul_3078 2.83e-104 313.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,1K2M9@119060|Burkholderiaceae 28216|Betaproteobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N k59_902756_1 1500890.JQNL01000001_gene1606 4.65e-75 239.0 COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,1X3FX@135614|Xanthomonadales 135614|Xanthomonadales I Long-chain fatty acid transport protein fadL - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X k59_3019_1 1234364.AMSF01000007_gene471 6.25e-42 149.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,1X322@135614|Xanthomonadales 135614|Xanthomonadales N Flagellar motor protein motB1 - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA k59_1102940_1 1454004.AW11_01300 8.16e-104 308.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria 28216|Betaproteobacteria C PFAM Thiamine pyrophosphate - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C k59_1403560_1 745411.B3C1_15367 6.74e-61 199.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat k59_1403560_2 745411.B3C1_15362 5.98e-57 189.0 COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria,1RQX0@1236|Gammaproteobacteria 1236|Gammaproteobacteria V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD k59_652527_1 1234364.AMSF01000025_gene3695 9.45e-101 319.0 COG1629@1|root,COG4771@2|Bacteria,1PSM0@1224|Proteobacteria,1T0NW@1236|Gammaproteobacteria,1X3X1@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k59_452737_1 479434.Sthe_1231 1.74e-46 158.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 k59_42373_2 521719.ATXQ01000008_gene1044 9.03e-85 259.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1YD6N@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E DegT/DnrJ/EryC1/StrS aminotransferase family alaA GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 k59_1342280_1 85643.Tmz1t_1298 2.53e-93 279.0 COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,2VJ19@28216|Betaproteobacteria,2KV78@206389|Rhodocyclales 206389|Rhodocyclales G to the hyi family hfi - 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 - R01394 RC00511 ko00000,ko00001,ko01000 - - - AP_endonuc_2 k59_91986_1 743720.Psefu_2248 3.59e-79 246.0 COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1YXKC@136845|Pseudomonas putida group 1236|Gammaproteobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX k59_740677_1 1229909.NSED_05600 2.81e-82 251.0 COG0668@1|root,arCOG01568@2157|Archaea,41T3B@651137|Thaumarchaeota 651137|Thaumarchaeota M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel k59_1493131_1 1523503.JPMY01000037_gene1748 1.08e-67 231.0 COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG0643 Chemotaxis protein histidine kinase and related kinases chpA - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg k59_842487_1 1001585.MDS_3572 4.55e-09 57.4 COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,1YD2C@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T His Kinase A (phosphoacceptor) domain qseC - 2.7.13.3 ko:K02484,ko:K07645 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 2CSK_N,HATPase_c,HisKA k59_842487_2 1182590.BN5_00343 2.08e-44 147.0 COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1S01K@1236|Gammaproteobacteria,1YH30@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Transposase domain (DUF772) - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 k59_740876_1 264732.Moth_2293 5.25e-09 62.4 COG2309@1|root,COG2309@2|Bacteria,1UMYG@1239|Firmicutes,24BYI@186801|Clostridia,42GN7@68295|Thermoanaerobacterales 186801|Clostridia E Thermophilic metalloprotease (M29) - - - - - - - - - - - - Peptidase_M29 k59_646747_1 395493.BegalDRAFT_0086 1.57e-82 273.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,460BV@72273|Thiotrichales 72273|Thiotrichales E Bacterial NAD-glutamate dehydrogenase - - 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH k59_1493402_1 1122614.JHZF01000016_gene423 1.07e-06 50.1 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQNH@28211|Alphaproteobacteria,2PF36@252301|Oceanicola 28211|Alphaproteobacteria P Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY k59_1493402_2 237609.PSAKL28_24020 4.04e-77 236.0 COG1173@1|root,COG1173@2|Bacteria,1MU0P@1224|Proteobacteria,1RVZU@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N k59_842631_1 436308.Nmar_0417 1.56e-17 76.3 arCOG10524@1|root,arCOG10524@2157|Archaea,41SVP@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_842631_2 436308.Nmar_0418 1.69e-115 332.0 arCOG04033@1|root,arCOG04033@2157|Archaea,41SM5@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_591681_1 1163408.UU9_14695 5.15e-13 68.2 COG2433@1|root,COG2433@2|Bacteria,1N0ZS@1224|Proteobacteria,1SX1C@1236|Gammaproteobacteria,1X702@135614|Xanthomonadales 135614|Xanthomonadales S Pfam Transposase IS66 - - - - - - - - - - - - DUF4124 k59_591681_2 1234364.AMSF01000025_gene3544 1.3e-113 348.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1X4Z1@135614|Xanthomonadales 135614|Xanthomonadales G phosphomannomutase - - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV k59_497027_1 666685.R2APBS1_1587 8.15e-33 126.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria,1X35C@135614|Xanthomonadales 135614|Xanthomonadales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P k59_1143456_1 1234364.AMSF01000024_gene3831 4e-22 94.7 COG3739@1|root,COG3739@2|Bacteria,1PMEC@1224|Proteobacteria,1S0M3@1236|Gammaproteobacteria,1XACA@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF817) - - - - - - - - - - - - DUF817 k59_647017_1 1163407.UU7_02632 3.21e-35 135.0 COG2382@1|root,COG2382@2|Bacteria,1R6XH@1224|Proteobacteria,1SPDA@1236|Gammaproteobacteria,1X4S9@135614|Xanthomonadales 135614|Xanthomonadales P Enterochelin esterase - - - - - - - - - - - - Esterase k59_941441_2 518766.Rmar_0529 5.62e-36 137.0 COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - 1.17.1.4,1.2.5.3 ko:K03520,ko:K11177 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103,R11168 RC00143,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 k59_50043_2 436308.Nmar_0864 7.86e-43 147.0 arCOG06534@1|root,arCOG06534@2157|Archaea 2157|Archaea S acid phosphatase activity - - - - - - - - - - - - He_PIG k59_500307_1 1234364.AMSF01000075_gene1906 1.09e-27 105.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,1RMFG@1236|Gammaproteobacteria,1X343@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 k59_500307_2 666685.R2APBS1_3316 2.31e-66 218.0 COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1X4FF@135614|Xanthomonadales 135614|Xanthomonadales P Potassium transporter TrkA sac1 - - - - - - - - - - - CitMHS,TrkA_C k59_1100683_1 1234364.AMSF01000053_gene1274 3.48e-37 125.0 COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,1SC8Q@1236|Gammaproteobacteria,1X88Q@135614|Xanthomonadales 135614|Xanthomonadales C rubredoxin rubA - - - - - - - - - - - Rubredoxin k59_1100683_2 1118235.CAJH01000022_gene1380 5.6e-44 151.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,1X6BT@135614|Xanthomonadales 135614|Xanthomonadales H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI k59_100258_1 1276920.ADIAG_02194 6.91e-29 120.0 COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,1W7TQ@1268|Micrococcaceae 201174|Actinobacteria C Pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 k59_850692_1 330214.NIDE0836 3.45e-102 316.0 COG1048@1|root,COG1048@2|Bacteria,3J0E6@40117|Nitrospirae 40117|Nitrospirae C Aconitase C-terminal domain - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C k59_1300867_1 666685.R2APBS1_0556 6.68e-10 60.8 COG3637@1|root,COG3637@2|Bacteria,1QFTJ@1224|Proteobacteria,1TD3U@1236|Gammaproteobacteria,1XA2I@135614|Xanthomonadales 135614|Xanthomonadales M OmpA-like transmembrane domain - - - - - - - - - - - - OMP_b-brl k59_850726_1 32042.PstZobell_15744 9.98e-51 174.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,1RPC3@1236|Gammaproteobacteria,1Z0HK@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - iJN746.PP_0104 COX1 k59_850726_2 1215114.BBIU01000003_gene348 9.82e-58 189.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,1RP4H@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrome_CBB3 k59_650524_1 157783.LK03_01135 2.23e-42 144.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,1S8G8@1236|Gammaproteobacteria 1236|Gammaproteobacteria L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes nudL - - - - - - - - - - - NUDIX k59_100381_2 744980.TRICHSKD4_3108 1.66e-37 136.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TT26@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family livM - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k59_1551229_1 1118153.MOY_01257 1.53e-90 275.0 COG2113@1|root,COG2113@2|Bacteria,1MVIG@1224|Proteobacteria,1RRNK@1236|Gammaproteobacteria,1XH6G@135619|Oceanospirillales 135619|Oceanospirillales E Glycine betaine - - - ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC k59_600582_1 1126627.BAWE01000002_gene873 6.38e-13 74.7 COG0784@1|root,COG4191@1|root,COG5000@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,3JTQS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1 k59_300408_1 436308.Nmar_1250 7.22e-36 133.0 COG3794@1|root,arCOG02926@2157|Archaea 2157|Archaea C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - Copper-bind,Kazal_1 k59_200607_1 1218075.BAYA01000029_gene5824 3.72e-58 202.0 COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,2VMHM@28216|Betaproteobacteria,1KG9S@119060|Burkholderiaceae 28216|Betaproteobacteria T GAF domain - - - - - - - - - - - - GAF,GGDEF,PAS,PAS_4,PAS_9 k59_800731_1 1452718.JBOY01000006_gene2803 2.25e-109 328.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria 1236|Gammaproteobacteria T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains cbrB - - - - - - - - - - - Response_reg,Sigma54_activat k59_374_1 1163408.UU9_08555 1.19e-48 165.0 COG0790@1|root,COG0790@2|Bacteria,1R909@1224|Proteobacteria,1T86F@1236|Gammaproteobacteria,1X7U4@135614|Xanthomonadales 135614|Xanthomonadales S COG0790 FOG TPR repeat, SEL1 subfamily - - - - - - - - - - - - Sel1 k59_350525_1 743720.Psefu_0377 5.07e-37 127.0 2EQ2V@1|root,33HP8@2|Bacteria,1NI2K@1224|Proteobacteria,1SHMN@1236|Gammaproteobacteria,1YZ0B@136845|Pseudomonas putida group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_750749_1 1316936.K678_09550 2.77e-37 133.0 COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,2TSP3@28211|Alphaproteobacteria,2JRSB@204441|Rhodospirillales 204441|Rhodospirillales M effector of murein hydrolase - - - - - - - - - - - - LrgB k59_750749_2 745411.B3C1_13239 1e-21 92.8 COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,1RMWR@1236|Gammaproteobacteria,1J9QA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhA GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006067,GO:0006082,GO:0006083,GO:0006089,GO:0006090,GO:0006091,GO:0006103,GO:0006105,GO:0006113,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008720,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015942,GO:0015980,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019318,GO:0019362,GO:0019637,GO:0019660,GO:0019664,GO:0019666,GO:0019693,GO:0019752,GO:0032787,GO:0034308,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0050896,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0070404,GO:0071704,GO:0072521,GO:0072524,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901615 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - iJN746.PP_1649,iPC815.YPO2329,iSFV_1184.SFV_1805,iSF_1195.SF1814,iSFxv_1172.SFxv_2031,iS_1188.S1459 2-Hacid_dh,2-Hacid_dh_C k59_650696_1 1265756.AWZW01000008_gene1282 3.58e-105 322.0 COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,2TSN4@28211|Alphaproteobacteria 28211|Alphaproteobacteria C succinate dehydrogenase fumarate reductase, flavoprotein subunit MA20_14860 - 1.8.99.2 ko:K00394 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C k59_950932_2 436308.Nmar_1406 1.21e-24 97.4 COG0071@1|root,arCOG01833@2157|Archaea 2157|Archaea O Belongs to the small heat shock protein (HSP20) family - - - - - - - - - - - - - k59_250827_1 1109445.AGSX01000033_gene3195 1.66e-99 294.0 COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,1RYDR@1236|Gammaproteobacteria,1Z1W8@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component braF-2 - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C k59_1351466_1 1380355.JNIJ01000022_gene3589 5.52e-102 302.0 COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TRG7@28211|Alphaproteobacteria,3JS2V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S beta-keto acid cleavage enzyme - - 2.3.1.247 ko:K18013 ko00310,map00310 - R10564 RC02728,RC03199 ko00000,ko00001,ko01000 - - - BKACE k59_250880_1 745411.B3C1_15472 1.75e-114 337.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1J4YZ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 iE2348C_1286.E2348C_0187,iEcolC_1368.EcolC_3478 LpxB k59_800863_1 1408419.JHYG01000006_gene2738 9.84e-36 139.0 COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2TU5Q@28211|Alphaproteobacteria,2JWTS@204441|Rhodospirillales 204441|Rhodospirillales M Carbohydrate-selective porin, OprB family - - - ko:K07267 - - - - ko00000,ko02000 1.B.19.1 - - OprB k59_1501363_1 399739.Pmen_3436 1.72e-110 332.0 COG1292@1|root,COG1292@2|Bacteria,1MV0K@1224|Proteobacteria,1RP3E@1236|Gammaproteobacteria,1YFC8@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria M BCCT, betaine/carnitine/choline family transporter - - - ko:K02168 - - - - ko00000,ko02000 2.A.15.1.3,2.A.15.1.4 - - BCCT k59_1051113_1 1500890.JQNL01000001_gene1778 3.94e-36 127.0 COG0515@1|root,COG0515@2|Bacteria,1PKI9@1224|Proteobacteria,1TKGM@1236|Gammaproteobacteria,1XAHS@135614|Xanthomonadales 135614|Xanthomonadales KLT PhoP regulatory network protein YrbL - - - - - - - - - - - - YrbL-PhoP_reg k59_1051124_2 1541883.A0A088FRT0_9CAUD 9.71e-212 616.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QJPJ@10662|Myoviridae 10662|Myoviridae S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0019012 - - - - - - - - - - - k59_1051124_3 794903.OPIT5_03855 5.27e-79 263.0 COG5511@1|root,COG5511@2|Bacteria 2|Bacteria F Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 k59_851438_1 399739.Pmen_3270 2.53e-27 107.0 COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,1YJ36@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Carbon-nitrogen hydrolase nthA - - - - - - - - - - - CN_hydrolase k59_851438_2 1218076.BAYB01000007_gene1347 5.17e-63 197.0 COG0824@1|root,COG0824@2|Bacteria,1RF7Q@1224|Proteobacteria,2VR5T@28216|Betaproteobacteria,1K3R1@119060|Burkholderiaceae 28216|Betaproteobacteria S Thioesterase-like superfamily fcbC2 - 3.1.2.23 ko:K01075 ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120 - R01301 RC00004,RC00174 ko00000,ko00001,ko01000 - - - 4HBT_2 k59_750934_1 322710.Avin_06520 3.77e-127 388.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria 1236|Gammaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k59_300775_1 1005395.CSV86_13265 9.33e-72 231.0 COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,1T1IK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Arylsulfotransferase (ASST) - - - - - - - - - - - - Arylsulfotran_2,Arylsulfotrans k59_1051164_1 671143.DAMO_2755 9.19e-41 152.0 COG0568@1|root,COG0568@2|Bacteria,2NNY9@2323|unclassified Bacteria 2|Bacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_951137_1 641107.CDLVIII_3430 2.66e-18 89.4 COG5433@1|root,COG5433@2|Bacteria,1TRZS@1239|Firmicutes,25DWK@186801|Clostridia,36UFN@31979|Clostridiaceae 186801|Clostridia L DDE_Tnp_1-associated - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_assoc k59_151114_2 640510.BC1001_1781 3.65e-78 271.0 COG4643@1|root,COG4643@2|Bacteria,1R5M0@1224|Proteobacteria,2VPIH@28216|Betaproteobacteria,1KFHF@119060|Burkholderiaceae 28216|Betaproteobacteria L Protein of unknown function (DUF3631) - - - ko:K06919 - - - - ko00000 - - - DUF3631,Toprim_3,Toprim_4 k59_751012_1 296591.Bpro_2800 8.14e-101 308.0 COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2VHRD@28216|Betaproteobacteria,4ABWV@80864|Comamonadaceae 28216|Betaproteobacteria EH Belongs to the TPP enzyme family oxc - 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 - R01908 RC00620 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k59_851759_1 1408254.T458_07330 3.22e-84 264.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,26QNQ@186822|Paenibacillaceae 91061|Bacilli E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 k59_901229_1 767434.Fraau_2914 1.92e-13 70.5 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1X42C@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase k59_901229_2 1500890.JQNL01000001_gene2990 3.6e-49 163.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1RPF6@1236|Gammaproteobacteria,1X6GJ@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI k59_1401653_1 694060.D2K0B2_9CAUD 5.02e-37 135.0 4QATB@10239|Viruses,4QVUZ@35237|dsDNA viruses no RNA stage,4QPGA@28883|Caudovirales,4QI8J@10662|Myoviridae 10662|Myoviridae S metabolic process - - - - - - - - - - - - - k59_1401653_3 349102.Rsph17025_1730 3.86e-17 80.9 2DPEC@1|root,331RJ@2|Bacteria,1N7D6@1224|Proteobacteria,2UFU5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - k59_1401653_5 272630.MexAM1_META1p3981 3.19e-33 120.0 COG1694@1|root,COG1694@2|Bacteria,1N3XF@1224|Proteobacteria,2UG4F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Mazg nucleotide pyrophosphohydrolase - - - - - - - - - - - - - k59_851901_1 1500893.JQNB01000001_gene1262 7.07e-74 231.0 COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,1RN9D@1236|Gammaproteobacteria,1X3ZT@135614|Xanthomonadales 135614|Xanthomonadales C Heme copper-type cytochrome quinol oxidase subunit 3 cox3 - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 k59_651087_1 1121127.JAFA01000062_gene3680 3.74e-114 332.0 COG1028@1|root,COG1028@2|Bacteria,1MXNY@1224|Proteobacteria,2VN50@28216|Betaproteobacteria,1K3D6@119060|Burkholderiaceae 28216|Betaproteobacteria IQ Short-chain dehydrogenase reductase sdr - - - - - - - - - - - - adh_short_C2 k59_1552405_1 1207076.ALAT01000047_gene3489 7.21e-97 294.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1Z0WS@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - ko:K21393 - - - - ko00000,ko02000 2.A.56.1 - - DctM k59_50816_1 323848.Nmul_A2344 8.83e-88 274.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,372Q8@32003|Nitrosomonadales 28216|Betaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 k59_601235_1 1234364.AMSF01000024_gene3832 3.72e-106 317.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1X3XK@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT k59_1201650_1 1163408.UU9_03213 6.76e-16 77.4 COG3637@1|root,COG3637@2|Bacteria,1PG15@1224|Proteobacteria,1SX94@1236|Gammaproteobacteria,1X5YW@135614|Xanthomonadales 135614|Xanthomonadales M OmpA-like transmembrane domain - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OMP_b-brl k59_1101563_1 1121920.AUAU01000004_gene919 4.52e-23 97.1 COG0517@1|root,COG0517@2|Bacteria 2|Bacteria S IMP dehydrogenase activity acuB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - ko:K04767 - - - - ko00000 - - - ACT,CBS k59_101855_1 1234364.AMSF01000075_gene1965 1.41e-52 168.0 COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,1X773@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the UPF0149 family - - - ko:K09895 - - - - ko00000 - - - UPF0149 k59_101855_2 1163407.UU7_08323 1.17e-123 364.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1X34E@135614|Xanthomonadales 135614|Xanthomonadales E aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k59_1101575_1 1234364.AMSF01000072_gene1814 4.95e-48 163.0 COG0596@1|root,COG0596@2|Bacteria,1QVQ5@1224|Proteobacteria,1S5PD@1236|Gammaproteobacteria,1X5RP@135614|Xanthomonadales 135614|Xanthomonadales S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1 k59_118223_1 983917.RGE_24430 1.04e-61 202.0 COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2VIE7@28216|Betaproteobacteria,1KJUY@119065|unclassified Burkholderiales 28216|Betaproteobacteria S N-terminal domain of oxidoreductase - - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N k59_960657_1 1123393.KB891316_gene1919 2.2e-22 98.6 COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,1KS2S@119069|Hydrogenophilales 119069|Hydrogenophilales CO Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps - - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 k59_960657_2 1121035.AUCH01000006_gene646 1.52e-27 103.0 COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,2KX0I@206389|Rhodocyclales 206389|Rhodocyclales P protein involved in tolerance to divalent cations cutA1 - - ko:K03926 - - - - ko00000 - - - CutA1 k59_1511554_1 202952.BBLI01000001_gene116 5.44e-45 162.0 COG3182@1|root,COG3182@2|Bacteria,1MVET@1224|Proteobacteria,1RNR9@1236|Gammaproteobacteria,3NJWJ@468|Moraxellaceae 1236|Gammaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM k59_560065_1 1131266.ARWQ01000006_gene258 9.06e-41 140.0 COG1628@1|root,arCOG00928@2157|Archaea,41SMQ@651137|Thaumarchaeota 651137|Thaumarchaeota L Protein of unknown function DUF99 - - - ko:K09120 - - - - ko00000 - - - DUF99 k59_560065_2 436308.Nmar_0632 2.74e-28 103.0 arCOG08753@1|root,arCOG08753@2157|Archaea,41T9W@651137|Thaumarchaeota 651137|Thaumarchaeota C 4 iron, 4 sulfur cluster binding - - - - - - - - - - - - - k59_810234_1 339670.Bamb_1990 5.67e-31 116.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2VJWP@28216|Betaproteobacteria,1K5UH@119060|Burkholderiaceae 28216|Betaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k59_810234_2 339670.Bamb_1991 3.54e-78 235.0 28M6M@1|root,2ZAK8@2|Bacteria,1R641@1224|Proteobacteria,2VZX7@28216|Betaproteobacteria,1K53C@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - k59_560090_1 983545.Glaag_4580 2.34e-29 120.0 COG1450@1|root,COG1450@2|Bacteria,1NQ25@1224|Proteobacteria,1S00D@1236|Gammaproteobacteria 1236|Gammaproteobacteria NU Type II secretory pathway, component PulD - - - - - - - - - - - - Secretin k59_118387_1 1500890.JQNL01000001_gene3135 3.15e-15 74.3 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,1X3IE@135614|Xanthomonadales 135614|Xanthomonadales NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg k59_118387_2 1163408.UU9_02019 3.47e-40 138.0 COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,1S41X@1236|Gammaproteobacteria,1X4KG@135614|Xanthomonadales 135614|Xanthomonadales NT Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis cheD - 3.5.1.44 ko:K03411 ko02030,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheD k59_1010460_2 436308.Nmar_0813 2.41e-05 44.3 arCOG08722@1|root,arCOG08722@2157|Archaea,41SSI@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_1461772_1 1234364.AMSF01000053_gene1306 4.36e-93 276.0 COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,1RNQE@1236|Gammaproteobacteria,1X54N@135614|Xanthomonadales 135614|Xanthomonadales C NADH dehydrogenase NAD(P)H nitroreductase - - - ko:K09019 ko00240,ko01100,map00240,map01100 - R09289 RC00087 ko00000,ko00001,ko01000 - - - Nitroreductase k59_910475_2 1448139.AI20_05235 2.9e-92 277.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1Y429@135624|Aeromonadales 135624|Aeromonadales F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C k59_1160962_1 1380394.JADL01000008_gene3476 2.02e-88 288.0 COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1Q44M@1224|Proteobacteria,2V6EC@28211|Alphaproteobacteria,2JQ16@204441|Rhodospirillales 204441|Rhodospirillales CEH Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2 k59_611263_1 1123261.AXDW01000002_gene1675 1.26e-56 197.0 COG1289@1|root,COG1289@2|Bacteria,1MX9H@1224|Proteobacteria,1RSD7@1236|Gammaproteobacteria,1X46U@135614|Xanthomonadales 135614|Xanthomonadales S Fusaric acid resistance protein - - - - - - - - - - - - FUSC k59_868878_2 1229909.NSED_04020 3.58e-28 105.0 COG1522@1|root,arCOG01580@2157|Archaea,41T4E@651137|Thaumarchaeota 651137|Thaumarchaeota K helix_turn_helix ASNC type - - - - - - - - - - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type k59_11672_1 543913.D521_0747 5.25e-64 197.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,1KPVD@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 k59_1517338_2 1476876.JOJO01000007_gene2360 1.05e-12 66.6 COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria 201174|Actinobacteria J LemA family - - - ko:K03744 - - - - ko00000 - - - LemA k59_1378436_1 1545915.JROG01000001_gene276 1.57e-12 72.8 COG4773@1|root,COG4773@2|Bacteria,1QURT@1224|Proteobacteria,2TW53@28211|Alphaproteobacteria,2K0HG@204457|Sphingomonadales 204457|Sphingomonadales P receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k59_1467545_1 436308.Nmar_1232 2.46e-69 211.0 arCOG08718@1|root,arCOG08718@2157|Archaea,41T2G@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - ko:K07043 - - - - ko00000 - - - - k59_816427_1 10710.EA85_LAMBD 6.96e-06 44.7 4QEU6@10239|Viruses,4QX6F@35237|dsDNA viruses no RNA stage,4QRUU@28883|Caudovirales,4QM99@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - k59_816427_2 525379.HMPREF0819_1780 3.98e-128 364.0 COG1196@1|root,COG1196@2|Bacteria,1VVD6@1239|Firmicutes 1239|Firmicutes D Ead/Ea22-like protein - - - - - - - - - - - - Ead_Ea22 k59_878018_1 1385517.N800_11540 5.15e-44 155.0 COG0457@1|root,COG0457@2|Bacteria,1R8RA@1224|Proteobacteria,1TD4F@1236|Gammaproteobacteria,1XA3V@135614|Xanthomonadales 135614|Xanthomonadales S Tetratricopeptide repeat - - - - - - - - - - - - - k59_1578690_1 1163409.UUA_05652 2.39e-158 451.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1X47D@135614|Xanthomonadales 135614|Xanthomonadales E Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine metX GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 k59_1578690_2 326297.Sama_0247 1.07e-05 49.7 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,2Q9S6@267890|Shewanellaceae 1236|Gammaproteobacteria O SMART Tetratricopeptide domain protein ccmI - - ko:K02200 - - - - ko00000 - - - TPR_16,TPR_19,TPR_2 k59_17572_2 391615.ABSJ01000030_gene791 2.2e-10 57.8 COG2018@1|root,COG2018@2|Bacteria,1QV3M@1224|Proteobacteria,1T270@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Roadblock/LC7 domain - - - - - - - - - - - - - k59_317462_1 525254.HMPREF0072_0190 5.02e-62 206.0 COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,247ME@186801|Clostridia,22FZD@1570339|Peptoniphilaceae 186801|Clostridia L cog cog3547 - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 k59_278112_1 1229909.NSED_04525 4.96e-93 278.0 COG0785@1|root,arCOG02398@2157|Archaea,41SZE@651137|Thaumarchaeota 651137|Thaumarchaeota O cytochrome c biogenesis protein - - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD k59_878332_1 402626.Rpic_1447 8.22e-91 286.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,1JZX3@119060|Burkholderiaceae 28216|Betaproteobacteria I 3-hydroxyacyl-coa dehydrogenase fadB - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 k59_715750_1 1500893.JQNB01000001_gene1943 2.18e-154 460.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,1RMQA@1236|Gammaproteobacteria,1X3B5@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_878343_1 1001585.MDS_4655 2.4e-152 435.0 COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,1RYNM@1236|Gammaproteobacteria,1YFGQ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria EQ Peptidase family S58 dmpA - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 k59_1117218_1 745411.B3C1_01335 6.63e-90 273.0 COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1J542@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S flavoproteins yhiN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07007 - - - - ko00000 - - - HI0933_like k59_1517785_1 1163408.UU9_04037 8.47e-36 130.0 2B8ZS@1|root,322AE@2|Bacteria,1RJSV@1224|Proteobacteria,1S5YF@1236|Gammaproteobacteria,1X74X@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_1517785_2 1109445.AGSX01000030_gene3168 2.97e-08 55.5 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RX58@1236|Gammaproteobacteria,1Z3RP@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - CHASE4,EAL,GGDEF k59_178068_1 314264.ROS217_00125 3.36e-16 74.7 COG3631@1|root,COG3631@2|Bacteria,1RISB@1224|Proteobacteria,2UAAK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL k59_178068_2 1323663.AROI01000008_gene2466 4.07e-46 155.0 COG5285@1|root,COG5285@2|Bacteria,1MXBX@1224|Proteobacteria 1224|Proteobacteria Q Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - - - - - - - - - - PhyH k59_278323_1 767434.Fraau_2002 1.22e-92 290.0 COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,1RPY8@1236|Gammaproteobacteria,1X47V@135614|Xanthomonadales 135614|Xanthomonadales M Protein of unknown function (DUF1302) - - - - - - - - - - - - DUF1302 k59_665929_1 641147.HMPREF9021_02711 8.19e-19 91.7 COG1074@1|root,COG1074@2|Bacteria,1QUUZ@1224|Proteobacteria,2WI1S@28216|Betaproteobacteria 28216|Betaproteobacteria L PDDEXK-like domain of unknown function (DUF3799) - - - - - - - - - - - - DUF3799 k59_665929_2 371042.NG99_16970 1.26e-16 86.3 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RR0U@1236|Gammaproteobacteria 1236|Gammaproteobacteria L helicase - - - - - - - - - - - - Helicase_C,ResIII k59_665933_1 1439940.BAY1663_03855 3.94e-111 345.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria 1236|Gammaproteobacteria E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - iECIAI39_1322.ECIAI39_3318 GDC-P k59_278363_1 666685.R2APBS1_3447 2.33e-101 303.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,1RMFM@1236|Gammaproteobacteria,1X3D0@135614|Xanthomonadales 135614|Xanthomonadales L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH k59_66600_1 745411.B3C1_08876 2.8e-113 332.0 COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1J57V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate pyrC GO:0003674,GO:0003824,GO:0004151,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - iSBO_1134.SBO_2002,iYL1228.KPN_01074 Amidohydro_1 k59_1166438_2 436308.Nmar_1404 7e-36 124.0 arCOG08702@1|root,arCOG08702@2157|Archaea,41ST2@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_1579276_1 998088.B565_0390 6.09e-48 162.0 COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1Y3J3@135624|Aeromonadales 135624|Aeromonadales E Belongs to the peptidase M20A family. ArgE subfamily argE - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k59_1218621_1 195250.CM001776_gene2659 1.06e-77 247.0 COG1171@1|root,COG1171@2|Bacteria,1G22X@1117|Cyanobacteria,1GZ4N@1129|Synechococcus 1117|Cyanobacteria E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - iJN678.ilvA PALP,Thr_dehydrat_C k59_1316592_1 880072.Desac_2842 1.04e-85 262.0 COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,42MUE@68525|delta/epsilon subdivisions,2WJFZ@28221|Deltaproteobacteria,2MR9K@213462|Syntrophobacterales 28221|Deltaproteobacteria L Integrase core domain - - - ko:K07497 - - - - ko00000 - - - rve k59_128610_2 1234364.AMSF01000095_gene2596 1.41e-85 259.0 COG2353@1|root,COG2353@2|Bacteria,1RHEW@1224|Proteobacteria,1S6XG@1236|Gammaproteobacteria,1X60U@135614|Xanthomonadales 135614|Xanthomonadales S Belongs to the UPF0312 family - - - - - - - - - - - - YceI k59_1316663_1 1528106.JRJE01000020_gene2268 2.44e-61 212.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2JPKT@204441|Rhodospirillales 204441|Rhodospirillales U Efflux pump acrB - - ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran k59_878837_1 1234364.AMSF01000064_gene2205 4.95e-152 439.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1X3ED@135614|Xanthomonadales 135614|Xanthomonadales C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 k59_817140_1 296591.Bpro_4260 1.2e-47 166.0 COG0500@1|root,COG2226@2|Bacteria,1QYJ7@1224|Proteobacteria,2VP33@28216|Betaproteobacteria 28216|Betaproteobacteria H ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_31 k59_716080_1 1163409.UUA_04233 4.38e-29 115.0 COG0659@1|root,COG0659@2|Bacteria,1MXA7@1224|Proteobacteria,1RQYD@1236|Gammaproteobacteria,1X46G@135614|Xanthomonadales 135614|Xanthomonadales P secondary active sulfate transmembrane transporter activity - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - - k59_716080_2 1384054.N790_05460 2.83e-31 113.0 COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,1S9SN@1236|Gammaproteobacteria,1X7UB@135614|Xanthomonadales 135614|Xanthomonadales S Phosphate-starvation-inducible E - - - - - - - - - - - - PsiE k59_468197_1 380703.AHA_0074 7.26e-165 476.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1Y3N5@135624|Aeromonadales 135624|Aeromonadales P Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB btuB - - ko:K16092 - - - - ko00000,ko02000 1.B.14.3 - - Plug,TonB_dep_Rec k59_666221_1 1112217.PPL19_23786 1.01e-127 399.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k59_1066556_1 1234364.AMSF01000015_gene3192 2.53e-91 291.0 COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1X36Z@135614|Xanthomonadales 135614|Xanthomonadales E 5-methyltetrahydrofolate--homocysteine methyltransferase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans k59_278804_1 987059.RBXJA2T_13919 1.17e-37 144.0 COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KJEE@119065|unclassified Burkholderiales 28216|Betaproteobacteria T GGDEF domain - - - - - - - - - - - - CHASE,EAL,GAF_2,GGDEF,PAS_4,PAS_9 k59_1579687_1 1439940.BAY1663_01536 1.95e-89 263.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C k59_1579687_2 477228.YO5_02483 2.31e-61 202.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1YZPB@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria K Participates in both transcription termination and antitermination nusA GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 k59_1417619_1 330214.NIDE0837 6.61e-106 326.0 COG2838@1|root,COG2838@2|Bacteria 2|Bacteria C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH k59_666328_1 1001585.MDS_0769 4.04e-49 162.0 2CH0A@1|root,2ZANK@2|Bacteria,1R6U4@1224|Proteobacteria,1RQ3J@1236|Gammaproteobacteria,1YIJ1@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_666328_2 1395571.TMS3_0108615 2.82e-21 92.4 COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,1RRK5@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Xanthine uracil uraA GO:0003674,GO:0005215,GO:0005350,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0006810,GO:0006855,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0015205,GO:0015210,GO:0015238,GO:0015851,GO:0015855,GO:0015857,GO:0015893,GO:0016020,GO:0016021,GO:0017144,GO:0019860,GO:0022857,GO:0031224,GO:0031226,GO:0034641,GO:0042221,GO:0042493,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072527,GO:0072529,GO:0072531,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1903791,GO:1904082 - ko:K02824,ko:K09016 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2,2.A.40.1.3 - iECO103_1326.ECO103_1052,iECUMN_1333.ECUMN_1189,iSFxv_1172.SFxv_2795,iS_1188.S2690 Xan_ur_permease k59_279039_1 994479.GL877878_gene1508 3.24e-34 135.0 COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,2GIZF@201174|Actinobacteria,4DYN9@85010|Pseudonocardiales 201174|Actinobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_9,Peripla_BP_3 k59_279039_2 1163408.UU9_01434 7.95e-36 130.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,1X3M7@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 k59_1267536_1 987059.RBXJA2T_10059 2.63e-96 292.0 COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,1KJ2B@119065|unclassified Burkholderiales 28216|Betaproteobacteria E Belongs to the argininosuccinate synthase family. Type 2 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth k59_766315_1 1163407.UU7_07148 3.7e-157 451.0 COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1X4F0@135614|Xanthomonadales 135614|Xanthomonadales F Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - HD,PolyA_pol,PolyA_pol_RNAbd k59_468420_1 1234364.AMSF01000037_gene126 1.21e-24 107.0 COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,1X3BD@135614|Xanthomonadales 135614|Xanthomonadales E Transglutaminase/protease-like homologues - - 2.3.2.13 ko:K22452 - - - - ko00000,ko01000 - - - DUF3488,DUF4129,Transglut_core k59_1580041_1 1109445.AGSX01000130_gene2834 1.88e-101 309.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1Z1PR@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family actP GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006846,GO:0006847,GO:0006855,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015123,GO:0015238,GO:0015318,GO:0015654,GO:0015698,GO:0015710,GO:0015711,GO:0015718,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035433,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - iB21_1397.B21_03899,iECBD_1354.ECBD_3965,iECD_1391.ECD_03939 SSF k59_1468534_1 1042377.AFPJ01000015_gene1592 2.39e-98 306.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,465EX@72275|Alteromonadaceae 1236|Gammaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase k59_129266_1 666685.R2APBS1_2689 1.73e-84 266.0 COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,1RP4F@1236|Gammaproteobacteria,1X5JE@135614|Xanthomonadales 135614|Xanthomonadales CO cytochrome c biogenesis protein - - - - - - - - - - - - AhpC-TSA,DsbD,Redoxin k59_391507_1 1234364.AMSF01000075_gene1964 6.11e-86 266.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1X34E@135614|Xanthomonadales 135614|Xanthomonadales E aminopeptidase pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 k59_1298316_1 1229909.NSED_05195 2.69e-24 94.4 COG4901@1|root,arCOG04327@2157|Archaea,41SUF@651137|Thaumarchaeota 651137|Thaumarchaeota J S25 ribosomal protein - - - ko:K02975 ko03010,map03010 M00177,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S25 k59_1298316_2 436308.Nmar_0929 1.89e-37 126.0 arCOG05330@1|root,arCOG05330@2157|Archaea,41SUC@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_445739_1 3988.XP_002538134.1 7.45e-46 150.0 2CXZ3@1|root,2S0V7@2759|Eukaryota 2759|Eukaryota T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C k59_445739_2 1301098.PKB_0792 2.17e-26 106.0 COG0840@1|root,COG0840@2|Bacteria,1NCMF@1224|Proteobacteria,1RRP8@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal k59_945512_1 663932.KB902575_gene3139 3.87e-119 355.0 COG4099@1|root,COG4099@2|Bacteria,1R7FZ@1224|Proteobacteria,2U53D@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Prolyl oligopeptidase family - - - - - - - - - - - - Peptidase_S9 k59_445772_1 393595.ABO_2752 1.04e-31 125.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1XI7M@135619|Oceanospirillales 135619|Oceanospirillales J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N k59_847415_1 1122604.JONR01000001_gene2008 3.13e-30 115.0 COG0492@1|root,COG0492@2|Bacteria,1MW14@1224|Proteobacteria,1SMJN@1236|Gammaproteobacteria,1X4B0@135614|Xanthomonadales 135614|Xanthomonadales O Pyridine nucleotide-disulphide oxidoreductase - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_3 k59_1547670_1 1245471.PCA10_09040 1.92e-57 191.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1YCUQ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P Bacterial extracellular solute-binding protein potF - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_8 k59_1347740_1 710696.Intca_0098 3.49e-72 229.0 COG2382@1|root,COG2382@2|Bacteria,2I844@201174|Actinobacteria,4FE3S@85021|Intrasporangiaceae 201174|Actinobacteria P Putative esterase - - - ko:K07214 - - - - ko00000 - - - DUF3327,Esterase k59_547494_1 745411.B3C1_05175 4.32e-11 62.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1JC1X@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K02031,ko:K02032,ko:K13896 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY k59_547494_2 745411.B3C1_05180 1.25e-91 275.0 COG4171@1|root,COG4171@2|Bacteria,1QUAT@1224|Proteobacteria,1T1RQ@1236|Gammaproteobacteria,1JC2P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V N-terminal TM domain of oligopeptide transport permease C sapC - - ko:K12370,ko:K19228 ko01503,ko02010,map01503,map02010 M00324,M00739 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.5 - - BPD_transp_1,OppC_N k59_97092_1 1034808.GIG_03799 6.07e-31 111.0 COG0048@1|root,COG0048@2|Bacteria,3WTGE@544448|Tenericutes 544448|Tenericutes J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL - - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 k59_97092_2 1162668.LFE_0878 1.33e-24 97.1 COG0049@1|root,COG0049@2|Bacteria,3J0HK@40117|Nitrospirae 40117|Nitrospirae J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 k59_1099430_1 190486.XAC0710 2.67e-72 230.0 COG4299@1|root,COG4299@2|Bacteria,1R5FB@1224|Proteobacteria,1S1E0@1236|Gammaproteobacteria,1X3EW@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1624) - - - - - - - - - - - - DUF1624 k59_1099430_2 767434.Fraau_2420 5.09e-91 280.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1X453@135614|Xanthomonadales 135614|Xanthomonadales J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C k59_1298839_1 1001585.MDS_4386 2.11e-42 147.0 COG2258@1|root,COG2258@2|Bacteria,1RAPM@1224|Proteobacteria,1RRB8@1236|Gammaproteobacteria,1YE6X@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S 3-alpha domain yiiM GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0098754 - - - - - - - - - - 3-alpha,MOSC k59_945865_1 767434.Fraau_3267 0.000201 42.7 COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,1SD3J@1236|Gammaproteobacteria,1X471@135614|Xanthomonadales 135614|Xanthomonadales D Cell division protein - - - - - - - - - - - - SPOR k59_547770_1 666685.R2APBS1_2999 2.95e-63 209.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1T1IW@1236|Gammaproteobacteria,1X3YG@135614|Xanthomonadales 135614|Xanthomonadales T Fis family transcriptional regulator fleQ - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - FleQ,HTH_8,Sigma54_activat k59_547770_2 666685.R2APBS1_3000 3.27e-21 89.4 2EJ60@1|root,337WG@2|Bacteria,1N9QH@1224|Proteobacteria,1T8TU@1236|Gammaproteobacteria,1X80G@135614|Xanthomonadales 135614|Xanthomonadales S Atypical PilZ domain, cyclic di-GMP receptor - - - - - - - - - - - - PilZ_2 k59_902803_1 545276.KB898728_gene177 4.76e-26 111.0 COG3221@1|root,COG5001@1|root,COG3221@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF,PAS_9,Phosphonate-bd,Response_reg k59_104560_1 1234364.AMSF01000086_gene2850 5.51e-119 348.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1X3B7@135614|Xanthomonadales 135614|Xanthomonadales J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C k59_204591_1 553973.CLOHYLEM_03940 4.41e-47 165.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,21YCZ@1506553|Lachnoclostridium 186801|Clostridia E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ k59_1453683_1 1123060.JONP01000032_gene1866 5.63e-58 190.0 COG2084@1|root,COG2084@2|Bacteria,1PU4S@1224|Proteobacteria,2TT0X@28211|Alphaproteobacteria 28211|Alphaproteobacteria I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 k59_752754_1 1380391.JIAS01000014_gene2173 3.37e-05 45.8 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria,2JSE3@204441|Rhodospirillales 204441|Rhodospirillales C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k59_752754_2 204773.HEAR3276 6.19e-42 143.0 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2VSEK@28216|Betaproteobacteria,474CT@75682|Oxalobacteraceae 28216|Betaproteobacteria K Sigma-70, region 4 rpoE8 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 k59_855093_1 323848.Nmul_A0857 3.42e-130 398.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,371W3@32003|Nitrosomonadales 28216|Betaproteobacteria C dehydrogenase, E1 component sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr k59_452874_1 1234364.AMSF01000005_gene739 5.17e-95 286.0 COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,1RN5Q@1236|Gammaproteobacteria,1X3FS@135614|Xanthomonadales 135614|Xanthomonadales P Part of the ABC transporter complex PstSACB involved in phosphate import - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 k59_52537_1 1001585.MDS_4171 1.48e-33 123.0 COG2207@1|root,COG2207@2|Bacteria,1RA7U@1224|Proteobacteria,1S2Q5@1236|Gammaproteobacteria,1YDIB@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K AraC-binding-like domain benR - - - - - - - - - - - AraC_binding_2,HTH_18 k59_52537_2 644801.Psest_2699 6.25e-41 145.0 COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,1RYGT@1236|Gammaproteobacteria,1YZP4@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria P COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit benA - 1.14.12.10 ko:K05549 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110 RC00270,RC01378,RC01450,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A k59_154811_1 1114970.PSF113_4168 6.73e-28 114.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1YPF4@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria S Competence protein ComEC ycaI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B k59_1203310_1 1366050.N234_29780 5.36e-60 196.0 COG0807@1|root,COG0807@2|Bacteria,1PQ5Y@1224|Proteobacteria,2VJ66@28216|Betaproteobacteria,1KD6C@119060|Burkholderiaceae 28216|Betaproteobacteria H GTP cyclohydrolase N terminal ribA - - - - - - - - - - - GTP_CH_N,GTP_cyclohydro2 k59_302865_1 1286631.X805_16380 2.59e-75 237.0 COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VHCU@28216|Betaproteobacteria,1KK9B@119065|unclassified Burkholderiales 28216|Betaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 k59_154898_1 1144319.PMI16_04755 1.27e-22 94.4 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,4724H@75682|Oxalobacteraceae 28216|Betaproteobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA k59_154898_2 1144319.PMI16_04756 2.1e-69 220.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,473H7@75682|Oxalobacteraceae 28216|Betaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP k59_154899_1 644801.Psest_4016 1.3e-06 58.2 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1Z033@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria L Belongs to the 'phage' integrase family intS - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase k59_154899_5 1218352.B597_019620 5.92e-19 85.1 COG0629@1|root,COG0629@2|Bacteria 2|Bacteria L single-stranded DNA binding ycf41 - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB k59_154899_7 78245.Xaut_0732 7.05e-10 56.6 2E8XG@1|root,3337G@2|Bacteria,1N7HF@1224|Proteobacteria,2UFC4@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - HTH_17 k59_1503841_1 1192759.AKIB01000028_gene2022 2.11e-17 85.1 COG0845@1|root,COG0845@2|Bacteria,1RC4B@1224|Proteobacteria,2U65Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 k59_1503882_1 1234364.AMSF01000088_gene2741 3.36e-153 458.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1X3JM@135614|Xanthomonadales 135614|Xanthomonadales C Molybdopterin oxidoreductase Fe4S4 domain - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k59_1203394_1 1163407.UU7_06153 6.07e-18 90.1 COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,1X5BV@135614|Xanthomonadales 135614|Xanthomonadales U Large exoproteins involved in heme utilization or adhesion - - - - - - - - - - - - Haemagg_act k59_803020_1 62928.azo1033 6.57e-95 293.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,2KUXQ@206389|Rhodocyclales 206389|Rhodocyclales IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C k59_502692_1 1207076.ALAT01000098_gene2537 2.11e-53 178.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RQBM@1236|Gammaproteobacteria,1Z3SS@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria E Aminotransferase class I and II yfdZ GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K14261 - - - - ko00000,ko01000,ko01007 - - iEcSMS35_1347.EcSMS35_2531,iSBO_1134.SBO_2405 Aminotran_1_2 k59_52663_1 1437882.AZRU01000046_gene5124 5.56e-29 106.0 COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,1YGED@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K09888 - - - - ko00000,ko03036 - - - ZapA k59_52663_2 686578.AFFX01000010_gene2350 9.9e-22 87.8 2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SGID@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIGRFAM TIGR02449 family protein VL23_04670 - - ko:K09892 - - - - ko00000,ko03036 - - - - k59_903084_1 1459636.NTE_01667 6.14e-07 52.4 arCOG08684@1|root,arCOG08684@2157|Archaea,41T64@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_205137_1 1163617.SCD_n02478 6.48e-90 272.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria 28216|Betaproteobacteria M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC k59_953283_1 1500893.JQNB01000001_gene2285 4.13e-145 425.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1X53V@135614|Xanthomonadales 135614|Xanthomonadales T gtp-binding protein typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 k59_703126_1 745411.B3C1_05692 6e-173 499.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1J4ZV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction rep GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03656,ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_105189_1 1229909.NSED_05845 9.83e-95 300.0 COG0672@1|root,arCOG04330@2157|Archaea,41T07@651137|Thaumarchaeota 651137|Thaumarchaeota P High-affinity Fe2 Pb2 permease - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 k59_1556207_1 1390370.O203_22280 1.13e-41 155.0 COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - GAF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1 k59_205388_1 1356854.N007_04865 9.72e-07 55.8 COG0443@1|root,COG0443@2|Bacteria,1V76M@1239|Firmicutes,4IUKH@91061|Bacilli 91061|Bacilli O Heat shock 70 kDa protein - - - - - - - - - - - - StbA k59_52870_1 745411.B3C1_16345 2.97e-75 248.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_1153600_2 436308.Nmar_1704 2.53e-58 183.0 arCOG08775@1|root,arCOG08775@2157|Archaea,41T9K@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_105457_1 62928.azo3444 1.14e-80 248.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VHRM@28216|Betaproteobacteria,2KV48@206389|Rhodocyclales 206389|Rhodocyclales U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 k59_52895_2 979556.MTES_0048 3.94e-31 110.0 COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4FQ66@85023|Microbacteriaceae 201174|Actinobacteria K 'Cold-shock' DNA-binding domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD k59_52907_1 768670.Calni_1081 6.2e-10 59.3 COG0597@1|root,COG0597@2|Bacteria,2GFR7@200930|Deferribacteres 200930|Deferribacteres M This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 k59_52907_2 1089553.Tph_c12900 5.13e-18 85.5 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,42F4D@68295|Thermoanaerobacterales 186801|Clostridia J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS k59_3804_1 1538295.JY96_12895 1.95e-40 148.0 COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria,1KJ5A@119065|unclassified Burkholderiales 28216|Betaproteobacteria KLT Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,cNMP_binding k59_1203732_1 322710.Avin_17570 8.39e-110 320.0 COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,1RNXB@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit lpsI - 2.8.3.5 ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans k59_155655_1 1192868.CAIU01000006_gene496 1.25e-34 139.0 COG4625@1|root,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,43NBA@69277|Phyllobacteriaceae 28211|Alphaproteobacteria MU Autotransporter beta-domain - - - - - - - - - - - - Autotransporter,PATR k59_155723_1 436308.Nmar_1234 3.45e-211 587.0 COG0489@1|root,arCOG01846@1|root,arCOG00585@2157|Archaea,arCOG01846@2157|Archaea,41SF1@651137|Thaumarchaeota 651137|Thaumarchaeota D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA k59_155723_2 1229909.NSED_06925 2.73e-37 129.0 COG1095@1|root,arCOG00675@2157|Archaea,41SGF@651137|Thaumarchaeota 651137|Thaumarchaeota K DNA-directed RNA polymerase - - 2.7.7.6 ko:K03049 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00184 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021 - - - S1,SHS2_Rpb7-N k59_1356526_1 1229909.NSED_07470 3.56e-72 221.0 arCOG11327@1|root,arCOG11327@2157|Archaea,41T5V@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_1504344_1 745411.B3C1_16445 2.55e-50 172.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1T213@1236|Gammaproteobacteria,1J5VV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T signal transduction histidine kinase phoQ - 2.7.13.3 ko:K07637 ko01503,ko02020,map01503,map02020 M00444,M00709,M00721,M00723,M00724,M00744 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c,PhoQ_Sensor k59_353275_1 1234364.AMSF01000095_gene2612 4.74e-117 350.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RPX4@1236|Gammaproteobacteria,1X5PC@135614|Xanthomonadales 135614|Xanthomonadales E amino acid ybeC - - - - - - - - - - - AA_permease_2 k59_1303608_1 301.JNHE01000008_gene3761 4.03e-103 309.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RPU7@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM k59_1356652_1 1395571.TMS3_0124400 2.68e-130 374.0 COG0842@1|root,COG0842@2|Bacteria,1MVUG@1224|Proteobacteria,1RNF7@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Transport Permease Protein pedC - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane k59_106004_1 1448139.AI20_03875 2.99e-121 362.0 COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria 1236|Gammaproteobacteria G COG3525 N-acetyl-beta-hexosaminidase exo - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - Glyco_hydro_20,Glyco_hydro_20b k59_453565_1 1523503.JPMY01000038_gene1415 1.39e-64 207.0 COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,1SZQB@1236|Gammaproteobacteria 1236|Gammaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k59_553380_1 1122132.AQYH01000008_gene2324 2.46e-90 277.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRJ1@28211|Alphaproteobacteria,4BBGK@82115|Rhizobiaceae 28211|Alphaproteobacteria EGP Sugar (and other) transporter - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 k59_403440_1 1469245.JFBG01000057_gene2374 3.66e-65 209.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,1RNCK@1236|Gammaproteobacteria,1WW0A@135613|Chromatiales 1236|Gammaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k59_1356884_1 1234364.AMSF01000055_gene1081 6.39e-112 335.0 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1X43W@135614|Xanthomonadales 135614|Xanthomonadales E amino acid peptide transporter - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k59_303553_1 59538.XP_005968842.1 1.21e-38 137.0 COG0625@1|root,KOG0867@2759|Eukaryota,39928@33154|Opisthokonta 33154|Opisthokonta O Glutathione S-transferase, N-terminal domain - - - - - - - - - - - - GST_C,GST_C_2,GST_N k59_856570_1 1234364.AMSF01000075_gene1922 4.79e-82 262.0 COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1X3AP@135614|Xanthomonadales 135614|Xanthomonadales S Oxygen tolerance - - - - - - - - - - - - BatD k59_106239_1 1699360.A0A0K1YZY7_CVHSA 3.51e-130 411.0 4QAM0@10239|Viruses,4R10Q@439488|ssRNA viruses,4R0QR@35278|ssRNA positive-strand viruses no DNA stage,4R1N0@76804|Nidovirales 76804|Nidovirales A omega peptidase activity - GO:0000175,GO:0001172,GO:0001510,GO:0001959,GO:0001960,GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003727,GO:0003824,GO:0003968,GO:0004386,GO:0004482,GO:0004483,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006370,GO:0006396,GO:0006397,GO:0006417,GO:0006464,GO:0006508,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008171,GO:0008173,GO:0008174,GO:0008408,GO:0008757,GO:0009058,GO:0009059,GO:0009451,GO:0009452,GO:0009605,GO:0009607,GO:0009889,GO:0009892,GO:0009893,GO:0009894,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010506,GO:0010556,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0010646,GO:0010648,GO:0010952,GO:0016032,GO:0016070,GO:0016071,GO:0016462,GO:0016556,GO:0016579,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0018130,GO:0018995,GO:0019048,GO:0019049,GO:0019054,GO:0019056,GO:0019057,GO:0019058,GO:0019079,GO:0019080,GO:0019083,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0020012,GO:0023051,GO:0023057,GO:0030162,GO:0030430,GO:0030682,GO:0030683,GO:0031323,GO:0031325,GO:0031326,GO:0031329,GO:0031347,GO:0031348,GO:0032259,GO:0032268,GO:0032270,GO:0032774,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0034062,GO:0034248,GO:0034641,GO:0034654,GO:0035821,GO:0036211,GO:0036260,GO:0036265,GO:0039502,GO:0039503,GO:0039506,GO:0039507,GO:0039519,GO:0039548,GO:0039579,GO:0039604,GO:0039644,GO:0039648,GO:0039653,GO:0039656,GO:0039657,GO:0039690,GO:0039694,GO:0039713,GO:0039714,GO:0042025,GO:0042802,GO:0043085,GO:0043170,GO:0043207,GO:0043412,GO:0043414,GO:0043656,GO:0043657,GO:0044003,GO:0044068,GO:0044073,GO:0044092,GO:0044093,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044279,GO:0044359,GO:0044362,GO:0044403,GO:0044413,GO:0044414,GO:0044415,GO:0044419,GO:0044501,GO:0045088,GO:0045824,GO:0045862,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050690,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051336,GO:0051345,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051817,GO:0051832,GO:0051833,GO:0051834,GO:0052026,GO:0052027,GO:0052029,GO:0052031,GO:0052037,GO:0052055,GO:0052056,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052204,GO:0052205,GO:0052250,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052312,GO:0052493,GO:0052547,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0060338,GO:0060339,GO:0060759,GO:0060761,GO:0065007,GO:0065009,GO:0070536,GO:0070646,GO:0070647,GO:0071108,GO:0071704,GO:0075109,GO:0075111,GO:0075112,GO:0075114,GO:0075136,GO:0075528,GO:0080009,GO:0080090,GO:0080134,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097659,GO:0097747,GO:0101005,GO:0106005,GO:0140096,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1990380,GO:2000112,GO:2000152,GO:2000158,GO:2001141 - - - - - - - - - - - k59_849690_1 1198452.Jab_2c28910 7.07e-107 320.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria,472TI@75682|Oxalobacteraceae 28216|Betaproteobacteria I PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 k59_1049372_1 1234364.AMSF01000025_gene3636 5.99e-223 630.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,1X34U@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C k59_1350476_1 1336243.JAEA01000009_gene175 4.24e-51 171.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTYY@28211|Alphaproteobacteria,1JSZJ@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Alcohol dehydrogenase GroES-like domain - - - ko:K13979 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N k59_1197404_1 1163407.UU7_15710 1.22e-38 147.0 COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1X3JW@135614|Xanthomonadales 135614|Xanthomonadales T COG2199 FOG GGDEF domain - - - - - - - - - - - - EAL,GAF_2,GGDEF k59_550291_1 436308.Nmar_0770 8.14e-33 122.0 COG1759@1|root,arCOG04346@2157|Archaea,41S79@651137|Thaumarchaeota 651137|Thaumarchaeota F Domain of unknown function (DUF1297) - - 6.3.4.23 ko:K06863 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R06975 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - DUF1246,DUF1297 k59_99542_1 768671.ThimaDRAFT_1380 0.000373 42.4 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1WX7G@135613|Chromatiales 135613|Chromatiales E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC2 - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 k59_99542_2 257310.BB4854 2.87e-82 256.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,3T2YB@506|Alcaligenaceae 28216|Betaproteobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh k59_850219_1 666685.R2APBS1_2305 1.47e-38 144.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1S0CZ@1236|Gammaproteobacteria,1X55D@135614|Xanthomonadales 135614|Xanthomonadales S COG2366 Protein related to penicillin acylase - - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase k59_1197560_2 1234364.AMSF01000064_gene2189 1.27e-88 268.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1X315@135614|Xanthomonadales 135614|Xanthomonadales D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA k59_1049839_1 767434.Fraau_1778 8.22e-28 113.0 COG3537@1|root,COG3537@2|Bacteria,1MXCY@1224|Proteobacteria,1RQDD@1236|Gammaproteobacteria,1X3M0@135614|Xanthomonadales 135614|Xanthomonadales G Alpha-1,2-mannosidase - - - - - - - - - - - - Glyco_hydro_92 k59_1049839_2 1379701.JPJC01000114_gene721 1.35e-59 197.0 COG3538@1|root,COG3538@2|Bacteria,1MXZA@1224|Proteobacteria,2UNMS@28211|Alphaproteobacteria,2K0CW@204457|Sphingomonadales 28211|Alphaproteobacteria S DUF1237 - - - ko:K09704 - - - - ko00000 - - - Glyco_hydro_125 k59_395192_1 1234364.AMSF01000037_gene185 6.02e-68 211.0 COG5424@1|root,COG5424@2|Bacteria,1MXTR@1224|Proteobacteria,1T0JE@1236|Gammaproteobacteria,1XD0T@135614|Xanthomonadales 135614|Xanthomonadales H COG5424 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C - - - - - - - - - - - - Haem_oxygenas_2 k59_99756_1 999541.bgla_1g24310 2.2e-167 476.0 COG4266@1|root,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,2VKRI@28216|Betaproteobacteria,1K1GK@119060|Burkholderiaceae 28216|Betaproteobacteria F Belongs to the allantoicase family alc - 3.5.3.4 ko:K01477 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R02422 RC00379,RC00712 ko00000,ko00001,ko00002,ko01000 - - - Allantoicase k59_449170_1 1163409.UUA_10076 1.43e-41 143.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,1X3QF@135614|Xanthomonadales 135614|Xanthomonadales P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran k59_449170_2 1234364.AMSF01000005_gene735 2.24e-102 301.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1SC6F@1236|Gammaproteobacteria,1XC4U@135614|Xanthomonadales 135614|Xanthomonadales P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU k59_99831_2 1163408.UU9_10664 1.34e-87 265.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,1X4RS@135614|Xanthomonadales 135614|Xanthomonadales IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB k59_99891_1 382245.ASA_3949 8.33e-97 300.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria,1Y5AI@135624|Aeromonadales 135624|Aeromonadales T Gammaproteobacterial periplasmic sensor domain - - - ko:K18765 - - - - ko00000,ko03019 - - - EAL,GAPES4,GGDEF k59_449620_1 265072.Mfla_1934 1.06e-31 126.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria 28216|Betaproteobacteria NT chemotaxis - - - ko:K03406,ko:K03776 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal k59_449738_1 1397693.KK211187_gene822 4.44e-06 50.8 COG0454@1|root,COG0456@2|Bacteria,1V4RP@1239|Firmicutes,4IPZK@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 k59_1158522_1 1229909.NSED_00110 5.34e-176 498.0 COG1903@1|root,arCOG04383@2157|Archaea,41S70@651137|Thaumarchaeota 651137|Thaumarchaeota H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A cbiD - 2.1.1.195 ko:K02188 ko00860,ko01100,map00860,map01100 - R07773 RC00003,RC02051 ko00000,ko00001,ko01000 - - - CbiD k59_807909_1 745411.B3C1_10412 1.15e-116 345.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1J4KA@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria rmuC GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - ko:K09760 - - - - ko00000 - - - RmuC k59_458498_1 267608.RSp0710 8e-51 172.0 COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2VIA7@28216|Betaproteobacteria,1K5U4@119060|Burkholderiaceae 28216|Betaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA k59_1565645_1 1229909.NSED_01655 1.28e-05 47.4 arCOG08643@1|root,arCOG08643@2157|Archaea,41T2H@651137|Thaumarchaeota 651137|Thaumarchaeota S peptidyl-tyrosine sulfation - - - - - - - - - - - - - k59_1565645_2 1229909.NSED_01660 6.96e-54 177.0 arCOG08643@1|root,arCOG08716@1|root,arCOG08643@2157|Archaea,arCOG08716@2157|Archaea,41T3H@651137|Thaumarchaeota 651137|Thaumarchaeota S peptidyl-tyrosine sulfation - - - - - - - - - - - - - k59_308451_1 322710.Avin_38440 7.37e-151 436.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Catalyzes the reversible hydration of fumarate to (S)- malate fumA GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0033554,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0047808,GO:0048037,GO:0050163,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1778,iPC815.YPO3335 Fumerase,Fumerase_C k59_9304_1 767434.Fraau_0210 7.09e-62 206.0 COG3659@1|root,COG3659@2|Bacteria,1R71M@1224|Proteobacteria,1S128@1236|Gammaproteobacteria,1X72H@135614|Xanthomonadales 135614|Xanthomonadales M Carbohydrate-selective porin, OprB family - - - ko:K07267 - - - - ko00000,ko02000 1.B.19.1 - - OprB k59_264917_1 666685.R2APBS1_3308 6.98e-49 165.0 COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1X3FM@135614|Xanthomonadales 135614|Xanthomonadales F Belongs to the RimK family rimK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK k59_264917_2 1234364.AMSF01000058_gene908 8.83e-66 204.0 COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1X41P@135614|Xanthomonadales 135614|Xanthomonadales KT XRE family transcriptional regulator VL23_03445 - - - - - - - - - - - Response_reg,Trans_reg_C k59_458689_1 1149133.ppKF707_3342 3.56e-66 208.0 COG1737@1|root,COG1737@2|Bacteria,1N3YS@1224|Proteobacteria,1S32Z@1236|Gammaproteobacteria,1YHSM@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS k59_458689_2 1149133.ppKF707_3341 3.54e-14 70.1 COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,1RPXK@1236|Gammaproteobacteria,1YE9S@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria ET belongs to the bacterial solute-binding protein 3 family artJ_2 - - ko:K02030,ko:K09996,ko:K10014,ko:K10022 ko02010,map02010 M00226,M00229,M00235,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.1,3.A.1.3.11,3.A.1.3.3 - - SBP_bac_3 k59_1058680_1 745411.B3C1_08191 1.25e-120 357.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,1J4X4@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Catalyzes the reversible hydration of fumarate to (S)- malate fumA GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0033554,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0047808,GO:0048037,GO:0050163,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_1778,iPC815.YPO3335 Fumerase,Fumerase_C k59_1209199_1 1234364.AMSF01000024_gene3777 4.28e-158 464.0 COG3537@1|root,COG3537@2|Bacteria,1MXCY@1224|Proteobacteria,1RYV7@1236|Gammaproteobacteria,1XC59@135614|Xanthomonadales 135614|Xanthomonadales G Hydrolase - - - - - - - - - - - - Glyco_hydro_92 k59_408107_1 76114.ebA3316 3.16e-113 343.0 COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,2VMSK@28216|Betaproteobacteria,2KW15@206389|Rhodocyclales 206389|Rhodocyclales M Sulfatase - - - - - - - - - - - - Sulfatase k59_708168_1 1234364.AMSF01000025_gene3587 2.86e-98 313.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X34J@135614|Xanthomonadales 135614|Xanthomonadales V Efflux pump membrane transporter - - - ko:K18299 - M00641 - - ko00000,ko00002,ko01504,ko02000 2.A.6.2.16 - - ACR_tran k59_57832_1 1234364.AMSF01000010_gene592 1.34e-128 380.0 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1X3CQ@135614|Xanthomonadales 135614|Xanthomonadales E Transporter yhiP - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 k59_57832_2 1163407.UU7_10940 5.95e-68 209.0 COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,1SCUJ@1236|Gammaproteobacteria,1X6IP@135614|Xanthomonadales 135614|Xanthomonadales K MarR family transcriptional regulator - - - - - - - - - - - - MarR_2 k59_865401_1 666685.R2APBS1_2390 5.17e-116 347.0 COG0654@1|root,COG0654@2|Bacteria,1R7UC@1224|Proteobacteria,1S1B9@1236|Gammaproteobacteria,1X3BJ@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid kmo GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 k59_1308329_1 1449976.KALB_339 3.2e-15 74.7 COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4E02D@85010|Pseudonocardiales 201174|Actinobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.127 ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short_C2 k59_1308329_2 426117.M446_4912 8.59e-63 199.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQQG@28211|Alphaproteobacteria,1JT7P@119045|Methylobacteriaceae 28211|Alphaproteobacteria Q PFAM fumarylacetoacetate (FAA) hydrolase - - - ko:K18336 ko00051,ko01120,map00051,map01120 - R10691 RC00326,RC03236 ko00000,ko00001,ko01000 - - - FAA_hydrolase k59_215223_1 95619.PM1_0214545 3.17e-110 319.0 COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran k59_9534_1 1163407.UU7_03357 6.72e-30 110.0 COG0477@1|root,COG0477@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily yceE - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1 k59_9534_2 666685.R2APBS1_1061 2.65e-71 228.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1X4AB@135614|Xanthomonadales 135614|Xanthomonadales E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family argD - - - - - - - - - - - Aminotran_3 k59_215230_1 574966.KB898654_gene1134 4e-106 321.0 COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,1RNIZ@1236|Gammaproteobacteria,1XIBN@135619|Oceanospirillales 135619|Oceanospirillales G Belongs to the mannitol dehydrogenase family - - 1.1.1.67 ko:K00045 ko00051,map00051 - R00868 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C k59_1566049_1 666685.R2APBS1_1216 1.98e-23 98.2 COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,1RPY3@1236|Gammaproteobacteria,1X3FQ@135614|Xanthomonadales 135614|Xanthomonadales E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 k59_1566049_2 1234364.AMSF01000056_gene1193 4.08e-47 156.0 29ZC2@1|root,30MAP@2|Bacteria,1QB0H@1224|Proteobacteria,1T6HG@1236|Gammaproteobacteria,1X7HZ@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - k59_608968_1 1234364.AMSF01000075_gene1946 2.47e-110 324.0 COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,1X79T@135614|Xanthomonadales 135614|Xanthomonadales Q ABC-type transport system involved in resistance to organic solvents, periplasmic component - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD k59_865555_1 1234364.AMSF01000048_gene2045 1.35e-127 382.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1S1KH@1236|Gammaproteobacteria,1X3PX@135614|Xanthomonadales 135614|Xanthomonadales S Glutaryl-7-ACA acylase - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 k59_215306_2 521674.Plim_4265 0.000328 48.1 29XN2@1|root,30JDF@2|Bacteria,2J498@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - k59_558216_1 396588.Tgr7_1416 2.85e-113 345.0 28IZ9@1|root,2Z8WS@2|Bacteria,1NRVI@1224|Proteobacteria,1SK35@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - HATPase_c_3 k59_115368_1 322710.Avin_04540 9.25e-65 218.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Protein involved in outer membrane biogenesis asmA - - ko:K07289 - - - - ko00000 - - - AsmA k59_1209435_1 1229909.NSED_09475 8.11e-140 405.0 COG0531@1|root,arCOG00009@2157|Archaea,41SXX@651137|Thaumarchaeota 651137|Thaumarchaeota E amino acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 k59_1008569_1 1448139.AI20_17915 4.17e-135 383.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1Y3MX@135624|Aeromonadales 135624|Aeromonadales J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 k59_808363_1 1234364.AMSF01000082_gene2969 5.18e-08 53.5 COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1SXR6@1236|Gammaproteobacteria,1X6MA@135614|Xanthomonadales 135614|Xanthomonadales NT Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) - - - ko:K03414 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheZ k59_808363_2 1234364.AMSF01000082_gene2970 5.9e-69 210.0 COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,1S47I@1236|Gammaproteobacteria,1X6DI@135614|Xanthomonadales 135614|Xanthomonadales KT response regulator cheY2 - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg k59_1058954_1 95619.PM1_0223955 7.52e-39 139.0 COG2207@1|root,COG2207@2|Bacteria,1QUXX@1224|Proteobacteria,1RSPT@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator feaR GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0045893,GO:0045935,GO:0046185,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051596,GO:0060255,GO:0061727,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K14063 - - - - ko00000,ko03000 - - - AraC_binding_2,HTH_18 k59_1058954_2 1123020.AUIE01000005_gene4456 5.48e-13 67.0 COG0663@1|root,COG0663@2|Bacteria,1MVUI@1224|Proteobacteria,1RYPQ@1236|Gammaproteobacteria,1YDSZ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Bacterial transferase hexapeptide (six repeats) caiE GO:0003674,GO:0003824,GO:0006575,GO:0006577,GO:0006807,GO:0008150,GO:0008152,GO:0008735,GO:0009437,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0016829,GO:0016835,GO:0016836,GO:0034641,GO:0044237,GO:0071704,GO:0097164,GO:1901564 - ko:K02617,ko:K08279 - - - - ko00000 - - - Hexapep k59_1058973_1 745411.B3C1_12989 3.61e-92 291.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RPM5@1236|Gammaproteobacteria,1J4UC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Domain of unknown function (DUF1974) fadE - 1.3.8.7 ko:K00249,ko:K06445 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974 k59_58079_1 1234364.AMSF01000015_gene3111 1.04e-20 87.0 COG0746@1|root,COG0746@2|Bacteria,1PJ8G@1224|Proteobacteria,1T6R6@1236|Gammaproteobacteria,1X7YT@135614|Xanthomonadales 135614|Xanthomonadales H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor - - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 k59_58079_2 1163408.UU9_06289 3.3e-67 208.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1X6FA@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoaC k59_865816_1 859657.RPSI07_1486 9.24e-15 76.6 COG4540@1|root,COG4540@2|Bacteria,1N2WK@1224|Proteobacteria,2VV8T@28216|Betaproteobacteria,1K8Z4@119060|Burkholderiaceae 28216|Betaproteobacteria S Baseplate assembly - - - - - - - - - - - - Phage_base_V k59_865816_2 1005995.GTPT_2528 0.000481 47.4 2ER5U@1|root,33IRE@2|Bacteria,1NJNF@1224|Proteobacteria,1SZPU@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_865816_3 391038.Bphy_1891 0.000907 46.6 2DMPX@1|root,32SY7@2|Bacteria,1NJ2H@1224|Proteobacteria,2WDXA@28216|Betaproteobacteria,1KBVZ@119060|Burkholderiaceae 28216|Betaproteobacteria S Prophage minor tail protein Z (GPZ) - - - - - - - - - - - - Minor_tail_Z k59_1366398_1 999541.bgla_2g21200 1.7e-69 234.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,1K0BR@119060|Burkholderiaceae 28216|Betaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 k59_408430_1 42565.FP66_14315 3.28e-36 140.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHGD@135619|Oceanospirillales 135619|Oceanospirillales T signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - - - - - - - - - - CBS,EAL,GGDEF,PAS_9 k59_1108858_1 1151127.KB906342_gene1135 7.91e-06 53.9 COG2911@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS k59_1566552_1 767434.Fraau_0674 8.45e-23 89.7 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,1X6HE@135614|Xanthomonadales 135614|Xanthomonadales J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p k59_1566552_2 1234364.AMSF01000027_gene3518 2.36e-103 301.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1X3Q7@135614|Xanthomonadales 135614|Xanthomonadales J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 k59_1308715_1 1234364.AMSF01000013_gene648 6.75e-117 345.0 COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,1RRBP@1236|Gammaproteobacteria,1X39F@135614|Xanthomonadales 135614|Xanthomonadales C glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD k59_165685_1 1122963.AUHB01000010_gene1504 5.13e-40 139.0 COG2021@1|root,COG2021@2|Bacteria,1RDEH@1224|Proteobacteria,2U267@28211|Alphaproteobacteria,36YBC@31993|Methylocystaceae 28211|Alphaproteobacteria E TAP-like protein - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 k59_265812_1 1163408.UU9_04529 1.12e-113 334.0 COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,1RS0W@1236|Gammaproteobacteria,1X3G2@135614|Xanthomonadales 135614|Xanthomonadales O ABC-type sulfate transport system permease component cysU - - ko:K02046 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 - - BPD_transp_1 k59_265812_2 1227349.C170_06354 1.01e-08 55.8 COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,4HD5R@91061|Bacilli,26S1S@186822|Paenibacillaceae 91061|Bacilli P Sulfate transporter subunit sbp - - ko:K02048 ko00920,ko02010,map00920,map02010 M00185 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.1,3.A.1.6.3 - - SBP_bac_11 k59_1566657_2 644801.Psest_3259 2.84e-72 227.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1Z29T@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089 Glyco_tran_28_C,Glyco_transf_28 k59_1566663_1 1234364.AMSF01000077_gene1873 9.03e-58 196.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1X3KX@135614|Xanthomonadales 135614|Xanthomonadales NT chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - Cache_3-Cache_2,MCPsignal,PAS_8 k59_215862_1 1123073.KB899243_gene607 3.96e-19 85.5 COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,1X37Z@135614|Xanthomonadales 135614|Xanthomonadales G Catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate gph GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.105 ko:K22292 ko00520,map00520 - R11785 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 k59_215862_2 1234364.AMSF01000056_gene1165 9.93e-122 351.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1X4AM@135614|Xanthomonadales 135614|Xanthomonadales H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23 k59_508420_1 330214.NIDE2759 5.02e-60 191.0 COG0528@1|root,COG0528@2|Bacteria,3J0BE@40117|Nitrospirae 40117|Nitrospirae F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase k59_508420_2 330214.NIDE2758 4.74e-75 228.0 COG0264@1|root,COG0264@2|Bacteria,3J0I2@40117|Nitrospirae 40117|Nitrospirae J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS k59_215944_1 436308.Nmar_0495 7.65e-126 369.0 COG0719@1|root,arCOG01715@2157|Archaea,41S5W@651137|Thaumarchaeota 651137|Thaumarchaeota O FeS assembly protein SufB - - - ko:K09014 - - - - ko00000 - - - UPF0051 k59_1159395_1 1454004.AW11_02432 2.86e-14 77.0 COG0438@1|root,COG0438@2|Bacteria,1MWYH@1224|Proteobacteria 1224|Proteobacteria M Glycosyl transferase group 1 wcaC GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035250,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - ko:K13684 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 k59_58434_1 745411.B3C1_14233 4.86e-88 265.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,1J5W2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family plsC GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042171,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase k59_555451_1 1229909.NSED_00035 4.6e-85 255.0 COG0518@1|root,arCOG00087@2157|Archaea,41SQR@651137|Thaumarchaeota 651137|Thaumarchaeota F glutamine amidotransferase - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase k59_1055958_1 1163409.UUA_13180 5.53e-127 374.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RMAD@1236|Gammaproteobacteria,1X3U7@135614|Xanthomonadales 135614|Xanthomonadales V Multidrug resistance efflux pump emrA - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k59_210122_1 547045.NEISICOT_02951 6.01e-14 70.1 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria,2KQYH@206351|Neisseriales 206351|Neisseriales F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin k59_110085_1 1207076.ALAT01000185_gene2642 3.97e-43 154.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,1Z1ST@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria I COG1960 Acyl-CoA dehydrogenases HA62_19490 - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N k59_1206232_1 666685.R2APBS1_3745 1.82e-113 355.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X49G@135614|Xanthomonadales 135614|Xanthomonadales V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K07788,ko:K21133 ko02020,map02020 M00648,M00822 - - ko00000,ko00001,ko00002,ko02000 2.A.6.2,2.A.6.2.35 - - ACR_tran k59_355464_1 640081.Dsui_0112 1.38e-70 227.0 COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria,2KU89@206389|Rhodocyclales 206389|Rhodocyclales KLT serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,cNMP_binding k59_1456987_1 745411.B3C1_06428 5.61e-63 196.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,1J62V@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria K Belongs to the UPF0301 (AlgH) family yqgE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 k59_1456987_2 745411.B3C1_06408 2.42e-13 68.2 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1J4CV@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Belongs to the prokaryotic GSH synthase family gshB GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_3410,iECP_1309.ECP_2941 GSH-S_ATP,GSH-S_N k59_1360932_1 331869.BAL199_27026 3.25e-103 308.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS4J@28211|Alphaproteobacteria,4BPUP@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP k59_1206271_1 1234364.AMSF01000037_gene95 5.21e-151 445.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1X2Y0@135614|Xanthomonadales 135614|Xanthomonadales CP NADH ubiquinone oxidoreductase subunit nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N k59_1360951_1 573.JG24_11730 8.55e-10 58.2 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria C belongs to the aldehyde dehydrogenase family yneI GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0032787,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097164,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79 ko:K00135,ko:K08324 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - iECUMN_1333.ECUMN_1793 Aldedh k59_1360951_2 324057.Pjdr2_5198 4.35e-56 183.0 COG4122@1|root,COG4122@2|Bacteria,1V4A3@1239|Firmicutes,4HBCN@91061|Bacilli,26RXV@186822|Paenibacillaceae 91061|Bacilli S O-methyltransferase mdmC1 - - - - - - - - - - - Methyltransf_3 k59_1360989_1 1163407.UU7_05429 3.93e-91 273.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,1X3R8@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf k59_1156122_1 305700.B447_05263 3.1e-65 213.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,2KV3Y@206389|Rhodocyclales 206389|Rhodocyclales M zinc metalloprotease - - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 k59_606012_1 1163398.AJJP01000134_gene3816 1.73e-14 68.2 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Recycling of diacylglycerol produced during the turnover of membrane phospholipid dgkA - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar k59_606012_2 1123020.AUIE01000006_gene4113 4.33e-131 374.0 COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,1RU35@1236|Gammaproteobacteria,1YEUI@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria K helix_turn_helix, Lux Regulon tcsR - - - - - - - - - - - GerE,Response_reg k59_1206334_1 1234364.AMSF01000068_gene2145 7.78e-79 240.0 COG2995@1|root,COG2995@2|Bacteria,1RAQ9@1224|Proteobacteria,1SBDT@1236|Gammaproteobacteria,1X6U5@135614|Xanthomonadales 135614|Xanthomonadales S paraquat-inducible protein A - - - ko:K03808 - - - - ko00000 - - - PqiA k59_1206334_2 1163408.UU9_16086 7.4e-28 107.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1X37Y@135614|Xanthomonadales 135614|Xanthomonadales O Thioredoxin - - - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin k59_55413_1 1071679.BG57_10650 5.65e-166 470.0 COG0329@1|root,COG0329@2|Bacteria,1MUNF@1224|Proteobacteria,2VH4S@28216|Betaproteobacteria,1JZRT@119060|Burkholderiaceae 28216|Betaproteobacteria EM Belongs to the DapA family kdgD - 4.2.1.41 ko:K01707 ko00053,ko01100,map00053,map01100 - R02279 RC00678 ko00000,ko00001,ko01000 - - - DHDPS k59_1164533_1 83406.HDN1F_28010 1.12e-35 135.0 COG3213@1|root,COG3213@2|Bacteria,1RE7Q@1224|Proteobacteria,1S3UC@1236|Gammaproteobacteria 1236|Gammaproteobacteria P protein involved in response to NO - - - - - - - - - - - - NnrS k59_563810_1 1000569.HMPREF1040_1449 6.64e-24 106.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4H2CM@909932|Negativicutes 909932|Negativicutes L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_N,zf-CHC2 k59_1264703_1 1234364.AMSF01000036_gene257 1.08e-118 348.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1X3IG@135614|Xanthomonadales 135614|Xanthomonadales I Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA - - 1.3.8.4 ko:K00253 ko00280,ko01100,map00280,map01100 M00036 R04095 RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N k59_1515802_1 1234364.AMSF01000090_gene2454 1.5e-131 378.0 COG0209@1|root,COG0209@2|Bacteria,1P4EH@1224|Proteobacteria,1RP1A@1236|Gammaproteobacteria,1X3FG@135614|Xanthomonadales 135614|Xanthomonadales F COG0209 Ribonucleotide reductase, alpha subunit - - - - - - - - - - - - - k59_315498_1 1028801.RG1141_CH01030 4.02e-125 364.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,4BDWB@82115|Rhizobiaceae 28211|Alphaproteobacteria E Cobalamin-independent synthase, Catalytic domain metE - 2.1.1.14,4.4.1.23 ko:K00549,ko:K22363 ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230 M00017 R04405,R09365,R11897,R11899 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 k59_1114965_1 910964.GEAM_4385 6.62e-28 118.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria 1236|Gammaproteobacteria NT chemotaxis, protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,TarH k59_563881_1 436308.Nmar_1629 2.58e-09 52.8 arCOG08792@1|root,arCOG08792@2157|Archaea,41SUG@651137|Thaumarchaeota 651137|Thaumarchaeota - - - - - - - - - - - - - - - k59_563881_2 436308.Nmar_1630 4.48e-69 211.0 COG1545@1|root,arCOG01285@2157|Archaea,41SQK@651137|Thaumarchaeota 651137|Thaumarchaeota V nucleic-acid-binding protein containing a Zn-ribbon - - - ko:K07068 - - - - ko00000 - - - DUF35_N,OB_aCoA_assoc k59_225025_1 748247.AZKH_2569 1.59e-70 224.0 COG0330@1|root,COG0330@2|Bacteria,1MWMD@1224|Proteobacteria,2VKGC@28216|Betaproteobacteria,2KY8X@206389|Rhodocyclales 206389|Rhodocyclales O prohibitin homologues - - - - - - - - - - - - Band_7 k59_1575910_1 380358.XALC_0087 7.87e-103 327.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,1RMTG@1236|Gammaproteobacteria,1X5IP@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor - - - - - - - - - - - - Plug,TonB_dep_Rec k59_275259_1 1112217.PPL19_09812 1.36e-27 106.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM k59_275259_2 330214.NIDE0243 1.23e-29 112.0 COG0560@1|root,COG0560@2|Bacteria 2|Bacteria E Phosphoserine phosphatase - - - - - - - - - - - - HAD,NAD_binding_4,Sterile k59_225118_1 575586.HMPREF0016_02597 1.21e-60 199.0 COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,3NJEF@468|Moraxellaceae 1236|Gammaproteobacteria L Reverse transcriptase (RNA-dependent DNA polymerase) - - - - - - - - - - - - GIIM,RVT_1 k59_1164676_1 1234364.AMSF01000095_gene2562 9.08e-80 249.0 COG0845@1|root,COG0845@2|Bacteria,1NQDN@1224|Proteobacteria,1RRFE@1236|Gammaproteobacteria,1X3QX@135614|Xanthomonadales 135614|Xanthomonadales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family ybjY - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k59_1416137_1 1215092.PA6_035_00720 7.22e-35 135.0 COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S3Q4@1236|Gammaproteobacteria,1YG4I@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Cadherin_3,Calx-beta,HemolysinCabind,VWA,VWA_2 k59_275361_1 1163407.UU7_16507 5.54e-53 187.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,1X5HN@135614|Xanthomonadales 135614|Xanthomonadales L COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - - - - - - - - - - Helicase_C,SNF2_N k59_275361_2 1234364.AMSF01000080_gene3055 0.000293 42.4 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,1X2XQ@135614|Xanthomonadales 135614|Xanthomonadales I Glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N k59_714114_1 1187848.AJYQ01000076_gene1748 1.95e-26 105.0 COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,1RN2Z@1236|Gammaproteobacteria,1XSAG@135623|Vibrionales 135623|Vibrionales C COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins hppD - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase,Glyoxalase_5 k59_714114_2 1120956.JHZK01000013_gene2583 6.46e-36 132.0 COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,2TRFI@28211|Alphaproteobacteria,1JQHJ@119043|Rhodobiaceae 28211|Alphaproteobacteria Q homogentisate 1,2-dioxygenase hmgA - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA k59_363294_1 745411.B3C1_09777 3.39e-103 320.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1J4N3@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) mrcB GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008289,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042277,GO:0042546,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071723,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 iECIAI39_1322.ECIAI39_0153,iSBO_1134.SBO_0138,iSbBS512_1146.SbBS512_E0140,iYL1228.KPN_00164 PBP1_TM,Transgly,Transpeptidase,UB2H k59_125361_1 1163408.UU9_06884 8.47e-55 177.0 COG3038@1|root,COG3038@2|Bacteria,1REWF@1224|Proteobacteria,1S5QE@1236|Gammaproteobacteria,1XCYJ@135614|Xanthomonadales 135614|Xanthomonadales C Prokaryotic cytochrome b561 - - - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB k59_125361_2 999541.bgla_1g00180 1e-20 90.5 COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,2VGZA@28216|Betaproteobacteria,1JZQW@119060|Burkholderiaceae 28216|Betaproteobacteria C Has an organic peroxide-dependent peroxidase activity - - 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase k59_1576163_1 436308.Nmar_0041 2.9e-82 252.0 COG0083@1|root,arCOG01027@2157|Archaea,41S89@651137|Thaumarchaeota 651137|Thaumarchaeota E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB - 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N k59_615927_1 440512.C211_20767 2.01e-95 282.0 COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,1SNE4@1236|Gammaproteobacteria 1236|Gammaproteobacteria KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K02483,ko:K07666 ko02020,ko02024,map02020,map02024 M00453 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C k59_1064751_1 366649.XFF4834R_chr04670 2.55e-101 303.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1X4IM@135614|Xanthomonadales 135614|Xanthomonadales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase k59_616027_1 95619.PM1_0208850 5.52e-42 147.0 COG2988@1|root,COG2988@2|Bacteria,1MW1T@1224|Proteobacteria,1RQPG@1236|Gammaproteobacteria 1236|Gammaproteobacteria E Belongs to the AspA AstE family. Succinylglutamate desuccinylase subfamily astE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009017,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.96 ko:K05526 ko00330,ko01100,map00330,map01100 - R00411 RC00064,RC00090 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_813,iECABU_c1320.ECABU_c20010,iECED1_1282.ECED1_1946,iECOK1_1307.ECOK1_1864,iECS88_1305.ECS88_1796,iUMN146_1321.UM146_08430,iUTI89_1310.UTI89_C1939,ic_1306.c2144 AstE_AspA k59_616027_2 1226994.AMZB01000098_gene1195 6.58e-32 122.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1YCZ4@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 DHHA1,tRNA-synt_2c,tRNA_SAD k59_315958_1 1234364.AMSF01000055_gene1022 1.14e-40 139.0 COG2095@1|root,COG2095@2|Bacteria,1N689@1224|Proteobacteria,1RPV0@1236|Gammaproteobacteria,1X4BK@135614|Xanthomonadales 135614|Xanthomonadales U UPF0056 membrane protein - - - - - - - - - - - - MarC k59_315958_2 1163408.UU9_13007 4.02e-19 84.7 COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,1RNNV@1236|Gammaproteobacteria,1X3SZ@135614|Xanthomonadales 135614|Xanthomonadales IQ short-chain dehydrogenase - - - - - - - - - - - - adh_short,adh_short_C2 k59_1064917_1 1042209.HK44_007130 1.74e-70 221.0 COG3384@1|root,COG3384@2|Bacteria,1RB6Z@1224|Proteobacteria,1S1S9@1236|Gammaproteobacteria,1YMN4@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria S subunit of aromatic ring-opening dioxygenase - - - ko:K15777 ko00965,map00965 - R08836 RC00387 ko00000,ko00001,ko01000 - - - LigB k59_363502_1 1499686.BN1079_02748 1.57e-23 99.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria 1236|Gammaproteobacteria L it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction uvrD GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C k59_363502_2 287.DR97_2821 0.000198 45.1 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1YF45@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_9,Reg_prop,Y_Y_Y k59_64924_2 1229909.NSED_03910 3.2e-10 59.3 COG0640@1|root,arCOG01686@2157|Archaea 2157|Archaea K regulatory protein, arsR - - - - - - - - - - - - HTH_20,HTH_5 k59_1216819_1 1390370.O203_22275 2.7e-65 224.0 COG2202@1|root,COG2203@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RPI4@1236|Gammaproteobacteria,1YHI5@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,dCache_3 k59_564374_1 1182590.BN5_03049 1.38e-127 378.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1YE2K@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ilvI GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N k59_914663_1 33035.JPJF01000023_gene3227 0.000475 47.8 COG3292@1|root,COG3292@2|Bacteria,1UICX@1239|Firmicutes,24ABD@186801|Clostridia,3Y1BC@572511|Blautia 186801|Clostridia T Psort location Extracellular, score - - - - - - - - - - - - Big_3_3 k59_564389_1 1229909.NSED_01130 3.35e-90 273.0 COG0472@1|root,arCOG03199@2157|Archaea,41S8B@651137|Thaumarchaeota 651137|Thaumarchaeota M glycosyl transferase family - - 2.7.8.15 ko:K01001 ko00510,ko01100,map00510,map01100 M00055 R05969 RC00002 ko00000,ko00001,ko00002,ko01000,ko01003 - - - Glycos_transf_4 k59_1376848_1 1500893.JQNB01000001_gene2888 3.03e-13 74.7 COG3250@1|root,COG3250@2|Bacteria,1R32T@1224|Proteobacteria,1SF8P@1236|Gammaproteobacteria,1X8W4@135614|Xanthomonadales 135614|Xanthomonadales G Beta-1,3-glucanase - - - - - - - - - - - - F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_64 k59_363577_1 745411.B3C1_03750 1.02e-81 246.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1J584@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - iE2348C_1286.E2348C_2376 Methyltransf_23 k59_226002_1 1163409.UUA_13420 1.94e-47 162.0 COG3693@1|root,COG3693@2|Bacteria,1QWFB@1224|Proteobacteria,1T45W@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - Cellulase k59_664585_1 1101188.KI912157_gene272 0.000767 42.4 COG1853@1|root,COG1853@2|Bacteria,2GPJS@201174|Actinobacteria 201174|Actinobacteria K PFAM flavin reductase domain protein, FMN-binding - - - - - - - - - - - - Flavin_Reduct k59_664585_2 1449049.JONW01000010_gene3757 3.4e-56 186.0 COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TVNW@28211|Alphaproteobacteria,2KHW0@204458|Caulobacterales 204458|Caulobacterales P Rieske 2Fe-2S - - - - - - - - - - - - Rieske,Ring_hydroxyl_A k59_1516522_1 977880.RALTA_A1558 2.42e-09 63.5 COG5563@1|root,COG5563@2|Bacteria,1QZID@1224|Proteobacteria,2WI83@28216|Betaproteobacteria,1KIR3@119060|Burkholderiaceae 28216|Betaproteobacteria S Domain of unknown function (DUF1929) - - - - - - - - - - - - DUF1929 k59_226130_1 477228.YO5_11260 2.32e-70 219.0 COG3170@1|root,COG3170@2|Bacteria,1RDXQ@1224|Proteobacteria,1S3D9@1236|Gammaproteobacteria,1Z4FH@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 k59_514787_1 666685.R2APBS1_2704 1.26e-50 182.0 COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,1X54E@135614|Xanthomonadales 135614|Xanthomonadales M rhs family - - - - - - - - - - - - RHS_repeat k59_616589_1 322710.Avin_24510 1.82e-65 206.0 COG1230@1|root,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,1S1S4@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Co Zn Cd efflux system component - - - - - - - - - - - - Cation_efflux k59_65300_1 1395571.TMS3_0104775 2.86e-98 295.0 COG0583@1|root,COG0583@2|Bacteria,1MW1R@1224|Proteobacteria,1RQMP@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k59_564704_1 237609.PSAKL28_51630 1.88e-85 259.0 COG0583@1|root,COG0583@2|Bacteria,1MWM1@1224|Proteobacteria,1RZDI@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k59_1165391_2 436308.Nmar_0574 1.35e-29 105.0 arCOG08736@1|root,arCOG08736@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - k59_176399_1 1141663.OOC_05992 1.92e-47 162.0 COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,1S1KW@1236|Gammaproteobacteria,3ZACD@586|Providencia 1236|Gammaproteobacteria S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - - - - - - - - - - Lactamase_B,Lactamase_B_2 k59_1315374_1 1234364.AMSF01000080_gene3057 7.28e-50 159.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,1X7I6@135614|Xanthomonadales 135614|Xanthomonadales J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 k59_1315374_2 1269813.ATUL01000021_gene734 6.02e-07 47.0 COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1WZA6@135613|Chromatiales 135613|Chromatiales J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 k59_1516805_1 1234364.AMSF01000025_gene3587 1.56e-127 393.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X34J@135614|Xanthomonadales 135614|Xanthomonadales V Efflux pump membrane transporter - - - ko:K18299 - M00641 - - ko00000,ko00002,ko01504,ko02000 2.A.6.2.16 - - ACR_tran k59_876895_1 1380391.JIAS01000019_gene1308 2.02e-14 77.4 COG2114@1|root,COG2114@2|Bacteria,1MWHK@1224|Proteobacteria,2TR2J@28211|Alphaproteobacteria,2JQ73@204441|Rhodospirillales 204441|Rhodospirillales T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc k59_915138_1 436308.Nmar_0082 4.33e-69 219.0 COG2073@1|root,arCOG00651@2157|Archaea,41S83@651137|Thaumarchaeota 651137|Thaumarchaeota H Cobalamin synthesis G C-terminus - - 3.7.1.12 ko:K02189 ko00860,ko01100,map00860,map01100 - R07772 RC01545,RC02097 ko00000,ko00001,ko01000 - - - CbiG_C,CbiG_N,CbiG_mid k59_915138_2 1229909.NSED_00110 3.73e-22 94.0 COG1903@1|root,arCOG04383@2157|Archaea,41S70@651137|Thaumarchaeota 651137|Thaumarchaeota H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A cbiD - 2.1.1.195 ko:K02188 ko00860,ko01100,map00860,map01100 - R07773 RC00003,RC02051 ko00000,ko00001,ko01000 - - - CbiD k59_1315479_1 1234364.AMSF01000025_gene3649 2.83e-40 144.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1X424@135614|Xanthomonadales 135614|Xanthomonadales L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N k59_1315479_2 525146.Ddes_1970 1.76e-08 50.4 COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,42WSU@68525|delta/epsilon subdivisions,2WSI8@28221|Deltaproteobacteria,2ME07@213115|Desulfovibrionales 28221|Deltaproteobacteria J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 k59_1315482_1 883126.HMPREF9710_00834 2.5e-17 84.7 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria 28216|Betaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_9 k59_1217463_1 1205753.A989_08824 9.53e-81 263.0 COG4772@1|root,COG4772@2|Bacteria,1QU2E@1224|Proteobacteria,1T1N4@1236|Gammaproteobacteria,1X55S@135614|Xanthomonadales 135614|Xanthomonadales P receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec k59_226815_1 1005048.CFU_4065 9.71e-40 144.0 COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,473EQ@75682|Oxalobacteraceae 28216|Betaproteobacteria D Peptidase family M23 envC - - - - - - - - - - - Peptidase_M23 k59_226815_2 323848.Nmul_A1119 3.15e-49 169.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,372E5@32003|Nitrosomonadales 28216|Betaproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S41 k59_564933_1 472759.Nhal_3938 1.68e-24 102.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1WWZ0@135613|Chromatiales 135613|Chromatiales E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C k59_519931_1 1234364.AMSF01000024_gene3794 1.25e-70 230.0 COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,1RS4U@1236|Gammaproteobacteria,1X3IC@135614|Xanthomonadales 135614|Xanthomonadales G Glucoamylase and related glycosyl hydrolases - - - - - - - - - - - - Glyco_hydro_15 k59_519931_2 1234364.AMSF01000024_gene3795 3.24e-52 173.0 COG1877@1|root,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,1RNIQ@1236|Gammaproteobacteria,1X4WS@135614|Xanthomonadales 135614|Xanthomonadales G Removes the phosphate from trehalose 6-phosphate to produce free trehalose otsB - 3.1.3.12 ko:K01087 ko00500,ko01100,map00500,map01100 - R02778 RC00017 ko00000,ko00001,ko01000 - - - Trehalose_PPase k59_883857_1 439235.Dalk_2603 8.79e-56 189.0 COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,42MBD@68525|delta/epsilon subdivisions,2WJT1@28221|Deltaproteobacteria,2MI62@213118|Desulfobacterales 28221|Deltaproteobacteria E TIGRFAM peptidase T-like protein - - 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 k59_322091_1 1500890.JQNL01000001_gene454 1.84e-114 344.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,1RMYF@1236|Gammaproteobacteria,1X4BN@135614|Xanthomonadales 135614|Xanthomonadales C Cytochrome c, mono-and diheme variants family - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 k59_322091_2 767434.Fraau_1851 5.84e-12 64.7 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,1X43N@135614|Xanthomonadales 135614|Xanthomonadales E PFAM GMC oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N k59_233704_2 1110502.TMO_0043 1.94e-64 241.0 28IJ1@1|root,2Z8K0@2|Bacteria,1R5PC@1224|Proteobacteria,2V9I5@28211|Alphaproteobacteria,2JTUW@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - k59_233704_4 1472716.KBK24_0134495 7.62e-20 89.4 COG2755@1|root,COG2755@2|Bacteria,1QV1E@1224|Proteobacteria 1224|Proteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Phage_fiber_2,SASA k59_233704_10 1121943.KB900008_gene2008 1.28e-08 59.3 COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,1S6BA@1236|Gammaproteobacteria,1XM9H@135619|Oceanospirillales 135619|Oceanospirillales G Phage lysozyme - - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Phage_lysozyme k59_233704_11 1218075.BAYA01000007_gene2666 1.51e-26 107.0 2BRZ4@1|root,32KZE@2|Bacteria,1Q9VG@1224|Proteobacteria,2WCZ8@28216|Betaproteobacteria,1K8TZ@119060|Burkholderiaceae 28216|Betaproteobacteria S Bacteriophage Rz lysis protein - - - - - - - - - - - - Phage_lysis k59_233704_12 1121035.AUCH01000019_gene2884 1.24e-32 125.0 COG0582@1|root,COG0582@2|Bacteria,1NWGS@1224|Proteobacteria,2VKWM@28216|Betaproteobacteria,2KV9M@206389|Rhodocyclales 206389|Rhodocyclales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase k59_233704_20 1980924.B2ZY87_9CAUD 1.92e-54 186.0 4QG7Y@10239|Viruses,4QSFA@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - k59_1227792_1 76869.PputGB1_4202 4.49e-42 142.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1YWAK@136845|Pseudomonas putida group 1236|Gammaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N k59_1227792_2 399739.Pmen_1270 3.41e-49 160.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1YE18@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC k59_1227813_1 1470593.BW43_02546 2.1e-42 154.0 COG0477@1|root,COG0477@2|Bacteria,1QTUM@1224|Proteobacteria,1T1HT@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily ycaD_1 - - - - - - - - - - - MFS_1,Sugar_tr k59_25794_1 1234364.AMSF01000024_gene3800 6.78e-124 369.0 COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1X38N@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon k59_1525827_1 1234364.AMSF01000055_gene1037 1.19e-105 315.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X5AM@135614|Xanthomonadales 135614|Xanthomonadales O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 k59_1074219_1 1234364.AMSF01000058_gene930 8.68e-78 255.0 COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,1RPKB@1236|Gammaproteobacteria,1X6MV@135614|Xanthomonadales 135614|Xanthomonadales V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD k59_1390428_1 502025.Hoch_3152 8.12e-06 53.1 COG0664@1|root,COG0664@2|Bacteria,1N1ZG@1224|Proteobacteria,4336W@68525|delta/epsilon subdivisions,2WYCK@28221|Deltaproteobacteria,2YXD4@29|Myxococcales 28221|Deltaproteobacteria T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding k59_1024406_1 1380394.JADL01000016_gene414 6.98e-51 171.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRS8@28211|Alphaproteobacteria 28211|Alphaproteobacteria EP Binding-protein-dependent transport system inner membrane component nikB - - ko:K02033,ko:K15585 ko02010,ko02024,map02010,map02024 M00239,M00440 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 k59_1590564_1 1163409.UUA_17395 1.15e-137 417.0 COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1X45Q@135614|Xanthomonadales 135614|Xanthomonadales L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran k59_674337_1 1279038.KB907348_gene3119 1.86e-65 214.0 COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2U2TJ@28211|Alphaproteobacteria,2JQA3@204441|Rhodospirillales 204441|Rhodospirillales C COG2010 Cytochrome c, mono- and diheme variants - - 1.7.2.1,1.7.99.1 ko:K15864 ko00910,ko01120,map00910,map01120 M00529 R00143,R00783,R00785 RC00086,RC02797 ko00000,ko00001,ko00002,ko01000 - - - Cytochrom_D1,Cytochrome_CBB3 k59_674337_2 1121035.AUCH01000009_gene816 2.05e-37 128.0 COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,2KXF6@206389|Rhodocyclales 206389|Rhodocyclales C Cytochrome c - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C k59_190106_1 1245471.PCA10_52950 1.77e-111 327.0 COG0765@1|root,COG0765@2|Bacteria,1MX3E@1224|Proteobacteria,1RS0Y@1236|Gammaproteobacteria,1YE61@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 k59_190106_2 743720.Psefu_3868 2.32e-24 97.4 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,1RMX1@1236|Gammaproteobacteria,1YWPD@136845|Pseudomonas putida group 1236|Gammaproteobacteria E PFAM ABC transporter related artM_2 - 3.6.3.21 ko:K02028,ko:K02029,ko:K09972,ko:K10004,ko:K10010 ko02010,ko02020,map02010,map02020 M00230,M00232,M00234,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.17,3.A.1.3.18,3.A.1.3.19,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8 - - ABC_tran k59_924664_2 572547.Amico_1700 2.55e-05 46.2 COG2513@1|root,COG2513@2|Bacteria,3TAPQ@508458|Synergistetes 508458|Synergistetes G Phosphoenolpyruvate phosphomutase - - - - - - - - - - - - PEP_mutase k59_1390697_1 1234364.AMSF01000061_gene2098 2.47e-117 357.0 COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1X5GN@135614|Xanthomonadales 135614|Xanthomonadales KL DNA helicase dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - Helicase_C_2,ResIII k59_627513_1 375286.mma_3025 1.04e-10 62.0 2E5V3@1|root,330J8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - k59_627513_2 314285.KT71_18826 3.42e-65 219.0 28MDN@1|root,30XFA@2|Bacteria,1RE2D@1224|Proteobacteria,1S5CD@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - k59_1526098_1 323848.Nmul_A1150 9.34e-56 197.0 COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1PV5D@1224|Proteobacteria,2WB3J@28216|Betaproteobacteria,37281@32003|Nitrosomonadales 28216|Betaproteobacteria CEH PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2 k59_774532_1 3885.XP_007142843.1 4.08e-48 157.0 28JZI@1|root,2QSDY@2759|Eukaryota,37J4T@33090|Viridiplantae,3GC2Z@35493|Streptophyta,4JQS3@91835|fabids 35493|Streptophyta U Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope ycf1 - - - - - - - - - - - Ycf1 k59_774555_1 1286631.X805_37280 4.37e-70 234.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,1KIWA@119065|unclassified Burkholderiales 28216|Betaproteobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN k59_924810_1 1120919.AUBI01000002_gene1211 4.22e-78 237.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2U5GN@28211|Alphaproteobacteria,2JRVE@204441|Rhodospirillales 204441|Rhodospirillales H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX - 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein k59_1125976_1 1175306.GWL_37150 2.71e-96 300.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VJD5@28216|Betaproteobacteria,475AB@75682|Oxalobacteraceae 28216|Betaproteobacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA2 - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 k59_1424227_1 1163409.UUA_03153 1.6e-71 219.0 COG4731@1|root,COG4731@2|Bacteria,1N19Y@1224|Proteobacteria,1SBCW@1236|Gammaproteobacteria,1X71P@135614|Xanthomonadales 135614|Xanthomonadales S protein conserved in bacteria - - - - - - - - - - - - DUF2147 k59_1228412_1 1163409.UUA_08821 9.33e-14 67.8 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1X3UG@135614|Xanthomonadales 135614|Xanthomonadales A 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T k59_1228412_2 269796.Rru_A1030 1.53e-45 160.0 COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TUN5@28211|Alphaproteobacteria,2JQJZ@204441|Rhodospirillales 204441|Rhodospirillales E Amino acid permease - - - ko:K16238 - - - - ko00000,ko02000 2.A.3.5 - - AA_permease_2 k59_890551_1 745411.B3C1_03605 1.79e-40 142.0 COG0329@1|root,COG0329@2|Bacteria,1MU77@1224|Proteobacteria,1RS30@1236|Gammaproteobacteria 1236|Gammaproteobacteria EM Belongs to the DapA family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS k59_140709_1 380358.XALC_2154 8.45e-74 241.0 COG0308@1|root,COG0308@2|Bacteria,1MUV3@1224|Proteobacteria,1RS0E@1236|Gammaproteobacteria,1X34X@135614|Xanthomonadales 135614|Xanthomonadales E aminopeptidase n - - - - - - - - - - - - Big_4,Peptidase_M1 k59_424289_1 748247.AZKH_3549 1.58e-79 243.0 COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,2KV43@206389|Rhodocyclales 206389|Rhodocyclales L 3'-5' exonuclease related to the exonuclease domain of PolB - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 k59_327506_1 1437882.AZRU01000045_gene4775 1.2e-76 238.0 COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,1YDMF@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria P CorA-like Mg2+ transporter protein zntB GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - ko:K16074 - - - - ko00000,ko02000 1.A.35.4 - - CorA k59_477780_1 1234364.AMSF01000063_gene2262 2.5e-118 348.0 COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,1RMFI@1236|Gammaproteobacteria,1X3K9@135614|Xanthomonadales 135614|Xanthomonadales C NADH flavin oxidoreductase NADH oxidase nerA - - ko:K10680 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Oxidored_FMN k59_1391102_1 1163409.UUA_12625 6.68e-140 398.0 COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,1RNCX@1236|Gammaproteobacteria,1X3TJ@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 k59_240615_1 1500890.JQNL01000001_gene3524 2.03e-55 183.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,1RPPC@1236|Gammaproteobacteria 1236|Gammaproteobacteria P ABC-type Fe3 transport system, periplasmic component HA62_21480 - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6 k59_1325382_1 767434.Fraau_0439 5.53e-73 230.0 COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,1RRR2@1236|Gammaproteobacteria,1X4PR@135614|Xanthomonadales 135614|Xanthomonadales G Belongs to the IUNH family - - - - - - - - - - - - IU_nuc_hydro k59_327626_1 666685.R2APBS1_0785 2.19e-103 306.0 COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,1RMIG@1236|Gammaproteobacteria,1X47C@135614|Xanthomonadales 135614|Xanthomonadales C potassium channel beta subunit - - - - - - - - - - - - Aldo_ket_red k59_890856_2 406124.ACPC01000009_gene1359 1.06e-11 67.4 COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4HC5V@91061|Bacilli,1ZB9J@1386|Bacillus 91061|Bacilli L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD ku GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - ko:K10979 ko03450,map03450 - - - ko00000,ko00001,ko03400 - - - Ku k59_674852_1 69328.PVLB_26452 1.37e-68 226.0 COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1MWD4@1224|Proteobacteria,1RVX0@1236|Gammaproteobacteria 1236|Gammaproteobacteria CI Aldehyde dehydrogenase paaN GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016725,GO:0016726,GO:0016787,GO:0016801,GO:0016803,GO:0016822,GO:0016823,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.2.1.91,3.3.2.12 ko:K02618 ko00360,ko01120,map00360,map01120 - R09820,R09836 RC00080,RC02667 ko00000,ko00001,ko01000 - - iEC55989_1330.EC55989_1523,iECO111_1330.ECO111_1781,iECO26_1355.ECO26_1991 Aldedh,MaoC_dehydratas k59_1174677_1 1163617.SCD_n03030 4.35e-15 73.2 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria 28216|Betaproteobacteria J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG - 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB k59_370532_1 2340.JV46_15210 2.2e-35 136.0 COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1J4PG@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M N-acetylmuramoyl-L-alanine amidase amiC GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - iPC815.YPO1023,iSDY_1059.SDY_3034,iYL1228.KPN_03225 AMIN,Amidase_3,LysM k59_674936_1 436308.Nmar_0037 4.17e-93 277.0 COG0602@1|root,arCOG02173@2157|Archaea,41SGM@651137|Thaumarchaeota 651137|Thaumarchaeota O Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_12,Radical_SAM k59_525003_1 999541.bgla_1g33840 2.02e-22 95.1 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2VKP2@28216|Betaproteobacteria,1JZZS@119060|Burkholderiaceae 28216|Betaproteobacteria V PFAM secretion protein HlyD family protein - - - ko:K03543 - M00701 - - ko00000,ko00002,ko02000 8.A.1.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 k59_525003_2 1218075.BAYA01000015_gene4295 7.69e-180 516.0 COG0477@1|root,COG0477@2|Bacteria,1RGPN@1224|Proteobacteria,2VNMW@28216|Betaproteobacteria,1K0WT@119060|Burkholderiaceae 28216|Betaproteobacteria P Belongs to the major facilitator superfamily - - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 k59_240854_1 767434.Fraau_1030 2.95e-78 258.0 COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,1RPVY@1236|Gammaproteobacteria,1X3CF@135614|Xanthomonadales 135614|Xanthomonadales P Outer membrane receptor for ferrienterochelin and colicins - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec k59_825940_1 296591.Bpro_2289 8.54e-82 249.0 COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2VMB3@28216|Betaproteobacteria,4ACE3@80864|Comamonadaceae 28216|Betaproteobacteria IQ PFAM Short-chain dehydrogenase reductase SDR tsaC GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 k59_1126465_1 911239.CF149_00450 1.32e-41 153.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg k59_1126518_1 95619.PM1_0200605 1.8e-108 345.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria 1236|Gammaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 k59_972464_1 402626.Rpic_0896 6.79e-40 142.0 COG1488@1|root,COG1488@2|Bacteria,1MV8U@1224|Proteobacteria,2VGZ5@28216|Betaproteobacteria,1K2JW@119060|Burkholderiaceae 28216|Betaproteobacteria F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase k59_291595_1 1234364.AMSF01000025_gene3704 3.57e-143 421.0 COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1X4VE@135614|Xanthomonadales 135614|Xanthomonadales P Sodium:sulfate symporter transmembrane region - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C k59_1126684_1 1500893.JQNB01000001_gene927 2.65e-91 291.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1XA3G@135614|Xanthomonadales 135614|Xanthomonadales D Ftsk_gamma - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma k59_775354_1 1234364.AMSF01000015_gene3114 2.88e-64 209.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1X5HG@135614|Xanthomonadales 135614|Xanthomonadales H molybdopterin biosynthesis moeA1 - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N k59_826296_2 436308.Nmar_0231 6.92e-40 147.0 arCOG06534@1|root,arCOG06534@2157|Archaea 2157|Archaea S acid phosphatase activity - - - - - - - - - - - - He_PIG k59_1126748_1 1249627.D779_2678 0.000438 48.1 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RZ2Z@1236|Gammaproteobacteria,1X2BY@135613|Chromatiales 135613|Chromatiales T diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS k59_76012_1 1123487.KB892834_gene2960 8.2e-27 107.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,2KV12@206389|Rhodocyclales 206389|Rhodocyclales L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 k59_76012_2 1392838.AWNM01000011_gene2565 1.19e-38 143.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,3T1KC@506|Alcaligenaceae 28216|Betaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim k59_1475930_1 1500893.JQNB01000001_gene818 1.34e-115 346.0 COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,1XDA0@135614|Xanthomonadales 135614|Xanthomonadales EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - ko:K08137 - - - - ko00000,ko02000 2.A.1.1.1 - - Sugar_tr k59_891728_1 748658.KB907314_gene62 5.18e-96 288.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1WWMZ@135613|Chromatiales 135613|Chromatiales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC k59_1592011_1 426117.M446_0140 3.58e-05 47.0 COG1416@1|root,COG1416@2|Bacteria,1RBQX@1224|Proteobacteria,2U6BV@28211|Alphaproteobacteria,1JX8K@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - ko:K09004 - - - - ko00000 - - - DrsE k59_241529_1 105559.Nwat_0499 1.63e-17 86.3 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1WWCN@135613|Chromatiales 135613|Chromatiales S Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - - - - - - - - - - Peptidase_M48,TPR_19 k59_1527041_1 999541.bgla_1g14920 1.14e-30 118.0 COG4313@1|root,COG4313@2|Bacteria,1PC95@1224|Proteobacteria,2VZIG@28216|Betaproteobacteria,1K5VU@119060|Burkholderiaceae 28216|Betaproteobacteria C Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg k59_1295249_2 272568.GDI2776 1.73e-29 113.0 COG0583@1|root,COG0583@2|Bacteria,1MWUD@1224|Proteobacteria,2U05D@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate k59_649300_1 1410620.SHLA_90c000080 4.5e-18 82.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2U1KV@28211|Alphaproteobacteria,4BGMB@82115|Rhizobiaceae 28211|Alphaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate k59_649300_2 1245471.PCA10_07760 1.73e-32 122.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RNNI@1236|Gammaproteobacteria,1YF2A@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily phnW GO:0003674,GO:0003824 2.6.1.112,2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839,ko:K03430 ko00230,ko00250,ko00260,ko00440,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00440,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R04152,R10908 RC00006,RC00008,RC00018,RC00062,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 k59_44957_1 1218352.B597_005770 1.43e-35 140.0 COG0642@1|root,COG3614@1|root,COG2205@2|Bacteria,COG3614@2|Bacteria,1NRP8@1224|Proteobacteria,1T25X@1236|Gammaproteobacteria,1YZWP@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria T signal transduction histidine kinase - - - - - - - - - - - - CHASE,HATPase_c,HisKA,PAS_3,Response_reg k59_544389_1 1500893.JQNB01000001_gene3171 8.67e-22 93.6 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,1X3DY@135614|Xanthomonadales 135614|Xanthomonadales C NADH-quinone oxidoreductase nuoG - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 k59_544389_2 767434.Fraau_1412 8.07e-71 225.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1X2ZD@135614|Xanthomonadales 135614|Xanthomonadales C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB k59_1295379_1 436308.Nmar_1706 1.23e-74 236.0 COG1078@1|root,arCOG04430@2157|Archaea,41T0P@651137|Thaumarchaeota 651137|Thaumarchaeota S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K06885 - - - - ko00000 - - - HD k59_94519_1 1448139.AI20_15730 1.72e-14 68.6 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,1Y4FH@135624|Aeromonadales 135624|Aeromonadales J Binds together with S18 to 16S ribosomal RNA rpsF - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 k59_94519_2 1268237.G114_05470 6.98e-47 150.0 COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria,1Y4Q2@135624|Aeromonadales 135624|Aeromonadales J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR - - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 k59_94519_3 1216007.AOPM01000071_gene1564 1.54e-08 53.1 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria,2Q244@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N k59_544495_1 28229.ND2E_0657 4.55e-14 72.0 COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,2Q6M0@267889|Colwelliaceae 1236|Gammaproteobacteria U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltT - - ko:K03309 - - - - ko00000 2.A.23 - - SDF k59_544495_2 745411.B3C1_08086 9.41e-42 145.0 28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,1RXGW@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3025) - - - - - - - - - - - - DUF3025 k59_1545083_1 34740.HMEL002865-PA 5.06e-128 373.0 COG2367@1|root,2SIVR@2759|Eukaryota 2759|Eukaryota V Beta-lactamase enzyme family - - - - - - - - - - - - Beta-lactamase2 k59_694544_1 1205753.A989_17078 4.1e-70 236.0 COG3250@1|root,COG3250@2|Bacteria,1NYBH@1224|Proteobacteria,1RZPC@1236|Gammaproteobacteria,1XCMD@135614|Xanthomonadales 135614|Xanthomonadales G Glycosyl hydrolases family 2 - - 3.2.1.25 ko:K01192 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000 - - - Glyco_hydro_2,Glyco_hydro_2_C k59_990179_1 644801.Psest_3812 3.53e-55 175.0 COG3296@1|root,COG3296@2|Bacteria,1N8TC@1224|Proteobacteria,1SEZY@1236|Gammaproteobacteria,1Z31I@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria S protein conserved in bacteria - - - ko:K09940 - - - - ko00000 - - - DUF4870 k59_990179_2 243924.LT42_20385 1.83e-16 76.3 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria 1236|Gammaproteobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C k59_1345161_1 266264.Rmet_0210 1.76e-89 289.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,1K4Q5@119060|Burkholderiaceae 28216|Betaproteobacteria EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase ## 2375 queries scanned ## Total time (seconds): 71.99925971031189 ## Rate: 32.99 q/s